Temat: "nicotinic acetylcholine receptor" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: PNU-120596, a positive allosteric modulator of α7 nicotinic acetylcholine receptor, directly inhibits p38 MAPK.
Autorzy :: Uwada J; Division of Cellular Signal Transduction, Department of Biochemistry, Asahikawa Medical University, Asahikawa 078-8510, Japan. Electronic address: .
Nakazawa H; Department of Functional Anatomy and Neuroscience, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Mikami D; Department of Nephrology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Islam MS; Division of Cellular Signal Transduction, Department of Biochemistry, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Muramatsu I; Department of Pharmacology, Kanazawa Medical University, Kanazawa 920-0293, Japan.
Taniguchi T; Division of Cellular Signal Transduction, Department of Biochemistry, Asahikawa Medical University, Asahikawa 078-8510, Japan; Department of Urology, Otaki Hospital, Fukui 910-0029, Japan.
Yazawa T; Division of Cellular Signal Transduction, Department of Biochemistry, Asahikawa Medical University, Asahikawa 078-8510, Japan.; Pokaż więcej
Źródło :: Biochemical pharmacology [Biochem Pharmacol] 2020 Dec; Vol. 182, pp. 114297. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Isoxazoles/*pharmacology
Phenylurea Compounds/*pharmacology
Protein Kinase Inhibitors/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*agonists
p38 Mitogen-Activated Protein Kinases/*antagonists & inhibitors
Allosteric Regulation/drug effects ; Allosteric Regulation/physiology ; Animals ; Dose-Response Relationship, Drug ; Humans ; Isoxazoles/chemistry ; MCF-7 Cells ; Mice ; Phenylurea Compounds/chemistry ; Protein Kinase Inhibitors/chemistry ; alpha7 Nicotinic Acetylcholine Receptor/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Activation of α7nACh receptor protects against acute pancreatitis through enhancing TFEB-regulated autophagy.
Autorzy :: Li B; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wu J; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bao J; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Han X; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen S; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ye X; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dai J; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wu Z; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Niu M; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
He Y; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ni J; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wen L; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: .
Wang X; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: .
Hu G; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: .; Pokaż więcej
Źródło :: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Dec 01; Vol. 1866 (12), pp. 165971. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Autophagy*/drug effects
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*metabolism
Pancreatitis/*metabolism
alpha7 Nicotinic Acetylcholine Receptor/*agonists
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Aconitine/administration & dosage ; Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Animals ; Benzamides/administration & dosage ; Benzamides/pharmacology ; Bridged Bicyclo Compounds/administration & dosage ; Bridged Bicyclo Compounds/pharmacology ; Ceruletide/administration & dosage ; Ethanol/administration & dosage ; Fatty Acids, Monounsaturated/administration & dosage ; Injections, Intraperitoneal ; Lipopolysaccharides/administration & dosage ; Male ; Mice ; Mice, Inbred BALB C ; Pancreatitis/chemically induced ; Pancreatitis/drug therapy ; Signal Transduction/drug effects ; alpha7 Nicotinic Acetylcholine Receptor/antagonists & inhibitors
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis.
Autorzy :: Vulfius CA; Laboratory of Cellular Neurobilogy, Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino Moscow region, Russia.
Lebedev DS; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Kryukova EV; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Kudryavtsev DS; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Kolbaev SN; Research Center of Neurology, Moscow, Russia.
Utkin YN; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Tsetlin VI; Department of Molecular Neuroimmune Signaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.; Pokaż więcej
Źródło :: Journal of neurochemistry [J Neurochem] 2020 Nov; Vol. 155 (3), pp. 274-284. Date of Electronic Publication: 2020 Apr 19.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Chloride Channels/*metabolism
Isoxazoles/*pharmacology
Ligand-Gated Ion Channels/*metabolism
Phenylurea Compounds/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*agonists
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Allosteric Regulation/drug effects ; Allosteric Regulation/physiology ; Amino Acid Sequence ; Animals ; Cells, Cultured ; Chloride Channels/antagonists & inhibitors ; Chloride Channels/genetics ; Female ; Humans ; Ligand-Gated Ion Channels/antagonists & inhibitors ; Ligand-Gated Ion Channels/genetics ; Lymnaea ; PC12 Cells ; Rats ; Rats, Wistar ; Xenopus laevis ; alpha7 Nicotinic Acetylcholine Receptor/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation.
