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Wyszukujesz frazę ""mast cell"" wg kryterium: Temat


Tytuł :
A case of aleukemic mast cell leukemia with an underlying myeloproliferative neoplasm: Morphological and molecular characteristics of a highly aggressive disease.
Autorzy :
Loscocco GG; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.
Mannelli F; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.
Mannelli L; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.; Doctorate School GEnoMEC, University of Siena, Siena, Italy.
Vergoni F; Department of Surgery and Translational Medicine, Division of Pathology, University of Florence, Florence, Italy.
Gesullo F; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.
Rotunno G; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.
Guglielmelli P; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.
Vannucchi AM; CRIMM, Centro di Ricerca e Innovazione per le Malattie Mieloproliferative, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, DenoThe Excellence Center, Florence, Italy.
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Źródło :
American journal of hematology [Am J Hematol] 2020 Dec; Vol. 95 (12), pp. 1622-1624. Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Mast-Cell*/blood
Leukemia, Mast-Cell*/genetics
Leukemia, Mast-Cell*/pathology
Leukemia, Mast-Cell*/therapy
Mutation*
Myeloproliferative Disorders*/blood
Myeloproliferative Disorders*/genetics
Myeloproliferative Disorders*/pathology
Myeloproliferative Disorders*/therapy
Neoplasm Proteins*/blood
Neoplasm Proteins*/genetics
Chromosomes, Human/*genetics
Aged ; Humans ; Male
Czasopismo naukowe
Tytuł :
Injectable treatment for mast cell tumours in dogs.
Źródło :
The Veterinary record [Vet Rec] 2020 Oct 03; Vol. 187 (7), pp. e56. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Wiadomości
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Dog Diseases/*drug therapy
Mast-Cell Sarcoma/*veterinary
Skin Neoplasms/*veterinary
Animals ; Dogs ; Injections/veterinary ; Mast-Cell Sarcoma/drug therapy ; Skin Neoplasms/drug therapy
Periodyk
Tytuł :
Mast cell sarcoma with concurrent mast cell leukaemia.
Autorzy :
Raymond LM; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
Funk T; Department of Dermatology, Oregon Health and Science University, Portland, OR, USA.
Braziel RM; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
Fan G; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
Gatter K; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
Loriaux M; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
Dunlap J; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
Raess PW; Department of Pathology, Oregon Health and Science University, Portland, OR, USA.
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Źródło :
British journal of haematology [Br J Haematol] 2020 May; Vol. 189 (4), pp. e160-e164. Date of Electronic Publication: 2020 Apr 03.
Typ publikacji :
Letter
MeSH Terms :
Leukemia, Mast-Cell/*diagnosis
Mast-Cell Sarcoma/*diagnosis
Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Humans ; Leukemia, Mast-Cell/pathology ; Mast-Cell Sarcoma/pathology ; Middle Aged ; Young Adult
Opinia redakcyjna
Tytuł :
Siglec-7, a target for novel therapeutical approaches of Systemic Mastocytosis.
Autorzy :
Maggi E; Department of Immunology, IRCCS Bambino Gesù Children's Hospital, 00146, Roma, Italy.
Moretta L; Department of Immunology, IRCCS Bambino Gesù Children's Hospital, 00146, Roma, Italy. Electronic address: .
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Źródło :
Pharmacological research [Pharmacol Res] 2020 Aug; Vol. 158, pp. 104731. Date of Electronic Publication: 2020 Feb 29.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Leukemia, Mast-Cell*
Mastocytosis, Systemic*
Humans ; Mast Cells ; Sialic Acid Binding Immunoglobulin-like Lectins
Raport
Tytuł :
Activation of Siglec-7 results in inhibition of in vitro and in vivo growth of human mast cell leukemia cells.
Autorzy :
Landolina N; Pharmacology & Experimental Therapeutics Unit, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Zaffran I; Pharmacology & Experimental Therapeutics Unit, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Smiljkovic D; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.
Serrano-Candelas E; Biochemistry Unit, Biomedicine Department, Faculty of Medicine, University of Barcelona, Barcelona, Spain; Laboratory of Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain.
