Temat: "protein p53" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: P53 and BCL-2 family proteins PUMA and NOXA define competitive fitness in pluripotent cell competition.
Autorzy:: Valverde-Lopez JA; Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Li-Bao L; Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Sierra R; Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Santos E; Pluripotent Cell Technology Unit, Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain.
Giovinazzo G; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Pluripotent Cell Technology Unit, Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain.
Díaz-Díaz C; Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Torres M; Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2024 Mar 15; Vol. 20 (3), pp. e1011193. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Cell Competition*/genetics
Proto-Oncogene Proteins c-bcl-2*/genetics
Proto-Oncogene Proteins c-bcl-2*/metabolism
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Animals ; Apoptosis/genetics ; Apoptosis Regulatory Proteins/metabolism ; Tumor Suppressor Proteins/metabolism ; Mice

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Skocz do pozycji: 2.

Tytuł:: β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53.
Autorzy:: Bourmoum M; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Radulovich N; University Health Network, Ontario Cancer Institute/Princess Margaret Cancer Centre, Toronto, ON, Canada.
Sharma A; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Tkach JM; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Tsao MS; University Health Network, Ontario Cancer Institute/Princess Margaret Cancer Centre, Toronto, ON, Canada.
Pelletier L; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 07; Vol. 19 (2), pp. e0295030. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: beta Catenin*/genetics
beta Catenin*/metabolism
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Adenomatous Polyposis Coli Protein*/genetics
Adenomatous Polyposis Coli Protein*/metabolism
Animals ; Humans ; Centrosome/metabolism ; Pyrimidines ; Sulfones ; Wnt Signaling Pathway

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Skocz do pozycji: 3.

Tytuł:: AURKB promotes bladder cancer progression by deregulating the p53 DNA damage response pathway via MAD2L2.
Autorzy:: Li L; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Jiang P; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Hu W; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Zou F; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Li M; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Rao T; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Ruan Y; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Yu W; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Ning J; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. .
Cheng F; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Mar 21; Vol. 22 (1), pp. 295. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/metabolism
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/pathology
Animals ; Humans ; Mice ; Aurora Kinase B/genetics ; Aurora Kinase B/metabolism ; Cell Line, Tumor ; Cell Proliferation/genetics ; DNA Repair ; Gene Expression Regulation, Neoplastic ; Mad2 Proteins/genetics ; Mad2 Proteins/metabolism

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Skocz do pozycji: 4.

Tytuł:: Reconciling ASPP-p53 binding mode discrepancies through an ensemble binding framework that bridges crystallography and NMR data.
Autorzy:: Liu T; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Huang S; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Zhang Q; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Xia Y; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Zhang M; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Sun B; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2024 Feb 07; Vol. 20 (2), pp. e1011519. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis Regulatory Proteins*/chemistry
Tumor Suppressor Protein p53*/chemistry
Crystallography ; Protein Binding ; Apoptosis

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Skocz do pozycji: 5.

Tytuł:: Cyclin B2 impairs the p53 signaling in nasopharyngeal carcinoma.
Autorzy:: Liu Q; Department of Otolaryngology, Qingdao Municipal Hospital, NO. 1, Shibei District, Jiaozhou Road, 266011, Qingdao, Shandong, P.R. China.
Yuan Y; Department of Otolaryngology, Qingdao Municipal Hospital, NO. 1, Shibei District, Jiaozhou Road, 266011, Qingdao, Shandong, P.R. China.
Shang X; Department of Otolaryngology, Qingdao Municipal Hospital, NO. 1, Shibei District, Jiaozhou Road, 266011, Qingdao, Shandong, P.R. China.
Xin L; Department of Otolaryngology, Qingdao Municipal Hospital, NO. 1, Shibei District, Jiaozhou Road, 266011, Qingdao, Shandong, P.R. China. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2024 Jan 02; Vol. 24 (1), pp. 25. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclin B2*/genetics
Cyclin B2*/metabolism
Nasopharyngeal Carcinoma*/genetics
Nasopharyngeal Carcinoma*/pathology
Nasopharyngeal Neoplasms*/genetics
Nasopharyngeal Neoplasms*/pathology
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Humans ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Signal Transduction/genetics

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Skocz do pozycji: 6.

Tytuł:: The p53 protein is a suppressor of Atox1 copper chaperon in tumor cells under genotoxic effects.
Autorzy:: Tsymbal S; International Institute 'Solution Chemistry of Advanced Materials and Technologies', ITMO University, St. Petersburg, Russia.
Refeld A; International Institute 'Solution Chemistry of Advanced Materials and Technologies', ITMO University, St. Petersburg, Russia.
Zatsepin V; Kirov Military Medical Academy, St. Petersburg, Russia.
Kuchur O; International Institute 'Solution Chemistry of Advanced Materials and Technologies', ITMO University, St. Petersburg, Russia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Dec 21; Vol. 18 (12), pp. e0295944. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Copper*/metabolism
Copper Transport Proteins ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; DNA Damage

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Skocz do pozycji: 7.

