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Wyszukujesz frazę ""oncogenes"" wg kryterium: Temat


Tytuł :
Role of Oncogenes and Tumor-suppressor Genes in Carcinogenesis: A Review.
Autorzy :
Kontomanolis EN; Department of Obstetrics and Gynecology, Democritus University of Thrace, Alexandroupolis, Greece.
Koutras A; First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Syllaios A; First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Schizas D; First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Mastoraki A; First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Garmpis N; First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece .
Diakosavvas M; First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Angelou K; First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Tsatsaris G; Department of Obstetrics and Gynecology, Democritus University of Thrace, Alexandroupolis, Greece.
Pagkalos A; Department of Obstetrics and Gynecology, General Hospital of Xanthi, Xanthi, Greece.
Ntounis T; First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Fasoulakis Z; First Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, National and Kapodistrian University of Athens, Athens, Greece.
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Źródło :
Anticancer research [Anticancer Res] 2020 Nov; Vol. 40 (11), pp. 6009-6015.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genes, Tumor Suppressor*
Oncogenes*
Carcinogenesis/*genetics
Apoptosis/genetics ; Humans ; Neoplasms/blood supply ; Neoplasms/genetics ; Neovascularization, Pathologic/genetics
Czasopismo naukowe
Tytuł :
Lung cancer pathogenesis and poor response to therapy were dependent on driver oncogenic mutations.
Autorzy :
Sun X; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China. Electronic address: .
Li K; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China.
Zhao R; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China.
Sun Y; Department of Anesthesiology and Operation, Operating Centre, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China.
Xu J; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China; Department of General Surgery, the People's Hospital of Shanyang County, Luonan City, Shaanxi Province 726411, China.
Peng ZY; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China.
Song RD; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China.
Ren H; Department of Thoracic Surgery, the Second Department of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Cancer Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an City, Shaanxi Province 710061, China.
Tang SC; University of Mississippi Medical Center, Cancer Center and Research Institute, 2500 North State Street, Jackson, MS 39216, USA. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118797. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung/*genetics
Carcinogenesis/*genetics
Lung Neoplasms/*genetics
Mutation/*genetics
Oncogenes/*genetics
Smoking/*genetics
Adenocarcinoma of Lung/pathology ; Adenocarcinoma of Lung/therapy ; Aged ; Biomarkers, Tumor/genetics ; Carcinogenesis/drug effects ; Carcinogenesis/pathology ; Female ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/therapy ; Male ; Middle Aged ; Mutation/drug effects ; Oncogenes/drug effects ; Smoking/pathology ; Smoking/therapy ; Survival Rate/trends ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Broad genic repression domains signify enhanced silencing of oncogenes.
Autorzy :
Zhao D; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA.; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Zhang L; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA. .; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA. .; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA. .
Zhang M; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Xia B; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA.; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Lv J; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA.; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Gao X; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA.; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Wang G; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA.; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Meng Q; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Yi Y; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Zhu S; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA.; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Tomoiaga AS; Business Analytics, CIS & Law Department, The O'Malley School of Business Accounting, Manhattan College, Riverdale, NY, USA.
Lee MG; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cooke JP; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA.; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA.; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA.
Cao Q; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. .; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. .
Chen K; Center for Bioinformatics and Computational Biology, Houston Methodist Research Institute, Houston, TX, USA. .; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA. .; Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, NY, USA. .; Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 03; Vol. 11 (1), pp. 5560. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Silencing*
Oncogenes*
Chromatin/*genetics
Breast Neoplasms/genetics ; CD4-Positive T-Lymphocytes/metabolism ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Conserved Sequence/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Histones/metabolism ; Humans ; Lysine/metabolism ; Methylation ; Nucleotide Motifs/genetics ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Regulatory Sequences, Nucleic Acid/genetics ; Transcription Elongation, Genetic ; Transcription Initiation, Genetic
Czasopismo naukowe
Tytuł :
MicroRNA-493-5p-mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion.
Autorzy :
Yasukawa K; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.; Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
Liew LC; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.; Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Disease Modeling and Therapeutics Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore City, Singapore.
