Temat: "interleukin-2" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Astragalus root increases Treg and Th17 involvement in embryo implantation and pregnancy maintenance by decreasing CTLA-4 Tregs.
Autorzy:: Kobayashi K; Division of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Miyagi , Japan.
Sasaki K; Division of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Miyagi , Japan.; Pokaż więcej
Źródło:: Drug discoveries & therapeutics [Drug Discov Ther] 2024 Mar 20; Vol. 18 (1), pp. 24-33. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:: Journal Article
MeSH Terms:: T-Lymphocytes, Regulatory*
Interleukin-2*/pharmacology
Pregnancy ; Female ; Mice ; Animals ; CTLA-4 Antigen ; Th17 Cells ; Embryo Implantation ; Pregnancy Maintenance

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Skocz do pozycji: 2.

Tytuł:: Mathematical modeling and control of lung cancer with IL2 cytokine and anti-PD-L1 inhibitor effects for low immune individuals.
Autorzy:: Ahmad A; Department of Mathematics, Ghazi University, D G Khan, Pakistan.
Kulachi MO; Department of Mathematics, Ghazi University, D G Khan, Pakistan.
Farman M; Department of Mathematics, Faculty of Arts and Sciences, Near East University, Northern Cyprus, Turkey.; Department of Computer Science and Mathematics, Lebanese American University, Beirut, Lebanon.
Junjua MU; School of Mathematical Sciences, Zhejiang Normal University, Jinhua, Zhejiang, China.
Bilal Riaz M; IT4Innovations, VSB-Technical University of Ostrava, Ostrava, Czech Republic.
Riaz S; Mathematical Research Center, Faculty of Arts and Sciences, Near East University, Northern Cyprus, Turkey.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 14; Vol. 19 (3), pp. e0299560. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-2*
Lung Neoplasms*/drug therapy
Humans ; Cytokines ; Models, Theoretical ; Fractals

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Skocz do pozycji: 3.

Tytuł:: Assessing the Causal Relationship between Genetically Determined Inflammatory Cytokines and Parkinson's Disease Risk: A Bidirectional Two-Sample Mendelian Randomization Study.
Autorzy:: Xue H; Department of Neurology, Sichuan Taikang Hospital, Chengdu, Sichuan 610213, China.
Luo Q; Department of Dermatology, Jian Yang Hospital of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Chen J; Sichuan University of Science and Engineering, Zigong, Sichuan, China.
Fan W; Department of Neurology, Sichuan Taikang Hospital, Chengdu, Sichuan 610213, China.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2024 Feb 29; Vol. 2024, pp. 9069870. Date of Electronic Publication: 2024 Feb 29 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-2*
Parkinson Disease*/genetics
Humans ; Interferon-gamma ; Interleukin-17 ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Causality

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Skocz do pozycji: 4.

Tytuł:: Efficacy, safety and the lymphocyte subsets changes of low-dose IL-2 in patients with systemic lupus erythematosus: A systematic review and meta-analysis.
Autorzy:: Su QY; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Provincial Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China.; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China.
Luo J; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Provincial Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China.; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China.
Wang XM; Shanxi Provincial Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China.; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China.
Di JK; Shanxi Provincial Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China.; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China.
Cao YX; Shanxi Provincial Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China.; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China.
Zhang SX; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Provincial Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China.; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China.; Pokaż więcej
Źródło:: Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Jan; Vol. 12 (1), pp. e1165.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:: Interleukin-2*/therapeutic use
Lupus Erythematosus, Systemic*/drug therapy
Humans ; CD8-Positive T-Lymphocytes ; Cell Differentiation ; Lymphocyte Subsets

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Skocz do pozycji: 5.

