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Title:
Sesamin attenuates UVA-induced keratinocyte injury via inhibiting ASK-1-JNK/p38 MAPK pathways.
Authors:
Li H; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Zhu L; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Weng Z; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Fu H; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Liu J; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Mao Q; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Li W; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Ding B; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Cao Y; The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
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Source:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Jan; Vol. 23 (1), pp. 316-325. Date of Electronic Publication: 2023 Aug 06.
Publication Type:
Journal Article
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*/metabolism
p38 Mitogen-Activated Protein Kinases*/pharmacology
Matrix Metalloproteinase 9*/metabolism
Humans ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology ; Matrix Metalloproteinase 1/metabolism ; Keratinocytes/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology ; JNK Mitogen-Activated Protein Kinases/metabolism ; JNK Mitogen-Activated Protein Kinases/pharmacology ; Apoptosis ; Superoxide Dismutase/metabolism ; Ultraviolet Rays/adverse effects
Academic Journal
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Title:
BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.
Authors:
Xiao P; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Chen X; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Dong Z; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Fan W; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Chen Y; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Su J; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Wang Q; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Ma L; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
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Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2231739.
Publication Type:
Journal Article
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*/metabolism
p38 Mitogen-Activated Protein Kinases*/pharmacology
Multiple Myeloma*/drug therapy
Multiple Myeloma*/genetics
Humans ; Bortezomib/pharmacology ; Caspase 3/metabolism ; Caspase 3/pharmacology ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Proto-Oncogene Proteins/metabolism
Academic Journal
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Title:
Role of TGF-β and p38 MAPK in TSG-6 Expression in Adipose Tissue-Derived Stem Cells In Vitro and In Vivo.
Authors:
Kwon HY; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Yoon Y; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Hong JE; Department of Biomedical Laboratory Science, College of Software and Digital Healthcare Convergence, Yonsei University Mirae Campus, Wonju 26493, Republic of Korea.
Rhee KJ; Department of Biomedical Laboratory Science, College of Software and Digital Healthcare Convergence, Yonsei University Mirae Campus, Wonju 26493, Republic of Korea.
Sohn JH; Department of Convergence Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Jung PY; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Kim MY; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Baik SK; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Ryu H; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Eom YW; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
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International journal of molecular sciences [Int J Mol Sci] 2023 Dec 29; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 29.
Publication Type:
Journal Article
MeSH Terms:
Transforming Growth Factor beta*
p38 Mitogen-Activated Protein Kinases*
Pyrazoles*
Thiosemicarbazones*
Mice ; Animals ; Mice, Inbred C57BL ; Lipopolysaccharides/pharmacology ; Stem Cells ; Adipose Tissue
Academic Journal
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Title:
Ubiquinol attenuates γ-radiation induced coronary and aortic changes via PDGF/p38 MAPK/ICAM-1 related pathway.
Authors:
El-Sabbagh WA; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt.
Fadel NA; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt. noha_.
El-Hazek RM; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt.
Osman AH; Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Ramadan LA; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt.; Pharmacology and Toxicology Department, Faculty of Pharmacy, Egyptian Russian University (ERU), Cairo, Egypt.
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Source:
Scientific reports [Sci Rep] 2023 Dec 27; Vol. 13 (1), pp. 22959. Date of Electronic Publication: 2023 Dec 27.
Publication Type:
Journal Article
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*/metabolism
Mitogen-Activated Protein Kinase 14*
Rats ; Animals ; Male ; Matrix Metalloproteinase 9 ; Intercellular Adhesion Molecule-1/metabolism ; Platelet-Derived Growth Factor/pharmacology ; Endothelial Cells/metabolism ; Cell Adhesion Molecules
Academic Journal
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Title:
1,3-Dichloroadamantyl-Containing Ureas as Potential Triple Inhibitors of Soluble Epoxide Hydrolase, p38 MAPK and c-Raf.
Authors:
Gladkikh BP; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.
Danilov DV; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.
D'yachenko VS; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.; Department of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University (VSTU), Volzhsky 404121, Russia.
Butov GM; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.; Department of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University (VSTU), Volzhsky 404121, Russia.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 26; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 26.
Publication Type:
Journal Article
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*
Mitogen-Activated Protein Kinase 14*
Humans ; Epoxide Hydrolases ; Chlorine ; Ligands ; Halogens ; Chlorides
Academic Journal
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Title:
Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase.
Authors:
Hassan AHE; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Oh YI; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Lee CH; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Kim YJ; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Cho SB; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Alam MM; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Park SE; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Life and Biomedical and Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Chung KS; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Lee KT; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Life and Biomedical and Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Lee YS; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
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Source:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2217695.
