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Tytuł :
Main bioactive phenolic compounds in marine algae and their mechanisms of action supporting potential health benefits.
Autorzy :
Jimenez-Lopez C; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolonia, 5300-253 Bragança, Portugal.
Pereira AG; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolonia, 5300-253 Bragança, Portugal.
Lourenço-Lopes C; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain.
Garcia-Oliveira P; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolonia, 5300-253 Bragança, Portugal.
Cassani L; Research Group of Food Engineering, Faculty of Engineering, National University of Mar del Plata, RA7600 Mar del Plata, Argentina.
Fraga-Corral M; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolonia, 5300-253 Bragança, Portugal.
Prieto MA; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain. Electronic address: .
Simal-Gandara J; Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Mar 30; Vol. 341 (Pt 2), pp. 128262. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Antioxidants/*pharmacology
Phenols/*pharmacology
Plant Extracts/*chemistry
Seaweed/*chemistry
Anti-Infective Agents/chemistry ; Anti-Infective Agents/isolation & purification ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; Phenols/chemistry ; Phenols/isolation & purification ; Seawater ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Molecular mechanisms underlying the anticancer activities of licorice flavonoids.
Autorzy :
Zhang Z; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yang L; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Hou J; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Tian S; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Liu Y; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113635. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Glycyrrhiza*/chemistry
Glycyrrhiza*/toxicity
Antineoplastic Agents, Phytogenic/*pharmacology
Flavonoids/*pharmacology
Neoplasms/*drug therapy
Plant Extracts/*pharmacology
Signal Transduction/*drug effects
Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/toxicity ; Apoptosis/drug effects ; Apoptosis Regulatory Proteins/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Cycle Proteins/metabolism ; Cell Proliferation/drug effects ; Flavonoids/isolation & purification ; Flavonoids/toxicity ; Humans ; Neoplasms/metabolism ; Neoplasms/pathology ; Plant Extracts/isolation & purification ; Plant Extracts/toxicity
Czasopismo naukowe
Tytuł :
Panduratins Q-Y, dimeric metabolites from Boesenbergia rotunda and their antiausterity activities against the PANC-1 human pancreatic cancer cell line.
Autorzy :
Nguyen MTT; Faculty of Chemistry, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Cancer Research Laboratory, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Vietnam National University, Quarter 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Viet Nam.
Nguyen HX; Faculty of Chemistry, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Vietnam National University, Quarter 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Viet Nam.
Dang PH; Faculty of Chemistry, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Vietnam National University, Quarter 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Viet Nam.
Le TH; Faculty of Chemistry, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Vietnam National University, Quarter 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Viet Nam.
Do TNV; Faculty of Chemistry, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Vietnam National University, Quarter 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Viet Nam.
Omar AM; Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
Awale S; Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
Nguyen NT; Faculty of Chemistry, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Cancer Research Laboratory, University of Science, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam; Vietnam National University, Quarter 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Viet Nam. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2021 Mar; Vol. 183, pp. 112646. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic*/pharmacology
Antineoplastic Agents, Phytogenic*/therapeutic use
Pancreatic Neoplasms*/drug therapy
Zingiberaceae*
Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Humans ; Rhizome
Czasopismo naukowe
Tytuł :
Phytochemicals and biological properties of Annona coriacea Mart. (Annonaceae): A systematic review from 1971 to 2020.
Autorzy :
Rocha GNDSAO; Center for Studies and Research of Medicinal Plants (NEPLAME), Federal University of San Francisco Valley, 56, 304-205, Petrolina, PE, Brazil.
Dutra LM; Center for Studies and Research of Medicinal Plants (NEPLAME), Federal University of San Francisco Valley, 56, 304-205, Petrolina, PE, Brazil.
Lorenzo VP; Federal Institute of Education, Science and Technology of Sertão Pernambucano, 56, 316-686, Petrolina, PE, Brazil.
