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Tytuł :
Lubiprostone in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled, phase 2a trial.
Autorzy :
Kessoku T; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; Department of Palliative Medicine, Yokohama City University Hospital, Yokohama, Japan.
Imajo K; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kobayashi T; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Ozaki A; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Iwaki M; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Honda Y; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; Department of Palliative Medicine, Yokohama City University Hospital, Yokohama, Japan.
Kato T; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; Department of Gastroenterology, International University of Health and Welfare Atami Hospital, Atami, Japan.
Ogawa Y; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Tomeno W; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; Department of Gastroenterology, International University of Health and Welfare Atami Hospital, Atami, Japan.
Kato S; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Higurashi T; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yoneda M; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kirikoshi H; Clinical Laboratory Department, Yokohama City University Hospital, Yokohama, Japan.
Kubota K; Department of Biostatistics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Taguri M; Department of Data Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yamanaka T; Department of Biostatistics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Usuda H; Department of Pharmacology, Shimane University Faculty of Medicine, Izumo, Japan.
Wada K; Department of Pharmacology, Shimane University Faculty of Medicine, Izumo, Japan.
Kobayashi N; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; Department of Oncology, Yokohama City University Hospital, Yokohama, Japan.
Saito S; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Nakajima A; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan. Electronic address: .
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Źródło :
The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2020 Nov; Vol. 5 (11), pp. 996-1007. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Diarrhea*/chemically induced
Diarrhea*/diagnosis
Liver*/diagnostic imaging
Liver*/metabolism
Lubiprostone*/administration & dosage
Lubiprostone*/adverse effects
Non-alcoholic Fatty Liver Disease*/blood
Non-alcoholic Fatty Liver Disease*/complications
Non-alcoholic Fatty Liver Disease*/physiopathology
Alanine Transaminase/*blood
Constipation/drug therapy ; Constipation/etiology ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug Monitoring/methods ; Elasticity Imaging Techniques/methods ; Female ; Humans ; Laxatives/administration & dosage ; Laxatives/adverse effects ; Liver Function Tests ; Male ; Middle Aged ; Treatment Outcome
Czasopismo naukowe
Tytuł :
HIV postexposure prophylaxis during COVID-19.
Autorzy :
Junejo M; 56 Dean Street, Chelsea and Westminster Hospital National Health Service Foundation Trust, London W1D 6AQ, UK.
Girometti N; 56 Dean Street, Chelsea and Westminster Hospital National Health Service Foundation Trust, London W1D 6AQ, UK.
McOwan A; 56 Dean Street, Chelsea and Westminster Hospital National Health Service Foundation Trust, London W1D 6AQ, UK.
Whitlock G; 56 Dean Street, Chelsea and Westminster Hospital National Health Service Foundation Trust, London W1D 6AQ, UK. Electronic address: .
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Corporate Authors :
Dean Street Collaborative Group
Źródło :
The lancet. HIV [Lancet HIV] 2020 Jul; Vol. 7 (7), pp. e460. Date of Electronic Publication: 2020 May 25.
Typ publikacji :
Letter
MeSH Terms :
Pandemics*/prevention & control
Anti-HIV Agents/*therapeutic use
Betacoronavirus/*pathogenicity
Coronavirus Infections/*epidemiology
HIV Infections/*epidemiology
HIV Infections/*prevention & control
Pneumonia, Viral/*epidemiology
Adult ; Coinfection ; Coronavirus Infections/prevention & control ; Coronavirus Infections/psychology ; Coronavirus Infections/transmission ; Drug Prescriptions/statistics & numerical data ; Female ; HIV/drug effects ; HIV/pathogenicity ; HIV Infections/psychology ; HIV Infections/transmission ; Humans ; Male ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/psychology ; Pneumonia, Viral/transmission ; Post-Exposure Prophylaxis/methods ; Post-Exposure Prophylaxis/statistics & numerical data ; Prescription Drug Monitoring Programs ; Sexual Partners/psychology ; Social Distance ; United Kingdom/epidemiology
SCR Disease Name :
COVID-19
Opinia redakcyjna
Tytuł :
The usefulness of HIV partner services in the age of treatment as prevention: a registry-based study.
