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Wyświetlanie 1-20 z 11453
Tytuł:
Use of physiologically-based pharmacokinetic modeling to understand the effect of omeprazole administration on the pharmacokinetics of oral extended-release nifedipine.
Autorzy:
Tan ML; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Gao Z; Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, St. Louis, Missouri, USA.
Babiskin A; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Kim MJ; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Fang L; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Zhang L; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Zhao L; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Feb; Vol. 13 (2), pp. 247-256. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Nifedipine*/chemistry
Nifedipine*/pharmacokinetics
Omeprazole*/pharmacology
Humans ; Cytochrome P-450 CYP3A/metabolism ; Drug Interactions ; Drug Liberation ; Administration, Oral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ipomoea carnea mitigates ethanol-induced ulcers in irradiated rats via Nrf2/HO pathway: an in vivo and in silico study.
Autorzy:
Ghareeb, Mosad A. (AUTHOR)
Mohammed, Hala Sh. (AUTHOR)
Aboushousha, Tarek (AUTHOR)
Lotfy, Dina M. (AUTHOR)
El-Shazly, Maha A. M. (AUTHOR)
Sobeh, Mansour (AUTHOR)
Taha, Eman F. S. (AUTHOR)
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Źródło:
Scientific Reports. 2/12/2024, Vol. 14 Issue 1, p1-24. 24p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Photosynthetic Efficiency in Green Bean Plants through the Application of Omeprazole and Melatonin at Low Doses.
Autorzy:
Ramírez-Estrada, Carlos Abel
Sánchez, Esteban
Flores-Córdova, María Antonia
Pérez-Álvarez, Sandra
Noperi-Mosqueda, Linda Citlalli
Chávez-Mendoza, Celia
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Źródło:
International Journal of Plant Biology. Dec2023, Vol. 14 Issue 4, p864-878. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Suspect screening analysis to improve untargeted and targeted UHPLC-qToF approaches: the biodegradability of a proton pump inhibitor medicine and a natural medical device.
Autorzy:
Mattoli L; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Proietti G; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Fodaroni G; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Quintiero CM; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Burico M; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Gianni M; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Giovagnoni E; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Mercati V; Metabolomics and Analytical Sciences, Aboca SpA, Sansepolcro, AR, Italy.
Santi C; Group of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06123, Perugia, Italy. .; Centro di Eccellenza Materiali Innovativi Nanostrutturati (CEMIN), University of Perugia, Via Elce di Sotto 8, 06123, Perugia, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 02; Vol. 14 (1), pp. 51. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Proton Pump Inhibitors*
Gastroesophageal Reflux*
Humans ; Chromatography, High Pressure Liquid/methods ; Omeprazole ; Personality
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cytoprotective Activity of Newly Synthesized 3-(Arylmethylamino)-6-Methyl-4-Phenylpyridin-2(1 H )-Ones Derivatives.
Autorzy:
Sergazy S; RSE 'National Center for Biotechnology', 13/5 Kurgalzhynskoe Road, Nur-Sultan 010000, Kazakhstan.; National Laboratory Astana, Nazarbayev University, 53 Kabanbay Batyr Ave., Nur-Sultan 010000, Kazakhstan.
Shulgau Z; RSE 'National Center for Biotechnology', 13/5 Kurgalzhynskoe Road, Nur-Sultan 010000, Kazakhstan.
Zhulikeyeva A; RSE 'National Center for Biotechnology', 13/5 Kurgalzhynskoe Road, Nur-Sultan 010000, Kazakhstan.
Ramankulov Y; RSE 'National Center for Biotechnology', 13/5 Kurgalzhynskoe Road, Nur-Sultan 010000, Kazakhstan.
Palamarchuk IV; Institute of Chemistry, Tyumen State University, 15a Perekopskaya St., 625003 Tyumen, Russia.
Kulakov IV; RSE 'National Center for Biotechnology', 13/5 Kurgalzhynskoe Road, Nur-Sultan 010000, Kazakhstan.; Institute of Chemistry, Tyumen State University, 15a Perekopskaya St., 625003 Tyumen, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Aug 23; Vol. 27 (17). Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Omeprazole*/pharmacology
Cell Survival ; Molecular Docking Simulation ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of the relationship between polymorphisms in CYP2C19 and the single-dose pharmacokinetics of omeprazole in healthy Chinese volunteers: A multicenter study.
Autorzy:
Zhou S; Department of Pharmacy, Peking University First Hospital, Beijing, China.; Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical Science, Peking University, Beijing, China.
Xie R; Department of Pharmacy, Peking University First Hospital, Beijing, China.
Zhang X; Department of Pharmacy, Peking University First Hospital, Beijing, China.
