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Wyszukujesz frazę ""mRNA Cleavage and Polyadenylation Factors"" wg kryterium: Temat


Tytuł:
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Autorzy:
Ge Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Huang J; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Chen R; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Fu Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Ling T; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Ou X; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Rong X; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Cheng Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Lin Y; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Zhou F; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Lu C; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China.
Yuan S; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
Xu A; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Feb 28; Vol. 20 (2), pp. e1012061. Date of Electronic Publication: 2024 Feb 28 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
mRNA Cleavage and Polyadenylation Factors*/genetics
mRNA Cleavage and Polyadenylation Factors*/metabolism
Polyadenylation*
Virus Diseases*/genetics
Humans ; 3' Untranslated Regions/genetics ; Down-Regulation ; Immunity/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Mice ; Animals
Czasopismo naukowe
Tytuł:
A Combinatorial Code for CPEB-Mediated c-myc Repression.
Autorzy:
Ogami K; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.; Division of Molecular Oncology, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Ogawa K; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Sanpei S; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Ichikawa F; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Udagawa T; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Hoshino SI; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
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Źródło:
Cells [Cells] 2023 Oct 06; Vol. 12 (19). Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
mRNA Cleavage and Polyadenylation Factors*/metabolism
Oocytes*/metabolism
RNA/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Transcription Factors/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Calmodulin binds the N-terminus of the functional amyloid Orb2A inhibiting fibril formation.
Autorzy:
Soria MA; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Cervantes SA; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Siemer AB; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Jan 13; Vol. 17 (1), pp. e0259872. Date of Electronic Publication: 2022 Jan 13 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Amyloid/*metabolism
Calmodulin/*metabolism
Drosophila Proteins/*metabolism
Transcription Factors/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Amino Acid Sequence ; Animals ; Binding Sites ; Calmodulin/chemistry ; Drosophila/metabolism ; Drosophila Proteins/chemistry ; Drosophila Proteins/genetics ; Protein Binding ; Protein Domains ; Protein Isoforms/chemistry ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Transcription Factors/chemistry ; Transcription Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/chemistry ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection.
Autorzy:
Luchsinger C; Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1301 Morris Park - Price Center 501, Bronx, NY, 10461, USA.
Lee K; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, 21702, USA.
Mardones GA; Facultad de Medicina Y Ciencia, Universidad San Sebastian, Arturo Prat 154, Valdivia, Chile.
KewalRamani VN; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, 21702, USA.
Diaz-Griffero F; Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1301 Morris Park - Price Center 501, Bronx, NY, 10461, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 06; Vol. 13 (1), pp. 10974. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
HIV Infections*
HIV Seropositivity*/metabolism
HIV-1*/genetics
Humans ; Biomolecular Condensates ; Capsid/metabolism ; Capsid Proteins/metabolism ; Cell Nucleus/metabolism ; mRNA Cleavage and Polyadenylation Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/metabolism ; Virus Replication
Czasopismo naukowe
Tytuł:
3'UTR of mRNA Encoding CPEB Protein Orb2 Plays an Essential Role in Intracellular Transport in Neurons.
Autorzy:
Kozlov EN; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Deev RV; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Tokmatcheva EV; Institute of Physiology, Russian Academy of Sciences, 188680 St. Petersburg, Russia.
Tvorogova A; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Kachaev ZM; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Gilmutdinov RA; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Zhukova M; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Savvateeva-Popova EV; Institute of Physiology, Russian Academy of Sciences, 188680 St. Petersburg, Russia.
Schedl P; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.; Department of Molecular Biology, Princeton University, Princeton, NJ 08544-1014, USA.
Shidlovskii YV; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.; Department of Biology and General Genetics, Sechenov First Moscow State Medical University (Sechenov University), 119992 Moscow, Russia.
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Źródło:
Cells [Cells] 2023 Jun 25; Vol. 12 (13). Date of Electronic Publication: 2023 Jun 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carrier Proteins*/metabolism
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Animals ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; 3' Untranslated Regions/genetics ; mRNA Cleavage and Polyadenylation Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/metabolism ; Polyadenylation/genetics ; Drosophila/genetics ; Drosophila/metabolism ; Neurons/metabolism
Czasopismo naukowe
Tytuł:
Alternative polyadenylation factor CPSF6 regulates temperature compensation of the mammalian circadian clock.
Autorzy:
Schmal C; Institute for Theoretical Biology, Humboldt-Universität zu Berlin and Charité-Universitätsmedizin Berlin, Berlin, Germany.
