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Wyszukujesz frazę ""reactive oxygen species"" wg kryterium: Temat


Tytuł :
Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production.
Autorzy :
Tang H; School of Pharmacy, Fudan University, Shanghai, 201203, China.
Liang Y; School of Pharmacy, Fudan University, Shanghai, 201203, China; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China.
Cheng J; School of Pharmacy, Fudan University, Shanghai, 201203, China.
Ding K; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. Electronic address: .
Wang Y; School of Pharmacy, Fudan University, Shanghai, 201203, China; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113531. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Azetidines/*pharmacology
Organoselenium Compounds/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
Tubulin/*metabolism
Tubulin Modulators/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Azetidines/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Organoselenium Compounds/chemical synthesis ; Organoselenium Compounds/chemistry ; Polymerization/drug effects ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Tubulin Modulators/chemical synthesis ; Tubulin Modulators/chemistry
Czasopismo naukowe
Tytuł :
Scavenging reactive oxygen species is a potential strategy to protect Larimichthys crocea against environmental hypoxia by mitigating oxidative stress.
Autorzy :
Luo SY; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Liu C; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Ding J; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Gao XM; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Wang JQ; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Zhang YB; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Du C; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Hou CC; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Zhu JQ; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China. E-mail:.
Lou B; Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang 310021, China. E-mail:.
Wu XF; State Key Laboratory of Large Yellow Croaker Breeding, Ningbo Academy of Oceanology and Fishery, Ningbo, Zhejiang 315012, China.
Shen WL; State Key Laboratory of Large Yellow Croaker Breeding, Ningbo Academy of Oceanology and Fishery, Ningbo, Zhejiang 315012, China.
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Źródło :
Zoological research [Zool Res] 2021 Sep 18; Vol. 42 (5), pp. 592-605.
Typ publikacji :
Journal Article
MeSH Terms :
Reactive Oxygen Species*
Antioxidants/*metabolism
Fishes/*metabolism
Oxidative Stress/*physiology
Oxygen/*chemistry
Oxygen/*metabolism
Animals ; Cell Line ; Cell Survival ; Environment ; Homeostasis ; NADP
Czasopismo naukowe
Tytuł :
Gene interfered-ferroptosis therapy for cancers.
Autorzy :
Gao J; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Luo T; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Wang J; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 07; Vol. 12 (1), pp. 5311. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Interference*
Cation Transport Proteins/*antagonists & inhibitors
Ferroptosis/*genetics
Iron/*metabolism
Lipocalin-2/*antagonists & inhibitors
Neoplasms/*therapy
Reactive Oxygen Species/*agonists
Animals ; CRISPR-Associated Proteins/genetics ; CRISPR-Associated Proteins/metabolism ; Cation Transport Proteins/genetics ; Cation Transport Proteins/metabolism ; Cell Line, Tumor ; Dependovirus/genetics ; Dependovirus/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Lipocalin-2/genetics ; Lipocalin-2/metabolism ; Liver/metabolism ; Liver/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; MicroRNAs/genetics ; MicroRNAs/metabolism ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Neoplasms/genetics ; Neoplasms/mortality ; Neoplasms/pathology ; Promoter Regions, Genetic ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Spleen/metabolism ; Spleen/pathology ; Survival Analysis ; Tumor Burden ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species.
Autorzy :
Pereira Barbosa-Carvalho AP; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
Texeira Costa Leitão DDS; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
Campos de Siqueira F; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
Zerlotti Mercadante A; Department of Food Science and Nutrition, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
Campos Chisté R; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.; Faculty of Food Engineering, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
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Źródło :
Journal of food science [J Food Sci] 2021 Sep; Vol. 86 (9), pp. 4045-4059. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Anacardiaceae*/chemistry
Fruit*/chemistry
Reactive Nitrogen Species*/chemistry
Reactive Oxygen Species*/chemistry
Antioxidants/chemistry ; Brazil ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł :
Tumor progress intercept by intervening in Caveolin-1 related intercellular communication via ROS-sensitive c-Myc targeting therapy.
Autorzy :
Zhou X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Liu X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Yang X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Wang L; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Hong Y; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Lian K; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Qiu G; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Shang X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Ma Z; Ocean College, Zhejiang University, Zhoushan, 316021, China.
Yuan H; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Hu F; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2021 Aug; Vol. 275, pp. 120958. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caveolin 1*
Exosomes*
Reactive Oxygen Species*
Neoplasms, Experimental/*drug therapy
Animals ; Cell Line, Tumor ; Drug Carriers ; Drug Liberation ; Female ; Mice ; Mice, Inbred BALB C ; Proto-Oncogene Proteins c-myc ; RAW 264.7 Cells ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Helicobacter pylori induced reactive oxygen Species: A new and developing platform for detection.