Almeida JRGDS; Center for Studies and Research of Medicinal Plants (NEPLAME), Federal University of San Francisco Valley, 56, 304-205, Petrolina, PE, Brazil. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Feb 25; Vol. 336, pp. 109390. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Annonaceae/*chemistry
Anti-Inflammatory Agents/*pharmacology
Anti-Ulcer Agents/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Insecticides/*pharmacology
Phytochemicals/*pharmacology
Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Anti-Ulcer Agents/chemistry ; Anti-Ulcer Agents/isolation & purification ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Humans ; Insecticides/chemistry ; Insecticides/isolation & purification ; Molecular Conformation ; Phytochemicals/chemistry ; Phytochemicals/isolation & purification
Czasopismo naukowe
Tytuł :
Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines.
Autorzy :
Adham AN; Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Kurdistan Region, Iraq; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128, Mainz, Germany.
Naqishbandi AM; Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Kurdistan Region, Iraq. Electronic address: .
Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128, Mainz, Germany.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Feb 10; Vol. 266, pp. 113458. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Fumaria/*chemistry
Leukemia/*drug therapy
Multiple Myeloma/*drug therapy
Plant Extracts/*pharmacology
Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Autophagy/drug effects ; Cell Line, Tumor ; Humans ; Inhibitory Concentration 50 ; Leukemia/pathology ; Membrane Potential, Mitochondrial/drug effects ; Multiple Myeloma/pathology ; Plant Extracts/administration & dosage ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Intracellular Paclitaxel Delivery Facilitated by a Dual-Functional CPP with a Hydrophobic Hairpin Tail.
Autorzy :
Wei Y; School of Life Science and Technology, Nanyang Normal University, Nanyang, Henan Province 473061, P.R. China.; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P.R. China.
Zhang M; Department of Oncology, Nanyang First People's Hospital, Henan Province, 473002, P.R. China.
Jiao P; School of Life Science and Technology, Nanyang Normal University, Nanyang, Henan Province 473061, P.R. China.
Zhang X; School of Life Science and Technology, Nanyang Normal University, Nanyang, Henan Province 473061, P.R. China.
Yang G; Biochemical Engineering Research Centre, Anhui University of Technology, Ma'anshan, Anhui Province 243032, P.R. China.; School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma'anshan, Anhui Province 243032, P.R. China.
Xu X; Biochemical Engineering Research Centre, Anhui University of Technology, Ma'anshan, Anhui Province 243032, P.R. China.; School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma'anshan, Anhui Province 243032, P.R. China.; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P.R. China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Feb 03; Vol. 13 (4), pp. 4853-4860. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*administration & dosage
Cell-Penetrating Peptides/*chemistry
Drug Carriers/*chemistry
Paclitaxel/*administration & dosage
Antineoplastic Agents, Phytogenic/pharmacokinetics ; Antineoplastic Agents, Phytogenic/pharmacology ; Cell Survival/drug effects ; HeLa Cells ; Humans ; Hydrophobic and Hydrophilic Interactions ; Molecular Dynamics Simulation ; Paclitaxel/pharmacokinetics ; Paclitaxel/pharmacology
Czasopismo naukowe
Tytuł :
In vitro screening of plant extracts traditionally used as cancer remedies in Ghana - 15-Hydroxyangustilobine A as the active principle in Alstonia boonei leaves.
Autorzy :
Spiegler V; University of Münster, Institute for Pharmaceutical Biology and Phytochemistry, Corrensstrasse 48, D-48149, Münster, Germany. Electronic address: .
Greiffer L; University of Münster, Institute for Pharmaceutical Biology and Phytochemistry, Corrensstrasse 48, D-48149, Münster, Germany.
Jacobtorweihen J; University of Münster, Institute for Pharmaceutical Biology and Phytochemistry, Corrensstrasse 48, D-48149, Münster, Germany.
Asase A; Department of Plant and Environmental Biology, University of Ghana, Legon, Accra, Ghana.
Lanvers-Kaminsky C; University Children's Hospital Münster - Pediatric Hematology and Oncology, Albert Schweitzer-Campus 1A1, University Hospital Münster, Germany.
Hempel G; University of Münster, Institute for Pharmaceutical and Medicinal Chemistry - Clinical Pharmacy, Corrensstrasse 48, D-48149, Münster, Germany.
