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Tytuł:
G protein coupled receptor kinase 5 modifies the nucleolar stress response activated by actinomycin D.
Autorzy:
Sok V; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Jacinto AZ; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Peng N; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Eldemerdash M; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Le L; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Tran PD; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Feng LF; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Patel JR; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Gi M; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
Ammon JC; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
So CH; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.; Roseman University of Health Sciences, School of Pharmacy, Henderson, NV 89014, USA.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Aug; Vol. 99 (4), pp. 508-518. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Antibiotics, Antineoplastic/*pharmacology
Cell Nucleolus/*pathology
Dactinomycin/*pharmacology
G-Protein-Coupled Receptor Kinase 5/*metabolism
Neoplasms/*pathology
Nuclear Proteins/*metabolism
Apoptosis ; Cell Nucleolus/drug effects ; Cell Nucleolus/genetics ; Cell Nucleolus/metabolism ; G-Protein-Coupled Receptor Kinase 5/genetics ; Humans ; Neoplasms/drug therapy ; Neoplasms/genetics ; Neoplasms/metabolism ; Nuclear Proteins/genetics ; Nucleophosmin ; Phosphorylation ; Protein Binding ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Endothelin-1, endothelin receptor antagonists, and vein graft occlusion in coronary artery bypass surgery: 20 years on and still no journey from bench to bedside.
Autorzy:
Dashwood MR; Surgical and Interventional Sciences, Royal Free Hospital Campus, University College Medical School, London, United Kingdom.
Loesch A; Centre for Rheumatology, Royal Free Hospital Campus, University College Medical School, London, United Kingdom.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Sep; Vol. 98 (9), pp. 570-578. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Coronary Artery Bypass/*adverse effects
Coronary Artery Disease/*surgery
Endothelin Receptor Antagonists/*therapeutic use
Endothelin-1/*metabolism
Graft Occlusion, Vascular/*etiology
Animals ; Cell Proliferation/drug effects ; Coronary Artery Bypass/methods ; Disease Models, Animal ; Drug Repositioning ; Endothelin Receptor Antagonists/pharmacology ; Endothelin-1/antagonists & inhibitors ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/immunology ; Endothelium, Vascular/pathology ; Endothelium, Vascular/surgery ; Graft Occlusion, Vascular/pathology ; Graft Occlusion, Vascular/prevention & control ; Graft Rejection ; Humans ; Saphenous Vein/drug effects ; Saphenous Vein/immunology ; Saphenous Vein/pathology ; Saphenous Vein/surgery ; Vascular Patency/drug effects
Czasopismo naukowe
Tytuł:
Mechanisms of NADPH - cytochrome P450 oxidoreductase induction by dexamethasone in the H4IIE rat hepatoma cell line.
Autorzy:
Riddick DS; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.
Mullen Grey AK; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 May; Vol. 98 (5), pp. 267-274. Date of Electronic Publication: 2019 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*pathology
Dexamethasone/*pharmacology
Liver Neoplasms/*pathology
NADPH-Ferrihemoprotein Reductase/*biosynthesis
Animals ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Enzyme Induction/drug effects ; NADPH-Ferrihemoprotein Reductase/genetics ; Pregnane X Receptor/metabolism ; RNA, Messenger/genetics ; Rats ; Receptors, Glucocorticoid/metabolism
Czasopismo naukowe
Tytuł:
A linear-amplification VDJ-seq technique for quantification of immunoglobulin and T cell receptor diversity.
Autorzy:
Zhao H; Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Li Z; Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Zhu Y; Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
Hao B; Guangdong Provincial Key Laboratory of Tumor Immunotherapy, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.; Henan Medical Genetics Institute, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan Province, P.R. China.
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Źródło:
Genome [Genome] 2020 Mar; Vol. 63 (3), pp. 145-153. Date of Electronic Publication: 2019 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Nucleotide Sequencing/*methods
Immunoglobulins/*genetics
Receptors, Antigen, T-Cell/*genetics
Animals ; CRISPR-Cas Systems ; Mice ; Sequence Analysis, DNA ; V(D)J Recombination
Czasopismo naukowe
Tytuł:
Molecular characterization of sugar taste receptors in the cotton bollworm Helicoverpa armigera.
Autorzy:
Xu W; a School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia.
