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Tytuł:
Transcriptomic profiling of mare endometrium at different stages of endometrosis.
Autorzy:
Szóstek-Mioduchowska A; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland. .
Wójtowicz A; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland.
Sadowska A; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland.
Moza Jalali B; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland.
Słyszewska M; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland.
Łukasik K; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland.
Gurgul A; Center for Experimental and Innovative Medicine, University of Agriculture in Cracow, Cracow, Poland.
Szmatoła T; Center for Experimental and Innovative Medicine, University of Agriculture in Cracow, Cracow, Poland.
Bugno-Poniewierska M; Department of Animal Reproduction, Anatomy and Genomics, University of Agriculture in Cracow, Cracow, Poland.
Ferreira-Dias G; Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
Skarzynski DJ; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences in Olsztyn, Olsztyn, Poland.
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 27; Vol. 13 (1), pp. 16263. Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcriptome*
Interleukin-13*
Pregnancy ; Animals ; Female ; Horses ; Interleukin-17 ; Cytokines/genetics ; Endometrium ; Inflammation/genetics ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preclinical immunological characterization of rademikibart (CBP-201), a next-generation human monoclonal antibody targeting IL-4Rα, for the treatment of Th2 inflammatory diseases.
Autorzy:
Zhang L; Suzhou Connect Biopharmaceuticals, Ltd, East R&D Building, 6 Beijing West Road, Taicang, 214500, China.
Ding Y; Suzhou Connect Biopharmaceuticals, Ltd, East R&D Building, 6 Beijing West Road, Taicang, 214500, China.
Wang Q; Connect Biopharma LLC, 12265 El Camino Real, San Diego, CA, 92130, USA.
Pan W; Suzhou Connect Biopharmaceuticals, Ltd, East R&D Building, 6 Beijing West Road, Taicang, 214500, China.
Wei Z; Connect Biopharma LLC, 12265 El Camino Real, San Diego, CA, 92130, USA.
Smith PA; Connect Biopharma LLC, 12265 El Camino Real, San Diego, CA, 92130, USA.
Yang X; Suzhou Connect Biopharmaceuticals, Ltd, East R&D Building, 6 Beijing West Road, Taicang, 214500, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 31; Vol. 13 (1), pp. 12411. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*/pharmacology
Antibodies, Monoclonal*/therapeutic use
Interleukin-13*
Humans ; Mice ; Animals ; Interleukin-4/metabolism ; Immunoglobulin E ; Th2 Cells ; Mice, Inbred BALB C
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM.
Autorzy:
Fernandez-Martinez D; European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38042, Grenoble, France.; Sanofi R&D, Bio Structure and Biophysics, Centre de Recherche Vitry-Sur-Seine, 94403, Vitry-Sur-Seine Cedex, France.; Pathogenesis of Vascular Infections, Department of Cell Biology and Infection, Institut Pasteur, INSERM, 75015, Paris, France.
Tully MD; European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38042, Grenoble, France.
Leonard G; European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38042, Grenoble, France.
Mathieu M; Sanofi R&D, Bio Structure and Biophysics, Centre de Recherche Vitry-Sur-Seine, 94403, Vitry-Sur-Seine Cedex, France. .
Kandiah E; European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38042, Grenoble, France. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 29; Vol. 13 (1), pp. 8694. Date of Electronic Publication: 2023 May 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*
Interleukin-13*
Cryoelectron Microscopy ; Interleukin-4 ; Antigens ; Epitopes/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potential anthelmintic effect of chitosan on Syphacia muris infecting Wistar rats: biochemical, immunological, and histopathological studies.
Autorzy:
Mostafa NA; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt. nesma_.
Hamdi SAH; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.
Fol MF; Zoology Department, Faculty of Science, Cairo University, Giza, Egypt.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 03; Vol. 14 (1), pp. 2825. Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:
Journal Article
MeSH Terms:
Chitosan*/pharmacology
Chitosan*/chemistry
Oxyuroidea*
Anthelmintics*
Rats ; Animals ; Rats, Wistar ; Interleukin-33 ; Interleukin-13 ; Acetic Acid ; Interleukin-5 ; Immunoglobulin G ; Immunoglobulin E
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immune response to zinc oxide inhalation in metal fume fever, and the possible role of IL-17f.
Autorzy:
Szűcs-Somlyó É; Department of Epidemiology and Infectious Diseases, University of Veterinary Medicine, Istvan str. 2., 1078, Budapest, Hungary.