Autorzy :: Pismataro MC; Department of Pharmaceutical Sciences, Medicinal Chemistry Section 'Pietro Pratesi', University of Milan, Via L. Mangiagalli 25, 20133, Milan, Italy; Department of Chemistry, University of Florida, P.O. Box 117200, Gainesville, FL 32611-7200, USA; Department of Pharmacology and Therapeutics, University of Florida, P.O. Box 100267, Gainesville, FL 32610-0267, USA.
Horenstein NA; Department of Chemistry, University of Florida, P.O. Box 117200, Gainesville, FL 32611-7200, USA.
Stokes C; Department of Pharmacology and Therapeutics, University of Florida, P.O. Box 100267, Gainesville, FL 32610-0267, USA.
Quadri M; Department of Pharmaceutical Sciences, Medicinal Chemistry Section 'Pietro Pratesi', University of Milan, Via L. Mangiagalli 25, 20133, Milan, Italy; Department of Chemistry, University of Florida, P.O. Box 117200, Gainesville, FL 32611-7200, USA; Department of Pharmacology and Therapeutics, University of Florida, P.O. Box 100267, Gainesville, FL 32610-0267, USA.
De Amici M; Department of Pharmaceutical Sciences, Medicinal Chemistry Section 'Pietro Pratesi', University of Milan, Via L. Mangiagalli 25, 20133, Milan, Italy.
Papke RL; Department of Pharmacology and Therapeutics, University of Florida, P.O. Box 100267, Gainesville, FL 32610-0267, USA.
Dallanoce C; Department of Pharmaceutical Sciences, Medicinal Chemistry Section 'Pietro Pratesi', University of Milan, Via L. Mangiagalli 25, 20133, Milan, Italy. Electronic address: .; Pokaż więcej
Źródło :: European journal of medicinal chemistry [Eur J Med Chem] 2020 Nov 01; Vol. 205, pp. 112669. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :: Journal Article
MeSH Terms :: Drug Design*
Azabicyclo Compounds/*pharmacology
Electrophysiological Phenomena/*drug effects
Furans/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Animals ; Azabicyclo Compounds/chemistry ; Chemistry Techniques, Synthetic ; Furans/chemistry ; Humans ; Hydrogen Bonding ; Ligands ; Structure-Activity Relationship ; Xenopus laevis ; alpha7 Nicotinic Acetylcholine Receptor/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: CDP-choline and galantamine, a personalized α7 nicotinic acetylcholine receptor targeted treatment for the modulation of speech MMN indexed deviance detection in healthy volunteers: a pilot study.
Autorzy :: Choueiry J; Department of Neuroscience, Faculty of Medicine, University of Ottawa, 1145 Carling Ave, Ottawa, ON, K1Z 7K4, Canada. .; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada. .; Department of Psychology, University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada. .
Blais CM; Institute of Cognitive Science, Carleton University, Ottawa, ON, Canada.
Shah D; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada.
Smith D; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.; Department of Psychology, University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada.; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada.
Fisher D; Department of Psychology, Faculty of Social Sciences, Mount Saint Vincent University, Halifax, NS, Canada.
Illivitsky V; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.
Knott V; Department of Neuroscience, Faculty of Medicine, University of Ottawa, 1145 Carling Ave, Ottawa, ON, K1Z 7K4, Canada.; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.; Department of Psychology, University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada.; Institute of Cognitive Science, Carleton University, Ottawa, ON, Canada.; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada.; Pokaż więcej
Źródło :: Psychopharmacology [Psychopharmacology (Berl)] 2020 Dec; Vol. 237 (12), pp. 3665-3687. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :: Journal Article; Randomized Controlled Trial
MeSH Terms :: Auditory Perception/*drug effects
Cytidine Diphosphate Choline/*administration & dosage
Galantamine/*administration & dosage
Speech Perception/*drug effects
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Adult ; Auditory Cortex/drug effects ; Auditory Cortex/physiology ; Auditory Perception/physiology ; Cross-Over Studies ; Double-Blind Method ; Drug Delivery Systems/methods ; Electroencephalography/drug effects ; Electroencephalography/methods ; Evoked Potentials, Auditory/drug effects ; Evoked Potentials, Auditory/physiology ; Female ; Healthy Volunteers ; Humans ; Male ; Nootropic Agents/administration & dosage ; Pilot Projects ; Speech/drug effects ; Speech/physiology ; Speech Perception/physiology ; alpha7 Nicotinic Acetylcholine Receptor/physiology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Allosterically Potentiated α 7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium.
