Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""melanoma"" wg kryterium: Temat


Tytuł :
Bromodomain-containing protein 4 inhibitor JQ1 promotes melanoma cell apoptosis by regulating mitochondrial dynamics.
Autorzy :
Li L; Department of Otorhinolaryngology-Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun, China.; Department of Pathophysiology, Prostate Diseases Prevention and Treatment Research Center, College of Basic Medical Science, Jilin University, Changchun, China.
Meng Y; Department of Pathophysiology, Prostate Diseases Prevention and Treatment Research Center, College of Basic Medical Science, Jilin University, Changchun, China.
Wu X; Department of Pathophysiology, Prostate Diseases Prevention and Treatment Research Center, College of Basic Medical Science, Jilin University, Changchun, China.
Li J; Department of Pathophysiology, Prostate Diseases Prevention and Treatment Research Center, College of Basic Medical Science, Jilin University, Changchun, China.
Sun Y; Department of Otorhinolaryngology-Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun, China.
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2021 Oct; Vol. 112 (10), pp. 4013-4025. Date of Electronic Publication: 2021 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*physiology
Azepines/*pharmacology
Cell Cycle Proteins/*antagonists & inhibitors
Melanoma/*metabolism
Mitochondria/*drug effects
Skin Neoplasms/*metabolism
Transcription Factors/*antagonists & inhibitors
Triazoles/*pharmacology
AMP-Activated Protein Kinases/drug effects ; AMP-Activated Protein Kinases/metabolism ; Apoptosis/drug effects ; Cell Cycle Proteins/metabolism ; Cell Respiration/drug effects ; Dynamins/drug effects ; Dynamins/metabolism ; Electron Transport Chain Complex Proteins/drug effects ; Electron Transport Chain Complex Proteins/metabolism ; Energy Metabolism/drug effects ; Enzyme Activation/drug effects ; Female ; Fusion Regulatory Protein-1/metabolism ; Humans ; Melanoma/pathology ; Melanoma, Experimental/drug therapy ; Melanoma, Experimental/metabolism ; Melanoma, Experimental/pathology ; Mitochondria/metabolism ; Oxidative Stress/drug effects ; Protein Subunits/drug effects ; Protein Subunits/metabolism ; Proto-Oncogene Proteins c-myc/metabolism ; Reactive Oxygen Species/metabolism ; Skin Neoplasms/pathology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
The receptor for advanced glycation endproducts (RAGE) decreases survival of tumor-bearing mice by enhancing the generation of lung metastasis-associated myeloid-derived suppressor cells.
Autorzy :
Wuren T; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA.
Huecksteadt T; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT 84132, USA; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.
Beck E; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT 84132, USA; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.
Warren K; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT 84132, USA; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.
Hoidal J; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT 84132, USA; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.
Ostrand-Rosenberg S; Divisions of Microbiology and Immunology, Department of Pathology, University of Utah, Huntsman Cancer Institute, Salt Lake City, UT 84132, USA.
Sanders K; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT 84132, USA; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA. Electronic address: .
Pokaż więcej
Źródło :
Cellular immunology [Cell Immunol] 2021 Jul; Vol. 365, pp. 104379. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Lung/*pathology
Melanoma/*metabolism
Myeloid-Derived Suppressor Cells/*immunology
Neoplasms, Experimental/*metabolism
Receptor for Advanced Glycation End Products/*metabolism
Animals ; Calgranulin A/metabolism ; Calgranulin B/metabolism ; Cell Differentiation ; Humans ; Immune Tolerance ; Melanoma/immunology ; Melanoma, Experimental ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/metabolism ; Neoplasm Metastasis ; Neoplasms, Experimental/immunology ; Receptor for Advanced Glycation End Products/genetics ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Dermal melanocytic tumor with CRTC1-TRIM11 fusion: Report of two additional cases with review of the literature of an emerging entity.