Liu N; b Key Laboratory of Forest Disaster Warning and Control of Yunnan Province, Southwest Forestry University, Kunming 650224, China.
Liao Y; a School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia.
Anderson A; c CSIRO Ecosystem Sciences, Black Mountain, ACT 2601, Australia.
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Źródło:
Genome [Genome] 2017 Dec; Vol. 60 (12), pp. 1037-1044. Date of Electronic Publication: 2017 Aug 21.
Typ publikacji:
Journal Article
MeSH Terms:
Taste*
Insect Proteins/*genetics
Lepidoptera/*genetics
Receptors, Cell Surface/*genetics
Sugars/*metabolism
Animals ; Conserved Sequence ; Evolution, Molecular ; Female ; Insect Proteins/chemistry ; Insect Proteins/metabolism ; Lepidoptera/classification ; Male ; Ovary/metabolism ; Phylogeny ; Protein Domains ; Pseudogenes ; Receptors, Cell Surface/chemistry ; Receptors, Cell Surface/metabolism ; Testis/metabolism
Czasopismo naukowe
Tytuł:
Role of endothelin-1 and its receptors, ET A and ET B , in the survival of human vascular endothelial cells.
Autorzy:
Mikhail M; a Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Vachon PH; a Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
D'Orléans-Juste P; b Department of Pharmacology and Physiology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Jacques D; a Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Bkaily G; a Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2017 Oct; Vol. 95 (10), pp. 1298-1305. Date of Electronic Publication: 2017 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Endothelial Cells/*drug effects
Endothelin-1/*pharmacology
Receptor, Endothelin A/*agonists
Receptor, Endothelin B/*agonists
Caspase 3/metabolism ; Cell Survival/drug effects ; Cells, Cultured ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Endothelin A Receptor Antagonists/pharmacology ; Endothelin B Receptor Antagonists/pharmacology ; Genistein/toxicity ; Humans ; Receptor, Endothelin A/metabolism ; Receptor, Endothelin B/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Difference in the response to angiotensin II between left and right ventricular endocardial endothelial cells.
Autorzy:
Jacques D; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Abdel-Karim Abdel-Malak N; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Abou Abdallah N; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Al-Khoury J; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Bkaily G; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2017 Oct; Vol. 95 (10), pp. 1271-1282. Date of Electronic Publication: 2017 Jul 20.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Angiotensin II/*pharmacology
Endocardium/*drug effects
Endothelial Cells/*drug effects
Heart Ventricles/*drug effects
Calcium/metabolism ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Cells, Cultured ; Cytosol/metabolism ; Dose-Response Relationship, Drug ; Endocardium/metabolism ; Endothelial Cells/metabolism ; Heart Ventricles/metabolism ; Humans ; Receptor, Angiotensin, Type 1/agonists ; Receptor, Angiotensin, Type 1/metabolism ; Receptor, Angiotensin, Type 2/agonists ; Receptor, Angiotensin, Type 2/metabolism ; Time Factors
Czasopismo naukowe
Tytuł:
Angiotensin II receptors' modulation of calcium homeostasis in human vascular endothelial cells.
Autorzy:
Kamal M; Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Jacques D; Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Bkaily G; Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2017 Oct; Vol. 95 (10), pp. 1289-1297. Date of Electronic Publication: 2017 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium/*metabolism
Endothelial Cells/*metabolism
Receptor, Angiotensin, Type 1/*metabolism
Receptor, Angiotensin, Type 2/*metabolism
Active Transport, Cell Nucleus ; Adolescent ; Adult ; Angiotensin II/pharmacology ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Cell Nucleus/metabolism ; Cells, Cultured ; Cytosol/metabolism ; Dose-Response Relationship, Drug ; Endothelial Cells/drug effects ; Homeostasis ; Humans ; Middle Aged ; Protein Synthesis Inhibitors/pharmacology ; Receptor, Angiotensin, Type 1/drug effects ; Receptor, Angiotensin, Type 2/drug effects ; Young Adult
Czasopismo naukowe
Tytuł:
Entry, infection, replication, and egress of human polyomaviruses: an update.
