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Wyszukujesz frazę ""micronucleus"" wg kryterium: Temat


Tytuł:
Acute, subchronic toxicity and genotoxicity studies of JointAlive, a traditional Chinese medicine formulation for knee osteoarthritis.
Autorzy:
Wang Y; Chenland Nutritionals, Inc., Irvine, California, United States of America.
Li L; Chenland Nutritionals, Inc., Irvine, California, United States of America.
Mu Y; School of Pharmacy and Pharmaceutical Sciences, Shandong First Medical University, Jinan, Shandong, China.
Wang S; Chenland Nutritionals, Inc., Irvine, California, United States of America.
Li X; Chenland Research Institute, Qingdao City, Shandong Province, China.
Zong J; Chenland Research Institute, Qingdao City, Shandong Province, China.
Zou S; Chenland Research Institute, Qingdao City, Shandong Province, China.
Liu Z; Chenland Nutritionals, Inc., Irvine, California, United States of America.
Gao D; School of Pharmacy and Pharmaceutical Sciences, Shandong First Medical University, Jinan, Shandong, China.
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Źródło:
PloS one [PLoS One] 2023 Oct 17; Vol. 18 (10), pp. e0292937. Date of Electronic Publication: 2023 Oct 17 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Osteoarthritis, Knee*/drug therapy
Biological Products*
Rats ; Male ; Female ; Mice ; Animals ; Rats, Sprague-Dawley ; Mutagenicity Tests/methods ; Medicine, Chinese Traditional ; Micronucleus Tests ; Toxicity Tests, Acute ; Plant Extracts
Czasopismo naukowe
Tytuł:
Genotoxicity Evaluation of The Novel Psychoactive Substance MTTA.
Autorzy:
Lenzi M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
Gasperini S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
Corli G; Department of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.
Marti M; Department of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.; Collaborative Center for the Italian National Early Warning System, Department of Anti-Drug Policies, Presidency of the Council of Ministers, 00186 Rome, Italy.
Hrelia P; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 22; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Mutagens*/toxicity
Mutagens*/metabolism
DNA Damage*
Animals ; Micronucleus Tests/methods ; Central Nervous System Agents ; Mutagenicity Tests/methods ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Short Assay Design for Micronucleus Detection in Human Lymphocytes.
Autorzy:
Rincón G; Applied Science, Antonio Nariño University, Bogotá, Colombia.
Sánchez C; Applied Science, Antonio Nariño University, Bogotá, Colombia.
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Źródło:
BioMed research international [Biomed Res Int] 2021 Sep 11; Vol. 2021, pp. 2322257. Date of Electronic Publication: 2021 Sep 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Micronuclei, Chromosome-Defective*
Lymphocytes/*metabolism
Micronucleus Tests/*methods
Humans ; Micronucleus Tests/ethics ; Reproducibility of Results ; Statistics as Topic
Czasopismo naukowe
Tytuł:
Evaluation of Systemic Genotoxic/Oxidative and Proinflammatory Effects in Workers of a Titanium Dioxide Production Plant.
Autorzy:
Cavallo D; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Fresegna AM; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Ciervo A; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Maiello R; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Chiarella P; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Buresti G; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Del Frate V; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Di Basilio M; Department of Technological Innovation and Safety of Plants, Products and Anthropic Settlements, INAIL, Monte Porzio Catone, Rome, Italy.
Iavicoli S; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
Ursini CL; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL, Monte Porzio Catone, Rome, Italy.
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Źródło:
BioMed research international [Biomed Res Int] 2023 Jul 22; Vol. 2023, pp. 7066090. Date of Electronic Publication: 2023 Jul 22 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Occupational Exposure*/adverse effects
Occupational Exposure*/analysis
Humans ; Interleukin-8/genetics ; Mouth Mucosa ; Micronucleus Tests ; DNA Damage/genetics ; Titanium/toxicity ; Comet Assay ; Oxidative Stress/genetics ; X-ray Repair Cross Complementing Protein 1
Czasopismo naukowe
Tytuł:
An Evaluation of the Cytotoxic and Genotoxic Effects of the Marine Toxin C17-SAMT in Human TK6 and HepaRG Cell Lines.
Autorzy:
Marzougui Z; Laboratoire des Venins et Biomolécules Thérapeutiques, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère 1002, Tunisia.; Institut National Agronomique de Tunisie, Université de Carthage, Tunis 1082, Tunisia.