Autorzy :
Parra O; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Bridge JA; Division of Molecular Pathology, The Translational Genomics Research Institute/Ashion, Phoenix, Arizona, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Busam KJ; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Shalin SC; Department of Pathology and Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Linos K; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Pokaż więcej
Źródło :
Journal of cutaneous pathology [J Cutan Pathol] 2021 Jul; Vol. 48 (7), pp. 915-924. Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Dermis/*pathology
Melanocytes/*metabolism
Melanoma/*pathology
Transcription Factors/*metabolism
Tripartite Motif Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Adult ; Aged ; Aged, 80 and over ; Child ; Female ; Humans ; Immunohistochemistry/methods ; MART-1 Antigen/metabolism ; Melanocytes/pathology ; Melanoma/surgery ; Microphthalmia-Associated Transcription Factor/metabolism ; Middle Aged ; S100 Proteins/metabolism ; SOXE Transcription Factors/metabolism ; Treatment Outcome ; gp100 Melanoma Antigen/metabolism
Czasopismo naukowe
Tytuł :
Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression.
Autorzy :
Tengesdal IW; Department of Medicine, University of Colorado Denver, Aurora, CO, United States.; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, Netherlands.
Dinarello A; Department of Medicine, University of Colorado Denver, Aurora, CO, United States.; Dipartimento di Biologia, Università degli Studi di Padova, Padova, Italy.
Powers NE; Department of Medicine, University of Colorado Denver, Aurora, CO, United States.
Burchill MA; Department of Medicine, University of Colorado Denver, Aurora, CO, United States.
Joosten LAB; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, Netherlands.
Marchetti C; Department of Medicine, University of Colorado Denver, Aurora, CO, United States.
Dinarello CA; Department of Medicine, University of Colorado Denver, Aurora, CO, United States.; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, Netherlands.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2021 Aug 31; Vol. 12, pp. 661323. Date of Electronic Publication: 2021 Aug 31 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-1beta/*immunology
Interleukin-6/*immunology
Melanoma/*immunology
Myeloid-Derived Suppressor Cells/*immunology
NLR Family, Pyrin Domain-Containing 3 Protein/*immunology
STAT3 Transcription Factor/*immunology
Animals ; Cell Line, Tumor ; Humans ; Immune Tolerance/drug effects ; Immune Tolerance/immunology ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Melanoma/metabolism ; Melanoma/pathology ; Melanoma, Experimental/drug therapy ; Melanoma, Experimental/immunology ; Melanoma, Experimental/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Immunological ; Myeloid-Derived Suppressor Cells/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Nitriles/pharmacology ; Pyrazoles/pharmacology ; Pyrimidines/pharmacology ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Tumor Burden/drug effects ; Tumor Burden/immunology
Czasopismo naukowe
Tytuł :
Converting an Anti-Mouse CD4 Monoclonal Antibody into an scFv Positron Emission Tomography Imaging Agent for Longitudinal Monitoring of CD4 T Cells.
Autorzy :
Islam A; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.; Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway.
Pishesha N; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.; Society of Fellows, Harvard University, Cambridge, MA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA.
Harmand TJ; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.
Heston H; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.
Woodham AW; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.
Cheloha RW; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA.
Bousbaine D; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA.; Microbiology Graduate Program, Massachusetts Institute of Technology, Cambridge, MA.
Rashidian M; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA; and.; Department of Radiology, Harvard Medical School, Boston, MA.
Ploegh HL; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA; .; Department of Pediatrics, Harvard Medical School, Boston, MA.
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Sep 01; Vol. 207 (5), pp. 1468-1477. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CD4 Antigens/*immunology
CD4-Positive T-Lymphocytes/*immunology
Immunotherapy/*methods
Lymphocytes, Tumor-Infiltrating/*immunology
Melanoma/*therapy
Monitoring, Immunologic/*methods
Skin Neoplasms/*therapy
Animals ; Antibodies, Monoclonal/metabolism ; Diagnostic Imaging ; Female ; Immunologic Memory ; Melanoma, Experimental ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Positron-Emission Tomography ; Single-Chain Antibodies/metabolism
Czasopismo naukowe
Tytuł :
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function.
Autorzy :
Whiteside SK; Department of Pathology, University of Cambridge, Cambridge, UK.; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Grant FM; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Gyori DS; Department of Physiology, Semmelweis University, Budapest, Hungary.
Conti AG; Department of Pathology, University of Cambridge, Cambridge, UK.