Autorzy :: Miller DR; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.).
Khoshbouei H; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.).
Garai S; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.).
Cantwell LN; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.).
Stokes C; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.).
Thakur G; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.).
Papke RL; Departments of Neuroscience (D.R.M., H.K.) and Pharmacology and Therapeutics (C.S., R.L.P.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., L.N.C., G.T.) .; Pokaż więcej
Źródło :: Molecular pharmacology [Mol Pharmacol] 2020 Dec; Vol. 98 (6), pp. 695-709. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Calcium/*metabolism
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Acetylcholine/metabolism ; Allosteric Regulation/drug effects ; Allosteric Site ; Animals ; Cell Membrane Permeability/drug effects ; HEK293 Cells ; Humans ; Oocytes ; Patch-Clamp Techniques ; Phenylpropionates/pharmacology ; Piperazines/pharmacology ; Quinolines/pharmacology ; Sulfonamides/pharmacology ; Xenopus laevis ; alpha7 Nicotinic Acetylcholine Receptor/agonists
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: Efficient screening of ligand-receptor complex formation using fluorescence labeling and size-exclusion chromatography.
Autorzy :: Kulbatskii DS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
Shulepko MA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow, 117997, Russia.
Sluchanko NN; A. N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, Leninskiy Prospect 33, Building 1, Moscow, 119071, Russia.
Yablokov EO; Federal State Budgetary Institution 'V.N. Orekhovich Research Institute of Biomedical Chemistry', Pogodinskaya 10k8, Moscow, 119121, Russia.
Kamyshinsky RA; National Research Center 'Kurchatov Institute', Academic Kurchatov Sq. 1, Moscow, 123182, Russia; Shubnikov Institute of Crystallography of Federal Scientific Research Centre 'Crystallography and Photonics' of Russian Academy of Sciences, Leninskiy Prospect 59, Moscow, 119333, Russia.
Chesnokov YM; National Research Center 'Kurchatov Institute', Academic Kurchatov Sq. 1, Moscow, 123182, Russia; Shubnikov Institute of Crystallography of Federal Scientific Research Centre 'Crystallography and Photonics' of Russian Academy of Sciences, Leninskiy Prospect 59, Moscow, 119333, Russia.
Kirpichnikov MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow, 117997, Russia; Biological Faculty, Lomonosov Moscow State University, Leninskie gory, 1k12, Moscow, 119192, Russia.
Lyukmanova EN; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow, 117997, Russia; Biological Faculty, Lomonosov Moscow State University, Leninskie gory, 1k12, Moscow, 119192, Russia. Electronic address: .; Pokaż więcej
Źródło :: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Oct 29; Vol. 532 (1), pp. 127-133. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: alpha7 Nicotinic Acetylcholine Receptor/*chemistry
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Animals ; Bungarotoxins/chemistry ; Bungarotoxins/metabolism ; Carrier Proteins/chemistry ; Carrier Proteins/metabolism ; Carrier Proteins/ultrastructure ; Chromatography, Gel ; Cryoelectron Microscopy ; Elapid Venoms/chemistry ; Elapid Venoms/metabolism ; Fluorescent Dyes ; Humans ; Ligands ; Protein Interaction Domains and Motifs ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/metabolism ; Recombinant Fusion Proteins/ultrastructure ; Surface Plasmon Resonance ; alpha7 Nicotinic Acetylcholine Receptor/ultrastructure
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α 7 nAChR.
Autorzy :: Papke RL; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.) .
Garai S; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.).
