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Wyszukujesz frazę ""macromolecular substances"" wg kryterium: Temat


Tytuł:
Editorial overview: Modern and future methods for studying macromolecular assemblies in action.
Autorzy:
Brown A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA. Electronic address: alan_.
Fraternali F; Randall Centre for Cell and Molecular Biophysics, Faculty of Life Science and Medicine, King's College London, London, UK. Electronic address: .
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Źródło:
Current opinion in structural biology [Curr Opin Struct Biol] 2022 Aug; Vol. 75, pp. 102438. Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:
Editorial
MeSH Terms:
Macromolecular Substances*
Opinia redakcyjna
Tytuł:
Supramolecular Self-Assembly in Living Cells.
Autorzy:
Dergham M; Centre for Polymers in Medicine, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Nanshan, 518055, China.; University of Chinese Academy of Science, Beijing, 100049, China.
Lin S; Centre for Polymers in Medicine, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Nanshan, 518055, China.
Geng J; Centre for Polymers in Medicine, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Nanshan, 518055, China.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Apr 25; Vol. 61 (18), pp. e202114267. Date of Electronic Publication: 2022 Mar 23.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Macromolecular Substances*/chemistry
Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Polymerization ; Static Electricity
Czasopismo naukowe
Tytuł:
ProNAB: database for binding affinities of protein-nucleic acid complexes and their mutants.
Autorzy:
Harini K; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
Srivastava A; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
Kulandaisamy A; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
Gromiha MM; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Jan 07; Vol. 50 (D1), pp. D1528-D1534.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Databases, Protein*
Macromolecular Substances/*classification
Nucleic Acids/*genetics
Proteins/*genetics
DNA-Binding Proteins/genetics ; DNA-Binding Proteins/ultrastructure ; Macromolecular Substances/chemistry ; Macromolecular Substances/ultrastructure ; Mutation/genetics ; Nucleic Acids/ultrastructure ; Protein Binding/genetics ; Proteins/classification
Czasopismo naukowe
Tytuł:
Backbone thioamide directed macrocyclisation: lactam stapling of peptides.
Autorzy:
Taresh AB; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia. .
Hutton CA; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia. .
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2022 Feb 16; Vol. 20 (7), pp. 1488-1492. Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lactams/*chemistry
Macromolecular Substances/*chemical synthesis
Peptides, Cyclic/*chemical synthesis
Thioamides/*chemistry
Macromolecular Substances/chemistry ; Molecular Structure ; Peptides, Cyclic/chemistry
Czasopismo naukowe
Tytuł:
Preferential Interactions of a Crowder Protein with the Specific Binding Site of a Native Protein Complex.
Autorzy:
Dong X; CAS Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic Molecular Physics, National Center for Magnetic Resonance at Wuhan, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, Hubei430071, China.
Qin LY; CAS Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic Molecular Physics, National Center for Magnetic Resonance at Wuhan, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, Hubei430071, China.; University of Chinese Academy of Sciences, Beijing100049, China.
Gong Z; CAS Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic Molecular Physics, National Center for Magnetic Resonance at Wuhan, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, Hubei430071, China.
Qin S; Department of Chemistry and Department of Physics, University of Illinois at Chicago, Chicago, Illinois60607, United States.; Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida32306, United States.
Zhou HX; Department of Chemistry and Department of Physics, University of Illinois at Chicago, Chicago, Illinois60607, United States.
Tang C; Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, and Peking-Tsinghua Center for Life Sciences, Center for Computational Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing100871, China.
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Źródło:
The journal of physical chemistry letters [J Phys Chem Lett] 2022 Jan 27; Vol. 13 (3), pp. 792-800. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Macromolecular Substances*
Czasopismo naukowe
Tytuł:
Functional Macromolecular Adhesives for Bone Fracture Healing.
Autorzy:
Zhang M; Department of Orthopedics, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130033, People's Republic of China.; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.
Liu J; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.; Jilin Collaborative Innovation Center for Antibody Engineering, Jilin Medical University, 5 Jilin Street, Jilin 132000, People's Republic of China.
