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Tytuł:
Obesity Treatments to Improve Type 1 Diabetes (OTID): a randomized controlled trial of the combination of glucagon-like peptide 1 analogues and sodium-glucose cotransporter 2 inhibitors-protocol for Obesity Treatments to Improve Type 1 Diabetes (the OTID trial).
Autorzy:
Al-Ozairi E; Dasman Diabetes Institute, Kuwait City, Kuwait.
Narula K; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK. .
Miras AD; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; School of Medicine, Ulster University, Coleraine, UK.
Taghadom E; Dasman Diabetes Institute, Kuwait City, Kuwait.; Amiri Hospital, Ministry of Health, Kuwait City, Kuwait.
Samad AE; Dasman Diabetes Institute, Kuwait City, Kuwait.
Al Kandari J; Dasman Diabetes Institute, Kuwait City, Kuwait.; Amiri Hospital, Ministry of Health, Kuwait City, Kuwait.
Alyosef A; Amiri Hospital, Ministry of Health, Kuwait City, Kuwait.
Mashankar A; Dasman Diabetes Institute, Kuwait City, Kuwait.
Al-Najim W; School of Medicine, Ulster University, Coleraine, UK.; Diabetes Complications Research Centre, Conway Institute, University College of Dublin, Dublin, Ireland.
le Roux CW; School of Medicine, Ulster University, Coleraine, UK.; Diabetes Complications Research Centre, Conway Institute, University College of Dublin, Dublin, Ireland.
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Źródło:
Trials [Trials] 2024 Feb 16; Vol. 25 (1), pp. 129. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 1*/diagnosis
Diabetes Mellitus, Type 1*/drug therapy
Diabetes Mellitus, Type 1*/complications
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Renal Insufficiency, Chronic*/diagnosis
Renal Insufficiency, Chronic*/drug therapy
Renal Insufficiency, Chronic*/complications
Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Hypoglycemic Agents/adverse effects ; Glucagon-Like Peptide 1 ; Obesity/complications ; Obesity/diagnosis ; Obesity/drug therapy ; Glucose ; Sodium ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
A Federated Database for Obesity Research: An IMI-SOPHIA Study.
Autorzy:
Delfin C; Novo Nordisk A/S, 2860 Søborg, Denmark.
Dragan I; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Kuznetsov D; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Tajes JF; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre (CRC), Lund University, Jan Waldenströmsgata 35, SE-20502 Malmö, Sweden.
Smit F; Maastricht Center for Systems Biology, Faculty of Science and Engineering, Maastricht University, Paul Henri Spaaklaan 1, 6229 EN Maastricht, The Netherlands.
Coral DE; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre (CRC), Lund University, Jan Waldenströmsgata 35, SE-20502 Malmö, Sweden.
Farzaneh A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Haugg A; Global Biostatistics & Data Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88400 Biberach, Germany.
Hungele A; Institute of Epidemiology and Medical Biometry, CAQM, University of Ulm, 89081 Ulm, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
Niknejad A; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Hall C; Division of Population Health and Genomics, Ninewells Hospital and School of Medicine, University of Dundee, Dundee DD1 4HN, UK.
Jacobs D; Nederlandse Obesitas Kliniek, Huis Ter Heide, 3712 BA Utrecht, The Netherlands.
Marek D; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Fraser DP; University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
Thuillier D; Univ Lille, Inserm, CHU Lille, Pasteur Institute Lille, U1190 Translational Research for Diabetes, European Genomic Institute of Diabetes, 59000 Lille, France.
Ahmadizar F; Data Science and Biostatistics Department, Julius Global Health, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Mehl F; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Pattou F; Univ Lille, Inserm, CHU Lille, Pasteur Institute Lille, U1190 Translational Research for Diabetes, European Genomic Institute of Diabetes, 59000 Lille, France.
Burdet F; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Hawkes G; University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
Arts ICW; Maastricht Center for Systems Biology, Faculty of Science and Engineering, Maastricht University, Paul Henri Spaaklaan 1, 6229 EN Maastricht, The Netherlands.