Stokes C; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.).
Horenstein NA; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.).
Zimmerman AD; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.).
Abboud KA; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.).
Thakur GA; Departments of Pharmacology and Therapeutics (R.L.P., C.S., A.D.Z.) and Chemistry (N.A.H., K.A.A.), University of Florida, Gainesville, Florida; and Department of Pharmaceutical Sciences, School of Pharmacy, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts (S.G., G.A.T.) .; Pokaż więcej
Źródło :: Molecular pharmacology [Mol Pharmacol] 2020 Oct; Vol. 98 (4), pp. 292-302. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Sulfonamides/*chemical synthesis
Sulfonamides/*pharmacology
Xenopus laevis/*genetics
alpha7 Nicotinic Acetylcholine Receptor/*chemistry
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Allosteric Regulation/drug effects ; Animals ; Animals, Genetically Modified ; Binding Sites ; Humans ; Models, Molecular ; Molecular Docking Simulation ; Molecular Structure ; Mutation ; Stereoisomerism ; Sulfonamides/chemistry ; Xenopus laevis/metabolism ; alpha7 Nicotinic Acetylcholine Receptor/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: Neuroprotective Effect of Curcumin on the Nigrostriatal Pathway in a 6-Hydroxydopmine-Induced Rat Model of Parkinson's Disease is Mediated by α7-Nicotinic Receptors.
Autorzy :: El Nebrisi E; Department of Pharmacology, Dubai Medical College, Dubai Medical University, Dubai 20170, UAE.; Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain PO BOX 17666, UAE.
Javed H; Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain PO BOX 17666, UAE.
Ojha SK; Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain PO BOX 17666, UAE.
Oz M; Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain PO BOX 17666, UAE.; Department of Pharmacology and Therapeutics, College of Pharmacy, Kuwait University, Kuwait 24923, Kuwait.
Shehab S; Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain PO BOX 17666, UAE.; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 03; Vol. 21 (19). Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :: Journal Article
MeSH Terms :: Curcumin/*pharmacology
Parkinson Disease/*drug therapy
Parkinson Disease, Secondary/*drug therapy
alpha7 Nicotinic Acetylcholine Receptor/*genetics
Animals ; Corpus Striatum/drug effects ; Corpus Striatum/metabolism ; Corpus Striatum/pathology ; Disease Models, Animal ; Dopamine/metabolism ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/pathology ; Humans ; Oxidopamine/toxicity ; Parkinson Disease/genetics ; Parkinson Disease/pathology ; Parkinson Disease, Secondary/chemically induced ; Parkinson Disease, Secondary/genetics ; Parkinson Disease, Secondary/pathology ; Rats ; Substantia Nigra/drug effects ; Substantia Nigra/pathology ; alpha7 Nicotinic Acetylcholine Receptor/administration & dosage
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 10 10.

Tytuł :: Regulation of the deleterious effects of binge-like exposure to alcohol during adolescence by α7 nicotinic acetylcholine receptor agents: prevention by pretreatment with a α7 negative allosteric modulator and emulation by a α7 agonist in alcohol-preferring (P) male and female rats.
Autorzy :: Rodd ZA; Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Neuroscience Research Building, 320 W. 15th Street, Suite 300B, Indianapolis, IN, 46202-2266, USA. .; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. .
