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Tytuł:
Aliskiren-Loaded Nanoparticles Downregulate (Pro)renin Receptor and ACE Gene Expression in the Heart of Spontaneously Hypertensive Rats: Effect on NADPH Oxidase.
Autorzy:
Barta A; Institute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.
Cebova M; Institute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.
Kovac A; Institute of Neuroimunology, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.
Koneracka M; Institute of Experimental Physics, Slovak Academy of Sciences, 040 01 Kosice, Slovakia.
Zavisova V; Institute of Experimental Physics, Slovak Academy of Sciences, 040 01 Kosice, Slovakia.
Pechanova O; Institute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.; Institute of Pathophysiology, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 10; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Prorenin Receptor*
Nanoparticles*
Amides*
Fumarates*
Male ; Animals ; Rats ; Rats, Inbred SHR ; NADPH Oxidases/genetics ; Myocytes, Cardiac ; Polyenes ; Gene Expression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
(Pro)renin receptor mediates tubular epithelial cell pyroptosis in diabetic kidney disease via DPP4-JNK pathway.
Autorzy:
Xie S; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Song S; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Liu S; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Li Q; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Zou W; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Ke J; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Wang C; Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China. .; Guangdong Provincial Engineering Research Center of Molecular Imaging Center, The Fifth Affiliated Hospital Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jan 05; Vol. 22 (1), pp. 26. Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetic Nephropathies*/metabolism
Prorenin Receptor*/metabolism
Animals ; Humans ; Mice ; Diabetes Mellitus ; Dipeptidyl Peptidase 4 ; Epithelial Cells ; MAP Kinase Signaling System ; Pyroptosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic Ablation of Prorenin Receptor in the Rostral Ventrolateral Medulla Influences Blood Pressure and Hydromineral Balance in Deoxycorticosterone-Salt Hypertension.
Autorzy:
Mathieu NM; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Fekete EM; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Muskus PC; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Brozoski DT; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Lu KT; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Wackman KK; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Gomez J; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Fang S; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Reho JJ; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Comprehensive Rodent Metabolic Phenotyping Core, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Grobe CC; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Vazirabad I; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Mouradian GC Jr; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Hodges MR; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Segar JL; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Grobe JL; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Comprehensive Rodent Metabolic Phenotyping Core, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Sigmund CD; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Nakagawa P; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
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Źródło:
Function (Oxford, England) [Function (Oxf)] 2023 Aug 07; Vol. 4 (5), pp. zqad043. Date of Electronic Publication: 2023 Aug 07 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Desoxycorticosterone Acetate*
Hypertension*/genetics
Prorenin Receptor*/genetics
Animals ; Female ; Mice ; Blood Pressure ; Receptors, Cell Surface ; Renin/genetics ; Sodium Chloride ; Vasoconstrictor Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related?
Autorzy:
Graciela Baeza-Pérez, Lourdes
Cabrera-Becerra, Sandra Edith
Romero-Nava, Rodrigo
Ramos-Tovar, Erika
Elena Hernández-Campos, Maria
Pedro, López-Sánchez
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Źródło:
Iranian Journal of Basic Medical Sciences. May2024, Vol. 27 Issue 5, p621-629. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
(Pro)renin receptor and insulin signalling regulate cell proliferation in MCF-7 breast cancer cells.
Autorzy:
Sato S; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hirose T; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.; Division of Nephrology and Endocrinology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.; Division of Integrative Renal Replacement Therapy, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Ohba K; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
Watanabe F; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
Watanabe T; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
Minato K; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
Endo A; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.; Division of Nephrology and Endocrinology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Ito H; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.; Division of Nephrology and Endocrinology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Mori T; Division of Nephrology and Endocrinology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.; Division of Integrative Renal Replacement Therapy, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Takahashi K; Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Dec 05; Vol. 172 (6), pp. 355-363.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/metabolism
Prorenin Receptor*/metabolism
Humans ; Cell Proliferation ; Insulin/pharmacology ; Insulin/metabolism ; MCF-7 Cells ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells.
Autorzy:
Mohammad, Amro H. (AUTHOR)
Couture, Frédéric (AUTHOR)
Gamache, Isabelle (AUTHOR)
Chen, Owen (AUTHOR)
El-Assaad, Wissal (AUTHOR)
Abdel-Malak, Nelly (AUTHOR)
Kwiatkowska, Anna (AUTHOR)
Muller, William (AUTHOR)
Day, Robert (AUTHOR)
Teodoro, Jose G. (AUTHOR)
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Źródło:
PLoS ONE. 7/18/2023, Vol. 18 Issue 7, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
ATP6AP2 is robustly expressed in pancreatic β cells and neuroendocrine tumors, and plays a role in maintaining cellular viability.
Autorzy:
Taguchi T; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan. .
Kimura K; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Suzuki A; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Fujishima R; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Shimizu N; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Hoshiyama A; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Masaki T; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Inoue M; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.; Health Care Center, Kitasato University, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Kato Y; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Satomi T; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Takano K; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan.
