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Wyszukujesz frazę ""mRNA"" wg kryterium: Temat


Tytuł:
mRNA Vaccine Nanoplatforms and Innate Immunity.
Autorzy:
Wei L; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
Dong C; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
Zhu W; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
Wang BZ; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
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Źródło:
Viruses [Viruses] 2024 Jan 14; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
mRNA Vaccines*
Pandemics*
Humans ; Immunity, Innate ; Adaptive Immunity ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation.
Autorzy:
Geng K; Department of Radiation Oncology, Biologic Therapeutics Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in Saint Louis, St. Louis, MO 63130-4899, USA.
Rice-Boucher PJ; Department of Radiation Oncology, Biologic Therapeutics Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in Saint Louis, St. Louis, MO 63130-4899, USA.
Kashentseva EA; Department of Radiation Oncology, Biologic Therapeutics Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Dmitriev IP; Department of Radiation Oncology, Biologic Therapeutics Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Lu ZH; Department of Radiation Oncology, Biologic Therapeutics Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Goedegebuure SP; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.; Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, MO 63110, USA.
Gillanders WE; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.; Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, MO 63110, USA.
Curiel DT; Department of Radiation Oncology, Biologic Therapeutics Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in Saint Louis, St. Louis, MO 63130-4899, USA.
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Źródło:
Viruses [Viruses] 2023 Nov 20; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Adenoviridae*/genetics
Genetic Vectors*/genetics
mRNA Vaccines*
CD4-Positive T-Lymphocytes ; CD8-Positive T-Lymphocytes ; Genetic Engineering
Czasopismo naukowe
Tytuł:
A Combinatorial Code for CPEB-Mediated c-myc Repression.
Autorzy:
Ogami K; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.; Division of Molecular Oncology, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Ogawa K; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Sanpei S; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Ichikawa F; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Udagawa T; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Hoshino SI; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
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Źródło:
Cells [Cells] 2023 Oct 06; Vol. 12 (19). Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
mRNA Cleavage and Polyadenylation Factors*/metabolism
Oocytes*/metabolism
RNA/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Transcription Factors/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Award honors pair for mRNA work key to COVID-19 vaccines.
Autorzy:
Offord C
Cohen J
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Źródło:
Science (New York, N.Y.) [Science] 2023 Oct 06; Vol. 382 (6666), pp. 22. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Wiadomości
MeSH Terms:
COVID-19*/prevention & control
COVID-19 Vaccines*
Nobel Prize*
mRNA Vaccines*
Humans ; Vaccination ; United States
Periodyk
Tytuł:
Mapping SARS-CoV-2 antigenic relationships and serological responses.
Autorzy:
Wilks SH; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
Mühlemann B; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany.
Shen X; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Türeli S; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
LeGresley EB; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
Netzl A; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
Caniza MA; Department of Global Pediatric Medicine, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.
Chacaltana-Huarcaya JN; Hospital Nacional Daniel A. Carrión, Callao, Bellavista, Peru.
Corman VM; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany.
Daniell X; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Datto MB; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Dawood FS; Centers for Disease Control and Prevention, Atlanta, GA, USA.
Denny TN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Drosten C; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany.
Fouchier RAM; Erasmus Medical Center, Rotterdam, Netherlands.
Garcia PJ; School of Public Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Halfmann PJ; Influenza Research Institute, Department of Pathobiological Science, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Jassem A; BC Centre for Disease Control, Vancouver, British Columbia, Canada.
Jeworowski LM; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
Jones TC; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Infection Research (DZIF), partner site Charité, 10117 Berlin, Germany.
Kawaoka Y; Influenza Research Institute, Department of Pathobiological Science, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Tokyo, Japan.
Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Cellular and Molecular Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
McDanal C; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Pajon R; Moderna, Inc., Cambridge, MA, USA.
Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Cellular and Molecular Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Global Health and Emerging Pathogen Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stockwell MS; Division of Child and Adolescent Health, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, and Department of Population and Family Health, Mailman School of Public Health, New York, NY, USA.