Hauser SR; Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Neuroscience Research Building, 320 W. 15th Street, Suite 300B, Indianapolis, IN, 46202-2266, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Swartzwelder HS; Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Neuroscience Research Building, 320 W. 15th Street, Suite 300B, Indianapolis, IN, 46202-2266, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Waeiss RA; Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Neuroscience Research Building, 320 W. 15th Street, Suite 300B, Indianapolis, IN, 46202-2266, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Lahiri DK; Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Neuroscience Research Building, 320 W. 15th Street, Suite 300B, Indianapolis, IN, 46202-2266, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Bell RL; Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Neuroscience Research Building, 320 W. 15th Street, Suite 300B, Indianapolis, IN, 46202-2266, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.; Pokaż więcej
Źródło :: Psychopharmacology [Psychopharmacology (Berl)] 2020 Sep; Vol. 237 (9), pp. 2601-2611. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :: Journal Article
MeSH Terms :: Binge Drinking/*drug therapy
Bridged-Ring Compounds/*therapeutic use
Ethanol/*adverse effects
Spiro Compounds/*therapeutic use
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Age Factors ; Allosteric Regulation/drug effects ; Allosteric Regulation/physiology ; Animals ; Behavior, Addictive/drug therapy ; Behavior, Addictive/genetics ; Behavior, Addictive/psychology ; Binge Drinking/genetics ; Binge Drinking/psychology ; Bridged-Ring Compounds/pharmacology ; Ethanol/administration & dosage ; Female ; Male ; Rats ; Rats, Transgenic ; Spiro Compounds/pharmacology ; Treatment Outcome ; alpha7 Nicotinic Acetylcholine Receptor/physiology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: In Silico Finding of Key Interaction Mediated α3β4 and α7 Nicotinic Acetylcholine Receptor Ligand Selectivity of Quinuclidine-Triazole Chemotype.
Autorzy :: Arunrungvichian K; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand.
Chongruchiroj S; Department of Microbiology, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand.
Sarasamkan J; Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Khon Kaen University, 123 Mittraparp Highway, Khon Kaen 4002, Thailand.
Schüürmann G; UFZ Department of Ecological Chemistry, Helmholtz Centre for Environmental Research, Permoserstrasse 15, 04318 Leipzig, Germany.; Institute of Organic Chemistry, Technical University Bergakademie Freiberg, Leipziger Strasse 29, 09596 Freiberg, Germany.
Brust P; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstrasse 15, 04318 Leipzig, Germany.
Vajragupta O; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand.; Office of Research Affairs, Faculty of Pharmaceutical Sciences, Chulalongkorn University, 254 Phayathai Road, Bangkok 10330, Thailand.; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 27; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :: Journal Article
MeSH Terms :: Quinuclidines/*pharmacology
Receptors, Nicotinic/*metabolism
Triazoles/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Amino Acid Motifs ; Binding Sites ; Computer Simulation ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Protein Conformation ; Quinuclidines/chemistry ; Receptors, Nicotinic/chemistry ; Triazoles/chemistry ; alpha7 Nicotinic Acetylcholine Receptor/chemistry
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 12 12.

Tytuł :: Functional characterization of multifunctional ligands targeting acetylcholinesterase and alpha 7 nicotinic acetylcholine receptor.
Autorzy :: Cieslikiewicz-Bouet M; Normandie Univ, UNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), 76000 Rouen, France.
Naldi M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy.
Bartolini M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy.
Pérez B; Departament de Farmacologia, de Terapèutica i de Toxicologia Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain.
Servent D; Université Paris Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SIMoS, 91191 Gif-sur-Yvette, France; CNRS, ERL 9004, 91191 Gif sur Yvette, France.
Jean L; Normandie Univ, UNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), 76000 Rouen, France. Electronic address: .
Aráoz R; Université Paris Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SIMoS, 91191 Gif-sur-Yvette, France; CNRS, ERL 9004, 91191 Gif sur Yvette, France. Electronic address: .
Renard PY; Normandie Univ, UNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), 76000 Rouen, France. Electronic address: .; Pokaż więcej
Źródło :: Biochemical pharmacology [Biochem Pharmacol] 2020 Jul; Vol. 177, pp. 114010. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Cholinesterase Inhibitors/*chemistry
Cholinesterase Inhibitors/*pharmacology
alpha7 Nicotinic Acetylcholine Receptor/*antagonists & inhibitors
Acetylcholinesterase ; Alkynes/chemistry ; Alzheimer Disease/drug therapy ; Animals ; Blood-Brain Barrier/drug effects ; Butyrylcholinesterase/metabolism ; Catalysis ; Cholinesterase Inhibitors/chemical synthesis ; Click Chemistry ; Copper ; Cycloaddition Reaction ; Dose-Response Relationship, Drug ; Drug Design ; Drug Evaluation, Preclinical ; Female ; Humans ; Ligands ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Tacrine/chemistry ; Tacrine/pharmacology ; Xenopus laevis ; alpha7 Nicotinic Acetylcholine Receptor/agonists ; alpha7 Nicotinic Acetylcholine Receptor/genetics ; alpha7 Nicotinic Acetylcholine Receptor/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Structure-Based Discovery of Dual-Target Hits for Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptors: In Silico Studies and In Vitro Confirmation.