Hagiwara K; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.
Hironaka-Mitsuhashi A; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.
Qin XY; Liver Cancer Prevention Research Unit, RIKEN Cluster for Pioneering Research, Wako, Japan.
Furutani Y; Liver Cancer Prevention Research Unit, RIKEN Cluster for Pioneering Research, Wako, Japan.
Tanaka Y; Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Nakagama H; Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; National Cancer Center, Tokyo, Japan.
Kojima S; Liver Cancer Prevention Research Unit, RIKEN Cluster for Pioneering Research, Wako, Japan.
Kato T; Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
Ochiya T; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.
Gailhouste L; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.
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Źródło :
Cancer science [Cancer Sci] 2020 Mar; Vol. 111 (3), pp. 869-880. Date of Electronic Publication: 2020 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*genetics
Cell Proliferation/*genetics
Liver Neoplasms/*genetics
N-Myc Proto-Oncogene Protein/*genetics
Oncogenes/*genetics
3' Untranslated Regions/genetics ; Aged ; Aged, 80 and over ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Tumor Suppressor/physiology ; Hep G2 Cells ; Humans ; Liver Neoplasms/pathology ; Male ; MicroRNAs ; Middle Aged ; Prognosis ; Proto-Oncogenes/genetics
Czasopismo naukowe
Tytuł :
RP11-81H3.2 Acts as an Oncogene via microRNA-490-3p Inhibition and Consequential Tankyrase 2 Up-Regulation in Hepatocellular Carcinoma.
Autorzy :
Chen W; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Li K; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Zhu K; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Yan R; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Cai QC; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Li WH; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Dang CX; Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China. .
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Źródło :
Digestive diseases and sciences [Dig Dis Sci] 2020 Oct; Vol. 65 (10), pp. 2949-2958. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Oncogenes*
Carcinoma, Hepatocellular/*enzymology
Liver Neoplasms/*enzymology
MicroRNAs/*metabolism
RNA, Long Noncoding/*metabolism
Tankyrases/*biosynthesis
Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Movement ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Hep G2 Cells ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Mice, Nude ; MicroRNAs/genetics ; Neoplasm Invasiveness ; RNA, Long Noncoding/genetics ; Signal Transduction ; Tankyrases/genetics ; Tumor Burden
Czasopismo naukowe
Tytuł :
A compendium of mutational cancer driver genes.
Autorzy :
Martínez-Jiménez F; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Muiños F; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Sentís I; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Deu-Pons J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Reyes-Salazar I; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Arnedo-Pac C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Mularoni L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Pich O; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Bonet J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Kranas H; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Gonzalez-Perez A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain. .; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain. .
Lopez-Bigas N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain. .; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain. .; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain. .
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2020 Oct; Vol. 20 (10), pp. 555-572. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genetic Predisposition to Disease*
Mutation*
Oncogenes*
Neoplasms/*genetics
Animals ; Biomarkers, Tumor ; Cell Transformation, Neoplastic/genetics ; Computational Biology/methods ; Gene Expression Regulation, Neoplastic ; Genetic Association Studies ; Genomics/methods ; Humans ; Neoplasms/diagnosis ; Neoplasms/metabolism ; Neoplasms/therapy ; Signal Transduction ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Oncogenic Smurf1 promotes PTEN wild-type glioblastoma growth by mediating PTEN ubiquitylation.
Autorzy :
Xia Q; School of Life Science, Beijing Institute of Technology, Beijing, China.
Zhang H; School of Life Science, Beijing Institute of Technology, Beijing, China.
Zhang P; School of Life Science, Beijing Institute of Technology, Beijing, China.
Li Y; School of Life Science, Beijing Institute of Technology, Beijing, China.
Xu M; School of Life Science, Beijing Institute of Technology, Beijing, China.
Li X; Tianjin Key Laboratory of Medical Epigenetics, Department of Immunology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.
Li X; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Dong L; School of Life Science, Beijing Institute of Technology, Beijing, China. .
