Temat: "metyrapone" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Metyrapone Treatment Protects Low-Density Lipoprotein Receptor Knockout Mice against Hypercorticosteronemia Development without Changing Atherosclerosis Susceptibility.
Autorzy:: van der Sluis RJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.
van den Aardweg T; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.
Sijsenaar TJP; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.
Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.; Pharmacy Leiden, Leiden, The Netherlands.
Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.; Pharmacy Leiden, Leiden, The Netherlands.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Aug 23; Vol. 13 (9). Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Metyrapone*
Atherosclerosis*/metabolism
Mice ; Animals ; Humans ; Female ; Mice, Knockout ; Cholesterol/metabolism ; Glucocorticoids ; Lipoproteins, LDL ; Cholic Acid ; Mice, Inbred C57BL

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Skocz do pozycji: 2.

Tytuł:: Repurposed drugs in combinations exert additive anti-chikungunya virus activity: an in-vitro study.
Autorzy:: Davuluri KS; Dengue & Chikungunya Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Ghanghav R; Dengue & Chikungunya Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Ahire G; Dengue & Chikungunya Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Kakade M; Dengue & Chikungunya Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Cherian S; Bioinformatics and Data Management Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Alagarasu K; Dengue & Chikungunya Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India. .
Parashar D; Dengue & Chikungunya Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India. .; Pokaż więcej
Źródło:: Virology journal [Virol J] 2024 Jan 04; Vol. 21 (1), pp. 5. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: Chikungunya virus*
Chikungunya Fever*/drug therapy
Animals ; Chlorocebus aethiops ; Humans ; Vero Cells ; Emetine/pharmacology ; Emetine/therapeutic use ; Enalaprilat/pharmacology ; Enalaprilat/therapeutic use ; Metyrapone/pharmacology ; Metyrapone/therapeutic use ; Virus Replication ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Drug Combinations

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Skocz do pozycji: 3.

Tytuł:: Glucocorticoid regulation of diurnal spine plasticity in the murine ventromedial prefrontal cortex.
Autorzy:: Miller AM; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Daniels RM; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Sheng JA; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Wu TJ; Department of Gynecologic Surgery and Obstetrics, Uniformed Services University, Bethesda, Maryland, USA.
Handa RJ; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.; Pokaż więcej
Źródło:: Journal of neuroendocrinology [J Neuroendocrinol] 2022 Dec; Vol. 34 (12), pp. e13212. Date of Electronic Publication: 2022 Nov 25.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Extinction, Psychological*/physiology
Glucocorticoids*/metabolism
Animals ; Mice ; Circadian Rhythm/physiology ; Fear/physiology ; Hypothalamo-Hypophyseal System/metabolism ; Metyrapone/pharmacology ; Mice, Inbred C57BL ; Pituitary-Adrenal System/metabolism ; Prefrontal Cortex/metabolism

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Skocz do pozycji: 4.

Tytuł:: Cushing syndrome as a failed cardiac screen in a patient with McCune-Albright syndrome: a case report.
Autorzy:: Foster C; Division of Endocrinology, Department of Pediatrics, University of Alabama at Birmingham, 1601 4th Avenue South, Birmingham, AL, 35233, USA. .
Al Zubeidi H; Division of Endocrinology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.
Diaz-Thomas A; Division of Endocrinology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.; Pokaż więcej
Źródło:: Journal of medical case reports [J Med Case Rep] 2022 Sep 15; Vol. 16 (1), pp. 342. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Cushing Syndrome*/complications
Fibrous Dysplasia, Polyostotic*/complications
Fibrous Dysplasia, Polyostotic*/diagnosis
Fibrous Dysplasia, Polyostotic*/genetics
Heart Defects, Congenital*/complications
Dexamethasone/therapeutic use ; GTP-Binding Protein alpha Subunits ; Humans ; Hydrocortisone/therapeutic use ; Hypertrophy, Left Ventricular/complications ; Infant ; Infant, Newborn ; Male ; Metyrapone/therapeutic use

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Skocz do pozycji: 5.