Autorzy :
Udeagu CN; HIV Epidemiology Program, Bureau of HIV, New York City Department of Health and Mental Hygiene, New York, NY, USA. Electronic address: .
Shah S; HIV Epidemiology Program, Bureau of HIV, New York City Department of Health and Mental Hygiene, New York, NY, USA.
Misra K; HIV Epidemiology Program, Bureau of HIV, New York City Department of Health and Mental Hygiene, New York, NY, USA.
Xia Q; HIV Epidemiology Program, Bureau of HIV, New York City Department of Health and Mental Hygiene, New York, NY, USA.
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Źródło :
The lancet. HIV [Lancet HIV] 2020 Jul; Vol. 7 (7), pp. e482-e490.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Counseling*
Sexual Partners*
Anti-HIV Agents/*therapeutic use
HIV Infections/*prevention & control
Adolescent ; Adult ; CD4 Lymphocyte Count ; Epidemiological Monitoring ; Female ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; HIV Infections/transmission ; Humans ; Male ; Middle Aged ; New York City/epidemiology ; Public Health ; Registries ; Viral Load ; Young Adult
Czasopismo naukowe
Tytuł :
SARS-CoV-2 in wastewater: potential health risk, but also data source.
Autorzy :
Lodder W; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, 3720 BA Bilthoven, Netherlands.
de Roda Husman AM; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, 3720 BA Bilthoven, Netherlands. Electronic address: .
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Źródło :
The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2020 Jun; Vol. 5 (6), pp. 533-534. Date of Electronic Publication: 2020 Apr 01.
Typ publikacji :
Letter
MeSH Terms :
Betacoronavirus*
Coronavirus Infections/*epidemiology
Pneumonia, Viral/*epidemiology
Waste Water/*virology
Epidemiological Monitoring ; Humans ; Pandemics
SCR Disease Name :
COVID-19
Opinia redakcyjna
Tytuł :
Point-of-care HIV viral load testing combined with task shifting to improve treatment outcomes (STREAM): findings from an open-label, non-inferiority, randomised controlled trial.
Autorzy :
Drain PK; Department of Global Health, School of Public Health and School of Medicine, University of Washington, Seattle, WA, USA; Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA. Electronic address: .
Dorward J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
Violette LR; Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
Quame-Amaglo J; Department of Global Health, School of Public Health and School of Medicine, University of Washington, Seattle, WA, USA.
Thomas KK; Department of Global Health, School of Public Health and School of Medicine, University of Washington, Seattle, WA, USA.
Samsunder N; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
Ngobese H; Prince Cyril Zulu Communicable Disease Clinic, Durban Municipality, Durban, South Africa.
Mlisana K; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa; National Health Laboratory Service, Durban, South Africa.
Moodley P; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa; National Health Laboratory Service, Durban, South Africa; Department of Virology, Inkosi Albert Luthuli Central Hospital, Cato Manor, South Africa.
Donnell D; Department of Global Health, School of Public Health and School of Medicine, University of Washington, Seattle, WA, USA.
Barnabas RV; Department of Global Health, School of Public Health and School of Medicine, University of Washington, Seattle, WA, USA; Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
Naidoo K; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa; School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa; CAPRISA-MRC HIV-TB Pathogenesis and Treatment Research Unit, and Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Abdool Karim SS; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa; School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY, USA.
Celum C; Department of Global Health, School of Public Health and School of Medicine, University of Washington, Seattle, WA, USA; Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
Garrett N; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa; School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Pokaż więcej
Źródło :
The lancet. HIV [Lancet HIV] 2020 Apr; Vol. 7 (4), pp. e229-e237. Date of Electronic Publication: 2020 Feb 24.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
Viral Load/*drug effects
Adult ; Drug Monitoring ; Female ; HIV Infections/virology ; HIV-1/drug effects ; HIV-1/physiology ; Humans ; Male ; Point-of-Care Testing ; South Africa ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Dynamics of the HIV outbreak and response in Scott County, IN, USA, 2011-15: a modelling study.
Autorzy :
Gonsalves GS; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA; Yale Law School, New Haven, CT, USA. Electronic address: .
Crawford FW; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA; Operations Program, Yale School of Management, New Haven, CT, USA.
