Temat: "proliferation" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Cancer Drug Resistance: Targeting Proliferation or Programmed Cell Death.
Autorzy:: Sazonova EV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.
Yapryntseva MA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.
Pervushin NV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.
Tsvetcov RI; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.
Zhivotovsky B; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institute, P.O. Box 210, 17177 Stockholm, Sweden.
Kopeina GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Feb 23; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Neoplasms*
Drug Resistance, Neoplasm ; Apoptosis ; Cell Death ; Cell Proliferation

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Skocz do pozycji: 2.

Tytuł:: Noscapine and Apoptosis in Breast and Other Cancers.
Autorzy:: Calaf GM; Instituto de Alta Investigación, Universidad de Tarapacá, Arica 1000000, Chile.
Crispin LA; Instituto de Alta Investigación, Universidad de Tarapacá, Arica 1000000, Chile.
Quisbert-Valenzuela EO; Instituto de Alta Investigación, Universidad de Tarapacá, Arica 1000000, Chile.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 21; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Noscapine*/pharmacology
Glioblastoma*
Antineoplastic Agents*/pharmacology
Breast Neoplasms*/pathology
Male ; Female ; Humans ; bcl-2-Associated X Protein/metabolism ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Proliferation

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Skocz do pozycji: 3.

Tytuł:: The Transcriptome of BT-20 Breast Cancer Cells Exposed to Curcumin Analog NC2603 Reveals a Relationship between EGR3 Gene Modulation and Cell Migration Inhibition.
Autorzy:: Nishimura FG; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Sampaio BB; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
do Couto GO; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
da Silva AD; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
da Silva WJ; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Peronni KC; Instituto para Pesquisa do Cancêr (IPEC), Guarapuava 85100-000, Brazil.
Evangelista AF; Sergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Manguinhos, Rio de Janeiro 21041-210, Brazil.
Hossain M; School of Sciences, Indiana University Kokomo, Kokomo, IN 46904, USA.
Dimmock JR; College of Pharmacy and Nutrition, University of Saskatchewan (USask), Saskatoon, SK S7N 5E5, Canada.
Bandy B; College of Pharmacy and Nutrition, University of Saskatchewan (USask), Saskatoon, SK S7N 5E5, Canada.
Beleboni RO; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Marins M; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Fachin AL; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 19; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:: Journal Article
MeSH Terms:: Curcumin*
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Female ; Cell Migration Inhibition ; Transcriptome ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Apoptosis ; Early Growth Response Protein 3/metabolism ; Early Growth Response Protein 3/pharmacology

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Skocz do pozycji: 4.

Tytuł:: Cytotoxic Tph subset with low B-cell helper functions and its involvement in systemic lupus erythematosus.
Autorzy:: Seki N; Research Unit Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan.; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Tsujimoto H; Research Unit Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan.; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Tanemura S; Research Unit Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan.; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Kojima S; Discovery Technology Laboratories, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan.
Miyoshi F; Discovery Technology Laboratories, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan.
Kikuchi J; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Saito S; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Akiyama M; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Sugahara K; Research Unit Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan.; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Yoshimoto K; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Kaneko Y; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Chiba K; Research Unit Immunology & Inflammation, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama-shi, Kanagawa, Japan. .; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan. .
Takeuchi T; Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.; Saitama Medical University, Iruma-gun, Saitama, Japan.; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2024 Mar 06; Vol. 7 (1), pp. 277. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:: Journal Article
MeSH Terms:: Lupus Erythematosus, Systemic*/genetics
Lupus Nephritis*
Antineoplastic Agents*
Humans ; Cell Cycle ; Cell Proliferation

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Skocz do pozycji: 5.