Le Hegarat L; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
Hogeveen K; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
Huet S; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
Kharrat R; Laboratoire des Venins et Biomolécules Thérapeutiques, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère 1002, Tunisia.
Marrouchi R; Laboratoire des Venins et Biomolécules Thérapeutiques, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère 1002, Tunisia.
Fessard V; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 25; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
Mycotoxins*
Humans ; Cell Line ; Mutagens/toxicity ; Marine Toxins/toxicity ; DNA Damage ; Micronucleus Tests/methods
Czasopismo naukowe
Tytuł:
Assessment of the genotoxic effects of antihypertensive drug active ingredient indapamide in human lymphocytes.
Autorzy:
Avuloglu-Yilmaz E; Vocational School of Technical Sciences, Amasya University, Amasya, Turkey.
Yuzbasioglu D; Department of Biology, Faculty of Science, Genetic Toxicology Laboratory, Gazi University, Ankara, Turkey.
Unal F; Department of Biology, Faculty of Science, Genetic Toxicology Laboratory, Gazi University, Ankara, Turkey.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2023 Mar; Vol. 46 (2), pp. 297-303. Date of Electronic Publication: 2022 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antihypertensive Agents*/toxicity
Indapamide*/toxicity
Humans ; Micronucleus Tests ; DNA Damage ; Lymphocytes ; Mitomycin
Czasopismo naukowe
Tytuł:
Flow cytometry as an alternative method to evaluate genotoxicity of natural cosmetic actives.
Autorzy:
Ueoka AR; Instituto de Ciências Ambientais Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.
Sufi BS; Chemyunion LTDA, Sorocaba, SP, Brazil.
Magalhães WV; Chemyunion LTDA, Sorocaba, SP, Brazil.
Fernandes L; Instituto de Ciências Ambientais Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.
Andreo-Filho N; Instituto de Ciências Ambientais Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.
Leite-Silva VR; Instituto de Ciências Ambientais Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.
Lopes PS; Instituto de Ciências Ambientais Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2023 Mar; Vol. 22 (3), pp. 958-968. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Caffeine*
Cosmetics*
Animals ; Flow Cytometry/methods ; Micronucleus Tests/methods ; DNA Damage ; Mammals
Czasopismo naukowe
Tytuł:
Transforming early pharmaceutical assessment of genotoxicity: applying statistical learning to a high throughput, multi end point in vitro micronucleus assay.
Autorzy:
Wilson A; Functional and Mechanistic Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK. .
Grabowski P; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Elloway J; Functional and Mechanistic Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Ling S; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Stott J; MAG-O, Manchester Airport, Manchester, UK.
Doherty A; Functional and Mechanistic Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 28; Vol. 11 (1), pp. 2535. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Drug-Related Side Effects and Adverse Reactions*
Mutagenicity Tests*/methods
Mutagenicity Tests*/standards
Micronucleus Tests/*methods
High-Throughput Screening Assays/methods ; High-Throughput Screening Assays/standards ; Humans ; Machine Learning ; Micronucleus Tests/standards ; Models, Statistical ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Hepatoprotective effect of the radiation countermeasure flagellin in the long term after irradiation of mice.
Autorzy:
Sycheva LP; State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
Rozhdestvenskii LM; State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
Lisina NI; State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
Shliakova TG; State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
Zorin VV; State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
Romanova KY; State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2023; Vol. 99 (2), pp. 238-244. Date of Electronic Publication: 2022 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Flagellin*/pharmacology
Radiation, Ionizing*
Mice ; Male ; Animals ; Dose-Response Relationship, Radiation ; Micronucleus Tests ; Gamma Rays/adverse effects
Czasopismo naukowe
Tytuł:
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytes in vitro .
Autorzy:
Akbas E; Genetic Toxicology Laboratory, Department of Biology, Science Faculty, Gazi University, 06560, Ankara, Turkey.
Unal F; Genetic Toxicology Laboratory, Department of Biology, Science Faculty, Gazi University, 06560, Ankara, Turkey.
Yuzbasioglu D; Genetic Toxicology Laboratory, Department of Biology, Science Faculty, Gazi University, 06560, Ankara, Turkey.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Nov; Vol. 45 (6), pp. 2471-2482. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Contrast Media*/toxicity
Gadolinium*/pharmacology
Humans ; Micronucleus Tests ; Sister Chromatid Exchange ; Lymphocytes ; DNA Damage ; Chromosome Aberrations/chemically induced ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł:
Micronucleus Assay: The State of Art, and Future Directions.