Agyare C; Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Hensel A; University of Münster, Institute for Pharmaceutical Biology and Phytochemistry, Corrensstrasse 48, D-48149, Münster, Germany.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jan 30; Vol. 265, pp. 113359. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Neoplasms/*drug therapy
Plant Extracts/*pharmacology
Plants, Medicinal/*chemistry
Alstonia/chemistry ; Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Line, Tumor ; Chromatography, High Pressure Liquid ; Dose-Response Relationship, Drug ; Ghana ; Humans ; Inhibitory Concentration 50 ; Medicine, African Traditional ; Neoplasms/pathology ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł :
Mechanisms of Fritillariae Thunbergii Flos in lung cancer treatment from a systems pharmacology perspective.
Autorzy :
Cui M; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, No.888 Yinxian Road, 315100, Ningbo, Zhejiang, People's Republic of China. Electronic address: .
Chen S; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, No.888 Yinxian Road, 315100, Ningbo, Zhejiang, People's Republic of China.
Wang H; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, No.888 Yinxian Road, 315100, Ningbo, Zhejiang, People's Republic of China.
Pan P; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, No.888 Yinxian Road, 315100, Ningbo, Zhejiang, People's Republic of China.
Luo Y; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, No.888 Yinxian Road, 315100, Ningbo, Zhejiang, People's Republic of China.
Sha X; Department of Traditional Chinese Medicine, Zhejiang Pharmaceutical College, No.888 Yinxian Road, 315100, Ningbo, Zhejiang, People's Republic of China.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Jan 10; Vol. 264, pp. 113245. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
Fritillaria*/genetics
Antineoplastic Agents, Phytogenic/*therapeutic use
Drugs, Chinese Herbal/*therapeutic use
Lung Neoplasms/*drug therapy
Protein Interaction Maps/*drug effects
Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Carcinoma, Lewis Lung/drug therapy ; Carcinoma, Lewis Lung/genetics ; Carcinoma, Lewis Lung/pathology ; Drug Screening Assays, Antitumor/methods ; Drugs, Chinese Herbal/isolation & purification ; Drugs, Chinese Herbal/pharmacology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred C57BL ; Protein Interaction Maps/physiology ; Random Allocation ; Treatment Outcome ; Tumor Burden/drug effects ; Tumor Burden/physiology
Czasopismo naukowe
Tytuł :
Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes.
Autorzy :
Jiménez-López J; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain; Instituto Biosanitario de Granada (ibs. GRANADA), 18014, Granada, Spain; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18012, Granada, Spain.
Bravo-Caparrós I; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18012, Granada, Spain.
Cabeza L; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain; Instituto Biosanitario de Granada (ibs. GRANADA), 18014, Granada, Spain; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18012, Granada, Spain.
Nieto FR; Department of Pharmacology, Institute of Neuroscience, Biomedical Research Center (CIBM), University of Granada, 18100, Granada, Spain.
Ortiz R; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain; Instituto Biosanitario de Granada (ibs. GRANADA), 18014, Granada, Spain; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18012, Granada, Spain.
Perazzoli G; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain; Instituto Biosanitario de Granada (ibs. GRANADA), 18014, Granada, Spain.
Fernández-Segura E; Department of Histology, Institute of Neuroscience, Biomedical Research Center (CIBM), University of Granada, 18100, Granada, Spain.
Cañizares FJ; Department of Histology, Institute of Neuroscience, Biomedical Research Center (CIBM), University of Granada, 18100, Granada, Spain.
Baeyens JM; Department of Pharmacology, Institute of Neuroscience, Biomedical Research Center (CIBM), University of Granada, 18100, Granada, Spain.
Melguizo C; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain; Instituto Biosanitario de Granada (ibs. GRANADA), 18014, Granada, Spain; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18012, Granada, Spain. Electronic address: .
Prados J; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain; Instituto Biosanitario de Granada (ibs. GRANADA), 18014, Granada, Spain; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18012, Granada, Spain.
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 111059. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*administration & dosage
Lipids/*chemistry
Lung Neoplasms/*drug therapy
Paclitaxel/*administration & dosage
Polyethylene Glycols/*chemistry
A549 Cells ; Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/pharmacokinetics ; Antineoplastic Agents, Phytogenic/toxicity ; Cations ; Cell Proliferation/drug effects ; Drug Compounding ; Female ; Ganglia, Spinal/drug effects ; Humans ; Liposomes ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mice, Inbred C57BL ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Paclitaxel/chemistry ; Paclitaxel/pharmacokinetics ; Paclitaxel/toxicity ; Particle Size ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/prevention & control ; Tumor Burden
Czasopismo naukowe
Tytuł :
Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model.
