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Tytuł :
Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.
Autorzy :
Gu B; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, USA.; Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA.
Shorter JR; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services, Copenhagen, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Williams LH; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Bell TA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Hock P; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Dalton KA; Neuroscience Curriculum, University of North Carolina, Chapel Hill, NC, USA.
Pan Y; Neuroscience Curriculum, University of North Carolina, Chapel Hill, NC, USA.
Miller DR; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Shaw GD; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Philpot BD; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, USA.; Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.; Neuroscience Curriculum, University of North Carolina, Chapel Hill, NC, USA.
Pardo-Manuel de Villena F; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
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Źródło :
Epilepsia [Epilepsia] 2020 Sep; Vol. 61 (9), pp. 2010-2021. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice*
Collaborative Cross Mice/*genetics
Epilepsy/*genetics
Hippocampus/*metabolism
Seizures/*genetics
Animals ; Chromosome Mapping ; Convulsants ; Epilepsy/chemically induced ; Epilepsy/metabolism ; Epilepsy/physiopathology ; Excitatory Amino Acid Agonists ; Flurothyl ; Gene Expression ; Gene Expression Profiling ; Genetic Predisposition to Disease ; Genotype ; Kainic Acid ; Mice, Inbred Strains ; Pentylenetetrazole ; Phenotype ; Quantitative Trait Loci ; Seizures/chemically induced ; Seizures/metabolism ; Seizures/physiopathology ; Sudden Unexpected Death in Epilepsy ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Comparative Effects of 1/4-inch and 1/8-inch Corncob Bedding on Cage Ammonia Levels, Behavior, and Respiratory Pathology of Male C57BL/6 and 129S1/Svlm Mice.
Autorzy :
Cantara SI; Division of Animal Resources, Emory University, Atlanta, Georgia;, Email: .
Blas-Machado U; Athens Veterinary Diagnostic Laboratory and Department of Veterinary Pathology, University of Georgia, College of Veterinary Medicine, Athens, Georgia.
Zhao X; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Moore RH; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Schroeder JP; Emory Integrated Core Facilities, Rodent Behavioral Core, Emory University School of Medicine, Atlanta, Georgia.
Lee VK; Division of Animal Resources, Emory University, Atlanta, Georgia; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
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Źródło :
Journal of the American Association for Laboratory Animal Science : JAALAS [J Am Assoc Lab Anim Sci] 2020 Nov 01; Vol. 59 (6), pp. 695-702. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Housing, Animal*
Mice, 129 Strain*
Mice, Inbred C57BL*
Ammonia/*toxicity
Behavior, Animal/*drug effects
Animals ; Male ; Maze Learning ; Mice ; Nose/pathology ; Species Specificity ; Zea mays
Czasopismo naukowe
Tytuł :
Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice.
Autorzy :
Hasan KM; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Friedman TC; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Parveen M; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Espinoza-Derout J; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Bautista F; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Razipour MM; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Shao XM; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Jordan MC; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Roos KP; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Mahata SK; VA San Diego Health Care System and University of California, San Diego, CA, United States of America.
Sinha-Hikim AP; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Oct 01; Vol. 15 (10), pp. e0239671. Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Electronic Nicotine Delivery Systems*
Mice, Obese*
Diet, High-Fat/*adverse effects
Heart/*drug effects
Myocardium/*pathology
Smoking/*adverse effects
Animals ; Cotinine/blood ; Echocardiography ; Fatty Acids, Nonesterified/blood ; Heart/physiopathology ; Heart Ventricles/drug effects ; Heart Ventricles/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Electron, Transmission ; Myocardium/ultrastructure ; Nicotine/adverse effects ; Nicotine/blood ; Oxidative Stress/drug effects ; Ventricular Dysfunction, Left/chemically induced
Czasopismo naukowe
Tytuł :
Oral exposure to BDE-209 modulates metastatic spread of melanoma in C57BL/6 mice inoculated with B16-F10 cells.