Autorzy :
Jain U; Amity Institute of Nanotechnology (AINT), Amity University Uttar Pradesh, Noida, India.
Saxena K; Amity Institute of Nanotechnology (AINT), Amity University Uttar Pradesh, Noida, India.
Chauhan N; Amity Institute of Nanotechnology (AINT), Amity University Uttar Pradesh, Noida, India.
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Źródło :
Helicobacter [Helicobacter] 2021 Jun; Vol. 26 (3), pp. e12796. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Helicobacter Infections*/diagnosis
Helicobacter Infections*/metabolism
Oxidative Stress*
Reactive Oxygen Species*/analysis
Reactive Oxygen Species*/metabolism
Gastric Mucosa/metabolism ; Gastric Mucosa/microbiology ; Helicobacter pylori ; Humans ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/microbiology
Czasopismo naukowe
Tytuł :
Electrochemical Measurements Reveal Reactive Oxygen Species in Stress Granules*.
Autorzy :
Hu K; Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.
Relton E; Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Locker N; Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Phan NTN; Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.
Ewing AG; Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Jul 05; Vol. 60 (28), pp. 15302-15306. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electrochemical Techniques*
Neoplasms/*diagnosis
Reactive Oxygen Species/*analysis
Humans ; Neoplasms/metabolism ; Neurodegenerative Diseases/diagnosis ; Neurodegenerative Diseases/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Virus Diseases/diagnosis ; Virus Diseases/metabolism
Czasopismo naukowe
Tytuł :
Effects of Superoxide Dismutase Inhibitors and Glucose on Cell Death and Generation of Reactive Oxygen Species in Pea Leaves.
Autorzy :
Samuilov VD; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. .
Kiselevsky DB; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. .
Dzyubinskaya EV; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Frolova OY; Institute of Mitoengineering, Lomonosov Moscow State University, Moscow, 119234, Russia.
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Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2021 Jul; Vol. 86 (7), pp. 878-886.
Typ publikacji :
Journal Article
MeSH Terms :
Reactive Oxygen Species*
Ditiocarb/*pharmacology
Glucose/*metabolism
Peas/*drug effects
Plant Epidermis/*drug effects
Superoxide Dismutase/*antagonists & inhibitors
Trientine/*pharmacology
Cell Death ; Chelating Agents/pharmacology ; Enzyme Inhibitors/pharmacology ; Glucose/pharmacology ; Peas/enzymology ; Peas/metabolism ; Peas/physiology ; Plant Epidermis/enzymology ; Plant Epidermis/metabolism ; Plant Epidermis/physiology ; Plant Leaves/drug effects ; Plant Leaves/enzymology ; Plant Leaves/metabolism ; Plant Leaves/physiology
Czasopismo naukowe
Tytuł :
Free Radicals and ROS Induce Protein Denaturation by UV Photostability Assay.
Autorzy :
Ruzza P; Padova Unit, Institute of Biomolecular Chemistry of CNR (ICB-CNR), Via F. Marzolo, 1, 35030 Padova, Italy.
Honisch C; Padova Unit, Institute of Biomolecular Chemistry of CNR (ICB-CNR), Via F. Marzolo, 1, 35030 Padova, Italy.; Department of Chemical Sciences, University of Padua, Via F. Marzolo, 1, 35030 Padova, Italy.
Hussain R; Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.
Siligardi G; Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 17; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Denaturation*/drug effects
Protein Denaturation*/radiation effects
Ultraviolet Rays*
Free Radicals/*chemistry
Proteins/*chemistry
Reactive Oxygen Species/*chemistry
Circular Dichroism ; Heating ; Reactive Oxygen Species/metabolism ; Spectrum Analysis ; Water/chemistry
Czasopismo naukowe
Tytuł :
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Autorzy :
Xi X; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Zhao Y; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Liu H; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Li Z; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Chen S; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Liu D; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Jun 15; Vol. 403 (2), pp. 112598. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
NF-E2-Related Factor 2/*genetics
Osteoblasts/*metabolism
Reactive Oxygen Species/*metabolism
Stem Cells/*metabolism
Adolescent ; Animals ; Cell Differentiation ; Cell Survival/drug effects ; Child ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Female ; Gene Expression Regulation ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Humans ; Hydroquinones/pharmacology ; Male ; Mechanotransduction, Cellular ; NAD(P)H Dehydrogenase (Quinone)/genetics ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; NF-E2-Related Factor 2/antagonists & inhibitors ; NF-E2-Related Factor 2/metabolism ; Osteoblasts/cytology ; Osteoblasts/drug effects ; Osteogenesis/genetics ; Osteopontin/genetics ; Osteopontin/metabolism ; Periodontal Ligament/cytology ; Periodontal Ligament/drug effects ; Periodontal Ligament/metabolism ; Primary Cell Culture ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Rats ; Rats, Wistar ; Reactive Oxygen Species/antagonists & inhibitors ; Stem Cells/cytology ; Stem Cells/drug effects ; Stress, Mechanical ; Tooth Movement Techniques/methods
Czasopismo naukowe
Tytuł :
Non-cytotoxic dosage of fumonisin B1 aggravates ochratoxin A-induced nephrocytotoxicity and apoptosis via ROS-dependent JNK/MAPK signaling pathway.