Tytuł:: Human IL-2Rɑ subunit binding modulation of IL-2 through a decline in electrostatic interactions: A computational and experimental approach.
Autorzy:: Beig Parikhani A; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran.
Bagherzadeh K; Stem Cell and Regenerative Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.; Eye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Dehghan R; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran.
Biglari A; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Shokrgozar MA; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Riazi Rad F; Department of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Zeinali S; Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Talebkhan Y; Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Ajdary S; Department of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Ahangari Cohan R; Department of Nanobiotechnology, New Technologies Research Group, Pasteur Institute of Iran, Tehran, Iran.
Behdani M; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Feb 25; Vol. 17 (2), pp. e0264353. Date of Electronic Publication: 2022 Feb 25 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-2 Receptor alpha Subunit*/chemistry
Interleukin-2 Receptor alpha Subunit*/metabolism
Molecular Docking Simulation*
Molecular Dynamics Simulation*
Static Electricity*
Leukocytes, Mononuclear/*metabolism
Humans ; Interleukin-2/chemistry ; Interleukin-2/metabolism ; Protein Binding

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Skocz do pozycji: 6.

Tytuł:: NFAT Factors Are Dispensable for the Development but Are Critical for the Maintenance of Foxp3 Regulatory T Cells.
Autorzy:: Barahona de Brito C; Peninsula School of Medicine, University of Plymouth, Plymouth PL6 8BU, UK.; Department of Biology and Biochemistry, University of Bath, Bath BA2 7AX, UK.
Patra AK; Peninsula School of Medicine, University of Plymouth, Plymouth PL6 8BU, UK.; Department of Molecular Pathology, Institute of Pathology, University of Würzburg, Josef Schneider-Str. 2, 97080 Würzburg, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Apr 20; Vol. 11 (9). Date of Electronic Publication: 2022 Apr 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-2*/metabolism
T-Lymphocytes, Regulatory*/metabolism
Animals ; Forkhead Transcription Factors/metabolism ; Mice ; Receptors, Interleukin-2/genetics ; Receptors, Interleukin-2/metabolism ; TCF Transcription Factors/metabolism

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Skocz do pozycji: 7.

Tytuł:: Efficacy and antitumor activity of a mutant type of interleukin 2.
Autorzy:: Dehghan R; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, 1316543551, Tehran, Iran.
Beig Parikhani A; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, 1316543551, Tehran, Iran.
Zeinali S; Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Shokrgozar M; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Amanzadeh A; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Ajdary S; Department of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Ahangari Cohan R; Department of Nanobiotechnology, New Technologies Research Group, Pasteur Institute of Iran, Tehran, Iran.
Talebkhan Y; Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, 1316543551, Tehran, Iran. .
Behdani M; Venom and Biotherapeutics Molecules Laboratory, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, 1316543551, Tehran, Iran. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Mar 30; Vol. 12 (1), pp. 5376. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-2*/genetics
Interleukin-2*/metabolism
Interleukin-2*/pharmacology
Melanoma*/metabolism
Humans ; Killer Cells, Natural/metabolism ; Leukocytes, Mononuclear/metabolism ; Receptors, Interleukin-2/metabolism

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Skocz do pozycji: 8.

Tytuł:: Accumulation of Inflammatory Mediators in the Normal Pericardial Fluid.
Autorzy:: El-Diasty MM; Cardiac Surgery Department, Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.; Division of Clinical Biochemistry, University Hospital, 15706 Santiago de Compostela, Spain.
Rodríguez J; Division of Clinical Biochemistry, University Hospital, 15706 Santiago de Compostela, Spain.
Pérez L; Division of Clinical Biochemistry, University Hospital, 15706 Santiago de Compostela, Spain.
Eiras S; Laboratory of Cardiovascular Research, University Hospital, 15706 Santiago de Compostela, Spain.
Fernández AL; Division of Cardiac Surgery, University Hospital, Department of Surgery, University of Santiago de Compostela, 15706 Santiago de Compostela, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:: Journal Article
MeSH Terms:: Pericardial Fluid*
Interleukin-2*
Male ; Humans ; Aged ; Female ; P-Selectin ; Interleukin-4 ; Vascular Endothelial Growth Factor A ; Epidermal Growth Factor ; Interleukin-6 ; Prospective Studies ; Tumor Necrosis Factor-alpha ; Pericardium

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Skocz do pozycji: 9.