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Źródło :
The lancet. HIV [Lancet HIV] 2018 Oct; Vol. 5 (10), pp. e569-e577. Date of Electronic Publication: 2018 Sep 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Epidemiological Monitoring*
Models, Statistical*
Public Health*/methods
Disease Outbreaks/*prevention & control
HIV Infections/*epidemiology
HIV Infections/prevention & control ; Humans ; Incidence ; Indiana/epidemiology ; Time Factors
Czasopismo naukowe
Tytuł :
Health impact of China's Air Pollution Prevention and Control Action Plan: an analysis of national air quality monitoring and mortality data.
Autorzy :
Huang J; Department of Occupational and Environmental Health Sciences, Peking University School of Public Health, Beijing, China.
Pan X; Department of Occupational and Environmental Health Sciences, Peking University School of Public Health, Beijing, China.
Guo X; Department of Occupational and Environmental Health Sciences, Peking University School of Public Health, Beijing, China.
Li G; Department of Occupational and Environmental Health Sciences, Peking University School of Public Health, Beijing, China. Electronic address: .
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Źródło :
The Lancet. Planetary health [Lancet Planet Health] 2018 Jul; Vol. 2 (7), pp. e313-e323.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Environmental Monitoring*
Mortality*
Air Pollution/*legislation & jurisprudence
Air Pollution/*prevention & control
Air Pollutants/adverse effects ; Air Pollution/adverse effects ; Air Pollution/analysis ; China ; Cities ; Humans ; Life Expectancy
Czasopismo naukowe
Tytuł :
No association between HPV vaccine and reported post-vaccination symptoms in Japanese young women: Results of the Nagoya study.
Autorzy :
Suzuki S; Department of Public Health, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 466-8601, Japan. Electronic address: .
Hosono A; Department of Public Health, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 466-8601, Japan.
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Źródło :
Papillomavirus research (Amsterdam, Netherlands) [Papillomavirus Res] 2018 Jun; Vol. 5, pp. 96-103. Date of Electronic Publication: 2018 Feb 23.
Typ publikacji :
Journal Article
MeSH Terms :
Epidemiological Monitoring*
Adverse Drug Reaction Reporting Systems/*statistics & numerical data
Papillomavirus Vaccines/*adverse effects
Vaccination/*adverse effects
Adolescent ; Child ; Female ; Humans ; Immunization Programs ; Japan/epidemiology ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines/administration & dosage ; Surveys and Questionnaires ; Young Adult
Czasopismo naukowe
Tytuł :
Adherence to Active Surveillance Protocols for Low-risk Prostate Cancer: Results of the Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance Initiative.
Autorzy :
Kalapara AA; Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.
Verbeek JFM; Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands.
Nieboer D; Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands.
Fahey M; Epworth HealthCare, Melbourne, Victoria, Australia.
Gnanapragasam V; Academic Urology Group, Department of Surgery and Oncology, University of Cambridge, Cambridge, UK.
Van Hemelrijck M; Division of Cancer Studies, Translational Oncology & Urology Research, King's College London, London, UK.
Lee LS; Singapore General Hospital, Singapore, Singapore.
Bangma CH; Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands.
Steyerberg EW; Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands.
Harkin T; Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.
Helleman J; Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands.
Roobol MJ; Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands.
Frydenberg M; Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia; Department of Urology, Monash Health, Victoria, Australia. Electronic address: .
Pokaż więcej
Corporate Authors :
Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance (GAP3) Consortium
Źródło :
European urology oncology [Eur Urol Oncol] 2020 Feb; Vol. 3 (1), pp. 80-91. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Prostatic Neoplasms/*epidemiology
Aged ; Epidemiological Monitoring ; Humans ; Male ; Middle Aged ; Prostatic Neoplasms/pathology ; Risk Factors
Czasopismo naukowe
Tytuł :
Pharmacokinetics of TKM-130803 in Sierra Leonean patients with Ebola virus disease:  plasma concentrations exceed target levels, with drug accumulation in the most severe patients.
Autorzy :
Scott JT; MRC-University of Glasgow Centre for Virus Research, G61 1QH, UK; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Liverpool, Liverpool, UK. Electronic address: .
Sharma R; Liverpool School of Tropical Medicine, Liverpool, UK.
Meredith LW; Department of Pathology, Division of Virology, University of Cambridge, Cambridge CB2 1QP, UK; Department of Public Health, University of Makeni, Makeni, Sierra Leone.
