Temat: "phosphorylcholine" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Hemocompatibility of β-Cyclodextrin-Modified (Methacryloyloxy)ethyl Phosphorylcholine Coated Magnetic Nanoparticles.
Autorzy:: Li S; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 1H9, Canada.
Sharaf MG; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 1H9, Canada.
Rowe EM; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z7, Canada.
Serrano K; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z7, Canada.
Devine DV; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z7, Canada.
Unsworth LD; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 1H9, Canada.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Jul 25; Vol. 13 (8). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phosphorylcholine*
Magnetite Nanoparticles*
Adsorption ; Antithrombin III ; Blood Coagulation

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Skocz do pozycji: 2.

Tytuł:: Different choline supplement metabolism in adults using deuterium labelling.
Autorzy:: Böckmann KA; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany. .
Franz AR; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany.; Center for Pediatric Clinical Studies, Eberhard Karls University, Tübingen, Germany.
Shunova A; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany.
Minarski M; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany.
Wiechers C; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany.
Poets CF; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany.
Bernhard W; Department of Neonatology, Faculty of Medicine, Eberhard Karls University, Calwer Straße 7, 72076, Tübingen, Germany.; Pokaż więcej
Źródło:: European journal of nutrition [Eur J Nutr] 2023 Jun; Vol. 62 (4), pp. 1795-1807. Date of Electronic Publication: 2023 Feb 25.
Typ publikacji:: Journal Article; Randomized Controlled Trial
MeSH Terms:: Betaine*
Phosphorylcholine*
Adult ; Humans ; Infant ; Infant, Newborn ; Male ; Choline ; Cross-Over Studies ; Deuterium ; Fatty Acids ; Infant, Premature ; Phosphatidylcholines ; Prospective Studies

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Skocz do pozycji: 3.

Tytuł:: Chitosan nanoparticles improve the effectivity of miltefosine against Acanthamoeba.
Autorzy:: Latifi A; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Esmaeili F; Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohebali M; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.; Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran.
Yasami-Khiabani S; Department of Parasitology, Pasteur Institute of Iran, Tehran, Iran.
Rezaeian M; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Soleimani M; Department of Ocular Trauma and Emergency, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Kazemirad E; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Amani A; Natural products and medicinal plants Research center, North Khorasan University of Medical Sciences, Bojnurd, Iran.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Mar 25; Vol. 18 (3), pp. e0011976. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Chitosan*/pharmacology
Acanthamoeba*
Nanoparticles*
Phosphorylcholine/*analogs & derivatives
Animals ; Rabbits ; Drug Carriers

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Skocz do pozycji: 4.

Tytuł:: Vascular Endothelial Cell-Derived Exosomal Sphingosylphosphorylcholine Attenuates Myocardial Ischemia-Reperfusion Injury through NR4A2-Mediated Mitophagy.
Autorzy:: Yu Y; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China.
Li Z; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China.
Cai Y; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China.
Guo J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China.
Lin Y; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China.
Zhao J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Qingdao 266237, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 14; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Myocardial Reperfusion Injury*/metabolism
Myocardial Infarction*/drug therapy
Myocardial Infarction*/metabolism
Exosomes*/metabolism
Phosphorylcholine/*analogs & derivatives
Sphingosine/*analogs & derivatives
Mice ; Animals ; Mitophagy ; Myocytes, Cardiac/metabolism ; Endothelial Cells/metabolism ; Apoptosis

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Skocz do pozycji: 5.

Tytuł:: Plasma metabolomic profile in orthostatic intolerance children with high levels of plasma homocysteine.
Autorzy:: Li Y; Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China.
Bai B; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China.
Wang H; Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China.
Wu H; Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China.
Deng Y; Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China.
Shen C; Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China.
Zhang Q; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China. .
Shi L; Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, No 2 Yabao Road, Beijing, Chaoyang District, 100020, China. .; Pokaż więcej
Źródło:: Italian journal of pediatrics [Ital J Pediatr] 2024 Mar 14; Vol. 50 (1), pp. 52. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Orthostatic Intolerance*
Syncope, Vasovagal*
Phosphorylcholine/*analogs & derivatives
Glycerol/*analogs & derivatives
Adolescent ; Child ; Humans ; Glutamic Acid ; Glycerylphosphorylcholine ; Sphingomyelins ; Choline ; Homocysteine

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Skocz do pozycji: 6.