Autorzy :
Brito PM; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
Biscaia SMP; Laboratório de Investigações de Polissacarídeos Sulfatados, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
de Souza TL; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
Ramos AB; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
Leão-Buchir J; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
de Almeida Roque A; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
de Lima Bellan D; Laboratório de Investigações de Polissacarídeos Sulfatados, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
da Silva Trindade E; Laboratório de Investigações de Polissacarídeos Sulfatados, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
Filipak Neto F; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil.
de Oliveira Ribeiro CA; Laboratório de Toxicologia Celular, Departamento de Biologia Celular, Universidade Federal Do Paraná, CEP 81.531-980, Curitiba, Brazil. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Dec; Vol. 260, pp. 127556. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Mice, Inbred C57BL*
Halogenated Diphenyl Ethers/*pharmacology
Melanoma/*pathology
Neoplasm Metastasis/*pathology
Alanine Transaminase/blood ; Animals ; Aspartate Aminotransferases/blood ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Flame Retardants/pharmacology ; Halogenated Diphenyl Ethers/toxicity ; Heterografts ; Humans ; Liver/drug effects ; Liver/pathology ; Melanoma, Experimental ; Mice
Czasopismo naukowe
Tytuł :
Immune characterization of pre-clinical murine models of neuroblastoma.
Autorzy :
Webb ER; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.; Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
Lanati S; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Wareham C; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Easton A; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.; Cellular Pathology, University Hospitals Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.; Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, UK.
Dunn SN; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Inzhelevskaya T; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Sadler FM; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
James S; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Ashton-Key M; Cellular Pathology, University Hospitals Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.
Cragg MS; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Beers SA; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Gray JC; Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton Faculty of Medicine, Southampton General Hospital (MP127), Tremona Road, Southampton, Hampshire, SO16 6YD, UK. .
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 07; Vol. 10 (1), pp. 16695. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mice, Transgenic*
Antineoplastic Agents/*therapeutic use
Cyclophosphamide/*therapeutic use
Neuroblastoma/*immunology
Animals ; Cell Line, Tumor ; Disease Models, Animal ; Immunotherapy ; Mice ; Neuroblastoma/drug therapy ; Neuroblastoma/pathology ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.
Autorzy :
Gu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Chen Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Yang G; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
He L; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Fan H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang Y; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
Teng Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhao Z; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Cui Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Li Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Li XF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Li J; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhang NN; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Yang X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Chen S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Guo Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhao G; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Luo DY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Yang X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
Li Y; Institute of Military Cognition and Brain Sciences, Beijing 100850, China.
Han G; Institute of Military Cognition and Brain Sciences, Beijing 100850, China.
He Y; Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Zhou X; Laboratory Animal Center, Academy of Military Medical Sciences, Beijing 100071, China.
Geng S; Beijing JOINN Biologics Co., Beijing 100176, China.
Sheng X; Beijing JOINN Biologics Co., Beijing 100176, China.
Jiang S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China. .
Sun S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China. .
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China. .
Zhou Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Sep 25; Vol. 369 (6511), pp. 1603-1607. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice*
Betacoronavirus/*immunology
Coronavirus Infections/*prevention & control
Pandemics/*prevention & control
Pneumonia, Viral/*prevention & control
Viral Vaccines/*immunology
Administration, Intranasal ; Angiotensin-Converting Enzyme 2 ; Animals ; Betacoronavirus/genetics ; Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Vaccines ; Coronavirus Infections/immunology ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Immunogenicity, Vaccine ; Lung/virology ; Lung Diseases, Interstitial/virology ; Mice, Inbred BALB C ; Mice, Transgenic ; Mutation ; Peptidyl-Dipeptidase A/genetics ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/immunology ; Viral Vaccines/administration & dosage ; Virulence/genetics
Czasopismo naukowe
Tytuł :
Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Autorzy :
Koneval Z; Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.
Knox KM; Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.
Memon A; Neuroscience Undergraduate Program, University of Washington, Seattle, Washington, USA.
Zierath DK; Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.
White HS; Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.
Barker-Haliski M; Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.