Zhu T; Department of Orthopedics, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130033, People's Republic of China.; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.
Le H; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.; Orthopaedic Medical Center, The Second Hospital of Jilin University, 218 Ziqiang Street, Changchun 130041, People's Republic of China.
Wang X; Department of Orthopedics, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130033, People's Republic of China.; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.
Guo J; Department of Histology and Embryology, School of Basic Medical Sciences; Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Southern Medical University, 1023 Southern Shatai Road, Guangzhou 510515, People's Republic of China.
Liu G; Department of Orthopedics, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130033, People's Republic of China.
Ding J; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.
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Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2022 Jan 12; Vol. 14 (1), pp. 1-19. Date of Electronic Publication: 2021 Dec 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Fracture Healing/*drug effects
Fractures, Bone/*drug therapy
Macromolecular Substances/*pharmacology
Tissue Adhesives/*pharmacology
Animals ; Bone Regeneration/drug effects ; Bone and Bones/drug effects ; Cell Line, Tumor ; Humans ; Macromolecular Substances/chemistry ; Osseointegration/drug effects ; Tissue Adhesives/chemistry ; Tissue Engineering ; Tissue Scaffolds/chemistry
Czasopismo naukowe
Tytuł:
Optimization of intracellular macromolecule delivery by nanoparticle-mediated photoporation.
Autorzy:
Kumar S; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Li A; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Thadhani NN; School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Prausnitz MR; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA. Electronic address: .
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Źródło:
Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2021 Oct; Vol. 37, pp. 102431. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Drug Delivery Systems*
Macromolecular Substances/*pharmacology
Nanoparticles/*chemistry
Prostatic Neoplasms/*drug therapy
Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Humans ; Lasers ; Light ; Macromolecular Substances/chemistry ; Macromolecular Substances/radiation effects ; Male ; Nanoparticles/radiation effects ; Prostatic Neoplasms/pathology ; Soot/chemistry ; Soot/pharmacology
Czasopismo naukowe
Tytuł:
The role of natural biological macromolecules: Deoxyribonucleic and ribonucleic acids in the formulation of new stable charge transfer complexes of thiophene Schiff bases for various life applications.
Autorzy:
El-Mossalamy EH; Chemistry Department, Faculty of Science, Benha University, Benha 13518, Egypt.
Batouti MEL; Chemistry Department, Faculty of Science, Alexandria University, Egypt. Electronic address: .
Fetouh HA; Chemistry Department, Faculty of Science, Alexandria University, Egypt. Electronic address: howida_.
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2021 Dec 15; Vol. 193 (Pt B), pp. 1572-1586. Date of Electronic Publication: 2021 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Products/*chemistry
Coordination Complexes/*chemistry
DNA/*chemistry
Macromolecular Substances/*chemistry
Schiff Bases/*chemistry
Thiophenes/*chemistry
Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Biological Products/pharmacology ; Fungi/drug effects ; Furans/chemistry ; Furans/pharmacology ; Macromolecular Substances/pharmacology ; Magnetic Resonance Spectroscopy/methods ; Microbial Sensitivity Tests/methods ; Molecular Structure ; RNA/chemistry ; Spectroscopy, Fourier Transform Infrared/methods ; Sugars/chemistry
Czasopismo naukowe
Tytuł:
Cryo-EM density maps adjustment for subtraction, consensus and sharpening.
Autorzy:
Fernández-Giménez E; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain; Univ. Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain.
Martínez M; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain.
Sánchez-García R; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain.
Marabini R; Univ. Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain.
Ramírez-Aportela E; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain.
Conesa P; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain.
Carazo JM; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain.
Sorzano COS; Centro Nac. Biotecnología (CSIC), c/Darwin, 3, 28049 Cantoblanco, Madrid, Spain; Univ. San Pablo - CEU, Campus Urb. Montepríncipe, 28668 Boadilla del Monte, Madrid, Spain. Electronic address: .