Autorzy :
Li H; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Wang M; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Kang W; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Lin Z; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Gan F; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Huang K; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2021 Jun 15; Vol. 457, pp. 152802. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Reactive Oxygen Species*/metabolism
Apoptosis/*drug effects
Fumonisins/*toxicity
Kidney/*drug effects
MAP Kinase Signaling System/*drug effects
Ochratoxins/*toxicity
Animals ; Apoptosis/physiology ; Cell Line ; Fumonisins/administration & dosage ; Kidney/metabolism ; Kidney/pathology ; Ochratoxins/administration & dosage ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Swine
Czasopismo naukowe
Tytuł :
Piperlongumine Analogs Promote A549 Cell Apoptosis through Enhancing ROS Generation.
Autorzy :
Sun AL; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.
Mu WW; School of Pharmaceutical Sciences, Liaocheng University, Liaocheng 252059, China.
Li YM; Shandong Center for Disease Control and Prevention, Jinan 250014, China.
Sun YL; Qingdao Vland Biotech INC, Qingdao 266000, China.
Li PX; School of Pharmaceutical Sciences, Liaocheng University, Liaocheng 252059, China.
Liu RM; School of Pharmaceutical Sciences, Liaocheng University, Liaocheng 252059, China.
Yang J; School of Pharmaceutical Sciences, Liaocheng University, Liaocheng 252059, China.
Liu GY; School of Pharmaceutical Sciences, Liaocheng University, Liaocheng 252059, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 28; Vol. 26 (11). Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Reactive Oxygen Species*
Dioxolanes/*chemistry
A549 Cells ; Antineoplastic Agents/pharmacology ; Cell Cycle ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation ; Chlorine/chemistry ; Electrons ; Humans ; Lipid Peroxidation ; Membrane Potential, Mitochondrial ; Oxidation-Reduction ; Tetrazolium Salts/chemistry ; Thiazoles/chemistry ; Thioredoxin-Disulfide Reductase/metabolism
Czasopismo naukowe
Tytuł :
Spectrophotometric assays for evaluation of Reactive Oxygen Species (ROS) in serum: general concepts and applications in dogs and humans.
Autorzy :
Rubio CP; Interdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Veterinary School, Campus of Excellence Mare Nostrum, University of Murcia, Campus de Espinardo s/n, 30100, Murcia, Spain.
Cerón JJ; Interdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Veterinary School, Campus of Excellence Mare Nostrum, University of Murcia, Campus de Espinardo s/n, 30100, Murcia, Spain. .
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Źródło :
BMC veterinary research [BMC Vet Res] 2021 Jun 26; Vol. 17 (1), pp. 226. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Reactive Oxygen Species/*blood
Spectrophotometry/*veterinary
Animals ; Dogs ; Humans ; Reactive Oxygen Species/chemistry ; Spectrophotometry/methods
Czasopismo naukowe
Tytuł :
In Situ Imaging of Cellular Reactive Oxygen Species and Caspase-3 Activity Using a Multifunctional Theranostic Probe for Cancer Diagnosis and Therapy.
Autorzy :
Wang K; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Zhang F; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Wei Y; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Wei W; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
Jiang L; Collaborative Innovation Center of Tumor Marker Detection Technology, Equipment and Diagnosis-Therapy Integration in Universities of Shandong, Shandong Province Key Laboratory of Detection Technology for Tumor Makers, School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China.
Liu Z; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.