Tytuł:: Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3- d ][1,2,4]triazolo[1,5- a ]pyrimidine Derivatives.
Autorzy:: Elsenbawy ESM; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
Alshehri ZS; Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Dawadmi 19257, Saudi Arabia.
Babteen NA; Department of Biochemistry, College of Sciences, University of Jeddah, Jeddah 21577, Saudi Arabia.
Abdel-Rahman AA; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
El-Manawaty MA; Department of Pharmacognosy, Pharmaceutical Science Division, National Research Centre, Cairo 12622, Egypt.
Nossier ES; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.
Arafa RK; Drug Design and Discovery Laboratory, Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Ahmed Zewail Road, October Gardens, Cairo 12578, Egypt.
Hassan NA; Synthetic Unit, Department of Photochemistry, Chemical Industries Research Institute, National Research Centre, Cairo 12622, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 29; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Humans ; Molecular Structure ; Structure-Activity Relationship ; Molecular Docking Simulation ; Pyrimidines/pharmacology ; Triazoles/pharmacology ; Drug Screening Assays, Antitumor ; Cell Proliferation ; Cell Line, Tumor ; Drug Design

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Skocz do pozycji: 6.

Tytuł:: ELK1/MTOR/S6K1 Pathway Contributes to Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer.
Autorzy:: Zhao L; Department of Pathology and Genomic Medicine, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Wang Y; Department of Pathology and Genomic Medicine, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Sun X; Department of Pathology and Genomic Medicine, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Zhang X; Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Simone N; Department of Radiation Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.
He J; Department of Pathology and Genomic Medicine, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 17; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
ets-Domain Protein Elk-1*
Gefitinib*/pharmacology
Gefitinib*/therapeutic use
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Tyrosine Kinase Inhibitors*/pharmacology
Tyrosine Kinase Inhibitors*/therapeutic use
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/metabolism ; Mice, Nude ; Ribosomal Protein S6 Kinases ; RNA, Small Interfering/pharmacology ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/metabolism

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Skocz do pozycji: 7.

Tytuł:: Synthesis and Biological Evaluation of Novel Amino and Amido Substituted Pentacyclic Benzimidazole Derivatives as Antiproliferative Agents.
Autorzy:: Perin N; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Gulin M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Kos M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Persoons L; KU Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute, 3000 Leuven, Belgium.
Daelemans D; KU Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute, 3000 Leuven, Belgium.
Fabijanić I; Ruđer Bošković Institute, Division of Organic Chemistry and Biochemistry, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Stojković MR; Ruđer Bošković Institute, Division of Organic Chemistry and Biochemistry, Bijenička cesta 54, HR-10000 Zagreb, Croatia.
Hranjec M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/chemistry
Humans ; Structure-Activity Relationship ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Benzimidazoles/chemistry ; Cell Proliferation ; Molecular Structure

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Skocz do pozycji: 8.

Tytuł:: Synthesis and Antitumor Activity Evaluation of Novel Echinatin Derivatives with a 1,3,4-Oxadiazole Moiety.
Autorzy:: Tian X; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Sun Z; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhong Y; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yang H; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Cheng M; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Liu Y; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/chemistry
Neoplasms*
Oxadiazoles*
Chalcones*
Humans ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Docking Simulation ; Cell Proliferation ; Molecular Structure ; Cell Line, Tumor ; Dose-Response Relationship, Drug

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Skocz do pozycji: 9.

Tytuł:: Synthesis and In Vitro Antitumor Activity Evaluation of Gefitinib-1,2,3-Triazole Derivatives.
Autorzy:: Liu Z; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China.
Liu J; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China.
Gao E; School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China.
Mao L; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China.
Hu S; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China.
Li S; College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 13; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: Lung Neoplasms*/drug therapy
Antineoplastic Agents*/chemistry
Humans ; Gefitinib/pharmacology ; Cell Proliferation ; Cell Line, Tumor ; Apoptosis ; Triazoles/pharmacology ; Triazoles/therapeutic use ; Drug Screening Assays, Antitumor ; Structure-Activity Relationship

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Skocz do pozycji: 10.