Lehel J; Department of Food Hygiene, University of Veterinary Medicine, Istvan str. 2., 1078, Budapest, Hungary. .
Májlinger K; Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Bertalan Lajos str. 7., 1111, Budapest, Hungary.; MTA-BME Lendület Composite Research Group, Bertalan Lajos str. 7., 1111, Budapest, Hungary.
Tóth F; University of Veterinary Medicine, Istvan str. 2., 1078, Budapest, Hungary.
Jerzsele Á; Department of Pharmacology and Toxicology, University of Veterinary Medicine, Istvan Str. 2., 1078, Budapest, Hungary.; National Laboratory of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety, University of Veterinary Medicine H-1078, Istvan str. 2., Budapest, Hungary.
Kővágó C; Department of Pharmacology and Toxicology, University of Veterinary Medicine, Istvan Str. 2., 1078, Budapest, Hungary.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 14; Vol. 13 (1), pp. 22239. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Zinc Oxide*/toxicity
Asthma*/chemically induced
Welding*
Mice ; Animals ; Interleukin-13 ; Interleukin-4 ; Cytokines/metabolism ; Immunity ; Inhalation Exposure/adverse effects
SCR Disease Name:
Monday morning fever
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multiple sclerosis susceptibility may be associated with the coding rs20541 (R130Q) IL-13 gene polymorphism in the Polish population.
Autorzy:
Grunwald C; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland. .
Adamska-Patruno E; Clinical Research Support Centre, Medical University of Bialystok, Białystok, Poland. .; Department of Nutriomics, Clinical Research Centre, Medical University of Bialystok, Białystok, Poland. .
Wawrusiewicz-Kurylonek N; Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Białystok, Poland.; Department of Clinical Genetics, Medical University of Bialystok, Białystok, Poland.
Czarnowska A; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland.; Department of Neurology, Medical University of Bialystok, Białystok, Poland.
Snarska K; Department of Clinical Medicine, Medical University of Bialystok, Białystok, Poland.
Dardzińska-Głębocka A; Department of Mechanics and Computer Science, Faculty of Mechanical Engineering, Bialystok University of Technology, Białystok, Poland.
Kapica-Topczewska K; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland.; Department of Neurology, Medical University of Bialystok, Białystok, Poland.
Mirończuk A; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland.
Bazylewicz M; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland.
Kochanowicz J; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland.; Department of Neurology, Medical University of Bialystok, Białystok, Poland.
Krętowski A; Clinical Research Support Centre, Medical University of Bialystok, Białystok, Poland.; Department of Nutriomics, Clinical Research Centre, Medical University of Bialystok, Białystok, Poland.; Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Białystok, Poland.
Kułakowska A; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland.; Department of Neurology, Medical University of Bialystok, Białystok, Poland.
Chorąży M; Department of Neurology and Stroke Department, University Clinical Hospital in Bialystok, Białystok, Poland. .; Department of Neurology, Medical University of Bialystok, Białystok, Poland. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 12; Vol. 13 (1), pp. 22083. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/genetics
Humans ; Case-Control Studies ; Genetic Predisposition to Disease ; Genotype ; Interleukin-13/genetics ; Poland ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unique IL-13Rα2/STAT3 mediated IL-13 regulation detected in lung conventional dendritic cells, 24 h post viral vector vaccination.
Autorzy:
Roy S; Molecular Mucosal Vaccine Immunology Group, Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Liu HY; Molecular Mucosal Vaccine Immunology Group, Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Jaeson MI; Molecular Mucosal Vaccine Immunology Group, Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Deimel LP; Molecular Mucosal Vaccine Immunology Group, Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Ranasinghe C; Molecular Mucosal Vaccine Immunology Group, Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jan 23; Vol. 10 (1), pp. 1017. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dendritic Cells/*immunology
Interleukin-13/*immunology
Interleukin-13 Receptor alpha2 Subunit/*metabolism
STAT3 Transcription Factor/*metabolism
Viral Vaccines/*immunology
Animals ; Female ; Fowlpox virus/immunology ; Interferon-gamma/immunology ; Interleukin-13 Receptor alpha1 Subunit/metabolism ; Lung/cytology ; Lung/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; STAT6 Transcription Factor/metabolism ; Transforming Growth Factor beta1/immunology ; Vaccination ; Vaccines, Synthetic/immunology ; Vaccinia virus/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The association of dietary fibre intake and the IL13 rs20541 polymorphism with the risk of gastric cancer: a case-control study in Korea.