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Źródło :
Epilepsia [Epilepsia] 2020 Sep; Vol. 61 (9), pp. 2022-2034. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Outbred Strains*
Disease Models, Animal*
Mice, Inbred C57BL*
Anticonvulsants/*pharmacology
Drug Resistant Epilepsy/*physiopathology
Locomotion/*drug effects
Seizures/*physiopathology
Animals ; Anticonvulsants/therapeutic use ; Behavior, Animal/drug effects ; Brain/drug effects ; Carbamazepine/pharmacology ; Carbamazepine/therapeutic use ; Cornea ; Diazepam/pharmacology ; Diazepam/therapeutic use ; Dose-Response Relationship, Drug ; Drug Discovery ; Drug Evaluation, Preclinical ; Drug Resistant Epilepsy/drug therapy ; Electroshock ; Kindling, Neurologic ; Lamotrigine/pharmacology ; Lamotrigine/therapeutic use ; Levetiracetam/pharmacology ; Levetiracetam/therapeutic use ; Mice ; Mice, Inbred Strains ; Open Field Test ; Phenobarbital/pharmacology ; Phenobarbital/therapeutic use ; Seizures/drug therapy ; Treatment Outcome ; Valproic Acid/pharmacology ; Valproic Acid/therapeutic use
Czasopismo naukowe
Tytuł :
The D2.mdx mouse as a preclinical model of the skeletal muscle pathology associated with Duchenne muscular dystrophy.
Autorzy :
Hammers DW; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, 1200 Newell Dr., ARB R5-216, Gainesville, FL, 32610-0267, USA.; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA.
Hart CC; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, 1200 Newell Dr., ARB R5-216, Gainesville, FL, 32610-0267, USA.; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA.
Matheny MK; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, 1200 Newell Dr., ARB R5-216, Gainesville, FL, 32610-0267, USA.; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA.
Wright LA; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, 1200 Newell Dr., ARB R5-216, Gainesville, FL, 32610-0267, USA.; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA.
Armellini M; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, 1200 Newell Dr., ARB R5-216, Gainesville, FL, 32610-0267, USA.; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA.
Barton ER; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Sweeney HL; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, 1200 Newell Dr., ARB R5-216, Gainesville, FL, 32610-0267, USA. .; Myology Institute, University of Florida College of Medicine, Gainesville, FL, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 21; Vol. 10 (1), pp. 14070. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mice, Inbred mdx*
Muscle, Skeletal/*pathology
Muscular Dystrophy, Animal/*pathology
Muscular Dystrophy, Duchenne/*pathology
Animals ; Cytokines/metabolism ; Disease Models, Animal ; Disease Progression ; Inflammation ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred DBA ; Muscle, Skeletal/metabolism ; Muscular Dystrophy, Animal/genetics ; Random Allocation ; Specimen Handling ; Transcriptome
Czasopismo naukowe
Tytuł :
The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models.
Autorzy :
Ramelow J; Department of Human & Molecular Genetics, Herbert Wertheim College of Medicine, The Florida International University, Miami, Florida, 33199, USA.; Biomolecular Sciences Institute, The Florida International University, Miami, Florida, 33199, USA.; Biological Sciences, College of Arts, Science and Education, The Florida International University, Miami, Florida, 33199, USA.
Brooks CD; Comprehensive Cancer Center at the Ohio State University College of Medicine, Columbus, OH, 43210, USA.
Gao L; Department of Human & Molecular Genetics, Herbert Wertheim College of Medicine, The Florida International University, Miami, Florida, 33199, USA.
Almiman AA; Department of Human & Molecular Genetics, Herbert Wertheim College of Medicine, The Florida International University, Miami, Florida, 33199, USA.
Williams TM; Comprehensive Cancer Center at the Ohio State University College of Medicine, Columbus, OH, 43210, USA.
Villalona-Calero MA; Biomolecular Sciences Institute, The Florida International University, Miami, Florida, 33199, USA. .
Duan W; Department of Human & Molecular Genetics, Herbert Wertheim College of Medicine, The Florida International University, Miami, Florida, 33199, USA. .; Biomolecular Sciences Institute, The Florida International University, Miami, Florida, 33199, USA. .; Comprehensive Cancer Center at the Ohio State University College of Medicine, Columbus, OH, 43210, USA. .
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Źródło :
BMC cancer [BMC Cancer] 2020 Aug 08; Vol. 20 (1), pp. 738. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Genes, p53*
Mice, Transgenic*
Mutation*
Lung Neoplasms/*genetics
Age Factors ; Animals ; Crosses, Genetic ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred A ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2.
Autorzy :
Jiang RD; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Liu MQ; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Chen Y; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Shan C; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Zhou YW; Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Shen XR; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Li Q; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Zhang L; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Zhu Y; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Si HR; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Wang Q; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Min J; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Wang X; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Zhang W; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Li B; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Zhang HJ; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Baric RS; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Zhou P; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China.