Schmiedel D; The Lautenberg Center for General and Tumor Immunology, The Hebrew University Hadassah Medical School, IMRIC, Jerusalem, Israel.
Friedman S; Pharmacology & Experimental Therapeutics Unit, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Arock M; Biological Haematology Department, Pitié-Salpêtrière Hospital, Paris, France.
Hartmann K; Department of Dermatology, University of Luebeck, Luebeck, Germany.
Pikarsky E; The Lautenberg Center for General and Tumor Immunology, The Hebrew University Hadassah Medical School, IMRIC, Jerusalem, Israel.
Mandelboim O; The Lautenberg Center for General and Tumor Immunology, The Hebrew University Hadassah Medical School, IMRIC, Jerusalem, Israel.
Martin M; Biochemistry Unit, Biomedicine Department, Faculty of Medicine, University of Barcelona, Barcelona, Spain; Laboratory of Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain.
Valent P; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Austria.
Levi-Schaffer F; Pharmacology & Experimental Therapeutics Unit, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel. Electronic address: .
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Źródło :
Pharmacological research [Pharmacol Res] 2020 Aug; Vol. 158, pp. 104682. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lectins/*agonists
Leukemia, Mast-Cell/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Animals ; Antibodies, Monoclonal/therapeutic use ; Antigens, Differentiation, Myelomonocytic ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Genes, src/drug effects ; Humans ; Leukemia, Mast-Cell/pathology ; Lymphoma, B-Cell/drug therapy ; Lymphoma, B-Cell/pathology ; Male ; Mastocytosis/drug therapy ; Mice ; Mice, SCID ; Middle Aged ; Phosphorylation ; Protein Tyrosine Phosphatase, Non-Receptor Type 6/drug effects ; Proto-Oncogene Proteins c-kit/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Systemic mastocytosis in adults: 2021 Update on diagnosis, risk stratification and management.
Autorzy :
Pardanani A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Apr 01; Vol. 96 (4), pp. 508-525. Date of Electronic Publication: 2021 Feb 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mastocytosis, Systemic*/diagnosis
Mastocytosis, Systemic*/drug therapy
Mastocytosis, Systemic*/epidemiology
Mastocytosis, Systemic*/genetics
Adult ; Algorithms ; Animals ; Bone Marrow/pathology ; Disease Management ; Disease Models, Animal ; Drugs, Investigational/therapeutic use ; Gain of Function Mutation ; Hematologic Neoplasms/epidemiology ; Humans ; Hydroxyurea/therapeutic use ; Interleukin-2 Receptor alpha Subunit/analysis ; Kaplan-Meier Estimate ; Leukemia, Mast-Cell/epidemiology ; Leukemia, Mast-Cell/etiology ; Mast Cells/chemistry ; Mast Cells/pathology ; Mice ; Mice, Transgenic ; Mutation, Missense ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-kit/genetics ; Risk Assessment ; Tryptases/blood
Czasopismo naukowe
Tytuł :
Treating the locoregional lymph nodes with radiation and/or surgery significantly improves outcome in dogs with high-grade mast cell tumours.
Autorzy :
Mendez SE; University of Pennsylvania, Department of Clinical Sciences & Advanced Medicine, Philadelphia, PA.
Drobatz KJ; University of Pennsylvania, Department of Clinical Sciences & Advanced Medicine, Philadelphia, PA.
Duda LE; University of Pennsylvania, Department of Clinical Sciences & Advanced Medicine, Philadelphia, PA.; University of Pennsylvania, Penn Vet Cancer Center, Philadelphia, Pennsylvania.
White P; The Oncology Service, Leesburg, Virginia.
Kubicek L; Angell Animal Medical Center, Boston, Massachusetts.
Sorenmo KU; University of Pennsylvania, Penn Vet Cancer Center, Philadelphia, Pennsylvania.; University of Pennsylvania, Department of Biomedical Sciences, Philadelphia, Pennsylvania.