Maier B; Laboratory of Chronobiology, Institute for Medical immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Ashwal-Fluss R; Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
Bartok O; Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
Finger AM; Laboratory of Chronobiology, Institute for Medical immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Bange T; Institute of Medical Psychology, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.
Koutsouli S; Institute of Medical Psychology, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.
Robles MS; Institute of Medical Psychology, Faculty of Medicine, Ludwig-Maximilians-Universität München, München, Germany.
Kadener S; Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.; Department of Biology, Brandeis University, Waltham, Massachusetts, United States of America.
Herzel H; Institute for Theoretical Biology, Humboldt-Universität zu Berlin and Charité-Universitätsmedizin Berlin, Berlin, Germany.
Kramer A; Laboratory of Chronobiology, Institute for Medical immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
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Źródło:
PLoS biology [PLoS Biol] 2023 Jun 28; Vol. 21 (6), pp. e3002164. Date of Electronic Publication: 2023 Jun 28 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Circadian Clocks*/genetics
Animals ; Humans ; Circadian Rhythm/genetics ; Mammals ; mRNA Cleavage and Polyadenylation Factors/genetics ; Phosphorylation ; Temperature
Czasopismo naukowe
Tytuł:
An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing.
Autorzy:
Shimada Y; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Carl SH; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
Skribbe M; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Flury V; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Kuzdere T; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Kempf G; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Bühler M; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.; University of Basel, Basel, Switzerland.
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Źródło:
PLoS genetics [PLoS Genet] 2021 Jun 22; Vol. 17 (6), pp. e1009645. Date of Electronic Publication: 2021 Jun 22 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Fungal*
Gene Silencing*
RNA, Messenger/*genetics
RNA, Small Interfering/*genetics
Schizosaccharomyces/*genetics
mRNA Cleavage and Polyadenylation Factors/*genetics
Alleles ; Amino Acid Substitution ; Centromere/chemistry ; Centromere/metabolism ; Chromatin Assembly and Disassembly ; Gene Expression Profiling ; Heterochromatin/chemistry ; Heterochromatin/metabolism ; Kinetics ; Models, Genetic ; Molecular Sequence Annotation ; Mutation ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Schizosaccharomyces/metabolism ; mRNA Cleavage and Polyadenylation Factors/metabolism
Czasopismo naukowe
Tytuł:
Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22.
Autorzy:
Benjamin B; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, New York, United States of America.
Sanchez AM; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, New York, United States of America.
Garg A; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.
Schwer B; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.
Shuman S; Molecular Biology Program, Sloan-Kettering Institute, New York, New York, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2021 Mar 12; Vol. 17 (3), pp. e1009452. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Protein Interaction Domains and Motifs*
Acid Anhydride Hydrolases/*metabolism
Protein Phosphatase 1/*metabolism
Schizosaccharomyces/*physiology
mRNA Cleavage and Polyadenylation Factors/*metabolism
Alleles ; Amino Acid Sequence ; Computational Biology/methods ; Gene Expression Profiling ; Gene Expression Regulation, Fungal ; Models, Biological ; Mutation ; Phenotype ; Phosphorylation ; Transcription, Genetic ; Transcriptome ; mRNA Cleavage and Polyadenylation Factors/chemistry
Czasopismo naukowe
Tytuł:
CPSF6 links alternative polyadenylation to metabolism adaption in hepatocellular carcinoma progression.
Autorzy:
Tan S; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhang M; Department of Integrated Traditional Chinese and Western Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, China.
Shi X; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ding K; Department of Pathology, School of Basic Medicine, Anhui Medical University, Hefei, 230032, Anhui, China.
Zhao Q; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Guo Q; Department of Pathology, School of Basic Medicine, Anhui Medical University, Hefei, 230032, Anhui, China.
Wang H; Department of Pathology, School of Basic Medicine, Anhui Medical University, Hefei, 230032, Anhui, China.
Wu Z; Department of Pathology, School of Basic Medicine, Anhui Medical University, Hefei, 230032, Anhui, China.
Kang Y; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhu T; Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China. .
Sun J; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China. .
Zhao X; Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, 200240, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2021 Mar 01; Vol. 40 (1), pp. 85. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*metabolism
Liver Neoplasms/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Disease Progression ; Hep G2 Cells ; Heterografts ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Male ; Mice ; Mice, Nude ; NAD(P)H Dehydrogenase (Quinone)/genetics ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; Polyadenylation ; Survival Analysis ; Up-Regulation ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
miR-129-3p alleviates chondrocyte apoptosis in knee joint fracture-induced osteoarthritis through CPEB1.