Autorzy:
Thi Tran T; Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi-do, Korea.
Gunathilake M; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi-do, Korea.
Lee J; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi-do, Korea.
Choi IJ; Center for Gastric Cancer, National Cancer Center Hospital, National Cancer Center, Goyang-si, Gyeonggi-do, Korea.
Kim YI; Center for Gastric Cancer, National Cancer Center Hospital, National Cancer Center, Goyang-si, Gyeonggi-do, Korea.
Kim J; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi-do, Korea. .
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Źródło:
European journal of clinical nutrition [Eur J Clin Nutr] 2022 Jul; Vol. 76 (7), pp. 1031-1037. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dietary Fiber*/administration & dosage
Interleukin-13*/genetics
Stomach Neoplasms*/genetics
Stomach Neoplasms*/prevention & control
Case-Control Studies ; Genetic Predisposition to Disease ; Humans ; Male ; Polymorphism, Single Nucleotide ; Republic of Korea
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptional regulation of the IL-13Rα2 gene in human lung fibroblasts.
Autorzy:
Penke LR; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Ouchi H; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Speth JM; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Lugogo N; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Huang YJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Huang SK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Peters-Golden M; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. .; Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, MI, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jan 23; Vol. 10 (1), pp. 1083. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcription, Genetic*
Fibroblasts/*metabolism
Interleukin-13 Receptor alpha2 Subunit/*genetics
Lung/*metabolism
Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Dinoprostone/metabolism ; Gene Expression Regulation ; Humans ; Interleukin-13/genetics ; Interleukin-13/metabolism ; Interleukin-13 Receptor alpha2 Subunit/metabolism ; Lung/cytology ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment.
Autorzy:
Wei CH; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Huang L; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Kreh B; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Liu X; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Tyutyunyk-Massey L; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Kawakami M; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Chen Z; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Shi M; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Kozlov S; Center for Advanced Preclinical Research, Frederick, MD, USA.
Chan KC; Protein Characterization Laboratory, Frederick, MD, USA.
Andresson T; Protein Characterization Laboratory, Frederick, MD, USA.
Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Vuligonda V; Io Therapeutics, Inc., Spring, TX, USA.
Sanders ME; Io Therapeutics, Inc., Spring, TX, USA.
Horowitz A; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hwu P; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Moffitt Cancer Center, Tampa, FL, USA.
Peng W; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dmitrovsky E; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Liu X; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 09; Vol. 13 (1), pp. 14907. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:
CD8-Positive T-Lymphocytes*
Lung Neoplasms*/drug therapy
Animals ; Mice ; Interleukin-13 ; Interleukin-5 ; Tumor Microenvironment ; Receptors, Retinoic Acid ; Tretinoin ; Carcinogenesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms.
Autorzy:
Gotfredsen K; The Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark. .
Liisborg C; The Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark.
Skov V; The Department of Hematology, Zealand University Hospital, Roskilde, Denmark.
Kjær L; The Department of Hematology, Zealand University Hospital, Roskilde, Denmark.
Hasselbalch HC; The Department of Hematology, Zealand University Hospital, Roskilde, Denmark.
Sørensen TL; The Department of Ophthalmology, Zealand University Hospital, Roskilde, Denmark.
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 11; Vol. 13 (1), pp. 4077. Date of Electronic Publication: 2023 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Wet Macular Degeneration*
Neoplasms*
Humans ; Interleukin-4 ; Interleukin-13 ; Angiogenesis Inhibitors ; Interleukin-33 ; Cross-Sectional Studies ; Vascular Endothelial Growth Factor A ; Visual Acuity ; Cytokines ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Haematological indices and immune response profiles in dogs naturally infected and co-infected with Dirofilaria repens and Babesia canis.
Autorzy:
Wężyk D; Department of Eco-Epidemiology of Parasitic Diseases, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1 Street, 02-096, Warsaw, Poland.
Romanczuk K; Department of Cytology, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1 Street, 02-096, Warsaw, Poland.
Rodo A; Department of Pathology and Veterinary Diagnostics, Warsaw University of Life Sciences-SGGW, 159C Nowoursynowska Street, 02-766, Warsaw, Poland.; Lab-Wet, Veterinary Diagnostic Laboratory, ul. Wita Stwosza 30 Street, 02-661, Warsaw, Poland.
Kavalevich D; Department of Eco-Epidemiology of Parasitic Diseases, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1 Street, 02-096, Warsaw, Poland.