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Źródło :
Oncogene [Oncogene] 2020 Sep; Vol. 39 (36), pp. 5902-5915. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Oncogenes*
Glioblastoma/*genetics
Glioblastoma/*metabolism
PTEN Phosphohydrolase/*genetics
PTEN Phosphohydrolase/*metabolism
Ubiquitin-Protein Ligases/*genetics
Animals ; Cell Line, Tumor ; Disease Models, Animal ; Drug Resistance, Neoplasm ; Gene Deletion ; Gene Expression Profiling ; Genes, Reporter ; Glioblastoma/mortality ; Glioblastoma/pathology ; Heterografts ; Humans ; Immunohistochemistry ; Mice ; Mutation ; Prognosis ; Sirolimus/pharmacology ; Synthetic Lethal Mutations ; Ubiquitination
Czasopismo naukowe
Tytuł :
[Armand Tavitian (1931-2020): from oncogenes to the Ras superfamily].
Autorzy :
Moreau-Gachelin F; Directeur de recherche honoraire à l'Inserm, Paris, France.
Camonis J; Directeur de recherche émérite au CNRS, Paris, France.
de Gunzburg J; Directeur scientifique de la société biopharmaceutique DaVolterra, Paris, France.
Goud B; Directeur de recherche au CNRS, Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex, France.
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Transliterated Title :
Armand Tavitian (1931-2020) - Des oncogènes à la superfamille Ras.
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2020 Aug-Sep; Vol. 36 (8-9), pp. 810-812. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Biography; Historical Article; Journal Article; Portrait
MeSH Terms :
Biomedical Research*/history
Genes, ras*
Medical Oncology*/history
Oncogenes*
Physicians*
France ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/pathology ; History, 20th Century ; History, 21st Century ; Humans ; Medical Laboratory Personnel ; Molecular Biology/history ; Multigene Family
Personal Name as Subject :
Tavitian A
Czasopismo naukowe
Tytuł :
Oncogenic splicing regulated by phase separation.
Autorzy :
Liu B; Human Oncology and Pathogenesis Program, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Abdel-Wahab O; Human Oncology and Pathogenesis Program, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2020 Aug; Vol. 22 (8), pp. 916-918.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Oncogenes*
RNA Splicing*
Carcinogenesis ; Humans
Czasopismo naukowe
Tytuł :
Applications of CRISPR/Cas9 Technology in the Treatment of Lung Cancer.
Autorzy :
Jiang C; Department of Thoracic Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin 300121, People's Republic of China. Electronic address: .
Lin X; Department of Physics and Chemistry, Tianjin Centres for Disease Control and Prevention, Tianjin 300011, People's Republic of China.
Zhao Z; Department of Hematology and Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, People's Republic of China. Electronic address: .
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Źródło :
Trends in molecular medicine [Trends Mol Med] 2019 Nov; Vol. 25 (11), pp. 1039-1049. Date of Electronic Publication: 2019 Aug 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
CRISPR-Cas Systems*
Lung Neoplasms*/diagnosis
Lung Neoplasms*/genetics
Lung Neoplasms*/therapy
Gene Editing/*methods
Oncogenes/*genetics
Animals ; B7-H1 Antigen/genetics ; CRISPR-Associated Protein 9 ; Drug Resistance/genetics ; ErbB Receptors/genetics ; Gene Editing/trends ; Gene Frequency ; Gene Silencing ; Genes, Tumor Suppressor ; Genetic Therapy/methods ; Genetic Therapy/trends ; Humans ; MicroRNAs/genetics ; Models, Animal ; Molecular Targeted Therapy/trends ; Mutation Rate ; Precision Medicine/trends ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Proto-Oncogenes/genetics ; T-Lymphocytes/metabolism ; gamma Catenin/genetics
Czasopismo naukowe
Tytuł :
FCHSD2 controls oncogenic ERK1/2 signaling outcome by regulating endocytic trafficking.