Tytuł:: Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases.
Autorzy:: Wu WC; SinoMab BioScience Limited, Units 303 and 305 to 307, No. 15 Science Park West Avenue, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong.
Shiu C; SinoMab BioScience Limited, Units 303 and 305 to 307, No. 15 Science Park West Avenue, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong.
Tong TK; SinoMab BioScience Limited, Units 303 and 305 to 307, No. 15 Science Park West Avenue, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong.
Leung SO; SinoMab BioScience Limited, Units 303 and 305 to 307, No. 15 Science Park West Avenue, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong.
Hui CW; SinoMab BioScience Limited, Units 303 and 305 to 307, No. 15 Science Park West Avenue, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2023 Dec 08; Vol. 2023, pp. 8924603. Date of Electronic Publication: 2023 Dec 08 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-2*/metabolism
Autoimmune Diseases*/drug therapy
Humans ; Interleukin-15 ; Cytokines/metabolism ; Janus Kinases/metabolism ; Killer Cells, Natural ; Janus Kinase 3

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Skocz do pozycji: 10.

Tytuł:: Exploring the causal relationship between inflammatory cytokines and migraine: a bidirectional, two-sample Mendelian randomization study.
Autorzy:: Fu C; Department of Gastroenterology, Anqing Municipal Hospital, 352#, Renmin Road, Anqing, Anhui, 246000, People's Republic of China.
Chen Y; Department of Gastroenterology, Anqing Municipal Hospital, 352#, Renmin Road, Anqing, Anhui, 246000, People's Republic of China.
Xu W; Department of Gastroenterology, Anqing Municipal Hospital, 352#, Renmin Road, Anqing, Anhui, 246000, People's Republic of China.
Zhang Y; Department of Gastroenterology, Anqing Municipal Hospital, 352#, Renmin Road, Anqing, Anhui, 246000, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Nov 08; Vol. 13 (1), pp. 19394. Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-2*/genetics
Migraine Disorders*/genetics
Humans ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Causality

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Skocz do pozycji: 11.

Tytuł:: Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles.
Autorzy:: Rojas G; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba. .
Relova-Hernández E; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Pérez-Riverón A; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Castro-Martínez C; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Diaz-Bravo O; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Infante YC; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Gómez T; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Solozábal J; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
DíazBravo AB; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Schubert M; Technische Universität Braunschweig, Institute of Biochemistry, Biotechnology and Bioinformatics, Department of Biotechnology, Spielmannstraße 7, 38106, Braunschweig, Germany.
Becker M; Technische Universität Braunschweig, Institute of Biochemistry, Biotechnology and Bioinformatics, Department of Biotechnology, Spielmannstraße 7, 38106, Braunschweig, Germany.
Pérez-Massón B; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Pérez-Martínez D; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Alvarez-Arzola R; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Guirola O; Center of Genetic Engineering and Biotechnology, Ave 31 e/ 158 y 190, apartado 6162, Playa, CP 11300, La Habana, Cuba.
Chinea G; Center of Genetic Engineering and Biotechnology, Ave 31 e/ 158 y 190, apartado 6162, Playa, CP 11300, La Habana, Cuba.
Graca L; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal.
Dübel S; Technische Universität Braunschweig, Institute of Biochemistry, Biotechnology and Bioinformatics, Department of Biotechnology, Spielmannstraße 7, 38106, Braunschweig, Germany.
León K; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.
Carmenate T; Center of Molecular Immunology, calle 216 esq 15, apartado 16040, Atabey, Playa, CP 11300, La Habana, Cuba.; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2023 Aug 09; Vol. 6 (1), pp. 828. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Peptide Library*
Interleukin-2 Receptor beta Subunit*/chemistry
Interleukin-2*/chemistry
Interleukin-2*/genetics
Interleukin-2*/metabolism
Directed Molecular Evolution*/methods
Humans ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Protein Domains ; Animals ; Mice ; Cell Line, Tumor

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Skocz do pozycji: 12.

Tytuł:: Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy.
Autorzy:: Tumas S; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Meldgaard TS; Department of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Vaaben TH; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Suarez Hernandez S; Department of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Rasmussen AT; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Vazquez-Uribe R; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Hadrup SR; Department of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Sommer MOA; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 02; Vol. 13 (1), pp. 12506. Date of Electronic Publication: 2023 Aug 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Immunotherapy*
Interleukin-2*/genetics
Interleukin-2*/pharmacology
Neoplasms*/therapy
Animals ; Mice ; Escherichia coli

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Skocz do pozycji: 13.