Bajer A; Department of Eco-Epidemiology of Parasitic Diseases, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1 Street, 02-096, Warsaw, Poland. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 04; Vol. 13 (1), pp. 2028. Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Babesia*/genetics
Babesiosis*/parasitology
Dirofilaria repens*
Coinfection*/veterinary
Dog Diseases*/epidemiology
Dogs ; Animals ; Interleukin-10 ; Interleukin-13
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-4/IL-13 remodeling pathway of COVID-19 lung injury.
Autorzy:
Vaz de Paula CB; School of Medicine, Postgraduate Program of Health Sciences, Pontifícia Universidade Católica do Paraná-PUCPR, Rua Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil. .
de Azevedo MLV; Laboratory of Experimental Pathology, School of Medicine, Pontifícia Universidade Católica do Paraná-PUCPR, R. Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
Nagashima S; School of Medicine, Postgraduate Program of Health Sciences, Pontifícia Universidade Católica do Paraná-PUCPR, Rua Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
Martins APC; Laboratory of Experimental Pathology, School of Medicine, Pontifícia Universidade Católica do Paraná-PUCPR, R. Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
Malaquias MAS; School of Medicine, Postgraduate Program of Health Sciences, Pontifícia Universidade Católica do Paraná-PUCPR, Rua Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
Miggiolaro AFRDS; School of Medicine, Postgraduate Program of Health Sciences, Pontifícia Universidade Católica do Paraná-PUCPR, Rua Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
da Silva Motta Júnior J; School of Medicine, Postgraduate Program of Health Sciences, Pontifícia Universidade Católica do Paraná-PUCPR, Rua Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
Avelino G; Hospital Marcelino Champagnat, School of Medicine, Pontifical Catholic University of Paraná-PUCPR, R. Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
do Carmo LAP; School of Medicine, Pontifícia Universidade Católica do Paraná-PUCPR, R. Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
Carstens LB; School of Medicine, Pontifícia Universidade Católica do Paraná-PUCPR, R. Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
de Noronha L; Laboratory of Experimental Pathology, School of Medicine, Pontifícia Universidade Católica do Paraná-PUCPR, R. Imaculada Conceição, 1155 - Prado Velho, Curitiba, PR, Brazil.
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Źródło:
Scientific reports [Sci Rep] 2020 Oct 29; Vol. 10 (1), pp. 18689. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coronavirus Infections/*metabolism
Interleukin-13/*metabolism
Interleukin-4/*metabolism
Lung/*metabolism
Pneumonia, Viral/*metabolism
Aged ; Aged, 80 and over ; Biomarkers/metabolism ; COVID-19 ; Coronavirus Infections/pathology ; Female ; Humans ; Interleukin-13/genetics ; Interleukin-4/genetics ; Lung/pathology ; Macrophages/metabolism ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/pathology ; Sphingosine/metabolism ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel single-chain antibody redirects adenovirus to IL13Rα2-expressing brain tumors.
Autorzy:
Kim JW; The Brain Tumor Center, The University of Chicago, Chicago, IL 60637, USA.
Young JS; The Brain Tumor Center, The University of Chicago, Chicago, IL 60637, USA.
Solomaha E; Biophysics Core Facility, The University of Chicago, Chicago, IL 60637, USA.
Kanojia D; The Brain Tumor Center, The University of Chicago, Chicago, IL 60637, USA.
Lesniak MS; The Brain Tumor Center, The University of Chicago, Chicago, IL 60637, USA.
Balyasnikova IV; The Brain Tumor Center, The University of Chicago, Chicago, IL 60637, USA.
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Źródło:
Scientific reports [Sci Rep] 2015 Dec 14; Vol. 5, pp. 18133. Date of Electronic Publication: 2015 Dec 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms/*immunology
Glioma/*immunology
Interleukin-13 Receptor alpha2 Subunit/*immunology
Single-Chain Antibodies/*immunology
Adenoviridae/genetics ; Adenoviridae/metabolism ; Animals ; Binding, Competitive/immunology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; CHO Cells ; Cell Line, Tumor ; Cricetinae ; Cricetulus ; Glioma/drug therapy ; Glioma/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Humans ; Interleukin-13 Receptor alpha1 Subunit/immunology ; Interleukin-13 Receptor alpha1 Subunit/metabolism ; Interleukin-13 Receptor alpha2 Subunit/antagonists & inhibitors ; Interleukin-13 Receptor alpha2 Subunit/metabolism ; Kinetics ; Male ; Mice, Nude ; Microscopy, Confocal ; Protein Binding/immunology ; Single-Chain Antibodies/metabolism ; Single-Chain Antibodies/pharmacology ; Surface Plasmon Resonance ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Insight into the pulmonary molecular toxicity of heated tobacco products using human bronchial and alveolar mucosa models at air-liquid interface.
