Temat: "pore-forming" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells.
Autorzy:: Rodríguez-Silvestre P; MRC Laboratory of Molecular Biology, Cambridge, UK.
Laub M; MRC Laboratory of Molecular Biology, Cambridge, UK.
Krawczyk PA; MRC Laboratory of Molecular Biology, Cambridge, UK.
Davies AK; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Schessner JP; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Parveen R; MRC Laboratory of Molecular Biology, Cambridge, UK.
Tuck BJ; MRC Laboratory of Molecular Biology, Cambridge, UK.; UK Dementia Research Institute at the University of Cambridge, Department of Clinical Neurosciences, Cambridge, UK.
McEwan WA; UK Dementia Research Institute at the University of Cambridge, Department of Clinical Neurosciences, Cambridge, UK.
Borner GHH; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Kozik P; MRC Laboratory of Molecular Biology, Cambridge, UK.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2023 Jun 23; Vol. 380 (6651), pp. 1258-1265. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:: Journal Article
MeSH Terms:: Antigen Presentation*
CD8-Positive T-Lymphocytes*/immunology
Endocytosis*/genetics
Endocytosis*/immunology
Pore Forming Cytotoxic Proteins*/genetics
Pore Forming Cytotoxic Proteins*/metabolism
Animals ; Mice ; Antigens/immunology ; Cross-Priming/genetics ; Cross-Priming/immunology ; Dendritic Cells/immunology ; Genetic Testing ; Histocompatibility Antigens Class I ; Proteolysis

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Skocz do pozycji: 2.

Tytuł:: Channeling antigens to CD8 T cells.
Autorzy:: Rawat K; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Jakubzick CV; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2023 Jun 23; Vol. 380 (6651), pp. 1218-1219. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:: Journal Article
MeSH Terms:: CD8-Positive T-Lymphocytes*/immunology
Dendritic Cells*/immunology
Endocytosis*/immunology
Pore Forming Cytotoxic Proteins*/metabolism
Animals ; Mice ; Antigens/immunology ; Cross-Priming

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Skocz do pozycji: 3.

Tytuł:: Down-regulation of KLF9 ameliorates LPS-caused acute lung injury and inflammation in mice via reducing GSDMD expression.
Autorzy:: Qu R; Department of Laboratory Medicine, Qishan Hospital, Yantai, Shandong, China.
Liu J; Department of Laboratory Medicine, Qishan Hospital, Yantai, Shandong, China.
Feng L; Department of Microbiology Laboratory, Huangdao District Center for Disease Control and Prevention, Qingdao, Shandong, China.
Li L; Health Center of Shuidao Town, Yantai, Shandong, China.
Liu J; Department of Laboratory Medicine, Qishan Hospital, Yantai, Shandong, China.
Sun F; Department of Laboratory Medicine, Yantaishan Hospital, Yantai, Shandong, China.
Sun L; Department of Laboratory Medicine, Yantaishan Hospital, Yantai, Shandong, China.; Pokaż więcej
Źródło:: Autoimmunity [Autoimmunity] 2022 Dec; Vol. 55 (8), pp. 587-596. Date of Electronic Publication: 2022 Aug 21.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Lung Injury*/chemically induced
Acute Lung Injury*/genetics
Acute Lung Injury*/metabolism
Kruppel-Like Transcription Factors*/genetics
Kruppel-Like Transcription Factors*/metabolism
Phosphate-Binding Proteins*/genetics
Phosphate-Binding Proteins*/metabolism
Pore Forming Cytotoxic Proteins*/genetics
Pore Forming Cytotoxic Proteins*/metabolism
Animals ; Cytokines/metabolism ; Down-Regulation ; Inflammation/genetics ; Inflammation/metabolism ; Lipopolysaccharides ; Lung/metabolism ; Mice ; RAW 264.7 Cells

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Skocz do pozycji: 4.