Yang XL; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China. Electronic address: .
Shi ZL; CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People's Republic of China. Electronic address: .
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Źródło :
Cell [Cell] 2020 Jul 09; Vol. 182 (1), pp. 50-58.e8. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*/genetics
Betacoronavirus/*physiology
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Angiotensin-Converting Enzyme 2 ; Animals ; COVID-19 ; Female ; Humans ; Lung Diseases, Interstitial/pathology ; Lung Diseases, Interstitial/virology ; Male ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Pandemics ; Peptidyl-Dipeptidase A/genetics ; SARS-CoV-2 ; Viral Tropism ; Weight Loss
Czasopismo naukowe
Tytuł :
High-pH reversed-phase fractionated neural retina proteome of normal growing C57BL/6 mouse.
Autorzy :
Sze YH; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, Hong Kong Polytechnic University, Hong Kong, China.
Zhao Q; State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hong Kong, China.; Centre for Eye and Vision Research, Hong Kong, China.
Cheung JKW; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, Hong Kong Polytechnic University, Hong Kong, China.
Li KK; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, Hong Kong Polytechnic University, Hong Kong, China.
Tse DYY; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, Hong Kong Polytechnic University, Hong Kong, China.; Centre for Eye and Vision Research, Hong Kong, China.
To CH; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, Hong Kong Polytechnic University, Hong Kong, China.; Centre for Eye and Vision Research, Hong Kong, China.
Lam TC; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, Hong Kong Polytechnic University, Hong Kong, China. .; Centre for Eye and Vision Research, Hong Kong, China. .
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Źródło :
Scientific data [Sci Data] 2021 Jan 26; Vol. 8 (1), pp. 27. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Dataset; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteome*
Retina*/physiology
Mice, Inbred C57BL/*genetics
Animals ; Hydrogen-Ion Concentration ; Mice ; Mice, Inbred C57BL/physiology ; Proteomics
Czasopismo naukowe
Tytuł :
Fresh frozen plasma attenuates lung injury in a novel model of prolonged hypotensive resuscitation.
Autorzy :
Chipman AM; From the Shock Trauma Center (A.M.C., F.W., R.A.K.), University of Maryland School of Medicine, Baltimore, Maryland; Department of Laboratory Medicine (S.P.), University of California San Francisco, California; and United States Naval Medical Research Unit-San Antonio (A.J.B., J.J.G.), Fort Sam Houston, Houston, Texas.
Wu F
Pati S
Burdette AJ
Glaser JJ
Kozar RA
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Źródło :
The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2020 Aug; Vol. 89 (2S Suppl 2), pp. S118-S125.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Models, Animal*
Mice, Inbred C57BL*
Plasma*
Lung Injury/*therapy
Resuscitation/*methods
Shock, Hemorrhagic/*therapy
Animals ; Chemokines/blood ; Cytokines/blood ; Hypotension ; Lung/pathology ; Lung Injury/pathology ; Male ; Mice ; Pneumonia/pathology ; War-Related Injuries/therapy
Czasopismo naukowe
Tytuł :
[Generation and validation of inducible osteoblast-specific Stat3 knockout mice].
Autorzy :
Gong XY; Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011, China. E-mail:.
Huang XR
Zhou SR
Yang YL
Xu HY
Jin AT
Dai QG
Jiang LY
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Źródło :
Shanghai kou qiang yi xue = Shanghai journal of stomatology [Shanghai Kou Qiang Yi Xue] 2020 Aug; Vol. 29 (4), pp. 337-342.
Typ publikacji :
Journal Article
MeSH Terms :
Mice, Knockout*
Osteoblasts*
STAT3 Transcription Factor*
Tooth Movement Techniques*
Animals ; Gene Knockout Techniques ; Mice ; RNA, Messenger
Czasopismo naukowe
Tytuł :
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Autorzy :
Israelow B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.; Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT.
Song E; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
Mao T; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
Lu P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
Meir A; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT.
Liu F; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
Alfajaro MM; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT.
Wei J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT.
Dong H; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
Homer RJ; Department of Pathology, Yale University School of Medicine, New Haven, CT.
Ring A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.
Wilen CB; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT.
Iwasaki A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT.; Howard Hughes Medical Institute, Chevy Chase, MD.