Autorzy:
Rahman M; Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Irmler M; Institute of Experimental Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), 85764, Neuherberg, Germany.
Introna M; Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Beckers J; Institute of Experimental Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), 85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD E.V.), 85764, Neuherberg, Germany.; Chair of Experimental Genetics, Technical University of Munich, 85354, Freising, Germany.
Palmberg L; Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Johanson G; Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Upadhyay S; Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden. .
Ganguly K; Unit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden. .
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Źródło:
Scientific reports [Sci Rep] 2022 Sep 30; Vol. 12 (1), pp. 16396. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tobacco Products*/analysis
8-Hydroxy-2'-Deoxyguanosine ; Adenosine Diphosphate Ribose ; Aerosols/analysis ; Estrogens ; Histones ; Humans ; Interferon-gamma ; Interleukin-13 ; Interleukin-4 ; Interleukin-8 ; Mucous Membrane/chemistry ; Nicotine/analysis ; Reactive Oxygen Species ; Smoke/analysis ; Superoxides/analysis ; Nicotiana ; alpha-Tocopherol
Czasopismo naukowe
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Tytuł:
Associations between salivary cytokines and oral health, age, and sex in healthy children.
Autorzy:
Rinderknecht C; Department of Oral Surgery, University Center for Dental Medicine, University of Basel, Mattenstrasse 40, 4058, Basel, Switzerland. .
Filippi C; Department of General Pediatric and Adolescent Dentistry, University Center for Dental Medicine, University of Basel, Basel, Switzerland.
Ritz N; Mycobacterial and Migrant Health Research Group, University Children's Hospital Basel and Department of Clinical Research, University of Basel, Basel, Switzerland.; Department of Paediatrics and Paediatric Infectious Diseases, Children's Hospital, Lucerne Cantonal Hospital, Lucerne, Switzerland.; Department of Pediatrics, The Royal Children's Hospital Melbourne, The University of Melbourne, Melbourne, Australia.
Fritschi N; Mycobacterial and Migrant Health Research Group, University Children's Hospital Basel and Department of Clinical Research, University of Basel, Basel, Switzerland.; University Children's Hospital Basel, University of Basel, Basel, Switzerland.
Simmen U; Simmen Statistical Consulting, Basel, Switzerland.
Filippi A; Department of Oral Surgery, University Center for Dental Medicine, University of Basel, Mattenstrasse 40, 4058, Basel, Switzerland.
Diesch-Furlanetto T; Department of Oncology/Haematology, University Children's Hospital Basel UKBB, Basel, Switzerland.
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Źródło:
Scientific reports [Sci Rep] 2022 Sep 26; Vol. 12 (1), pp. 15991. Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytokines*/metabolism
Gingivitis*/metabolism
Adolescent ; Chemokine CXCL10/metabolism ; Child ; Cross-Sectional Studies ; Humans ; Interleukin-10/metabolism ; Interleukin-13/metabolism ; Interleukin-4/metabolism ; Interleukin-5/metabolism ; Interleukin-6/metabolism ; Interleukin-8/metabolism ; Male ; Oral Health ; Saliva/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-13Rα2 mediates PNR-induced migration and metastasis in ERα-negative breast cancer.
Autorzy:
Zhao Z; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA.
Wang L; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA.
Xu W; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA.
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Źródło:
Oncogene [Oncogene] 2015 Mar 19; Vol. 34 (12), pp. 1596-607. Date of Electronic Publication: 2014 Apr 21.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Breast Neoplasms/*pathology
Estrogen Receptor alpha/*metabolism
Interleukin-13 Receptor alpha2 Subunit/*genetics
Orphan Nuclear Receptors/*metabolism
Animals ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Interleukin-13/metabolism ; Interleukin-13 Receptor alpha2 Subunit/metabolism ; MCF-7 Cells ; Mice ; Neoplasm Metastasis ; Neoplasm Transplantation ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein and miRNA profile of circulating extracellular vesicles in patients with primary sclerosing cholangitis.
Autorzy:
Povero D; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.
Tameda M; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California San Diego, 3020 Children's Way, MC 5030, San Diego, CA, 92103-8450, USA.