Tytuł:: Ectopic ACTH-producing neuroendocrine tumor occurring with large recurrent metastatic pheochromocytoma: a case report.
Autorzy:: Saishouji F; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Maeda S; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Hamada H; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Kimura N; Department of Diagnostic Pathology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, 16-18 Kawahara, Hakodate, Hokkaido, 041-8512, Japan.
Tamanoi A; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Nishida S; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Sakaguchi M; Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Igata M; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Yokoo K; Department of Diagnostic Pathology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Kawakami F; Department of Diagnostic Pathology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Araki E; Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan.
Kondo T; Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-Ward, Kumamoto, 860-8556, Japan. .; Pokaż więcej
Źródło:: BMC endocrine disorders [BMC Endocr Disord] 2022 Jul 19; Vol. 22 (1), pp. 184. Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: ACTH Syndrome, Ectopic*/diagnosis
ACTH Syndrome, Ectopic*/etiology
Adrenal Gland Neoplasms*/metabolism
Hypokalemia*/complications
Neuroendocrine Tumors*/complications
Pheochromocytoma*/metabolism
Pheochromocytoma*/surgery
Adrenocorticotropic Hormone/metabolism ; Aged, 80 and over ; Catecholamines ; Humans ; Hydrocortisone ; Male ; Metyrapone/therapeutic use ; Neoplasm Recurrence, Local

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Skocz do pozycji: 6.

Tytuł:: Elevated blood pressure in high-fat diet-exposed low birthweight rat offspring is most likely caused by elevated glucocorticoid levels due to abnormal pituitary negative feedback.
Autorzy:: Nemoto T; Department of Bioregulatory Science (Physiology), Nippon Medical School, Tokyo, Japan.
Nakakura T; Department of Anatomy, Graduate School of Medicine, Teikyo University, Tokyo, Japan.
Kakinuma Y; Department of Bioregulatory Science (Physiology), Nippon Medical School, Tokyo, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Aug 27; Vol. 15 (8), pp. e0238223. Date of Electronic Publication: 2020 Aug 27 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Blood Pressure/*physiology
Feedback, Physiological/*physiology
Glucocorticoids/*blood
Pituitary Diseases/*blood
Pituitary Diseases/*physiopathology
Pituitary Gland/*physiology
Animals ; Birth Weight/drug effects ; Birth Weight/physiology ; Blood Pressure/drug effects ; Corticosterone/blood ; Diet, High-Fat/adverse effects ; Female ; Humans ; Hypertension/blood ; Hypertension/physiopathology ; Infant, Low Birth Weight/blood ; Infant, Low Birth Weight/physiology ; Infant, Newborn ; Male ; Metyrapone/therapeutic use ; Pituitary Diseases/drug therapy ; Pituitary Gland/drug effects ; Pregnancy ; Prenatal Exposure Delayed Effects/blood ; Prenatal Exposure Delayed Effects/physiopathology ; Rats ; Rats, Wistar

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Skocz do pozycji: 7.

Tytuł:: Unexpected effects of metyrapone on corticosteroid receptor interaction with the genome and subsequent gene transcription in the hippocampus of male rats.
Autorzy:: Kennedy CLM; Neuro-Epigenetics Research Group, Bristol Medical School, University of Bristol, Bristol, UK.
Carter SD; Neuro-Epigenetics Research Group, Bristol Medical School, University of Bristol, Bristol, UK.
Mifsud KR; Neuro-Epigenetics Research Group, Bristol Medical School, University of Bristol, Bristol, UK.
Reul JMHM; Neuro-Epigenetics Research Group, Bristol Medical School, University of Bristol, Bristol, UK.; Pokaż więcej
Źródło:: Journal of neuroendocrinology [J Neuroendocrinol] 2020 Feb; Vol. 32 (2), pp. e12820. Date of Electronic Publication: 2019 Dec 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Enzyme Inhibitors/*administration & dosage
Genome/*drug effects
Hippocampus/*drug effects
Hippocampus/*metabolism
Metyrapone/*administration & dosage
Receptors, Glucocorticoid/*metabolism
Receptors, Mineralocorticoid/*metabolism
Transcription, Genetic/*drug effects
Animals ; Corticosterone/blood ; Immediate-Early Proteins/metabolism ; Male ; Period Circadian Proteins/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Rats, Wistar ; Stress, Psychological/metabolism ; Tacrolimus Binding Proteins/metabolism

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Skocz do pozycji: 8.