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Źródło :
The Journal of experimental medicine [J Exp Med] 2020 Dec 07; Vol. 217 (12).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Disease Models, Animal*
Betacoronavirus/*metabolism
Coronavirus Infections/*metabolism
Interferon Type I/*metabolism
Mice/*genetics
Peptidyl-Dipeptidase A/*metabolism
Pneumonia, Viral/*metabolism
Angiotensin-Converting Enzyme 2 ; Animals ; COVID-19 ; Cell Line, Tumor ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Dependovirus/genetics ; Female ; Humans ; Inflammation/metabolism ; Lung/pathology ; Lung/virology ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Pandemics ; Parvoviridae Infections/metabolism ; Parvoviridae Infections/virology ; Peptidyl-Dipeptidase A/genetics ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Signal Transduction/genetics ; Virus Replication/genetics
Czasopismo naukowe
Tytuł :
Impact of virus-antibody interactions on viral clearance in anion exchange chromatography.
Autorzy :
Hung J; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA.
Lam SF; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA.
Tan Z; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA. Electronic address: .
Choy D; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA.
Chennamsetty N; Biologics Analytical Development and Attribute Science, Bristol-Myers Squibb, New Brunswick, NJ, USA.
Lewandowski A; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA.
Qi W; Thermo Fisher Scientific, Waltham, MA, USA.
Lynch M; Thermo Fisher Scientific, Waltham, MA, USA.
Ghose S; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA.
Li ZJ; Biologics Process Development, Bristol-Myers Squibb, Devens, MA, USA.
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2020 Dec 06; Vol. 1633, pp. 461635. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal/*metabolism
Chromatography, Ion Exchange/*standards
Minute Virus of Mice/*metabolism
Viruses/*metabolism
Animals ; Anions/chemistry ; Antibodies, Monoclonal/chemistry ; Mice ; Viruses/chemistry
Czasopismo naukowe
Tytuł :
Binding of CCCTC-Binding Factor (CTCF) to the Minute Virus of Mice Genome Is Important for Proper Processing of Viral P4-Generated Pre-mRNAs.
Autorzy :
Boftsi M; Pathobiology Area Graduate Program, Christopher S. Bond Life Sciences Center, School of Medicine, University of Missouri-Columbia, Columbia, MO 65211, USA.
Majumder K; Christopher S. Bond Life Sciences Center, Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri-Columbia, Columbia, MO 65211, USA.
Burger LR; Christopher S. Bond Life Sciences Center, Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri-Columbia, Columbia, MO 65211, USA.
Pintel DJ; Christopher S. Bond Life Sciences Center, Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri-Columbia, Columbia, MO 65211, USA.
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Źródło :
Viruses [Viruses] 2020 Nov 30; Vol. 12 (12). Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genome, Viral*
Host-Pathogen Interactions*
CCCTC-Binding Factor/*metabolism
Minute Virus of Mice/*physiology
Parvoviridae Infections/*veterinary
Rodent Diseases/*metabolism
Rodent Diseases/*virology
Animals ; DNA-Binding Proteins/metabolism ; Fluorescent Antibody Technique ; Gene Expression Regulation, Viral ; Humans ; Introns ; Mice ; Models, Biological ; Mutation ; Nucleoproteins/metabolism ; Protein Binding ; RNA Precursors ; RNA, Messenger ; RNA, Viral ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
The NS1 protein of the parvovirus MVM Aids in the localization of the viral genome to cellular sites of DNA damage.
Autorzy :
Majumder K; Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri, United States of America.; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, United States of America.
Boftsi M; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, United States of America.; Pathobiology Area Graduate Program, University of Missouri, Columbia, Missouri, United States of America.
Whittle FB; Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri, United States of America.; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, United States of America.
Wang J; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, United States of America.; Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, Missouri, United States of America.
Fuller MS; Ultragenyx Gene Therapy, Cambridge, Massachusetts, United States of America.
Joshi T; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, United States of America.; Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, Missouri, United States of America.; Department of Health Management and Informatics, University of Missouri School of Medicine, Columbia, Missouri, United States of America.; MU Institute of Data Science and Informatics, University of Missouri, Columbia, Missouri, United States of America.