Imianowski CJ; Department of Pathology, University of Cambridge, Cambridge, UK.; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Kuo P; Department of Pathology, University of Cambridge, Cambridge, UK.; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Nasrallah R; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Sadiyah F; Department of Pathology, University of Cambridge, Cambridge, UK.; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Lira SA; Mount Sinai School of Medicine, Immunology Institute, New York, NY, USA.
Tacke F; Department of Hepatology & Gastroenterology, Campus Virchow-Klinikum (CVK) and Campus Charité Mitte (CCM), Charité Universitätsmedizin Berlin, Berlin, Germany.
Eil RL; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Burton OT; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Dooley J; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Liston A; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Okkenhaug K; Department of Pathology, University of Cambridge, Cambridge, UK.
Yang J; Department of Pathology, University of Cambridge, Cambridge, UK.; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Roychoudhuri R; Department of Pathology, University of Cambridge, Cambridge, UK.; Immunology Programme, Babraham Research Campus, Babraham Institute, Cambridge, UK.
Pokaż więcej
Źródło :
Immunology [Immunology] 2021 Aug; Vol. 163 (4), pp. 512-520. Date of Electronic Publication: 2021 May 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma/*immunology
Colorectal Neoplasms/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Melanoma/*immunology
Receptors, CCR8/*metabolism
Skin Neoplasms/*immunology
T-Lymphocytes, Regulatory/*immunology
Animals ; Forkhead Transcription Factors/metabolism ; Humans ; Immune Tolerance ; Melanoma, Experimental ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, CCR8/genetics
Czasopismo naukowe
Tytuł :
Targeting STAT3 Abrogates Tim-3 Upregulation of Adaptive Resistance to PD-1 Blockade on Regulatory T Cells of Melanoma.
Autorzy :
Huang L; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Tongji University Cancer Center, Shanghai, China.
Xu Y; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Fang J; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Tongji University Cancer Center, Shanghai, China.
Liu W; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Tongji University Cancer Center, Shanghai, China.
Chen J; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Tongji University Cancer Center, Shanghai, China.
Liu Z; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Tongji University Cancer Center, Shanghai, China.
Xu Q; Department of Oncology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Tongji University Cancer Center, Shanghai, China.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2021 Apr 15; Vol. 12, pp. 654749. Date of Electronic Publication: 2021 Apr 15 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*/drug effects
Hepatitis A Virus Cellular Receptor 2/*genetics
Melanoma/*etiology
Melanoma/*metabolism
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
STAT3 Transcription Factor/*metabolism
T-Lymphocytes, Regulatory/*drug effects
T-Lymphocytes, Regulatory/*metabolism
Aged ; Animals ; Biomarkers, Tumor ; Databases, Genetic ; Disease Models, Animal ; Drug Resistance, Neoplasm/drug effects ; Female ; Gene Expression Profiling ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Immunohistochemistry ; Male ; Melanoma/pathology ; Melanoma/therapy ; Melanoma, Experimental ; Mice ; Middle Aged ; Programmed Cell Death 1 Receptor/metabolism ; STAT3 Transcription Factor/antagonists & inhibitors ; Signal Transduction/drug effects ; T-Lymphocytes, Regulatory/immunology
Czasopismo naukowe
Tytuł :
SIRT2 promotes murine melanoma progression through natural killer cell inhibition.
Autorzy :
Zhang M; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Acklin S; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Gillenwater J; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Du W; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Patra M; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Yu H; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Xu B; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
Yu J; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
Xia F; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2021 Jun 21; Vol. 11 (1), pp. 12988. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Immunomodulation*
Killer Cells, Natural/*immunology
Killer Cells, Natural/*metabolism
Melanoma/*etiology
Melanoma/*metabolism
Sirtuin 2/*metabolism
Animals ; Biomarkers ; Cell Line, Tumor ; Cell Movement ; Disease Progression ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Melanoma/pathology ; Melanoma, Experimental ; Mice ; Sirtuin 2/genetics ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy.
Autorzy :
Wang Y; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Gu T; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Tian X; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Li W; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Zhao R; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Yang W; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Gao Q; Department of Immunology, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, China.
Li T; Department of Immunology, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, China.