Autorzy:
Bhattacharjee S; Cell and Molecular Biology Laboratory, Department of Zoology, University of North Bengal, Raja Rammohunpur, P.O. North Bengal University, Siliguri, District Darjeeling, West Bengal, PIN 734013, India.; Cell and Molecular Biology Laboratory, Department of Zoology, University of North Bengal, Raja Rammohunpur, P.O. North Bengal University, Siliguri, District Darjeeling, West Bengal, PIN 734013, India.
Chattaraj S; Cell and Molecular Biology Laboratory, Department of Zoology, University of North Bengal, Raja Rammohunpur, P.O. North Bengal University, Siliguri, District Darjeeling, West Bengal, PIN 734013, India.; Cell and Molecular Biology Laboratory, Department of Zoology, University of North Bengal, Raja Rammohunpur, P.O. North Bengal University, Siliguri, District Darjeeling, West Bengal, PIN 734013, India.
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Źródło:
Canadian journal of microbiology [Can J Microbiol] 2017 Mar; Vol. 63 (3), pp. 193-211. Date of Electronic Publication: 2016 Oct 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Virus Internalization*
Virus Replication*
Virus Shedding*
Polyomavirus/*physiology
Animals ; Cell Nucleus ; Genome, Viral ; Humans
Czasopismo naukowe
Tytuł:
Fluoxetine reverses the behavioral despair induced by neurogenic stress in mice: role of N-methyl-d-aspartate and opioid receptors.
Autorzy:
Haj-Mirzaian A; a Experimental Medicine Research Center, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.; b Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.
Kordjazy N; a Experimental Medicine Research Center, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.; b Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.
Ostadhadi S; b Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.; c Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Amiri S; a Experimental Medicine Research Center, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.; b Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.
Haj-Mirzaian A; a Experimental Medicine Research Center, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.; b Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.
Dehpour A; a Experimental Medicine Research Center, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.; b Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2016 Jun; Vol. 94 (6), pp. 599-612. Date of Electronic Publication: 2016 Jan 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antidepressive Agents, Second-Generation/*therapeutic use
Depression/*drug therapy
Fluoxetine/*therapeutic use
Receptors, N-Methyl-D-Aspartate/*physiology
Receptors, Opioid/*physiology
Stress, Psychological/*drug therapy
Animals ; Depression/etiology ; Depression/psychology ; Dizocilpine Maleate/pharmacology ; Male ; Mice ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Stress, Psychological/complications ; Stress, Psychological/psychology
Czasopismo naukowe
Tytuł:
Role of phospholipase C in catecholamine-induced increase in myocardial protein synthesis.
Autorzy:
Tappia PS; Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, R2H 2A6 MB Canada.
Ramjiawan B; Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, R2H 2A6 MB Canada.; Department of Pharmacology and Therapeutics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, R3E 0T6 MB, Canada.
Dhalla NS; Institute of Cardiovascular Sciences, Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, R3E 0J9 MB, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Oct 01; Vol. 100 (10), pp. 945-955. Date of Electronic Publication: 2022 Jun 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Isoenzymes*/metabolism
Type C Phospholipases*/metabolism
Adenylyl Cyclases/metabolism ; Cardiomegaly/chemically induced ; Catecholamines/adverse effects ; GTP-Binding Proteins/adverse effects ; GTP-Binding Proteins/metabolism ; Humans ; Inositol/adverse effects ; Norepinephrine/pharmacology ; Phosphatidylinositols ; Receptors, Adrenergic/metabolism
Czasopismo naukowe
Tytuł:
The protective effect of muscimol against systemic inflammatory response in endotoxemic mice is independent of GABAergic and cholinergic receptors.
Autorzy:
Li YH; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 70428, Taiwan.
Hsu DZ; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 70428, Taiwan.
Liu CT; Research Center for Traditional Chinese Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Chandrasekaran VRM; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 70428, Taiwan.
Liu MY; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 70428, Taiwan.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Jul 01; Vol. 100 (7), pp. 665-678. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Endotoxemia*/chemically induced
Endotoxemia*/drug therapy
Sepsis*
Animals ; Interleukin-10/metabolism ; Interleukin-12/metabolism ; Lipopolysaccharides/pharmacology ; Mice ; Muscimol/pharmacology ; Muscimol/therapeutic use ; NF-kappa B/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Receptors, Cholinergic/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Intrathecal baclofen, a GABAB receptor agonist, inhibits the expression of p-CREB and NR2B in the spinal dorsal horn in rats with diabetic neuropathic pain.