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Źródło :
Veterinary and comparative oncology [Vet Comp Oncol] 2020 Jun; Vol. 18 (2), pp. 239-246. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Dog Diseases/*radiotherapy
Lymph Nodes/*pathology
Lymph Nodes/*surgery
Mast-Cell Sarcoma/*veterinary
Neoplasm Recurrence, Local/*veterinary
Animals ; Antineoplastic Agents/therapeutic use ; Dog Diseases/pathology ; Dog Diseases/prevention & control ; Dogs ; Female ; Lymph Nodes/radiation effects ; Lymphatic Metastasis/prevention & control ; Male ; Mast-Cell Sarcoma/pathology ; Mast-Cell Sarcoma/radiotherapy ; Neoplasm Recurrence, Local/prevention & control ; Neoplasm Recurrence, Local/radiotherapy ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Comparison table: Some nasal sprays for allergic rhinitis.
Źródło :
The Medical letter on drugs and therapeutics [Med Lett Drugs Ther] 2021 Apr 19; Vol. 63 (1622), pp. e66-e71. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anti-Allergic Agents/*administration & dosage
Rhinitis, Allergic/*drug therapy
Anti-Allergic Agents/pharmacology ; Cholinergic Antagonists/administration & dosage ; Glucocorticoids/administration & dosage ; Histamine H1 Antagonists, Non-Sedating/administration & dosage ; Humans ; Mast Cell Stabilizers/administration & dosage ; Nasal Sprays
Czasopismo naukowe
Tytuł :
Phosphorylated KIT as a predictor of outcome in canine mast cell tumours treated with toceranib phosphate or vinblastine.
Autorzy :
Thamm DH; Cell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, Colorado.; Flint Animal Cancer Center, College of Veterinary Medicine and Biosciences, Colorado State University, Fort Collins, Colorado.
Weishaar KM; Flint Animal Cancer Center, College of Veterinary Medicine and Biosciences, Colorado State University, Fort Collins, Colorado.
Charles JB; Flint Animal Cancer Center, College of Veterinary Medicine and Biosciences, Colorado State University, Fort Collins, Colorado.
Ehrhart EJ 3rd; Cell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, Colorado.; Flint Animal Cancer Center, College of Veterinary Medicine and Biosciences, Colorado State University, Fort Collins, Colorado.; Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biosciences, Colorado State University, Fort Collins, Colorado.
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Źródło :
Veterinary and comparative oncology [Vet Comp Oncol] 2020 Jun; Vol. 18 (2), pp. 169-175. Date of Electronic Publication: 2019 Oct 21.
Typ publikacji :
Clinical Trial, Veterinary; Journal Article; Multicenter Study
MeSH Terms :
Dog Diseases/*drug therapy
Indoles/*therapeutic use
Mast-Cell Sarcoma/*veterinary
Proto-Oncogene Proteins c-kit/*metabolism
Pyrroles/*therapeutic use
Skin Neoplasms/*veterinary
Vinblastine/*therapeutic use
Animals ; Antineoplastic Agents/therapeutic use ; Dog Diseases/pathology ; Dogs ; Gene Expression Regulation, Neoplastic/drug effects ; Mast-Cell Sarcoma/drug therapy ; Phosphorylation ; Prospective Studies ; Proto-Oncogene Proteins c-kit/genetics ; Skin Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
A systematic review of surgical margins utilized for removal of cutaneous mast cell tumors in dogs.
Autorzy :
Selmic LE; Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, 601 Vernon L Tharp St, Columbus, OH, 43221, USA. .
Ruple A; Department of Public Health, Purdue University, 725 Harrison Street, West Lafayette, IN, 47906, USA.
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Źródło :
BMC veterinary research [BMC Vet Res] 2020 Jan 06; Vol. 16 (1), pp. 5. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Margins of Excision*
Dog Diseases/*surgery
Mast-Cell Sarcoma/*veterinary
Skin Neoplasms/*veterinary
Animals ; Dogs ; Mast-Cell Sarcoma/surgery ; Neoplasm Recurrence, Local/prevention & control ; Neoplasm Recurrence, Local/veterinary ; Skin Neoplasms/surgery ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A case of aggressive systemic mastocytosis with bulky lymphadenopathy showing response to midostaurin.