Liu S; State Key Laboratory of Bioelectronics, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Jun 08; Vol. 93 (22), pp. 7870-7878. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3*
Metal Nanoparticles*
Neoplasms*/diagnostic imaging
Neoplasms*/drug therapy
Photochemotherapy*
Reactive Oxygen Species*
Apoptosis ; Cell Line, Tumor ; Hep G2 Cells ; Humans ; Precision Medicine ; Silver ; Theranostic Nanomedicine
Czasopismo naukowe
Tytuł :
The nephroprotective effects and mechanisms of rehmapicrogenin include ROS inhibition via an oestrogen-like pathway both in vivo and in vitro.
Autorzy :
Wang M; Henan University of Chinese Medicine, Zhengzhou 450046, China.
Ke Y; Henan University of Chinese Medicine, Zhengzhou 450046, China.
Li Y; Henan University of Chinese Medicine, Zhengzhou 450046, China.
Shan Z; Henan University of Chinese Medicine, Zhengzhou 450046, China.
Mi W; Henan University of Chinese Medicine, Zhengzhou 450046, China.
Cao Y; Henan University of Chinese Medicine, Zhengzhou 450046, China.
Feng W; Henan University of Chinese Medicine, Zhengzhou 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. Electronic address: .
Zheng X; Henan University of Chinese Medicine, Zhengzhou 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jun; Vol. 138, pp. 111305. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Estrogens*/metabolism
Acute Kidney Injury/*prevention & control
Drugs, Chinese Herbal/*therapeutic use
Estrogen Antagonists/*therapeutic use
Reactive Oxygen Species/*antagonists & inhibitors
Signal Transduction/*drug effects
Acute Kidney Injury/metabolism ; Acute Kidney Injury/pathology ; Animals ; Cell Line ; Cytoprotection/drug effects ; Cytoprotection/physiology ; Drugs, Chinese Herbal/pharmacology ; Estrogen Antagonists/pharmacology ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Rats ; Reactive Oxygen Species/metabolism ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Small-Molecule Inhibitors of Reactive Oxygen Species Production.
Autorzy :
Sassetti E; Center for Nanomedicine and Theranostics, Department of Chemistry, Technical University of Denmark, Kemitorvet 207, 2800 Kgs. Lyngby, Denmark.
Clausen MH; Center for Nanomedicine and Theranostics, Department of Chemistry, Technical University of Denmark, Kemitorvet 207, 2800 Kgs. Lyngby, Denmark.
Laraia L; Center for Nanomedicine and Theranostics, Department of Chemistry, Technical University of Denmark, Kemitorvet 207, 2800 Kgs. Lyngby, Denmark.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 May 13; Vol. 64 (9), pp. 5252-5275. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Reactive Oxygen Species/*metabolism
Small Molecule Libraries/*chemistry
Animals ; Ferroptosis/drug effects ; Free Radical Scavengers/chemistry ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Monoamine Oxidase/chemistry ; Monoamine Oxidase/metabolism ; NADPH Oxidases/antagonists & inhibitors ; NADPH Oxidases/metabolism ; Reactive Oxygen Species/chemistry ; Small Molecule Libraries/pharmacology ; Xanthine Dehydrogenase/chemistry ; Xanthine Dehydrogenase/metabolism
Czasopismo naukowe
Tytuł :
Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line.
Autorzy :
Coricovac D; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Dehelean CA; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Pinzaru I; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Mioc A; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Aburel OM; Faculty of Medicine 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Center for Translational Research and Systems Medicine, Faculty of Medicine,' Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Sq. no. 2, RO-300041 Timișoara, Romania.
Macasoi I; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Draghici GA; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Petean C; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Soica C; Faculty of Pharmacy, 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Research Center for Pharmaco-toxicological Evaluations, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Boruga M; Faculty of Medicine 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Vlaicu B; Faculty of Medicine 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.
Muntean MD; Faculty of Medicine 'Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, RO-300041 Timișoara, Romania.; Center for Translational Research and Systems Medicine, Faculty of Medicine,' Victor Babeș' University of Medicine and Pharmacy Timișoara, Eftimie Murgu Sq. no. 2, RO-300041 Timișoara, Romania.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 04; Vol. 22 (9). Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Melanocytes/*drug effects
Mitochondria/*drug effects
Pentacyclic Triterpenes/*pharmacology
Reactive Oxygen Species/*metabolism
Apoptosis/genetics ; Cell Line, Tumor ; Gene Expression Regulation ; Glycolysis/drug effects ; Glycolysis/genetics ; Humans ; Inhibitory Concentration 50 ; Melanocytes/metabolism ; Melanocytes/pathology ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/genetics ; Mitochondria/metabolism ; Oxidative Phosphorylation/drug effects ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/agonists ; Signal Transduction ; bcl-2 Homologous Antagonist-Killer Protein/genetics ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; bcl-Associated Death Protein/genetics ; bcl-Associated Death Protein/metabolism
Czasopismo naukowe
Tytuł :
Effects of Different Bone Substitutes on Reactive Oxygen Species Release in Leukocytes in Vitro: A Pilot Study.