Dunning J; National Infection Service, Public Health England, London, UK; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Moore CE; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Sahr F; Republic Sierra Leone Armed Forces, Military Hosp 34, Freetown, Sierra Leone.
Ward S; Liverpool School of Tropical Medicine, Liverpool, UK.
Goodfellow I; Department of Pathology, Division of Virology, University of Cambridge, Cambridge CB2 1QP, UK; Department of Public Health, University of Makeni, Makeni, Sierra Leone.
Horby P; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Pokaż więcej
Corporate Authors :
RAPIDE-TKM trial team; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Źródło :
EBioMedicine [EBioMedicine] 2020 Feb; Vol. 52, pp. 102601. Date of Electronic Publication: 2020 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacokinetics
Hemorrhagic Fever, Ebola/*drug therapy
Hemorrhagic Fever, Ebola/*virology
RNA, Small Interfering/*pharmacokinetics
Algorithms ; Antiviral Agents/administration & dosage ; Computer Simulation ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Drug Monitoring ; Hemorrhagic Fever, Ebola/diagnosis ; Hemorrhagic Fever, Ebola/mortality ; Humans ; Models, Theoretical ; RNA, Small Interfering/administration & dosage ; Severity of Illness Index ; Sierra Leone ; Treatment Outcome ; Viral Load
Czasopismo naukowe
Tytuł :
De-escalation of immunomodulator and biological therapy in inflammatory bowel disease.
Autorzy :
Chapman TP; Translational Gastroenterology Unit, Nuffield Department of Experimental Medicine, University of Oxford, Oxford, UK. Electronic address: .
Gomes CF; Surgical Department, Gastroenterology Division, Hospital Beatriz Ângelo, Loures, Portugal.
Louis E; Department of Gastroenterology, CHU Liège University Hospital, Liège, Belgium.
Colombel JF; The Dr Henry D Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Satsangi J; Translational Gastroenterology Unit, Nuffield Department of Experimental Medicine, University of Oxford, Oxford, UK.
Pokaż więcej
Źródło :
The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2020 Jan; Vol. 5 (1), pp. 63-79.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Therapy/*methods
Drug Monitoring/*methods
Immunologic Factors/*therapeutic use
Inflammatory Bowel Diseases/*therapy
Remission Induction/*methods
Humans
Czasopismo naukowe
Tytuł :
Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46).
Autorzy :
Panizza BJ; Department of Otolaryngology-Head and Neck Surgery, Princess Alexandra Hospital and Faculty of Medicine, University of Queensland, Brisbane, Australia. Electronic address: .
de Souza P; Medical Oncology, University of Western Sydney, Sydney, Australia.
Cooper A; Medical Oncology, University of Western Sydney, Sydney, Australia.
Roohullah A; Medical Oncology, University of Western Sydney, Sydney, Australia.
Karapetis CS; Department of Medical Oncology, Flinders Medical Center and Flinders Center for Innovation in Cancer, Flinders University, Adelaide, Australia.
Lickliter JD; Nucleus Network, Melbourne, Australia.
Pokaż więcej
Źródło :
EBioMedicine [EBioMedicine] 2019 Dec; Vol. 50, pp. 433-441. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Multicenter Study
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Antineoplastic Agents/*pharmacokinetics
Diterpenes/*administration & dosage
Diterpenes/*pharmacokinetics
Neoplasms/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/adverse effects ; Diterpenes/adverse effects ; Drug Monitoring ; Female ; Humans ; Injections, Intralesional ; Male ; Melanoma/diagnosis ; Melanoma/drug therapy ; Middle Aged ; Neoplasm Staging ; Neoplasms/diagnosis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Cancer risk in HIV-infected people in the USA from 1996 to 2012: a population-based, registry-linkage study.
Autorzy :
Hernández-Ramírez RU; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale School of Medicine, New Haven, CT, USA. Electronic address: .
Shiels MS; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Dubrow R; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale School of Medicine, New Haven, CT, USA.