Publication Type:
Journal Article
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*
Antineoplastic Agents*/pharmacology
Male ; Female ; Humans ; Phosphorylation ; Lipids
Academic Journal
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Title:
Lansoprazole protects hepatic cells against cisplatin-induced oxidative stress through the p38 MAPK/ARE/Nrf2 pathway.
Authors:
Yamagishi N; Department of Anatomy and Cell Biology, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan.
Yamamoto Y; Department of Anatomy and Cell Biology, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan.
Nishi T; Department of Anatomy and Cell Biology, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan.
Ito T; Department of Anatomy and Cell Biology, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan.
Kanai Y; Department of Anatomy and Cell Biology, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan.
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Source:
PloS one [PLoS One] 2023 Jun 29; Vol. 18 (6), pp. e0287788. Date of Electronic Publication: 2023 Jun 29 (Print Publication: 2023).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*
Mitogen-Activated Protein Kinase 14*
Animals ; Rats ; Cisplatin/adverse effects ; NF-E2-Related Factor 2/genetics ; Lansoprazole/pharmacology ; Oxidative Stress ; Hepatocytes ; Antioxidants/pharmacology
Academic Journal
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Title:
The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury.
Authors:
Liu Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.; Department of Forensic Medicine, College of Medicine, Nantong University, Nantong, 226000, China.
Sun Z; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Sun Q; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Wang L; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Wang C; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Li Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Ma C; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Shi W; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Zhang G; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.; Hebei Province Laboratory of Experimental Animal, Shijiazhuang, 050017, China.
Dong Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Zhang X; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China. .
Cong B; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China. .; Hainan Tropical Forensic Medicine Academician Workstation, Haikou, 571199, China. .
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Source:
Lipids in health and disease [Lipids Health Dis] 2024 Mar 02; Vol. 23 (1), pp. 68. Date of Electronic Publication: 2024 Mar 02.
Publication Type:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases*/metabolism
Tandem Mass Spectrometry*
Rats ; Animals ; Chromatography, Liquid ; Ceramides/metabolism ; Hepatocytes/metabolism ; Liver/metabolism ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism ; Apoptosis ; Sphingosine N-Acyltransferase/genetics ; Sphingosine N-Acyltransferase/metabolism
Academic Journal
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Title:
Vitamin D 3 inhibits p38 MAPK and senescence-associated inflammatory mediator secretion by senescent fibroblasts that impacts immune responses during ageing.
Authors:
Sayegh S; Division of Medicine, University College London, London, UK.
Fantecelle CH; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Laphanuwat P; Division of Medicine, University College London, London, UK.
Subramanian P; Division of Medicine, University College London, London, UK.
Rustin MHA; Department of Dermatology, Royal Free Hospital, London, UK.
Gomes DCO; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitoria, Brazil.
Akbar AN; Division of Medicine, University College London, London, UK.
Chambers ES; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK.
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Source:
Aging cell [Aging Cell] 2024 Apr; Vol. 23 (4), pp. e14093. Date of Electronic Publication: 2024 Jan 29.
Publication Type:
Journal Article
MeSH Terms:
Cellular Senescence*/genetics
Cholecalciferol*/pharmacology
Cholecalciferol*/metabolism
Adult ; Humans ; Aged ; p38 Mitogen-Activated Protein Kinases/metabolism ; Aging ; Fibroblasts/metabolism ; Inflammation Mediators/metabolism ; Immunity
Academic Journal
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Title:
Brain-Derived Neurotrophic Factor (BDNF) Enhances Osteogenesis and May Improve Bone Microarchitecture in an Ovariectomized Rat Model.
Authors:
Park EJ; Department of Orthopedic Surgery, Kyungpook National University Hospital, College of Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Truong VL; Food and Bio-Industry Research Institute, School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Jeong WS; Food and Bio-Industry Research Institute, School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Min WK; Department of Orthopedic Surgery, Kyungpook National University Hospital, College of Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
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Source:
Cells [Cells] 2024 Mar 15; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 15.
Publication Type:
Journal Article
MeSH Terms:
Osteogenesis*
Brain-Derived Neurotrophic Factor*/pharmacology
Rats ; Animals ; Calcium/pharmacology ; Rats, Sprague-Dawley ; p38 Mitogen-Activated Protein Kinases/metabolism
Academic Journal
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Title:
Edgeworthia gardneri (Wall.) Meisn. Ethanolic Extract Attenuates Endothelial Activation and Alleviates Cardiac Ischemia-Reperfusion Injury.