Autorzy:
Chen R; Department of Orthopedics, Guangzhou Red Cross Hospital Affiliated to Jinan University, No. 396, Mid Tongfu Road, Haizhu District, Guangzhou, 510000, Guangdong, People's Republic of China.
Ye B; Department of Orthopedics, Guangzhou Red Cross Hospital Affiliated to Jinan University, No. 396, Mid Tongfu Road, Haizhu District, Guangzhou, 510000, Guangdong, People's Republic of China.
Xie H; Department of Orthopedics, Huizhou Central People's Hospital, Huizhou, 516000, Guangdong, People's Republic of China.
Huang Y; Department of Orthopedics, Huizhou Central People's Hospital, Huizhou, 516000, Guangdong, People's Republic of China.
Wu Z; Department of Orthopedics, Huizhou Central People's Hospital, Huizhou, 516000, Guangdong, People's Republic of China.
Wu H; Department of Orthopedics, Huizhou Central People's Hospital, Huizhou, 516000, Guangdong, People's Republic of China.
Wang X; Department of Orthopedics, Huizhou Central People's Hospital, Huizhou, 516000, Guangdong, People's Republic of China.
Miao H; Department of Orthopedics, Guangzhou Red Cross Hospital Affiliated to Jinan University, No. 396, Mid Tongfu Road, Haizhu District, Guangzhou, 510000, Guangdong, People's Republic of China. .
Liang W; Department of Orthopedics, Guangzhou Red Cross Hospital Affiliated to Jinan University, No. 396, Mid Tongfu Road, Haizhu District, Guangzhou, 510000, Guangdong, People's Republic of China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2020 Nov 23; Vol. 15 (1), pp. 552. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
Chondrocytes/*metabolism
Chondrocytes/*pathology
Knee Injuries/*complications
MicroRNAs/*genetics
MicroRNAs/*metabolism
Osteoarthritis, Knee/*etiology
Osteoarthritis, Knee/*genetics
Transcription Factors/*genetics
Transcription Factors/*metabolism
mRNA Cleavage and Polyadenylation Factors/*genetics
mRNA Cleavage and Polyadenylation Factors/*metabolism
Animals ; Arthroplasty, Replacement, Knee ; Cartilage, Articular/cytology ; Cell Survival/genetics ; Cells, Cultured ; Collagen Type II/metabolism ; Female ; Gene Expression ; Gene Expression Regulation, Developmental ; Knee Injuries/surgery ; Knee Joint/surgery ; Male ; MicroRNAs/physiology ; Osteoarthritis, Knee/pathology ; Rats, Wistar ; Transcription Factors/physiology ; mRNA Cleavage and Polyadenylation Factors/physiology
Czasopismo naukowe
Tytuł:
Detection of FIP1L1-PDGFRA fusion gene-positive cells in the skin lesion of a patient with hypereosinophilic syndrome.
Autorzy:
Kitayama S; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Makino T; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Yoto A; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Mori S; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Furukawa F; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Torai R; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Mizawa M; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Shimizu T; Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
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Źródło:
Clinical and experimental dermatology [Clin Exp Dermatol] 2023 Mar 22; Vol. 48 (4), pp. 364-367.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Hypereosinophilic Syndrome*/diagnosis
Hypereosinophilic Syndrome*/genetics
Hypereosinophilic Syndrome*/pathology
Male ; Humans ; Aged ; In Situ Hybridization, Fluorescence ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Receptor, Platelet-Derived Growth Factor alpha/metabolism ; Imatinib Mesylate/therapeutic use ; Eosinophils/pathology ; Oncogene Proteins, Fusion/genetics ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
Implications of the Orb2 Amyloid Structure in Huntington's Disease.
Autorzy:
Hervás R; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.
Murzin AG; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Si K; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 21; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyloid/*metabolism
Drosophila Proteins/*metabolism
Huntington Disease/*metabolism
Transcription Factors/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Amyloid/genetics ; Animals ; Drosophila Proteins/genetics ; Drosophila melanogaster ; Humans ; Huntington Disease/genetics ; Transcription Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
Increased RNA production in Saccharomyces cerevisiae by simultaneously overexpressing FHL1, IFH1, and SSF2 and deleting HRP1.
Autorzy:
Guo X; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China. .; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China. .; Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, Tianjin, 300457, China. .; Department of Fermentation Engineering, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China. .