Tytuł:: Disseminated Leishmaniasis, a Severe Form of Leishmania braziliensis Infection.
Autorzy:: Machado PRL
Lago A
Cardoso TM
Magalhaes A
Carvalho LP
Lago T
Carvalho AM
Costa R
Carvalho EM; Pokaż więcej
Źródło:: Emerging infectious diseases [Emerg Infect Dis] 2024 Mar; Vol. 30 (3), pp. 510-518.
Typ publikacji:: Journal Article
MeSH Terms:: Leishmania braziliensis*
Leishmaniasis, Cutaneous*/diagnosis
Leishmaniasis, Cutaneous*/drug therapy
Leishmania*
Phosphorylcholine/*analogs & derivatives
Humans ; Meglumine Antimoniate/therapeutic use

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Skocz do pozycji: 7.

Tytuł:: Protein-liposome interactions: the impact of surface charge and fluidisation effect on protein binding.
Autorzy:: Triantafyllopoulou E; Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Pippa N; Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Demetzos C; Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.; Pokaż więcej
Źródło:: Journal of liposome research [J Liposome Res] 2023 Mar; Vol. 33 (1), pp. 77-88. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:: Journal Article
MeSH Terms:: Liposomes*/chemistry
Phosphorylcholine*
Protein Binding ; Serum Albumin, Bovine ; Gene Transfer Techniques

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Skocz do pozycji: 8.

Tytuł:: Quantitative Analysis of the Human Semen Phosphorometabolome by P-NMR.
Autorzy:: Serrano R; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Research Institute INBIO G+C, University of Extremadura, 10003 Caceres, Spain.
Martin-Hidalgo D; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Research Institute INBIO G+C, University of Extremadura, 10003 Caceres, Spain.
Bilbao J; Precision Medicine and Metabolism Laboratory, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain.
Bernardo-Seisdedos G; Precision Medicine and Metabolism Laboratory, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain.; Department of Medicine, Faculty of Health Sciences, University of Deusto, 48007 Bilbao, Spain.
Millet O; Precision Medicine and Metabolism Laboratory, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain.; CIBERehd, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Garcia-Marin LJ; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Research Institute INBIO G+C, University of Extremadura, 10003 Caceres, Spain.
Bragado MJ; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Research Institute INBIO G+C, University of Extremadura, 10003 Caceres, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 30; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:: Journal Article
MeSH Terms:: Semen*/metabolism
Asthenozoospermia*/metabolism
Organophosphates*
Humans ; Male ; Phosphorylcholine/metabolism ; Sperm Motility ; Spermatozoa/metabolism ; Phosphorus/metabolism ; Semen Analysis

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Skocz do pozycji: 9.

Tytuł:: Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation.
Autorzy:: Zhang Y; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. .
Li N; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan.
Kobayashi S; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 22; Vol. 22 (1), pp. 58. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:: Muscle, Smooth, Vascular*
Paxillin*
rho-Associated Kinases*
Animals ; Humans ; Mice ; Actins ; Mice, Knockout ; Myosin Light Chains ; Phosphorylcholine/analogs & derivatives ; Sphingosine/analogs & derivatives

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Skocz do pozycji: 10.

Tytuł:: Metabolomic Insight into Implications of Induction Chemotherapy Followed by Concomitant Chemoradiotherapy in Locally Advanced Head and Neck Cancer.
Autorzy:: Boguszewicz Ł; Department of Medical Physics, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Bieleń A; 1st Radiation and Clinical Oncology Department, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Ciszek M; Department of Medical Physics, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Skorupa A; Department of Medical Physics, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Mrochem-Kwarciak J; Analytics and Clinical Biochemistry Department, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Składowski K; 1st Radiation and Clinical Oncology Department, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Sokół M; Department of Medical Physics, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 22; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 22.
Typ publikacji:: Journal Article
MeSH Terms:: Induction Chemotherapy*
Head and Neck Neoplasms*/therapy
Humans ; Squamous Cell Carcinoma of Head and Neck/therapy ; Phosphorylcholine ; Chemoradiotherapy/adverse effects ; Betaine ; Serine ; Tyrosine ; Lipids

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Skocz do pozycji: 11.