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Źródło:
Journal of structural biology [J Struct Biol] 2021 Dec; Vol. 213 (4), pp. 107780. Date of Electronic Publication: 2021 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Algorithms*
Cryoelectron Microscopy/*methods
Image Processing, Computer-Assisted/*methods
Imaging, Three-Dimensional/*methods
Macromolecular Substances/*ultrastructure
Capsid/chemistry ; Capsid/ultrastructure ; Hepatitis B virus/ultrastructure ; Macromolecular Substances/chemistry ; Models, Molecular ; Molecular Conformation ; Protein Conformation ; Reproducibility of Results ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/ultrastructure
Czasopismo naukowe
Tytuł:
Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks.
Autorzy:
Koehler Leman J; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, 10010, USA. .; Department of Biology, New York University, New York, NY, 10003, USA. .
Lyskov S; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Lewis SM; Cyrus Biotechnology, 1201 Second Ave, Suite 900, Seattle, WA, 98101, USA.
Adolf-Bryfogle J; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research, La Jolla, CA, 92037, USA.
Alford RF; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Barlow K; Graduate Program in Bioinformatics, University of California San Francisco, San Francisco, CA, 94158, USA.
Ben-Aharon Z; Department of Microbiology and Molecular Genetics, Hebrew University, Hadassah Medical School, POB 12272, Jerusalem, 91120, Israel.
Farrell D; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
Fell J; Genome Center, University of California, Davis, CA, 95616, USA.; Department of Biochemistry & Molecular Medicine, University of California, Davis, CA, 95616, USA.; Department of Chemistry, University of California, Davis, CA, 95616, USA.
Hansen WA; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08904, USA.; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ, 08904, USA.
Harmalkar A; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Jeliazkov J; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
Kuenze G; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA.; Institute for Drug Discovery, Medical School, Leipzig University, 04103, Leipzig, Germany.
Krys JD; Faculty of Chemistry, Biological and Chemical Research Center, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland.
Ljubetič A; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
Loshbaugh AL; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.; Biophysics Graduate Program, University of California San Francisco, San Francisco, CA, 94158, USA.
Maguire J; Program in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Moretti R; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA.
Mulligan VK; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, 10010, USA.
Nance ML; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
Nguyen PT; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, 95616, USA.
Ó Conchúir S; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.
Roy Burman SS; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Samanta R; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Smith ST; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA.; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN, 37235, USA.
Teets F; Department of Bioochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27516, USA.
Tiemann JKS; Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, DK-2200, Copenhagen N., Denmark.
Watkins A; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Woods H; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA.; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN, 37235, USA.
Yachnin BJ; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08904, USA.; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ, 08904, USA.
Bahl CD; Institute for Protein Innovation, Boston, MA, 02115, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
Bailey-Kellogg C; Department of Computer Science, Dartmouth, Hanover, NH, 03755, USA.
Baker D; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
Das R; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, 94305, USA.
DiMaio F; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
Khare SD; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08904, USA.; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ, 08904, USA.
Kortemme T; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.; Biophysics Graduate Program, University of California San Francisco, San Francisco, CA, 94158, USA.
Labonte JW; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Lindorff-Larsen K; Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, DK-2200, Copenhagen N., Denmark.
Meiler J; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA.; Institute for Drug Discovery, Medical School, Leipzig University, 04103, Leipzig, Germany.
Schief W; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research, La Jolla, CA, 92037, USA.
Schueler-Furman O; Department of Microbiology and Molecular Genetics, Hebrew University, Hadassah Medical School, POB 12272, Jerusalem, 91120, Israel.
Siegel JB; Genome Center, University of California, Davis, CA, 95616, USA.; Department of Biochemistry & Molecular Medicine, University of California, Davis, CA, 95616, USA.; Department of Chemistry, University of California, Davis, CA, 95616, USA.
Stein A; Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, DK-2200, Copenhagen N., Denmark.
Yarov-Yarovoy V; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA, 95616, USA.
Kuhlman B; Department of Bioochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27516, USA.
Leaver-Fay A; Department of Bioochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27516, USA.
Gront D; Faculty of Chemistry, Biological and Chemical Research Center, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland.
Gray JJ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA. .