Autorzy :: Oddsson S; Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, 107 Reykjavík, Iceland.; Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.; Brain and Mind Centre, The University of Sydney, Camperdown, NSW 2050, Australia.
Kowal NM; Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, 107 Reykjavík, Iceland.; Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.; Brain and Mind Centre, The University of Sydney, Camperdown, NSW 2050, Australia.
Ahring PK; Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.; Brain and Mind Centre, The University of Sydney, Camperdown, NSW 2050, Australia.
Olafsdottir ES; Faculty of Pharmaceutical Sciences, School of Health Sciences, University of Iceland, 107 Reykjavík, Iceland.
Balle T; Sydney School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.; Brain and Mind Centre, The University of Sydney, Camperdown, NSW 2050, Australia.; Pokaż więcej
Źródło :: Molecules (Basel, Switzerland) [Molecules] 2020 Jun 22; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :: Journal Article
MeSH Terms :: Acetylcholinesterase/*drug effects
Alzheimer Disease/*drug therapy
Cholinesterase Inhibitors/*isolation & purification
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Acetylcholinesterase/chemistry ; Acetylcholinesterase/ultrastructure ; Alzheimer Disease/enzymology ; Alzheimer Disease/pathology ; Cholinesterase Inhibitors/chemistry ; Computer Simulation ; Drug Evaluation, Preclinical/methods ; Humans ; Ligands ; Molecular Docking Simulation ; Molecular Targeted Therapy ; Protein Conformation/drug effects ; Structure-Activity Relationship ; User-Computer Interface ; alpha7 Nicotinic Acetylcholine Receptor/chemistry ; alpha7 Nicotinic Acetylcholine Receptor/ultrastructure
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 14 14.

Tytuł :: Lemairamin, isolated from the Zanthoxylum plants, alleviates pain hypersensitivity via spinal α7 nicotinic acetylcholine receptors.
Autorzy :: Wang ZY; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Han QQ; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Deng MY; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhao MJ; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Apryani E; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Shoaib RM; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Wei DQ; School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Wang YX; King's Lab, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address: .; Pokaż więcej
Źródło :: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 May 14; Vol. 525 (4), pp. 1087-1094. Date of Electronic Publication: 2020 Mar 14.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Acrylamides/*pharmacology
Analgesics/*pharmacology
Cancer Pain/*drug therapy
Hyperalgesia/*drug therapy
Microglia/*drug effects
Neuralgia/*drug therapy
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Acrylamides/administration & dosage ; Acrylamides/therapeutic use ; Analgesics/administration & dosage ; Analgesics/therapeutic use ; Animals ; Female ; Formaldehyde ; Hyperalgesia/genetics ; Hyperalgesia/metabolism ; Injections, Spinal ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Male ; Mice ; Microglia/metabolism ; Minocycline/administration & dosage ; Naloxone/administration & dosage ; Rats ; Rats, Wistar ; Spinal Cord/metabolism ; Zanthoxylum/chemistry ; Zanthoxylum/metabolism ; alpha7 Nicotinic Acetylcholine Receptor/genetics ; alpha7 Nicotinic Acetylcholine Receptor/metabolism ; beta-Endorphin/genetics ; beta-Endorphin/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: CHRFAM7A reduces monocyte/macrophage migration and colony formation in vitro.
Autorzy :: Chan TW; Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 W. Arbor Drive #8896, San Diego, CA, 92103, USA.
Langness S; Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 W. Arbor Drive #8896, San Diego, CA, 92103, USA.
Cohen O; Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 W. Arbor Drive #8896, San Diego, CA, 92103, USA.
Eliceiri BP; Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 W. Arbor Drive #8896, San Diego, CA, 92103, USA.
Baird A; Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 W. Arbor Drive #8896, San Diego, CA, 92103, USA.