Tytuł:: GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases.
Autorzy:: Sala R; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Josep Carreras Research Institute, Barcelona, Spain.
Rioja-Blanco E; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; Josep Carreras Research Institute, Barcelona, Spain.
Serna N; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Institut de Biotecnologia I de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Departament de Genètica I de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Sánchez-García L; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Institut de Biotecnologia I de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Departament de Genètica I de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Álamo P; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Josep Carreras Research Institute, Barcelona, Spain.
Alba-Castellón L; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; Josep Carreras Research Institute, Barcelona, Spain.
Casanova I; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Josep Carreras Research Institute, Barcelona, Spain.
López-Pousa A; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Department of Medical Oncology, Hospital de la Santa Creu I Sant Pau, Barcelon, Spain.
Unzueta U; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Josep Carreras Research Institute, Barcelona, Spain.
Céspedes MV; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.
Vázquez E; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Institut de Biotecnologia I de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Departament de Genètica I de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Villaverde A; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Institut de Biotecnologia I de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Departament de Genètica I de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Mangues R; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.; CIBER en Bioingeniería, Biomateriales Y Nanomedicina (CIBER-BBN), Madrid, Spain.; Josep Carreras Research Institute, Barcelona, Spain.; Pokaż więcej
Źródło:: Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 1384-1397.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Colorectal Neoplasms*/drug therapy
Phosphate-Binding Proteins*/metabolism
Pore Forming Cytotoxic Proteins*/metabolism
Pyroptosis*
Receptors, CXCR4*/metabolism
Receptors, CXCR4*/therapeutic use
Drug Delivery Systems ; Humans ; Neoplasm Metastasis/prevention & control ; Signal Transduction

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Skocz do pozycji: 5.

Tytuł:: Circ-USP9X interacts with EIF4A3 to promote endothelial cell pyroptosis by regulating GSDMD stability in atherosclerosis.
Autorzy:: Xu S; Department of Cardiology, Suzhou Science and Technology City Hospital, Suzhou, China.
Ge Y; Department of Cardiology, Suzhou Science and Technology City Hospital, Suzhou, China.
Wang X; Department of Cardiology, Suzhou Science and Technology City Hospital, Suzhou, China.
Yin W; Department of Cardiology, Suzhou Science and Technology City Hospital, Suzhou, China.
Zhu X; Department of Cardiology, Suzhou Science and Technology City Hospital, Suzhou, China.
Wang J; Department of Cardiology, Suzhou Science and Technology City Hospital, Suzhou, China.
Qiao S; Institute of clinical medicine, Suzhou Science and Technology City Hospital, Suzhou, China.; Pokaż więcej
Źródło:: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2023 Dec 31; Vol. 45 (1), pp. 2186319.
Typ publikacji:: Journal Article
MeSH Terms:: Atherosclerosis*/genetics
MicroRNAs*
Humans ; Apoptosis ; Cell Proliferation ; DEAD-box RNA Helicases ; Enzyme-Linked Immunosorbent Assay ; Eukaryotic Initiation Factor-4A ; Human Umbilical Vein Endothelial Cells ; L-Lactate Dehydrogenase ; Lipoproteins, LDL/pharmacology ; Phosphate-Binding Proteins/genetics ; Pore Forming Cytotoxic Proteins ; Pyroptosis

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Skocz do pozycji: 6.

Tytuł:: Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer.
Autorzy:: Xie W; Translational medicine centre, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, P. R. China.; Department of Hepatobiliary Surgery, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, P. R. China.
Peng M; Central laboratory, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, 410013, P. R. China.
Liu Y; Hunan Provincial Clinical Research Centre for Oncoplastic Surgery, Hunan Cancer hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, Hunan, 410013, P. R. China.
Zhang B; Translational medicine centre, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, P. R. China.; Hunan Provincial Clinical Research Centre for Oncoplastic Surgery, Hunan Cancer hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, Hunan, 410013, P. R. China.
Yi L; Hunan Provincial Clinical Research Centre for Oncoplastic Surgery, Hunan Cancer hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, Hunan, 410013, P. R. China.
Long Y; Translational medicine centre, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, P. R. China. .; Hunan Provincial Clinical Research Centre for Oncoplastic Surgery, Hunan Cancer hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, Hunan, 410013, P. R. China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2023 Nov 16; Vol. 21 (1), pp. 329. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:: Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Pyroptosis*
Colonic Neoplasms*/pathology
Mice ; Animals ; Humans ; Caspase 1/metabolism ; Reactive Oxygen Species/metabolism ; Simvastatin/pharmacology ; Mice, Nude ; HCT116 Cells ; Disease Models, Animal ; Phosphate-Binding Proteins/metabolism ; Pore Forming Cytotoxic Proteins/metabolism

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Skocz do pozycji: 7.