Tang H; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
van Bakel H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Veguilla V; Centers for Disease Control and Prevention, Atlanta, GA, USA.
Webby R; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.
Montefiori DC; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.
Smith DJ; Center for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Oct 06; Vol. 382 (6666), pp. eadj0070. Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Spike Glycoprotein, Coronavirus*/genetics
Spike Glycoprotein, Coronavirus*/immunology
Antigens, Viral*/genetics
Antigens, Viral*/immunology
mRNA Vaccines*/immunology
Humans ; Antibodies, Neutralizing/blood ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Cross Reactions ; Vaccination ; Amino Acid Substitution
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
An overview on mRNA-based vaccines to prevent monkeypox infection.
Autorzy:
Natami M; Department of Urology, Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Gorgzadeh A; Faculty of Pharmacy, Jondi Shapour University, Ahvaz, Iran.
Gholipour A; Free Researchers, Biotechnology and Nanobiotechnology, Babolsar, Iran.
Fatemi SN; Faculty of Veterinary, University of Tehran, Tehran, Iran.
Firouzeh N; Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Zokaei M; Department of Food Science and Technology, Faculty of Nutrition Science, Food Science and Technology/National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammed Ali SH; College of Dentistry, Al-Mustaqbal University, Babylon, 51001, Iraq.
Kheradjoo H; Laboratory Department, Buraimi Hospital, Buraimi, Oman.
Sedighi S; Medical Science of Mashhad, Mashhad, Iran.
Gholizadeh O; AZAD Researchers, Viro & biotche, Tehran, Iran. .
Kalavi S; Department of Clinical Pharmacy, Faculty of Pharmacy, Islamic Azad University of Medical Sciences, Tehran, Iran. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 01; Vol. 22 (1), pp. 86. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Smallpox Vaccine*
Smallpox*
Mpox (monkeypox)*/prevention & control
United States ; Humans ; mRNA Vaccines ; COVID-19 Vaccines ; Antigens, Viral
Czasopismo naukowe
Tytuł:
Safety, Immunogenicity, and Mechanism of a Rotavirus mRNA-LNP Vaccine in Mice.
Autorzy:
Lu C; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Li Y; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Chen R; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Hu X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Leng Q; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Song X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Lin X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Ye J; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Wang J; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Li J; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Yao L; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Tang X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Kuang X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Zhang G; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Sun M; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Zhou Y; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Li H; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
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Źródło:
Viruses [Viruses] 2024 Jan 31; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Rotavirus*/genetics
Rotavirus Vaccines*/genetics
Rotavirus Infections*
Child ; Animals ; Mice ; Humans ; Child, Preschool ; mRNA Vaccines ; RNA, Messenger/genetics ; CD8-Positive T-Lymphocytes ; Leukocytes, Mononuclear ; Antibodies, Viral ; Capsid Proteins/genetics ; Adjuvants, Immunologic ; Vaccines, Attenuated ; Immunoglobulin G
Czasopismo naukowe
Tytuł:
mRNA-based precision targeting of neoantigens and tumor-associated antigens in malignant brain tumors.
Autorzy:
Trivedi V; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Yang C; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Klippel K; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Yegorov O; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
von Roemeling C; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Hoang-Minh L; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Fenton G; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Ogando-Rivas E; Boston Medical Center, Boston, MA, USA.
Castillo P; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Moore G; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Long-James K; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Dyson K; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Doonan B; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Flores C; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Mitchell DA; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA. .
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Źródło:
Genome medicine [Genome Med] 2024 Jan 25; Vol. 16 (1), pp. 17. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Medulloblastoma*
Cancer Vaccines*/genetics
Cerebellar Neoplasms*
Humans ; Animals ; Mice ; mRNA Vaccines ; Antigens, Neoplasm/genetics ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Novel Lipid Nanoparticles Stable and Efficient for mRNA Transfection to Antigen-Presenting Cells.
