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Wyszukujesz frazę ""platelet activation"" wg kryterium: Temat


Tytuł :
COVID-19 patients exhibit reduced procoagulant platelet responses.
Autorzy :
Denorme F; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.
Manne BK; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.
Portier I; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.
Petrey AC; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT, USA.
Middleton EA; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
Kile BT; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia.
Rondina MT; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.; George E. Wahlen VAMC Department of Internal Medicine and GRECC, Salt Lake City, UT, USA.
Campbell RA; University of Utah Molecular Medicine Program, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2020 Nov; Vol. 18 (11), pp. 3067-3073. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Coagulation*
Platelet Activation*
Blood Platelets/*metabolism
COVID-19/*complications
Thrombosis/*etiology
Adult ; Aged ; Animals ; COVID-19/blood ; COVID-19/diagnosis ; Case-Control Studies ; Cyclophilin D/blood ; Cyclophilin D/genetics ; Disease Models, Animal ; Female ; Humans ; Male ; Mice, Knockout ; Middle Aged ; Thrombosis/blood ; Thrombosis/diagnosis
Czasopismo naukowe
Tytuł :
Platelet activation and placenta-mediated adverse pregnancy outcomes: an ancillary study to the Effects of Aspirin in Gestation and Reproduction trial.
Autorzy :
Theilen LH; Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT; Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT. Electronic address: .
Campbell HD; Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT; Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT.
Mumford SL; Division of Intramural Population Health Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
Purdue-Smithe AC; Division of Intramural Population Health Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
Sjaarda LA; Division of Intramural Population Health Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
Perkins NJ; Division of Intramural Population Health Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
Radoc JG; Division of Intramural Population Health Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
Silver RM; Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT; Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT.
Schisterman EF; Division of Intramural Population Health Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
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Źródło :
American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2020 Nov; Vol. 223 (5), pp. 741.e1-741.e12. Date of Electronic Publication: 2020 May 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Platelet Activation*
Abruptio Placentae/*epidemiology
Aspirin/*therapeutic use
Fetal Growth Retardation/*epidemiology
Hypertension, Pregnancy-Induced/*epidemiology
Platelet Aggregation Inhibitors/*therapeutic use
Platelet Factor 4/*blood
Abruptio Placentae/blood ; Adult ; Female ; Fetal Growth Retardation/blood ; Humans ; Hypertension, Pregnancy-Induced/blood ; Infant, Small for Gestational Age ; Preconception Care ; Pregnancy ; Pregnancy Trimester, First/blood ; Pregnancy Trimester, Second/blood ; Young Adult
Czasopismo naukowe
Tytuł :
Mean Platelet Volume/Platelet Count Ratio is Associated with Poor Clinical Outcome After Aneurysmal Subarachnoid Hemorrhage.
Autorzy :
Wang Z; Department of Neurosurgery, The First People's Hospital of Jingmen, Jingmen, Hubei, PR China.
Pei W; Department of Neurology, The First People's Hospital of Jingmen, Jingmen, Hubei, PR China.
Chen L; Department of Neurosurgery, The First People's Hospital of Jingmen, Jingmen, Hubei, PR China.
Ning Y; Department of Neurosurgery, The First People's Hospital of Jingmen, Jingmen, Hubei, PR China.
Luo Y; Department of Neurosurgery, The First People's Hospital of Jingmen, Jingmen, Hubei, PR China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Nov; Vol. 29 (11), pp. 105208. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets*
Mean Platelet Volume*
Platelet Activation*
Platelet Count*
Subarachnoid Hemorrhage/*diagnosis
Adult ; Aged ; Aged, 80 and over ; Disability Evaluation ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Recovery of Function ; Reproducibility of Results ; Retrospective Studies ; Subarachnoid Hemorrhage/blood ; Subarachnoid Hemorrhage/physiopathology ; Subarachnoid Hemorrhage/therapy ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The JUUL E-Cigarette Elevates the Risk of Thrombosis and Potentiates Platelet Activation.
Autorzy :
Ramirez JEM; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.
Karim ZA; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.
Alarabi AB; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, 12333Texas A&M University, Kingsville, TX, USA.
Hernandez KR; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.
Taleb ZB; Department of Kinesiology, 12329University of Texas at Arlington, Arlington, TX, USA.
Rivera JO; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.
Khasawneh FT; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, 12333Texas A&M University, Kingsville, TX, USA.
