Temat: "metformin." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Metformin: A Dual-Role Player in Cancer Treatment and Prevention.
Autorzy:: Galal MA; Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.; Department of Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 1QU, UK.
Al-Rimawi M; Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Hajeer A; Medical School, University of Manchester, Manchester M14 4PX, UK.
Dahman H; Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Alouch S; Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Aljada A; Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 06; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Metformin*/pharmacology
Metformin*/therapeutic use
Diabetes Mellitus, Type 2*/drug therapy
Neoplasms*/drug therapy
Humans ; Cell Proliferation ; Chemotherapy, Adjuvant ; Hyperplasia

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Skocz do pozycji: 2.

Tytuł:: Metformin normalizes mitochondrial function to delay astrocyte senescence in a mouse model of Parkinson's disease through Mfn2-cGAS signaling.
Autorzy:: Wang M; Department of Geriatrics, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, People's Republic of China.
Tian T; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Zhou H; National Demonstration Center for Experimental Basic Medical Education, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Jiang SY; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Jiao YY; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Zhu Z; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China.
Xia J; Department of Orthopedics, Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, People's Republic of China. .
Ma JH; Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210000, Jiangsu, People's Republic of China. .
Du RH; Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology, Nanjing Medical University, Nanjing, 211166, Jiangsu, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2024 Apr 02; Vol. 21 (1), pp. 81. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*/metabolism
Metformin*/pharmacology
Metformin*/therapeutic use
Mice ; Animals ; Astrocytes/metabolism ; Dopaminergic Neurons ; Nucleotidyltransferases/metabolism ; Mitochondria/metabolism ; GTP Phosphohydrolases/genetics ; GTP Phosphohydrolases/metabolism ; GTP Phosphohydrolases/pharmacology

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Skocz do pozycji: 3.

Tytuł:: Metformin versus metformin plus pioglitazone on gonadal and metabolic profiles in normal-weight women with polycystic ovary syndrome: a single-center, open-labeled prospective randomized controlled trial.
Autorzy:: Zhao H; Department of Endocrinology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Wuxi, Jiangsu, 214000, PR China.; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
Zhang J; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
Xing C; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
Cheng X; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
He B; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China. .; Pokaż więcej
Źródło:: Journal of ovarian research [J Ovarian Res] 2024 Feb 19; Vol. 17 (1), pp. 42. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:: Randomized Controlled Trial; Journal Article
MeSH Terms:: Metformin*/pharmacology
Metformin*/therapeutic use
Polycystic Ovary Syndrome*/drug therapy
Female ; Humans ; Pioglitazone/therapeutic use ; Prospective Studies ; Testosterone ; Luteinizing Hormone ; Follicle Stimulating Hormone ; Anti-Mullerian Hormone ; Metabolome ; Glucose

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Skocz do pozycji: 4.

Tytuł:: Metformin Alters mRNA Expression of FOXP3 , RORC , and TBX21 and Modulates Gut Microbiota in COVID-19 Patients with Type 2 Diabetes.
Autorzy:: Petakh P; Department of Biochemistry and Pharmacology, Uzhhorod National University, 88000 Uzhhorod, Ukraine.; Department of Microbiology, Virology, and Immunology, I. Horbachevsky Ternopil National Medical University, 46001 Ternopil, Ukraine.
Kamyshna I; Department of Medical Rehabilitation, I. Horbachevsky Ternopil National Medical University, 46001 Ternopil, Ukraine.
Oksenych V; Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway.
Kamyshnyi O; Department of Microbiology, Virology, and Immunology, I. Horbachevsky Ternopil National Medical University, 46001 Ternopil, Ukraine.; Pokaż więcej
Źródło:: Viruses [Viruses] 2024 Feb 11; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 11.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/microbiology
Gastrointestinal Microbiome*/genetics
Metformin*/pharmacology
Metformin*/therapeutic use
Humans ; Forkhead Transcription Factors ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; RNA, Messenger

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Skocz do pozycji: 5.