Shim JH; Department of Pharmacy, College of Pharmacy, Mokpo National University, Mokpo, South Korea.
Zhang C; Department of Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Liu K; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.
Lee MH; Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, China.; College of Korean Medicine, DongShin University, Naju, South Korea.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2021 May 14; Vol. 12, pp. 654463. Date of Electronic Publication: 2021 May 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B7-H1 Antigen/*metabolism
Carcinoma, Non-Small-Cell Lung/*immunology
Carcinoma, Non-Small-Cell Lung/*metabolism
Immune Checkpoint Inhibitors/*pharmacology
Melanoma/*immunology
Melanoma/*metabolism
Programmed Cell Death 1 Receptor/*metabolism
Animals ; B7-H1 Antigen/chemistry ; Cell Line ; Cytokines/metabolism ; Cytotoxicity, Immunologic ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Humans ; Immune Checkpoint Inhibitors/chemistry ; Immune Checkpoint Inhibitors/therapeutic use ; Lung Neoplasms/drug therapy ; Lung Neoplasms/immunology ; Lung Neoplasms/metabolism ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/immunology ; Melanoma/drug therapy ; Melanoma, Experimental ; Mice ; Models, Biological ; Molecular Structure ; Programmed Cell Death 1 Receptor/chemistry ; Protein Binding/drug effects ; Signal Transduction ; Structure-Activity Relationship ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Noninvasive, longitudinal imaging-based analysis of body adipose tissue and water composition in a melanoma mouse model and in immune checkpoint inhibitor-treated metastatic melanoma patients.
Autorzy :
Thaiss WM; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University, 72076, Tübingen, Germany.; Department of Diagnostic and Interventional Radiology, Eberhard Karls University, 72076, Tübingen, Germany.; Department of Nuclear Medicine, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Gatidis S; Department of Diagnostic and Interventional Radiology, Eberhard Karls University, 72076, Tübingen, Germany.; iFIT-Cluster of Excellence, Eberhard Karls University, 72076, Tübingen, Germany.
Sartorius T; German Center for Diabetes Research (DZD E.V.), Neuherberg, Germany.; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany.
Machann J; German Center for Diabetes Research (DZD E.V.), Neuherberg, Germany.; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany.; Section of Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Peter A; German Center for Diabetes Research (DZD E.V.), Neuherberg, Germany.; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany.; Department for Diagnostic Laboratory Medicine, Institute for Clinical Chemistry and Pathobiochemistry, University Hospital Tübingen, Tübingen, Germany.
Eigentler TK; Department of Dermatology, University Hospital Tübingen, Liebermeisterstreet 20, 72076, Tübingen, Germany.
Nikolaou K; Department of Diagnostic and Interventional Radiology, Eberhard Karls University, 72076, Tübingen, Germany.
Pichler BJ; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University, 72076, Tübingen, Germany.; iFIT-Cluster of Excellence, Eberhard Karls University, 72076, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) Partner Site Tübingen, 72076, Tübingen, Germany.
Kneilling M; Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University, 72076, Tübingen, Germany. .; iFIT-Cluster of Excellence, Eberhard Karls University, 72076, Tübingen, Germany. .; Department of Dermatology, University Hospital Tübingen, Liebermeisterstreet 20, 72076, Tübingen, Germany. .
Pokaż więcej
Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 May; Vol. 70 (5), pp. 1263-1275. Date of Electronic Publication: 2020 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue/*diagnostic imaging
Cachexia/*diagnosis
Magnetic Resonance Imaging/*methods
Melanoma/*diagnosis
Skin Neoplasms/*diagnosis
Adipose Tissue/chemistry ; Aged ; Animals ; Disease Models, Animal ; Female ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Male ; Melanoma/drug therapy ; Melanoma, Experimental ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Monitoring, Physiologic ; Neoplasm Metastasis ; Neoplasm Staging ; Skin Neoplasms/drug therapy ; Water/analysis
Czasopismo naukowe
Tytuł :
Phenolic Compounds in Prevention and Treatment of Skin Cancers: A Review.
Autorzy :
Gado F; Department of Pharmacy, University of Pisa, Pisa, Italy.
Digiacomo M; Department of Pharmacy, University of Pisa, Pisa, Italy.