Alshbool FZ; Department of Pharmaceutical Sciences, School of Pharmacy, 12337The University of Texas El Paso, El Paso, TX, USA.; Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, 12333Texas A&M University, Kingsville, TX, USA.
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Źródło :
Journal of cardiovascular pharmacology and therapeutics [J Cardiovasc Pharmacol Ther] 2020 Nov; Vol. 25 (6), pp. 578-586. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Electronic Nicotine Delivery Systems*
Platelet Activation*
Blood Platelets/*metabolism
Carotid Artery Thrombosis/*etiology
E-Cigarette Vapor/*adverse effects
Vaping/*adverse effects
Animals ; Carotid Artery Thrombosis/blood ; Disease Models, Animal ; Male ; Mice, Inbred C57BL ; Phosphatidylserines/blood ; Platelet Aggregation ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Signal Transduction ; Vaping/blood
Czasopismo naukowe
Tytuł :
Platelet Dysfunction and Thrombosis in JAK2 -Mutated Primary Myelofibrotic Mice.
Autorzy :
Matsuura S; Department of Medicine and Whitaker Cardiovascular Institute (S.M., C.R.T., A.P., O.L., K.R.), Boston University School of Medicine, MA.
Thompson CR; Department of Medicine and Whitaker Cardiovascular Institute (S.M., C.R.T., A.P., O.L., K.R.), Boston University School of Medicine, MA.
Belghasem ME; Department of Pathology (M.E.B.), Boston University School of Medicine, MA.
Bekendam RH; Department of Medicine (R.H.B.), Boston University School of Medicine, MA.
Piasecki A; Department of Medicine and Whitaker Cardiovascular Institute (S.M., C.R.T., A.P., O.L., K.R.), Boston University School of Medicine, MA.
Leiva O; Department of Medicine and Whitaker Cardiovascular Institute (S.M., C.R.T., A.P., O.L., K.R.), Boston University School of Medicine, MA.
Ray A; Department of Medicine, Brigham and Women's Hospital, Boston MA (A.R., J.I.).
Italiano J; Department of Medicine, Brigham and Women's Hospital, Boston MA (A.R., J.I.).
Yang M; Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.Y., G.M.-S., R.F.).
Merill-Skoloff G; Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.Y., G.M.-S., R.F.).
Chitalia VC; Renal Section, Department of Medicine (V.C.C.), Boston University School of Medicine, MA.
Flaumenhaft R; Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.Y., G.M.-S., R.F.).
Ravid K; Department of Medicine and Whitaker Cardiovascular Institute (S.M., C.R.T., A.P., O.L., K.R.), Boston University School of Medicine, MA.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Oct; Vol. 40 (10), pp. e262-e272. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Coagulation*
Platelet Activation*
Blood Platelets/*enzymology
Carotid Artery Injuries/*enzymology
Janus Kinase 2/*blood
Megakaryocytes/*enzymology
Primary Myelofibrosis/*enzymology
Thrombosis/*enzymology
Animals ; Carotid Artery Injuries/blood ; Carotid Artery Injuries/genetics ; Disease Models, Animal ; Janus Kinase 2/genetics ; Mice, Transgenic ; Mutation ; Platelet Aggregation ; Primary Myelofibrosis/blood ; Primary Myelofibrosis/genetics ; Thrombopoiesis ; Thrombosis/blood ; Thrombosis/genetics
Czasopismo naukowe
Tytuł :
In vitro comparison of three percutaneous atrial septal defect closure devices for endothelialisation and haemocompatibility.
Autorzy :
Levy Y; Department of Paediatric and Adult Congenital Cardiology, Bordeaux University Hospital (CHU), 33600 Pessac, France. Electronic address: .
Jalal Z; Department of Paediatric and Adult Congenital Cardiology, Bordeaux University Hospital (CHU), 33600 Pessac, France; IHU Liryc, Electrophysiology and Heart Modelling Institute, Fondation Bordeaux Université, 33600 Pessac, France; Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, INSERM, 33000 Bordeaux, France.
Aussel A; Université de Bordeaux, 33000 Bordeaux, France; Bioingénierie Tissulaire, U1026, INSERM, 33000 Bordeaux, France; CHU de Bordeaux, 33000 Bordeaux, France.