Authors:
Lang X; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Zhong C; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.; Department of Cardiovascular Sciences, Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Su L; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Qin M; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Xie Y; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Shan D; Department of Cardiovascular Sciences, Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Cui Y; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.; Department of Cardiovascular Sciences, Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Shi M; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Li M; Center for Traditional Chinese Medicine Resources and Ethnic Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Quan H; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Qiu L; Center for Translational Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Zhong G; Center for Traditional Chinese Medicine Resources and Ethnic Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Yu J; Department of Cardiovascular Sciences, Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
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Molecules (Basel, Switzerland) [Molecules] 2024 Feb 29; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 29.
Publication Type:
Journal Article
MeSH Terms:
Myocardial Reperfusion Injury*/drug therapy
Thymelaeaceae*/metabolism
Rats ; Animals ; Endothelial Cells/metabolism ; NF-kappa B/metabolism ; Inflammation/drug therapy ; Plant Extracts/pharmacology ; Endothelium/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Academic Journal
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Title:
Inhibitory Effects of Eicosapentaenoic Acid on Vascular Endothelial Growth Factor-Induced Monocyte Chemoattractant Protein-1, Interleukin-6, and Interleukin-8 in Human Vascular Endothelial Cells.
Authors:
Takenoshita Y; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Tokito A; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Jougasaki M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
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International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.
Publication Type:
Journal Article
MeSH Terms:
Chemokine CCL2*/metabolism
Interleukin-6*/metabolism
Humans ; Interleukin-8/metabolism ; NF-kappa B/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Eicosapentaenoic Acid/pharmacology ; Human Umbilical Vein Endothelial Cells/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Academic Journal
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Title:
TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway.
Authors:
Tian Y; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Xiao X; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Liu W; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Cheng S; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Qian N; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Wang L; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Liu Y; School of Pediatrics, Guizhou Medical University, Guiyang City, China.; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China.
Ai R; School of Pediatrics, Guizhou Medical University, Guiyang City, China. .; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China. .
Zhu X; School of Pediatrics, Guizhou Medical University, Guiyang City, China. .; Department of Pediatrics, The Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, 550004, Guiyang City, China. .
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Molecular brain [Mol Brain] 2024 Feb 26; Vol. 17 (1), pp. 12. Date of Electronic Publication: 2024 Feb 26.
Publication Type:
Journal Article
MeSH Terms:
Autism Spectrum Disorder*/metabolism
Animals ; Female ; Pregnancy ; Rats ; Disease Models, Animal ; Microglia/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism ; Signal Transduction ; Valproic Acid/pharmacology
Academic Journal
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Title:
Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression.
Authors:
Deng Y; Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Hou Z; Center for Mitochondrial Biology and Medicine & Douglas C. Wallace Institute for Mitochondrial and Epigenetic Information Sciences, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Li Y; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yi M; Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Wu Y; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zheng Y; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yang F; Center for Mitochondrial Biology and Medicine & Douglas C. Wallace Institute for Mitochondrial and Epigenetic Information Sciences, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zhong G; Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Hao Q; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhai Z; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang M; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ma X; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Kang H; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ji F; Department of Infectious Diseases, The Second Affiliated Hospital of Xian Jiaotong University, Xi'an, China.
Dong C; Department of Pathology and Pathophysiology, Department of Colorectal Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, Ministry of Education, Zhejiang University School of Medicine, Hangzhou, China. .; Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou, 310058, China. .
Liu H; Center for Mitochondrial Biology and Medicine & Douglas C. Wallace Institute for Mitochondrial and Epigenetic Information Sciences, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China. .
Dai Z; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. .; Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. .
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Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 12; Vol. 22 (1), pp. 115. Date of Electronic Publication: 2024 Feb 12.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/metabolism
Triple Negative Breast Neoplasms*/pathology
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Dasatinib/pharmacology ; Mice, Nude ; p38 Mitogen-Activated Protein Kinases/metabolism ; Peptides/pharmacology ; Protein Kinase C-delta/metabolism ; src-Family Kinases
Academic Journal
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Title:
MKK4 Inhibitors-Recent Development Status and Therapeutic Potential.
Authors:
Katzengruber L; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Faculty of Sciences, University of Tuebingen, 72076 Tübingen, Germany.
Sander P; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Faculty of Sciences, University of Tuebingen, 72076 Tübingen, Germany.
Laufer S; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Faculty of Sciences, University of Tuebingen, 72076 Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided & Functionally Instructed Tumor Therapies', Eberhard Karls Universität Tübingen, 72076 Tübingen, Germany.; Tübingen Center for Academic Drug Discovery, Auf der Morgenstelle 8, 72076 Tübingen, Germany.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 19; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 19.
Publication Type:
Journal Article; Review
MeSH Terms:
Ovarian Neoplasms*/pathology
p38 Mitogen-Activated Protein Kinases*/metabolism
Female ; Humans ; Male ; JNK Mitogen-Activated Protein Kinases/metabolism ; MAP Kinase Kinase 4/metabolism ; Phosphorylation
Academic Journal
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Title:
Ionizing Radiation Selectively Increases CXC Ligand 10 Level via the DNA-Damage-Induced p38 MAPK-STAT1 Pathway in Murine J774A.1 Macrophages.
