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Tytuł:
Physiologically-based pharmacokinetic modeling of the drug-drug interaction between ivacaftor and lefamulin in cystic fibrosis patients.
Autorzy:
Amiel M; Certara UK Ltd., Sheffield, UK.
Ke A; Certara UK Ltd., Sheffield, UK.
Gelone SP; Nabriva Therapeutics US, Inc., Fort Washington, Pennsylvania, USA.
Jones HM; Certara UK Ltd., Sheffield, UK.
Wicha W; Nabriva Therapeutics GmbH, Vienna, Austria.
Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Apr; Vol. 13 (4), pp. 589-598. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/drug therapy
Quinolones*/therapeutic use
Aminophenols*
Diterpenes*
Polycyclic Compounds*
Thioglycolates*
Humans ; Cytochrome P-450 CYP3A Inhibitors/pharmacology ; Cytochrome P-450 CYP3A ; Drug Interactions ; Models, Biological
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dibenzocyclooctadiene Lignans from Schisandra chinensis with Anti-Inflammatory Effects.
Autorzy:
Rybnikář M; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Malaník M; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Šmejkal K; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Švajdlenka E; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Shpet P; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.; Recetox, Faculty of Science, Masaryk University, 62500 Brno, Czech Republic.
Babica P; Recetox, Faculty of Science, Masaryk University, 62500 Brno, Czech Republic.
Dall'Acqua S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padua, Italy.
Smištík O; Department of Molecular Pharmacy, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Jurček O; Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Treml J; Department of Molecular Pharmacy, Faculty of Pharmacy, Masaryk University, 61200 Brno, Czech Republic.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Schisandra*
Lignans*/pharmacology
Polycyclic Compounds*
Cyclooctanes/pharmacology ; Anti-Inflammatory Agents/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular Simulation of SO 2 Separation and Storage Using a Cryptophane-Based Porous Liquid.
Autorzy:
Collado P; Departamento de Física Aplicada, Universidade de Vigo, E36310 Vigo, Spain.
Piñeiro MM; Departamento de Física Aplicada, Universidade de Vigo, E36310 Vigo, Spain.
Pérez-Rodríguez M; Instituto de Química Física Blas Cabrera, Consejo Superior de Investigaciones Científicas (CSIC), E28006 Madrid, Spain.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Dynamics Simulation*
Polycyclic Compounds*
Porosity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design and Synthesis of Pleuromutilin Derivatives as Antibacterial Agents Using Quantitative Structure-Activity Relationship Model.
Autorzy:
Zhang J; Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China.; Shandong Provincial Animal and Poultry Green Health Products Creation Engineering Laboratory, Institute of Poultry Science, Shandong Academy of Agricultural Science, Jinan 250023, China.
Liu Q; Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China.
Zhao H; Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China.
Li G; Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China.
Yi Y; Shandong Provincial Animal and Poultry Green Health Products Creation Engineering Laboratory, Institute of Poultry Science, Shandong Academy of Agricultural Science, Jinan 250023, China.
Shang R; Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Methicillin-Resistant Staphylococcus aureus*
Diterpenes*/chemistry
Polycyclic Compounds*/pharmacology
Pleuromutilins ; Anti-Bacterial Agents/chemistry ; Quantitative Structure-Activity Relationship ; Staphylococcus aureus ; Microbial Sensitivity Tests ; Structure-Activity Relationship ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Use of Schisandrin B to Combat Triple-Negative Breast Cancers by Inhibiting NLRP3-Induced Interleukin-1β Production.
Autorzy:
Chang CM; Department of General Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.; School of Medicine, Tzu Chi University, Hualien 970374, Taiwan.
Liang TR; PhD Program in Pharmacology and Toxicology, Tzu Chi University, Hualien 970374, Taiwan.
Lam HYP; Department of Biochemistry, School of Medicine, Tzu Chi University, Hualien 970374, Taiwan.