Tytuł:: System analysis based on the pyroptosis-related genes identifes GSDMD as a novel therapy target for skin cutaneous melanoma.
Autorzy:: Zhao S; Department of Burns, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Zhu Y; Department of Burns, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Liu H; Department of Burns, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
He X; Department of Burns, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Xie J; Department of Burns, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China. .; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2023 Nov 10; Vol. 21 (1), pp. 801. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Melanoma*/drug therapy
Melanoma*/genetics
Skin Neoplasms*/drug therapy
Skin Neoplasms*/genetics
Humans ; Pyroptosis/genetics ; Skin ; Biomarkers, Tumor/genetics ; Pore Forming Cytotoxic Proteins ; Phosphate-Binding Proteins/genetics ; Melanoma, Cutaneous Malignant

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Skocz do pozycji: 8.

Tytuł:: Gasdermin D Deficiency Does Not Protect Mice from High-Fat Diet-Induced Glucose Intolerance and Adipose Tissue Inflammation.
Autorzy:: Ma EB; College of Pharmacy, Chonnam National University, Gwangju, Republic of Korea.
Javaid HMA; College of Pharmacy, Chonnam National University, Gwangju, Republic of Korea.
Jung DH; Laboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Park JH; Laboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea.
Huh JY; College of Pharmacy, Chonnam National University, Gwangju, Republic of Korea.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2022 Aug 26; Vol. 2022, pp. 7853482. Date of Electronic Publication: 2022 Aug 26 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Adipose Tissue*/metabolism
Adipose Tissue*/pathology
Diet, High-Fat*/adverse effects
Glucose Intolerance*/metabolism
Phosphate-Binding Proteins*/genetics
Pore Forming Cytotoxic Proteins*/genetics
Animals ; Inflammasomes/metabolism ; Inflammation/metabolism ; Mice ; Mice, Knockout ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Obesity/metabolism ; PPAR gamma/metabolism

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Skocz do pozycji: 9.

Tytuł:: Translocation of gasdermin D induced mitochondrial injury and mitophagy mediated quality control in lipopolysaccharide related cardiomyocyte injury.
Autorzy:: Yu Z; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Department of Cardiovascular Diseases, Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Xiao Z; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Graduate School, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Guan L; Department of Cardiovascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, P. R. China.
Bao P; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Graduate School, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Yu Y; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Department of Cardiovascular Diseases, Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Liang Y; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Li M; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Department of Cardiovascular Diseases, Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Huang Z; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Chen X; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Chen R; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Department of Cardiovascular Diseases, Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Su Y; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Ge J; Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2022 Aug; Vol. 12 (8), pp. e1002.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Heart Diseases*
Mitochondria*/pathology
Mitophagy*
Myocytes, Cardiac*/drug effects
Phosphate-Binding Proteins*/genetics
Pore Forming Cytotoxic Proteins*/genetics
Humans ; Inflammation ; Lipopolysaccharides ; Mitochondrial Permeability Transition Pore ; Nigericin ; Quality Control

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Skocz do pozycji: 10.

Tytuł:: Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Autorzy:: Wu DM; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
He M; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Zhao YY; School of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Deng SH; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Liu T; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Zhang T; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Zhang F; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Wang YY; School of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Xu Y; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, People's Republic of China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2022 Jun 27; Vol. 20 (1), pp. 98. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:: Journal Article; Video-Audio Media; Research Support, Non-U.S. Gov't
MeSH Terms:: Aspergillosis*/metabolism
Epithelial Cells*/microbiology
Inflammasomes*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Phosphate-Binding Proteins*/metabolism
Pore Forming Cytotoxic Proteins*/metabolism
Animals ; Aspergillus fumigatus/metabolism ; Disease Models, Animal ; Disease Susceptibility/microbiology ; Lung/metabolism ; Mice ; Pyroptosis ; Whole-Body Irradiation

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Skocz do pozycji: 11.