He X; Department of Pharmacy, Peking University First Hospital, Beijing, China.; Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical Science, Peking University, Beijing, China.
Huang J; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jungang Y; GCP Center, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Liao M; Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Ding Y; The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Yang D; Center of Clinical Pharmacology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Liu Y; The Office of Drug Clinical Trial Institution, Wuhan Jinyintan Hospitial, Wuhan, China.
Zhang Q; Department of Pharmacy, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yang G; Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Liu F; GCP Center, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Guan S; Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
He Q; The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Lou H; Center of Clinical Pharmacology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Gong F; The Office of Drug Clinical Trial Institution, Wuhan Jinyintan Hospitial, Wuhan, China.
Meng X; Department of Pharmacy, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Xiang Q; Department of Pharmacy, Peking University First Hospital, Beijing, China.
Zhao X; Department of Pharmacy, Peking University First Hospital, Beijing, China.
Cui Y; Department of Pharmacy, Peking University First Hospital, Beijing, China.; Institute of Clinical Pharmacology, Peking University, Beijing, China.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2022 Jun; Vol. 15 (6), pp. 1439-1448. Date of Electronic Publication: 2022 Mar 25.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Ulcer Agents*/pharmacokinetics
Cytochrome P-450 CYP2C19*/genetics
Cytochrome P-450 CYP2C19*/metabolism
Omeprazole*/pharmacokinetics
Area Under Curve ; China ; Genotype ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of elagolix on the pharmacokinetics of omeprazole and its metabolites in healthy premenopausal women.
Autorzy:
Nader A; Clinical Pharmacology and Pharmacometrics, AbbVie Inc., North Chicago, Illinois, USA.
Mostafa NM; Clinical Pharmacology and Pharmacometrics, AbbVie Inc., North Chicago, Illinois, USA.
Kim E; Regulated Bioanalysis, AbbVie Inc., North Chicago, Illinois, USA.
Shebley M; Clinical Pharmacology and Pharmacometrics, AbbVie Inc., North Chicago, Illinois, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2022 May; Vol. 15 (5), pp. 1269-1280. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryl Hydrocarbon Hydroxylases*/genetics
Aryl Hydrocarbon Hydroxylases*/metabolism
Hydrocarbons, Fluorinated*/pharmacology
Omeprazole*/pharmacokinetics
Omeprazole*/pharmacology
Pyrimidines*/pharmacology
Adult ; Cytochrome P-450 CYP2C19/genetics ; Cytochrome P-450 CYP2C19/metabolism ; Drug Interactions ; Female ; Genotype ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of nivasorexant (ACT‐539313), a selective orexin‐1‐receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in healthy subjects.
Autorzy:
Berger, Benjamin (AUTHOR)
Kaufmann, Priska (AUTHOR)
Berse, Matthias (AUTHOR)
Treiber, Alexander (AUTHOR)
Grignaschi, Nathalie (AUTHOR)
Dingemanse, Jasper (AUTHOR)
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Źródło:
Pharmacology Research & Perspectives. Oct2023, Vol. 11 Issue 5, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prebiotic prevents the development of gastrointestinal motility disorders caused by omeprazole.
Autorzy:
Korinchak, L. M.
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Alternatywny tytuł:
ПРОБІОТИК ПОПЕРЕДЖУЄ РОЗВИТОК ПОРУШЕНЬ МОТОРИКИ ШЛУНКОВО- КИШКОВОГО ТРАКТУ, ВИКЛИКАНИХ ОМЕПРАЗОЛОМ
Źródło:
Physiological Journal / Fiziologichnyi Zhurnal. 2023, Vol. 68 Issue 5, p83-88. 6p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Predicting delayed methotrexate elimination in pediatric acute lymphoblastic leukemia patients: an innovative web-based machine learning tool developed through a multicenter, retrospective analysis.
Autorzy:
Jian, Chang (AUTHOR)
Chen, Siqi (AUTHOR)
Wang, Zhuangcheng (AUTHOR)
Zhou, Yang (AUTHOR)
Zhang, Yang (AUTHOR)
Li, Ziyu (AUTHOR)
Jian, Jie (AUTHOR)
Wang, Tingting (AUTHOR)
Xiang, Tianyu (AUTHOR)
Wang, Xiao (AUTHOR)
Jia, Yuntao (AUTHOR)
Wang, Huilai (AUTHOR)
Gong, Jun (AUTHOR)
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Źródło:
BMC Medical Informatics & Decision Making. 8/3/2023, Vol. 23 Issue 1, p1-12. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potential Effects of Ibuprofen, Remdesivir and Omeprazole on Dexamethasone Metabolism in Control Sprague Dawley Male Rat Liver Microsomes (Drugs Often Used Together Alongside COVID-19 Treatment).