Autorzy :
Mendes Miranda SE; Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Alcântara Lemos J; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Fernandes RS; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Silva JO; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Ottoni FM; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Townsend DM; Department of Drug Discovery and Pharmaceutical Sciences, Medical University of South Carolina, USA.
Rubello D; Department of Nuclear Medicine, Santa Maria della Misericordia Hospital, Rovigo, Italy.
Alves RJ; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
Cassali GD; Department of General Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Ferreira LAM; Department of Pharmaceutical Products, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil.
de Barros ALB; Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, Minas Gerais, Brazil. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 110936. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Nanoparticles*
Antineoplastic Agents, Phytogenic/*pharmacology
Breast Neoplasms/*drug therapy
Naphthoquinones/*pharmacology
Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/pharmacokinetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Drug Compounding ; Drug Liberation ; Drug Stability ; Emulsions ; Female ; Humans ; Mice, Inbred BALB C ; Naphthoquinones/chemistry ; Naphthoquinones/pharmacokinetics ; Tumor Burden
Czasopismo naukowe
Tytuł :
Novel Chinese Angelica Polysaccharide Biomimetic Nanomedicine to Curcumin Delivery for Hepatocellular Carcinoma Treatment and Immunomodulatory Effect.
Autorzy :
Guo C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, P.R. China.
Hou X; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, P.R. China; Weifang Institute of Chinese Medical Sciences and Industrial Technology, Weifang 261100, P.R.China.
Liu Y; State Key Laboratory of Bio-Fibers and Eco-Textiles,Qingdao University, Qingdao, Shandong, 266071, P.R. China.
Zhang Y; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230013, China; Weifang Institute of Chinese Medical Sciences and Industrial Technology, Weifang 261100, P.R.China.
Xu H; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, P.R. China; Weifang Institute of Chinese Medical Sciences and Industrial Technology, Weifang 261100, P.R.China.
Zhao F; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, P.R. China; Weifang Institute of Chinese Medical Sciences and Industrial Technology, Weifang 261100, P.R.China.
Chen D; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, P.R. China; State Key Laboratory of Bio-Fibers and Eco-Textiles,Qingdao University, Qingdao, Shandong, 266071, P.R. China; Weifang Institute of Chinese Medical Sciences and Industrial Technology, Weifang 261100, P.R.China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Jan; Vol. 80, pp. 153356. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*administration & dosage
Carcinoma, Hepatocellular/*drug therapy
Curcumin/*administration & dosage
Liver Neoplasms/*drug therapy
Polysaccharides/*chemistry
Angelica/chemistry ; Animals ; Antineoplastic Agents, Phytogenic/immunology ; Antineoplastic Agents, Phytogenic/pharmacology ; Biomimetics ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/pathology ; Curcumin/pharmacology ; Drug Carriers/administration & dosage ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Female ; Hep G2 Cells ; Humans ; Immunologic Factors/administration & dosage ; Immunologic Factors/pharmacology ; Liver Neoplasms/immunology ; Liver Neoplasms/pathology ; Mice, Nude ; Micelles ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Tissue Distribution ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Interactions of the major effective components in Shengmai formula with breast cancer resistance protein at the cellular and vesicular levels.
Autorzy :
Wu L; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Liu J; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Hou J; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Zhan T; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Yuan L; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Liu F; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Xiong Y; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China.
Hu J; Drug Clinical Research Center, the First Affiliated Hospital of Nanchang University, Nanchang 330006, PR China. Electronic address: .