Bonneau R; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, 10010, USA. .; Department of Biology, New York University, New York, NY, 10003, USA. .; Department of Computer Science, New York University, New York, NY, 10003, USA. .
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Źródło:
Nature communications [Nat Commun] 2021 Nov 29; Vol. 12 (1), pp. 6947. Date of Electronic Publication: 2021 Nov 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Molecular Docking Simulation*
Macromolecular Substances/*chemistry
Proteins/*chemistry
Software/*standards
Benchmarking ; Binding Sites ; Humans ; Ligands ; Macromolecular Substances/metabolism ; Protein Binding ; Proteins/metabolism ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Tunable, biodegradable grafting-from glycopolypeptide bottlebrush polymers.
Autorzy:
Clauss ZS; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, 84102, USA.
Wardzala CL; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, 84102, USA.
Schlirf AE; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, 84102, USA.
Wright NS; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, 84102, USA.
Saini SS; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, 84102, USA.
Onoa B; Howard Hughes Medical Institute University of California Berkeley, Berkeley, CA, 94720, USA.
Bustamante C; Howard Hughes Medical Institute University of California Berkeley, Berkeley, CA, 94720, USA.; Department of Chemistry, University of California Berkeley, Berkeley, CA, 94720, USA.; Institute for Quantitative Biosciences, University of California, Berkeley, CA, 94720, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.; Department of Physics, University of California Berkeley, Berkeley, CA, 94720, USA.; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, 94720, USA.
Kramer JR; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, 84102, USA. .; Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah, 84102, USA. .
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Źródło:
Nature communications [Nat Commun] 2021 Nov 09; Vol. 12 (1), pp. 6472. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Macromolecular Substances/*metabolism
Polymers/*metabolism
Extracellular Matrix/metabolism ; Glycosylation ; Humans ; Macromolecular Substances/chemistry ; Polymerization ; Polymers/chemistry ; Proteoglycans/metabolism
Czasopismo naukowe
Tytuł:
Artificial Metal-Peptide Assemblies: Bioinspired Assembly of Peptides and Metals through Space and across Length Scales.
Autorzy:
Dong J; School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China.
Liu Y; School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China.
Cui Y; School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China.
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Źródło:
Journal of the American Chemical Society [J Am Chem Soc] 2021 Oct 27; Vol. 143 (42), pp. 17316-17336. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coordination Complexes/*chemistry
Macromolecular Substances/*chemistry
Metals/*chemistry
Peptides/*chemistry
Catenanes/chemistry ; Coordination Complexes/chemical synthesis ; Hydrophobic and Hydrophilic Interactions ; Macromolecular Substances/chemical synthesis ; Porosity ; Protein Conformation ; Stereoisomerism
Czasopismo naukowe
Tytuł:
Computational Evaluation of Abrogation of HBx-Bcl-xL Complex with High-Affinity Carbon Nanotubes (Fullerene) to Halt the Hepatitis B Virus Replication.
Autorzy:
Khan A; Foundation University Medical College, Foundation University Islamabad, DHA-I, Islamabad 44000, Pakistan.
Ahsan O; Foundation University Medical College, Foundation University Islamabad, DHA-I, Islamabad 44000, Pakistan.
Wei DQ; Department of Bioinformatics and Biological Statistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Centre on Antibacterial Resistances, Joint Laboratory of International Laboratory of Metabolic and Developmental Sciences, Ministry of Education and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.; Peng Cheng Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nashan District, Shenzhen 518055, China.
Ansari JK; Foundation University Medical College, Foundation University Islamabad, DHA-I, Islamabad 44000, Pakistan.
Najmi MH; Foundation University Medical College, Foundation University Islamabad, DHA-I, Islamabad 44000, Pakistan.
Muhammad K; Department of Biology, College of Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates.
