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Wyszukujesz frazę ""osteoporosis"" wg kryterium: Temat


Starter badań:

Tytuł:
Modeling osteoporosis to design and optimize pharmacological therapies comprising multiple drug types.
Autorzy:
Jörg DJ; Biomedical Modeling and Simulation Group, Global Research and Development, Fresenius Medical Care Germany, Bad Homburg, Germany.
Fuertinger DH; Biomedical Modeling and Simulation Group, Global Research and Development, Fresenius Medical Care Germany, Bad Homburg, Germany.
Cherif A; Renal Research Institute, New York, United States.
Bushinsky DA; Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, United States.
Mermelstein A; Renal Research Institute, New York, United States.
Raimann JG; Renal Research Institute, New York, United States.
Kotanko P; Renal Research Institute, New York, United States.; Icahn School of Medicine at Mount Sinai, New York, United States.
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Źródło:
ELife [Elife] 2022 Aug 09; Vol. 11. Date of Electronic Publication: 2022 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Density Conservation Agents*/therapeutic use
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/drug therapy
Bone Density ; Diphosphonates/therapeutic use ; Drug Combinations ; Female ; Humans
Czasopismo naukowe
Tytuł:
Efficacy and Safety of Romosozumab Among Postmenopausal Women With Osteoporosis and Mild-to-Moderate Chronic Kidney Disease.
Autorzy:
Miller PD; Colorado Center for Bone Health, Lakewood, CO, USA.
Adachi JD; St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, Canada.
Albergaria BH; Federal University of Espirito Santo, Espirito Santo Research and Osteoporosis Center, Vitória, Brazil.
Cheung AM; Department of Medicine, University Health Network, University of Toronto, Toronto, Canada.
Chines AA; Amgen Inc., Thousand Oaks, CA, USA.
Gielen E; Gerontology and Geriatrics, Department of Public Health and Primary Care, KU Leuven & Center for Metabolic Bone Diseases, UZ Leuven, Leuven, Belgium.
Langdahl BL; Aarhus University Hospital, Aarhus, Denmark.
Miyauchi A; Miyauchi Medical Center, Osaka, Japan.
Oates M; Amgen Inc., Thousand Oaks, CA, USA.
Reid IR; University of Auckland, Auckland, New Zealand.
Santiago NR; Amgen Inc., Thousand Oaks, CA, USA.
Vanderkelen M; UCB S.A, Brussels, Belgium.
Wang Z; Amgen Inc., Thousand Oaks, CA, USA.
Yu Z; Amgen Inc., Thousand Oaks, CA, USA.
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Źródło:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2022 Aug; Vol. 37 (8), pp. 1437-1445. Date of Electronic Publication: 2022 May 20.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Bone Density Conservation Agents*/adverse effects
Fractures, Bone*/epidemiology
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/drug therapy
Renal Insufficiency, Chronic*/complications
Renal Insufficiency, Chronic*/drug therapy
Alendronate/pharmacology ; Antibodies, Monoclonal ; Bone Density ; Female ; Femur Neck ; Humans ; Postmenopause
Czasopismo naukowe
Tytuł:
Osteoporosis among Postmenopausal Women in Jordan: A National Cross-Sectional Study.
Autorzy:
Saadeh R; Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Jumaa D; Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Elsalem L; Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Batieha A; Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Jaddou H; Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Khader Y; Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
El-Khateeb M; The National Center (Institute) for Diabetes, Endocrinology and Genetics, University of Jordan, Amman 11942, Jordan.
Ajlouni K; The National Center (Institute) for Diabetes, Endocrinology and Genetics, University of Jordan, Amman 11942, Jordan.
Allouh MZ; Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.; Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates.
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Źródło:
International journal of environmental research and public health [Int J Environ Res Public Health] 2022 Jul 20; Vol. 19 (14). Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoporosis*/epidemiology
Osteoporosis, Postmenopausal*/epidemiology
Osteoporosis, Postmenopausal*/prevention & control
Aged ; Bone Density ; Calcium ; Calcium, Dietary ; Cross-Sectional Studies ; Female ; Humans ; Jordan/epidemiology ; Male ; Postmenopause ; Vitamin D
Czasopismo naukowe
Tytuł:
Puerarin improves OVX-induced osteoporosis by regulating phospholipid metabolism and biosynthesis of unsaturated fatty acids based on serum metabolomics.