Autorzy:
Sommer S; Centre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warszawa, Poland.
Buraczewska I; Centre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warszawa, Poland.
Kruszewski M; Centre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warszawa, Poland.; Department of Molecular Biology and Translational Research, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Feb 24; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lymphocytes/*drug effects
Micronuclei, Chromosome-Defective/*drug effects
Micronucleus Tests/*methods
Mutagenicity Tests/*methods
Mutagens/*pharmacology
DNA Damage ; Forecasting ; Humans ; Lymphocytes/metabolism ; Lymphocytes/radiation effects ; Micronuclei, Chromosome-Defective/radiation effects ; Micronucleus Tests/trends ; Radiation, Ionizing
Czasopismo naukowe
Tytuł:
An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability.
Autorzy:
Lepage CC; Department of Biochemistry & Medical Genetics, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.; Research Institute in Oncology and Hematology, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada.
Thompson LL; Department of Biochemistry & Medical Genetics, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.; Research Institute in Oncology and Hematology, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada.
Larson B; BioTek Instruments, Inc., Winooski, VT 05404, USA.
McManus KJ; Department of Biochemistry & Medical Genetics, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.; Research Institute in Oncology and Hematology, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada.
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Źródło:
Cells [Cells] 2020 Feb 02; Vol. 9 (2). Date of Electronic Publication: 2020 Feb 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Imaging, Three-Dimensional*
Micronucleus Tests*
Microscopy*
Single-Cell Analysis*
Chromosomal Instability/*genetics
DNA Damage/*genetics
Automation ; Bleomycin/pharmacology ; Etoposide/pharmacology ; Gene Silencing/drug effects ; HCT116 Cells ; Humans
Czasopismo naukowe
Tytuł:
Assessment of micronuclei counts as tumour marker in cervical carcinogenesis: A follow-up study.
Autorzy:
Srivastava AN; Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, India.
Misra JS; Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, India.
Ahmad R; Department of Biochemistry, Era's Lucknow Medical College and Hospital, Era University, Lucknow, India.
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Źródło:
Cytopathology : official journal of the British Society for Clinical Cytology [Cytopathology] 2020 Jul; Vol. 31 (4), pp. 292-297.
Typ publikacji:
Journal Article
MeSH Terms:
Early Detection of Cancer*
Micronucleus Tests*
Papillomavirus Infections/*diagnosis
Uterine Cervical Neoplasms/*diagnosis
Adult ; Biomarkers, Tumor/genetics ; Carcinogenesis/genetics ; Female ; Follow-Up Studies ; Human Papillomavirus DNA Tests ; Humans ; India/epidemiology ; Papanicolaou Test ; Papillomaviridae/isolation & purification ; Papillomaviridae/pathogenicity ; Papillomavirus Infections/genetics ; Papillomavirus Infections/virology ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/pathology ; Vaginal Smears
Czasopismo naukowe
Tytuł:
Micronuclei in germ cells of hybrid frogs from Pelophylax esculentus complex contain gradually eliminated chromosomes.
Autorzy:
Dedukh D; Saint-Petersburg State University, Saint-Petersburg, Russia.
Riumin S; Saint-Petersburg State University, Saint-Petersburg, Russia.
Chmielewska M; Amphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.
Rozenblut-Kościsty B; Amphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.
Kolenda K; Amphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.
Kaźmierczak M; Amphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.
Dudzik A; Amphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.
Ogielska M; Amphibian Biology Group, Department of Evolutionary Biology and Conservation of Vertebrates, Faculty of Biological Sciences, University of Wrocław, Wrocław, Poland.
Krasikova A; Saint-Petersburg State University, Saint-Petersburg, Russia. .
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Źródło:
Scientific reports [Sci Rep] 2020 May 26; Vol. 10 (1), pp. 8720. Date of Electronic Publication: 2020 May 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosomes/*genetics
Micronucleus, Germline/*genetics
Rana esculenta/*genetics
Animals ; Centromere/genetics ; Centromere/metabolism ; Chimera/genetics ; Chromosomes/metabolism ; Evolution, Molecular ; Female ; Germ Cells/chemistry ; In Situ Hybridization, Fluorescence ; Male ; Micronucleus, Germline/metabolism ; Microtubule-Associated Proteins/metabolism
Czasopismo naukowe
Tytuł:
DNA damage induced by exposure to pesticides in children of rural areas in Paraguay.