Imada T; Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Sasaki S; Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Miyatsuka T; Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, 1-15-1 Kitazato, Minami-Ku, Sagamihara, Kanagawa, 252-0374, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 07; Vol. 13 (1), pp. 9260. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin-Secreting Cells*/metabolism
Insulinoma*/genetics
Insulinoma*/metabolism
Neuroendocrine Tumors*/genetics
Neuroendocrine Tumors*/metabolism
Vacuolar Proton-Translocating ATPases*/metabolism
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Mice ; Rats ; Animals ; Humans ; Cell Survival/genetics ; Receptors, Cell Surface/metabolism ; Prorenin Receptor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of a monoclonal antibody against (pro)renin receptor on gliomagenesis.
Autorzy:
Fujimori T; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan. .
Shibayama Y; Department of Pharmacology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Kanda T; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Suzuki K; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Ogawa D; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Ishikawa R; Department of Diagnostic Pathology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Kadota K; Department of Diagnostic Pathology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Matsunaga T; Department of Diagnostic Pathology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Tamiya T; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Nishiyama A; Department of Pharmacology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Miyake K; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 16; Vol. 13 (1), pp. 808. Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioma*/genetics
Mice ; Animals ; Humans ; Prorenin Receptor ; Antibodies, Monoclonal/metabolism ; Mice, Nude ; Cell Line, Tumor ; Wnt Signaling Pathway/genetics ; Cell Proliferation ; beta Catenin/metabolism ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota.
Autorzy:
Wang J; Department of Medical Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China. .; Zhejiang Provincial Clinical Research Center for Cancer, Hangzhou, 310009, Zhejiang, China. .; Cancer Center of Zhejiang University, Hangzhou, 310058, Zhejiang, China. .
Ding Y; Department of Medical Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China.; Zhejiang Provincial Clinical Research Center for Cancer, Hangzhou, 310009, Zhejiang, China.; Cancer Center of Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Li D; Department of Medical Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China.; Zhejiang Provincial Clinical Research Center for Cancer, Hangzhou, 310009, Zhejiang, China.; Cancer Center of Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Zhu N; Department of Medical Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China.; Zhejiang Provincial Clinical Research Center for Cancer, Hangzhou, 310009, Zhejiang, China.; Cancer Center of Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Nishiyama A; Department of Pharmacology, Faculty of Medicine, Kagawa University, Takamatsu, Kagawa, 761-0793, Japan.
Yuan Y; Department of Medical Oncology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences of Zhejiang Province), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China. .; Zhejiang Provincial Clinical Research Center for Cancer, Hangzhou, 310009, Zhejiang, China. .; Cancer Center of Zhejiang University, Hangzhou, 310058, Zhejiang, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Jan 03; Vol. 21 (1), pp. 2. Date of Electronic Publication: 2023 Jan 03.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gastrointestinal Microbiome*
Colorectal Neoplasms*/pathology
Animals ; Mice ; Prorenin Receptor ; Wnt3 Protein/genetics ; Wnt3 Protein/metabolism ; Ubiquitination ; Receptors, Cell Surface/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Blood Pressure Elevation of Tubular Specific (P)RR Transgenic Mice and Lethal Tubular Degeneration due to Possible Intracellular Interactions between (P)RR and Alternative Renin Products.
Autorzy:
Saigo S; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Kino T; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.; Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Uchida K; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Sugawara T; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Chen L; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Sugiyama M; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Azushima K; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Wakui H; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Tamura K; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
Ishigami T; Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 28; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Pressure/*physiology
Intracellular Space/*metabolism
Kidney Tubules/*pathology
Kidney Tubules/*physiopathology
Receptors, Cell Surface/*metabolism
Renin/*metabolism
Animals ; Body Weight ; Hydrogen-Ion Concentration ; Mice, Transgenic ; Models, Biological ; Organ Specificity ; Osmolar Concentration ; Phenotype ; Sodium/metabolism ; Systole ; Transgenes ; Urine ; Prorenin Receptor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Renal Expression and Localization of the Receptor for (Pro)renin and Its Ligands in Rodent Models of Diabetes, Metabolic Syndrome, and Age-Dependent Focal and Segmental Glomerulosclerosis.
Autorzy:
Iacobini, Carla
Vitale, Martina
Sentinelli, Federica
Haxhi, Jonida
Pugliese, Giuseppe
Menini, Stefano
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Temat:
FOCAL segmental glomerulosclerosis
GENE expression
METABOLIC syndrome
PRORENIN receptor
RENIN
ENDOTHELIN receptors
Źródło:
International Journal of Molecular Sciences; Feb2024, Vol. 25 Issue 4, p2217, 14p
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High glucose induces trafficking of prorenin receptor and stimulates profibrotic factors in the collecting duct.
Autorzy:
Gogulamudi VR; Department of Physiology, School of Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA.
Arita DY; Department of Physiology, School of Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA.
Bourgeois CRT; Department of Physiology, School of Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA.