Autorzy:
Li B; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.
Wang Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.
Gong S; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, China.
Yao W; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, China.
Gao H; Division of Pharmacology Laboratory, National Institutes for Food and Drug Control, Beijing, China.
Liu M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, China. Electronic address: .
Wei M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China; Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, Shenyang, China; Liaoning Medical Diagnosis and Treatment Center, Shenyang, China. Electronic address: minjie_.
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2022 Jul 20; Vol. 102, pp. 154198. Date of Electronic Publication: 2022 May 21.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoporosis*/metabolism
Osteoporosis, Postmenopausal*/drug therapy
Animals ; Fatty Acids, Unsaturated ; Female ; Humans ; Isoflavones ; Lipid Metabolism ; Metabolomics ; Osteogenesis ; Ovariectomy/adverse effects ; PPAR gamma/metabolism ; Phospholipids ; Rats
Czasopismo naukowe
Tytuł:
Factors influencing self-care in postmenopausal women with osteoporosis: The Guardian Angel® multicentric longitudinal study.
Autorzy:
Cittadini N; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Basilici Zannetti E; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy. Electronic address: .
Iovino P; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy; School of Nursing, Midwifery and Paramedicine Faculty of Health Science, Australian Catholic University, Melbourne, Australia.
De Maria M; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
D'Angelo D; National Center for Clinical Excellence, Healthcare Quality and Safety, Istituto Superiore di Sanità, Rome, Italy.
Pennini A; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Vellone E; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Alvaro R; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
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Źródło:
Maturitas [Maturitas] 2022 Jul; Vol. 161, pp. 7-11. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Fractures, Bone*/epidemiology
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/drug therapy
Aged ; Bone Density ; Female ; Humans ; Longitudinal Studies ; Postmenopause ; Risk Factors ; Self Care
Czasopismo naukowe
Tytuł:
Efficacy and safety of the biosimilar denosumab candidate (Arylia) compared to the reference product (Prolia®) in postmenopausal osteoporosis: a phase III, randomized, two-armed, double-blind, parallel, active-controlled, and noninferiority clinical trial.
Autorzy:
Jamshidi A; Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Vojdanian M; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Soroush M; Rheumatology Department, AJA University of Medical Sciences, Tehran, Iran.
Akbarian M; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Aghaei M; Golestan Rheumatology Research Center (GRRC), Golestan University of Medical Sciences, Gorgan, Iran.
Hajiabbasi A; Department of Rheumatology, Guilan Rheumatology Research Center, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Mirfeizi Z; Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Khabbazi A; Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Alishiri G; Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Haghighi A; Rheumatology Department, Iran University of Medical Sciences, Tehran, Iran.
Salimzadeh A; Rheumatology Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Karimzadeh H; Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Shirani F; Department of Rheumatology, Iran University of Medical Sciences, Tehran, Iran.
Fard MRH; Rheumatology Ward, Internal Medicine Department, Mashhad University of Medical Sciences, Mashhad, Iran.
Nazarinia M; Shiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Soroosh S; Rheumatology Department, AJA University of Medical Sciences, Tehran, Iran.
Anjidani N; Medical Department, Orchid Pharmed Company, Tehran, Iran.
Gharibdoost F; Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .
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Źródło:
Arthritis research & therapy [Arthritis Res Ther] 2022 Jun 30; Vol. 24 (1), pp. 161. Date of Electronic Publication: 2022 Jun 30.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Biosimilar Pharmaceuticals*/adverse effects
Bone Density Conservation Agents*/adverse effects
Osteoporosis*
Osteoporosis, Postmenopausal*/drug therapy
Bone Density ; Denosumab/adverse effects ; Double-Blind Method ; Female ; Humans
Czasopismo naukowe
Tytuł:
N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling.
Autorzy:
Zeng Q; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Xu R; Department of Orthopaedics, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Ling H; Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Zhao S; The College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Wang X; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Yuan W; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Gu M; The College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Xu T; Department of Orthopaedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Wang P; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Ruan H; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Jin H; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Qu H; Department of Orthopaedic Surgery, Zhejiang Hospital, Hangzhou, China.