Autorzy :
Xiao GY; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Schmid SL; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
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Źródło :
PLoS biology [PLoS Biol] 2020 Jul 17; Vol. 18 (7), pp. e3000778. Date of Electronic Publication: 2020 Jul 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Endocytosis*
MAP Kinase Signaling System*
Oncogenes*
Carcinoma, Non-Small-Cell Lung/*pathology
Carrier Proteins/*metabolism
Lung Neoplasms/*pathology
Membrane Proteins/*metabolism
Carcinoma, Non-Small-Cell Lung/enzymology ; Cell Line, Tumor ; Disease Progression ; Endosomes/metabolism ; ErbB Receptors/metabolism ; Gene Knockdown Techniques ; Humans ; Lung Neoplasms/enzymology ; Protein Transport ; Proto-Oncogene Proteins c-met/metabolism ; Receptors, Transferrin/metabolism ; Up-Regulation ; rab GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms.
Autorzy :
Nadeu F; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. .; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. .
Mas-de-Les-Valls R; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Navarro A; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Royo R; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
Martín S; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Villamor N; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hospital Clínic of Barcelona, Barcelona, Spain.
Suárez-Cisneros H; Unitat de Genòmica, IDIBAPS, Barcelona, Spain.
Mares R; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Lu J; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Enjuanes A; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Unitat de Genòmica, IDIBAPS, Barcelona, Spain.
Rivas-Delgado A; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Hospital Clínic of Barcelona, Barcelona, Spain.
Aymerich M; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hospital Clínic of Barcelona, Barcelona, Spain.
Baumann T; Hospital Clínic of Barcelona, Barcelona, Spain.
Colomer D; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hospital Clínic of Barcelona, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.
Delgado J; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hospital Clínic of Barcelona, Barcelona, Spain.
Morin RD; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada.; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada.
Zenz T; Department of Medical Oncology and Hematology, University Hospital and University of Zürich, Zürich, Switzerland.
Puente XS; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Campbell PJ; Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK.
Beà S; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Universitat de Barcelona, Barcelona, Spain.
Maura F; Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK.; Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Campo E; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Hospital Clínic of Barcelona, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.
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Źródło :
Nature communications [Nat Commun] 2020 Jul 07; Vol. 11 (1), pp. 3390. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, Immunoglobulin*
Oncogenes*
Translocation, Genetic*
In Situ Hybridization, Fluorescence/*methods
Algorithms ; Cohort Studies ; Genome, Human ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/immunology ; High-Throughput Nucleotide Sequencing ; Humans ; Immunoglobulin Class Switching ; Lymphoma, B-Cell/genetics ; Lymphoma, B-Cell/immunology ; Software ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties.
Autorzy :
Panciera T; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Citron A; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Di Biagio D; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Battilana G; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Gandin A; Department of Industrial Engineering and INSTM, University of Padua, Padua, Italy.
Giulitti S; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Forcato M; Center for Genome Research, Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Bicciato S; Center for Genome Research, Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Panzetta V; Interdisciplinary Research Centre on Biomaterials, CRIB, University of Naples Federico II, Naples, Italy.; Center for Advanced Biomaterials for Health Care , Istituto Italiano di Tecnologia, Naples, Italy.
Fusco S; Interdisciplinary Research Centre on Biomaterials, CRIB, University of Naples Federico II, Naples, Italy.; Center for Advanced Biomaterials for Health Care , Istituto Italiano di Tecnologia, Naples, Italy.
Azzolin L; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Totaro A; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy.
Dei Tos AP; Department of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, Padua, Italy.
Fassan M; Department of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, Padua, Italy.
Vindigni V; Clinic of Plastic Surgery, Padua University Hospital, Padua, Italy.
Bassetto F; Clinic of Plastic Surgery, Padua University Hospital, Padua, Italy.
Rosato A; Istituto Oncologico Veneto IOV-IRCCS, and Department of Surgery, Oncology and Gastroenterology, University of Padua School of Medicine, Padua, Italy.
Brusatin G; Department of Industrial Engineering and INSTM, University of Padua, Padua, Italy.
Cordenonsi M; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy. .
