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Tytuł :
CDKN2A deletions are associated with poor outcomes in 101 adults with T-cell acute lymphoblastic leukemia.
Autorzy :
Wang HP; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Zhou YL; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Huang X; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Zhang Y; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Qian JJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Li JH; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Li XY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Li CY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Lou YJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Mai WY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Meng HT; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Yu WJ; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Tong HY; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Jin J; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
Zhu HH; Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; Institute of Hematology, Zhejiang University, Hangzhou, China.; Zhejiang Province Key Laboratory of Hematology Oncology Diagnosis and Treatment, Hangzhou, China.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Mar 01; Vol. 96 (3), pp. 312-319. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Deletion*
Genes, p16*
Cyclin-Dependent Kinase Inhibitor p16/*deficiency
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Adolescent ; Adult ; Aged ; Allografts ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; China/epidemiology ; Combined Modality Therapy ; DNA Mutational Analysis ; DNA, Neoplasm/genetics ; Female ; Hematopoietic Stem Cell Transplantation ; High-Throughput Nucleotide Sequencing ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/mortality ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Prognosis ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Efficacy and safety of an adsorbent and anti-oxidative vaginal gel on CIN1 and 2, on high-risk HPV, and on p16/Ki-67: a randomized controlled trial.
Autorzy :
Major AL; Femina Gynecology Center, Rue Emile-Yung 1, 1205, Geneva, Switzerland. .; Department of Obstetrics and Gynecology, Cantonal Hospital, University of Fribourg, Fribourg, Switzerland. .
Dvořák V; Centrum ambulantní Gynekologie a primární péče, s.r.o., Brno, Czech Republic.
Schwarzová J; Smetanova 388, 252 64 Velké Prilepy, Prague-West, Czech Republic.
Skřivánek A; G-CENTRUM Olomouc, s.r.o., Olomouc, Czech Republic.
Malík T; Gyneko spol. s.r.o., Vsetin, Czech Republic.
Pluta M; Fakultní Nemocnice v Motole (University Hospital Motol), Onkogynekologická a kolposkopická Ambulance, Praha, Czech Republic.
Mayboroda I; Department of Obstetrics and Gynecology, University Hospital of Geneva, Geneva, Switzerland.
Grandjean EM; Phidalsa Pharma-Consultants, Petit-Lancy/Geneva, Switzerland.; Camara-Partners, Consultant, Nyon, Switzerland.
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Źródło :
Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2021 Feb; Vol. 303 (2), pp. 501-511. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Vaginal Creams, Foams, and Jellies*
Cervical Intraepithelial Neoplasia/*therapy
Cyclin-Dependent Kinase Inhibitor p16/*drug effects
Ki-67 Antigen/*drug effects
Papillomavirus Infections/*therapy
Silicon Dioxide/*administration & dosage
Sodium Selenite/*administration & dosage
Administration, Intravaginal ; Adult ; Antioxidants/administration & dosage ; Biomarkers, Tumor/analysis ; Cervical Intraepithelial Neoplasia/pathology ; Citric Acid/administration & dosage ; Colposcopy ; Cytodiagnosis ; Female ; Genes, p16 ; Humans ; Middle Aged ; Papillomavirus Infections/virology ; Pregnancy ; Treatment Outcome ; Uterine Cervical Neoplasms/prevention & control ; Vaginal Smears
Czasopismo naukowe
Tytuł :
CDKN2A Polymorphism in Melanoma Patients in Colombian Population: A Case-Control Study.
Autorzy :
Tovar-Parra JD; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Gutiérrez-Castañeda LD; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Gil-Quiñones SR; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Nova JA; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
Pulido L; Hospital Universitario-Centro Dermatológico Federico Lleras Acosta, E.S.E., DC, Bogotá, Colombia 111511, Colombia.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Oct 10; Vol. 2020, pp. 7458917. Date of Electronic Publication: 2020 Oct 10 (Print Publication: 2020).
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Melanoma/*genetics
Skin Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Colombia ; Exons ; Female ; Gene Frequency ; Genes, p16 ; Genetic Predisposition to Disease ; Genetics, Population ; Genotype ; Haplotypes ; Heterozygote ; Homozygote ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Young Adult
Czasopismo naukowe
Tytuł :
GSTs polymorphisms are associated with epigenetic silencing of CDKN2A gene in esophageal squamous cell carcinoma.
Autorzy :
Forghanifard MM; Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Aarabi A; Immunology research center, Mashhad University of Medical Sciences, Mashhad, Iran.
Nasiri Aghdam M; Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Memar B; Department of Pathology, Omeed Hospital, Mashhad University of Medical Sciences, Mashhad, 9196773117, Iran.
Hasanzadeh Khayat M; Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Dadkhah E; School of Systems Biology, George Mason University, Manassas, VA, USA.
Abbaszadegan MR; Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Sep; Vol. 27 (25), pp. 31269-31277. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Esophageal Neoplasms*
Esophageal Squamous Cell Carcinoma*
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Case-Control Studies ; Epigenesis, Genetic ; Genes, p16 ; Genetic Predisposition to Disease ; Genotype ; Glutathione S-Transferase pi/genetics ; Glutathione Transferase/genetics ; Humans ; Polymorphism, Genetic ; Risk Factors
Czasopismo naukowe
Tytuł :
Germline mutations predisposing to melanoma.
Autorzy :
Toussi A; Department of Dermatology, University of California, Davis, Sacramento, California, USA.
Mans N; Hereditary Cancer Program, Comprehensive Cancer Center, University of California, Davis, Sacramento, California, USA.
Welborn J; Hereditary Cancer Program, Comprehensive Cancer Center, University of California, Davis, Sacramento, California, USA.
Kiuru M; Department of Dermatology, University of California, Davis, Sacramento, California, USA.; Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, California, USA.
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Źródło :
Journal of cutaneous pathology [J Cutan Pathol] 2020 Jul; Vol. 47 (7), pp. 606-616. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Cyclin-Dependent Kinase Inhibitor p16/*genetics
Germ-Line Mutation/*genetics
Melanoma/*genetics
Nevus, Pigmented/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cyclin-Dependent Kinase 4/metabolism ; Genes, p16 ; Genetic Predisposition to Disease ; Humans ; Melanoma/pathology ; Microphthalmia-Associated Transcription Factor/metabolism ; Middle Aged ; Nevus, Pigmented/pathology ; Phenotype ; Receptor, Melanocortin, Type 1/metabolism ; Telomerase/metabolism ; Telomere-Binding Proteins/metabolism ; Tumor Suppressor Proteins/genetics ; Ubiquitin Thiolesterase/genetics ; Young Adult
Czasopismo naukowe

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