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Tytuł:
The Immunomodulatory Effects of Sulforaphane in Exercise-Induced Inflammation and Oxidative Stress: A Prospective Nutraceutical.
Autorzy:
Ruhee RT; Research Fellow of Japan Society for the Promotion of Sciences, Tokyo 102-0083, Japan.
Suzuki K; Faculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 01; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Oxidative Stress*
Isothiocyanates*/pharmacology
Isothiocyanates*/therapeutic use
Animals ; Humans ; Prospective Studies ; Inflammation/drug therapy ; Sulfoxides/pharmacology ; Dietary Supplements ; NF-E2-Related Factor 2/metabolism
Czasopismo naukowe
Tytuł:
Balanced activation of Nrf-2/ARE mediates the protective effect of sulforaphane on keratoconus in the cell mechanical microenvironment.
Autorzy:
Liu R; Department of Ophthalmology, Peking University First Hospital, Beijing, 100034, People's Republic of China.; People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Henan Eye Hospital, Zhengzhou, 450003, People's Republic of China.
Ma R; People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Henan Eye Hospital, Zhengzhou, 450003, People's Republic of China.
Yan X; Department of Ophthalmology, Peking University First Hospital, Beijing, 100034, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 23; Vol. 14 (1), pp. 6937. Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:
Journal Article
MeSH Terms:
Keratoconus*/drug therapy
Keratoconus*/metabolism
Sulfoxides*
Isothiocyanates*
Humans ; Antioxidants/metabolism ; NF-E2-Related Factor 2/metabolism ; Reactive Oxygen Species/metabolism ; Antioxidant Response Elements ; Hydrogen Peroxide/metabolism ; Cornea/metabolism
Czasopismo naukowe
Tytuł:
Sulforaphane-Enriched Extracts from Broccoli Exhibit Antimicrobial Activity against Plant Pathogens, Promising a Natural Antimicrobial Agent for Crop Protection.
Autorzy:
He L; College of Life Sciences, Nankai University, Tianjin 300071, China.
Jiang H; Tianjin Academy of Agricultural Sciences, Tianjin 300380, China.
Li Y; College of Life Sciences, Nankai University, Tianjin 300071, China.
Zhang X; College of Life Sciences, Nankai University, Tianjin 300071, China.
Sun W; College of Life Sciences, Nankai University, Tianjin 300071, China.
Liu C; College of Life Sciences, Nankai University, Tianjin 300071, China.
Zhao Z; College of Life Sciences, Nankai University, Tianjin 300071, China.
Yun C; College of Life Sciences, Nankai University, Tianjin 300071, China.
Li H; College of Horticulture and Landscape, Tianjin Agricultural University, Tianjin 300384, China.
Wang C; College of Life Sciences, Nankai University, Tianjin 300071, China.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 14; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Brassica*/metabolism
Anti-Infective Agents*/pharmacology
Anti-Infective Agents*/metabolism
Sulfoxides*
Isothiocyanates*
Crop Protection ; Reactive Oxygen Species/metabolism ; Plant Extracts/pharmacology ; Plant Extracts/metabolism
Czasopismo naukowe
Tytuł:
Optimizing combination therapy in prostate cancer: mechanistic insights into the synergistic effects of Paclitaxel and Sulforaphane-induced apoptosis.
Autorzy:
Habib TN; Molecular Genetics Lab, Department of Zoology, Faculty of Science, Sohag University, Sohag, Egypt. .
Altonsy MO; Molecular Genetics Lab, Department of Zoology, Faculty of Science, Sohag University, Sohag, Egypt.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, T2N 4N1, Canada.
Ghanem SA; Molecular Genetics Lab, Department of Zoology, Faculty of Science, Sohag University, Sohag, Egypt.
Salama MS; Department of Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt.
Hosny MA; Molecular Genetics Lab, Department of Zoology, Faculty of Science, Sohag University, Sohag, Egypt.
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Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2024 Mar 04; Vol. 25 (1), pp. 5. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Prostatic Neoplasms*/drug therapy
Sulfoxides*
Isothiocyanates*
Male ; Humans ; bcl-2-Associated X Protein ; Caspase 3 ; Proto-Oncogene Proteins c-bcl-2
Czasopismo naukowe
Tytuł:
Bioaccessible Organosulfur Compounds in Broccoli Stalks Modulate the Inflammatory Mediators Involved in Inflammatory Bowel Disease.