Ye F; Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Chen J; Institute of Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Jun 24; Vol. 13, pp. 925848. Date of Electronic Publication: 2022 Jun 24 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/drug therapy
1-Butanol/pharmacology ; Animals ; Female ; Humans ; Mice ; NF-kappa B ; Osteogenesis ; Ovariectomy ; X-Ray Microtomography
Czasopismo naukowe
Tytuł:
Dipeptidyl Peptidase 3 Activity as a Promising Biomarker of Bone Fragility in Postmenopausal Women.
Autorzy:
Menale C; IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', Via Pansini 5, 80131 Napoli, Italy.
Tabacco G; Unit of Metabolic Bone and Thyroid Disorders, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.; Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Naciu AM; Unit of Metabolic Bone and Thyroid Disorders, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.; Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Schiavone ML; IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.
Cannata F; Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Morenghi E; Biostatistics Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.
Sobacchi C; IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.; CNR-IRGB, Milan Unit, Via Fantoli 16/15, 20138 Milan, Italy.
Palermo A; Unit of Metabolic Bone and Thyroid Disorders, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.; Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 19; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 19.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Density Conservation Agents*/pharmacology
Bone Density Conservation Agents*/therapeutic use
Osteoporosis*
Osteoporosis, Postmenopausal*/drug therapy
Osteoporosis, Postmenopausal*/genetics
Animals ; Biomarkers ; Bone Density ; Cross-Sectional Studies ; Denosumab/metabolism ; Denosumab/pharmacology ; Denosumab/therapeutic use ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Female ; Humans ; Kelch-Like ECH-Associated Protein 1/metabolism ; Mice ; NF-E2-Related Factor 2/metabolism ; Postmenopause ; Prospective Studies
Czasopismo naukowe
Tytuł:
Prevention and Treatment of Glucocorticoid-Induced Osteoporosis in Adults: Consensus Recommendations From the Belgian Bone Club.
Autorzy:
Laurent MR; Centre for Metabolic Bone Diseases, Department of Geriatrics, University Hospitals Leuven, Leuven, Belgium.; Department of Geriatrics, Imelda Hospital, Bonheiden, Belgium.
Goemaere S; Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium.
Verroken C; Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium.; Department of Endocrinology and Metabolism, Ghent University Hospital, Ghent, Belgium.
Bergmann P; Department of Nuclear Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Body JJ; Department of Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Bruyère O; WHO Collaborating Center for Public Health Aspects of Musculoskeletal Health and Ageing, Division of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Cavalier E; Department of Clinical Chemistry, University of Liège, CHU de Liège, Liège, Belgium.
Rozenberg S; Department of Gynaecology and Obstetrics, Université Libre de Bruxelles, Brussels, Belgium.
Lapauw B; Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium.; Department of Endocrinology and Metabolism, Ghent University Hospital, Ghent, Belgium.
Gielen E; Centre for Metabolic Bone Diseases, Department of Geriatrics, University Hospitals Leuven, Leuven, Belgium.; Gerontology and Geriatrics section, Department of Public Health and Primary Care, University Hospitals Leuven and KU Leuven, Leuven, Belgium.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Jun 09; Vol. 13, pp. 908727. Date of Electronic Publication: 2022 Jun 09 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Fractures, Bone*/etiology
Fractures, Bone*/prevention & control
Osteoporosis*/chemically induced
Osteoporosis*/drug therapy
Belgium/epidemiology ; Calcium ; Consensus ; Glucocorticoids/adverse effects ; Humans
Czasopismo naukowe
Tytuł:
Sociodemographic factors affecting the disease acceptance in the group of women with postmenopausal osteoporosis.
Autorzy:
Górczewska B; Medical University of Lodz, Łódź, Poland (Department of Pediatrics, Neonatal Pathology and Bone Metabolism Diseases).
Jakubowska-Pietkiewicz E; Medical University of Lodz, Łódź, Poland (Department of Pediatrics, Neonatal Pathology and Bone Metabolism Diseases).