Autorzy :
Nomeika D
Jasiunas A
Janužis G
Skrodenienė E
Banienė R
Juodžbalys G
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Źródło :
The International journal of oral & maxillofacial implants [Int J Oral Maxillofac Implants] 2021 May-Jun; Vol. 36 (3), pp. e42-e50.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Substitutes*
Leukocytes*
Reactive Oxygen Species*
Cross-Over Studies ; Humans ; Pilot Projects ; Prospective Studies ; Random Allocation
Czasopismo naukowe
Tytuł :
Knockdown of dual oxidase 1 suppresses activin A-induced fibrosis in cardiomyocytes via the reactive oxygen species-dependent pyroptotic pathway.
Autorzy :
Li S; Department of Cardiology, The First Affiliated Hospital of NanChang University, NanChang, Jiangxi Province, 330006, China; Department of Respiratory Medicine, The 908th Hospital of Chinese People's Liberation Army Joint Logistic Support Force, NanChang, Jiangxi Province, 330026, China.
Li Z; Department of Cardiology, The First Affiliated Hospital of NanChang University, NanChang, Jiangxi Province, 330006, China.
Yin R; Department of Cardiology, The First Affiliated Hospital of NanChang University, NanChang, Jiangxi Province, 330006, China.
Nie J; Department of Cardiology, The First Affiliated Hospital of NanChang University, NanChang, Jiangxi Province, 330006, China.
Fu Y; Department of Cardiology, The First Affiliated Hospital of NanChang University, NanChang, Jiangxi Province, 330006, China.
Ying R; Department of Cardiology, The First Affiliated Hospital of NanChang University, NanChang, Jiangxi Province, 330006, China. Electronic address: .
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Źródło :
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2021 Feb; Vol. 131, pp. 105902. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Activins/*pharmacology
Dual Oxidases/*genetics
Myocytes, Cardiac/*drug effects
Pyroptosis/*drug effects
Reactive Oxygen Species/*metabolism
Acetylcysteine/pharmacology ; Activins/antagonists & inhibitors ; Caspase 1/genetics ; Caspase 1/metabolism ; Coenzyme A Ligases/genetics ; Coenzyme A Ligases/metabolism ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Collagen Type III/genetics ; Collagen Type III/metabolism ; Dual Oxidases/antagonists & inhibitors ; Dual Oxidases/metabolism ; Free Radical Scavengers/pharmacology ; Gene Expression Regulation ; Humans ; Interleukin-18/genetics ; Interleukin-18/metabolism ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Oxidative Stress/drug effects ; Primary Cell Culture ; Pyroptosis/genetics ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Reactive Oxygen Species/agonists ; Reactive Oxygen Species/antagonists & inhibitors ; Signal Transduction ; Smad2 Protein/genetics ; Smad2 Protein/metabolism ; Smad3 Protein/genetics ; Smad3 Protein/metabolism
Czasopismo naukowe
Tytuł :
A biocompatible and pH-responsive nanohydrogel based on cellulose nanocrystal for enhanced toxic reactive oxygen species generation.
Autorzy :
You C; Jiangsu Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Co-Innovation Centre for Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China.
Ning L; Jiangsu Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Co-Innovation Centre for Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China.
Wu H; Jiangsu Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Co-Innovation Centre for Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China.
Huang C; Jiangsu Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Co-Innovation Centre for Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China. Electronic address: .
Wang F; Jiangsu Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Co-Innovation Centre for Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Apr 15; Vol. 258, pp. 117685. Date of Electronic Publication: 2021 Jan 24.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Liberation*
Reactive Oxygen Species*
Cellulose/*chemistry
Dopamine/*pharmacology
Hydrogels/*chemistry
Nanoparticles/*chemistry
Aminolevulinic Acid/pharmacology ; Antineoplastic Agents/pharmacology ; Apoptosis ; Biocompatible Materials/chemistry ; Cell Adhesion ; Cell Survival ; Chemistry, Pharmaceutical/methods ; Drug Delivery Systems ; Humans ; Hydrogen Peroxide ; Hydrogen-Ion Concentration ; Hydroxyl Radical ; Iron/chemistry ; MCF-7 Cells ; Microscopy, Electron, Transmission ; Polymers/chemistry ; Polysaccharides/chemistry ; Thermogravimetry
Czasopismo naukowe

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