Salsano JE; Department of Pharmacy, University of Pisa, Pisa, Italy.
Macchia M; Department of Pharmacy, University of Pisa, Pisa, Italy.
Manera C; Department of Pharmacy, University of Pisa, Pisa, Italy.
Pokaż więcej
Źródło :
Current medicinal chemistry [Curr Med Chem] 2021 Oct 25; Vol. 28 (33), pp. 6730-6752.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Melanoma*/drug therapy
Melanoma*/prevention & control
Skin Neoplasms*/drug therapy
Skin Neoplasms*/prevention & control
Humans ; Phenols/therapeutic use ; Skin ; Ultraviolet Rays
Czasopismo naukowe
Tytuł :
Melanoma of the Hands and Feet (With Reconstruction).
Autorzy :
Ruffolo AM; Division of Plastic Surgery, Southern Illinois University School of Medicine, 747 N Rutledge Street #3, Springfield, IL 62702, USA. Electronic address: .
Sampath AJ; Department of Internal Medicine, St. Louis University School of Medicine, 1201 S Grand Boulevard, St Louis, MO 63104, USA.
Kozlow JH; Section of Plastic and Reconstructive Surgery, University of Michigan School of Medicine, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Neumeister MW; Division of Plastic Surgery, Southern Illinois University School of Medicine, 747 N Rutledge Street #3, Springfield, IL 62702, USA.
Pokaż więcej
Źródło :
Clinics in plastic surgery [Clin Plast Surg] 2021 Oct; Vol. 48 (4), pp. 687-698. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Melanoma*/diagnosis
Melanoma*/surgery
Skin Neoplasms*/diagnosis
Skin Neoplasms*/surgery
Hand/surgery ; Humans ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Extirpative Considerations of Melanoma of the Head and Neck.
Autorzy :
Olla D; Institute for Plastic Surgery, Southern Illinois University, 747 North Rutledge Street #3, Springfield, IL 62702, USA. Electronic address: .
Tufaro AP; University Hospitals Cleveland Medical Center, 11100 Euclid Aveune, Suite 5206, Cleveland, OH 44106, USA.
Neumeister MW; Department of Surgery, The Elvin G Zook Endowed Chair - Institute for Plastic Surgery, Southern Illinois University, 747 North Rutledge Street #3, Springfield, IL 62702, USA.
Pokaż więcej
Źródło :
Clinics in plastic surgery [Clin Plast Surg] 2021 Oct; Vol. 48 (4), pp. 659-668.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Head and Neck Neoplasms*/epidemiology
Head and Neck Neoplasms*/surgery
Melanoma*/epidemiology
Melanoma*/surgery
Skin Neoplasms*/epidemiology
Skin Neoplasms*/surgery
Humans ; Lymph Node Excision ; Lymph Nodes ; Neck ; Retrospective Studies ; Sentinel Lymph Node Biopsy
Czasopismo naukowe
Tytuł :
Primary melanoma of the anorectal region: clinical and histopathological review of 17 cases. A retrospective cohort study.
Autorzy :
Kolosov A; Department of Abdominal and General Surgery and Oncology, National Cancer Institute, Vilnius, Lithuania.; Faculty of Mechanics, Department of Biomechanical Engineering, Vilnius Gediminas Technical University (Vilnius Tech, Vilnius, Lithuania.; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Leskauskaitė J; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.; National Center of Pathology, Affiliate of Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.
Dulskas A; Department of Abdominal and General Surgery and Oncology, National Cancer Institute, Vilnius, Lithuania.; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Pokaż więcej
Źródło :
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland [Colorectal Dis] 2021 Oct; Vol. 23 (10), pp. 2706-2713. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Anus Neoplasms*/diagnosis
Anus Neoplasms*/therapy
Melanoma*/diagnosis
Melanoma*/therapy
Rectal Neoplasms*/surgery
Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
Melanoma in Pregnancy and Pediatrics.
Autorzy :
Romanelli MR; Institute for Plastic Surgery, Southern Illinois University, 747 North Rutledge Street #3, Springfield, IL 62702, USA.
Mansour A; Southern Illinois University School of Medicine, 747 North Rutledge Street #3, Springfield, IL 62702, USA.