Źródło:
Biomolecules [Biomolecules] 2024 Jan 05; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Triple Negative Breast Neoplasms*/drug therapy
Bile Duct Neoplasms*
Polycyclic Compounds*
Lignans*
Humans ; NLR Family, Pyrin Domain-Containing 3 Protein ; Interleukin-1beta ; Bile Ducts, Intrahepatic ; Cyclooctanes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Schizandrin A induces non-small cell lung cancer apoptosis by suppressing the epidermal growth factor receptor activation.
Autorzy:
Zhu L; Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wang Y; Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huang X; Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Liu X; Department of Arthropathy, Zhejiang University of Traditional Chinese Medicine Affiliated Integrated Chinese and Western Medicine Hospital, Hangzhou, China.
Ye B; Department of Thoracic Surgery, Hangzhou Red Cross Hospital, Hangzhou, China.
He Y; State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou, China.
Yu H; State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Lv W; Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wang L; Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hu J; Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.; Key Laboratory of Clinical Evaluation Technology for Medical device of Zhejiang Province, Hangzhou, China.
Źródło:
Cancer medicine [Cancer Med] 2024 Jan; Vol. 13 (2), pp. e6942.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Cyclooctanes*/pharmacology
Lignans*/pharmacology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Polycyclic Compounds*/pharmacology
Humans ; Apoptosis ; Cell Line, Tumor ; ErbB Receptors/genetics ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibitory effects of Schisandrin C on collagen behavior in pulmonary fibrosis.
Autorzy:
Xu M; Department of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China.
Zhao C; Department of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China.
Song H; Department of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China.
Wang C; Department of Pharmacology, College of Pharmacy, Beihua University, Jilin, China.
Li H; Department of Pharmacology, College of Pharmacy, Beihua University, Jilin, China.
Qiu X; Department of Hand Surgery, Affiliated Hospital, Beihua University, Jilin, China.
Jing H; Department of Hand Surgery, Affiliated Hospital, Beihua University, Jilin, China.
Zhuang W; Department of Molecular Biology Test Technique, College of Medical Technology, Beihua University, No. 3999 Binjiang East Road, Fengman District, Jilin, 132013, China. .
Źródło:
Scientific reports [Sci Rep] 2023 Aug 18; Vol. 13 (1), pp. 13475. Date of Electronic Publication: 2023 Aug 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pulmonary Fibrosis*/drug therapy
Lignans*/pharmacology
Lignans*/therapeutic use
Polycyclic Compounds*/pharmacology
Polycyclic Compounds*/therapeutic use
Animals ; Mice ; Collagen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessing Boron-Pleuromutilin AN11251 for the Development of Antibacterial Agents.
Autorzy:
Han MJ; Department of DMPK & Tox, Global Health Drug Discovery Institute, Zhongguancun Dongsheng International Science Park, Beijing 100192, China.
Pan M; Department of TB Biology, Global Health Drug Discovery Institute, Zhongguancun Dongsheng International Science Park, Beijing 100192, China.
Xiao G; Department of TB Biology, Global Health Drug Discovery Institute, Zhongguancun Dongsheng International Science Park, Beijing 100192, China.
Yuan Y; Department of TB Biology, Global Health Drug Discovery Institute, Zhongguancun Dongsheng International Science Park, Beijing 100192, China.
Chen S; Department of TB Biology, Global Health Drug Discovery Institute, Zhongguancun Dongsheng International Science Park, Beijing 100192, China.
Zou Z; Department of DMPK & Tox, Global Health Drug Discovery Institute, Zhongguancun Dongsheng International Science Park, Beijing 100192, China.
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 08; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:
Journal Article
MeSH Terms:
Diterpenes*/chemistry
Polycyclic Compounds*/pharmacology
Onchocerciasis*/drug therapy
Humans ; Anti-Bacterial Agents/chemistry ; Boron ; Bacteria ; Gram-Positive Bacteria ; Microbial Sensitivity Tests ; Pleuromutilins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design, Synthesis and Biological Evaluation of Novel Pleuromutilin Derivatives Containing 6-Chloro-1-R-1 H -pyrazolo[3,4- d ]pyrimidine-4-amino Side Chain.
Autorzy:
Wang J; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Hu YH; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Zhou KX; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Wang W; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Li F; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Li K; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Zhang GY; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.