Tytuł:: HABP 4 overexpression promotes apoptosis in goat turbinate bone cells.
Autorzy:: Wang X; College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Hua X; College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Zhang H; College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Ren Y; College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Yang F; College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Zhu J; Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province, Chengdu, China.; Pokaż więcej
Źródło:: Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (9), pp. 4187-4195. Date of Electronic Publication: 2022 May 06.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/metabolism
Tumor Suppressor Protein p53*/pharmacology
Goats*/genetics
Goats*/metabolism
Animals ; bcl-2-Associated X Protein/genetics ; Turbinates/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Apoptosis/genetics ; Cell Proliferation/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

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Skocz do pozycji: 8.

Tytuł:: Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy.
Autorzy:: Ma M; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Wei N; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Yang J; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Ding T; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Song A; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Chen L; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Zheng S; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.; Laboratory of Pharmacology of Chinese Medicine, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.
Jin H; Department of Pharmacology, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.; Laboratory of Pharmacology of Chinese Medicine, School of Pharmacy, Wannan Medical College, Wuhu, Anhui, P.R. China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 621-629.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Tumor Suppressor Protein p53*/pharmacology
Mice ; Animals ; Mice, Inbred ICR ; Liver Cirrhosis/pathology ; Cellular Senescence ; RNA, Small Interfering ; Transcription Factors/metabolism ; Nuclear Receptor Coactivators/genetics ; Nuclear Receptor Coactivators/metabolism

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Skocz do pozycji: 9.

Tytuł:: LRRC8A promotes Glaesserella parasuis cytolethal distending toxin-induced p53-dependent apoptosis in NPTr cells.
Autorzy:: Mao W; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Wang Z; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Wen S; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Lin Y; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Gu J; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Sun J; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Wang H; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Cao Q; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Xu Y; Institute of Animal Husbandry and Veterinary Research, Henan Academy of Agricultural Sciences, Zhengzhou, China.
Xu X; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Cai X; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.; Pokaż więcej
Źródło:: Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2287339. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Bacterial Toxins*/genetics
Swine ; Animals ; Apoptosis ; Carrier Proteins

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Skocz do pozycji: 10.

Tytuł:: p53 and p21 dynamics encode single-cell DNA damage levels, fine-tuning proliferation and shaping population heterogeneity.
Autorzy:: Gutu N; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; Humboldt-Universität zu Berlin, Berlin, Germany.
Binish N; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; Hertie Institute for Clinical Brain Research, Center for Neurology, University Medical Center Tübingen, Tübingen, Germany.
Keilholz U; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; German Cancer Consortium, Deutschen Konsortiums für Translationale Krebsforschung (DKTK), Berlin, Germany.
Herzel H; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany.; Humboldt-Universität zu Berlin, Berlin, Germany.; Institute for Theoretical Biology, Berlin, Germany.
Granada AE; Charité Universitätsmedizin, Charité Comprehensive Cancer Center, Berlin, Germany. .; German Cancer Consortium, Deutschen Konsortiums für Translationale Krebsforschung (DKTK), Berlin, Germany. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2023 Nov 24; Vol. 6 (1), pp. 1196. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
DNA Damage*
Humans ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Signal Transduction ; Cell Proliferation

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Skocz do pozycji: 11.

Tytuł:: Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties.
Autorzy:: Sakaguchi S; Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Nakagawa N; Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Wahba HM; Département de Biochimie et Médicine Moléculaire, Université de Montréal, C.P. 6128 Succursale Centre-Ville, Montréal, QC H3C 3J7, Canada.; Department of Biochemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 2722165, Egypt.
Wada J; Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Kamada R; Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Omichinski JG; Département de Biochimie et Médicine Moléculaire, Université de Montréal, C.P. 6128 Succursale Centre-Ville, Montréal, QC H3C 3J7, Canada.
Sakaguchi K; Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 22; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/metabolism
Animals ; Guinea Pigs ; Humans ; Opossums/metabolism ; Sheep ; Tupaia/metabolism

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Skocz do pozycji: 12.