Thebaud NB; Université de Bordeaux, 33000 Bordeaux, France; Bioingénierie Tissulaire, U1026, INSERM, 33000 Bordeaux, France; CHU de Bordeaux, 33000 Bordeaux, France.
Renard M; CIC 1401, CHU de Bordeaux, 33000 Bordeaux, France.
Bareille R; Université de Bordeaux, 33000 Bordeaux, France; Bioingénierie Tissulaire, U1026, INSERM, 33000 Bordeaux, France.
Ripoche J; Université de Bordeaux, 33000 Bordeaux, France; Bioingénierie Tissulaire, U1026, INSERM, 33000 Bordeaux, France.
Durand M; CIC 1401, CHU de Bordeaux, 33000 Bordeaux, France.
Thambo JB; Department of Paediatric and Adult Congenital Cardiology, Bordeaux University Hospital (CHU), 33600 Pessac, France; IHU Liryc, Electrophysiology and Heart Modelling Institute, Fondation Bordeaux Université, 33600 Pessac, France; Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, INSERM, 33000 Bordeaux, France.
Bordenave L; Université de Bordeaux, 33000 Bordeaux, France; Bioingénierie Tissulaire, U1026, INSERM, 33000 Bordeaux, France; CHU de Bordeaux, 33000 Bordeaux, France; CIC 1401, CHU de Bordeaux, 33000 Bordeaux, France.
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Źródło :
Archives of cardiovascular diseases [Arch Cardiovasc Dis] 2020 Aug - Sep; Vol. 113 (8-9), pp. 503-512. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Blood Coagulation*
Complement Activation*
Platelet Activation*
Re-Epithelialization*
Septal Occluder Device*
Cardiac Catheterization/*instrumentation
Endothelial Progenitor Cells/*pathology
Cardiac Catheterization/adverse effects ; Cell Adhesion ; Cell Proliferation ; Cells, Cultured ; Endothelial Progenitor Cells/metabolism ; Humans ; Materials Testing ; Prosthesis Design ; Risk Assessment ; Time Factors
Czasopismo naukowe
Tytuł :
Abnormal platelet phenotypes in patients with myelodysplastic syndromes.
Autorzy :
Liu J; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Niu H; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Yue L; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Lv Q; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Yang L; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Liu C; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Jiang H; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Xing L; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Shao Z; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
Wang H; Department of Hematology, General Hospital, Tianjin Medical University, Tianjin, China.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2020 Aug; Vol. 42 (4), pp. 371-379. Date of Electronic Publication: 2020 Mar 23.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Gene Expression Regulation*
Platelet Activation*
Blood Platelets/*metabolism
Myelodysplastic Syndromes/*blood
Platelet Membrane Glycoproteins/*biosynthesis
Adult ; Aged ; Aged, 80 and over ; Blood Platelets/immunology ; Blood Platelets/pathology ; Female ; Humans ; Male ; Middle Aged ; Myelodysplastic Syndromes/immunology ; Myelodysplastic Syndromes/pathology ; Myelodysplastic Syndromes/therapy ; Platelet Membrane Glycoproteins/immunology
Czasopismo naukowe
Tytuł :
Periodontal treatment does not result in detectable platelet activation in vivo.
Autorzy :
Laky M; Division of Conservative Dentistry and Periodontology, School of Dentistry, Medical University of Vienna, Vienna, Austria.
Anscheringer I; Department for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, Vienna, 1090, Austria.
Wolschner L; Division of Conservative Dentistry and Periodontology, School of Dentistry, Medical University of Vienna, Vienna, Austria.
Heber S; Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Haririan H; Division of Conservative Dentistry and Periodontology, School of Dentistry, Medical University of Vienna, Vienna, Austria.
Rausch-Fan X; Division of Conservative Dentistry and Periodontology, School of Dentistry, Medical University of Vienna, Vienna, Austria.
Volf I; Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
Moritz A; Division of Conservative Dentistry and Periodontology, School of Dentistry, Medical University of Vienna, Vienna, Austria.
Assinger A; Department for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, Vienna, 1090, Austria. .
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Źródło :
Clinical oral investigations [Clin Oral Investig] 2020 May; Vol. 24 (5), pp. 1853-1859. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Periodontal Debridement*
Periodontics*
Platelet Activation*
Periodontitis/*prevention & control
Blood Platelets ; Dental Care ; Humans ; Prospective Studies
Czasopismo naukowe
Tytuł :
Recent Insights Into the Regulation of Coagulation and Thrombosis.