Tytuł:: Discovery of A Novel Series of Quinazoline-Thiazole Hybrids as Potential Antiproliferative and Anti-Angiogenic Agents.
Autorzy:: Șandor A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.
Fizeșan I; Department of Toxicology, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012 Cluj-Napoca, Romania.
Ionuț I; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.
Marc G; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.
Moldovan C; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.
Oniga I; Department of Pharmacognosy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 12 Ion Creangă Street, 400010 Cluj-Napoca, Romania.
Pîrnău A; National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donath Street, 400293 Cluj-Napoca, Romania.
Vlase L; Department of Pharmaceutical Technology and Biopharmaceutics, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babeș, Street, 400012 Cluj-Napoca, Romania.
Petru AE; Department of Toxicology, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012 Cluj-Napoca, Romania.
Macasoi I; Department of Toxicology, Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.; Research Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.
Oniga O; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babes, Street, 400010 Cluj-Napoca, Romania.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Feb 12; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Sorafenib/pharmacology ; Molecular Docking Simulation ; Quinazolines/pharmacology ; Quinazolines/chemistry ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry ; Angiogenesis Inhibitors/pharmacology ; Cell Proliferation ; Molecular Structure

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Skocz do pozycji: 11.

Tytuł:: Synthesis, Characterization, Antioxidant, and Anticancer Activity against Colon Cancer Cells of Some Cinnamaldehyde-Based Chalcone Derivatives.
Autorzy:: El-Atawy MA; Chemistry Department, Faculty of Science at Yanbu, Taibah University, Yanbu 46423, Saudi Arabia.; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.
Hanna DH; Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
Bashal AH; Chemistry Department, Faculty of Science at Yanbu, Taibah University, Yanbu 46423, Saudi Arabia.
Ahmed HA; Chemistry Department, Faculty of Science at Yanbu, Taibah University, Yanbu 46423, Saudi Arabia.; Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
Alshammari EM; Department of Chemistry, College of Sciences, University of Ha'il, Ha'il 55473, Saudi Arabia.
Hamed EA; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.
Aljohani AR; Chemistry Department, Faculty of Science at Yanbu, Taibah University, Yanbu 46423, Saudi Arabia.; Saudi Irrigation Organization (SIO), Al-Hassa 31982, Saudi Arabia.
Omar AZ; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Feb 12; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:: Journal Article
MeSH Terms:: Chalcones*/pharmacology
Chalcone*/pharmacology
Chalcone*/chemistry
Antineoplastic Agents*/chemistry
Colonic Neoplasms*/drug therapy
Acrolein/*analogs & derivatives
Humans ; Structure-Activity Relationship ; Antioxidants/pharmacology ; Cell Line, Tumor ; Caco-2 Cells ; Cell Proliferation ; Apoptosis ; Molecular Structure

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Skocz do pozycji: 12.

Tytuł:: Synthesis and molecular docking simulations of novel azepines based on quinazolinone moiety as prospective antimicrobial and antitumor hedgehog signaling inhibitors.
Autorzy:: Noser AA; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt. .
El-Barbary AA; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Salem MM; Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
El Salam HAA; Green Chemistry Department, National Research Centre, Dokki, GizaCairo, 12622, Egypt.
Shahien M; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 12; Vol. 14 (1), pp. 3530. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:: Journal Article
MeSH Terms:: Oxazepines*/pharmacology
Anti-Infective Agents*/pharmacology
Antineoplastic Agents*/chemistry
Structure-Activity Relationship ; Molecular Docking Simulation ; Hedgehog Proteins ; Quinazolinones/pharmacology ; Cell Proliferation ; Escherichia coli/metabolism ; Staphylococcus aureus/metabolism ; Glucan 1,3-beta-Glucosidase ; Prospective Studies ; Molecular Structure ; Drug Screening Assays, Antitumor

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Skocz do pozycji: 13.