Authors:
Seo YN; Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan 46033, Republic of Korea.; Department of Microbiology and Immunology, College of Medicine, Inge University, Busan 47392, Republic of Korea.
Baik JS; Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan 46033, Republic of Korea.; Department of Medicinal Biotechnology, College of Health Sciences, Dong-A University, Busan 49315, Republic of Korea.
Lee SM; Department of Veterinary Medicine, College of Veterinary Medicine, Kyoung Pook National University, Daegu 41566, Republic of Korea.
Lee JE; Department of Veterinary Medicine, College of Veterinary Medicine, Kyoung Pook National University, Daegu 41566, Republic of Korea.
Ahn HR; Department of Veterinary Medicine, College of Veterinary Medicine, Kyoung Pook National University, Daegu 41566, Republic of Korea.
Lim MS; Department of Veterinary Medicine, College of Veterinary Medicine, Kyoung Pook National University, Daegu 41566, Republic of Korea.
Park MT; Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan 46033, Republic of Korea.
Kim SD; Department of Veterinary Medicine, College of Veterinary Medicine, Kyoung Pook National University, Daegu 41566, Republic of Korea.
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Source:
Cells [Cells] 2023 Mar 25; Vol. 12 (7). Date of Electronic Publication: 2023 Mar 25.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*/metabolism
Endothelial Cells*/metabolism
Animals ; Mice ; Ligands ; Macrophages/metabolism ; Radiation, Ionizing ; DNA ; STAT1 Transcription Factor/metabolism
Academic Journal
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Title:
Computational and Functional Analysis of Structural Features in the ZAKα Kinase.
Authors:
Johansen VBI; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Snieckute G; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Vind AC; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Blasius M; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Bekker-Jensen S; Center for Healthy Aging, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
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Source:
Cells [Cells] 2023 Mar 22; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 22.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ribosomes*/metabolism
p38 Mitogen-Activated Protein Kinases*/metabolism
Academic Journal
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Title:
MAPK Pathways in Ocular Pathophysiology: Potential Therapeutic Drugs and Challenges.
Authors:
Moustardas P; Division of Ophthalmology, Department of Biomedical and Clinical Sciences, Linköping University, 58185 Linköping, Sweden.
Aberdam D; INSERM U1138, Centre des Cordeliers, 75270 Paris, France.; Université de Paris Cité, 75014 Paris, France.
Lagali N; Division of Ophthalmology, Department of Biomedical and Clinical Sciences, Linköping University, 58185 Linköping, Sweden.; Department of Ophthalmology, Sørlandet Hospital Arendal, 4838 Arendal, Norway.
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Source:
Cells [Cells] 2023 Feb 14; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 14.
Publication Type:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitogen-Activated Protein Kinases*/metabolism
p38 Mitogen-Activated Protein Kinases*/metabolism
Signal Transduction ; Phosphorylation ; MAP Kinase Signaling System/physiology
Academic Journal
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Title:
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
Authors:
He Y; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Luo M; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Lei S; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Zeng Z; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Chen T; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Wu Y; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Wang D; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Wang L; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
Wang L; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Disease, Department of Physiology, College of Basic Medicine, Guizhou Medical University, Guiyang 550025, China.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 12; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 12.
Publication Type:
Journal Article
MeSH Terms:
p38 Mitogen-Activated Protein Kinases*/metabolism
Neuroblastoma*/drug therapy
Animals ; Mice ; Humans ; Cell Proliferation ; Mice, Nude ; Molecular Docking Simulation ; Cell Line, Tumor ; Apoptosis ; G1 Phase
Academic Journal
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Title:
Glycyrrhizin regulates the HMGB1/P38MAPK signalling pathway in status epilepticus.
Authors:
Luo Z; Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China.
Xu M; Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China.
Zhang L; Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China.
Zhang H; Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China.
Xu Z; Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China.
Xu Z; Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China.
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Source:
Molecular medicine reports [Mol Med Rep] 2023 Feb; Vol. 27 (2). Date of Electronic Publication: 2023 Jan 12.
Publication Type:
Journal Article
MeSH Terms:
Glycyrrhizic Acid*/pharmacology
Glycyrrhizic Acid*/therapeutic use
HMGB1 Protein*/metabolism
Status Epilepticus*/drug therapy
p38 Mitogen-Activated Protein Kinases*/metabolism
Animals ; Rats ; Hippocampus/drug effects ; Hippocampus/metabolism ; Rats, Sprague-Dawley ; Signal Transduction/drug effects
Academic Journal
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Showing 1-20 from 3968 results

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