Tytuł:: CKAP4 and mutant p53 cooperatively abrogate cell cycle checkpoint to induce genotoxic resistance in ovarian cancer.
Autorzy:: Huang C; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.; Gynecological Oncology Research and Engineering Center of Hunan Province, Changsha, China.
Zhao W; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.; Gynecological Oncology Research and Engineering Center of Hunan Province, Changsha, China.
Hao Q; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Chen J; Department of Neurosurgery, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai, China.
Wu L; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.; Gynecological Oncology Research and Engineering Center of Hunan Province, Changsha, China.
Yang W; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.; Gynecological Oncology Research and Engineering Center of Hunan Province, Changsha, China.
Lu H; Department of Biochemistry and Molecular Biology and Tulane Cancer Center, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Zhang Y; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.; Gynecological Oncology Research and Engineering Center of Hunan Province, Changsha, China.
Zhou X; Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.; Shanghai Key Laboratory of Medical Epigenetics, International Co-Laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1476.
Typ publikacji:: Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Ovarian Neoplasms*/genetics
Humans ; Female ; Cell Cycle Checkpoints ; DNA Damage/genetics ; Membrane Proteins/metabolism

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Skocz do pozycji: 13.

Tytuł:: EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression.
Autorzy:: Wang Z; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Chao Z; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang Q; Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zou F; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Song T; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Xu L; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Ning J; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. .
Cheng F; Department of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Jan 26; Vol. 22 (1), pp. 104. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/metabolism
Prostatic Neoplasms*/pathology
Humans ; Male ; Lipid Metabolism ; Lipids ; Exodeoxyribonucleases/metabolism ; DNA Repair Enzymes

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Skocz do pozycji: 14.

Tytuł:: A Missense Variant in TP53 Could Be a Genetic Biomarker Associated with Bone Tissue Alterations.
Autorzy:: Usategui-Martín R; Department of Cell Biology, Genetics, Histology and Pharmacology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.; IOBA-Eye Institute, University of Valladolid, 47011 Valladolid, Spain.
Galindo-Cabello N; Department of Cell Biology, Genetics, Histology and Pharmacology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.; IOBA-Eye Institute, University of Valladolid, 47011 Valladolid, Spain.
Pastor-Idoate S; IOBA-Eye Institute, University of Valladolid, 47011 Valladolid, Spain.
Fernández-Gómez JM; Department of Cell Biology, Genetics, Histology and Pharmacology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.
Del Real Á; Department of Medicine and Psychiatry, Faculty of Medicine, Valdecilla Research Institute (IDIVAL), University of Cantabria, 39011 Santander, Spain.
Ferreño D; Laboratory of the Materials Science and Engineering Division-LADICIM, Faculty of Civil Engineering, University of Cantabria, 39011 Santander, Spain.
Lapresa R; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, 37008 Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), University Hospital of Salamanca, University of Salamanca, CSIC, 37008 Salamanca, Spain.
Martín-Rodriguez F; Department of Medicine, Dermatology and Toxicology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.
Riancho JA; Department of Medicine and Psychiatry, Faculty of Medicine, Valdecilla Research Institute (IDIVAL), University of Cantabria, 39011 Santander, Spain.; Internal Medicine Department, Marqués de Valdecilla University Hospital, 39008 Santander, Spain.
Almeida Á; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, 37008 Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), University Hospital of Salamanca, University of Salamanca, CSIC, 37008 Salamanca, Spain.
Pérez-Castrillón JL; Department of Medicine, Dermatology and Toxicology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.; Internal Medicine Department, University Hospital Rio Hortega of Valladolid, 47012 Valladolid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:: Journal Article
MeSH Terms:: Bone Diseases, Metabolic*
Tumor Suppressor Protein p53*/genetics
Animals ; Mice ; Biomarkers ; Bone and Bones ; Case-Control Studies ; Genetic Predisposition to Disease ; Polymorphism, Single Nucleotide ; Humans

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Skocz do pozycji: 15.

Tytuł:: Identification of the prognostic immune subtype in copy-number high endometrial cancer.
Autorzy:: Mao M; Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Obstetric & Gynecologic Diseases, Beijing, China.
Jiang F; Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Obstetric & Gynecologic Diseases, Beijing, China. .
Han R; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xiang Y; Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Obstetric & Gynecologic Diseases, Beijing, China.; Pokaż więcej
Źródło:: Journal of gynecologic oncology [J Gynecol Oncol] 2024 Jan; Vol. 35 (1), pp. e8. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*/genetics
Endometrial Neoplasms*/genetics
Female ; Humans ; Prognosis ; Databases, Factual ; Biomarkers

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Skocz do pozycji: 16.