Blanch J; Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 08007 Barcelona, Spain.; ISV-Girona Research Group, Research Unit in Primary Care, Primary Care Services, Catalan Institute of Health (ICS), 08908 Barcelona, Spain.
Van Soest J; Brightlands Institute for Smart Society (BISS), Faculty of Science and Engineering, Maastricht University, 6229 EN Maastricht, The Netherlands.; Department of Radiation Oncology (Maastro), GROW-School for Oncology and Reproduction, Maastricht University Medical Center, 6229 EN Maastricht, The Netherlands.
Fernández-Real JM; Nutrition, Eumetabolism and Health Group, Institut d'Investigació Biomèdica de Girona (IDIBGI-CERCA), Av. França 30, 17007 Girona, Spain.; Department of Medical Sciences, School of Medicine, University of Girona, 17003 Girona, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital, Av. França, s/n, 17007 Girona, Spain.
Boehl J; Global Biostatistics & Data Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88400 Biberach, Germany.
Fink K; Institute of Epidemiology and Medical Biometry, CAQM, University of Ulm, 89081 Ulm, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
van Greevenbroek MMJ; Department of Internal Medicine and CARIM School of Cardiovascular Diseases, Maastricht University, 6229 EN Maastricht, The Netherlands.
Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Minten M; Maastricht Center for Systems Biology, Faculty of Science and Engineering, Maastricht University, Paul Henri Spaaklaan 1, 6229 EN Maastricht, The Netherlands.
Prinz N; Institute of Epidemiology and Medical Biometry, CAQM, University of Ulm, 89081 Ulm, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
Ipsen N; Novo Nordisk A/S, 2860 Søborg, Denmark.
Franks PW; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre (CRC), Lund University, Jan Waldenströmsgata 35, SE-20502 Malmö, Sweden.
Ramos R; Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 08007 Barcelona, Spain.; Department of Medical Sciences, School of Medicine, University of Girona, 17003 Girona, Spain.; Department of Medical Informatics, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.; Research in Vascular Health Group, Institut d'Investigació Biomèdica de Girona (IDIBGI-CERCA), Parc Hospitalari Martí i Julià, Edifici M2, 17190 Salt, Spain.
Holl RW; Institute of Epidemiology and Medical Biometry, CAQM, University of Ulm, 89081 Ulm, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
Horban S; Division of Population Health and Genomics, Ninewells Hospital and School of Medicine, University of Dundee, Dundee DD1 4HN, UK.
Duarte-Salles T; Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), 08007 Barcelona, Spain.; Department of Medical Informatics, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
Tran VDT; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Raverdy V; Univ Lille, Inserm, CHU Lille, Pasteur Institute Lille, U1190 Translational Research for Diabetes, European Genomic Institute of Diabetes, 59000 Lille, France.
Leal Y; Nutrition, Eumetabolism and Health Group, Institut d'Investigació Biomèdica de Girona (IDIBGI-CERCA), Av. França 30, 17007 Girona, Spain.; Department of Medical Sciences, School of Medicine, University of Girona, 17003 Girona, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital, Av. França, s/n, 17007 Girona, Spain.
Lenart A; Novo Nordisk A/S, 2860 Søborg, Denmark.
Pearson E; Division of Population Health and Genomics, Ninewells Hospital and School of Medicine, University of Dundee, Dundee DD1 4HN, UK.
Sparsø T; Novo Nordisk A/S, 2860 Søborg, Denmark.
Giordano GN; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre (CRC), Lund University, Jan Waldenströmsgata 35, SE-20502 Malmö, Sweden.
Ioannidis V; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
Soh K; Novo Nordisk A/S, 2860 Søborg, Denmark.
Frayling TM; University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, 1 Rue Michel-Servet, CH-1211 Geneva, Switzerland.
Le Roux CW; Diabetes Complications Research Centre, University College Dublin, D04 V1W8 Dublin, Ireland.