Topaz A; Institute for Plastic Surgery, Southern Illinois University, 747 North Rutledge Street #3, Springfield, IL 62702, USA.
Olla D; Institute for Plastic Surgery, Southern Illinois University, 747 North Rutledge Street #3, Springfield, IL 62702, USA. Electronic address: .
Neumeister MW; Department of Surgery, Institute for Plastic Surgery, Southern Illinois University, 747 North Rutledge Street #3, Springfield, IL 62702, USA.
Pokaż więcej
Źródło :
Clinics in plastic surgery [Clin Plast Surg] 2021 Oct; Vol. 48 (4), pp. 699-705.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Melanoma*/diagnosis
Melanoma*/epidemiology
Melanoma*/therapy
Pediatrics*
Skin Neoplasms*/diagnosis
Skin Neoplasms*/epidemiology
Skin Neoplasms*/surgery
Child ; Female ; Humans ; Incidence ; Neoplasm Staging ; Pregnancy
Czasopismo naukowe
Tytuł :
Mucosal Melanoma.
Autorzy :
Olla D; Institute for Plastic Surgery, Southern Illinois University, 747 N Rutledge Street #3, Springfield, IL 62702, USA. Electronic address: .
Neumeister MW; Department of Surgery, The Elvin G Zook Endowed Chair - Institute for Plastic Surgery, Southern Illinois University, 747 N Rutledge Street #3, Springfield, IL 62702, USA.
Pokaż więcej
Źródło :
Clinics in plastic surgery [Clin Plast Surg] 2021 Oct; Vol. 48 (4), pp. 707-711. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Head and Neck Neoplasms*/diagnosis
Head and Neck Neoplasms*/surgery
Melanoma*/diagnosis
Melanoma*/therapy
Humans ; Mucous Membrane ; Prognosis
Czasopismo naukowe
Tytuł :
Tumor cell-intrinsic RIG-I signaling governs synergistic effects of immunogenic cancer therapies and checkpoint inhibitors in mice.
Autorzy :
Poeck H; Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.; National Centre for Tumor Diseases WERA, Germany.; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany.
Wintges A; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.
Dahl S; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.
Bassermann F; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany.
Haas T; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.
Heidegger S; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany.
Pokaż więcej
Źródło :
European journal of immunology [Eur J Immunol] 2021 Jun; Vol. 51 (6), pp. 1531-1534. Date of Electronic Publication: 2021 Apr 05.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Azacitidine/*therapeutic use
Immune Checkpoint Inhibitors/*therapeutic use
Immunotherapy/*methods
Melanoma/*immunology
Receptors, Cell Surface/*metabolism
Animals ; Chemoradiotherapy ; Disease Models, Animal ; Drug Synergism ; Humans ; Melanoma/therapy ; Melanoma, Experimental ; Mice ; Mice, Inbred C57BL ; Receptors, Cell Surface/genetics ; Signal Transduction ; Treatment Outcome
Raport
Tytuł :
Decursinol Angelate Arrest Melanoma Cell Proliferation by Initiating Cell Death and Tumor Shrinkage via Induction of Apoptosis.
Autorzy :
Chang SN; Advanced Bio Convergence Center (ABCC), Pohang Technopark Foundation, Pohang, Gyeongbuk 37668, Korea.; Department of Biotechnology, Daegu University, Gyeongsan, Gyeongbuk 38453, Korea.
Khan I; Department of Biotechnology, Daegu University, Gyeongsan, Gyeongbuk 38453, Korea.; The Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Kim CG; Advanced Bio Convergence Center (ABCC), Pohang Technopark Foundation, Pohang, Gyeongbuk 37668, Korea.
Park SM; Advanced Bio Convergence Center (ABCC), Pohang Technopark Foundation, Pohang, Gyeongbuk 37668, Korea.
Choi DK; New Drug Development Center, DGMIF, 88 Dongnae-ro, Dong-gu, Daegu 41061, Korea.
Lee H; New Drug Development Center, DGMIF, 88 Dongnae-ro, Dong-gu, Daegu 41061, Korea.
Hwang BS; Nakdonggang National Institute of Biological Resources, Sangju 37242, Korea.