Tytuł:: Antineoplastic Activity of 9″-Lithospermic Acid Methyl Ester in Glioblastoma Cells.
Autorzy:: Tzitiridou P; Neurosurgical Institute, University of Ioannina, 45500 Ioannina, Greece.
Zoi V; Neurosurgical Institute, University of Ioannina, 45500 Ioannina, Greece.
Papagrigoriou T; Laboratory of Pharmacognosy, Division of Pharmacognosy-Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Lazari D; Laboratory of Pharmacognosy, Division of Pharmacognosy-Pharmacology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Sioka C; Neurosurgical Institute, University of Ioannina, 45500 Ioannina, Greece.
Alexiou GA; Neurosurgical Institute, University of Ioannina, 45500 Ioannina, Greece.; Department of Neurosurgery, University of Ioannina, 45500 Ioannina, Greece.
Kyritsis AP; Neurosurgical Institute, University of Ioannina, 45500 Ioannina, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Benzofurans*/pharmacology
Brain Neoplasms*/drug therapy
Brain Neoplasms*/pathology
Depsides*
Animals ; Temozolomide/pharmacology ; Cell Proliferation ; Cell Line, Tumor ; Apoptosis

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Skocz do pozycji: 14.

Tytuł:: New Derivatives of 1-(3-Methyl-1-Benzofuran-2-yl)Ethan-1-one: Synthesis and Preliminary Studies of Biological Activity.
Autorzy:: Napiórkowska M; Chair and Department of Biochemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.
Kumaravel P; Chair and Department of Biochemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.
Amboo Mahentheran M; Chair and Department of Biochemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.
Kiernozek-Kalińska E; Department of Immunology, Faculty of Biology, University of Warsaw, 1 Miecznikowa Str., 02-096 Warsaw, Poland.
Grosicka-Maciąg E; Department of Biochemistry and Laboratory Diagnostic, Collegium Medicum Cardinal Stefan Wyszyński University, Kazimierza Wóycickiego 1 Str., 01-938 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-6*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Benzofurans*
Humans ; Reactive Oxygen Species/pharmacology ; Apoptosis ; K562 Cells ; Cell Line, Tumor ; Cell Proliferation ; Drug Screening Assays, Antitumor

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Skocz do pozycji: 15.

Tytuł:: Identification of New EGFR Inhibitors by Structure-Based Virtual Screening and Biological Evaluation.
Autorzy:: Wang S; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Xu X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Pan C; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Guo Q; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Li Q; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Wan S; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Li Z; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhang J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Wu X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 04; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/chemistry
Antineoplastic Agents*/isolation & purification
Antineoplastic Agents*/pharmacology
ErbB Receptors*/antagonists & inhibitors
Protein Kinase Inhibitors*/chemistry
Protein Kinase Inhibitors*/isolation & purification
Protein Kinase Inhibitors*/pharmacology
Humans ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Cell Line, Tumor ; Cell Proliferation ; Lung Neoplasms/drug therapy ; Molecular Docking Simulation ; Molecular Dynamics Simulation

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Skocz do pozycji: 16.

Tytuł:: The Effect of 4-(Dimethylamino)phenyl-5-oxopyrrolidines on Breast and Pancreatic Cancer Cell Colony Formation, Migration, and Growth of Tumor Spheroids.
Autorzy:: Kairytė K; Department of Organic Chemistry, Kaunas University of Technology, Radvilėnų Rd. 19, LT-50254 Kaunas, Lithuania.
Vaickelionienė R; Department of Organic Chemistry, Kaunas University of Technology, Radvilėnų Rd. 19, LT-50254 Kaunas, Lithuania.
Grybaitė B; Department of Organic Chemistry, Kaunas University of Technology, Radvilėnų Rd. 19, LT-50254 Kaunas, Lithuania.
Anusevičius K; Department of Organic Chemistry, Kaunas University of Technology, Radvilėnų Rd. 19, LT-50254 Kaunas, Lithuania.
Mickevičius V; Department of Organic Chemistry, Kaunas University of Technology, Radvilėnų Rd. 19, LT-50254 Kaunas, Lithuania.
Petrikaitė V; Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio Al. 7, LT-10257 Vilnius, Lithuania.; Faculty of Medicine, Lithuanian University of Health Sciences, A. Mickevičiaus 9, LT-44307 Kaunas, Lithuania.; Laboratory of Drug Targets Histopathology, Institute of Cardiology, Lithuanian University of Health Sciences, Sukilėlių Pr. 13, LT-50162 Kaunas, Lithuania.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 02; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/therapeutic use
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/pathology
Triple Negative Breast Neoplasms*/drug therapy
Humans ; Structure-Activity Relationship ; Cell Proliferation ; Hydrazones/pharmacology ; Pyrrolidinones/pharmacology ; Cell Line, Tumor