Tytuł:: Identification of a novel DFNA5 mutation, IVS7-2 a > G, in a Chinese family with non-syndromic sensorineural hearing loss.
Autorzy:: Jin Z; Aerospace Balance Medical Center, Chinese PLA Air Forch General Hospital, Beijing, China.
Zhu Q; Department of Otolaryngology, Second Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
Lu Y; Medical Genetics Center, First Affiliated Hospital of Army Medical University, ChongQing, China.
Cheng J; Medical Genetics Center, First Affiliated Hospital of Army Medical University, ChongQing, China.
Yuan H; Medical Genetics Center, First Affiliated Hospital of Army Medical University, ChongQing, China.
Han D; Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China.; Pokaż więcej
Źródło:: Acta oto-laryngologica [Acta Otolaryngol] 2022 May; Vol. 142 (5), pp. 448-453. Date of Electronic Publication: 2022 May 31.
Typ publikacji:: Journal Article
MeSH Terms:: Hearing Loss*/genetics
Hearing Loss, Sensorineural*/genetics
Pore Forming Cytotoxic Proteins*/genetics
Humans ; China ; Deafness/genetics ; Mutation ; Pedigree ; Receptors, Estrogen/genetics
SCR Disease Name:: Deafness, Autosomal Dominant 5; Nonsyndromic Deafness

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Skocz do pozycji: 12.

Tytuł:: ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer.
Autorzy:: Su P; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Mao X; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Ma J; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Huang L; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Yu L; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Tang S; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Zhuang M; College of Biological Science and Engineering, Fuzhou University, Fuzhou, 350108, Fujian, China.
Lu Z; College of Biological Science and Engineering, Fuzhou University, Fuzhou, 350108, Fujian, China.
Osafo KS; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Ren Y; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Wang X; Medical Research Center, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; NHC Key Laboratory of Technical Evaluation of Fertility Regulation for Non-Human Primate, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.
Lin X; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Huang L; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China.; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China.
Huang X; Department of Obstetrics and Gynecology, The First Affiliated Hospital, Fujian Medical University, FuzhouFujian, 350005, China.
Braicu EI; Department of Gynecology and Obstetrics, Charité Virchow University Hospital, Augustenberger Platz1, 13353, Berlin, Germany.
Sehouli J; Department of Gynecology and Obstetrics, Charité Virchow University Hospital, Augustenberger Platz1, 13353, Berlin, Germany.
Sun P; Laboratory of Gynecologic Oncology, Department of Gynecology, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China. .; Fujian Key Laboratory of Women and Children's Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China. .; Fujian Clinical Research Center for Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fuzhou, 350001, Fujian, China. .; National Key Clinical Specialty Construction Program of China (Gynecology), Fujian Maternity and Child Health Hospital, Fuzhou, 350001, Fujian, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Oct 20; Vol. 42 (1), pp. 274. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:: Journal Article
MeSH Terms:: NLR Family, Pyrin Domain-Containing 3 Protein*/genetics
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Endometrial Neoplasms*/drug therapy
Endometrial Neoplasms*/genetics
Humans ; Mice ; Animals ; Female ; Caspase 1/genetics ; Caspase 1/metabolism ; Caspase 1/pharmacology ; Mice, Nude ; Pyroptosis ; Cisplatin/pharmacology ; Glycolysis ; Tumor Microenvironment ; Phosphate-Binding Proteins/genetics ; Phosphate-Binding Proteins/metabolism ; Phosphate-Binding Proteins/pharmacology ; Pore Forming Cytotoxic Proteins/metabolism ; ERRalpha Estrogen-Related Receptor

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Skocz do pozycji: 13.