Tytuł:: ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review.
Autorzy:: Okumura T; Second Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.; Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Takayama S; Fourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Nishio SI; Fourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Miyakoshi T; Fourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Noguchi T; Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Kobayashi T; Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Fukushima T; Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Sekiguchi N; Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Otsuki T; Department of Central Laboratory, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Komatsu M; Fourth Department of Internal Medicine, Shinshu University School of Medicine, Asahi Matsumoto, Japan.
Koizumi T; Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Asahi Matsumoto, Japan.; Pokaż więcej
Źródło:: Thoracic cancer [Thorac Cancer] 2019 Jul; Vol. 10 (7), pp. 1648-1653. Date of Electronic Publication: 2019 Jun 11.
Typ publikacji:: Case Reports; Journal Article; Review
MeSH Terms:: Adrenocorticotropic Hormone/*blood
Neuroendocrine Tumors/*diagnosis
Psychotic Disorders/*etiology
Thymus Neoplasms/*diagnosis
Adult ; Female ; Humans ; Metyrapone/therapeutic use ; Multiple Pulmonary Nodules/diagnostic imaging ; Neuroendocrine Tumors/blood ; Potassium/therapeutic use ; Psychotic Disorders/blood ; Psychotic Disorders/drug therapy ; Thymus Neoplasms/blood ; Tomography, X-Ray Computed

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Skocz do pozycji: 9.

Tytuł:: Pathway analysis reveals common pro-survival mechanisms of metyrapone and carbenoxolone after traumatic brain injury.
Autorzy:: Hellmich HL; Department of Anesthesiology, University of Texas Medical Branch, Galveston, Texas, United States of America. />Rojo DR
Micci MA
Sell SL
Boone DR
Crookshanks JM
DeWitt DS
Masel BE
Prough DS; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013; Vol. 8 (1), pp. e53230. Date of Electronic Publication: 2013 Jan 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain Injuries/*drug therapy
Brain Injuries/*genetics
Carbenoxolone/*therapeutic use
Metyrapone/*therapeutic use
Signal Transduction/*genetics
Animals ; Brain Injuries/complications ; Brain Injuries/pathology ; Carbenoxolone/pharmacology ; Cell Death/drug effects ; Cell Death/genetics ; Cell Survival/drug effects ; Cell Survival/genetics ; Gene Expression Regulation/drug effects ; Hippocampus/drug effects ; Hippocampus/pathology ; Humans ; Male ; Metyrapone/pharmacology ; Nerve Degeneration/complications ; Nerve Degeneration/drug therapy ; Nerve Degeneration/pathology ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Stress, Physiological/drug effects ; Stress, Physiological/genetics

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Skocz do pozycji: 10.

Tytuł:: Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats.
Autorzy:: Goeders NE; Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA. />Cohen A
Fox BS
Azar MR
George O
Koob GF; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2012 Sep; Vol. 223 (1), pp. 17-25. Date of Electronic Publication: 2012 Mar 15.
Typ publikacji:: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Metyrapone/*pharmacology
Nicotine/*administration & dosage
Oxazepam/*pharmacology
Smoking Cessation/*methods
Animals ; Benzazepines/pharmacology ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Enzyme Inhibitors/administration & dosage ; Enzyme Inhibitors/pharmacology ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/pharmacology ; Infusions, Intravenous ; Male ; Metyrapone/administration & dosage ; Oxazepam/administration & dosage ; Quinoxalines/pharmacology ; Rats ; Rats, Wistar ; Reinforcement Schedule ; Self Administration ; Varenicline

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Skocz do pozycji: 11.