Autorzy:
Costa-Pérez A; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Sánchez-Bravo P; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.; Centro de Investigación e Innovación Agroalimentaria y Agroambiental (CIAGRO), Universidad Miguel Hernández de Elche (UMH), Carretera de Beniel km 3.2, 03312 Orihuela, Alicante, Spain.
Medina S; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Domínguez-Perles R; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
García-Viguera C; Laboratorio de Fitoquímica y Alimentos Saludables (LabFAS), CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 08; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Brassica*
Inflammatory Bowel Diseases*/drug therapy
Glucosinolates*
Indoles*
Sulfoxides*
Isothiocyanates*
Humans ; Caco-2 Cells ; Cytokines ; Inflammation Mediators ; Anti-Inflammatory Agents/pharmacology
Czasopismo naukowe
Tytuł:
The Dual Role of Sulforaphane-Induced Cellular Stress-A Systems Biological Study.
Autorzy:
Holczer M; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
Besze B; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
Lehel A; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
Kapuy O; Department of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1085 Budapest, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 19; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Isothiocyanates*/pharmacology
Endoplasmic Reticulum Stress*
Cell Death ; Sulfoxides/pharmacology ; Autophagy ; Apoptosis
Czasopismo naukowe
Tytuł:
Stable Sulforaphane Targets the Early Stages of Osteoclast Formation to Engender a Lasting Functional Blockade of Osteoclastogenesis.
Autorzy:
Louka P; Skeletal Biology Group, Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, UK.
Orriss IR; Skeletal Biology Group, Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, UK.
Pitsillides AA; Skeletal Biology Group, Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, UK.
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Źródło:
Cells [Cells] 2024 Jan 16; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Osteoclasts*
Osteogenesis*
Sulfoxides*
Isothiocyanates*
Animals ; Mice ; NF-E2-Related Factor 2 ; NF-kappa B
Czasopismo naukowe
Tytuł:
Sulforaphane Is Protective against Warm Ischemia/Reperfusion Injury and Partial Hepatectomy in Rats.
Autorzy:
Nakatake R; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Okuyama T; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Hashimoto Y; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Ishizaki M; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Yanagida H; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Kitade H; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Yoshizawa K; Department of Innovative Food Sciences, School of Food Sciences and Nutrition, Mukogawa Women's University, 6-46 Ikebiraki-cho, Nishinomiya 663-8558, Hyogo, Japan.
Nishizawa M; Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, 1-1-1 Nojihigashi, Kusatsu 525-8577, Shiga, Japan.
Sekimoto M; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 01; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 01.
Typ publikacji:
Journal Article
MeSH Terms:
Hepatectomy*
Reperfusion Injury*/drug therapy
Reperfusion Injury*/prevention & control
Sulfoxides*
Isothiocyanates*
Animals ; Rats ; NF-kappa B ; Tumor Necrosis Factor-alpha ; Warm Ischemia ; Inflammation Mediators ; Interleukin-1beta/genetics ; Ischemia
Czasopismo naukowe
Tytuł:
Sulforaphane's Multifaceted Potential: From Neuroprotection to Anticancer Action.
Autorzy:
Otoo RA; Division of Radiation Health, University of Arkansas for Medical Sciences, 4301 West Markham, Suite 441B-2, Little Rock, AR 72205, USA.; Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 West Markham, Suite 441B-2, Little Rock, AR 72205, USA.; Neurobiology & Developmental Sciences, University of Arkansas for Medical Sciences, 4301 West Markham, Suite 441B-2, Little Rock, AR 72205, USA.
Allen AR; Division of Radiation Health, University of Arkansas for Medical Sciences, 4301 West Markham, Suite 441B-2, Little Rock, AR 72205, USA.; Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, 4301 West Markham, Suite 441B-2, Little Rock, AR 72205, USA.; Neurobiology & Developmental Sciences, University of Arkansas for Medical Sciences, 4301 West Markham, Suite 441B-2, Little Rock, AR 72205, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 01; Vol. 28 (19). Date of Electronic Publication: 2023 Oct 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neuroprotection*
Isothiocyanates*/pharmacology
Isothiocyanates*/therapeutic use
Sulfoxides ; Histone Deacetylases/metabolism
Czasopismo naukowe
Tytuł:
Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial.