Tytuł:: METTL14-upregulated miR-6858 triggers cell apoptosis in keratinocytes of oral lichen planus through decreasing GSDMC.
Autorzy:: Wang X; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.; Department of Child Dental and Preventive Dentistry, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Li S; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Song H; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.; Department of Child Dental and Preventive Dentistry, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Ding Y; Department of Dermatology, Hainan Provincial Hospital of Skin Disease, Haikou, Hainan, China.; Department of Dermatology, Skin Disease Hospital of Hainan Medical University, Haikou, Hainan, China.
Gao R; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Shi X; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.; Department of Child Dental and Preventive Dentistry, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Li R; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Ge X; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2023 Sep 23; Vol. 6 (1), pp. 976. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Lichen Planus, Oral*/genetics
Lichen Planus, Oral*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; NF-kappa B/metabolism ; Keratinocytes/metabolism ; Apoptosis ; Biomarkers, Tumor/metabolism ; Pore Forming Cytotoxic Proteins/metabolism ; Methyltransferases/metabolism

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Skocz do pozycji: 14.

Tytuł:: GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice.
Autorzy:: Challa NVD; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Chen S; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Yuan H; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Duncan MR; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Moreno WJ; Miami Project to Cure Paralysis and Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Bramlett H; Miami Project to Cure Paralysis and Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Dietrich WD; Miami Project to Cure Paralysis and Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Benny M; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Schmidt AF; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Young K; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA.
Wu S; Department of Pediatrics/Division of Neonatology, Batchelor Children's Research Institute, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL, USA. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2023 Sep 07; Vol. 20 (1), pp. 205. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:: Journal Article
MeSH Terms:: Brain Injuries*
Hyperoxia*/complications
Animals ; Humans ; Infant, Newborn ; Mice ; Animals, Newborn ; Gene Knockout Techniques ; Hippocampus ; Infant, Premature ; Mice, Knockout ; Phosphate-Binding Proteins ; Pore Forming Cytotoxic Proteins

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Skocz do pozycji: 15.

Tytuł:: Gasdermin D (GSDMD) Is Upregulated in Psoriatic Skin-A New Potential Link in the Pathogenesis of Psoriasis.
Autorzy:: Nowowiejska J; Department of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St., 15-540 Bialystok, Poland.
Baran A; Department of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St., 15-540 Bialystok, Poland.
Hermanowicz JM; Department of Pharmacodynamics, Medical University of Bialystok, Mickiewicza 2C St., 15-089 Bialystok, Poland.
Pryczynicz A; Department of General Pathomorphology, Medical University of Bialystok, 13 Waszyngtona St., 15-269 Bialystok, Poland.
Sieklucka B; Department of Pharmacodynamics, Medical University of Bialystok, Mickiewicza 2C St., 15-089 Bialystok, Poland.
Pawlak D; Department of Pharmacodynamics, Medical University of Bialystok, Mickiewicza 2C St., 15-089 Bialystok, Poland.
Flisiak I; Department of Dermatology and Venereology, Medical University of Bialystok, Zurawia 14 St., 15-540 Bialystok, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 22; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:: Journal Article
MeSH Terms:: Psoriasis*/genetics
Body Fluids*
Humans ; Gasdermins ; Skin ; Cell Proliferation ; Phosphate-Binding Proteins/genetics ; Pore Forming Cytotoxic Proteins

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Skocz do pozycji: 16.

Tytuł:: Oridonin Relieves Angiotensin II-Induced Cardiac Remodeling via Inhibiting GSDMD-Mediated Inflammation.
Autorzy:: Lin S; The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Dai S; Department of Emergency, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lin J; Wenzhou Medical University, Wenzhou, Zhejiang, China.
Liang X; The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Wang W; The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Huang W; The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ye B; The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Hong X; The Key Laboratory of Cardiovascular Disease of Wenzhou, Department of Cardiac Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Pokaż więcej
Źródło:: Cardiovascular therapeutics [Cardiovasc Ther] 2022 Mar 14; Vol. 2022, pp. 3167959. Date of Electronic Publication: 2022 Mar 14 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Angiotensin II*
Phosphate-Binding Proteins*/metabolism
Pore Forming Cytotoxic Proteins*/metabolism
Ventricular Remodeling*
Animals ; Diterpenes, Kaurane ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/prevention & control ; Intracellular Signaling Peptides and Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Myocytes, Cardiac ; Rats

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Skocz do pozycji: 17.

