- Tytuł :
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Genome-wide analysis of 102,084
migraine cases identifies 123 risk loci and subtype-specific risk alleles. - Autorzy :
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Hautakangas H; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Winsvold BS; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway.
Ruotsalainen SE; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Bjornsdottir G; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Harder AVE; Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
Kogelman LJA; Danish Headache Center, Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark.
Thomas LF; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; BioCore - Bioinformatics Core Facility, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
Benner C; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Gormley P; GlaxoSmithKline, Cambridge, MA, USA.
Artto V; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.
Banasik K; Novo Nordic Foundation Center for Protein Research, Copenhagen University, Copenhagen, Denmark.
Bjornsdottir A; Neurology Private Practice, Laeknasetrid, Reykjavik, Iceland.
Boomsma DI; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Brumpton BM; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Burgdorf KS; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Chalmer MA; Danish Headache Center, Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark.
de Boer I; Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.
Dichgans M; Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (Synergy), Munich, Germany.
Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
Färkkilä M; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.
Garbrielsen ME; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Ghanbari M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Hagen K; Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Clinical Research Unit Central Norway, St. Olavs University Hospital, Trondheim, Norway.
Häppölä P; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Hottenga JJ; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Hrafnsdottir MG; Landspitali University Hospital, Reykjavik, Iceland.
Hveem K; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Johnsen MB; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Kristoffersen ES; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.; Department of Neurology, Akershus University Hospital, Lørenskog, Norway.
Kurth T; Institute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Lighart L; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Magnusson SH; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Malik R; Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany.
Pedersen OB; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.
Pelzer N; Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.
Penninx BWJH; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; GGZ inGeest Specialized Mental Health Care, Amsterdam, the Netherlands.
Ran C; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Sigurdardottir GR; Neurology Private Practice, Laeknasetrid, Reykjavik, Iceland.
Skogholt AH; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Sveinsson OA; Landspitali University Hospital, Reykjavik, Iceland.
Thorgeirsson TE; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Ullum H; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Vijfhuizen LS; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
Widén E; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
van Dijk KW; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.
Aromaa A; National Public Health Institute (Finnish Institute for Health and Welfare - THL), Helsinki, Finland.
Belin AC; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Freilinger T; Klinikum Passau, Department of Neurology, Passau, Germany.; Centre of Neurology, Hertie Institute for Clinical Brain Research, Tuebingen, Germany.
Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Järvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.
Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
Terwindt GM; Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.
Kallela M; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.
Wessman M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.
Olesen J; Danish Headache Center, Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Nyholt DR; School of Biomedical Sciences and Centre for Genomics and Personalised Health, Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia.
Stefánsson H; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
Stefansson K; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
van den Maagdenberg AMJM; Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
Hansen TF; Danish Headache Center, Department of Neurology, Copenhagen University Hospital, Copenhagen, Denmark.; Novo Nordic Foundation Center for Protein Research, Copenhagen University, Copenhagen, Denmark.
Ripatti S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland.
Zwart JA; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Palotie A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Pirinen M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland. .; Department of Public Health, University of Helsinki, Helsinki, Finland. .; Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland. . - Pokaż więcej
- Corporate Authors :
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International Headache Genetics Consortium
HUNT All-in Headache
Danish Blood Donor Study Genomic Cohort - Źródło :
- Nature genetics [Nat Genet] 2022 Feb; Vol. 54 (2), pp. 152-160. Date of Electronic Publication: 2022 Feb 03.
- Typ publikacji :
- Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms :
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Genetic Predisposition to Disease*
Genome-Wide Association Study*
Polymorphism, Single Nucleotide*Migraine Disorders/*genetics
Alleles ; Cardiovascular System/metabolism ; Case-Control Studies ; Central Nervous System/metabolism ; Genetic Loci ; Humans ;Migraine with Aura/genetics ; Molecular Sequence Annotation ; Quantitative Trait Loci -
Czasopismo naukowe
Na półce