Autorzy:
Leite SB; Department of Community Medicine, Faculty of Health Sciences of Catholic University 'Nuestra Señora de la Asunción', Asuncion, Paraguay.
Franco de Diana DM; Toxicological Genetics Laboratory of Faculty of Health Sciences of Catholic University 'Nuestra Señora de la Asunción', Asuncion, Paraguay.
Segovia Abreu JA; Toxicological Genetics Laboratory of Faculty of Health Sciences of Catholic University 'Nuestra Señora de la Asunción', Asuncion, Paraguay.
Avalos DS; Educational and Research Area of the General Directorate of Primary Health Care, Ministry of Public Health & Social Welfare, Asuncion, Paraguay.
Denis MA; Servicio Paz y Justicia Paraguay, Asuncion, Paraguay.
Ovelar CC; Servicio Paz y Justicia Paraguay, Asuncion, Paraguay.
Samaniego Royg MJ; Toxicological Genetics Laboratory of Faculty of Health Sciences of Catholic University 'Nuestra Señora de la Asunción', Asuncion, Paraguay.
Thielmann Arbo BA; Toxicological Genetics Laboratory of Faculty of Health Sciences of Catholic University 'Nuestra Señora de la Asunción', Asuncion, Paraguay.
Corvalan R; Servicio Paz y Justicia Paraguay, Asuncion, Paraguay.
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Źródło:
The Indian journal of medical research [Indian J Med Res] 2019 Sep; Vol. 150 (3), pp. 290-296.
Typ publikacji:
Journal Article
MeSH Terms:
Comet Assay*
DNA Damage*
Environmental Exposure*
Micronucleus Tests*
Pesticides/*adverse effects
Agriculture ; Biomarkers ; Cell Death ; Child ; Child, Preschool ; Cholinesterases/blood ; DNA/analysis ; Female ; Humans ; Male ; Mouth Mucosa/drug effects ; Paraguay/epidemiology ; Plants, Genetically Modified ; Rural Population
Czasopismo naukowe
Tytuł:
Comparative study of micronucleus assays and dicentric plus ring chromosomes for dose assessment in particular cases of partial-body exposure.
Autorzy:
Mendes ME; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.; b Department of Genetics, Federal University of Pernambuco , Recife , Brazil.
Mendonça JCG; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
Barquinero JF; c Department of Animal Biology, Plant Biology and Ecology, Faculty of Biosciences, Autonomous University of Barcelona , Bellaterra , Spain.
Higueras M; d Department of Mathematics and Computation, University of La Rioja , Logroño , Spain.
Gonzalez JE; e Center for Radiation Protection and Hygiene (CPHR) , La Havana , Cuba.
Andrade AMG; b Department of Genetics, Federal University of Pernambuco , Recife , Brazil.
Silva LM; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
Nascimento AMS; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
Lima JCF; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
Silva JCG; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
Hwang S; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
Melo AMMA; f Department of Biophysics and Radiobiology, Federal University of Pernambuco , Recife , Brazil.
Santos N; b Department of Genetics, Federal University of Pernambuco , Recife , Brazil.
Lima FF; a Regional Center of Nuclear Sciences of the Northeast (CRCN-NE) , Recife , Brazil.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2019 Aug; Vol. 95 (8), pp. 1058-1071. Date of Electronic Publication: 2019 Jun 03.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Micronucleus Tests*
Radiation Dosage*
Ring Chromosomes*
Chromosome Aberrations ; Dose-Response Relationship, Radiation ; Humans ; Poisson Distribution
Czasopismo naukowe
Tytuł:
Evaluation of Genotoxic Effect and Antigenotoxic Potential against DNA Damage of the Aqueous and Ethanolic Leaf Extracts of Annona muricata Using an In Vivo Erythrocyte Rodent Micronucleus Assay.
Autorzy:
Sánchez-De-La-Rosa SV; Instituto de Investigación en Odontología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Lazalde-Ramos BP; Maestría en Ciencias y Tecnología Química, Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98000, Mexico.
Morales-Velazquez G; Instituto de Investigación en Odontología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Zúñiga-González GM; Laboratorio de Mutagenesis, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.