Autorzy:
Choi KC; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Lee DH; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Lee JW; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Lee JS; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Lee YK; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Choi MJ; Division of Hematology/Oncology, Brown University and Rhode Island Hospital, Providence, RI 02903, USA.
Jeong HY; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Kim MW; Division of Breast Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Lee CG; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
Park YS; Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Nanoparticles*/chemistry
Vaccines*
Liposomes*
Animals ; Mice ; RNA, Messenger/chemistry ; mRNA Vaccines ; Transfection ; Antigen-Presenting Cells
Czasopismo naukowe
Tytuł:
Engineered EVs with pathogen proteins: promising vaccine alternatives to LNP-mRNA vaccines.
Autorzy:
Zhang B; Institute of Molecular and Cellular Biology, A*STAR, 8A Biomedical Grove, Singapore, 138648, Singapore.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore, 688207, Singapore.
Sim WK; Institute of Molecular and Cellular Biology, A*STAR, 8A Biomedical Grove, Singapore, 138648, Singapore.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore, 688207, Singapore.
Shen TL; Department of Plant Pathology and Microbiology, National Taiwan University, Taipei, 10617, Taiwan.; Center for Biotehnology, National Taiwan University, Taipei, 10617, Taiwan.
Lim SK; Institute of Molecular and Cellular Biology, A*STAR, 8A Biomedical Grove, Singapore, 138648, Singapore. lim_sai_.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore, 688207, Singapore. lim_sai_.; Department of Surgery, YLL School of Medicine, National University of Singapore (NUS), Lower Kent Ridge Road, Singapore, 119074, Singapore. lim_sai_.
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Źródło:
Journal of biomedical science [J Biomed Sci] 2024 Jan 17; Vol. 31 (1), pp. 9. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mesenchymal Stem Cells*/metabolism
Extracellular Vesicles*/metabolism
Exosomes*/genetics
Vaccines*/genetics
mRNA Vaccines
Czasopismo naukowe
Tytuł:
Untranslated Region Sequences and the Efficacy of mRNA Vaccines against Tuberculosis.
Autorzy:
Reshetnikov V; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Terenin I; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Shepelkova G; Central Tuberculosis Research Institute, 107564 Moscow, Russia.
Yeremeev V; Central Tuberculosis Research Institute, 107564 Moscow, Russia.
Kolmykov S; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Nagornykh M; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kolosova E; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Sokolova T; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Zaborova O; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kukushkin I; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kazakova A; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kunyk D; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kirshina A; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Vasileva O; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Seregina K; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Pateev I; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kolpakov F; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Ivanov R; Translational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 10; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Tuberculosis*
Blood Group Antigens*
Mice ; Animals ; Humans ; Mice, Inbred C57BL ; mRNA Vaccines ; 5' Untranslated Regions/genetics ; 3' Untranslated Regions/genetics ; BNT162 Vaccine ; Pandemics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Screening of novel tumor-associated antigens for lung adenocarcinoma mRNA vaccine development based on pyroptosis phenotype genes.
Autorzy:
Zhou F; Department of Thoracic Surgery, Tianjin Chest Hospital of Tianjin University, 261 Taierzhuang South Road, Jinnan District, Tianjin, 300222, China.
Wang M; Department of Thoracic Surgery, Tianjin Chest Hospital of Tianjin University, 261 Taierzhuang South Road, Jinnan District, Tianjin, 300222, China.
Wang Z; Department of Thoracic Surgery, Tianjin Chest Hospital of Tianjin University, 261 Taierzhuang South Road, Jinnan District, Tianjin, 300222, China.
Li W; Department of Thoracic Surgery, Tianjin Chest Hospital of Tianjin University, 261 Taierzhuang South Road, Jinnan District, Tianjin, 300222, China.