Autorzy :
Li X; From the Saha Cardiovascular Research Center (X.L., J.P.W.), University of Kentucky, Lexington.
Sim MMS; Department of Molecular and Cellular Biochemistry (M.M.S.S., J.P.W.), University of Kentucky, Lexington.
Wood JP; From the Saha Cardiovascular Research Center (X.L., J.P.W.), University of Kentucky, Lexington.; Department of Molecular and Cellular Biochemistry (M.M.S.S., J.P.W.), University of Kentucky, Lexington.; Division of Cardiovascular Medicine (J.P.W.), University of Kentucky, Lexington.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 May; Vol. 40 (5), pp. e119-e125. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Blood Coagulation*/drug effects
Platelet Activation*/drug effects
Blood Platelets/*metabolism
Thrombin/*metabolism
Thromboplastin/*metabolism
Thrombosis/*blood
Animals ; Anticoagulants/therapeutic use ; Blood Platelets/drug effects ; Fibrinolytic Agents/therapeutic use ; Humans ; Platelet Aggregation Inhibitors/therapeutic use ; Signal Transduction ; Thrombosis/drug therapy
Czasopismo naukowe
Tytuł :
Effects of bacterial lipopolysaccharides on platelet function: inhibition of weak platelet activation.
Autorzy :
Martyanov AA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia. .; National Medical Research Center of Pediatric Hematology, Oncology and Immunology Named After Dmitry Rogachev, 1 Samory Mashela St., Moscow, 117198, Russia. .; Institute for Biochemical Physics (IBCP), Russian Academy of Sciences (RAS), Kosyigina 4, Moscow, 119334, Russia. .; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie Gory, Moscow, 119991, Russia. .
Maiorov AS; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia.
Filkova AA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia.; National Medical Research Center of Pediatric Hematology, Oncology and Immunology Named After Dmitry Rogachev, 1 Samory Mashela St., Moscow, 117198, Russia.; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie Gory, Moscow, 119991, Russia.
Ryabykh AA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia.; National Medical Research Center of Pediatric Hematology, Oncology and Immunology Named After Dmitry Rogachev, 1 Samory Mashela St., Moscow, 117198, Russia.
Svidelskaya GS; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie Gory, Moscow, 119991, Russia.
Artemenko EO; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia.; National Medical Research Center of Pediatric Hematology, Oncology and Immunology Named After Dmitry Rogachev, 1 Samory Mashela St., Moscow, 117198, Russia.
Gambaryan SP; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia.
Panteleev MA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia.; National Medical Research Center of Pediatric Hematology, Oncology and Immunology Named After Dmitry Rogachev, 1 Samory Mashela St., Moscow, 117198, Russia.; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie Gory, Moscow, 119991, Russia.
Sveshnikova AN; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow, 109029, Russia.; National Medical Research Center of Pediatric Hematology, Oncology and Immunology Named After Dmitry Rogachev, 1 Samory Mashela St., Moscow, 117198, Russia.; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie Gory, Moscow, 119991, Russia.; Department of Normal Physiology, Sechenov First Moscow State Medical University, 8/2 Trubetskaya St., Moscow, 119991, Russia.
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 23; Vol. 10 (1), pp. 12296. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Platelet Activation*/immunology
Blood Platelets/*immunology
Blood Platelets/*metabolism
Lipopolysaccharides/*immunology
Adenosine Diphosphate/metabolism ; Adolescent ; Adult ; Biomarkers ; Cyclic AMP/metabolism ; Cyclic GMP/metabolism ; Female ; Flow Cytometry ; Humans ; Male ; Neutrophils/immunology ; Neutrophils/metabolism ; Platelet Aggregation/immunology ; Platelet Function Tests ; Signal Transduction ; Young Adult
Czasopismo naukowe
Tytuł :
The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function.
Autorzy :
Bennett JA; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Mastrangelo MA; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Ture SK; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Smith CO; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Loelius SG; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Berg RA; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Shi X; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Burke RM; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Spinelli SL; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Cameron SJ; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Carey TE; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.
Brookes PS; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.; Genomics of Complex Diseases, Research Institute of Hospital de la Santa Creu i Sant Pau (IIB Sant Pau), Barcelona, Spain.
de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Huffman JE; Center for Population Genomics, MAVERIC, VA Boston Healthcare System, Jamaica Plain, MA, USA.