Xia C; Clinical Pharmacology Institute, Nanchang University, Nanchang 330006, PR China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 110939. Date of Electronic Publication: 2020 Nov 21.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
ATP Binding Cassette Transporter, Subfamily G, Member 2/*antagonists & inhibitors
Antineoplastic Agents, Phytogenic/*pharmacology
Drugs, Chinese Herbal/*pharmacology
Neoplasm Proteins/*antagonists & inhibitors
Transport Vesicles/*drug effects
ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Animals ; Antineoplastic Agents, Phytogenic/analysis ; Antineoplastic Agents, Phytogenic/metabolism ; Biological Transport ; Drug Combinations ; Drugs, Chinese Herbal/analysis ; Drugs, Chinese Herbal/metabolism ; LLC-PK1 Cells ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Swine ; Transport Vesicles/genetics ; Transport Vesicles/metabolism
Czasopismo naukowe
Tytuł :
Eupholides A-H, abietane diterpenoids from the roots of Euphorbia fischeriana, and their bioactivities.
Autorzy :
Li DW; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People's Republic of China.
Deng XP; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China.
He X; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China.
Han XY; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China.
Ma YF; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China.
Huang HL; Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, People's Republic of China.
Yu ZL; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China.
Feng L; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China.
Wang C; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China. Electronic address: .
Ma XC; Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention, College of Pharmacy, Academy of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116044, People's Republic of China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, People's Republic of China. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2021 Mar; Vol. 183, pp. 112593. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic*
Euphorbia*
Abietanes/pharmacology ; China ; Diterpenes/pharmacology ; Molecular Structure ; Plant Roots
Czasopismo naukowe
Tytuł :
Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells.
Autorzy :
Mbaveng AT; Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: .
Chi GF; Department of Chemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon. Electronic address: .
Bonsou IN; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: .
Ombito JO; Department of Chemistry, University of Botswana, Private Bag 0022, Gaborone, Botswana. Electronic address: .
Yeboah SO; Department of Chemistry, University of Botswana, Private Bag 0022, Gaborone, Botswana. Electronic address: .
Kuete V; Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: .
Efferth T; Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113632. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Drug Resistance, Multiple*
Drug Resistance, Neoplasm*
Fruit*/chemistry
Tetrapleura*/chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Neoplasms/*drug therapy
Phytochemicals/*pharmacology
Plant Extracts/*pharmacology
Antineoplastic Agents, Phytogenic/isolation & purification ; Caspases/metabolism ; Dose-Response Relationship, Drug ; HCT116 Cells ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Matrix Metalloproteinases/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Neoplasms/metabolism ; Neoplasms/pathology ; Oxidative Stress/drug effects ; Phytochemicals/isolation & purification ; Plant Extracts/isolation & purification ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
A lipid-soluble extract of Pinellia pedatisecta Schott orchestrates intratumoral dendritic cell-driven immune activation through SOCS1 signaling in cervical cancer.
Autorzy :
Wang Y; Department of Integration of Western and Traditional Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai, 200011, China.
Lu C; Department of Integration of Western and Traditional Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai, 200011, China.
Huang H; Department of Integration of Western and Traditional Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai, 200011, China.
Yao S; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Xu C; Department of Integration of Western and Traditional Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai, 200011, China.
Ye Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Gui S; Department of Integration of Western and Traditional Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai, 200011, China.
Li G; Department of Integration of Western and Traditional Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200090, China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Fudan University, Shanghai, 200011, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 112837. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Pinellia*/chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Dendritic Cells/*drug effects
Immunologic Factors/*pharmacology
Plant Extracts/*pharmacology
Suppressor of Cytokine Signaling 1 Protein/*metabolism
Uterine Cervical Neoplasms/*drug therapy
Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Line, Tumor ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunologic Factors/isolation & purification ; Janus Kinase 2/metabolism ; Lipids/chemistry ; Mice ; Mice, Inbred C57BL ; Plant Extracts/isolation & purification ; STAT Transcription Factors/metabolism ; Signal Transduction ; Solvents/chemistry ; Suppressor of Cytokine Signaling 1 Protein/genetics ; Tumor Cells, Cultured ; Uterine Cervical Neoplasms/immunology ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Antigenotoxic, antiproliferative and antimetastatic properties of a combination of native medicinal plants from Argentina.
Autorzy :
Carabajal MPA; Instituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, San Lorenzo 1469, 4000, San Miguel de Tucumán, Tucumán, Argentina. Electronic address: .