Autorzy:
Ou J; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Smith RC; Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.; Department of Psychiatry, New York University School of Medicine, New York, NY, USA.
Tobe RH; Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.; Department of Psychiatry, Columbia University, New York, NY, USA.
Lin J; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Arriaza J; School of Professional Studies, New York University, New York, NY, USA.
Fahey JW; Departments of Medicine, Psychiatry and Behavioral Sciences, and Pharmacology & Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA.
Liu R; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Zeng Y; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Liu Y; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Huang L; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Shen Y; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Li Y; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China.; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China.; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China.; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China.
Cheng D; The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, Guangdong, China.
Cornblatt B; Nutramax Laboratories, Consumer Care, Inc., Edgewood, MD, USA.
Davis JM; Department of Psychiatry, University of Illinois, Psychiatric Institute, Chicago, IL, USA.
Zhao J; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China. .; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China. .; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China. .; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China. .
Wu R; Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China. .; Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China. .; China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China. .; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China. .; Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. .
Jin H; Department of Psychiatry, University of California San Diego and Psychiatric Service, VA San Diego Healthcare System, San Diego, CA, USA. .
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Źródło:
Journal of autism and developmental disorders [J Autism Dev Disord] 2024 Feb; Vol. 54 (2), pp. 628-641. Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article
MeSH Terms:
Autism Spectrum Disorder*/drug therapy
Child ; Humans ; Child, Preschool ; Treatment Outcome ; Isothiocyanates/pharmacology ; Isothiocyanates/therapeutic use ; Sulfoxides/therapeutic use ; Double-Blind Method
Czasopismo naukowe
Tytuł:
Comparative Studies of Extracts Obtained from Brassica oleracea L. Plants at Different Stages of Growth by Isolation and Determination of Isothiocyanates: An Assessment of Chemopreventive Properties of Broccoli.
Autorzy:
Ligor M; Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarina Street, 87-100 Toruń, Poland.
Szultka-Młyńska M; Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarina Street, 87-100 Toruń, Poland.
Rafińska K; Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarina Street, 87-100 Toruń, Poland.
Cwudzińska A; Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarina Street, 87-100 Toruń, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 20; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Brassica*/chemistry
Antineoplastic Agents*
Isothiocyanates/pharmacology ; Isothiocyanates/chemistry ; Plant Extracts/chemistry ; Cell Line ; Sulfoxides ; Glucosinolates/metabolism
Czasopismo naukowe
Tytuł:
Toxic effects of trace phenol/guanidine isothiocyanate (P/GI) on cells cultured nearby in covered 96-well plates.
Autorzy:
Snedden M; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, 2650 Ridge Ave, Suite 1538, Evanston, IL, 60201, USA.
Singh L; Department of Statistics, NorthShore University HealthSystem, Evanston, IL, USA.
Kyathanahalli C; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, 2650 Ridge Ave, Suite 1538, Evanston, IL, 60201, USA.; Department of Obstetrics and Gynecology, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.
Hirsch E; Department of Obstetrics and Gynecology, NorthShore University HealthSystem, 2650 Ridge Ave, Suite 1538, Evanston, IL, 60201, USA. .; Department of Obstetrics and Gynecology, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA. .
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Źródło:
BMC biotechnology [BMC Biotechnol] 2022 Nov 25; Vol. 22 (1), pp. 35. Date of Electronic Publication: 2022 Nov 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Phenol*
Isothiocyanates*/pharmacology
Isothiocyanates*/metabolism
Mice ; Animals ; Phenols/metabolism ; Macrophages/metabolism
Czasopismo naukowe
Tytuł:
Sulforaphane attenuates irradiation induced testis injury in mice.
Autorzy:
Ran Y; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Duan N; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Gao Z; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Liu Y; Department of Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Liu X; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Xue B; Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
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Źródło:
Redox report : communications in free radical research [Redox Rep] 2023 Dec; Vol. 28 (1), pp. 2279818. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Testis*
Antioxidants*/metabolism
Male ; Animals ; Mice ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Isothiocyanates/therapeutic use ; Isothiocyanates/metabolism ; Isothiocyanates/pharmacology
Czasopismo naukowe
Tytuł:
Heterogeneity of Phase II Enzyme Ligands on Controlling the Progression of Human Gastric Cancer Organoids as Stem Cell Therapy Model.