Costantini TW; Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery, University of California San Diego School of Medicine, 200 W. Arbor Drive #8896, San Diego, CA, 92103, USA. .; Pokaż więcej
Źródło :: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2020 Jul; Vol. 69 (7), pp. 631-633. Date of Electronic Publication: 2020 Apr 17.
Typ publikacji :: Journal Article
MeSH Terms :: alpha7 Nicotinic Acetylcholine Receptor/*antagonists & inhibitors
Animals ; Cell Adhesion/physiology ; Cell Movement/genetics ; Cell Movement/physiology ; Cell Proliferation/physiology ; Gene Expression ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Leukocytes ; Macrophages/physiology ; Mice ; Monocytes/physiology ; RAW 264.7 Cells ; Stem Cells/physiology ; THP-1 Cells ; Transduction, Genetic ; alpha7 Nicotinic Acetylcholine Receptor/genetics ; alpha7 Nicotinic Acetylcholine Receptor/physiology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors.
Autorzy :: Mohan MK; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka 560012, India.
Abraham N; Institute for Molecular Bioscience, Queensland Bioscience Precinct, The University of Queensland, 306 Carmody Rd., St. Lucia Queensland 4072, Australia.
R P R; Sathyabama Institute of Science and Technology, Jeppiaar Nagar, Rajiv Gandhi Salai, Chennai 600119, Tamil Nadu, India.
Jayaseelan BF; Bombay Natural History Society, Hornbill House, Dr. Salim Ali Chowk, Mumbai 400 001, Maharashtra, India.
Ragnarsson L; Institute for Molecular Bioscience, Queensland Bioscience Precinct, The University of Queensland, 306 Carmody Rd., St. Lucia Queensland 4072, Australia.
Lewis RJ; Institute for Molecular Bioscience, Queensland Bioscience Precinct, The University of Queensland, 306 Carmody Rd., St. Lucia Queensland 4072, Australia .
Sarma SP; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, Karnataka 560012, India .; Pokaż więcej
Źródło :: The Journal of biological chemistry [J Biol Chem] 2020 May 15; Vol. 295 (20), pp. 7096-7112. Date of Electronic Publication: 2020 Mar 31.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Neurotoxins*/pharmacology
Peptides*/chemistry
Peptides*/pharmacology
Receptors, Nicotinic*/chemistry
Receptors, Nicotinic*/metabolism
alpha7 Nicotinic Acetylcholine Receptor*/chemistry
alpha7 Nicotinic Acetylcholine Receptor*/metabolism
Conus Snail/*chemistry
Disulfides/*chemistry
Allosteric Regulation ; Animals ; COS Cells ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Nicotinic Receptor Subunit Distribution in Auditory Cortex: Impact of Aging on Receptor Number and Function.
Autorzy :: Ghimire M; Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois 62702.
Cai R; Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois 62702.
Ling L; Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois 62702.
Hackett TA; Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Caspary DM; Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois 62702 .; Pokaż więcej
Źródło :: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jul 22; Vol. 40 (30), pp. 5724-5739. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Aging/*metabolism
Auditory Cortex/*metabolism
Receptors, Nicotinic/*metabolism
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Animals ; Auditory Cortex/chemistry ; Male ; Protein Subunits/analysis ; Protein Subunits/metabolism ; Rats ; Rats, Inbred BN ; Rats, Long-Evans ; Rats, Transgenic ; Receptors, Nicotinic/analysis ; alpha7 Nicotinic Acetylcholine Receptor/analysis
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse.
Autorzy :: Gausserès B; Biology and Pathology of the Endocrine Pancreas, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Liu J; Biology and Pathology of the Endocrine Pancreas, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Foppen E; Regulation of Glycemia by Central Nervous System, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Tourrel-Cuzin C; Biology and Pathology of the Endocrine Pancreas, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Rodriguez Sanchez-Archidona A; Center for Integrative Genomics, University of Lausanne, CH-1015 Lausanne, Switzerland.
Delangre E; Biology and Pathology of the Endocrine Pancreas, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Cruciani-Guglielmacci C; Regulation of Glycemia by Central Nervous System, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Pons S; Institut Pasteur, UMR 3571, CNRS, Department of Neuroscience, Integrative Neurobiology of Cholinergic Systems, CEDEX 15, 75724 Paris, France.