Jorgensen J; Department of Physiology, School of Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA.
He J; Department of Biochemistry, Tulane University School of Medicine, New Orleans, USA.
Wimley WC; Department of Biochemistry, Tulane University School of Medicine, New Orleans, USA.
Satou R; Department of Physiology, School of Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA.
Gonzalez AA; Instituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaiso, Chile.
Prieto MC; Department of Physiology, School of Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA. .; Hypertension and Renal Center of Excellence, Tulane University School of Medicine, New Orleans, LA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jul 05; Vol. 11 (1), pp. 13815. Date of Electronic Publication: 2021 Jul 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Experimental/*genetics
Diabetic Nephropathies/*genetics
Glucose/*metabolism
Kidney Tubules, Collecting/*metabolism
Receptors, Cell Surface/*genetics
Animals ; Collagen/genetics ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Diabetic Nephropathies/metabolism ; Diabetic Nephropathies/pathology ; Disease Models, Animal ; Fibronectins/genetics ; Gene Expression Regulation/drug effects ; Humans ; Hyperglycemia/genetics ; Hyperglycemia/metabolism ; Hyperglycemia/pathology ; Kidney Tubules, Collecting/pathology ; Rats ; Transforming Growth Factor beta/genetics ; Prorenin Receptor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
(Pro)renin receptor antagonist PRO20 attenuates nephrectomy-induced nephropathy in rats via inhibition of intrarenal RAS and Wnt/β-catenin signaling.
Autorzy:
Wang Y; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Wang Y; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Xue K; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Wang H; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Zhou J; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Gao F; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Li C; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
Yang T; Department of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City, UT, USA.
Fang H; Key Laboratory of Applied Pharmacology in Universities of Shandong, Department of Pharmacology, School of Pharmacy, Weifang Medical University, Weifang, China.
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Źródło:
Physiological reports [Physiol Rep] 2021 Jun; Vol. 9 (11), pp. e14881.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Kidney Diseases/*drug therapy
Nephrectomy/*adverse effects
Peptide Fragments/*therapeutic use
Receptors, Cell Surface/*antagonists & inhibitors
Renin/*therapeutic use
Renin-Angiotensin System/*drug effects
Wnt Signaling Pathway/*genetics
Animals ; Blotting, Western ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Kidney Diseases/etiology ; Kidney Diseases/metabolism ; Kidney Diseases/pathology ; Male ; Peptide Fragments/pharmacology ; Rats ; Rats, Wistar ; Real-Time Polymerase Chain Reaction ; Renin/pharmacology ; Prorenin Receptor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sex differences in soluble prorenin receptor in patients with type 2 diabetes.
Autorzy:
Visniauskas B; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Arita DY; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Rosales CB; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Feroz MA; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Luffman C; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Accavitti MJ; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Dawkins G; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Hong J; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Curnow AC; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA.
Thethi TK; Department of Medicine, Endocrinology Division, Tulane University School of Medicine, New Orleans, LA, USA.; AdventHealth, Translational Research Institute, Orlando, FL, USA.
Lefante JJ; Department of Biostatistics and Data Science, School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Jaimes EA; Renal Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mauvais-Jarvis F; Department of Medicine, Endocrinology Division, Tulane University School of Medicine, New Orleans, LA, USA.; Southeast Louisiana Veterans Healthcare System, New Orleans, LA, USA.; Tulane Center of Excellence in Sex-Based Biology and Medicine, New Orleans, LA, USA.
Fonseca VA; Department of Medicine, Endocrinology Division, Tulane University School of Medicine, New Orleans, LA, USA.; Southeast Louisiana Veterans Healthcare System, New Orleans, LA, USA.
Prieto MC; Department of Physiology, Tulane University School of Medicine, 1430 Tulane Avenue, SL39, New Orleans, LA, 70112, USA. .; Tulane Hypertension and Renal Center of Excellence, Tulane University School of Medicine, New Orleans, LA, USA. .
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Źródło:
Biology of sex differences [Biol Sex Differ] 2021 May 01; Vol. 12 (1), pp. 33. Date of Electronic Publication: 2021 May 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*
Adult ; Female ; Humans ; Kidney Diseases ; Male ; Middle Aged ; Receptors, Cell Surface ; Renin ; Sex Characteristics ; Prorenin Receptor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Recent Advances in Soluble Prorenin Receptor in Multisystem Diseases
Autorzy:
LI Mengye, JIANG Yinong
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Temat:
nephrosis
renin
renin-angiotensin system
cardiovascular diseases
soluble prorenin receptor
multisystem diseases
review
Medicine
Źródło:
Zhongguo quanke yixue, Vol 27, Iss 18, Pp 2295-2300 (2024)
Opis pliku:
electronic resource
Relacje:
https://www.chinagp.net/fileup/1007-9572/PDF/zx20220503.pdf; https://doaj.org/toc/1007-9572
Dostęp URL:
https://doaj.org/article/5c17b7828364472a89b6ee0e5328d8c3  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 760

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