Tytuł:: The Important Role of Interleukin-2 in COVID-19.
Autorzy:: Ghanbari Naeini L; Gulf Medical University, Ajman, UAE.
Abbasi L; Guilan University of Medical Sciences, Rasht, Iran.
Karimi F; Behbahan Faculty of Medical Sciences, Behbahan, Iran.
Kokabian P; School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abdi Abyaneh F; Kashan University of Medical Sciences, Kashan, Iran.
Naderi D; Faculty of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2023 Aug 22; Vol. 2023, pp. 7097329. Date of Electronic Publication: 2023 Aug 22 (Print Publication: 2023).
Typ publikacji:: Journal Article; Review
MeSH Terms:: COVID-19*/immunology
Interleukin-2*/immunology
Humans ; Cytokine Release Syndrome ; Cytokines

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Skocz do pozycji: 14.

Tytuł:: The Molecular Mechanism of Positive Allosteric Modulation at the Dopamine D1 Receptor.
Autorzy:: Goldberg A; Computational Chemistry and Molecular Biophysics Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.
Xie B; Computational Chemistry and Molecular Biophysics Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.
Shi L; Computational Chemistry and Molecular Biophysics Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 16; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-2*
Mental Disorders*
Humans ; Receptors, Dopamine D1 ; Binding Sites ; Molecular Dynamics Simulation

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Skocz do pozycji: 15.

Tytuł:: Soluble interleukin-2 receptor as a predictive and prognostic marker for patients with familial breast cancer.
Autorzy:: Gonda K; Department of Medicine, Daido Obesity and Metabolism Research Center, Japan.; Department of Medicine, Daido Central Hospital, Japan.; Department of Bioregulation and Pharmacological Medicine, 12775Fukushima Medical University, Japan.; 12775Department of Surgery, Fukushima Medical University, Japan.
Horita S; Department of Bioregulation and Pharmacological Medicine, 12775Fukushima Medical University, Japan.
Maejima Y; Department of Bioregulation and Pharmacological Medicine, 12775Fukushima Medical University, Japan.
Takenoshita S; 12775Department of Surgery, Fukushima Medical University, Japan.
Shimomura K; Department of Bioregulation and Pharmacological Medicine, 12775Fukushima Medical University, Japan.; Pokaż więcej
Źródło:: Science progress [Sci Prog] 2021 Jul-Sep; Vol. 104 (3), pp. 368504211039590.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-2*
Triple Negative Breast Neoplasms*
Breast Neoplasms ; C-Reactive Protein ; Humans ; Interleukin-17 ; Ligands ; Prognosis ; Receptors, Interleukin-2 ; Vascular Endothelial Growth Factor A
SCR Disease Name:: Breast Cancer, Familial

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Skocz do pozycji: 16.

Tytuł:: Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies.
Autorzy:: Muhammad S; Department of Thoracic Surgery, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Laboratory of Translational Medicine, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Department of Colorectal Surgery, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, China.; Department of Colorectal Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China.; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Fan T; Department of Thoracic Surgery, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Laboratory of Translational Medicine, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Hai Y; Department of Children's and Adolescent Health, Public Health College of Harbin Medical University, 157 Baojian Road, Harbin, 150081, China.
Gao Y; Department of Thoracic Surgery, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .; Laboratory of Translational Medicine, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .; Central Laboratory & Shenzhen Key Laboratory of Epigenetics and Precision Medicine for Cancers, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, 518116, China. .
He J; Department of Thoracic Surgery, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .; Laboratory of Translational Medicine, National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .; Central Laboratory & Shenzhen Key Laboratory of Epigenetics and Precision Medicine for Cancers, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, 518116, China. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2023 Jul 29; Vol. 22 (1), pp. 121. Date of Electronic Publication: 2023 Jul 29.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-2*/genetics
Interleukin-2*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Carcinogenesis ; Immunotherapy ; Cell Cycle ; Tumor Microenvironment

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Skocz do pozycji: 17.