Engels EA; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
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Źródło :
The lancet. HIV [Lancet HIV] 2017 Nov; Vol. 4 (11), pp. e495-e504. Date of Electronic Publication: 2017 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Epidemiological Monitoring*
Registries*
HIV Infections/*complications
Neoplasms/*etiology
Adult ; Age Factors ; Aged ; Antiretroviral Therapy, Highly Active/adverse effects ; Cohort Studies ; Female ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Humans ; Immunosuppression/adverse effects ; Incidence ; Lung Neoplasms/epidemiology ; Lung Neoplasms/etiology ; Lung Neoplasms/prevention & control ; Lymphoma, Non-Hodgkin/epidemiology ; Lymphoma, Non-Hodgkin/etiology ; Lymphoma, Non-Hodgkin/prevention & control ; Male ; Middle Aged ; Neoplasms/epidemiology ; Risk Factors ; Sarcoma, Kaposi/epidemiology ; Sarcoma, Kaposi/etiology ; Sarcoma, Kaposi/prevention & control ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Reducing Mortality in the Ageing Patient: Treatment of the Primary Tumour Is Not Necessary.
Autorzy :
Lamb AD; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: .
Brewster SF; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Hamdy FC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
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Źródło :
European urology focus [Eur Urol Focus] 2017 Oct; Vol. 3 (4-5), pp. 328-329. Date of Electronic Publication: 2017 Oct 31.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Aging/*physiology
Monitoring, Physiologic/*standards
Prostate/*pathology
Prostatectomy/*adverse effects
Prostatic Neoplasms/*pathology
Aged, 80 and over ; Clinical Decision-Making/ethics ; Humans ; Life Expectancy ; Lower Urinary Tract Symptoms/diagnosis ; Lower Urinary Tract Symptoms/therapy ; Male ; Monitoring, Physiologic/trends ; Mortality/trends ; Patient Outcome Assessment ; Patient Selection/ethics ; Prostate/surgery ; Prostatectomy/mortality ; Prostatic Neoplasms/mortality ; Prostatic Neoplasms/surgery ; Randomized Controlled Trials as Topic ; Transurethral Resection of Prostate/methods ; Urinary Incontinence/complications
Czasopismo naukowe
Tytuł :
Salsalate, but not metformin or canagliflozin, slows kidney cyst growth in an adult-onset mouse model of polycystic kidney disease.
Autorzy :
Leonhard WN; Department of Human Genetics, Leiden University Medical Centre, Leiden, the Netherlands.
Song X; Division of Nephrology, University Health Network, Toronto, Ontario, Canada; Division of Nephrology, University of Toronto, Toronto, Ontario, Canada.
Kanhai AA; Department of Human Genetics, Leiden University Medical Centre, Leiden, the Netherlands.
Iliuta IA; Division of Nephrology, University Health Network, Toronto, Ontario, Canada; Division of Nephrology, University of Toronto, Toronto, Ontario, Canada.
Bozovic A; Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Steinberg GR; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada.
Peters DJM; Department of Human Genetics, Leiden University Medical Centre, Leiden, the Netherlands. Electronic address: .
Pei Y; Division of Nephrology, University Health Network, Toronto, Ontario, Canada; Division of Nephrology, University of Toronto, Toronto, Ontario, Canada. Electronic address: .
Pokaż więcej
Źródło :
EBioMedicine [EBioMedicine] 2019 Sep; Vol. 47, pp. 436-445. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Cysts/*pathology
Polycystic Kidney Diseases/*pathology
Salicylates/*pharmacology
AMP-Activated Protein Kinases/metabolism ; Animals ; Biopsy ; Cyclic AMP/metabolism ; Cysts/drug therapy ; Cysts/genetics ; Cysts/metabolism ; Disease Models, Animal ; Drug Monitoring ; Metformin/pharmacology ; Mice ; Mice, Knockout ; Mutation ; Polycystic Kidney Diseases/drug therapy ; Polycystic Kidney Diseases/genetics ; Polycystic Kidney Diseases/metabolism ; Polycystic Kidney, Autosomal Dominant/drug therapy ; Polycystic Kidney, Autosomal Dominant/genetics ; Polycystic Kidney, Autosomal Dominant/metabolism ; Polycystic Kidney, Autosomal Dominant/pathology ; TRPP Cation Channels/genetics ; TRPP Cation Channels/metabolism
Czasopismo naukowe
Tytuł :
Drought: a global environmental concern.
Autorzy :
Kravitz JD; Independent Public Health Consultant, Portland, OR, USA. Electronic address: .