Ibberson M; Vital-IT Group, SIB Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
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Źródło:
Life (Basel, Switzerland) [Life (Basel)] 2024 Feb 16; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Reduction of prevalence of patients meeting the criteria for metabolic syndrome with tirzepatide: a post hoc analysis from the SURPASS Clinical Trial Program.
Autorzy:
Nicholls SJ; Victorian Heart Institute, Monash University, Clayton, VIC, Australia.
Tofé S; Department of Endocrinology and Nutrition, University Hospital Son Espases, Palma, Spain.
le Roux CW; Diabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, Dublin, Ireland.; Diabetes Research Centre, Ulster University, Coleraine, UK.
D'Alessio DA; Division of Endocrinology, Department of Medicine, Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
Wiese RJ; Eli Lilly and Company, Indianapolis, IN, USA.
Pavo I; Eli Lilly Regional Operations GmbH, Vienna, Austria.
Brown K; Eli Lilly and Company, Indianapolis, IN, USA.
Weerakkody GJ; Eli Lilly and Company, Indianapolis, IN, USA.
Zeytinoglu M; Eli Lilly and Company, Indianapolis, IN, USA.
Romera IC; Eli Lilly and Company, Avda. de La Industria 30, 28108, Alcobendas, Madrid, Spain. romera_.
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Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2024 Feb 10; Vol. 23 (1), pp. 63. Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Metabolic Syndrome*/diagnosis
Metabolic Syndrome*/drug therapy
Metabolic Syndrome*/epidemiology
Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/epidemiology
Glucagon-Like Peptide-2 Receptor*
Adult ; Humans ; Prevalence ; Insulin Glargine ; Gastric Inhibitory Polypeptide ; Obesity ; Body Weight ; Hypoglycemic Agents/adverse effects
Czasopismo naukowe
Tytuł:
Impact of Bariatric Surgery on Subtilisin/Kexin Type 9 (PCSK9) Gene Expression and Inflammation in the Adipose Tissue of Obese Diabetic Rats.
Autorzy:
Heald AH; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK.
Fachim HA; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK.
Bashir B; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK.
Garside B; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK.
Adam S; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; The Christie Hospital NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Iqbal Z; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK.
Syed AA; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK.
Donn R; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Le Roux CW; Diabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Abdelaal M; Diabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
White J; Diabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Soran H; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 30; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Bariatric Surgery*
Diabetes Mellitus, Experimental*/genetics
Diabetes Mellitus, Experimental*/surgery
Animals ; Rats ; Adipose Tissue/metabolism ; Gene Expression ; Inflammation/genetics ; Obesity/genetics ; Obesity/surgery ; Proprotein Convertase 9/genetics ; Proprotein Convertases/genetics ; Rats, Sprague-Dawley ; Rats, Zucker ; Receptors, LDL/genetics ; Receptors, LDL/metabolism ; Serine Endopeptidases/metabolism ; Subtilisin/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł:
Obesity Characteristics Are Poor Predictors of Genetic Mutations Associated with Obesity.
Autorzy:
Al-Humadi AW; Diabetes Complications Research Centre, Conway Institute, University College Dublin, D04V1W8 Dublin, Ireland.; Department of Dentistry, Hilla University College, Babylon 510001, Iraq.
Alabduljabbar K; Diabetes Complications Research Centre, Conway Institute, University College Dublin, D04V1W8 Dublin, Ireland.; Department of Family Medicine and Polyclinics, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia.
Alsaqaaby MS; Diabetes Complications Research Centre, Conway Institute, University College Dublin, D04V1W8 Dublin, Ireland.; Obesity, Endocrine and Metabolism Centre, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
Talaee H; Diabetes Complications Research Centre, Conway Institute, University College Dublin, D04V1W8 Dublin, Ireland.
le Roux CW; Diabetes Complications Research Centre, Conway Institute, University College Dublin, D04V1W8 Dublin, Ireland.
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Źródło:
Journal of clinical medicine [J Clin Med] 2023 Oct 07; Vol. 12 (19). Date of Electronic Publication: 2023 Oct 07.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Understanding the risk of developing weight-related complications associated with different body mass index categories: a systematic review.