Tytuł:: Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Autorzy:: Zunica ERM; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Heintz EC; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Dantas WS; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Hebert RC; Translational Physiology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Tanksley M; Sleep and Cardiometabolic Health Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Beyl RA; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Mader EC Jr; Louisiana State University Health Science Center, New Orleans, Louisiana, USA.
Kirwan JP; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Axelrod CL; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Singh P; Sleep and Cardiometabolic Health Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2024 Feb; Vol. 12 (3), pp. e15948.
Typ publikacji:: Randomized Controlled Trial; Journal Article
MeSH Terms:: Metformin*/pharmacology
Metformin*/therapeutic use
Diabetes Mellitus*
Sleep Apnea, Obstructive*/complications
Adult ; Humans ; Pilot Projects ; Blood Glucose/metabolism ; Insulin ; Glucose

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Skocz do pozycji: 6.

Tytuł:: Mechanistic Insights about Sorafenib-, Valproic Acid- and Metformin-Induced Cell Death in Hepatocellular Carcinoma.
Autorzy:: Franco-Juárez EX; Departamento de Biología Molecular, Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64720, Nuevo Leon, Mexico.; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza 66451, Nuevo Leon, Mexico.
González-Villasana V; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza 66451, Nuevo Leon, Mexico.
Camacho-Moll ME; Departamento de Biología Molecular, Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64720, Nuevo Leon, Mexico.
Rendón-Garlant L; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza 66451, Nuevo Leon, Mexico.
Ramírez-Flores PN; Departamento de Biología Molecular, Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64720, Nuevo Leon, Mexico.; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey 64710, Nuevo Leon, Mexico.
Silva-Ramírez B; Departamento de Inmunogenética, Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64720, Nuevo Leon, Mexico.
Peñuelas-Urquides K; Departamento de Biología Molecular, Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64720, Nuevo Leon, Mexico.
Cabello-Ruiz ED; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza 66451, Nuevo Leon, Mexico.
Castorena-Torres F; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey 64710, Nuevo Leon, Mexico.
Bermúdez de León M; Departamento de Biología Molecular, Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey 64720, Nuevo Leon, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 01; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/metabolism
Metformin*/pharmacology
Metformin*/therapeutic use
Humans ; Sorafenib/pharmacology ; Sorafenib/therapeutic use ; Valproic Acid/pharmacology ; Valproic Acid/therapeutic use ; Bevacizumab ; Cell Death

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Skocz do pozycji: 7.

Tytuł:: Metformin Loaded Zein Polymeric Nanoparticles to Augment Antitumor Activity against Ehrlich Carcinoma via Activation of AMPK Pathway: D-Optimal Design Optimization, In Vitro Characterization, and In Vivo Study.
Autorzy:: Elmahboub Y; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza 12585, Egypt.
Albash R; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza 12585, Egypt.
Magdy William M; Department of Biochemistry, Faculty of Pharmacy, October 6 University, Giza 12585, Egypt.
Rayan AH; Department of Medical Education, College of Medicine, AlMaarefa University, Diriyah, Riyadh 13713, Saudi Arabia.
Hamed NO; Department of Pharmaceutical Sciences, Faculty of Pharmacy, AlMaarefa University, Diriyah, Riyadh 13713, Saudi Arabia.
Ousman MS; Emergency Medical Services, College of Applied Sciences, AlMaarefa University, Diriyah, Riyadh 13713, Saudi Arabia.
Raslan NA; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt.; Clinical Pharmacy Program, College of Health Sciences and Nursing, Al-Rayan Colleges, Medina 42541, Saudi Arabia.
Mosallam S; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October 6 University, Giza 12585, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 03; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:: Journal Article
MeSH Terms:: Metformin*/pharmacology
Zein*
Carcinoma*
MicroRNAs*
Nanoparticles*
Animals ; Mice ; AMP-Activated Protein Kinases ; Polymers

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Skocz do pozycji: 8.