Zhao B; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China.
Zhou X; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China.
Ni X; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China.
Lu D; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China.
Chen T; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.
Chen Y; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China.; Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, Tianjin, 300457, China.
Xiao D; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Industrial Microbiology Key Lab, College of Biotechnology of Tianjin University of Science and Technology, Tianjin, 300547, China.; Tianjin Food Safety & Low Carbon Manufacturing Collaborative Innovation Center, Tianjin, 300457, China.; Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, Tianjin, 300457, China.
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Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2020 Sep; Vol. 104 (18), pp. 7901-7913. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji:
Journal Article
MeSH Terms:
Nuclear Proteins*
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Trans-Activators*/genetics
mRNA Cleavage and Polyadenylation Factors*
Forkhead Transcription Factors/metabolism ; Gene Expression Regulation, Fungal ; RNA ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6.
Autorzy:
Xie L; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Chen L; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Zhong C; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Yu T; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Ju Z; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Wang M; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Xiong H; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Zeng Y; Department of Zoology, College of Life Sciences, Nanjing Agriculture University, Nanjing, Jiangsu, People's Republic of China.
Wang J; Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, People's Republic of China.
Hu H; Department of Microbiology and Immunology, Sealy Center for Vaccine Development and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
Hou W; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China. .
Feng Y; State Key Laboratory of Virology/Institute of Medical Virology/Hubei Province Key Laboratory of Allergy & Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China. .
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Źródło:
Retrovirology [Retrovirology] 2020 Jun 29; Vol. 17 (1), pp. 16. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Nucleus/*metabolism
HIV-1/*physiology
Molecular Chaperones/*metabolism
Myxovirus Resistance Proteins/*metabolism
Nuclear Pore Complex Proteins/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Active Transport, Cell Nucleus ; Capsid/metabolism ; Capsid Proteins/genetics ; Capsid Proteins/metabolism ; Humans ; Indoles/pharmacology ; Molecular Chaperones/genetics ; Myxovirus Resistance Proteins/genetics ; Nuclear Pore Complex Proteins/genetics ; Phenylalanine/analogs & derivatives ; Phenylalanine/pharmacology ; Protein Binding ; Virus Replication ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
Long-Term Memory Formation in Drosophila Depends on the 3'UTR of CPEB Gene orb2 .
Autorzy:
Kozlov EN; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Tokmatcheva EV; Institute of Physiology, Russian Academy of Sciences, 188680 St. Petersburg, Russia.
Khrustaleva AM; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Grebenshchikov ES; Department of Biology and General Genetics, Sechenov First Moscow State Medical University (Sechenov University), 119992 Moscow, Russia.
Deev RV; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Gilmutdinov RA; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Lebedeva LA; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Zhukova M; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Savvateeva-Popova EV; Institute of Physiology, Russian Academy of Sciences, 188680 St. Petersburg, Russia.
Schedl P; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.; Department of Molecular Biology, Princeton University, Princeton University, Princeton, NJ 08544-1014, USA.
Shidlovskii YV; Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.; Department of Biology and General Genetics, Sechenov First Moscow State Medical University (Sechenov University), 119992 Moscow, Russia.
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Źródło:
Cells [Cells] 2023 Jan 14; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drosophila*/metabolism
Drosophila Proteins*/genetics
Drosophila Proteins*/metabolism
Animals ; 3' Untranslated Regions/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism ; mRNA Cleavage and Polyadenylation Factors/genetics ; Memory, Long-Term/physiology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł:
RNA polymerase II transcription attenuation at the yeast DNA repair gene DEF1 is biologically significant and dependent on the Hrp1 RNA-recognition motif.
Autorzy:
Amodeo ME; Department of Cancer Immunology & Virology, Dana Farber Cancer Institute, Boston, MA 02215, USA.
Mitchell SPC; Alzheimer Research Unit, MassGeneral Institute for Neurodegenerative Disease, Charlestown, MA 02129, USA.
Pavan V; Department of Biology, Emmanuel College, Boston, MA 02115, USA.
Kuehner JN; Department of Biology, Emmanuel College, Boston, MA 02115, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2023 Jan 12; Vol. 13 (1).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; RNA Recognition Motif ; RNA, Messenger/genetics ; DNA Repair ; mRNA Cleavage and Polyadenylation Factors/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; DNA Helicases/metabolism ; RNA Helicases/metabolism
Czasopismo naukowe
Tytuł:
MicroRNA-320a inhibits invasion and metastasis in osteosarcoma by targeting cytoplasmic polyadenylation element-binding protein 1.