Lu X; Department of Thoracic Surgery, Tianjin Chest Hospital of Tianjin University, 261 Taierzhuang South Road, Jinnan District, Tianjin, 300222, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Jan 02; Vol. 24 (1), pp. 28. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/genetics
Adenocarcinoma*/genetics
Lung Neoplasms*/genetics
Humans ; mRNA Vaccines ; NLR Family, Pyrin Domain-Containing 3 Protein ; Pyroptosis/genetics ; DNA Copy Number Variations ; Phenotype ; Antigens, Neoplasm/genetics ; Prognosis ; Tumor Microenvironment ; Neoplasm Proteins ; CARD Signaling Adaptor Proteins
Czasopismo naukowe
Tytuł:
Molecular Interaction of Nonsense-Mediated mRNA Decay with Viruses.
Autorzy:
Ahmed MR; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Du Z; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
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Źródło:
Viruses [Viruses] 2023 Mar 23; Vol. 15 (4). Date of Electronic Publication: 2023 Mar 23.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Nonsense Mediated mRNA Decay*
RNA Viruses*/genetics
Protein Biosynthesis ; Codon, Terminator ; Antiviral Agents
Czasopismo naukowe
Tytuł:
Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20 and Tma22 in nonsense-mediated decay.
Autorzy:
Pacheco M; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
D'Orazio KN; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Lessen LN; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Veltri AJ; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Neiman Z; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Loll-Krippleber R; Department of Biochemistry and Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada.
Brown GW; Department of Biochemistry and Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada.
Green R; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2024 Mar 06; Vol. 14 (3).
Typ publikacji:
Journal Article
MeSH Terms:
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
RNA Helicases*/metabolism
Animals ; Nonsense Mediated mRNA Decay ; Ribosomes/genetics ; Ribosomes/metabolism ; RNA, Messenger/genetics ; Mammals/genetics
Czasopismo naukowe
Tytuł:
Comparable safety and non-inferior immunogenicity of the SARS-CoV-2 mRNA vaccine candidate PTX-COVID19-B and BNT162b2 in a phase 2 randomized, observer-blinded study.
Autorzy:
Reiter L; Providence Therapeutics Holdings Inc., 120-8832 Blackfoot Trail SE, Calgary, AB, T2J 3J1, Canada.
Greffrath J; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Zidel B; Malton Medical Center, 6870 Goreway Dr., Mississauga, ON, L4V 1P1, Canada.
Ostrowski M; Department of Medicine, Immunology, University of Toronto, Medical Sciences Building, Rm 6271. 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.
Gommerman J; Department of Immunology, Temerty Faculty of Medicine, 1 King's College Circle, Rm. 7233, Toronto, ON, M5S 1A8, Canada.
Madhi SA; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Tran R; Providence Therapeutics Holdings Inc., 120-8832 Blackfoot Trail SE, Calgary, AB, T2J 3J1, Canada.
Martin-Orozco N; Providence Therapeutics Holdings Inc., 120-8832 Blackfoot Trail SE, Calgary, AB, T2J 3J1, Canada.
Panicker RKG; Providence Therapeutics Holdings Inc., 120-8832 Blackfoot Trail SE, Calgary, AB, T2J 3J1, Canada.
Cooper C; The Ottawa Hospital Viral Hepatitis Program, Division of Infectious Diseases, Department of Medicine, The Ottawa Hospital, University of Ottawa, 75 Laurier Ave. East, Ottawa, ON, K1N 6N5, Canada.
Pastrak A; Providence Therapeutics Holdings Inc., 120-8832 Blackfoot Trail SE, Calgary, AB, T2J 3J1, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5365. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
MeSH Terms:
COVID-19*/prevention & control
COVID-19 Vaccines*/adverse effects
Adult ; Humans ; Antibodies, Neutralizing ; BNT162 Vaccine ; CD59 Antigens ; mRNA Vaccines ; Pandemics ; SARS-CoV-2
Czasopismo naukowe
Tytuł:
Comparative efficacy and safety of COVID-19 vaccines in phase III trials: a network meta-analysis.