Waheed Y; Foundation University Medical College, Foundation University Islamabad, DHA-I, Islamabad 44000, Pakistan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Oct 25; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
Nanotubes, Carbon*/chemistry
Virus Replication*
Macromolecular Substances/*chemistry
Trans-Activators/*chemistry
Trans-Activators/*metabolism
Viral Regulatory and Accessory Proteins/*chemistry
Viral Regulatory and Accessory Proteins/*metabolism
bcl-X Protein/*chemistry
bcl-X Protein/*metabolism
Binding Sites ; Hepatitis B virus/physiology ; Humans ; Macromolecular Substances/metabolism ; Models, Molecular ; Molecular Conformation ; Protein Binding ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Controlling the semi-permeability of protein nanocapsules influences the cellular response to macromolecular payloads.
Autorzy:
Machtakova M; Max Planck Institute for Polymer Research, Mainz, Germany. .
Wirsching S; Children's Hospital, University Medical Center, Johannes Gutenberg University, Mainz, Germany.
Gehring S; Children's Hospital, University Medical Center, Johannes Gutenberg University, Mainz, Germany.
Landfester K; Max Planck Institute for Polymer Research, Mainz, Germany. .
Thérien-Aubin H; Max Planck Institute for Polymer Research, Mainz, Germany. .; Department of Chemistry, Memorial University of Newfoundland, St. John's, NL, Canada. .
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Źródło:
Journal of materials chemistry. B [J Mater Chem B] 2021 Oct 20; Vol. 9 (40), pp. 8389-8398. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Macromolecular Substances/*administration & dosage
Nanocapsules/*chemistry
Proteins/*chemistry
Drug Delivery Systems ; Drug Liberation ; Endopeptidase K/metabolism ; Fluorescamine ; Macromolecular Substances/chemistry ; Permeability ; Vaccines/administration & dosage
Czasopismo naukowe
Tytuł:
A mixing microfluidic chip for real-time NMR monitoring of macromolecular reactions.
Autorzy:
Yamasaki K; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 3058566, Japan.
Yamasaki T; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 3058566, Japan.
Takahashi M; Planning Headquarters, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki 3058560, Japan.
Suematsu H; JEOL RESONANCE Inc., 3-1-2 Musashino, Akishima, Tokyo 1968558, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2021 Oct 12; Vol. 170 (3), pp. 363-368.
Typ publikacji:
Journal Article
MeSH Terms:
Macromolecular Substances/*metabolism
Magnetic Resonance Spectroscopy/*methods
Microfluidics/*methods
Kinetics ; Macromolecular Substances/chemistry ; Protein Folding ; Proteins/metabolism
Czasopismo naukowe
Tytuł:
Biotinylated chitosan macromolecule based nanosystems: A review from chemical design to biological targets.
Autorzy:
Balan V; Faculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700115, Romania. Electronic address: .
Dodi G; Advanced Centre for Research-Development in Experimental Medicine, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700115, Romania. Electronic address: .
Mihai CT; Advanced Centre for Research-Development in Experimental Medicine, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700115, Romania; Department of Experimental and Applied Biology, NIRDBS - Institute of Biological Research Iasi, Lascar Catargi 47, Iasi 700107, Romania. Electronic address: .
Serban AM; Faculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700115, Romania; Natural Polymers, Bioactive and Biocompatible Materials Laboratory, Petru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487, Iasi, Romania. Electronic address: .
Ursachi VC; Faculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700115, Romania; Advanced Centre for Research-Development in Experimental Medicine, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700115, Romania. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2021 Oct 01; Vol. 188, pp. 82-93. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Chitosan/*chemistry
Macromolecular Substances/*chemistry
Nanostructures/*chemistry
Neoplasms/*drug therapy
Biotin/chemistry ; Biotinylation ; Chitosan/therapeutic use ; Drug Delivery Systems ; Humans ; Macromolecular Substances/therapeutic use ; Molecular Imaging ; Nanostructures/therapeutic use ; Nanotechnology/trends
Czasopismo naukowe
Tytuł:
A Supramolecular Antidote to Macromolecular Toxins Prepared through Coassembly of Macrocyclic Amphiphiles.
Autorzy:
Pan YC; College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
Yue YX; College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
Hu XY; College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
Li HB; College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
Guo DS; College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
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Źródło:
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2021 Oct; Vol. 33 (40), pp. e2104310. Date of Electronic Publication: 2021 Aug 21.