Smith NL; Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA, USA.
Morrell CN; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Lowenstein CJ; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jul 13; Vol. 11 (1), pp. 3479. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Transport Proteins/*metabolism
Mitochondria/*metabolism
Platelet Activation/*physiology
Thrombosis/*metabolism
Adenosine Triphosphate/metabolism ; Animals ; Blotting, Western ; Disease Models, Animal ; Genome-Wide Association Study ; Male ; Mass Spectrometry ; Membrane Transport Proteins/genetics ; Mice ; Mice, Knockout ; Mitochondria/genetics ; Platelet Activation/genetics ; Platelet Aggregation/genetics ; Platelet Aggregation/physiology ; Real-Time Polymerase Chain Reaction ; Thrombosis/genetics
Czasopismo naukowe
Tytuł :
Hypertriglyceridemia is associated with platelet hyperactivation in metabolic syndrome patients.
Autorzy :
Wang T; Department of International Medical Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xu J; Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Fu L; Department of International Medical Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Li L; Department of International Medical Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
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Źródło :
International journal of clinical practice [Int J Clin Pract] 2020 Jul; Vol. 74 (7), pp. e13508. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Platelet Activation*
Cardiovascular Diseases/*blood
Hypertriglyceridemia/*blood
Metabolic Syndrome/*blood
Adult ; Blood Glucose/metabolism ; Body Mass Index ; Case-Control Studies ; Female ; Humans ; Hypertension/blood ; Male ; Middle Aged ; Obesity/complications ; Platelet Aggregation ; Risk Factors ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
Platelets Endocytose Viral Particles and Are Activated via TLR (Toll-Like Receptor) Signaling.
Autorzy :
Banerjee M; Department of Molecular and Cellular Biochemistry (M.B., S.J., G.J.P., M.D.M., S.W.W.), University of Kentucky, Lexington.
Huang Y; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, OH (Y.H.).
Joshi S; Department of Molecular and Cellular Biochemistry (M.B., S.J., G.J.P., M.D.M., S.W.W.), University of Kentucky, Lexington.; Lexington VA Health Care System, KY (S.J., S.W.W.).
Popa GJ; Department of Molecular and Cellular Biochemistry (M.B., S.J., G.J.P., M.D.M., S.W.W.), University of Kentucky, Lexington.
Mendenhall MD; Department of Molecular and Cellular Biochemistry (M.B., S.J., G.J.P., M.D.M., S.W.W.), University of Kentucky, Lexington.
Wang QJ; Department of Ophthalmology and Visual Sciences (Q.J.W.), University of Kentucky, Lexington.
Garvy BA; Department of Microbiology, Immunology and Molecular Genetics (B.A.G.), University of Kentucky, Lexington.
Myint T; Department of Infectious Diseases, Bluegrass Care Clinic, Kentucky Clinic (T.M.), University of Kentucky, Lexington.
Whiteheart SW; Department of Molecular and Cellular Biochemistry (M.B., S.J., G.J.P., M.D.M., S.W.W.), University of Kentucky, Lexington.; Lexington VA Health Care System, KY (S.J., S.W.W.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Jul; Vol. 40 (7), pp. 1635-1650. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Endocytosis*
Platelet Activation*
Virion*
Blood Platelets/*metabolism
HIV Infections/*blood
HIV-1/*pathogenicity
Thrombocytopenia/*blood
Toll-Like Receptors/*blood
ADP-Ribosylation Factors/blood ; ADP-Ribosylation Factors/genetics ; Animals ; Anti-Retroviral Agents/therapeutic use ; Blood Platelets/virology ; Cell Aggregation ; Cells, Cultured ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; HIV Infections/virology ; Humans ; I-kappa B Kinase/blood ; I-kappa B Kinase/genetics ; Leukocytes/metabolism ; Leukocytes/virology ; Mice, Inbred C57BL ; Mice, Knockout ; Myeloid Differentiation Factor 88/blood ; Myeloid Differentiation Factor 88/genetics ; Platelet Factor 4/blood ; Platelet Factor 4/genetics ; Thrombocytopenia/diagnosis ; Thrombocytopenia/virology ; Toll-Like Receptors/deficiency ; Toll-Like Receptors/genetics ; Vesicle-Associated Membrane Protein 3/blood ; Vesicle-Associated Membrane Protein 3/genetics
Czasopismo naukowe
Tytuł :
Human platelets express functional ectonucleotidases that restrict platelet activation signaling.