Maskos U; Institut Pasteur, UMR 3571, CNRS, Department of Neuroscience, Integrative Neurobiology of Cholinergic Systems, CEDEX 15, 75724 Paris, France.
Thorens B; Center for Integrative Genomics, University of Lausanne, CH-1015 Lausanne, Switzerland.
Magnan C; Regulation of Glycemia by Central Nervous System, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Movassat J; Biology and Pathology of the Endocrine Pancreas, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.
Maouche K; Biology and Pathology of the Endocrine Pancreas, Université de Paris, BFA, UMR 8251, CNRS, F-75013 Paris, France.; Pokaż więcej
Źródło :: Biomolecules [Biomolecules] 2020 Jul 16; Vol. 10 (7). Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Insulin Resistance*
Glucose Intolerance/*genetics
Hyperglycemia/*genetics
alpha7 Nicotinic Acetylcholine Receptor/*genetics
Animals ; Cell Line ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Female ; Gene Deletion ; Glucose/metabolism ; Glucose Intolerance/metabolism ; Hyperglycemia/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Rats ; alpha7 Nicotinic Acetylcholine Receptor/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 19 19.

Tytuł :: Profile of the Nicotinic Cholinergic Receptor Alpha 7 Subunit Gene Expression is Associated with Response to Varenicline Treatment.
Autorzy :: Santos JR; Laboratory of Genetics and Molecular Cardiology, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Tomaz PRX; Laboratory of Genetics and Molecular Cardiology, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Scholz JR; Smoking Cessation Program Department, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Gaya PV; Smoking Cessation Program Department, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Abe TO; Smoking Cessation Program Department, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Krieger JE; Laboratory of Genetics and Molecular Cardiology, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Pereira AC; Laboratory of Genetics and Molecular Cardiology, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-904, Brazil.
Santos PCJL; Department of Pharmacology-Escola Paulista de Medicina, Universidade Federal de Sao Paulo, EPM-Unifesp, Sao Paulo 04044-020, Brazil.; Pokaż więcej
Źródło :: Genes [Genes (Basel)] 2020 Jul 06; Vol. 11 (7). Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :: Clinical Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Drug Resistance*
Smoking Cessation Agents/*therapeutic use
Varenicline/*therapeutic use
alpha7 Nicotinic Acetylcholine Receptor/*genetics
Aged ; Biomarkers/metabolism ; Female ; Humans ; Male ; Middle Aged ; Smoking Cessation ; alpha7 Nicotinic Acetylcholine Receptor/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task.
Autorzy :: Phenis D; Department of Psychology, The Ohio State University, Columbus, OH, USA.; Department of Neuroscience, The Ohio State University, Columbus, OH, USA.
Vunck SA; Department of Psychology, The Ohio State University, Columbus, OH, USA.
Valentini V; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Arias H; Department of Pharmacology and Physiology, College of Osteopathic Medicine, Oklahoma State University Center for Health Sciences, Tahlequah, OK, USA.
Schwarcz R; Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Bruno JP; Department of Psychology, The Ohio State University, Columbus, OH, USA. .; Department of Neuroscience, The Ohio State University, Columbus, OH, USA. .; Pokaż więcej
Źródło :: Psychopharmacology [Psychopharmacology (Berl)] 2020 Jun; Vol. 237 (6), pp. 1723-1735. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :: Journal Article
MeSH Terms :: Brain/*metabolism
Memory, Short-Term/*physiology
Psychomotor Performance/*physiology
Receptors, N-Methyl-D-Aspartate/*metabolism
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Analgesics/pharmacology ; Animals ; Brain/drug effects ; Kynurenic Acid/pharmacology ; Kynurenine/pharmacology ; Male ; Memory, Short-Term/drug effects ; Nicotine/pharmacology ; Psychomotor Performance/drug effects ; Rats ; Rats, Wistar ; Receptors, N-Methyl-D-Aspartate/agonists ; alpha7 Nicotinic Acetylcholine Receptor/agonists
: Czasopismo naukowe

Szczegóły

Informacja

Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""nicotinic acetylcholine receptor"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język