Tytuł:: Spiro heterocycles bearing piperidine moiety as potential scaffold for antileishmanial activity: synthesis, biological evaluation, and in silico studies.
Autorzy:: Mohamed MAA; Chemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
Kadry AM; Chemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
Bekhit SA; High Institute of Public Health, Alexandria University, Alexandria, Egypt.
Abourehab MAS; Department of Pharmaceutics, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Amagase K; Laboratory of Pharmacology & Pharmacotherapeutics, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Japan.
Ibrahim TM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh, Egypt.
El-Saghier AMM; Chemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
Bekhit AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; Allied Health Department, College of Health and Sport Sciences, University of Bahrain, Sakhir, Kingdom of Bahrain.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 330-342.
Typ publikacji:: Journal Article
MeSH Terms:: Antiprotozoal Agents*/pharmacology
Chlorocebus aethiops ; Animals ; Vero Cells ; Phosphorylcholine ; Piperidines/pharmacology

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Skocz do pozycji: 12.

Tytuł:: Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study.
Autorzy:: Younis BM; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Mudawi Musa A; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Monnerat S; Drugs for Neglected Diseases initiative, Geneva, Switzerland.
Abdelrahim Saeed M; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Awad Gasim Khalil E; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Elbashir Ahmed A; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Ahmed Ali M; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Noureldin A; Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Muthoni Ouattara G; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Nyakaya GM; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Teshome S; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Omollo T; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Ochieng M; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Egondi T; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Mmbone M; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Chu WY; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Dorlo TPC; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Zijlstra EE; Drugs for Neglected Diseases initiative, Geneva, Switzerland.
Wasunna M; Drugs for Neglected Diseases initiative, Nairobi, Kenya.
Alvar J; Drugs for Neglected Diseases initiative, Geneva, Switzerland.
Alves F; Drugs for Neglected Diseases initiative, Geneva, Switzerland.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Nov 21; Vol. 17 (11), pp. e0011780. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2023).
Typ publikacji:: Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article
MeSH Terms:: Leishmaniasis, Visceral*/drug therapy
Antiprotozoal Agents*/adverse effects
Leishmaniasis, Cutaneous*/drug therapy
Humans ; Child ; Paromomycin/adverse effects ; Phosphorylcholine/adverse effects ; Treatment Outcome

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Skocz do pozycji: 13.

Tytuł:: Increased Leishmania infantum resistance to miltefosine and amphotericin B after treatment of a dog with miltefosine and allopurinol.
Autorzy:: Gonçalves G; Cell Biology Laboratory, Carlos Chagas Institute, Oswaldo Cruz Foundation (FIOCRUZ), Curitiba, Paraná, 81310-020, Brazil. .
Campos MP; Cell Biology Laboratory, Carlos Chagas Institute, Oswaldo Cruz Foundation (FIOCRUZ), Curitiba, Paraná, 81310-020, Brazil.
Gonçalves AS; Private Practice, Campo Grande, Brazil.
Medeiros LCS; Cell Biology Laboratory, Carlos Chagas Institute, Oswaldo Cruz Foundation (FIOCRUZ), Curitiba, Paraná, 81310-020, Brazil.
Figueiredo FB; Cell Biology Laboratory, Carlos Chagas Institute, Oswaldo Cruz Foundation (FIOCRUZ), Curitiba, Paraná, 81310-020, Brazil.; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2021 Dec 09; Vol. 14 (1), pp. 599. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji:: Journal Article
MeSH Terms:: Amphotericin B/*pharmacology
Antiprotozoal Agents/*pharmacology
Dog Diseases/*parasitology
Leishmania infantum/*drug effects
Leishmaniasis, Visceral/*parasitology
Phosphorylcholine/*analogs & derivatives
Allopurinol/therapeutic use ; Animals ; Antiprotozoal Agents/therapeutic use ; Dog Diseases/drug therapy ; Dogs ; Drug Resistance ; Female ; Leishmaniasis, Visceral/drug therapy ; Meglumine Antimoniate/therapeutic use ; Phosphorylcholine/pharmacology ; Phosphorylcholine/therapeutic use

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Skocz do pozycji: 14.