Autorzy :
Chaurasia SN; Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Kushwaha G; Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Pandey A; Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Dash D; Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jun 18; Vol. 527 (1), pp. 104-109. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Platelet Activation*
5'-Nucleotidase/*metabolism
Apyrase/*metabolism
Blood Platelets/*cytology
5'-Nucleotidase/analysis ; Apyrase/analysis ; Blood Platelets/metabolism ; Calcium/metabolism ; Enzyme Activation ; GPI-Linked Proteins/analysis ; GPI-Linked Proteins/metabolism ; Humans ; Signal Transduction ; Thrombin/metabolism
Czasopismo naukowe
Tytuł :
The endothelial barrier and cancer metastasis: Does the protective facet of platelet function matter?
Autorzy :
Smeda M; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.
Przyborowski K; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.
Stojak M; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.
Chlopicki S; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland; Department of Pharmacology, Jagiellonian University Medical College, Krakow, Poland. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Jun; Vol. 176, pp. 113886. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Platelet Activation*
Blood Platelets/*physiology
Endothelium/*physiology
Neoplasms/*blood
Animals ; Blood Platelets/cytology ; Cell Communication ; Endothelium/cytology ; Humans ; Inflammation/blood ; Neoplasm Metastasis ; Neoplasms/blood supply ; Neoplasms/pathology ; Thrombosis/blood
Czasopismo naukowe
Tytuł :
Establishment of a megakaryoblastic cell line for conventional assessment of platelet calcium signaling.
Autorzy :
Saito H; Department of Biochemistry, Jichi Medical University School of Medicine, Tochigi, 329-0498, Japan.
Hayakawa M; Department of Biochemistry, Jichi Medical University School of Medicine, Tochigi, 329-0498, Japan.
Kamoshita N; Department of Biochemistry, Jichi Medical University School of Medicine, Tochigi, 329-0498, Japan.
Yasumoto A; Department of Clinical Laboratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.
Suzuki-Inoue K; Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, 409-3898, Japan.
Yatomi Y; Department of Clinical Laboratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.
Ohmori T; Department of Biochemistry, Jichi Medical University School of Medicine, Tochigi, 329-0498, Japan. .
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Źródło :
International journal of hematology [Int J Hematol] 2020 Jun; Vol. 111 (6), pp. 786-794. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Signaling*
Megakaryocyte Progenitor Cells*/metabolism
Platelet Activation*
Blood Platelets/*metabolism
Blood Platelets/*physiology
Calcium/*metabolism
Cell Line ; Drug Discovery ; Drug Evaluation, Preclinical ; Green Fluorescent Proteins/metabolism ; Humans ; Phosphatidylinositols/metabolism ; Platelet Aggregation Inhibitors ; Receptors, IgG/metabolism
Czasopismo naukowe
Tytuł :
Procoagulant platelets: Laboratory detection and clinical significance.
Autorzy :
Tohidi-Esfahani I; ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia.; Department of Haematology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Lee CSM; ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia.
Liang HPH; ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia.
Chen VMY; ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia.; Department of Haematology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2020 Jun; Vol. 42 Suppl 1, pp. 59-67.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Algorithms*
Blood Coagulation Disorders*/blood
Blood Coagulation Disorders*/diagnosis
Blood Coagulation Disorders*/therapy
Blood Platelets*/metabolism
Blood Platelets*/pathology
Hemophilia A*/blood
Hemophilia A*/diagnosis
Hemophilia A*/therapy
Platelet Activation*
Thrombosis*/blood
Thrombosis*/diagnosis
Thrombosis*/therapy
Humans
SCR Disease Name :
Scott Syndrome
Czasopismo naukowe
Tytuł :
Modulators of platelet function in aging.
Autorzy :
Iyer KS; Department of Internal Medicine, University of Iowa , Iowa city, USA.
Dayal S; Department of Internal Medicine, University of Iowa , Iowa city, USA.