Autorzy:
Taieb AB; Wickenstones Ltd., Oxford, UK.
Roberts E; Wickenstones Ltd., Oxford, UK.
Luckevich M; Novo Nordisk Canada Inc., Mississauga, ON, Canada.
Larsen S; Novo Nordisk A/S, Søborg, Denmark. .
le Roux CW; Diabetes Complications Research Centre, Conway Institute, University College, Dublin, Ireland.
de Freitas PG; Wickenstones Ltd., Oxford, UK.
Wolfert D; Wickenstones Ltd., Oxford, UK.
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Źródło:
Diabetology & metabolic syndrome [Diabetol Metab Syndr] 2022 Dec 07; Vol. 14 (1), pp. 186. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Tytuł:
Erythritol and xylitol differentially impact brain networks involved in appetite regulation in healthy volunteers.
Autorzy:
Meyer-Gerspach AC; St. Clara Research Ltd at St. Clara Hospital, Basel, Switzerland.; Department of Medicine, University of Basel, Basel, Switzerland.
Wingrove JO; Centre for Obesity Research, University College London, London, UK.
Beglinger C; St. Clara Research Ltd at St. Clara Hospital, Basel, Switzerland.
Rehfeld JF; Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Le Roux CW; Diabetes Complications Research Centre, Conway Institute University College Dublin, Dublin, Ireland.
Peterli R; Department of Medicine, University of Basel, Basel, Switzerland.; Clarunis, Department of Visceral Surgery, University Centre for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.
Dupont P; Department of Neurosciences, Laboratory for Cognitive Neurology, KU Leuven, Leuven, Belgium.
O'Daly O; Centre for Neuroimaging Sciences, King's College London's Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Van Oudenhove L; Laboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism & Ageing, KU Leuven, Leuven, Belgium.; Cognitive and Affective Neuroscience Lab (CANlab), Department of Psychological & Brain Sciences, Dartmouth College, Hanover, NH, USA.
Wölnerhanssen BK; St. Clara Research Ltd at St. Clara Hospital, Basel, Switzerland.; Department of Medicine, University of Basel, Basel, Switzerland.
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Źródło:
Nutritional neuroscience [Nutr Neurosci] 2022 Nov; Vol. 25 (11), pp. 2344-2358. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Xylitol*/pharmacology
Insulins*
Humans ; Erythritol/pharmacology ; Appetite Regulation ; Healthy Volunteers ; Sweetening Agents ; Glucose ; Appetite ; Brain ; Water
Czasopismo naukowe
Tytuł:
Differential effects of RYGB surgery and best medical treatment for obesity-diabetes on intestinal and islet adaptations in obese-diabetic ZDSD rats.
Autorzy:
Sridhar A; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.
Khan D; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.
Abdelaal M; Diabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Elliott JA; Department of Surgery, Trinity Centre for Health Sciences and St. James's Hospital, Dublin, Ireland.
Naughton V; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.
Flatt PR; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.
Le Roux CW; Diabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Docherty NG; Diabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Moffett CR; Biomedical Sciences Research Institute, School of Biomedical Sciences, Ulster University, Coleraine, Northern Ireland, United Kingdom.
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Źródło:
PloS one [PLoS One] 2022 Sep 22; Vol. 17 (9), pp. e0274788. Date of Electronic Publication: 2022 Sep 22 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus*
Fenofibrate*
Gastric Bypass*
Metformin*
Animals ; Blood Glucose/metabolism ; Glucagon/metabolism ; Glucagon-Like Peptide 1/metabolism ; Insulin/metabolism ; Liraglutide/pharmacology ; Liraglutide/therapeutic use ; Male ; Obesity/surgery ; Ramipril ; Rats ; Rats, Sprague-Dawley ; Rats, Zucker ; Rosuvastatin Calcium ; Somatostatin/therapeutic use
Czasopismo naukowe
Tytuł:
Ciliary neurotrophic factor is increased in the plasma of patients with obesity and its levels correlate with diabetes and inflammation indices.