Tytuł:: A practical evidence-based approach to management of type 2 diabetes in children and young people (CYP): UK consensus.
Autorzy:: White B; University College London Hospitals NHS Foundation Trust, London, UK.
Ng SM; Mersey And West Lancashire Teaching Hospitals NHS Trust, Ormskirk, UK.
Agwu JC; Wye Valley NHS Trust, Hereford, UK.
Barrett TG; Birmingham Women's And Children NHS Foundation Trust, Birmingham, UK.
Birchmore N; Great Ormond Street Hospital For Children, NHS Foundation Trust, London, UK.
Kershaw M; Birmingham Women's And Children NHS Foundation Trust, Birmingham, UK.
Drew J; Nottingham University Hospitals NHS Foundation Trust, Nottingham, UK.
Kavvoura F; Royal Berkshire NHS Foundation Trust, Reading, UK.
Law J; Nottingham University Hospitals NHS Foundation Trust, Nottingham, UK.
Moudiotis C; Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.
Procter E; Nottingham University Hospitals NHS Foundation Trust, Nottingham, UK.
Paul P; Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
Regan F; Guy's and St Thomas's NHS Foundation Trust, London, UK.
Reilly P; Torbay and South Devon NHS Foundation Trust, Torquay, UK.
Sachdev P; Nottingham University Hospitals NHS Foundation Trust, Nottingham, UK.
Sakremath R; Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, UK.
Semple C; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Sharples K; Bart's Health NHS Trust, London, UK.
Skae M; Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Timmis A; Countess of Chester Hospital NHS Foundation Trust, Chester, UK.
Williams E; Hampshire Hospitals NHS Foundation Trust, Winchester, UK.
Wright N; Sheffield Children's Hospital NHS Foundation Trust, Sheffield, S102TH, UK.
Soni A; Sheffield Children's Hospital NHS Foundation Trust, Sheffield, S102TH, UK. .; Pokaż więcej
Źródło:: BMC medicine [BMC Med] 2024 Apr 02; Vol. 22 (1), pp. 144. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/diagnosis
Diabetes Mellitus, Type 2*/epidemiology
Diabetes Mellitus, Type 2*/therapy
Metformin*
Adult ; Humans ; Child ; Adolescent ; Comorbidity ; Obesity ; United Kingdom/epidemiology

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Skocz do pozycji: 9.

Tytuł:: Evaluation of OCT2-mediated drug-drug interactions between ulotaront and metformin in subjects with schizophrenia.
Autorzy:: Xiao G; Sumitomo Pharma America, Inc, Cambridge, Massachusetts, USA.
Tsukada H; Sumitomo Pharma America, Inc, Cambridge, Massachusetts, USA.
Chen YL; Sumitomo Pharma America, Inc, Cambridge, Massachusetts, USA.
Shi L; Sumitomo Pharma America, Inc, Cambridge, Massachusetts, USA.
Hopkins SC; Sumitomo Pharma America, Inc, Cambridge, Massachusetts, USA.
Galluppi GR; Sumitomo Pharma America, Inc, Cambridge, Massachusetts, USA.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Apr; Vol. 12 (2), pp. e1191.
Typ publikacji:: Randomized Controlled Trial; Journal Article
MeSH Terms:: Metformin*/therapeutic use
Metformin*/pharmacology
Pyrans*
Schizophrenia*/drug therapy
Adult ; Humans ; Chromatography, Liquid ; Cross-Over Studies ; Drug Interactions/genetics ; Single-Blind Method ; Tandem Mass Spectrometry ; Organic Cation Transporter 2/drug effects

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Skocz do pozycji: 10.

Tytuł:: Effect of metformin on anti-mullerian hormone levels in women with polycystic ovarian syndrome: a systematic review and meta-regression analysis of randomized controlled trials with.
Autorzy:: Mehdinezhad Roshan M; Student Research Committee, Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sohouli MH; Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Izze da Silva Magalhães E; Federal University of Rio Grande do Sul, Postgraduate Program in Food, Nutrition and Health, Porto Alegre, Rio Grande do Sul, Brazil.
Hekmatdoost A; Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. a_.; Pokaż więcej
Źródło:: BMC endocrine disorders [BMC Endocr Disord] 2024 Mar 29; Vol. 24 (1), pp. 43. Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:: Systematic Review; Meta-Analysis; Journal Article
MeSH Terms:: Polycystic Ovary Syndrome*/drug therapy
Metformin*/therapeutic use
Peptide Hormones*
Female ; Humans ; Anti-Mullerian Hormone ; Randomized Controlled Trials as Topic ; Regression Analysis

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Skocz do pozycji: 11.