Gómez-Meda BC; Instituto de Genética Humana 'Enrique Corona Rivera' Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Sánchez-Rivera SO; Instituto de Investigación en Odontología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Ortiz-García YM; Instituto de Investigación en Odontología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Guerrero-Velazquez C; Instituto de Investigación en Odontología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Zamora-Perez AL; Instituto de Investigación en Odontología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Dec 16; Vol. 2022, pp. 9554011. Date of Electronic Publication: 2022 Dec 16 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Plant Extracts*/therapeutic use
Annona*
Mice ; Rats ; Animals ; Rodentia ; Rats, Wistar ; Micronucleus Tests ; Erythrocytes ; DNA Damage ; Plant Leaves
Czasopismo naukowe
Tytuł:
A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays.
Autorzy:
Shuryak I; Center for Radiological Research, Columbia University Irving Medical Center, 630 West 168th Street, VC-11-234/5, New York, NY, 10032, USA. .
Royba E; Center for Radiological Research, Columbia University Irving Medical Center, 630 West 168th Street, VC-11-234/5, New York, NY, 10032, USA.
Repin M; Center for Radiological Research, Columbia University Irving Medical Center, 630 West 168th Street, VC-11-234/5, New York, NY, 10032, USA.
Turner HC; Center for Radiological Research, Columbia University Irving Medical Center, 630 West 168th Street, VC-11-234/5, New York, NY, 10032, USA.
Garty G; Radiological Research Accelerator Facility, Columbia University Irving Medical Center, Irvington, NY, USA.
Deoli N; Radiological Research Accelerator Facility, Columbia University Irving Medical Center, Irvington, NY, USA.
Brenner DJ; Center for Radiological Research, Columbia University Irving Medical Center, 630 West 168th Street, VC-11-234/5, New York, NY, 10032, USA.
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 06; Vol. 12 (1), pp. 21077. Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Machine Learning*
Humans ; Micronucleus Tests ; Cytogenetics ; Chromosomes
Czasopismo naukowe
Tytuł:
Changes in Radiosensitivity to Gamma-Rays of Lymphocytes from Hyperthyroid Patients Treated with I-131.
Autorzy:
Dini V; National Center for Innovative Technologies in Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.; Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Roma1, Department of Physics, University La Sapienza, 00185 Rome, Italy.
Salvatori M; Nuclear Medicine Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Belli M
Lago ME; Nuclear Medicine Unit, ARNAS Garibaldi-P.O. Nesima, 95122 Catania, Italy.
Nosdeo A
Dambra DP; Associazione Donatori Sangue 'La Rete di Tutti', 00145 Rome, Italy.
Lo Conte L; Nuclear Medicine Unit, 'Vito Fazzi' Hospital, 73100 Lecce, Italy.
Pecchia I; National Center for Innovative Technologies in Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Giordano A; Nuclear Medicine Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 05; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperthyroidism*/radiotherapy
Iodine Radioisotopes*/therapeutic use
Dose-Response Relationship, Radiation ; Humans ; Lymphocytes ; Micronucleus Tests ; Radiation Tolerance
Czasopismo naukowe
Tytuł:
Protective effect of chrysin, a flavonoid, on the genotoxic activity of carboplatin in mice.
Autorzy:
Jan BL; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ahmad A; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Khan A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Rehman MU; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Alkharfy KM; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Sep; Vol. 45 (5), pp. 2146-2152. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
DNA Damage*
Animals ; Carboplatin/toxicity ; Comet Assay/methods ; DNA ; Flavonoids/pharmacology ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Micronucleus Tests
Czasopismo naukowe
Tytuł:
Investigation of genotoxic effects of rhododendron honey using three mammalian bioassays in vivo .
Autorzy:
Rasgele PG; Department of Biosystems Engineering, Faculty of Agriculture, Duzce University, Duzce, Turkey.
Gokalp FD; Department of Biology, Faculty of Science, Trakya University, Edirne, Turkey.
Kaya ST; Department of Biology, Faculty of Science and Letters, Duzce University, Duzce, Turkey.
Kekecoglu M; Department of Biology, Faculty of Science and Letters, Duzce University, Duzce, Turkey.
Acar MK; Duzce Vocational School, Duzce University, Duzce, Turkey.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Sep; Vol. 45 (5), pp. 2301-2310. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji:
Journal Article
MeSH Terms:
Honey*/analysis
Rhododendron*/chemistry
Animals ; Biological Assay ; DNA Damage ; Humans ; Male ; Mammals ; Mice ; Micronucleus Tests ; Seeds
Czasopismo naukowe
Tytuł:
A follow-up study on workers involved in the graphene production process after the introduction of exposure mitigation measures: evaluation of genotoxic and oxidative effects.