Tytuł:: A deep learning model to detect novel pore-forming proteins.
Autorzy:: Jacob T; BASF Corporation, 3500 Paramount Parkway, Morrisville, NC, 27560, USA. .
Kahn TW; BASF Corporation, 3500 Paramount Parkway, Morrisville, NC, 27560, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Feb 07; Vol. 12 (1), pp. 2013. Date of Electronic Publication: 2022 Feb 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Deep Learning*
Pesticides*
Pore Forming Cytotoxic Proteins/*analysis
Amino Acid Sequence ; Bacteria/metabolism ; Bacteria/pathogenicity ; Crops, Agricultural ; Pore Forming Cytotoxic Proteins/chemistry

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Skocz do pozycji: 18.

Tytuł:: Perforin affects regeneration in a mouse spinal cord injury model.
Autorzy:: Jakovcevski I; Center for Molecular Neurobiology Hamburg, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Schachner M; Center for Molecular Neurobiology Hamburg, University Hospital Hamburg-Eppendorf, Hamburg, Germany.; Center for Neuroscience, Shantou University Medical College, Shantou, Guangdong, China.; Keck Center for Collaborative Neuroscience and Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.; Pokaż więcej
Źródło:: The International journal of neuroscience [Int J Neurosci] 2022 Jan; Vol. 132 (1), pp. 1-12. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Locomotion/*physiology
Nerve Regeneration/*physiology
Pore Forming Cytotoxic Proteins/*physiology
Spinal Cord Injuries/*enzymology
Spinal Cord Injuries/*immunology
Spinal Cord Injuries/*physiopathology
Animals ; Behavior, Animal/physiology ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred C57BL ; Pore Forming Cytotoxic Proteins/deficiency

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Skocz do pozycji: 19.

Tytuł:: Upregulated GSDMB in Clear Cell Renal Cell Carcinoma Is Associated with Immune Infiltrates and Poor Prognosis.
Autorzy:: Cui Y; Department of Urology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.; Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, China.
Zhou Z; Department of Urology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
Chai Y; Department of Urology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
Zhang Y; Department of Urology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2021 Dec 16; Vol. 2021, pp. 7753553. Date of Electronic Publication: 2021 Dec 16 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Carcinoma, Renal Cell/*etiology
Carcinoma, Renal Cell/*mortality
Kidney Neoplasms/*etiology
Kidney Neoplasms/*mortality
Pore Forming Cytotoxic Proteins/*genetics
Biomarkers, Tumor ; Carcinoma, Renal Cell/diagnosis ; Carcinoma, Renal Cell/metabolism ; Computational Biology/methods ; Databases, Genetic ; Gene Expression Profiling ; Humans ; Kaplan-Meier Estimate ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/metabolism ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Molecular Sequence Annotation ; Multivariate Analysis ; Pore Forming Cytotoxic Proteins/metabolism ; Prognosis ; Protein Interaction Mapping ; ROC Curve ; Tumor-Associated Macrophages/immunology ; Tumor-Associated Macrophages/metabolism ; Tumor-Associated Macrophages/pathology

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Skocz do pozycji: 20.

Tytuł:: Establishment and validation of a gasdermin signature to evaluate the immune status and direct risk-group classification in luminal-B breast cancer.
Autorzy:: Yang C; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu J; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhao S; Department of Thoracic Surgery, Beijing Tuberculosis and Thoracic Tumor Research Institute/Beijing Chest Hospital, Capital Medical University, Beijing, China.
Ying J; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu Y; Department of Pathology, The Fourth Hospital of Hebei Medical University, Hebei, China.
Ma L; Breast Center, The Fourth Hospital of Hebei Medical University, Hebei, China.
Shang Q; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Meng X; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Feng K; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zheng B; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Guo C; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang X; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang X; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2021 Nov; Vol. 11 (11), pp. e614.
Typ publikacji:: Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers, Tumor/*analysis
Breast Neoplasms/*diagnosis
Pore Forming Cytotoxic Proteins/*analysis
Risk Assessment/*trends
BRCA2 Protein/genetics ; BRCA2 Protein/metabolism ; Biomarkers, Tumor/genetics ; Breast Neoplasms/complications ; Breast Neoplasms/genetics ; Female ; Humans ; Pore Forming Cytotoxic Proteins/genetics ; Proportional Hazards Models ; Risk Assessment/methods ; Risk Assessment/standards ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism

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