Tytuł:: Angiotensin II-induced vascular endothelial cells ferroptosis via P53-ALOX12 signal axis.
Autorzy:: Liu C; Department of Cardiology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.; National Clinical Research Center for Aging and Medicine, Jing an District Central Hospital, Shanghai, China.
Shen Y; Department of General Practice, Pudong New Area District Zhoupu Hospital, Shanghai, China.
Cavdar O; Department of Cardiology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Huang J; Department of Geriatrics, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Fang H; Department of Cardiology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.; Pokaż więcej
Źródło:: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2023 Dec 31; Vol. 45 (1), pp. 2180019.
Typ publikacji:: Journal Article
MeSH Terms:: Ferroptosis*
Tumor Suppressor Protein p53*
Human Umbilical Vein Endothelial Cells*
Arachidonate 12-Lipoxygenase*
Angiotensin II ; Endothelial Cells ; Iron ; Humans

Czasopismo naukowe

na półce

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Skocz do pozycji: 17.

Tytuł:: A Second Career for p53 as A Broad-Spectrum Antiviral?
Autorzy:: Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Dec 03; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 03.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*
Tumor Suppressor Protein p53*/metabolism
Virus Diseases*
Viruses*/genetics
Viruses*/metabolism
Humans ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Immunity, Innate ; SARS-CoV-2/metabolism ; Viral Proteins/genetics ; Viral Proteins/metabolism

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Skocz do pozycji: 18.

Tytuł:: Effects of blood components of preoperative autologous blood donation on functions of myelopoietic stem cells.
Autorzy:: Bai Y; Department of Anesthesiology and Perioperative Medicine, Gongli Hospital, Naval Military Medical University, Shanghai, People's Republic of China.
Su Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian, People's Republic of China.
Wang J; Department of Anesthesiology and Perioperative Medicine, Gongli Hospital, Naval Military Medical University, Shanghai, People's Republic of China.
Yao N; Department of Anesthesiology and Perioperative Medicine, Gongli Hospital, Naval Military Medical University, Shanghai, People's Republic of China.
Duan L; Department of Anesthesiology and Perioperative Medicine, Gongli Hospital, Naval Military Medical University, Shanghai, People's Republic of China.
Liu T; Department of Anesthesiology and Perioperative Medicine, Gongli Hospital, Naval Military Medical University, Shanghai, People's Republic of China.
Guo J; Department of Anesthesiology and Perioperative Medicine, Gongli Hospital, Naval Military Medical University, Shanghai, People's Republic of China.; Pokaż więcej
Źródło:: Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2240666.
Typ publikacji:: Journal Article
MeSH Terms:: Blood Donation*
Tumor Suppressor Protein p53*/metabolism
Male ; Humans ; Animals ; Rabbits ; Reactive Oxygen Species/metabolism ; Blood Transfusion, Autologous ; Hematopoietic Stem Cells/metabolism

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Skocz do pozycji: 19.

Tytuł:: Clinical outcomes and characteristics of patients with TP53 -mutated myelodysplastic syndromes.
Autorzy:: Zhang L; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Chen K; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Li Y; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Chen Q; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Shi W; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Ji T; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Tao H; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
He Z; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Wang C; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.
Yu L; Department of Hematology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, People's Republic of China.; Department of Hematology, The Huai'an Clinical College of Xuzhou Medical University, Huai'an, People's Republic of China.; Key Laboratory of Hematology of Nanjing Medical University, Nanjing, People's Republic of China.; Pokaż więcej
Źródło:: Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2181773.
Typ publikacji:: Journal Article
MeSH Terms:: Myelodysplastic Syndromes*/diagnosis
Myelodysplastic Syndromes*/drug therapy
Myelodysplastic Syndromes*/genetics
Tumor Suppressor Protein p53*/genetics
Humans ; Chromosome Aberrations ; Leukemia, Myeloid, Acute/genetics ; Mutation ; Prognosis ; Retrospective Studies ; Treatment Outcome

Czasopismo naukowe

na półce

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Skocz do pozycji: 20.

Tytuł:: Comprehensive Assessment of ERα, PR, Ki67, P53 to Predict the Risk of Lymph Node Metastasis in Low-Risk Endometrial Cancer.
Autorzy:: Huang Y; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jiang P; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Kong W; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tu Y; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li N; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wang J; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou Q; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuan R; Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Pokaż więcej
Źródło:: Journal of investigative surgery : the official journal of the Academy of Surgical Research [J Invest Surg] 2023 Dec; Vol. 36 (1), pp. 2152508.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Suppressor Protein p53*
Endometrial Neoplasms*/diagnosis
Endometrial Neoplasms*/surgery
Female ; Humans ; Lymphatic Metastasis/diagnosis ; Lymphatic Metastasis/pathology ; Ki-67 Antigen ; Estrogen Receptor alpha ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Lymph Node Excision ; Retrospective Studies

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