Autorzy:
Perugini J; Department of Experimental and Clinical Medicine, School of Medicine, Marche Polytechnic University, Via Tronto 10/A, 60020, Ancona, Italy.
Di Mercurio E; Department of Experimental and Clinical Medicine, School of Medicine, Marche Polytechnic University, Via Tronto 10/A, 60020, Ancona, Italy.
Giuliani A; Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Sabbatinelli J; Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.; Laboratory Medicine Unit, United Hospitals, Ancona, Italy.
Bonfigli AR; Scientific Direction, IRCCS INRCA, Ancona, Italy.
Tortato E; Diabetology Unit, IRCCS INRCA, Ancona, Italy.
Severi I; Department of Experimental and Clinical Medicine, School of Medicine, Marche Polytechnic University, Via Tronto 10/A, 60020, Ancona, Italy.
Cinti S; Department of Experimental and Clinical Medicine, School of Medicine, Marche Polytechnic University, Via Tronto 10/A, 60020, Ancona, Italy.; Center of Obesity, Marche Polytechnic University-United Hospitals, Ancona, Italy.
Olivieri F; Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.; Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, Ancona, Italy.
le Roux CW; Diabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, Dublin, Ireland.
Gesuita R; Center of Epidemiology and Biostatistics, Marche Polytechnic University, Ancona, Italy.
Giordano A; Department of Experimental and Clinical Medicine, School of Medicine, Marche Polytechnic University, Via Tronto 10/A, 60020, Ancona, Italy. .; Center of Obesity, Marche Polytechnic University-United Hospitals, Ancona, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2022 May 18; Vol. 12 (1), pp. 8331. Date of Electronic Publication: 2022 May 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ciliary Neurotrophic Factor Receptor alpha Subunit*/blood
Diabetes Mellitus*/blood
Obesity*/blood
Case-Control Studies ; Female ; Humans ; Inflammation/blood ; Male
Czasopismo naukowe
Tytuł:
Amylin as a Future Obesity Treatment.
Autorzy:
Dehestani B; Department of Metabolic Medicine, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin, Ireland.
Stratford NR; Department of Metabolic Medicine, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin, Ireland.
le Roux CW; Department of Metabolic Medicine, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin, Ireland.
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Źródło:
Journal of obesity & metabolic syndrome [J Obes Metab Syndr] 2021 Dec 30; Vol. 30 (4), pp. 320-325.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Tytuł:
Weight loss with bariatric surgery or behaviour modification and the impact on female obesity-related urine incontinence: A comprehensive systematic review and meta-analysis.
Autorzy:
Sheridan W; Faculty of Life Sciences and Medicine, School of Life Course Sciences, King's College London, London, UK.
Da Silva AS; Department of Urogynaecology, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
Leca BM; University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Ostarijas E; Institute for Translational Medicine, University of Pecs Medical School, Pécs, Hungary.
Patel AG; Department of Minimal Access Surgery, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
Aylwin SJ; Department of Endocrinology ASO/EASO COM, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
Vincent RP; Faculty of Life Sciences and Medicine, School of Life Course Sciences, King's College London, London, UK.; Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
Panagiotopoulos S; Department of Minimal Access Surgery, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
El-Hasani S; Minimal Access and Bariatric Unit, Princess Royal University Hospital, King's College Hospital NHS Foundation Trust, Orpington, UK.
le Roux CW; Diabetes Complication Research Centre, School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Belfield, Ireland.
Miras AD; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Cardozo L; Department of Urogynaecology, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
Dimitriadis GK; Faculty of Life Sciences and Medicine, School of Life Course Sciences, King's College London, London, UK.; Department of Endocrinology ASO/EASO COM, King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
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Źródło:
Clinical obesity [Clin Obes] 2021 Aug; Vol. 11 (4), pp. e12450. Date of Electronic Publication: 2021 May 06.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Bariatric Surgery*
Obesity*/complications
Obesity*/epidemiology
Obesity*/surgery
Urinary Incontinence*/epidemiology
Urinary Incontinence*/etiology
Weight Loss*
Behavior Therapy ; Female ; Humans ; Quality of Life
Czasopismo naukowe
Tytuł:
The role of staging laparoscopy in complex bariatric surgery.