Autorzy:
Wu DC; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Ku CC; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Pan JB; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Wuputra K; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Yang YH; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Liu CJ; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Liu YC; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Kato K; Department of Infection Biology, Graduate School of Comprehensive Human Sciences, The University of Tsukuba, Tsukuba 305-8577, Japan.
Saito S; Saito Laboratory of Cell Technology, Yaita 239-1571, Japan.
Lin YC; School of Dentistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chong IW; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Division of Pulmonary and Critical Care Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Hsiao M; Genome Research Center, Academia Sinica, Nangan, Taipei 115, Taiwan.
Hu HM; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 801, Taiwan.
Kuo CH; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Department of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.
Kuo KK; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Lin CS; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Yokoyama KK; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Cell Therapy and Research Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 02; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Stomach Neoplasms*/drug therapy
Stomach Neoplasms*/metabolism
Humans ; Apoptosis ; Cell- and Tissue-Based Therapy ; Isothiocyanates/pharmacology ; Isothiocyanates/metabolism ; NF-E2-Related Factor 2/metabolism ; Organoids/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Sulfoxides/pharmacology
Czasopismo naukowe
Tytuł:
Anti-Proliferative Properties of the Novel Hybrid Drug Met-ITC, Composed of the Native Drug Metformin with the Addition of an Isothiocyanate H 2 S Donor Moiety, in Different Cancer Cell Lines.
Autorzy:
Citi V; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Barresi E; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.; Center for Instrument Sharing of the University of Pisa (CISUP), University of Pisa, Lungarno Pacinotti 43/44, 56126 Pisa, Italy.
Piragine E; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Spezzini J; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Testai L; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.; Center for Instrument Sharing of the University of Pisa (CISUP), University of Pisa, Lungarno Pacinotti 43/44, 56126 Pisa, Italy.; Interdepartmental Research Center 'Biology and Pathology of Ageing', University of Pisa, 56126 Pisa, Italy.
Da Settimo F; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.; Center for Instrument Sharing of the University of Pisa (CISUP), University of Pisa, Lungarno Pacinotti 43/44, 56126 Pisa, Italy.
Martelli A; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.; Center for Instrument Sharing of the University of Pisa (CISUP), University of Pisa, Lungarno Pacinotti 43/44, 56126 Pisa, Italy.; Interdepartmental Research Center 'Biology and Pathology of Ageing', University of Pisa, 56126 Pisa, Italy.
Taliani S; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.; Center for Instrument Sharing of the University of Pisa (CISUP), University of Pisa, Lungarno Pacinotti 43/44, 56126 Pisa, Italy.
Calderone V; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.; Center for Instrument Sharing of the University of Pisa (CISUP), University of Pisa, Lungarno Pacinotti 43/44, 56126 Pisa, Italy.; Interdepartmental Research Center 'Biology and Pathology of Ageing', University of Pisa, 56126 Pisa, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 09; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Metformin*/pharmacology
Diabetes Mellitus, Type 2*
Neoplasms*/drug therapy
Hydrogen Sulfide*/pharmacology
Hydrogen Sulfide*/metabolism
Humans ; Phosphatidylinositol 3-Kinases ; Cell Line ; Isothiocyanates/pharmacology
Czasopismo naukowe
Tytuł:
The Effect of Moringa Isothiocyanate-1 on Renal Damage in Diabetic Nephropathy.
Autorzy:
Chen L
Fan D
Guo F
Deng J
Fu L; Department of Pathology, Huzhou Central Hospital and Affiliated Central Hospital Huzhou University, 313000 Huzhou, Zhejiang, China. .
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Źródło:
Iranian journal of kidney diseases [Iran J Kidney Dis] 2023 Sep; Vol. 17 (5), pp. 245-254.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Diabetic Nephropathies*/drug therapy
Diabetic Nephropathies*/etiology
Diabetic Nephropathies*/metabolism
Moringa*/metabolism
Diabetes Mellitus*
Mice ; Animals ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/pharmacology ; NF-E2-Related Factor 2/therapeutic use ; Kidney ; Oxidative Stress ; Glutathione ; Isothiocyanates/pharmacology ; Isothiocyanates/metabolism ; Isothiocyanates/therapeutic use
Czasopismo naukowe
Tytuł:
Wasabi Component 6-(Methylsulfinyl)hexly Isothiocyanate and Derivatives Improve the Survival of Skin Allografts.