Tytuł:: Mga Spn is a negative regulator of capsule and phosphorylcholine biosynthesis and influences the virulence of Streptococcus pneumoniae D39.
Autorzy:: Xiao S; Department of Medicine Laboratory, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders; and Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.
Suo W; Department of Medicine Laboratory, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders; and Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.
Zhang J; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, People's Republic of China.
Zhang X; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, People's Republic of China.
Yin Y; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, People's Republic of China.
Guo X; Department of Medicine Laboratory, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders; and Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.
Zheng Y; Department of Medicine Laboratory, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders; and Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.; Pokaż więcej
Źródło:: Virulence [Virulence] 2021 Dec; Vol. 12 (1), pp. 2366-2381.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phosphorylcholine*/metabolism
Streptococcus pneumoniae*/genetics
Streptococcus pneumoniae*/pathogenicity
Transcription Factors*/metabolism
Virulence*
Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Virulence Factors/genetics

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Skocz do pozycji: 15.

Tytuł:: Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules.
Autorzy:: El-Sheridy NA; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; European Egyptian Pharmaceutical Industries, Alexandria, Egypt.
El-Moslemany RM; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Ramadan AA; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Helmy MW; Department of Pharmacology, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt.
El-Khordagui LK; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; Pokaż więcej
Źródło:: Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 906-919.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Itraconazole/*pharmacology
Nanocapsules/*chemistry
Phosphorylcholine/*analogs & derivatives
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacokinetics ; Apoptosis/drug effects ; Cell Survival/drug effects ; Chemistry, Pharmaceutical ; Drug Carriers/chemistry ; Drug Combinations ; Drug Liberation ; Female ; Hedgehog Proteins/drug effects ; Humans ; Itraconazole/administration & dosage ; Itraconazole/pharmacokinetics ; MCF-7 Cells ; Mice ; Mice, Inbred BALB C ; Neovascularization, Pathologic/drug therapy ; Particle Size ; Phosphorylcholine/administration & dosage ; Phosphorylcholine/pharmacokinetics ; Phosphorylcholine/pharmacology ; Random Allocation

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Skocz do pozycji: 16.

Tytuł:: Lipid raft-disrupting miltefosine preferentially induces the death of colorectal cancer stem-like cells.
Autorzy:: Park SY; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.; Cell Logistics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Kim JH; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Choi JH; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Lee CJ; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Lee WJ; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Park S; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Park ZY; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
Baek JH; Division of Colon and Rectal Surgery, Department of Surgery, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.
Nam JS; School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.; Cell Logistics Research Center, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2021 Nov; Vol. 11 (11), pp. e552.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Colorectal Neoplasms/*drug therapy
Membrane Microdomains/*drug effects
Phosphorylcholine/*analogs & derivatives
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Proliferation/drug effects ; Colorectal Neoplasms/physiopathology ; Disease Models, Animal ; Mice ; Phosphorylcholine/pharmacology ; Phosphorylcholine/therapeutic use

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Skocz do pozycji: 17.

Tytuł:: Cell behaviors within a confined adhesive area fabricated using novel micropatterning methods.
Autorzy:: Nakatoh T; Graduate School of Sciences and Technology for Innovation, Yamaguchi University, Yamaguchi, Japan.
Osaki T; Shoyo Sangyo Co., Ltd, Chuo-ku, Osaka, Japan.
Tanimoto S; Graduate School of Sciences and Technology for Innovation, Yamaguchi University, Yamaguchi, Japan.
Jahan MGS; Graduate School of Sciences and Technology for Innovation, Yamaguchi University, Yamaguchi, Japan.; Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi, Bangladesh.
Kawakami T; Shoyo Sangyo Co., Ltd, Chuo-ku, Osaka, Japan.
Chihara K; Shoyo Sangyo Co., Ltd, Chuo-ku, Osaka, Japan.
Sakai N; Graduate School of Sciences and Technology for Innovation, Yamaguchi University, Yamaguchi, Japan.
Yumura S; Graduate School of Sciences and Technology for Innovation, Yamaguchi University, Yamaguchi, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jan 14; Vol. 17 (1), pp. e0262632. Date of Electronic Publication: 2022 Jan 14 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Cell Adhesion/*physiology
Cell Engineering/*methods
Methacrylates/*chemistry
Phosphorylcholine/*analogs & derivatives
Adhesiveness ; Adhesives/chemistry ; Cell Adhesion/genetics ; Dictyostelium/drug effects ; Dictyostelium/growth & development ; Dictyostelium/metabolism ; Lipids/chemistry ; Phosphorylcholine/chemistry ; Plastics/chemistry ; Surface Properties ; Tissue Engineering/methods

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Skocz do pozycji: 18.