Autorzy:
Cavallo D; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Ursini CL; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Fresegna AM; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Ciervo A; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Boccuni F; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Ferrante R; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Tombolini F; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Maiello R; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Chiarella P; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Buresti G; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Del Frate V; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Poli D; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
Andreoli R; Department of Medicine and Surgery, Laboratory of Industrial Toxicology, University of Parma, Parma, Italy.
Di Cristo L; Italian Institute of Technology-IIT, Genova, Italy.
Sabella S; Italian Institute of Technology-IIT, Genova, Italy.
Iavicoli S; Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers' Compensation Authority-INAIL, Rome, Italy.
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Źródło:
Nanotoxicology [Nanotoxicology] 2022 Aug-Oct; Vol. 16 (6-8), pp. 776-790. Date of Electronic Publication: 2022 Nov 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Occupational Exposure*/analysis
Graphite*/toxicity
Humans ; Follow-Up Studies ; 8-Hydroxy-2'-Deoxyguanosine ; Micronucleus Tests/methods ; Biomarkers ; DNA Damage ; Oxidative Stress ; Comet Assay
Czasopismo naukowe
Tytuł:
Quantitative relationships between acentric fragments and micronuclei: new models and implications for curve fitting.
Autorzy:
Udroiu I; Dipartimento di Scienze, Università degli Studi 'Roma Tre', Rome, Italy.
Sgura A; Dipartimento di Scienze, Università degli Studi 'Roma Tre', Rome, Italy.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2020 Feb; Vol. 96 (2), pp. 197-205. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Micronucleus Tests*
Cell Nucleus/*metabolism
Chromosome Aberrations/*radiation effects
Micronuclei, Chromosome-Defective/*radiation effects
Apoptosis ; DNA Damage ; Dose-Response Relationship, Radiation ; Epithelial Cells/radiation effects ; Fibroblasts/radiation effects ; Humans ; Kinetics ; Linear Models ; Metaphase ; Probability ; Telophase
Czasopismo naukowe
Tytuł:
Associating Air Pollution with Cytokinesis-Block Micronucleus Assay Parameters in Lymphocytes of the General Population in Zagreb (Croatia).
Autorzy:
Gajski G; Mutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Gerić M; Mutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Pehnec G; Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Matković K; Mutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Rinkovec J; Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Jakovljević I; Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Godec R; Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Žužul S; Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Bešlić I; Environmental Hygiene Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Cvitković A; Teaching Institute of Public Health Brod-Posavina County, 35000 Slavonski Brod, Croatia.; Faculty of Dental Medicine and Health, J. J. Strossmayer University of Osijek, 31000 Osijek, Croatia.; Faculty of Medicine, J. J. Strossmayer University of Osijek, 31000 Osijek, Croatia.
Wild P; Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1011 Lausanne, Switzerland.; PW Statistical Consulting, 54520 Laxou, France.
Guseva Canu I; Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1011 Lausanne, Switzerland.
Hopf NB; Center for Primary Care and Public Health (Unisanté), University of Lausanne, 1011 Lausanne, Switzerland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 03; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 03.
Typ publikacji:
Journal Article
MeSH Terms:
Air Pollution*/adverse effects
Cytokinesis*
Croatia ; Cross-Sectional Studies ; DNA Damage ; Humans ; Lymphocytes ; Micronucleus Tests/methods ; Prospective Studies
Czasopismo naukowe
Tytuł:
Genotoxicity evaluation of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle for the treatment of fibrotic disease.
Autorzy:
Kim HY; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Kim TR; siRNAgen therapeutics and Bioneer Corporation, Daejeon, Republic of Korea.
Kim SH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Kim IH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Ko Y; siRNAgen therapeutics and Bioneer Corporation, Daejeon, Republic of Korea.
Yun S; siRNAgen therapeutics and Bioneer Corporation, Daejeon, Republic of Korea.
Lee IC; Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea.
Park HO; siRNAgen therapeutics and Bioneer Corporation, Daejeon, Republic of Korea.
Kim JC; College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Sep; Vol. 45 (5), pp. 2109-2115. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji:
Journal Article
MeSH Terms:
Micelles*
Nanoparticles*/toxicity
Amphiregulin/genetics ; Animals ; Chromosome Aberrations ; Cricetinae ; Cricetulus ; Escherichia coli/genetics ; Mice ; Mice, Inbred ICR ; Micronucleus Tests ; Mutagenicity Tests ; RNA, Small Interfering/genetics
Czasopismo naukowe

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