Autorzy:
Huang TS; Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.; Department of Surgery, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Ko CJ; Department Medical Research, MacKay Memorial Hospital, New Taipei City 251020, Taiwan.
Lin JC; Department of Surgery, MacKay Memorial Hospital, Taipei 10449, Taiwan.; MacKay Junior College of Medicine, Nursing, and Management, New Taipei City 11260, Taiwan.; Department of Surgery, MacKay Medical College, New Taipei City 25245, Taiwan.
Hsu ML; Department Medical Research, MacKay Memorial Hospital, New Taipei City 251020, Taiwan.
Ko CC; Department Medical Research, MacKay Memorial Hospital, New Taipei City 251020, Taiwan.
Chi CW; Department Medical Research, MacKay Memorial Hospital, New Taipei City 251020, Taiwan.
Tsai TH; Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Chen YJ; Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.; Department Medical Research, MacKay Memorial Hospital, New Taipei City 251020, Taiwan.; Department of Radiation Oncology, MacKay Memorial Hospital, Taipei 104217, Taiwan.; Department of Artificial Intelligence and Medical Application, MacKay Junior College of Medicine, Nursing and Management, Taipei 112021, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung 404332, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 30; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 30.
Typ publikacji:
Journal Article
MeSH Terms:
Interferon-gamma*
Isothiocyanates*/pharmacology
Allografts ; Animals ; Dendritic Cells ; Graft Survival ; Humans ; Rats
Czasopismo naukowe
Tytuł:
Protective Effect of Allyl Isothiocyanate in an Experimentally Induced Rat Model for Dry Eye Syndrome.
Autorzy:
Muz OE; Department of Ophthalmology, Yunus Emre State Hospital, Eskisehir, Turkey.
Orhan C; Department of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey.
Tuzcu M; Department of Biology, Faculty of Science, Firat University, Elazig, Turkey.
Er B; Department of Biology, Faculty of Science, Firat University, Elazig, Turkey.
Morde AA; Research & Development, OmniActive Health Technologies, Mumbai, India.
Padigaru M; Research & Development, OmniActive Health Technologies, Mumbai, India.
Ozercan IH; Department of Pathology, Faculty of Medicine, Firat University, Elazig, Turkey.
Sahin K; Department of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey.
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Źródło:
Current eye research [Curr Eye Res] 2022 May; Vol. 47 (5), pp. 704-714. Date of Electronic Publication: 2022 Mar 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dry Eye Syndromes*/pathology
Isothiocyanates*/therapeutic use
Animals ; Antioxidants/pharmacology ; Benzalkonium Compounds/toxicity ; Inflammation/metabolism ; Rats ; Rats, Wistar ; Tears/metabolism
Czasopismo naukowe
Tytuł:
Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity.
Autorzy:
Janczewski Ł; Faculty of Chemistry, Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Mar 07; Vol. 27 (5). Date of Electronic Publication: 2022 Mar 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Isothiocyanates*
Sulfoxides*
Czasopismo naukowe
Tytuł:
The Anti-Tumoral Potential of Phosphonate Analog of Sulforaphane in Zebrafish Xenograft Model.
Autorzy:
Rudzinska-Radecka M; Foundation of Research and Science Development, Rydygiera 8, 01-793 Warsaw, Poland.; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Janczewski Ł; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Gajda A; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Godlewska M; Department of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.
Chmielewska-Krzesinska M; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Wasowicz K; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
Podlasz P; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.
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Źródło:
Cells [Cells] 2021 Nov 18; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Xenograft Model Antitumor Assays*
Antineoplastic Agents/*pharmacology
Isothiocyanates/*pharmacology
Organophosphonates/*pharmacology
Sulfoxides/*pharmacology
Zebrafish/*physiology
Animals ; Cell Line, Tumor ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/metabolism ; Humans ; Isothiocyanates/chemical synthesis ; Isothiocyanates/chemistry ; Microwaves ; Organophosphonates/chemical synthesis ; Organophosphonates/chemistry ; Signal Transduction/drug effects ; Sulfoxides/chemical synthesis ; Sulfoxides/chemistry ; Zebrafish/embryology
Czasopismo naukowe

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