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Źródło:
International journal of occupational medicine and environmental health [Int J Occup Med Environ Health] 2022 Jun 08; Vol. 35 (3), pp. 273-283. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoporosis*
Osteoporosis, Postmenopausal*/diagnosis
Osteoporosis, Postmenopausal*/psychology
Aged ; Educational Status ; Female ; Humans ; Sociodemographic Factors ; Surveys and Questionnaires
Czasopismo naukowe
Tytuł:
Cardiovascular Safety and Effectiveness of Bisphosphonates: From Intervention Trials to Real-Life Data.
Autorzy:
Delli Poggi C; Bone Metabolic Diseases Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, 50139 Florence, Italy.
Fusaro M; National Research Council (CNR), Institute of Clinical Physiology (IFC), 56124 Pisa, Italy.; Department of Medicine, University of Padova, 35128 Padova, Italy.
Mereu MC; Independent Researcher, 09100 Cagliari, Italy.
Brandi ML; F.I.R.M.O. Italian Foundation for the Research on Bone Diseases, 50141 Florence, Italy.
Cianferotti L; Bone Metabolic Diseases Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, 50139 Florence, Italy.
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Źródło:
Nutrients [Nutrients] 2022 Jun 07; Vol. 14 (12). Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article; Meta-Analysis; Review
MeSH Terms:
Bone Density Conservation Agents*/adverse effects
Cardiovascular Diseases*/complications
Fractures, Bone*/etiology
Fractures, Bone*/prevention & control
Osteoporosis*/complications
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/drug therapy
Aged ; Diphosphonates/adverse effects ; Female ; Humans
Czasopismo naukowe
Tytuł:
Real-World Safety and Effectiveness of Denosumab in Patients with Osteoporosis: A Prospective, Observational Study in South Korea.
Autorzy:
Rhee Y; Department of Internal Medicine, Severance Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Chang DG; Department of Orthopedic Surgery, Inje University Sanggye Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
Ha J; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim S; Amgen Korea Ltd., Seoul, Korea.
Lee Y; Amgen Korea Ltd., Seoul, Korea.
Jo E; Amgen Korea Ltd., Seoul, Korea.
Koh JM; Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
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Źródło:
Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2022 Jun; Vol. 37 (3), pp. 497-505. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Observational Study; Randomized Controlled Trial
MeSH Terms:
Bone Density Conservation Agents*/adverse effects
Osteoporosis*/chemically induced
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/chemically induced
Osteoporosis, Postmenopausal*/complications
Osteoporosis, Postmenopausal*/drug therapy
Aged ; Denosumab/adverse effects ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Tytuł:
Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF-κB Signaling Pathway.
Autorzy:
Yuan SG; Department of Orthopaedic, Hainan Province Hospital of Traditional Chinese Medicine, Haikou, Hainan, China.; Center for Orthopaedic Surgery, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Hu HL; Center for Orthopaedic Surgery, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Wang XJ; Department of Spine Surgery, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Yang JC; Department of Spinal Surgery, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Zhou RP; Center for Orthopaedic Surgery, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Bai XC; Center for Orthopaedic Surgery, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Lai PL; Center for Orthopaedic Surgery, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China.
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Źródło:
Orthopaedic surgery [Orthop Surg] 2022 Jun; Vol. 14 (6), pp. 1203-1216. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Diseases, Metabolic*
Bone Resorption*
Osteoporosis*/drug therapy
Osteoporosis*/metabolism
Osteoporosis, Postmenopausal*/metabolism
Animals ; Cell Differentiation ; Chemokine CCL2 ; Chemokine CCL7 ; Cytokines/metabolism ; Female ; Humans ; I-kappa B Kinase/metabolism ; I-kappa B Kinase/pharmacology ; Indazoles ; Mice ; NF-kappa B/metabolism ; Osteoclasts ; Osteogenesis ; Ovariectomy ; Propionates ; RNA, Messenger/metabolism ; Signal Transduction ; X-Ray Microtomography
Czasopismo naukowe
Tytuł:
Granular PEG hydrogels mediate osteoporotic MSC clustering via N-cadherin influencing the pro-resorptive bias of their secretory profile.