Tytuł:: Evaluating synergistic effects of metformin and simvastatin on ovarian cancer cells.
Autorzy:: Mikhael S; Laboratory of Cancer and Metabolism, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Kurdi A; Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Khoueiry-Zgheib N; Department of Pharmacology and Toxicology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Tahtouh R; Laboratory of Cancer and Metabolism, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Nasr R; Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Hilal G; Laboratory of Cancer and Metabolism, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 15; Vol. 19 (3), pp. e0298127. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/pathology
Metformin*/pharmacology
Metformin*/therapeutic use
Humans ; Female ; Apoptosis ; Simvastatin/pharmacology ; Simvastatin/therapeutic use ; Cell Line, Tumor

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Skocz do pozycji: 12.

Tytuł:: Antidiabetic drug administration prevents bone mineral density loss: Evidence from a two-sample Mendelian randomization study.
Autorzy:: Chen M; School of Pharmacy, Quanzhou Medical College, Quanzhou, China.
Lin S; School of Pharmacy, Quanzhou Medical College, Quanzhou, China.
Chen W; School of Pharmacy, Quanzhou Medical College, Quanzhou, China.
Chen X; Department of Orthopaedic Surgery, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 07; Vol. 19 (3), pp. e0300009. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus*
Gliclazide*/pharmacology
Gliclazide*/therapeutic use
Metformin*/pharmacology
Metformin*/therapeutic use
Humans ; Bone Density/genetics ; Genome-Wide Association Study ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Insulin ; Insulin, Regular, Human ; Mendelian Randomization Analysis ; Polymorphism, Single Nucleotide ; Reproducibility of Results ; Rosiglitazone

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Skocz do pozycji: 13.

Tytuł:: Metformin in Esophageal Carcinoma: Exploring Molecular Mechanisms and Therapeutic Insights.
Autorzy:: Papadakos SP; First Department of Pathology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Goudi, 11527 Athens, Greece.
Argyrou A; Academic Department of Gastroenterology, Laikon General Hospital, Athens University Medical School, 11527 Athens, Greece.
Lekakis V; Academic Department of Gastroenterology, Laikon General Hospital, Athens University Medical School, 11527 Athens, Greece.
Arvanitakis K; First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.; Basic and Translational Research Unit (BTRU), Special Unit for Biomedical Research and Education (BRESU), Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Kalisperati P; Pathophysiology Department, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Stergiou IE; Pathophysiology Department, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Konstantinidis I; Department of Internal Medicine, University of Connecticut, Farmington, CT 06030, USA.
Schizas D; First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Koufakis T; Second Propaedeutic Department of Internal Medicine, General Hospital 'Hippokration', Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.
Germanidis G; First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.; Basic and Translational Research Unit (BTRU), Special Unit for Biomedical Research and Education (BRESU), Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Theocharis S; First Department of Pathology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Goudi, 11527 Athens, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Metformin*/pharmacology
Antineoplastic Agents*/pharmacology
Esophageal Neoplasms*/drug therapy
Humans ; AMP-Activated Protein Kinases/metabolism ; Signal Transduction

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Skocz do pozycji: 14.

Tytuł:: Metformin and Glucose Concentration as Limiting Factors in Retinal Pigment Epithelial Cell Viability and Proliferation.
Autorzy:: Villa-Fernández E; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.
García AV; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.
Fernández-Fernández A; Asturias Central University Hospital, 33011 Oviedo, Asturias, Spain.
García-Villarino M; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Department of Medicine, University of Oviedo, 33006 Oviedo, Asturias, Spain.
Ares-Blanco J; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Asturias Central University Hospital, 33011 Oviedo, Asturias, Spain.; Department of Medicine, University of Oviedo, 33006 Oviedo, Asturias, Spain.
Pujante P; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Asturias Central University Hospital, 33011 Oviedo, Asturias, Spain.
González-Vidal T; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Asturias Central University Hospital, 33011 Oviedo, Asturias, Spain.
Fraga MF; Nanomaterials and Nanotechnology Research Center (CINN-CSIC), Health Research Institute of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Institute of Oncology of Asturias (IUOPA), 33006 Oviedo, Asturias, Spain.; Department of Organisms and Systems Biology (B.O.S), University of Oviedo, 33006 Oviedo, Asturias, Spain.
Torre EM; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Asturias Central University Hospital, 33011 Oviedo, Asturias, Spain.; Department of Medicine, University of Oviedo, 33006 Oviedo, Asturias, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Delgado E; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Asturias Central University Hospital, 33011 Oviedo, Asturias, Spain.; Department of Medicine, University of Oviedo, 33006 Oviedo, Asturias, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Lambert C; Endocrinology, Nutrition, Diabetes and Obesity Group, Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.; Department of Educational Sciences, University of Oviedo, 33006 Oviedo, Asturias, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 24; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:: Journal Article
MeSH Terms:: Metformin*/pharmacology
Diabetes Mellitus, Type 2*/drug therapy
Humans ; Hypoglycemic Agents/pharmacology ; Glucose/metabolism ; Cell Proliferation ; Epithelial Cells/metabolism ; Retinal Pigments