Kang SC; Department of Biotechnology, Daegu University, Gyeongsan, Gyeongbuk 38453, Korea.
Park JG; Advanced Bio Convergence Center (ABCC), Pohang Technopark Foundation, Pohang, Gyeongbuk 37668, Korea.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 15; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Benzopyrans/*pharmacology
Butyrates/*pharmacology
Melanoma/*pathology
Skin Neoplasms/*pathology
Acetylcysteine/pharmacology ; Animals ; Antineoplastic Agents/pharmacology ; Autophagosomes/drug effects ; Autophagosomes/metabolism ; Benzopyrans/toxicity ; Butyrates/toxicity ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Male ; Melanoma, Experimental/pathology ; Mice, Inbred BALB C ; Mice, Nude ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondrial Membranes/drug effects ; Mitochondrial Membranes/metabolism ; Models, Biological ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model.
Autorzy :
Merino M; Department of Pharmaceutical Technology and Chemistry, School of Pharmacy, University of Navarra, 31008, Pamplona, Navarra, Spain.
Lozano T; Program of Immunology and Immunotherapy, CIMA-Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdisNA), Pamplona, Spain.
Casares N; Program of Immunology and Immunotherapy, CIMA-Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdisNA), Pamplona, Spain.
Lana H; Department of Pharmaceutical Technology and Chemistry, School of Pharmacy, University of Navarra, 31008, Pamplona, Navarra, Spain.
Troconiz IF; Department of Pharmaceutical Technology and Chemistry, School of Pharmacy, University of Navarra, 31008, Pamplona, Navarra, Spain.; Navarra Institute for Health Research (IdisNA), Pamplona, Spain.
Ten Hagen TLM; Laboratory of Experimental Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.
Kochan G; Navarra Institute for Health Research (IdisNA), Pamplona, Spain.; Department of Oncology, Navarrabiomed-Biomedical Research Centre, Pamplona, Spain.
Berraondo P; Program of Immunology and Immunotherapy, CIMA-Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research (IdisNA), Pamplona, Spain.
Zalba S; Department of Pharmaceutical Technology and Chemistry, School of Pharmacy, University of Navarra, 31008, Pamplona, Navarra, Spain. .; Navarra Institute for Health Research (IdisNA), Pamplona, Spain. .
Garrido MJ; Department of Pharmaceutical Technology and Chemistry, School of Pharmacy, University of Navarra, 31008, Pamplona, Navarra, Spain. .; Navarra Institute for Health Research (IdisNA), Pamplona, Spain. .
Pokaż więcej
Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Apr 13; Vol. 19 (1), pp. 102. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
B7-H1 Antigen/*metabolism
Doxorubicin/*pharmacology
Immunity/*drug effects
Liposomes/*immunology
Melanoma/*drug therapy
Animals ; Antibodies, Monoclonal/pharmacology ; Antineoplastic Agents, Immunological/pharmacology ; Cell Line, Tumor ; Disease Models, Animal ; Drug Liberation ; Drug Therapy ; Female ; Immunotherapy/methods ; Melanoma, Experimental/drug therapy ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Aberrant expression of HMB45 and negative PRAME expression in halo nevi.
Autorzy :
Ruby KN; Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Li Z; Biomedical Data Science Department, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Yan S; Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Pokaż więcej
Źródło :
Journal of cutaneous pathology [J Cutan Pathol] 2021 Apr; Vol. 48 (4), pp. 519-525. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Neoplasm/*metabolism
Nevus, Halo/*diagnosis
Nevus, Halo/*metabolism
gp100 Melanoma Antigen/*metabolism
Adolescent ; Adult ; Child ; Diagnosis, Differential ; Female ; Humans ; Male ; Melanocytes/metabolism ; Melanocytes/pathology ; Melanoma/diagnosis ; Melanoma/pathology ; Microscopy/methods ; Middle Aged ; Nevus/pathology ; Nevus, Halo/pathology ; Nevus, Halo/ultrastructure ; Nevus, Pigmented/pathology ; Retrospective Studies ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology ; Staining and Labeling/methods ; Young Adult
SCR Disease Name :
Melanoma, Cutaneous Malignant
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies