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Tytuł :
Up-down regulation of HIF-1α in cancer progression.
Autorzy :
Rashid M; Department of Molecular Medicine, School of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran.
Zadeh LR; Department of Molecular Medicine, School of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran.
Baradaran B; Department of Molecular Medicine, School of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Molavi O; Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Ghesmati Z; Department of Medical Biotechnology, School of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran.
Sabzichi M; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.
Ramezani F; Department of Molecular Medicine, School of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
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Źródło :
Gene [Gene] 2021 Sep 25; Vol. 798, pp. 145796. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Hypoxia-Inducible Factor 1, alpha Subunit/*physiology
Neoplasms/*genetics
Animals ; Disease Progression ; Down-Regulation ; Humans ; Neoplasms/physiopathology ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Inhibition of Long Noncoding RNA SNHG20 Improves Angiotensin II-Induced Cardiac Fibrosis and Hypertrophy by Regulating the MicroRNA 335/ Galectin-3 Axis.
Autorzy :
Li M; Department of Cardiology, The Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Qi C; Department of Cardiology, The Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Song R; Department of Cardiology, The Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Xiong C; Department of Cardiology, The Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Zhong X; Department of Cardiology, The Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Song Z; Department of Cardiology, The Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Ning Z; Shanghai University of Medicine & Health Sciences, Zhoupu Hospital, Shanghai, China.
Song X; Shanghai University of Medicine & Health Sciences, Zhoupu Hospital, Shanghai, China.
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Źródło :
Molecular and cellular biology [Mol Cell Biol] 2021 Aug 24; Vol. 41 (9), pp. e0058020. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Cardiomegaly/*genetics
Galectin 3/*genetics
MicroRNAs/*genetics
Myocardium/*pathology
RNA, Long Noncoding/*metabolism
Angiotensin II ; Animals ; Base Sequence ; Cardiotonic Agents/metabolism ; Cell Line ; Down-Regulation/genetics ; Fibrosis ; Galectin 3/metabolism ; Mice, Inbred C57BL ; MicroRNAs/metabolism ; Myocytes, Cardiac/metabolism ; RNA, Long Noncoding/genetics ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Identification of calmodulin-like protein 5 as tumor-suppressor gene silenced during early stage of carcinogenesis in squamous cell carcinoma of uterine cervix.
Autorzy :
Kitazawa S; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.
Takaoka Y; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.
Ueda Y; Department of Molecular Pathology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.; Division of Diagnostic Pathology, Ehime University Hospital, Toon City, Ehime, Japan.
Kitazawa R; Division of Diagnostic Pathology, Ehime University Hospital, Toon City, Ehime, Japan.
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Źródło :
International journal of cancer [Int J Cancer] 2021 Sep 15; Vol. 149 (6), pp. 1358-1368. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Down-Regulation*
Calcium-Binding Proteins/*genetics
Carcinoma, Squamous Cell/*pathology
Kruppel-Like Transcription Factors/*metabolism
Transcription Factors/*metabolism
Tumor Suppressor Proteins/*metabolism
Uterine Cervical Neoplasms/*pathology
Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Cell Line, Tumor ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; HL-60 Cells ; Humans ; Neoplasm Staging ; Promoter Regions, Genetic ; Protein Transport ; Transcription, Genetic ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Down-regulated MicroRNAs in Gastric Carcinoma May Be Targets for Therapeutic Intervention and Replacement Therapy.
Autorzy :
Weidle UH; Large Molecule Research, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Munich, Penzberg, Germany.
Birzele F; Pharmaceutical Sciences, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.
Auslaender S; Large Molecule Research, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Munich, Penzberg, Germany.
Brinkmann U; Large Molecule Research, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Munich, Penzberg, Germany; .
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4185-4202. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Down-Regulation*
MicroRNAs/*genetics
Stomach Neoplasms/*genetics
Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Regulatory Networks ; Humans ; Molecular Targeted Therapy ; Stomach Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
Jagged-1 Expression Level Is Correlated With Recurrence of Stage III Colorectal Cancer in Patients Receiving Adjuvant Chemotherapy.
Autorzy :
Kim HB; Department of Premedical Course, Chosun University School of Medicine, Gwangju, Republic of Korea.
Lee SB; Department of Internal Medicine, Hemato-oncology, Chosun University Hospital, Gwangju, Republic of Korea.
Kim SJ; Department of Internal Medicine, Gastroentelogy, Chosun University Hospital, Gwangju, Republic of Korea.
Lee HJ; Department of Internal Medicine, Hemato-oncology, Chosun University Hospital, Gwangju, Republic of Korea.
Park SG; Department of Internal Medicine, Hemato-oncology, Chosun University Hospital, Gwangju, Republic of Korea; .
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4645-4650.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Colorectal Neoplasms/*drug therapy
Jagged-1 Protein/*metabolism
Neoplasm Recurrence, Local/*epidemiology
Aged ; Biomarkers, Tumor/metabolism ; Chemotherapy, Adjuvant ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/metabolism ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Clinical Significance of Chemokine Receptor CXCR4 and CCR7 mRNA Expression in Patients With Colorectal Cancer.
Autorzy :
Nagasawa S; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.; Department of Surgery, Yokohama City University, Yokohama, Japan.
Tsuchida K; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.; Department of Surgery, Yokohama City University, Yokohama, Japan.
Shiozawa M; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Hiroshima Y; Kanagawa Cancer Center Research Institute, Yokohama, Japan.
Kimura Y; Advanced Medical Research Center, Yokohama City University, Yokohama, Japan.
Hashimoto I; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Watanabe H; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Kano K; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Numata M; Department of Surgery, Yokohama City University, Yokohama, Japan.
Aoyama T; Department of Surgery, Yokohama City University, Yokohama, Japan.
Sato S; Department of Surgery, Yokohama City University, Yokohama, Japan.
Yamada T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Tamagawa H; Department of Surgery, Yokohama City University, Yokohama, Japan.
Yamamoto N; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Ogata T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Morinaga S; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Yukawa N; Department of Surgery, Yokohama City University, Yokohama, Japan.
Rino Y; Department of Surgery, Yokohama City University, Yokohama, Japan.
Masuda M; Department of Surgery, Yokohama City University, Yokohama, Japan.
Saeki H; Department of Gastrointestinal Surgery, Gunma University, Maebashi, Japan.
Miyagi Y; Kanagawa Cancer Center Research Institute, Yokohama, Japan.
Oshima T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan; .
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4489-4495.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Colorectal Neoplasms/*surgery
Gene Expression Profiling/*methods
Receptors, CCR7/*genetics
Receptors, CXCR4/*genetics
Aged ; Biomarkers, Tumor/genetics ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Prognosis ; Survival Analysis ; Treatment Outcome ; Tumor Burden
Czasopismo naukowe
Tytuł :
BAI1 as a Prognostic Marker of Clear Cell Renal Cell Carcinoma (ccRCC).
Autorzy :
Pesta M; Department of Biology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.; Laboratory of Immunoanalysis, University Hospital in Pilsen, Pilsen, Czech Republic.
Travnicek I; Department of Urology, University Hospital in Pilsen, Pilsen, Czech Republic.
Kulda V; Department of Medical Chemistry and Biochemistry, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic; .
Windrichova J; Laboratory of Immunoanalysis, University Hospital in Pilsen, Pilsen, Czech Republic.; Department of Medical Chemistry and Biochemistry, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.
Rezackova H; Laboratory of Immunoanalysis, University Hospital in Pilsen, Pilsen, Czech Republic.
Houfkova K; Department of Biology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.
Macanova T; Department of Biology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.
Bendova B; Department of Urology, University Hospital in Pilsen, Pilsen, Czech Republic.
Nestorova A; Department of Medical Chemistry and Biochemistry, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.
Hes O; Department of Pathology, University Hospital in Pilsen, Pilsen, Czech Republic.
Hora M; Department of Urology, University Hospital in Pilsen, Pilsen, Czech Republic.
Topolcan O; Laboratory of Immunoanalysis, University Hospital in Pilsen, Pilsen, Czech Republic.
Polivka J; Laboratory of Immunoanalysis, University Hospital in Pilsen, Pilsen, Czech Republic.; Department of Histology and Embryology, Charles University, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4463-4470.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Angiogenic Proteins/*genetics
Biomarkers, Tumor/*genetics
Carcinoma, Renal Cell/*genetics
Gene Expression Profiling/*methods
Kidney Neoplasms/*genetics
Receptors, G-Protein-Coupled/*genetics
Carcinoma, Renal Cell/mortality ; Carcinoma, Renal Cell/surgery ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Kidney Neoplasms/mortality ; Kidney Neoplasms/surgery ; Male ; Oligonucleotide Array Sequence Analysis ; Prognosis ; Regression Analysis ; Survival Analysis
Czasopismo naukowe
Tytuł :
Induction of Cross-resistance to ABCB1 Substrates in Venetoclax-resistant Human Leukemia HL60 Cells.
Autorzy :
Nakayama Y; Department of Pharmaceutics, Kobe University Graduate School of Medicine, Kobe, Japan.; Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Japan.
Takara K; Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Japan; .; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Hyogo University of Health Sciences, Kobe, Japan.
Minegaki T; Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan.
Yamamoto K; Department of Pharmaceutics, Kobe University Graduate School of Medicine, Kobe, Japan.; Department of Pharmacy, Kobe University Hospital, Kobe, Japan.
Omura T; Department of Pharmaceutics, Kobe University Graduate School of Medicine, Kobe, Japan.; Department of Pharmacy, Kobe University Hospital, Kobe, Japan.
Yano I; Department of Pharmaceutics, Kobe University Graduate School of Medicine, Kobe, Japan.; Department of Pharmacy, Kobe University Hospital, Kobe, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4239-4248. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Neoplasm*
Up-Regulation*
Leukemia, Promyelocytic, Acute/*genetics
ATP Binding Cassette Transporter, Subfamily B/genetics ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Cell Proliferation ; Cell Survival ; Gene Expression Regulation, Neoplastic ; HL-60 Cells ; Humans ; Sulfonamides/pharmacology
Czasopismo naukowe
Tytuł :
HGF-mediated Up-regulation of PHLDA2 Is Associated With Apoptosis in Gastric Cancer.
Autorzy :
Koh SA; Departments of Hematology-Oncology, College of Medicine, Yeungnam University, Daegu, Republic of Korea.
Lee KH; Departments of Hematology-Oncology, College of Medicine, Yeungnam University, Daegu, Republic of Korea .
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4377-4385.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Hepatocyte Growth Factor/*metabolism
Nuclear Proteins/*metabolism
Stomach Neoplasms/*metabolism
Apoptosis ; Cell Line, Tumor ; Chromones/pharmacology ; Flavonoids/pharmacology ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Knockdown Techniques ; Humans ; Imidazoles ; Morpholines/pharmacology ; Nuclear Proteins/genetics ; Oligonucleotide Array Sequence Analysis ; Pyridines
Czasopismo naukowe
Tytuł :
Pathological Roles of Prostaglandin E2-specific E-type Prostanoid Receptors in Hormone-sensitive and Castration-resistant Prostate Cancer.
Autorzy :
Miyata Y; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan .
Masato M; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Mukae Y; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Nakamura Y; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Matsuda T; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Harada J; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Mitsunari K; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Matsuo T; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Ohba K; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Sakai H; Department of Urology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4333-4341.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Prostatic Neoplasms, Castration-Resistant/*pathology
Receptors, Prostaglandin E, EP4 Subtype/*metabolism
Vascular Endothelial Growth Factor A/*metabolism
Apoptosis ; Cell Proliferation ; Cell Survival ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Neoplasm Grading ; Neoplasm Staging ; Prostatic Neoplasms, Castration-Resistant/metabolism
Czasopismo naukowe
Tytuł :
Analysis of Mesencephalic Astrocyte-derived Neurotrophic Factor in Multiple Myeloma.
Autorzy :
Dernoncourt A; Department of Internal Medicine and RECIF, Amiens-Picardie University Medical Center, Amiens, France; .
Sauzay C; Laboratory of Biochemistry and Team CHIMERE, EA 7516, Amiens-Picardie University Medical Center, Amiens, France.
Schmidt J; Department of Internal Medicine and RECIF, Amiens-Picardie University Medical Center, Amiens, France.
Louandre C; Laboratory of Biochemistry and Team CHIMERE, EA 7516, Amiens-Picardie University Medical Center, Amiens, France.
Gomila C; Laboratory of Biochemistry and Team CHIMERE, EA 7516, Amiens-Picardie University Medical Center, Amiens, France.
Duhaut P; Department of Internal Medicine and RECIF, Amiens-Picardie University Medical Center, Amiens, France.
Herpe YE; Biobank of Picardie, Amiens-Picardie University Medical Center, Amiens, France.
Saidak Z; Laboratory of Molecular Oncobiology, Center of Human Biology, Amiens-Picardie University Medical Center, Amiens, France.