Autorzy :
Sciumè, Mariarita (AUTHOR)
Serpenti, Fabio (AUTHOR)
Muratori, Simona (AUTHOR)
Pravettoni, Valerio (AUTHOR)
Ulivieri, Fabio Massimo (AUTHOR)
Croci, Giorgio Alberto (AUTHOR)
Migliorini, Anna Chiara (AUTHOR)
Esposito, Andrea (AUTHOR)
Goldaniga, Maria Cecilia (AUTHOR)
Saporiti, Giorgia Natascia (AUTHOR)
Galassi, Giulia (AUTHOR)
Baldini, Luca (AUTHOR)
Onida, Francesco (AUTHOR)
Grifoni, Federica Irene (AUTHOR)
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Źródło :
Clinical Case Reports. Feb2021, Vol. 9 Issue 2, p978-982. 5p.
Czasopismo naukowe
Tytuł :
COMPARATIVE EVALUATION OF THE CYTOLOGICAL, HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL FINDINGS OF CANINE CUTANEOUS AND SUBCUTANEOUS MASSES.
Autorzy :
Volkan, IPEK
Taci, CANGUL I.
Ahmet, AKKOC
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Alternatywny tytuł :
UPOREDNO ISPITIVANJE CITOLOŠKIH, HISTOPATOLOŠKIH I IMUNOHISTOHEMIJSKIH METODA DIJAGNOSTIKE KUTANIH I SUPKUTANIH MASA KOD PASA.
Źródło :
Acta Veterinaria. 2021, Vol. 71 Issue 1, p61-84. 24p.
Czasopismo naukowe
Tytuł :
Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL.
Autorzy :
Jain P; Department of Lymphoma and Myeloma.; Division of Cancer Medicine.
Zhang S; Department of Genomic Medicine.
Kanagal-Shamanna R; Department of Hematopathology.
Ok CY; Department of Hematopathology.
Nomie K; Department of Lymphoma and Myeloma.
Gonzalez GN; Department of Biostatistics.
Gonzalez-Pagan O; Division of Cancer Medicine.
Hill HA; Department of Lymphoma and Myeloma.
Lee HJ; Department of Lymphoma and Myeloma.
Fayad L; Department of Lymphoma and Myeloma.
Westin J; Department of Lymphoma and Myeloma.
Nastoupil L; Department of Lymphoma and Myeloma.
Hagemeister F; Department of Lymphoma and Myeloma.
Chen W; Department of Lymphoma and Myeloma.
Oriabure O; Department of Lymphoma and Myeloma.
Badillo M; Department of Lymphoma and Myeloma.
Jiang C; Department of Lymphoma and Myeloma.
Yixin Y; Department of Lymphoma and Myeloma.
Li S; Department of Genomic Medicine.
Tang G; Department of Genomic Medicine.
Yin CC; Department of Genomic Medicine.
Patel KP; Department of Genomic Medicine.
Medeiros LJ; Department of Genomic Medicine.
Nair R; Department of Lymphoma and Myeloma.
Ahmed S; Department of Lymphoma and Myeloma.
Iyer SP; Department of Lymphoma and Myeloma.
Thirumurthi S; Department of Gastroenterology.
Champlin R; Department of Stem Cell Transplantation and Cellular Therapy.
Xu G; Department of Nuclear Medicine.
Tinsu P; Department of Imaging Physics, and.
Santos D; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Wang R; Department of Genomic Medicine.
Han G; Department of Genomic Medicine.
Zhang J; Department of Genomic Medicine.
Song X; Department of Genomic Medicine.
Neelapu S; Department of Lymphoma and Myeloma.
Romaguera J; Department of Lymphoma and Myeloma.
Futreal A; Department of Genomic Medicine.
Flowers C; Department of Lymphoma and Myeloma.
Fowler N; Department of Lymphoma and Myeloma.
Wang L; Department of Genomic Medicine.
Wang ML; Department of Lymphoma and Myeloma.; Department of Stem Cell Transplantation and Cellular Therapy.