Autorzy:
Rao VV; Department of Chemical and Biological Engineering, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States; BioFrontiers Institute, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States.
Wechsler ME; Department of Biomedical Engineering and Chemical Engineering, University of Texas San Antonio, One UTSA Circle, San Antonio, TX 78249, United States.
Cravens E; Department of Biomedical Engineering, University of Massachusetts Amherst, 240 Thatcher Road, Amherst, MA 01003, United States.
Wojda SJ; Department of Biomedical Engineering, University of Massachusetts Amherst, 240 Thatcher Road, Amherst, MA 01003, United States.
Caldwell AS; Department of Chemical and Biological Engineering, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States; BioFrontiers Institute, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States.
Kirkpatrick BE; Department of Chemical and Biological Engineering, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States; BioFrontiers Institute, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States; Medical Scientist Training Program, University of Colorado Anschutz Medical Campus, 13001 East 17th Aurora, CO 80045, United States.
Donahue SW; Department of Biomedical Engineering, University of Massachusetts Amherst, 240 Thatcher Road, Amherst, MA 01003, United States.
Anseth KS; Department of Chemical and Biological Engineering, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States; BioFrontiers Institute, University of Colorado - Boulder, 3415 Colorado Avenue, Boulder, CO 80303, United States. Electronic address: .
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Źródło:
Acta biomaterialia [Acta Biomater] 2022 Jun; Vol. 145, pp. 77-87. Date of Electronic Publication: 2022 Apr 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Cadherins*/metabolism
Hydrogels*/pharmacology
Osteoporosis*/therapy
Osteoporosis, Postmenopausal*/complications
Animals ; Female ; Humans ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Mesenchymal Stem Cells/pathology ; Ovariectomy/adverse effects ; Polyethylene Glycols/pharmacology ; Rats ; Rats, Sprague-Dawley ; Secretome/drug effects ; Secretome/metabolism ; Tissue Inhibitor of Metalloproteinase-1
Czasopismo naukowe
Tytuł:
Osteoporosis and periodontal diseases - An update on their association and mechanistic links.
Autorzy:
Yu B; Division of Regenerative and Constitutive Sciences, School of Dentistry, University of California at Los Angeles, Los Angeles, California, USA.
Wang CY; Division of Oral Biology and Medicine, School of Dentistry, University of California at Los Angeles, Los Angeles, California, USA.; Department of Bioengineering, Henry Samueli School of Engineering and Applied Science, Broad Stem Cell Research Center and Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, USA.
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Źródło:
Periodontology 2000 [Periodontol 2000] 2022 Jun; Vol. 89 (1), pp. 99-113. Date of Electronic Publication: 2022 Mar 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alveolar Bone Loss*/complications
Osteoporosis*/complications
Osteoporosis*/drug therapy
Osteoporosis, Postmenopausal*/complications
Osteoporosis, Postmenopausal*/drug therapy
Periodontal Diseases*/complications
Periodontal Diseases*/therapy
Periodontitis*/complications
Periodontitis*/therapy
Aged ; Bone Density/physiology ; Female ; Humans ; Inflammation/complications
Czasopismo naukowe
Tytuł:
Promotion of osteogenesis by Sweroside via BMP2-involved signaling in postmenopausal osteoporosis.
Autorzy:
Choi Y; Department of Convergence Korean Medical Science, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Kim MH; Department of Convergence Korean Medical Science, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Yang WM; Department of Convergence Korean Medical Science, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
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Źródło:
Phytotherapy research : PTR [Phytother Res] 2021 Dec; Vol. 35 (12), pp. 7050-7063. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Morphogenetic Protein 2*
Seminal Vesicle Secretory Proteins*
Iridoid Glucosides/*pharmacology
Osteoporosis/*drug therapy
Animals ; Cell Differentiation ; Disease Models, Animal ; Female ; Humans ; Mice ; Osteoblasts ; Osteogenesis ; Osteoporosis, Postmenopausal ; Signal Transduction
Czasopismo naukowe
Tytuł:
Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin signaling pathway.
Autorzy:
Zhang M; Department of Oral Implantology, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China.; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Gao Y; Department of Oral Implantology, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China.; Department of Oral and Maxillofacial Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Li Q; Luzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China.