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Skocz do pozycji: 15.

Tytuł:: TGF-β1 Signaling Impairs Metformin Action on Glycemic Control.
Autorzy:: Pan Q; Department of Nutrition, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843, USA.
Ai W; Department of Nutrition, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843, USA.
Guo S; Department of Nutrition, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 19; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:: Journal Article
MeSH Terms:: Metformin*/pharmacology
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Humans ; Mice ; Animals ; Transforming Growth Factor beta1/metabolism ; Glycemic Control ; Glucose/metabolism

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Skocz do pozycji: 16.

Tytuł:: Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells.
Autorzy:: Kamen Y; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK. .
Evans KA; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK.
Sitnikov S; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK.
Spitzer SO; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK.
de Faria O Jr; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK.
Yucel M; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK.
Káradóttir RT; Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, CB2 A0W, UK. .; Department of Physiology, BioMedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 19; Vol. 14 (1), pp. 4091. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:: Journal Article
MeSH Terms:: Oligodendrocyte Precursor Cells*/metabolism
Metformin*/pharmacology
Metformin*/metabolism
Clemastine ; Receptors, N-Methyl-D-Aspartate/metabolism ; Myelin Sheath/metabolism ; Oligodendroglia/metabolism ; Cell Differentiation/physiology

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Skocz do pozycji: 17.

Tytuł:: Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol.
Autorzy:: Dixon-Zegeye M; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
Shaw R; Oncology Clinical Trials Office, University of Oxford, Old Road Campus Research Building, Oxford, UK.
Collins L; Oncology Clinical Trials Office, University of Oxford, Old Road Campus Research Building, Oxford, UK.
Perez-Smith K; Trial Support Unit, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, UK.
Ooms A; Centre for Statistics in Medicine and Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Headington, Oxford, UK.
Qiao M; Centre for Statistics in Medicine and Oxford Clinical Trials Research Unit (OCTRU), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Headington, Oxford, UK.
Pantziarka P; George Pantziarka TP53 Trust, 7 Surbiton Cres, Kingston upon Thames, UK.
Izatt L; Guy's and St Thomas' NHS Foundation Trust, Great Maze Pond, London, UK.
Tischkowitz M; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
Harrison RE; Department of Clinical Genetics, Nottingham University Hospitals NHS Trust, Hucknall Rd, Nottingham, UK.
George A; Royal Marsden Hospital, Fulham Road, London, UK.
Woodward ER; Division of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
Lord S; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.
Hawkes L; Oxford Centre for Genomic Medicine, ACE building, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, UK.
Evans DG; Division of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
Franklin J; Institute of Medical Imaging and Visualisation, Bournemouth University, St Pauls Lane, Bournemouth, UK.
Hanson H; Peninsula Clinical Genetics Service, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.; Faculty of Health and Life Sciences, University of Exeter, Heavitree Road, Exeter, UK.
Blagden SP; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK. .; Oncology Clinical Trials Office, University of Oxford, Old Road Campus Research Building, Oxford, UK. .; Pokaż więcej
Źródło:: Trials [Trials] 2024 Feb 03; Vol. 25 (1), pp. 103. Date of Electronic Publication: 2024 Feb 03.
Typ publikacji:: Clinical Trial Protocol; Journal Article
MeSH Terms:: Li-Fraumeni Syndrome*/diagnostic imaging
Li-Fraumeni Syndrome*/genetics
Li-Fraumeni Syndrome*/prevention & control
Metformin*/adverse effects
Adult ; Humans ; Mice ; Animals ; Quality of Life ; Germ-Line Mutation ; Magnetic Resonance Imaging ; Genetic Predisposition to Disease ; Randomized Controlled Trials as Topic ; Clinical Trials, Phase II as Topic

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Skocz do pozycji: 18.