Autorzy:
Wang Y; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
Yang J; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
Chen P; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
Song Y; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
An W; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
Zhang H; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
Butegeleqi B; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
Yan J; Departments of Orthopedic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, P.R. China.
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Źródło:
Cancer medicine [Cancer Med] 2020 Apr; Vol. 9 (8), pp. 2833-2845. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Bone Neoplasms/*prevention & control
MicroRNAs/*genetics
Osteosarcoma/*prevention & control
Transcription Factors/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Bone Neoplasms/secondary ; Cell Movement ; Cell Proliferation ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Osteosarcoma/pathology ; Transcription Factors/genetics ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
Meiotic gene silencing complex MTREC/NURS recruits the nuclear exosome to YTH-RNA-binding protein Mmi1.
Autorzy:
Shichino Y; Laboratory of Cell Responses, National Institute for Basic Biology, Myodaiji, Okazaki, Aichi, Japan.
Otsubo Y; Laboratory of Cell Responses, National Institute for Basic Biology, Myodaiji, Okazaki, Aichi, Japan.; National Institute for Fusion Science, Toki, Gifu, Japan.; Center for Novel Science Initiatives, National Institutes of Natural Sciences, Myodaiji, Okazaki, Aichi, Japan.
Yamamoto M; Laboratory of Cell Responses, National Institute for Basic Biology, Myodaiji, Okazaki, Aichi, Japan.; Department of Basic Biology, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), Myodaiji, Okazaki, Aichi, Japan.
Yamashita A; Laboratory of Cell Responses, National Institute for Basic Biology, Myodaiji, Okazaki, Aichi, Japan.; Center for Novel Science Initiatives, National Institutes of Natural Sciences, Myodaiji, Okazaki, Aichi, Japan.; Department of Basic Biology, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), Myodaiji, Okazaki, Aichi, Japan.
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Źródło:
PLoS genetics [PLoS Genet] 2020 Feb 03; Vol. 16 (2), pp. e1008598. Date of Electronic Publication: 2020 Feb 03 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Fungal*
RNA Interference*
Carrier Proteins/*metabolism
Exosomes/*metabolism
Meiosis/*genetics
Schizosaccharomyces pombe Proteins/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
DEAD-box RNA Helicases/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Ribonucleases/genetics ; Ribonucleases/metabolism ; Schizosaccharomyces pombe Proteins/genetics ; mRNA Cleavage and Polyadenylation Factors/genetics
Czasopismo naukowe
Tytuł:
Molecular Insights into mRNA Polyadenylation and Deadenylation.
Autorzy:
Liu J; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Lu X; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhang S; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Yuan L; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Sun Y; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 20; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polyadenylation*
Saccharomyces cerevisiae Proteins*/metabolism
DNA-Binding Proteins/metabolism ; Exoribonucleases/genetics ; Humans ; Multiprotein Complexes/metabolism ; Poly(A)-Binding Proteins/metabolism ; RNA Precursors/metabolism ; RNA Stability ; RNA, Messenger/metabolism ; Saccharomyces cerevisiae/metabolism ; Ubiquitin-Protein Ligases/metabolism ; mRNA Cleavage and Polyadenylation Factors/metabolism
Czasopismo naukowe
Tytuł:
TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.
Autorzy:
Selyutina A; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Simons LM; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Kirby KA; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.; Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
Bulnes-Ramos A; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Hu P; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Sarafianos SG; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.; Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
Hultquist JF; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Diaz-Griffero F; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
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Źródło:
Viruses [Viruses] 2022 Feb 10; Vol. 14 (2). Date of Electronic Publication: 2022 Feb 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antiviral Restriction Factors/*metabolism
CD4-Positive T-Lymphocytes/*virology
Cyclophilin A/*metabolism
HIV-1/*physiology
Tripartite Motif Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Antiviral Restriction Factors/genetics ; CD4-Positive T-Lymphocytes/metabolism ; Capsid/chemistry ; Capsid/metabolism ; Capsid Proteins/chemistry ; Capsid Proteins/genetics ; Capsid Proteins/metabolism ; HIV-1/genetics ; Humans ; Mutation ; Protein Binding ; Protein Conformation ; Protein Stability ; Tripartite Motif Proteins/genetics ; Ubiquitin-Protein Ligases/genetics ; mRNA Cleavage and Polyadenylation Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/metabolism
Czasopismo naukowe

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