Eguchi A; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California San Diego, 3020 Children's Way, MC 5030, San Diego, CA, 92103-8450, USA.
Ren W; Genomics and Microarray Core, University of Colorado Denver, Aurora, CO, USA.
Kim J; Department of Biomedical Informatics, University of California San Diego, La Jolla, CA, USA.
Myers R; Gilead Sciences, Inc., Foster City, CA, USA.
Goodman ZD; Inova Fairfax Hospital, Falls Church, VA, USA.
Harrison SA; Pinnacle Clinical Research, San Antonio, TX, USA.
Sanyal AJ; Virginia Commonwealth University, Richmond, VA, USA.
Bosch J; Department of Visceral Surgery and Medicine and Department for Biomedical Research, Inselspital, University of Bern, Bern, Switzerland.; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS)-CIBERehd, University of Barcelona, Barcelona, Spain.
Ohno-Machado L; Department of Biomedical Informatics, University of California San Diego, La Jolla, CA, USA.
Feldstein AE; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California San Diego, 3020 Children's Way, MC 5030, San Diego, CA, 92103-8450, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 22; Vol. 12 (1), pp. 3027. Date of Electronic Publication: 2022 Feb 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholangitis, Sclerosing/*diagnosis
Extracellular Vesicles/*genetics
Extracellular Vesicles/*metabolism
Interleukin-13 Receptor alpha1 Subunit/*genetics
Interleukin-13 Receptor alpha1 Subunit/*metabolism
MicroRNAs/*genetics
MicroRNAs/*metabolism
Adult ; Aged ; Biomarkers/blood ; Female ; Gene Expression ; Humans ; Liver Cirrhosis/diagnosis ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prenatal antioxidant-enriched and pro-oxidant-contained food, IL4 and IL13 pathway genes, and cord blood IgE.
Autorzy:
Chen CH; Department of Pediatrics, Fu Jen Catholic University Hospital, Fu Jen Catholic University, New Taipei City, Taiwan.; School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.; Department of Pediatrics, Min-Sheng General Hospital, Taoyüan City, Taiwan.
Lee YL; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Wu MH; Department of Laboratory Medicine, Min-Sheng General Hospital, Taoyüan City, Taiwan.
Chen PJ; Department of Obstetrics and Gynecology, Min-Sheng General Hospital, Taoyüan City, Taiwan.
Wei TS; Department of Obstetrics and Gynecology, Min-Sheng General Hospital, Taoyüan City, Taiwan.
Tseng CI; Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.
Chen WJ; Centers of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan. .; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan. .; Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2884. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diet*
Food Analysis*
Antioxidants/*administration & dosage
Eating/*physiology
Fetal Blood/*metabolism
Immunoglobulin E/*blood
Interleukin-13/*genetics
Interleukin-13/*metabolism
Interleukin-4/*genetics
Interleukin-4/*metabolism
Maternal Nutritional Physiological Phenomena/*physiology
Maternal-Fetal Exchange/*physiology
Prenatal Exposure Delayed Effects/*blood
Reactive Oxygen Species/*administration & dosage
Signal Transduction/*genetics
Signal Transduction/*physiology
Female ; Genetic Predisposition to Disease/genetics ; Humans ; Pregnancy ; Pregnancy Trimester, Third ; Surveys and Questionnaires
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HDAC6 is a prognostic biomarker that mediates IL-13 expression to regulate macrophage polarization through AP-1 in oral squamous cell carcinoma.
Autorzy:
Tseng CC; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, 80424, Taiwan.; Department of Dentistry, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung, 81342, Taiwan.
Huang SY; College of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Tsai HP; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.
Wu CW; Department of Medical Research, E-Da Hospital/E-Da Cancer Hospital, I-Shou University, Kaohsiung, 82445, Taiwan.
Hsieh TH; Department of Medical Research, E-Da Hospital/E-Da Cancer Hospital, I-Shou University, Kaohsiung, 82445, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jun 22; Vol. 12 (1), pp. 10513. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histone Deacetylase 6*/genetics
Histone Deacetylase 6*/metabolism
Macrophages*/metabolism
Mouth Neoplasms*/genetics
Mouth Neoplasms*/pathology
Squamous Cell Carcinoma of Head and Neck*/genetics
Squamous Cell Carcinoma of Head and Neck*/pathology
Biomarkers/metabolism ; Humans ; Interleukin-13/metabolism ; Macrophage Activation ; Prognosis ; Transcription Factor AP-1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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