Tytuł:: The potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c in type 2 diabetes.
Autorzy:: Henson J; NIHR, Leicester Biomedical Research Centre, Leicester, UK.; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Davies MJ; NIHR, Leicester Biomedical Research Centre, Leicester, UK.; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Brady EM; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Edwardson CL; NIHR, Leicester Biomedical Research Centre, Leicester, UK.; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Hall AP; Hanning Sleep Laboratory, Leicester General Hospital, Leicester, UK.
Khunti K; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.; NIHR, Applied Health Research Collaboration - East Midlands (NIHR ARC-EM), Leicester Diabetes Centre, Leicester, UK.
Redman E; Leicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, UK.
Rowlands AV; NIHR, Leicester Biomedical Research Centre, Leicester, UK.; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.; Alliance for Research in Exercise, Nutrition and Activity (ARENA), UniSA Allied Health and Human Performance, University of South Australia, Adelaide, Australia, Adelaide, South Australia, Australia.
Sargeant J; NIHR, Leicester Biomedical Research Centre, Leicester, UK.; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.; Leicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, UK.
Yates T; NIHR, Leicester Biomedical Research Centre, Leicester, UK.; Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.; Pokaż więcej
Źródło:: Journal of diabetes [J Diabetes] 2024 Feb; Vol. 16 (2), pp. e13495. Date of Electronic Publication: 2023 Nov 14.
Typ publikacji:: Letter
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Metformin*/therapeutic use
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use
Humans ; Glycated Hemoglobin ; Hypoglycemic Agents/therapeutic use

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Skocz do pozycji: 19.

Tytuł:: Effects of quercetin on polycystic ovary syndrome in animal models: a systematic review and meta-analysis.
Autorzy:: Su P; The Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Chen C; The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Pang L; The Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Wu K; The Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Sun Y; Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, China. .; Pokaż więcej
Źródło:: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2024 Apr 18; Vol. 22 (1), pp. 46. Date of Electronic Publication: 2024 Apr 18.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:: Polycystic Ovary Syndrome*/drug therapy
Polycystic Ovary Syndrome*/genetics
Polycystic Ovary Syndrome*/metabolism
Metformin*/therapeutic use
Insulin Resistance*
Female ; Animals ; Humans ; Quercetin/pharmacology ; Quercetin/therapeutic use ; Blood Glucose ; Vascular Endothelial Growth Factor A ; Luteinizing Hormone ; Insulin ; Follicle Stimulating Hormone ; Testosterone ; Cholesterol ; Triglycerides

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Skocz do pozycji: 20.

Tytuł:: Pharmacological Interventions of Atypical Antipsychotics Induced Weight Gain in the Pediatric Population: A Systemic Review of Current Evidence.
Autorzy:: Al Jumaili W; Texas Tech University Health Science Center at Permian Basin, Midland, TX, USA. Wisam_.
Muzwagi A; Texas Tech University Health Science Center at Permian Basin, Midland, TX, USA.
Shah K; Griffin Memorial Hospital-Oklahoma State University, Tulsa, OK, USA.
Trivedi C; Texas Tech University Health Science Center at Permian Basin, Midland, TX, USA.
Durga P; Texas Tech University Health Science Center at Permian Basin, Midland, TX, USA.
Mansuri Z; Harvard Medical School, Boston Children's Hospital, Boston, MA, USA.
Jain S; Regional Chair of Psychiatry Department, Texas Tech University Health Science Center at Permian Basin, Midland, TX, USA.
Al Jumaili Y; Midland College, Midland, TX, USA.; Pokaż więcej
Źródło:: Child psychiatry and human development [Child Psychiatry Hum Dev] 2024 Apr; Vol. 55 (2), pp. 479-487. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:: Systematic Review; Journal Article
MeSH Terms:: Antipsychotic Agents*/adverse effects
Melatonin*
Metformin*/therapeutic use
Child ; Humans ; Adolescent ; Topiramate ; Betahistine ; Weight Gain ; Amantadine

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