Tang YZ; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou 510642, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 08; Vol. 28 (9). Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article
MeSH Terms:
Methicillin-Resistant Staphylococcus aureus*
Diterpenes*/chemistry
Polycyclic Compounds*/pharmacology
Staphylococcal Infections*/drug therapy
Animals ; Mice ; Humans ; Staphylococcus aureus ; Molecular Docking Simulation ; Caco-2 Cells ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/chemistry ; Pyrimidines/pharmacology ; Pyrimidines/chemistry ; Pleuromutilins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation, and molecular docking study.
Autorzy:
Aknin K; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Bontemps A; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Farce A; Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, Université de Lille, Lille, France.
Merlet E; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Belmont P; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Helissey P; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Chavatte P; Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, Université de Lille, Lille, France.
Sari MA; Faculté des Sciences, CNRS, UMR 8601, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Université de Paris, Paris, France.
Giorgi-Renault S; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Desbène-Finck S; Faculté de Santé, Faculté de Pharmacie de Paris, Cibles Thérapeutiques et Conception de Médicaments (CiTCoM), CNRS UMR8038, Université de Paris, Paris, France.
Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 252-268.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Docking Simulation*
Enzyme Inhibitors/*pharmacology
Heterocyclic Compounds/*pharmacology
Nitrogen/*pharmacology
Polycyclic Compounds/*pharmacology
Thymidine Phosphorylase/*antagonists & inhibitors
Cell Line ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Heterocyclic Compounds/chemical synthesis ; Heterocyclic Compounds/chemistry ; Humans ; Molecular Structure ; Nitrogen/chemistry ; Polycyclic Compounds/chemical synthesis ; Polycyclic Compounds/chemistry ; Structure-Activity Relationship ; Thymidine Phosphorylase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Stable and Unstable Concentration Oscillations Induced by Temperature Oscillations on Reversible Nonequilibrium Chemical Reactions of Helicene Oligomers.
Autorzy:
Zhang S; State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China.
Bao M; State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China.
Arisawa M; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan.
Yamaguchi M; State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 30; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polycyclic Compounds*
Temperature ; Catalysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Two-Step Synthesis, Structure, and Optical Features of a Double Hetero[7]helicene.
Autorzy:
Salem MSH; SANKEN, Osaka University, Ibaraki-shi, Osaka 567-0047, Japan.; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Sabri A; SANKEN, Osaka University, Ibaraki-shi, Osaka 567-0047, Japan.
Khalid MI; SANKEN, Osaka University, Ibaraki-shi, Osaka 567-0047, Japan.
Sasai H; SANKEN, Osaka University, Ibaraki-shi, Osaka 567-0047, Japan.; Graduate School of Pharmaceutical Sciences, Osaka University, Suita-shi, Osaka 565-0871, Japan.
Takizawa S; SANKEN, Osaka University, Ibaraki-shi, Osaka 567-0047, Japan.
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 19; Vol. 27 (24). Date of Electronic Publication: 2022 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Polycyclic Compounds*/chemistry
Molecular Structure ; Cyclization ; Crystallography, X-Ray
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Recent Advances in the Chemistry of Saturated Annulated Nitrogen-Containing Polycyclic Compounds.
Autorzy:
Kirsanov VY; Institute of Petrochemistry and Catalysis, Ufa Federal Research Center of Russian Academy of Sciences, Prospekt Oktyabrya 141, 450075 Ufa, Russia.
Rakhimova EB; Institute of Petrochemistry and Catalysis, Ufa Federal Research Center of Russian Academy of Sciences, Prospekt Oktyabrya 141, 450075 Ufa, Russia.
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 07; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polycyclic Compounds*
Heterocyclic Compounds*/chemistry
Nitrogen/chemistry ; Nitrogen Compounds ; Chemical Phenomena
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups.
Autorzy:
Wang Q; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Liu J; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zhou ZD; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zhou KX; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Li F; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zhang QW; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Wang SK; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Wang W; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Jin Z; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Tang YZ; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2078-2091.