Autorzy:
Sudlow AC; Department of Upper GI and Bariatric/Metabolic Surgery, North Bristol NHS Trust, Southmead Hospital, Bristol, UK.
le Roux CW; Department of Experimental Pathology, University College Dublin, Dublin, Ireland.
Hardwick R; Department of Upper GI Surgery, Addenbrookes Hospital, Cambridge, UK.
Pournaras DJ; Department of Upper GI and Bariatric/Metabolic Surgery, North Bristol NHS Trust, Southmead Hospital, Bristol, UK.
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Źródło:
Clinical obesity [Clin Obes] 2021 Aug; Vol. 11 (4), pp. e12460. Date of Electronic Publication: 2021 May 03.
Typ publikacji:
Case Reports
MeSH Terms:
Bariatric Surgery*
Gastric Bypass*
Laparoscopy*
Humans ; Obesity, Morbid/surgery ; Reoperation ; Retrospective Studies ; Treatment Outcome
Raport
Tytuł:
Exaggerated postprandial GLP-1 secretion following esophagectomy is not associated with gastric emptying and intestinal transit.
Autorzy:
Murphy CF; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.; National Oesophageal and Gastric Centre, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin 8, Ireland.
Elliott JA; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.; National Oesophageal and Gastric Centre, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin 8, Ireland.
Docherty NG; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.
Mohamed AA; Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Vincent RP; Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK.
Ravi N; National Oesophageal and Gastric Centre, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin 8, Ireland.
Reynolds JV; National Oesophageal and Gastric Centre, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin 8, Ireland.
le Roux CW; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland.
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Źródło:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus [Dis Esophagus] 2021 Jul 12; Vol. 34 (7).
Typ publikacji:
Journal Article
MeSH Terms:
Esophagectomy*
Gastric Emptying*
Cross-Sectional Studies ; Glucagon-Like Peptide 1 ; Humans ; Male ; Postprandial Period
Czasopismo naukowe
Tytuł:
The lived experience of people with obesity: study protocol for a systematic review and synthesis of qualitative studies.
Autorzy:
Farrell E; School of Education, University College Dublin, Belfield, Dublin 4, Ireland. .
Bustillo M; University College Dublin Library, Dublin, Ireland.
le Roux CW; Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland.
Nadglowski J; Obesity Action Coalition, Tampa, USA.
Hollmann E; School of Education, University College Dublin, Belfield, Dublin 4, Ireland.
McGillicuddy D; School of Education, University College Dublin, Belfield, Dublin 4, Ireland.
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Źródło:
Systematic reviews [Syst Rev] 2021 Jun 21; Vol. 10 (1), pp. 181. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Health Personnel*
Quality of Life*
Adult ; Delivery of Health Care ; Humans ; Obesity ; Qualitative Research ; Review Literature as Topic ; Systematic Reviews as Topic
Czasopismo naukowe
Tytuł:
Clinical Impact of Liraglutide as a Treatment of Obesity
Autorzy:
Alruwaili H
Dehestani B
le Roux CW
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Temat:
liraglutide
obesity
weight loss
glp-1 analogue
Therapeutics. Pharmacology
RM1-950
Źródło:
Clinical Pharmacology: Advances and Applications, Vol Volume 13, Pp 53-60 (2021)
Opis pliku:
electronic resource
Relacje:
https://www.dovepress.com/clinical-impact-of-liraglutide-as-a-treatment-of-obesity-peer-reviewed-article-CPAA; https://doaj.org/toc/1179-1438
Dostęp URL:
https://doaj.org/article/a6dd020fdd0549d2a9e2f4e412d332e9  Link otwiera się w nowym oknie
Czasopismo naukowe
Tytuł:
Early experience with a nutrition and survivorship clinic in esophageal cancer.
