MDS is a relatively common mitochondrial disease affecting infants and children. Age at onset varies in the different forms of the disease. In the hepatocerebral form, the onset is from birth to six months, and death occurs in the first year due to hepatic failure. In the myopathic form, onset is from birth to two years, and death typically occurs in infancy or childhood due to respiratory failure. A benign late-onset form occurs between one week and five years of age, and death typically... więcej

Salem Press Encyclopedia of Health, 2023. 2p.