Cao H; Department of Oral Implantology, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China.
Yang J; Luzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China.
Cai X; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China. .
Xiao J; Department of Oral Implantology, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China. .; Department of Oral and Maxillofacial Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China. .; Luzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2022 Aug 04; Vol. 13 (1), pp. 397. Date of Electronic Publication: 2022 Aug 04.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus*/genetics
Osteoporosis*/drug therapy
Osteoporosis*/therapy
Animals ; Cell Differentiation/physiology ; Cells, Cultured ; DNA/metabolism ; DNA Methyltransferase 3A ; Down-Regulation ; Epigenesis, Genetic ; Mice ; Mice, Inbred C57BL ; Osteogenesis ; RNA, Small Interfering/metabolism ; Stem Cells/metabolism ; Wnt Signaling Pathway/genetics ; X-Ray Microtomography ; beta Catenin/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
Bone health and glucocorticoid-containing lymphoma therapy - a review of risk factors and preventative measures.
Autorzy:
Eyre TA; Department of Haematology, Haematology and Cancer Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Jensen P; Department of Haematology, Clinical Cancer Research Centre, Aalborg University Hospital, Aalborg, Denmark.
Booth S; Department of Haematology, Royal Berkshire Hospital NHS Foundation Trust, Reading, UK.
El-Galaly TC; Department of Haematology, Clinical Cancer Research Centre, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
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Źródło:
British journal of haematology [Br J Haematol] 2022 Aug; Vol. 198 (3), pp. 431-442. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphoma*/drug therapy
Osteoporosis*/chemically induced
Osteoporosis*/prevention & control
Bone Density ; Glucocorticoids/adverse effects ; Humans ; Prospective Studies ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł:
Expression profile analysis of lncRNA in bone marrow mesenchymal stem cells exosomes of postmenopausal osteoporosis patients through microarray and bioinformatics analyses.
Autorzy:
Wang J; Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Fu M; Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
He S; Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Cai P; Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Xiang X; Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Fang L; Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China. Electronic address: .
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Źródło:
Pathology, research and practice [Pathol Res Pract] 2022 Aug; Vol. 236, pp. 153985. Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*/genetics
Exosomes*/metabolism
Mesenchymal Stem Cells*/metabolism
Osteoporosis, Postmenopausal*/genetics
Osteoporosis, Postmenopausal*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Bone Marrow Cells/metabolism ; Computational Biology ; Female ; Humans ; Phosphatidylinositol 3-Kinases/metabolism
Czasopismo naukowe
Tytuł:
Activation of farnesoid X receptor signaling by geniposidic acid promotes osteogenesis.
Autorzy:
Liu M; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China; Clinical Research Platform for Interdiscipline of Stomatology, The First Affiliated Hospital of Jinan University & Department of Stomatology, Jinan University, Guangzhou, 510632, China; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Jin F; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Zhang S; Department of Oral Implantology, School of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai, 200072, China.
Li S; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Zhu D; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Cui Y; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Cai M; Clinical Research Platform for Interdiscipline of Stomatology, The First Affiliated Hospital of Jinan University & Department of Stomatology, Jinan University, Guangzhou, 510632, China.
Liu X; Clinical Research Platform for Interdiscipline of Stomatology, The First Affiliated Hospital of Jinan University & Department of Stomatology, Jinan University, Guangzhou, 510632, China.
Zhang Y; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Sun Y; Department of Oral Implantology, School of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai, 200072, China. Electronic address: .
Liu C; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.. Electronic address: .
Wang X; Key Laboratory of Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, 100191, China; Clinical Research Platform for Interdiscipline of Stomatology, The First Affiliated Hospital of Jinan University & Department of Stomatology, Jinan University, Guangzhou, 510632, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2022 Aug; Vol. 103, pp. 154258. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Iridoid Glucosides*/pharmacology
Osteogenesis*
Osteoporosis*/drug therapy
Osteoporosis*/metabolism
Receptors, Cytoplasmic and Nuclear*/metabolism
Animals ; Cell Differentiation ; Female ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Molecular Docking Simulation ; Osteoblasts ; Ovariectomy
Czasopismo naukowe

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