Autorzy:
Murphy CF; National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.; Diabetes Complications Research Centre, Conway Institute for Biomedical Science, University College Dublin, Dublin, Ireland.
Fanning M; Department of Clinical Nutrition, St James's Hospital, Dublin, Ireland.
Raftery N; National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.
Elliott JA; National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.; Diabetes Complications Research Centre, Conway Institute for Biomedical Science, University College Dublin, Dublin, Ireland.
Docherty NG; Diabetes Complications Research Centre, Conway Institute for Biomedical Science, University College Dublin, Dublin, Ireland.
Donohoe CL; National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.
Ravi N; National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.
le Roux CW; Diabetes Complications Research Centre, Conway Institute for Biomedical Science, University College Dublin, Dublin, Ireland.
Reynolds JV; National Center for Esophageal and Gastric Cancer, Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.
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Źródło:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus [Dis Esophagus] 2021 Feb 10; Vol. 34 (2).
Typ publikacji:
Journal Article
MeSH Terms:
Esophageal Neoplasms*/complications
Esophageal Neoplasms*/mortality
Esophageal Neoplasms*/pathology
Esophageal Neoplasms*/surgery
Esophagectomy*/mortality
Quality of Life*
Nutrition Disorders/*therapy
Aged ; Female ; Humans ; Male ; Middle Aged ; Nutrition Disorders/etiology ; Nutritional Status ; Survivorship
Czasopismo naukowe
Tytuł:
Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses.
Autorzy:
McGlone ER; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Carey I; Population Health Research Institute, St George's Hospital, University of London, London, United Kingdom.
Veličković V; Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT, Hall in Tirol, Austria.
Chana P; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Mahawar K; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Batterham RL; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.; UCL Centre for Obesity Research, Division of Medicine, Rayne Building, University College London, London, United Kingdom.; National Institute of Health Research, UCLH Biomedical Research Centre, London, United Kingdom.
Hopkins J; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Walton P; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Kinsman R; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Byrne J; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Somers S; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Kerrigan D; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Menon V; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Borg C; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Ahmed A; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Sgromo B; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Cheruvu C; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Bano G; St George's Hospital, London, United Kingdom.
Leonard C; Medtronic Ltd, Croxley Green Business Park, Hatters Lane, Watford, United Kingdom.
Thom H; Department of Population Health Sciences, Bristol Medical School, University of Bristol, United Kingdom.
le Roux CW; Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland.
Reddy M; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Welbourn R; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Small P; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.
Khan OA; National Bariatric Surgical Registry (NBSR)/British Obesity and Metabolic Surgical Society (BOMSS), Royal College of Surgeons of England, London, United Kingdom.; Population Health Research Institute, St George's Hospital, University of London, London, United Kingdom.; St George's Hospital, London, United Kingdom.
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Źródło:
PLoS medicine [PLoS Med] 2020 Dec 07; Vol. 17 (12), pp. e1003228. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Health Care Costs*
Bariatric Surgery/*economics
Diabetes Mellitus, Type 2/*drug therapy
Diabetes Mellitus, Type 2/*economics
Hypoglycemic Agents/*administration & dosage
Hypoglycemic Agents/*economics
Insulin/*administration & dosage
Insulin/*economics
Obesity/*economics
Obesity/*surgery
Adult ; Cost Savings ; Cost-Benefit Analysis ; Databases, Factual ; Diabetes Mellitus, Type 2/diagnosis ; Drug Costs ; Female ; Gastrectomy/economics ; Gastric Bypass/economics ; Humans ; Male ; Middle Aged ; Models, Economic ; Obesity/diagnosis ; Quality of Life ; Quality-Adjusted Life Years ; Registries ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł:
"I am terrified of something happening to me" The lived experience of people with obesity during the COVID-19 pandemic.
Autorzy:
Grannell A; Diabetes Complications Research Centre, Conway Institute, University College Dublin, Dublin, Ireland.
le Roux CW; Diabetes Complications Research Centre, Conway Institute, University College Dublin, Dublin, Ireland.