Tytuł:: Physiological and drug-induced changes in blood levels of adrenal steroids and their precursors in cynomolgus monkeys: An application of steroid profiling by LC-MS/MS for evaluation of the adrenal toxicity.
Autorzy:: Tochitani T; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Yamashita A; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Matsumoto I; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Kouchi M; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Fujii Y; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Yamada T; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
Miyawaki I; Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2019; Vol. 44 (9), pp. 575-584.
Typ publikacji:: Journal Article
MeSH Terms:: Adrenal Glands/*drug effects
Adrenal Glands/*metabolism
Aldosterone/*blood
Aldosterone/*metabolism
Androgens/*blood
Androgens/*metabolism
Chromatography, Liquid/*methods
Hydrocortisone/*blood
Hydrocortisone/*metabolism
Ketoconazole/*toxicity
Metyrapone/*toxicity
Tandem Mass Spectrometry/*methods
Animals ; Circadian Rhythm ; Desoxycorticosterone/metabolism ; Female ; Humans ; Macaca fascicularis ; Male ; Steroid 11-beta-Hydroxylase/antagonists & inhibitors

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Skocz do pozycji: 12.

Tytuł:: CYP11B1 has no role in mitotane action and metabolism in adrenocortical carcinoma cells.
Autorzy:: Germano A; Internal Medicine, Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.
Saba L; Internal Medicine, Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.
De Francia S; Internal Medicine, Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.
Rapa I; Pathology, Department of Oncology at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.
Perotti P; Internal Medicine, Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.
Berruti A; Oncology Unit, Department of Surgery, Radiology and Public Health, University of Brescia, ASST Spedali Civili di Brescia, Brescia, Italy.
Volante M; Pathology, Department of Oncology at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.
Terzolo M; Internal Medicine, Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2018 May 07; Vol. 13 (5), pp. e0196931. Date of Electronic Publication: 2018 May 07 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adrenocortical Carcinoma/*drug therapy
Cell Proliferation/*drug effects
Mitotane/*pharmacology
Steroid 11-beta-Hydroxylase/*genetics
Adrenocortical Carcinoma/metabolism ; Adrenocortical Carcinoma/pathology ; Antineoplastic Agents, Hormonal/pharmacology ; Cell Line, Tumor ; Humans ; Metyrapone/pharmacology ; Steroid 11-beta-Hydroxylase/antagonists & inhibitors ; Steroid 11-beta-Hydroxylase/metabolism

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Skocz do pozycji: 13.

Tytuł:: Metyrapone and mifepristone reverse recognition memory loss induced by spontaneous morphine withdrawal in mice.
Autorzy:: Mesripour A; Isfahan Pharmaceutical Sciences Research Centre, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran. />Hajhashemi V
Rabbani M; Pokaż więcej
Źródło:: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2008 Apr; Vol. 102 (4), pp. 377-81.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Enzyme Inhibitors/*pharmacology
Hormone Antagonists/*pharmacology
Memory/*drug effects
Memory Disorders/*drug therapy
Metyrapone/*pharmacology
Mifepristone/*pharmacology
Morphine/*adverse effects
Substance Withdrawal Syndrome/*drug therapy
Animals ; Disease Models, Animal ; Enzyme Inhibitors/administration & dosage ; Glucocorticoids/blood ; Glucocorticoids/metabolism ; Hormone Antagonists/administration & dosage ; Injections, Subcutaneous ; Male ; Memory Disorders/chemically induced ; Memory Disorders/metabolism ; Metyrapone/administration & dosage ; Mice ; Mifepristone/administration & dosage ; Receptors, Glucocorticoid/antagonists & inhibitors ; Receptors, Glucocorticoid/metabolism ; Recognition, Psychology/drug effects ; Steroid 11-beta-Hydroxylase/antagonists & inhibitors ; Steroid 11-beta-Hydroxylase/metabolism ; Substance Withdrawal Syndrome/metabolism ; Substance Withdrawal Syndrome/psychology ; Time Factors

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Skocz do pozycji: 14.