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Źródło :
The Lancet. Planetary health [Lancet Planet Health] 2017 Jul; Vol. 1 (4), pp. e130-e131. Date of Electronic Publication: 2017 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Climate Change*
Droughts*
Environmental Monitoring*
Conservation of Natural Resources/*methods
Czasopismo naukowe
Tytuł :
Comparison of dynamic monitoring strategies based on CD4 cell counts in virally suppressed, HIV-positive individuals on combination antiretroviral therapy in high-income countries: a prospective, observational study.
Autorzy :
Caniglia EC; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA. Electronic address: .
Cain LE; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Sabin CA; University College London, London, UK.
Robins JM; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
Logan R; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Abgrall S; Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France; Assistance Publique-Hopitaux de Paris (AP-HP), Hopital Antoine Béclère, Service de Médecine Interne, Clamart, France.
Mugavero MJ; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; UAB Center for AIDS Research, University of Alabama at Birmingham, Birmingham, AL, USA.
Hernández-Díaz S; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Meyer L; Université Paris Sud, INSERM CESP U1018, Paris, France; AP-HP, Hopital de Bicêtre, Service de Santé Publique, le Kremlin Bicêtre, France.
Seng R; Université Paris Sud, INSERM CESP U1018, Paris, France; AP-HP, Hopital de Bicêtre, Service de Santé Publique, le Kremlin Bicêtre, France.
Drozd DR; School of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.
Seage GR 3rd; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Bonnet F; Institut de Santé Publique, d'Epidémiologie et de Développement, Université de Bordeaux, Bordeaux, France; Department of Internal Medicine, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.
Dabis F; INSERM U897, Centre INSERM Epidémiologie et Biostatistique, Université de Bordeaux, Bordeaux, France; Department of Internal Medicine, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.
Moore RD; School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Reiss P; Stichting HIV Monitoring, Amsterdam, Netherlands; Academic Medical Center, Department of Global Health and Division of Infectious Diseases, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands.
van Sighem A; Stichting HIV Monitoring, Amsterdam, Netherlands.
Mathews WC; Internal Medicine, Johns Hopkins University, Baltimore, MD, USA.
Del Amo J; National Centre of Epidemiology, Instituto de Salud Carlos III, Madrid, Spain; Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Moreno S; Ramón y Cajal Hospital, IRYCIS, Madrid, Spain; University of Alcalá de Henares, Madrid, Spain.
Deeks SG; Positive Health Program, San Francisco General Hospital, San Francisco, CA, USA.
Muga R; Servei de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Spain.
Boswell SL; Fenway Health, Boston, MA, USA.
Ferrer E; Hospital Universitari de Bellvitge-Bellvitge Institute for Biomedical Research, Hospitalet de Llobregat, Barcelona, Spain.
Eron JJ; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Napravnik S; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jose S; University College London, London, UK.
Phillips A; University College London, London, UK.
Justice AC; Yale School of Medicine, New Haven, CT, USA; VA Connecticut Healthcare System, West Haven, CT, USA.
Tate JP; Yale School of Medicine, New Haven, CT, USA; VA Connecticut Healthcare System, West Haven, CT, USA.
Gill J; Southern Alberta HIV Clinic, University of Calgary, Calgary, AB, Canada.
Pacheco A; Programa de Computação Científica, FIOCRUZ, Rio de Janeiro, Brazil.
Veloso VG; Programa de Computação Científica, FIOCRUZ, Rio de Janeiro, Brazil.
Bucher HC; Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland.
Egger M; Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; University of Bern, Institute for Social and Preventive Medicine, Bern, Switzerland.
Furrer H; Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland.
Porter K; University College London, London, UK.
Touloumi G; Department of Hygiene, Epidemiology and Medical Statistics, Athens University Medical School, Athens, Greece.
Crane H; Department of Medicine, University of Washington, Seattle, WA, USA.
Miro JM; Infectious Diseases, Hospital Clinic-IDIBAPS, Barcelona, Spain.
Sterne JA; School of Social and Community Medicine, University of Bristol, Bristol, UK.
Costagliola D; Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France.
Saag M; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Hernán MA; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA; Harvard-MIT Division of Health Sciences and Technology, Boston, MA, USA.