McGillicuddy D; School of Education, University College Dublin, Dublin, Ireland.
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Źródło:
Clinical obesity [Clin Obes] 2020 Dec; Vol. 10 (6), pp. e12406. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji:
Journal Article
MeSH Terms:
Health Knowledge, Attitudes, Practice*
Coronavirus Infections/*psychology
Obesity/*psychology
Pneumonia, Viral/*psychology
Adult ; Aged ; Anxiety ; Betacoronavirus ; COVID-19 ; Diet ; Exercise ; Fear ; Female ; Humans ; Interviews as Topic ; Male ; Mental Health ; Middle Aged ; Pandemics ; Qualitative Research ; Risk Factors ; SARS-CoV-2 ; Stress, Psychological
Czasopismo naukowe
Tytuł:
Obesity: A critical risk factor in the COVID-19 pandemic.
Autorzy:
Kwok S; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Adam S; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Department of Endocrinology, Christie NHS Foundation Trust, Manchester, UK.
Ho JH; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Iqbal Z; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Turkington P; Department of Respiratory Medicine, Salford Royal NHS Foundation Trust, Salford, UK.
Razvi S; Cardiovascular Research Centre, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
Le Roux CW; Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland.
Soran H; Cardiovascular Trials Unit, Manchester University NHS Foundation Trust, Manchester, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Syed AA; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation Trust, Salford, UK.
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Źródło:
Clinical obesity [Clin Obes] 2020 Dec; Vol. 10 (6), pp. e12403. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Coronavirus Infections/*complications
Obesity/*complications
Pneumonia, Viral/*complications
Betacoronavirus ; COVID-19 ; Comorbidity ; Endocrine System ; Hospitalization ; Humans ; Immune System ; Pandemics ; Respiratory System ; Risk Factors ; SARS-CoV-2 ; Thrombosis/complications ; Vulnerable Populations
Czasopismo naukowe
Tytuł:
Obesity is common in chronic kidney disease and associates with greater antihypertensive usage and proteinuria: evidence from a cross-sectional study in a tertiary nephrology centre.
Autorzy:
Martin WP; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, Dublin, Ireland.; Department of Nephrology, St. Vincent's University Hospital, Dublin, Ireland.
Bauer J; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, Dublin, Ireland.
Coleman J; Department of Nephrology, St. Vincent's University Hospital, Dublin, Ireland.
Dellatorre-Teixeira L; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, Dublin, Ireland.
Reeve JLV; Department of Clinical Chemistry, St. Vincent's University Hospital, Dublin, Ireland.
Twomey PJ; Department of Clinical Chemistry, St. Vincent's University Hospital, Dublin, Ireland.
Docherty NG; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, Dublin, Ireland.; Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
O'Riordan A; Department of Nephrology, St. Vincent's University Hospital, Dublin, Ireland.
Watson AJ; Department of Nephrology, St. Vincent's University Hospital, Dublin, Ireland.
le Roux CW; Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, Dublin, Ireland.; Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Division of Investigative Science, Imperial College London, London, UK.
Holian J; Department of Nephrology, St. Vincent's University Hospital, Dublin, Ireland.
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Źródło:
Clinical obesity [Clin Obes] 2020 Dec; Vol. 10 (6), pp. e12402. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji:
Journal Article
MeSH Terms:
Body Mass Index*
Antihypertensive Agents/*therapeutic use
Hypertension/*epidemiology
Obesity/*complications
Proteinuria/*epidemiology
Renal Insufficiency, Chronic/*complications
Biomarkers/blood ; Biomarkers/urine ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Female ; Glomerular Filtration Rate ; Humans ; Hypertension/complications ; Hypertension/drug therapy ; Hypoglycemic Agents/therapeutic use ; Male ; Medical Audit ; Middle Aged ; Nephrology/statistics & numerical data ; Obesity/blood ; Obesity/urine ; Proteinuria/etiology ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/urine ; Risk Factors ; Sex Factors ; Tertiary Care Centers
Czasopismo naukowe

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