Tytuł:: Multi-Step Synthesis of Miltefosine: Integration of Flow Chemistry with Continuous Mechanochemistry.
Autorzy:: Patil NB; Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune, 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Atapalkar RS; Chemical Engineering & Process Development, CSIR-National Chemical Laboratory, Pune, 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Chavan SP; Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune, 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Kulkarni AA; Chemical Engineering & Process Development, CSIR-National Chemical Laboratory, Pune, 411008, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.; Pokaż więcej
Źródło:: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Dec 15; Vol. 27 (70), pp. 17695-17699. Date of Electronic Publication: 2021 Oct 25.
Typ publikacji:: Journal Article
MeSH Terms:: Phosphorylcholine*/analogs & derivatives
Chemistry Techniques, Synthetic ; Humans

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Skocz do pozycji: 19.

Tytuł:: Systemic Miltefosine as an Adjunct Treatment of Progressive Acanthamoeba Keratitis.
Autorzy:: Naranjo A; Anne Bates Leach Eye Clinics, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Martinez JD; Anne Bates Leach Eye Clinics, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Miller D; Ocular Microbiology Laboratory, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Tonk R; Anne Bates Leach Eye Clinics, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Amescua G; Anne Bates Leach Eye Clinics, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.; Pokaż więcej
Źródło:: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2021 Nov 17; Vol. 29 (7-8), pp. 1576-1584. Date of Electronic Publication: 2020 May 29.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Acanthamoeba Keratitis/*drug therapy
Antiprotozoal Agents/*therapeutic use
Phosphorylcholine/*analogs & derivatives
Acanthamoeba Keratitis/diagnosis ; Acanthamoeba Keratitis/etiology ; Administration, Oral ; Adolescent ; Adult ; Contact Lenses/adverse effects ; Female ; Follow-Up Studies ; Humans ; Keratoplasty, Penetrating ; Middle Aged ; Phosphorylcholine/therapeutic use ; Retrospective Studies ; Risk Factors ; Visual Acuity/physiology ; Young Adult

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Skocz do pozycji: 20.

Tytuł:: Miltefosine for the treatment of cutaneous leishmaniasis-A pilot study from Ethiopia.
Autorzy:: van Henten S; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Tesfaye AB; Department of Dermatology, University of Gondar Hospital, Gondar, Ethiopia.
Abdela SG; Department of Internal Medicine, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Tilahun F; Boru Meda Hospital, Dessie, Ethiopia.
Fikre H; Leishmania Research and Treatment Center, University of Gondar Hospital, Gondar, Ethiopia.
Buyze J; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Kassa M; Leishmania Research and Treatment Center, University of Gondar Hospital, Gondar, Ethiopia.
Cnops L; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Pareyn M; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Mohammed R; Leishmania Research and Treatment Center, University of Gondar Hospital, Gondar, Ethiopia.
Vogt F; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; National Centre for Epidemiology and Population Health, Research School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.; The Kirby Institute, University of New South Wales, Sydney, Australia.
Diro E; Leishmania Research and Treatment Center, University of Gondar Hospital, Gondar, Ethiopia.
van Griensven J; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 May 28; Vol. 15 (5), pp. e0009460. Date of Electronic Publication: 2021 May 28 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiprotozoal Agents/*therapeutic use
Leishmaniasis, Cutaneous/*drug therapy
Phosphorylcholine/*analogs & derivatives
Administration, Oral ; Adolescent ; Adult ; Antiprotozoal Agents/administration & dosage ; Antiprotozoal Agents/adverse effects ; Cohort Studies ; Ethiopia ; Female ; Humans ; Leishmania/drug effects ; Male ; Phosphorylcholine/administration & dosage ; Phosphorylcholine/adverse effects ; Phosphorylcholine/therapeutic use ; Pilot Projects ; Treatment Adherence and Compliance/statistics & numerical data ; Treatment Outcome

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