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Źródło :
Blood advances [Blood Adv] 2020 Mar 24; Vol. 4 (6), pp. 1038-1050.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukemia, Mast-Cell*
Lymphoma, Mantle-Cell*/diagnosis
Lymphoma, Mantle-Cell*/genetics
Adult ; Aged ; DNA Helicases ; Genomics ; Humans ; Mutation ; Nuclear Proteins ; Prognosis ; Transcription Factors
Czasopismo naukowe
Tytuł :
Recent advances in the understanding and therapeutic management of mastocytosis.
Autorzy :
Rossignol J; French Reference Center for Mastocytosis (CEREMAST), Necker Children's Hospital, APHP, Paris, France.
Polivka L; Department of Hematology, Gustave Roussy Institute, Paris-Saclay University, Villejuif, France.
Maouche-Chrétien L; Imagine Institute, Paris University, INSERM U 1183, Paris, France.
Frenzel L; Department of Dermatology, Necker Children's Hospital, APHP, Paris, France.
Dubreuil P; Department of Hematology, Necker Children's Hospital, APHP, Paris, France.
Hermine O; Centre de Recherche en Cancérologie de Marseille, Inserm U1068, Marseille, France.
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Źródło :
F1000Research [F1000Res] 2019 Nov 22; Vol. 8. Date of Electronic Publication: 2019 Nov 22 (Print Publication: 2019).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Leukemia, Mast-Cell*
Mastocytosis*
Humans ; Mutation ; Proto-Oncogene Proteins c-kit ; Quality of Life
Czasopismo naukowe
Tytuł :
Mast Cell Degranulation Increases Mouse Mast Cell Protease 4-Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin I.
Autorzy :
Vincent L; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
Lapointe C; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
Lo M; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
Gagnon H; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
Pejler G; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
Takai S; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
Day R; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.).
D'Orléans-Juste P; Department of Pharmacology and Physiology, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada (L.V., C.L., M.L., P.D.-J.); PhenoSwitch Bioscience Inc., Sherbrooke, Quebec, Canada (H.G.); Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden (G.P.); Department of Innovative Medicine, Osaka Medical College, Osaka, Japan (S.T.); and Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, Quebec, Canada (R.D.) .
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Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2021 Feb; Vol. 376 (2), pp. 213-221. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Pressure*
Cell Degranulation*
Angiotensin I/*pharmacology
Endothelin-1/*pharmacology
Mast Cells/*physiology
Serine Endopeptidases/*metabolism
Animals ; Cells, Cultured ; Chymases/antagonists & inhibitors ; Cromolyn Sodium/pharmacology ; Enzyme Inhibitors/pharmacology ; Male ; Mast Cell Stabilizers/pharmacology ; Mast Cells/drug effects ; Mast Cells/metabolism ; Mice ; Mice, Inbred C57BL ; Peritoneum/cytology ; Serine Endopeptidases/genetics ; Sulfonamides/pharmacology ; Thiophenes/pharmacology
Czasopismo naukowe
Tytuł :
The upregulation of Pim kinases is essential in coordinating the survival, proliferation, and migration of KIT D816V-mutated neoplastic mast cells.
Autorzy :
Park H; Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Kim D; Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Koh Y; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, 03080, Republic of Korea.
Yoon SS; Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, 03080, Republic of Korea. Electronic address: .
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Źródło :
Leukemia research [Leuk Res] 2019 Aug; Vol. 83, pp. 106166. Date of Electronic Publication: 2019 Jun 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Movement*
Cell Proliferation*
Gene Expression Regulation, Enzymologic*
Gene Expression Regulation, Leukemic*
MAP Kinase Signaling System*
Mutation, Missense*
Up-Regulation*
Leukemia, Mast-Cell/*enzymology
Proto-Oncogene Proteins c-kit/*biosynthesis
Proto-Oncogene Proteins c-pim-1/*biosynthesis
Amino Acid Substitution ; Cell Line, Tumor ; Cell Survival ; Humans ; Leukemia, Mast-Cell/genetics ; Leukemia, Mast-Cell/pathology ; Proto-Oncogene Proteins c-kit/genetics ; Proto-Oncogene Proteins c-pim-1/genetics
Czasopismo naukowe

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