Autorzy:
Hussain A; School of Life Sciences, Pharmacy and Chemistry, Kingston University, Kingston-upon-Thames, London KT1 2EE, UK.
Naughton DP; School of Life Sciences, Pharmacy and Chemistry, Kingston University, Kingston-upon-Thames, London KT1 2EE, UK.
Barker J; School of Life Sciences, Pharmacy and Chemistry, Kingston University, Kingston-upon-Thames, London KT1 2EE, UK.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Mar 30; Vol. 27 (7). Date of Electronic Publication: 2022 Mar 30.
Typ publikacji:
Journal Article
MeSH Terms:
Dexamethasone*/metabolism
Dexamethasone*/pharmacology
Ibuprofen*/pharmacology
Microsomes, Liver*/metabolism
Omeprazole*/pharmacology
Adenosine Monophosphate/analogs & derivatives ; Alanine/analogs & derivatives ; Animals ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P-450 Enzyme Inhibitors/pharmacology ; Cytochrome P-450 Enzyme System/metabolism ; Isoenzymes/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; COVID-19 Drug Treatment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel.
Autorzy:
Ramste M; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Ritvos M; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Häyrynen S; Veracell Oy, Tampere, Finland.
Kiiski JI; Department of Clinical Pharmacology and Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Niemi M; Department of Clinical Pharmacology and Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.
Sinisalo J; Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2023 Oct; Vol. 16 (10), pp. 2010-2020. Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Platelet Aggregation Inhibitors*/adverse effects
Stroke*
Humans ; Clopidogrel/adverse effects ; Alleles ; Esomeprazole/adverse effects ; Omeprazole/adverse effects ; Cytochrome P-450 CYP2C19/genetics ; Prospective Studies ; Genotype ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evolution of the consumption trend of proton pump inhibitors in the Lleida Health Region between 2002 and 2015.
Autorzy:
Torres-Bondia F; Pharmacy Department, Clinical Neuroscience Research, IRB Lleida, Arnau de Vilanova University Hospital, Lleida, Spain.
de Batlle J; Biomedical Research Networking Centre for Respiratory Diseases (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, CIBERES), Madrid, Spain.; Translational Research Group in Respiratory Medicine, Arnau de Vilanova University Hospital and Santa Maria University Hospital, IRB Lleida, Lleida, Spain.
Galván L; Pharmacy Department, Servei Català de La Salut (Catalan Health Services), Lleida, Spain.
Buti M; Unitat d'Avaluació Clínica (Clinical Evaluation Unit), Institut Català de La Salut (Catalan Institute of Health), Lleida, Spain.
Barbé F; Biomedical Research Networking Centre for Respiratory Diseases (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, CIBERES), Madrid, Spain.; Translational Research Group in Respiratory Medicine, Arnau de Vilanova University Hospital and Santa Maria University Hospital, IRB Lleida, Lleida, Spain.
Piñol-Ripoll G; Unitat Trastorns Cognitius (Cognitive Disorders Unit), Clinical Neuroscience Research, IRB Lleida, Santa Maria University Hospital, Rovira Roure nº 44, 25198, Lleida, Spain. gerard_.
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Źródło:
BMC public health [BMC Public Health] 2022 Apr 24; Vol. 22 (1), pp. 818. Date of Electronic Publication: 2022 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Omeprazole*
Proton Pump Inhibitors*/therapeutic use
Aged ; Esomeprazole ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Spectrophotometric Determination of Aspirin and Omeprazole in the Presence of Salicylic Acid as a Degradation Product: A Comparative Evaluation of Different Univariate/Multivariate Post Processing Algorithms.
Autorzy:
Elmasry MS; Zagazig University, Faculty of Pharmacy, Analytical Chemistry Department, Zagazig 44519, Egypt.
Serag A; Al-Azhar University, Faculty of Pharmacy, Pharmaceutical Analytical Chemistry Department, Nasr City, Cairo 11751, Egypt.
Hassan WS; Zagazig University, Faculty of Pharmacy, Analytical Chemistry Department, Zagazig 44519, Egypt.
El-Mammli MY; Zagazig University, Faculty of Pharmacy, Analytical Chemistry Department, Zagazig 44519, Egypt.
Badrawy M; Egyptian Russian University, Faculty of Pharmacy, Pharmaceutical Chemistry Department, Badr City, 11829, Egypt.
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Źródło:
Journal of AOAC International [J AOAC Int] 2022 Feb 04; Vol. 105 (1), pp. 309-316.
Typ publikacji:
Journal Article
MeSH Terms:
Omeprazole*
Salicylic Acid*
Algorithms ; Aspirin ; Calibration ; Humans ; Least-Squares Analysis ; Spectrophotometry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 11453

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