Pintel DJ; Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri, United States of America.; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Oct 16; Vol. 16 (10), pp. e1009002. Date of Electronic Publication: 2020 Oct 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Damage*
Minute Virus of Mice/*genetics
Minute Virus of Mice/*metabolism
Viral Nonstructural Proteins/*metabolism
Animals ; Cell Line ; DNA Replication ; DNA, Viral/genetics ; DNA-Binding Proteins/genetics ; Female ; Genome, Viral ; Humans ; Male ; Mice ; Parvoviridae Infections/genetics ; Parvoviridae Infections/virology ; Parvovirus/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
Autorzy :
Zhan L; Gladstone Institute of Neurological Diseases, San Francisco, United States.
Fan L; Helen and Robert Appel Alzheimer's Disease Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.
Kodama L; Gladstone Institute of Neurological Diseases, San Francisco, United States.; Helen and Robert Appel Alzheimer's Disease Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, United States.; Medical Scientist Training Program, University of California at San Francisco, San Francisco, United States.
Sohn PD; Gladstone Institute of Neurological Diseases, San Francisco, United States.
Wong MY; Helen and Robert Appel Alzheimer's Disease Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.
Mousa GA; Helen and Robert Appel Alzheimer's Disease Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.
Zhou Y; Gladstone Institute of Neurological Diseases, San Francisco, United States.
Li Y; Gladstone Institute of Neurological Diseases, San Francisco, United States.
Gan L; Gladstone Institute of Neurological Diseases, San Francisco, United States.; Helen and Robert Appel Alzheimer's Disease Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, United States.; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, United States.
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Źródło :
ELife [Elife] 2020 Oct 15; Vol. 9. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Brain/*metabolism
Galectin 3/*genetics
Mice/*physiology
Microglia/*metabolism
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/*genetics
Signal Transduction/*genetics
Animals ; Female ; Galectin 3/metabolism ; Homeostasis ; Male ; Mice/genetics ; Mice, Inbred C57BL ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/metabolism
Czasopismo naukowe
Tytuł :
Atherosclerotic plaque injury-mediated murine thrombosis models: advantages and limitations.
Autorzy :
Karel M; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University , Maastricht, the Netherlands.
Hechler B; Université de Strasbourg, INSERM, Etablissement Français du Sang (EFS)-Grand Est, BPPS UMR_S 1255, Fédération de Médecine Translationnelle de Strasbourg (FMTS).
Kuijpers M; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University , Maastricht, the Netherlands.
Cosemans J; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University , Maastricht, the Netherlands.
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Źródło :
Platelets [Platelets] 2020 May 18; Vol. 31 (4), pp. 439-446. Date of Electronic Publication: 2020 Jan 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Models, Animal*
Mice*
Plaque, Atherosclerotic*/chemically induced
Plaque, Atherosclerotic*/pathology
Carotid Artery Thrombosis/*etiology
Animals ; Atherosclerosis/chemically induced ; Atherosclerosis/genetics ; Blood Coagulation ; Blood Platelets/metabolism ; Blood Platelets/physiology ; Carotid Artery Thrombosis/chemically induced ; Carotid Artery Thrombosis/metabolism ; Chlorides/toxicity ; Diet, High-Fat ; Ferric Compounds/toxicity ; Humans ; Ligation ; Mice, Knockout, ApoE ; Ultrasonic Waves
Czasopismo naukowe
Tytuł :
[Construction of transgenic mice with specific Cre recombinase expression in the zona fasciculata in adrenal cortex].
Autorzy :
Zhang NN; Department of Physiology, Navy Medical University, Shanghai 200433, China.
Wang CN; Department of Physiology, Navy Medical University, Shanghai 200433, China.
Ni X; Department of Physiology, Navy Medical University, Shanghai 200433, China.; Research Centre for Molecular Metabolomics, Xiangya Hospital, Central Southern University, Changsha 410008, China. .
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Źródło :
Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2020 Apr 25; Vol. 72 (2), pp. 148-156.
Typ publikacji :
Journal Article
MeSH Terms :
Mice, Transgenic*
Adrenal Cortex/*enzymology
Integrases/*metabolism
Zona Fasciculata/*enzymology
Animals ; CRISPR-Cas Systems ; Cystathionine gamma-Lyase/genetics ; Integrases/genetics ; Mice
Czasopismo naukowe

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