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Źródło :
Platelets [Platelets] 2020 May 18; Vol. 31 (4), pp. 474-482. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Aging/*drug effects
Blood Platelet Disorders/*drug therapy
Blood Platelets/*drug effects
Platelet Activation/*drug effects
Thrombosis/*complications
Aged ; Aging/immunology ; Aging/metabolism ; Animals ; Blood Platelets/immunology ; Blood Platelets/metabolism ; Comorbidity ; Humans ; Inflammation/immunology ; Oxidative Stress ; Platelet Activation/immunology ; Risk Factors ; Signal Transduction/genetics ; Thrombosis/physiopathology
Czasopismo naukowe
Tytuł :
Platelet Integrin αIIbβ3 Activation is Associated with 25-Hydroxyvitamin D Concentrations in Healthy Adults.
Autorzy :
Aleva FE; Department of Respiratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
Tunjungputri RN; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
van der Vorm LN; Department of Respiratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Synapse Research Institute, Maastricht, The Netherlands.; Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.; Department of Clinical Chemistry and Haematology, GelreZiekenhuizen, Apeldoorn, The Netherlands.
Li Y; Department of Genetics, University Medical Centre Groningen, Nijmegen, The Netherlands.
Heijdra YF; Department of Respiratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
Oosting M; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
Smeekens SP; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
Jaeger M; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
Joosten LAB; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
de Groot PG; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
Netea MG; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.; Department for Genomics and Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany.
van der Ven AJAM; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
de Mast Q; Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; Radboud Centre for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2020 May; Vol. 120 (5), pp. 768-775. Date of Electronic Publication: 2020 May 05.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Platelet Activation*
Blood Platelets/*metabolism
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism
Vitamin D Deficiency/*blood
Adolescent ; Adult ; Biomarkers/blood ; Cell Degranulation ; Female ; Fibrinogen/metabolism ; Healthy Volunteers ; Humans ; Male ; P-Selectin/blood ; Platelet Aggregation ; Polymorphism, Single Nucleotide ; Receptors, Calcitriol/genetics ; Receptors, Calcitriol/metabolism ; Signal Transduction ; Vitamin D/analogs & derivatives ; Vitamin D/blood ; Vitamin D Deficiency/diagnosis ; Vitamin D Deficiency/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1.
Autorzy :
Garshick MS; From the Department of Medicine, Center for the Prevention of Cardiovascular Disease (M.S.G., E.A.F., J.S.B.), New York University School of Medicine.; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.
Tawil M; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.
Barrett TJ; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.
Salud-Gnilo CM; Laboratory for Investigative Dermatology, Rockefeller University, New York (C.M.S.-G, J.G.K.).
Eppler M; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.
Lee A; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.
Scher JU; Division of Rheumatology, Department of Medicine, Psoriatic Arthritis Center (J.U.S.), New York University School of Medicine.
Neimann AL; Ronald O. Perelman Department of Dermatology (A.L.N.), New York University School of Medicine.
Jelic S; Division of Pulmonary, Allergy & Critical Care Medicine, Department of Medicine, Columbia University Medical Center, New York (S.J.).
Mehta NN; Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD (N.N.M.).
Fisher EA; From the Department of Medicine, Center for the Prevention of Cardiovascular Disease (M.S.G., E.A.F., J.S.B.), New York University School of Medicine.; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.
Krueger JG; Laboratory for Investigative Dermatology, Rockefeller University, New York (C.M.S.-G, J.G.K.).
Berger JS; From the Department of Medicine, Center for the Prevention of Cardiovascular Disease (M.S.G., E.A.F., J.S.B.), New York University School of Medicine.; Leon H. Charney Division of Cardiology, Department of Medicine (M.S.G., M.T., T.J.B., M.E., A.L., E.A.F., J.S.B.), New York University School of Medicine.; Division of Hematology, Department of Medicine (J.S.B.), New York University School of Medicine.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 May; Vol. 40 (5), pp. 1340-1351. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Platelet Activation*
Blood Platelets/*enzymology
Cyclooxygenase 1/*blood
Endothelial Cells/*enzymology
Psoriasis/*blood
Adult ; Aspirin/administration & dosage ; Blood Platelets/drug effects ; Cells, Cultured ; Cyclooxygenase 1/genetics ; Cyclooxygenase Inhibitors/administration & dosage ; Endothelial Cells/drug effects ; Female ; Humans ; Male ; Middle Aged ; Platelet Adhesiveness ; Psoriasis/diagnosis ; Psoriasis/drug therapy ; Psoriasis/enzymology ; Severity of Illness Index ; Signal Transduction ; Thromboxane B2/blood ; Treatment Outcome
Czasopismo naukowe

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