Piccolo S; Department of Molecular Medicine, University of Padua School of Medicine, Padua, Italy. .; IFOM, The FIRC Institute of Molecular Oncology, Padua, Italy. .
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Źródło :
Nature materials [Nat Mater] 2020 Jul; Vol. 19 (7), pp. 797-806. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cellular Reprogramming/*physiology
Extracellular Matrix/*physiology
Oncogenes/*physiology
Animals ; Biomechanical Phenomena ; Cell Line, Tumor ; Female ; Gene Expression Regulation ; Humans ; Mammary Glands, Human/cytology ; Mammary Glands, Human/metabolism ; Mice ; Mice, Inbred Strains ; Mice, Knockout ; Microscopy/methods ; Oncogenes/genetics ; Pancreas/cytology ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
miR-487a performs oncogenic functions in osteosarcoma by targeting BTG2 mRNA.
Autorzy :
Gu Z; Department of Orthopedics, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo 315000, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo 315000, China.
Wu S; Department of Orthopedics, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo 315000, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo 315000, China.
Xu G; Department of Orthopedics, Third Affiliated Hospital, Naval Medical University, Shanghai 200438, China.
Wu W; Department of Orthopedics, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo 315000, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo 315000, China.
Mao B; Department of Orthopedics, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo 315000, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo 315000, China.
Zhao S; Department of Orthopedics, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo 315000, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo 315000, China.
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Źródło :
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2020 Jun 20; Vol. 52 (6), pp. 631-637.
Typ publikacji :
Journal Article
MeSH Terms :
Oncogenes*
Bone Neoplasms/*metabolism
Immediate-Early Proteins/*biosynthesis
MicroRNAs/*metabolism
Osteosarcoma/*metabolism
RNA, Messenger/*biosynthesis
RNA, Neoplasm/*metabolism
Tumor Suppressor Proteins/*biosynthesis
Animals ; Bone Neoplasms/genetics ; Bone Neoplasms/pathology ; Cell Line, Tumor ; Female ; Humans ; Immediate-Early Proteins/genetics ; Male ; Mice ; Mice, Nude ; MicroRNAs/genetics ; Osteosarcoma/genetics ; Osteosarcoma/pathology ; RNA, Messenger/genetics ; RNA, Neoplasm/genetics ; Tumor Suppressor Proteins/genetics
Czasopismo naukowe
Tytuł :
4D Genome Rewiring during Oncogene-Induced and Replicative Senescence.
Autorzy :
Sati S; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France.
Bonev B; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France.
Szabo Q; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France.
Jost D; Univ Grenoble Alpes, CNRS, Grenoble INP, TIMC-IMAG, 38000 Grenoble, France.
Bensadoun P; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France.
Serra F; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain.
Loubiere V; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France.
Papadopoulos GL; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France.
Rivera-Mulia JC; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Fritsch L; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France.
Bouret P; Unit of Chromosomal Genetics and Chromostem Research Platform, CHU, Montpellier, France.
Castillo D; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain.
Gelpi JL; Barcelona Supercomputing Center, Barcelona, Spain; Department of Biochemistry and Molecular Biomedicine, University of Barcelona, Barcelona, Spain.
Orozco M; Department of Biochemistry and Molecular Biomedicine, University of Barcelona, Barcelona, Spain; Institute for Research in Biomedicine, the Barcelona Institute of Science and Technology, Barcelona, Spain.
Vaillant C; Laboratoire de Physique (UMR CNRS 5672), ENS de Lyon, Lyon, France.
Pellestor F; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France; Unit of Chromosomal Genetics and Chromostem Research Platform, CHU, Montpellier, France.
Bantignies F; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France.
Marti-Renom MA; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain; Centre for Genomic Regulation, The Barcelona Institute for Science and Technology, Carrer del Doctor Aiguader 88, Barcelona 08003, Spain; Pompeu Fabra University, Doctor Aiguader 88, Barcelona 08003, Spain; CREA, PgLluís Companys 23, 08010 Barcelona, Spain.