Autorzy:
Liu P; a Department of Anesthesiology, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang 050051, Hebei Province, China.
Guo WY
Zhao XN
Bai HP
Wang Q
Wang XL
Zhang YZ
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2014 Aug; Vol. 92 (8), pp. 655-60. Date of Electronic Publication: 2014 Jul 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Baclofen/*pharmacology
CREB-Binding Protein/*metabolism
Diabetic Neuropathies/*metabolism
GABA-B Receptor Agonists/*pharmacology
Neuralgia/*drug therapy
Receptors, N-Methyl-D-Aspartate/*metabolism
Spinal Cord Dorsal Horn/*drug effects
Animals ; Baclofen/therapeutic use ; CREB-Binding Protein/genetics ; Diabetic Neuropathies/physiopathology ; GABA-B Receptor Agonists/therapeutic use ; GABA-B Receptor Antagonists/pharmacology ; Gene Expression ; Injections, Spinal ; Male ; Neuralgia/metabolism ; Neuralgia/physiopathology ; Pain Measurement ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/genetics ; Spinal Cord Dorsal Horn/metabolism
Czasopismo naukowe
Tytuł:
On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions.
Autorzy:
Phạm TTT; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Rainey JK; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.; Department of Chemistry and School of Biomedical Engineering, Dalhousie University, Halifax, NS B3H 4R2, Canada.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Dec; Vol. 99 (6), pp. 683-692. Date of Electronic Publication: 2021 May 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Receptors, G-Protein-Coupled*/metabolism
Ligands ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Nuclear Magnetic Resonance, Biomolecular ; Protein Binding
Czasopismo naukowe
Tytuł:
Saikosaponin-d protects against liver fibrosis by regulating the estrogen receptor-β/NLRP3 inflammasome pathway.
Autorzy:
Lin L; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhou M; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Que R; Department of Gastroenterology, Shanghai TCM Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chen Y; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Liu X; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhang K; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shi Z; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li Y; Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Oct; Vol. 99 (5), pp. 666-674. Date of Electronic Publication: 2021 May 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Estrogen Receptor beta/*antagonists & inhibitors
Inflammasomes/*drug effects
Liver Cirrhosis/*drug therapy
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Oleanolic Acid/*analogs & derivatives
Protective Agents/*pharmacology
Saponins/*pharmacology
Animals ; Carbon Tetrachloride ; Cells, Cultured ; Estrogen Receptor beta/metabolism ; Inflammasomes/metabolism ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Oleanolic Acid/pharmacology
Czasopismo naukowe
Tytuł:
S -allylcysteine inhibits chondrocyte inflammation to reduce human osteoarthritis via targeting RAGE, TLR4, JNK, and Nrf2 signaling: comparison with colchicine.
Autorzy:
Elmazoglu Z; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey.
Aydın Bek Z; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey.
Sarıbaş SG; Department of Histology and Embryology, Faculty of Medicine, Kırsehir Ahi Evran University, Bağbaşı Campus, Kırşehir, Turkey.
Özoğul C; Department of Histology and Embryology, Faculty of Medicine, Kyrenia University, Kyrenia, Cyprus.
Goker B; Department of Rheumatology, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey.
Bitik B; Ankara Research and Education Hospital, Altındağ, Ankara, Turkey.
Aktekin CN; Department of Orthopedics and Traumatology, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey.
Karasu Ç; Department of Medical Pharmacology, Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Gazi University, Beşevler, Ankara, Turkey.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Oct; Vol. 99 (5), pp. 645-654. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chondrocytes/*drug effects
Cysteine/*analogs & derivatives
Inflammation/*drug therapy
Osteoarthritis/*drug therapy
Aged ; Antigens, Neoplasm/metabolism ; Chondrocytes/metabolism ; Cysteine/pharmacology ; Female ; Humans ; Inflammation/metabolism ; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors ; JNK Mitogen-Activated Protein Kinases/metabolism ; Male ; Middle Aged ; Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Mitogen-Activated Protein Kinases/metabolism ; NF-E2-Related Factor 2/antagonists & inhibitors ; NF-E2-Related Factor 2/metabolism ; Osteoarthritis/metabolism ; Signal Transduction/drug effects ; Toll-Like Receptor 4/antagonists & inhibitors ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł:
The N -glycans of lactoferrin: more than just a sweet decoration.