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Skocz do pozycji: 17.

Tytuł:: The inhibitory effect of apatinib on different small cell lung cancer cells and in lung cancer-bearing mice and patients.
Autorzy:: Liu M; Department of Pulmonary Medicine, Binzhou People's Hospital, Binzhou, Shandong, China.
Li H; Department of Pulmonary Medicine, Binzhou People's Hospital, Binzhou, Shandong, China.
Guo R; Department of Pulmonary Medicine, Binzhou People's Hospital, Binzhou, Shandong, China.
Yu X; Department of Pulmonary Medicine, Penglai Traditional Chinese Medicine Hospital, Yantai, Shandong, China.
Li Y; Department of Pulmonary Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.; Pokaż więcej
Źródło:: The clinical respiratory journal [Clin Respir J] 2024 Feb; Vol. 18 (2), pp. e13738.
Typ publikacji:: Journal Article
MeSH Terms:: Lung Neoplasms*/drug therapy
Small Cell Lung Carcinoma*/drug therapy
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Pyridines*
Humans ; Animals ; Mice ; Cell Line, Tumor ; Signal Transduction ; Cell Proliferation

Czasopismo naukowe

na półce

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Skocz do pozycji: 18.

Tytuł:: Novel pyridine bearing pentose moiety-based anticancer agents: design, synthesis, radioiodination and bioassessments.
Autorzy:: Mehany MM; Laboratory Department, Chemistry Unit, Police Hospital, Agouza, Cairo, Egypt.
Hammam OA; Pathology Department, Theodor Bilharz Research Institute, Giza, Egypt.
Selim AA; Labeled Compounds Department, Hot Laboratories Centre, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt. adli_a_.
Sayed GH; Heterocyclic Synthesis Lab., Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Anwer KE; Heterocyclic Synthesis Lab., Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2738. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Iodine Radioisotopes*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Animals ; Mice ; MCF-7 Cells ; Caco-2 Cells ; Cell Proliferation ; Pyridines/pharmacology ; Pyridines/chemistry ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Drug Design ; Molecular Docking Simulation

Czasopismo naukowe

na półce

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Skocz do pozycji: 19.

Tytuł:: BP-M345 as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity.
Autorzy:: Moreira J; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.
Silva PMA; UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.; 1H-TOXRUN-One Health Toxicology Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.
Castro E; UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.
Saraiva L; LAQV/REQUIMTE, Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Pinto M; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.
Bousbaa H; UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra 1317, 4585-116 Gandra, Portugal.
Cidade H; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 30; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:: Journal Article
MeSH Terms:: Antimitotic Agents*/pharmacology
Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/metabolism
Humans ; Mitosis ; Cell Proliferation ; Cell Cycle ; Spindle Apparatus/metabolism ; Apoptosis ; Cell Line, Tumor

Czasopismo naukowe

na półce

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Skocz do pozycji: 20.

Tytuł:: Vinorelbine Improves the Efficacy of Sorafenib against Hepatocellular Carcinoma: A Promising Therapeutic Approach.
Autorzy:: Ng WH; Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore 168583, Singapore.
Soo KC; Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, Singapore 168583, Singapore.
Huynh H; Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore 168583, Singapore.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Animals ; Mice ; Sorafenib/pharmacology ; Sorafenib/therapeutic use ; Vinorelbine/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Xenograft Model Antitumor Assays

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