Gilbert DM; Department of Biological Science and Center for Genomics and Personalized Medicine, Florida State University, Tallahassee, FL 32306, USA.
Lemaitre JM; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France; CHRU de Montpellier, Montpellier, France. Electronic address: .
Cavalli G; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 May 07; Vol. 78 (3), pp. 522-538.e9. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome, Human*
Oncogenes*
Cellular Senescence/*genetics
DNA (Cytosine-5-)-Methyltransferase 1/*genetics
Cells, Cultured ; Chromatin Assembly and Disassembly/genetics ; DNA (Cytosine-5-)-Methyltransferase 1/metabolism ; DNA Methylation ; Fibroblasts ; Heterochromatin/genetics ; Humans ; In Situ Hybridization, Fluorescence
Czasopismo naukowe
Tytuł :
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
Autorzy :
Zeng Y; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China; Basic Medical School of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Guo Z; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Hu Z; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Liu M; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Chen Y; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Chen S; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Peng B; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Zhang P; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Wu Z; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Luo H; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Zhong F; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Jiang K; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Lu Y; School of Medicine, Southern University of Science and Technology, 1088 Xili Xueyuan Avenue, Shenzhen, 518055, Guangdong, China. Electronic address: .
Yuan G; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China. Electronic address: .
He S; Division of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 May; Vol. 125, pp. 110029. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Oncogenes*
Autophagy/*genetics
Carcinoma, Hepatocellular/*etiology
Guanine Nucleotide Exchange Factors/*genetics
Liver Neoplasms/*etiology
Mitochondria/*genetics
Adult ; Aged ; Animals ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Disease Models, Animal ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Guanine Nucleotide Exchange Factors/metabolism ; Heterografts ; Humans ; Immunohistochemistry ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Male ; Mice ; Middle Aged ; Mitochondria/metabolism ; Neoplasm Grading ; Neoplasm Staging
Czasopismo naukowe
Tytuł :
Antitumor Effects of Pan-RAF Inhibitor LY3009120 Against Lung Cancer Cells Harboring Oncogenic BRAF Mutation.
Autorzy :
Miyauchi S; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Shien K; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan .
Takeda T; Department of Clinical Pharmacy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Araki K; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Nakata K; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Miura A; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Takahashi Y; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Kurihara E; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Ogoshi Y; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Namba K; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Suzawa K; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Yamamoto H; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Okazaki M; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Soh J; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Tomida S; Center for Comprehensive Genomic Medicine, Okayama University Hospital, Okayama, Japan.
Yamane M; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Sakaguchi M; Department of Cell Biology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Toyooka S; Department of General Thoracic, Breast, and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2020 May; Vol. 40 (5), pp. 2667-2673.
Typ publikacji :
Journal Article
MeSH Terms :
Oncogenes*
Antineoplastic Agents/*pharmacology
Lung Neoplasms/*genetics
Mutation/*genetics
Phenylurea Compounds/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Proto-Oncogene Proteins B-raf/*genetics
Pyrimidines/*pharmacology
Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Humans ; Inhibitory Concentration 50 ; Mice, Inbred BALB C ; Mice, Nude ; Signal Transduction/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Clinical relevance of ARF/ARL family genes and oncogenic function of ARL4C in endometrial cancer.
Autorzy :
Zhang J; Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhang Q; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Sun C; Department of Obstetrics and Gynecology, First Hospital of Zibo, Shandong, China.
Huang Y; School of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Zhang J; Department of Integrated Therapy, Shanghai Cancer Center, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: .
Wang Q; Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 May; Vol. 125, pp. 110000. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Multigene Family*
Oncogenes*
ADP-Ribosylation Factors/*genetics
Cell Transformation, Neoplastic/*genetics
Endometrial Neoplasms/*genetics
ADP-Ribosylation Factors/metabolism ; Cell Adhesion/genetics ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation ; Computational Biology/methods ; Endometrial Neoplasms/metabolism ; Endometrial Neoplasms/mortality ; Endometrial Neoplasms/pathology ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Metformin/pharmacology ; Prognosis
Czasopismo naukowe

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