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Szczegóły

Skocz do pozycji: 15.

Tytuł:: Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review.
Autorzy:: Iwayama H; Department of Paediatrics, Aichi Medical University, School of Medicine, Nagakute, Japan. .
Hirase S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Aichi Medical University, School of Medicine, Nagakute, Japan.
Nomura Y; Division of Endocrinology and Metabolism, Department of Internal Medicine, Aichi Medical University, School of Medicine, Nagakute, Japan.
Ito T; Division of Endocrinology and Metabolism, Department of Internal Medicine, Aichi Medical University, School of Medicine, Nagakute, Japan.
Morita H; Division of Endocrinology and Metabolism, Department of Internal Medicine, Aichi Medical University, School of Medicine, Nagakute, Japan.
Otake K; Division of Endocrinology and Metabolism, Department of Internal Medicine, Aichi Medical University, School of Medicine, Nagakute, Japan.
Okumura A; Department of Paediatrics, Aichi Medical University, School of Medicine, Nagakute, Japan.
Takagi J; Division of Endocrinology and Metabolism, Department of Internal Medicine, Aichi Medical University, School of Medicine, Nagakute, Japan.; Pokaż więcej
Źródło:: BMC endocrine disorders [BMC Endocr Disord] 2018 Mar 27; Vol. 18 (1), pp. 19. Date of Electronic Publication: 2018 Mar 27.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: ACTH Syndrome, Ectopic/*complications
Adrenocorticotropic Hormone/*blood
Hydrocortisone/*blood
Lung Neoplasms/*drug therapy
Metyrapone/*therapeutic use
Aged ; Female ; Humans ; Lung Neoplasms/blood ; Lung Neoplasms/etiology ; Prognosis ; Remission Induction

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Skocz do pozycji: 16.

Tytuł:: Effects of the cortisol synthesis inhibitor metyrapone on the response to carbon dioxide challenge in panic disorder.
Autorzy:: Belgorodsky A; Division of Psychiatry, Ben Gurion University of the Negev, Beer-sheba, Israel.
Knyazhansky L
Loewenthal U
Arbelle J
Cohen H
Benjamin J; Pokaż więcej
Źródło:: Depression and anxiety [Depress Anxiety] 2005; Vol. 21 (3), pp. 143-8.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carbon Dioxide*/administration & dosage
Antimetabolites/*pharmacology
Hydrocortisone/*metabolism
Metyrapone/*pharmacology
Panic Disorder/*diagnosis
Administration, Inhalation ; Adrenocorticotropic Hormone/blood ; Antimetabolites/administration & dosage ; Corticotropin-Releasing Hormone/physiology ; Diagnostic and Statistical Manual of Mental Disorders ; Humans ; Hydrocortisone/biosynthesis ; Hydrocortisone/blood ; Hypothalamo-Hypophyseal System/drug effects ; Metyrapone/administration & dosage ; Panic Disorder/physiopathology ; Pituitary-Adrenal System/drug effects ; Surveys and Questionnaires

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Skocz do pozycji: 17.

Tytuł:: A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone.
Autorzy:: Zieleniewski W; a NZOZ Salve, Unit of Endocrinology , Lodz , Poland and.
Michalak R; b Department of Clinical Endocrinology and Metabolic Disease , Polish Mother's Memorial Hospital Research Institute , Lodz , Poland.; Pokaż więcej
Źródło:: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2017 May; Vol. 33 (5), pp. 349-352. Date of Electronic Publication: 2017 Feb 26.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Cushing Syndrome/*drug therapy
Cushing Syndrome/*pathology
Ketoconazole/*administration & dosage
Metyrapone/*administration & dosage
Pregnancy Complications/*drug therapy
Pregnancy Complications/*pathology
Adult ; Drug Therapy, Combination ; Female ; Humans ; Pregnancy ; Treatment Outcome
SCR Disease Name:: Acth-Independent Macronodular Adrenal Hyperplasia