Autorzy:
Zlatina K; Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.; Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Galuska SP; Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.; Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
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Źródło:
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Feb; Vol. 99 (1), pp. 117-127. Date of Electronic Publication: 2020 May 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Lactoferrin/*metabolism
Polysaccharides/*metabolism
Animals ; Cattle ; Endoplasmic Reticulum/metabolism ; Glycosylation ; Golgi Apparatus/metabolism ; Humans ; Lactoferrin/chemistry ; Polysaccharides/chemistry ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł:
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala.
Autorzy:
Razavi Y; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Karimi S; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Karimi-Haghighi S; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hesam S; Department of Neuroscience, Golestan University of Medical Sciences, Gorgan, Iran.
Haghparast A; Neuroscience Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Nov; Vol. 98 (11), pp. 741-752. Date of Electronic Publication: 2020 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Conditioning, Psychological/*physiology
Mifepristone/*administration & dosage
Morphine/*adverse effects
Opioid-Related Disorders/*drug therapy
Receptors, Glucocorticoid/*antagonists & inhibitors
Animals ; Basolateral Nuclear Complex/drug effects ; Basolateral Nuclear Complex/physiopathology ; Corticosterone/administration & dosage ; Cyclic AMP Response Element-Binding Protein/metabolism ; Disease Models, Animal ; Humans ; Male ; Nerve Net/drug effects ; Nerve Net/physiology ; Nucleus Accumbens/drug effects ; Nucleus Accumbens/physiology ; Opioid-Related Disorders/psychology ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/physiology ; Proto-Oncogene Proteins c-fos/metabolism ; Rats ; Receptors, Glucocorticoid/metabolism ; Reward ; Signal Transduction/drug effects ; Stereotaxic Techniques ; Stress, Psychological/chemically induced ; Stress, Psychological/physiopathology ; Stress, Psychological/psychology
Czasopismo naukowe
Tytuł:
Endokinin A/B stimulates rat gastric motility through myogenic NK1 receptors located in the fundus.
Autorzy:
Zhang J; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.
Ma C; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.
Wang R; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.
He C; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.
Li H; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.
Dong S; Institute of Biochemistry and Molecular Biology, School of Life Sciences, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.; Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, 222 Tianshui South Road, Lanzhou 730000, People's Republic of China.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Oct; Vol. 98 (10), pp. 691-699. Date of Electronic Publication: 2020 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Gastric Emptying/*drug effects
Gastric Fundus/*drug effects
Muscle Contraction/*drug effects
Muscle, Smooth/*drug effects
Peptide Fragments/*pharmacology
Receptors, Neurokinin-1/*agonists
Tachykinins/*pharmacology
Animals ; Gastric Fundus/metabolism ; In Vitro Techniques ; Male ; Muscle, Smooth/metabolism ; Pressure ; Rats, Wistar ; Receptors, Neurokinin-1/genetics ; Receptors, Neurokinin-1/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol trisphosphate-mediated intracellular calcium homeostasis.
Autorzy:
Balasubramanian V; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology-Madras, Chennai 600036, India.; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology-Madras, Chennai 600036, India.
Srinivasan B; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology-Madras, Chennai 600036, India.; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology-Madras, Chennai 600036, India.
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Źródło:
Genome [Genome] 2020 Feb; Vol. 63 (2), pp. 61-90. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium/*metabolism
Calcium-Binding Proteins/*physiology
Drosophila Proteins/*physiology
Inositol 1,4,5-Trisphosphate Receptors/*genetics
Nucleobindins/*physiology
Alleles ; Amino Acid Motifs ; Animals ; Calcium-Binding Proteins/chemistry ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Drosophila Proteins/chemistry ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/genetics ; Drosophila melanogaster/growth & development ; Drosophila melanogaster/metabolism ; GTP-Binding Protein alpha Subunits/metabolism ; Genes, Lethal ; Genetic Pleiotropy ; Golgi Apparatus/metabolism ; Homeostasis ; Humans ; Inositol 1,4,5-Trisphosphate/metabolism ; Mutation ; Nucleobindins/chemistry ; Nucleobindins/genetics ; Nucleobindins/metabolism ; Protein Domains ; Structural Homology, Protein
Czasopismo naukowe

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