Typ publikacji:
Journal Article
MeSH Terms:
Antidotes/*chemistry
Macromolecular Substances/*chemistry
Melitten/*chemistry
Animals ; Antidotes/metabolism ; Antidotes/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/pharmacology ; Cell Membrane/chemistry ; Cell Survival/drug effects ; Cyclodextrins/chemistry ; HEK293 Cells ; Hemolysis/drug effects ; Humans ; Liver/drug effects ; Liver/pathology ; Macromolecular Substances/metabolism ; Melitten/metabolism ; Melitten/pharmacology ; Mice ; Spider Venoms/chemistry ; Spider Venoms/pharmacology
Czasopismo naukowe
Tytuł:
Measuring in vivo protein turnover and exchange in yeast macromolecular assemblies.
Autorzy:
Hakhverdyan Z; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA.
Molloy KR; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY 10065, USA.
Subbotin RI; Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY 10065, USA.
Fernandez-Martinez J; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA.
Chait BT; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA.
Rout MP; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065, USA.
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Źródło:
STAR protocols [STAR Protoc] 2021 Sep 08; Vol. 2 (3), pp. 100800. Date of Electronic Publication: 2021 Sep 08 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Macromolecular Substances*/analysis
Macromolecular Substances*/chemistry
Macromolecular Substances*/metabolism
Saccharomyces cerevisiae Proteins*/analysis
Saccharomyces cerevisiae Proteins*/chemistry
Saccharomyces cerevisiae Proteins*/metabolism
Chromatography, Affinity/*methods
Proteomics/*methods
Isotope Labeling ; Proteolysis
Czasopismo naukowe
Tytuł:
Genesis of Neurotoxic Hybrid Nanofibers from the Coassembly of Aromatic Amino Acids.
Autorzy:
Anand BG; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Prajapati KP; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Ansari M; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Yadav DK; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Temgire M; Department of Chemical Engineering, Indian Institution of Technology Bombay, Powai, Mumbai 400076, India.
Kar K; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
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Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Aug 11; Vol. 13 (31), pp. 36722-36736. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji:
Journal Article
MeSH Terms:
Amino Acids, Aromatic/*toxicity
Macromolecular Substances/*toxicity
Nanofibers/*toxicity
Amino Acids, Aromatic/chemistry ; Amino Acids, Aromatic/metabolism ; Amyloidogenic Proteins/metabolism ; Cell Line, Tumor ; Cytochromes c/metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Insulin/metabolism ; Macromolecular Substances/chemistry ; Macromolecular Substances/metabolism ; Molecular Dynamics Simulation ; Myoglobin/metabolism ; Nanofibers/chemistry ; Protein Multimerization/drug effects ; Serum Albumin/metabolism
Czasopismo naukowe
Tytuł:
Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*.
Autorzy:
Melidis L; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hill HJ; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Coltman NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Davies SP; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Winczura K; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Chauhan T; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Craig JS; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Garai A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hooper CAJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Egan RT; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
McKeating JA; Nuffield Department of Medicine & Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), Oxford University, Oxford, OX3 7BN, UK.
Hodges NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Stamataki Z; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Grzechnik P; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hannon MJ; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Aug 09; Vol. 60 (33), pp. 18144-18151. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
5' Untranslated Regions*
Antiviral Agents/*pharmacology
Macromolecular Substances/*pharmacology
RNA/*metabolism
SARS-CoV-2/*drug effects
Virus Replication/*drug effects
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/metabolism ; Chlorocebus aethiops ; Coordination Complexes/chemistry ; Coordination Complexes/metabolism ; Coordination Complexes/pharmacology ; Genome, Viral/drug effects ; Macromolecular Substances/chemistry ; Macromolecular Substances/metabolism ; Metals, Heavy/chemistry ; Molecular Dynamics Simulation ; RNA/genetics ; SARS-CoV-2/chemistry ; Vero Cells
Czasopismo naukowe

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