Pokaż więcej
Corporate Authors :
HIV-CAUSAL Collaboration
Centers for AIDS Research Network of Integrated Clinical Systems
Źródło :
The lancet. HIV [Lancet HIV] 2017 Jun; Vol. 4 (6), pp. e251-e259. Date of Electronic Publication: 2017 Apr 11.
Typ publikacji :
Comparative Study; Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Monitoring/*methods
HIV Infections/*drug therapy
Adolescent ; Adult ; Anti-HIV Agents/economics ; Anti-HIV Agents/therapeutic use ; CD4 Lymphocyte Count ; Developed Countries ; Drug Monitoring/economics ; Europe ; Female ; HIV Infections/blood ; HIV Infections/economics ; HIV Infections/virology ; HIV-1/drug effects ; HIV-1/genetics ; HIV-1/isolation & purification ; HIV-1/physiology ; Humans ; Male ; Middle Aged ; Prospective Studies ; Viral Load ; Young Adult
Czasopismo naukowe
Tytuł :
Associations between daily air quality and hospitalisations for acute exacerbation of chronic obstructive pulmonary disease in Beijing, 2013-17: an ecological analysis.
Autorzy :
Liang L; Clinical Epidemiology and Tobacco Dependence Treatment Research Department, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Cai Y; MRC-PHE Centre for Environment and Health, Department of Analytical, Environmental and Forensic Sciences, School of Population Health and Environmental Sciences, King's College London, London, UK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Barratt B; MRC-PHE Centre for Environment and Health, Department of Analytical, Environmental and Forensic Sciences, School of Population Health and Environmental Sciences, King's College London, London, UK.
Lyu B; Huayun Sounding (Beijing) Meteorological Technology Co, Beijing, China.
Chan Q; MRC-PHE Centre for Environment and Health, Department of Analytical, Environmental and Forensic Sciences, School of Population Health and Environmental Sciences, King's College London, London, UK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Hansell AL; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK.
Xie W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; Peking University Clinical Research Institute, Peking University Health Science Centre, Beijing, China.
Zhang D; Clinical Epidemiology and Tobacco Dependence Treatment Research Department, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Kelly FJ; MRC-PHE Centre for Environment and Health, Department of Analytical, Environmental and Forensic Sciences, School of Population Health and Environmental Sciences, King's College London, London, UK.
Tong Z; Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. Electronic address: .
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Źródło :
The Lancet. Planetary health [Lancet Planet Health] 2019 Jun; Vol. 3 (6), pp. e270-e279.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Air Pollution/*analysis
Hospitalization/*statistics & numerical data
Pulmonary Disease, Chronic Obstructive/*epidemiology
Adult ; Aged ; Aged, 80 and over ; Air Pollutants/analysis ; Beijing/epidemiology ; Environmental Exposure/analysis ; Environmental Monitoring ; Female ; Humans ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/chemically induced ; Seasons ; Young Adult
Czasopismo naukowe
Tytuł :
Association between pregnancy loss and ambient PM 2·5 using survey data in Africa: a longitudinal case-control study, 1998-2016.
Autorzy :
Xue T; BIC-ESAT and SKL-ESPC, College of Environmental Science and Engineering, Peking University, Beijing, China.
Zhu T; BIC-ESAT and SKL-ESPC, College of Environmental Science and Engineering, Peking University, Beijing, China. Electronic address: .
Geng G; Ministry of Education Key Laboratory for Earth System Modeling, Department of Earth System Science, Tsinghua University, Beijing, China.
Zhang Q; Ministry of Education Key Laboratory for Earth System Modeling, Department of Earth System Science, Tsinghua University, Beijing, China.
Pokaż więcej
Źródło :
The Lancet. Planetary health [Lancet Planet Health] 2019 May; Vol. 3 (5), pp. e219-ee225.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Abortion, Spontaneous/*epidemiology
Air Pollutants/*adverse effects
Maternal Exposure/*adverse effects
Particulate Matter/*adverse effects
Pregnancy Outcome/*epidemiology
Stillbirth/*epidemiology
Adolescent ; Adult ; Africa ; Case-Control Studies ; Environmental Monitoring ; Female ; Humans ; Longitudinal Studies ; Middle Aged ; Pregnancy ; Young Adult
Czasopismo naukowe

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