Piloto-Ferrer J; Departamento de Toxicología Genética y Antitumorales, Centro de Investigación y Desarrollo de Medicamentos (CIDEM), Avenida 26, No. 1605 e/Puentes Grandes y Boyeros, La Habana, Cuba. Electronic address: .
Nicollela HD; Universidade de Franca, Avenida Dr. Armando Salles de Oliveira, 201, 14404-600, Franca, São Paulo, Brazil. Electronic address: .
Squarisi IS; Universidade de Franca, Avenida Dr. Armando Salles de Oliveira, 201, 14404-600, Franca, São Paulo, Brazil. Electronic address: .
Prado Guissone AP; Universidade de Franca, Avenida Dr. Armando Salles de Oliveira, 201, 14404-600, Franca, São Paulo, Brazil. Electronic address: .
Esperandim TR; Universidade de Franca, Avenida Dr. Armando Salles de Oliveira, 201, 14404-600, Franca, São Paulo, Brazil. Electronic address: .
Tavares DC; Universidade de Franca, Avenida Dr. Armando Salles de Oliveira, 201, 14404-600, Franca, São Paulo, Brazil. Electronic address: .
Isla MI; Instituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, San Lorenzo 1469, 4000, San Miguel de Tucumán, Tucumán, Argentina. Electronic address: .
Zampini IC; Instituto de Bioprospección y Fisiología Vegetal (INBIOFIV-CONICET-UNT), Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, San Lorenzo 1469, 4000, San Miguel de Tucumán, Tucumán, Argentina. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113479. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Fabaceae*/chemistry
Larrea*/chemistry
Antimutagenic Agents/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Cell Proliferation/*drug effects
DNA Damage/*drug effects
Neoplasms/*drug therapy
Plant Extracts/*pharmacology
Animals ; Antimutagenic Agents/isolation & purification ; Antineoplastic Agents, Phytogenic/isolation & purification ; Argentina ; CHO Cells ; Cricetulus ; HeLa Cells ; Humans ; MCF-7 Cells ; Male ; Medicine, Traditional ; Mice, Inbred BALB C ; Neoplasm Metastasis ; Neoplasms/pathology ; Phytotherapy ; Plant Extracts/isolation & purification ; Plants, Medicinal
Czasopismo naukowe
Tytuł :
The water expelling effect evaluation of 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol and ingenol on H22 mouse hepatoma ascites model and their content differences analysis in Euphorbia kansui before and after stir-fried with vinegar by UPLC.
Autorzy :
Zhang Q; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, Shaanxi University of Chinese Medicine, Xi'an, 712046, Shaanxi Province, China. Electronic address: .
Ju YH; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Zhang Y; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Wang K; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Zhang M; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Chen PD; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Yao WF; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Tang YP; Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, Shaanxi University of Chinese Medicine, Xi'an, 712046, Shaanxi Province, China. Electronic address: .
Wu JH; Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, Shaanxi University of Chinese Medicine, Xi'an, 712046, Shaanxi Province, China. Electronic address: .
Zhang L; Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113507. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, High Pressure Liquid*
Cooking*
Euphorbia*/chemistry
Acetic Acid/*chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Ascites/*prevention & control
Carcinoma, Hepatocellular/*drug therapy
Diterpenes/*pharmacology
Liver Neoplasms/*drug therapy
Plant Extracts/*pharmacology
Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Aquaporin 2/metabolism ; Aquaporins/metabolism ; Ascites/metabolism ; Ascites/pathology ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cytokines/metabolism ; Diterpenes/isolation & purification ; Female ; Hot Temperature ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Male ; Mice ; Mice, Inbred ICR ; Plant Extracts/isolation & purification ; Receptors, Vasopressin/metabolism ; Renin-Angiotensin System/drug effects ; Signal Transduction
Czasopismo naukowe
Tytuł :
Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells.
Autorzy :
Beeby E; Department of Biomedical Sciences, Faculty of Health Sciences, University of Hull, HU6 7RX, UK.
Magalhães M; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Clinic Academic Center of Coimbra (CACC), Faculty of Medicine, 3000-548 Coimbra, Portugal; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), 3000-548 Coimbra, Portugal.
Lemos MFL; MARE - Marine and Environmental Sciences Centre, ESTM, Polytechnic of Leiria, 2520-641, Peniche, Portugal.