Typ publikacji:
Journal Article
MeSH Terms:
Diterpenes*/chemistry
Diterpenes*/pharmacology
Methicillin-Resistant Staphylococcus aureus*
Polycyclic Compounds*/pharmacology
Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Mice ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Nitrogen/pharmacology ; Staphylococcus aureus ; Pleuromutilins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Oxidation of an Internal-Edge-Substituted [5]Helicene-Derived Phosphine Synchronously Enhances Circularly Polarized Luminescence.
Autorzy:
Usui K; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.; Graduate School of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.
Narita N; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Eto R; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Suzuki S; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Higashi-Osaka, Osaka, 577-8502, Japan.
Yokoo A; Graduate School of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.
Yamamoto K; Graduate School of Pharmaceutical Sciences, Kyushu University, Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.
Igawa K; Department of Chemistry, Faculty of Advanced Science and Technology, Kumamoto University, Kurokami 2-39-1, Kumamoto, 860-8555, Japan.
Iizuka N; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Mimura Y; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Higashi-Osaka, Osaka, 577-8502, Japan.
Umeno T; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Matsumoto S; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Hasegawa M; Graduate School of Science, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan.
Tomooka K; Institute for Materials Chemistry and Engineering, Kyushu University, Kasuga, Fukuoka, 816-8580, Japan.
Imai Y; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Higashi-Osaka, Osaka, 577-8502, Japan.
Karasawa S; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Nov 21; Vol. 28 (65), pp. e202203413. Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Luminescence*
Polycyclic Compounds*
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
QSPR Modeling and Experimental Determination of the Antioxidant Activity of Some Polycyclic Compounds in the Radical-Chain Oxidation Reaction of Organic Substrates.
Autorzy:
Khairullina V; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Martynova Y; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Safarova I; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Sharipova G; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Gerchikov A; Faculty of Chemistry, Bashkir State University, 450076 Ufa, Russia.
Limantseva R; Institute of Petrochemistry and Catalysis of the Ufa Federal Research Center of the Russian Academy of Sciences, 450075 Ufa, Russia.
Savchenko R; Institute of Petrochemistry and Catalysis of the Ufa Federal Research Center of the Russian Academy of Sciences, 450075 Ufa, Russia.
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Oct 02; Vol. 27 (19). Date of Electronic Publication: 2022 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Polycyclic Compounds*
Quantitative Structure-Activity Relationship*
Antioxidants/pharmacology ; Ecdysterone ; Hydrocarbons ; Phenols ; Sulfur
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vitro and In Vivo Antibacterial Activity, Toxicity and Resistance Analysis of Pleuromutilin Derivative Z33 against Methicillin-Resistant Staphylococcus aureus .
Autorzy:
Hu Y; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Chen F; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zhou K; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zhang Z; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Li F; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zhang J; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Tang Y; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.
Jin Z; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Aug 03; Vol. 27 (15). Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Diterpenes*/pharmacology
Diterpenes*/therapeutic use
Methicillin-Resistant Staphylococcus aureus*
Polycyclic Compounds*/pharmacology
Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Mice ; Microbial Sensitivity Tests ; Pleuromutilins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Quinoline- and Isoindoline-Integrated Polycyclic Compounds as Antioxidant, and Antidiabetic Agents Targeting the Dual Inhibition of α-Glycosidase and α-Amylase Enzymes.
Autorzy:
Al-Ghorbani, Mohammed (AUTHOR)
Alharbi, Osama (AUTHOR)
Al-Odayni, Abdel-Basit (AUTHOR)
Abduh, Naaser A. Y. (AUTHOR)
Źródło:
Pharmaceuticals (14248247). Sep2023, Vol. 16 Issue 9, p1222. 27p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design, synthesis and antibacterial activity evaluation of pleuromutilin derivatives according to twin drug theory.
Autorzy:
Liu HX; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Cui G; College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Ma DL; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.
Zhang Y; College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Xue FQ; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Źródło:
Journal of Asian natural products research [J Asian Nat Prod Res] 2022 Apr; Vol. 24 (4), pp. 371-387. Date of Electronic Publication: 2021 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Diterpenes*/pharmacology
Polycyclic Compounds*/pharmacology
Anti-Bacterial Agents/pharmacology ; Drug Design ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship ; Pleuromutilins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 3506

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