Tytuł:: HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter.
Autorzy:: Anastasopoulou S; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Georgakopoulos T; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Mouzaki A; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 May 24; Vol. 13 (6). Date of Electronic Publication: 2023 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Infections*/genetics
HIV Infections*/immunology
HIV Infections*/virology
HIV-1*/genetics
HIV-1*/metabolism
Interleukin-2*/genetics
Interleukin-2*/metabolism
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Humans ; Gene Expression Regulation, Viral ; Transcription Factors/metabolism ; Transcription, Genetic ; Transcriptional Activation

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Skocz do pozycji: 18.

Tytuł:: Exploring the impact of nano-Se and nano-clay feed supplements on interleukin genes, immunity and growth rate in European Sea Bass (Dicentrarchus labrax).
Autorzy:: Khaled AA; Animal and Fish Production Department, Faculty of Agriculture (Saba Basha), Alexandria University, Alexandria City, 21531, Egypt.
Shabaan AM; Chemistry Department, Biochemistry Division, Faculty of Science, El-Fayoum University, El-Fayoum, Egypt.
Hammad SM; Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications, New Borg El Arab, Alexandria, 21934, Egypt.
Hafez EE; Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications, New Borg El Arab, Alexandria, 21934, Egypt.
Saleh AA; Animal and Fish Production Department, Faculty of Agriculture (Alshatby), Alexandria University, Alexandria City, 11865, Egypt. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2631. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Bass*/metabolism
Animals ; Lymphotoxin-alpha/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-2/genetics ; Interleukin-2/metabolism ; Interleukin-6/metabolism ; Interleukin-12/metabolism

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Skocz do pozycji: 19.

Tytuł:: Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity.
Autorzy:: Song D; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Liu X; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Dong C; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Wang Q; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Sha C; State Key Laboratory of Long-Acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co. Ltd, Yantai, 264670, People's Republic of China.
Liu C; Shuimu BioSciences Ltd., Beijing, 102206, People's Republic of China.
Ning Z; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Han J; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Liu H; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Zong M; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Zhao Y; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Li Y; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Liu G; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Shao X; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China.
Dou C; Antibody Research and Development Center, Shandong Boan Biotechnology Co., Ltd., Yantai, 264670, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 25; Vol. 11 (1), pp. 22966. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents, Immunological*/chemistry
Antineoplastic Agents, Immunological*/immunology
Antineoplastic Agents, Immunological*/metabolism
Antineoplastic Agents, Immunological*/pharmacology
Neoplasms*/immunology
Neoplasms*/therapy
Interleukin-2 Receptor alpha Subunit/*immunology
Animals ; Cell Line ; Cryoelectron Microscopy ; Disease Models, Animal ; Humans ; Immunotherapy/methods ; Interleukin-2/metabolism ; Interleukin-2 Receptor alpha Subunit/metabolism ; Macaca fascicularis ; Mice ; T-Lymphocytes, Regulatory/immunology ; Tumor Microenvironment/immunology

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Skocz do pozycji: 20.

Tytuł:: JAK1 Pseudokinase V666G Mutant Dominantly Impairs JAK3 Phosphorylation and IL-2 Signaling.
Autorzy:: Grant AH; Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Rodriguez AC; Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Rodriguez Moncivais OJ; Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Sun S; Department of Physics, The University of Texas at El Paso, El Paso, TX 79968, USA.; Computational Science Program, The University of Texas at El Paso, El Paso, TX 79968, USA.
Li L; Department of Physics, The University of Texas at El Paso, El Paso, TX 79968, USA.; Computational Science Program, The University of Texas at El Paso, El Paso, TX 79968, USA.
Mohl JE; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.; Department of Mathematical Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.
Leung MY; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.; Computational Science Program, The University of Texas at El Paso, El Paso, TX 79968, USA.; Department of Mathematical Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.
Kirken RA; Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Rodriguez G; Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.; Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-2*/genetics
Interleukin-2*/metabolism
Leukemia*
Humans ; Phosphorylation ; Janus Kinase 1/genetics ; Janus Kinase 1/metabolism ; Signal Transduction ; Janus Kinases/metabolism ; Janus Kinase 3/genetics ; Janus Kinase 3/metabolism

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