Autorzy:
Wu X; Medical School of Nanjing University, Nanjing, 210000, China.
Xu K; Medical School of Nanjing University, Nanjing, 210000, China.
Zhan P; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Liu H; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Zhang F; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Song Y; Medical School of Nanjing University, Nanjing, 210000, China. .; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China. .
Lv T; Medical School of Nanjing University, Nanjing, 210000, China. .; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Feb 21; Vol. 24 (1), pp. 234. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Meta-Analysis; Review; Journal Article
MeSH Terms:
COVID-19*/prevention & control
Vaccines*
Adult ; Humans ; Aged ; mRNA Vaccines ; Network Meta-Analysis ; BNT162 Vaccine ; SARS-CoV-2 ; COVID-19 Vaccines/adverse effects ; Clinical Trials, Phase III as Topic
Czasopismo naukowe
Tytuł:
Discovery of lung adenocarcinoma tumor antigens and ferroptosis subtypes for developing mRNA vaccines.
Autorzy:
Chen Y; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China.
Zhang C; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China.
Li Y; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China.
Tan X; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China.
Li W; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China.
Tan S; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China.
Liu G; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangxi Medical University, Daxue East Road No.166, Nanning, 530007, Guangxi, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 08; Vol. 14 (1), pp. 3219. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*/genetics
Adenocarcinoma of Lung*/genetics
Lung Neoplasms*/genetics
Humans ; Antigens, Neoplasm/genetics ; mRNA Vaccines ; RNA, Messenger/genetics ; Membrane Proteins/genetics ; RNA-Binding Proteins ; Nerve Tissue Proteins ; Connexins
Czasopismo naukowe
Tytuł:
The Anti-SARS-CoV-2 IgG1 and IgG3 Antibody Isotypes with Limited Neutralizing Capacity against Omicron Elicited in a Latin Population a Switch toward IgG4 after Multiple Doses with the mRNA Pfizer-BioNTech Vaccine.
Autorzy:
Espino AM; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Armina-Rodriguez A; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Alvarez L; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Ocasio-Malavé C; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Ramos-Nieves R; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Rodriguez Martinó EI; Gastroenterology Research Unit, School of Medicine, University of Puerto Rico, San Juan, PR 00925, USA.; Department of Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
López-Marte P; Gastroenterology Research Unit, School of Medicine, University of Puerto Rico, San Juan, PR 00925, USA.; Department of Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Torres EA; Gastroenterology Research Unit, School of Medicine, University of Puerto Rico, San Juan, PR 00925, USA.; Department of Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
Sariol CA; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.; Department of Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.; Unit of Comparative Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.
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Źródło:
Viruses [Viruses] 2024 Jan 26; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin G*
COVID-19*/prevention & control
Humans ; mRNA Vaccines ; SARS-CoV-2/genetics ; Vaccination ; RNA, Messenger/genetics ; Antibodies, Neutralizing ; Antibodies, Viral
Czasopismo naukowe
Tytuł:
Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis.
Autorzy:
Naveed M; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Punjab, Pakistan. .
Ali U; Department of Biotechnology, Quaid-I-Azam University Islamabad, Islamabad, 45320, Pakistan.
Aziz T; Laboratory of Animal Health, Food Hygiene and Quality, Department of Agriculture, University of Ioannina, 47132, Arta, Greece. .
Jabeen K; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Punjab, Pakistan.
Arif MH; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Punjab, Pakistan.
Alharbi M; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, 11451, Riyadh, Saudi Arabia.
Alasmari AF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, 11451, Riyadh, Saudi Arabia.
Albekairi TH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, 11451, Riyadh, Saudi Arabia.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 08; Vol. 14 (1), pp. 767. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Naegleria fowleri*/genetics
Central Nervous System Protozoal Infections*/prevention & control
Humans ; mRNA Vaccines ; Epitopes, T-Lymphocyte/genetics ; RNA, Messenger/genetics
Czasopismo naukowe

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