Pires IM; Department of Biomedical Sciences, Faculty of Health Sciences, University of Hull, HU6 7RX, UK. Electronic address: .
Cabral C; University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Clinic Academic Center of Coimbra (CACC), Faculty of Medicine, 3000-548 Coimbra, Portugal; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), 3000-548 Coimbra, Portugal; Centre for Functional Ecology, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113515. Date of Electronic Publication: 2020 Oct 24.
Typ publikacji :
Journal Article
MeSH Terms :
Apiaceae*/chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Breast Neoplasms/*drug therapy
Colorectal Neoplasms/*drug therapy
Oils, Volatile/*pharmacology
Plant Oils/*pharmacology
Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Cycle Checkpoints/drug effects ; Cell Proliferation/drug effects ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; HEK293 Cells ; Humans ; MCF-7 Cells ; Oils, Volatile/isolation & purification ; Plant Oils/isolation & purification ; Signal Transduction ; Spheroids, Cellular
Czasopismo naukowe
Tytuł :
Antiproliferative and antitumour activity of saponins from Astragalus glycyphyllos on myeloid Graffi tumour.
Autorzy :
Georgieva A; Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 25, 1113, Sofia, Bulgaria. Electronic address: .
Popov G; Department of Internal Non-communicable Diseases, Pathology and Pharmacology, Faculty of Veterinary Medicine, University of Forestry, 10 St. Kliment Ohridski Blvd., 1797, Sofia, Bulgaria. Electronic address: .
Shkondrov A; Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav St., 1000, Sofia, Bulgaria. Electronic address: .
Toshkova R; Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 25, 1113, Sofia, Bulgaria. Electronic address: .
Krasteva I; Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav St., 1000, Sofia, Bulgaria. Electronic address: .
Kondeva-Burdina M; Laboratory of Drug Metabolism and Drug Toxicity, Department of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav St., 1000, Sofia, Bulgaria. Electronic address: .
Manov V; Department of Internal Non-communicable Diseases, Pathology and Pharmacology, Faculty of Veterinary Medicine, University of Forestry, 10 St. Kliment Ohridski Blvd., 1797, Sofia, Bulgaria. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113519. Date of Electronic Publication: 2020 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Astragalus Plant*/chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Cell Proliferation/*drug effects
Leukemia, Experimental/*drug therapy
Plant Extracts/*pharmacology
Saponins/*pharmacology
Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Cricetinae ; Female ; Leukemia Virus, Murine/pathogenicity ; Leukemia, Experimental/pathology ; Leukemia, Experimental/virology ; Male ; Mesocricetus ; Plant Extracts/isolation & purification ; Primary Cell Culture ; Retroviridae Infections/virology ; Saponins/isolation & purification ; Tumor Burden/drug effects ; Tumor Cells, Cultured ; Tumor Virus Infections/virology
Czasopismo naukowe
Tytuł :
Strobilanthes crispus bioactive subfraction inhibits tumor progression and improves hematological and morphological parameters in mouse mammary carcinoma model.
Autorzy :
Baraya YS; Department of Veterinary Pathology, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Nigeria. Electronic address: .
Yankuzo HM; Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria. Electronic address: .
Wong KK; Department of Immunology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Kelantan, Malaysia. Electronic address: .
Yaacob NS; Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Kelantan, Malaysia. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113522. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Breast Neoplasms/*drug therapy
Kidney Neoplasms/*prevention & control
Liver Neoplasms/*prevention & control
Lung Neoplasms/*prevention & control
Plant Extracts/*pharmacology
Splenic Neoplasms/*prevention & control
Acanthaceae/chemistry ; Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Breast Neoplasms/blood ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Female ; Kidney Neoplasms/blood ; Kidney Neoplasms/secondary ; Liver Neoplasms/blood ; Liver Neoplasms/secondary ; Lung Neoplasms/blood ; Lung Neoplasms/secondary ; Lutein/pharmacology ; Mice, Inbred BALB C ; Plant Extracts/isolation & purification ; Sitosterols/pharmacology ; Splenic Neoplasms/blood ; Splenic Neoplasms/secondary ; Tumor Burden/drug effects
Czasopismo naukowe

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