Galmiche A; Laboratory of Biochemistry and Team CHIMERE, EA 7516, Amiens-Picardie University Medical Center, Amiens, France.
Salle V; Department of Internal Medicine and RECIF, Amiens-Picardie University Medical Center, Amiens, France.
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4305-4312.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Up-Regulation*
Monoclonal Gammopathy of Undetermined Significance/*metabolism
Multiple Myeloma/*metabolism
Nerve Growth Factors/*blood
Nerve Growth Factors/*genetics
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Cell Line, Tumor ; Computer Simulation ; Gene Expression Regulation, Neoplastic ; Humans ; Middle Aged ; Monoclonal Gammopathy of Undetermined Significance/blood ; Monoclonal Gammopathy of Undetermined Significance/genetics ; Multiple Myeloma/blood ; Multiple Myeloma/genetics ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Tytuł :
Cystathionine Gamma-Lyase Is Increased in Testicular Seminomas, Embryonal, and Yolk Sac Tumors.
Autorzy :
Ozluk E; Department of Pathology and Translational Pathobiology, LSU Health Sciences Center Shreveport, Shreveport, LA, U.S.A.
Patel S; Head and Neck Oncologic/Microvascular Reconstructive Surgery, Department of Oral and Maxillofacial/Head and Neck Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, U.S.A.
Coppola D; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, U.S.A.
Ghali G; Head and Neck Oncologic/Microvascular Reconstructive Surgery, Department of Oral and Maxillofacial/Head and Neck Surgery, Louisiana State University Health Sciences Center, Shreveport, LA, U.S.A.
Cotelingam JD; Department of Pathology and Translational Pathobiology, LSU Health Sciences Center Shreveport, Shreveport, LA, U.S.A.
Kevil CG; Department of Pathology and Translational Pathobiology, LSU Health Sciences Center Shreveport, Shreveport, LA, U.S.A.
Shackelford RE; Department of Pathology and Translational Pathobiology, LSU Health Sciences Center Shreveport, Shreveport, LA, U.S.A.; .
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Źródło :
Anticancer research [Anticancer Res] 2021 Sep; Vol. 41 (9), pp. 4211-4214. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Carcinoma, Embryonal/*metabolism
Cystathionine gamma-Lyase/*metabolism
Endodermal Sinus Tumor/*metabolism
Testicular Neoplasms/*metabolism
Case-Control Studies ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Seminoma ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Estrogen suppresses HOXB2 expression via ERα in breast cancer cells.
Autorzy :
Kumar A; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Dhillon A; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Manjegowda MC; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Singh N; Molecular and Cellular Biology Laboratory, ICMR-National Institute of Research in Reproductive Health, Indian Council of Medical Research (ICMR), Parel 400012, Mumbai, India.
Mary DJSJ; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Kumar S; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Modi D; Molecular and Cellular Biology Laboratory, ICMR-National Institute of Research in Reproductive Health, Indian Council of Medical Research (ICMR), Parel 400012, Mumbai, India.
Limaye AM; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India. Electronic address: .
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Źródło :
Gene [Gene] 2021 Aug 20; Vol. 794, pp. 145746. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*
Breast Neoplasms/*genetics
Estrogen Receptor alpha/*genetics
Homeodomain Proteins/*genetics
Phenols/*administration & dosage
Pyrazoles/*administration & dosage
Transcription Factors/*genetics
Animals ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MCF-7 Cells ; Mice ; Neoplasm Transplantation ; Phenols/pharmacology ; Promoter Regions, Genetic ; Pyrazoles/pharmacology
Czasopismo naukowe
Tytuł :
Pattern of TAAR5 Expression in the Human Brain Based on Transcriptome Datasets Analysis.
Autorzy :
Vaganova AN; Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
Murtazina RZ; Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
Shemyakova TS; Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
Prjibelski AD; Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
Katolikova NV; Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
Gainetdinov RR; Institute of Translational Biomedicine, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.; St. Petersburg University Hospital, St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 16; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*
Brain/*metabolism
Depressive Disorder, Major/*genetics
Down Syndrome/*genetics
Encephalitis, Viral/*genetics
HIV Infections/*complications
Receptors, G-Protein-Coupled/*genetics
Databases, Genetic ; Encephalitis, Viral/etiology ; Gene Expression Profiling ; Gene Expression Regulation ; HIV Infections/genetics ; Humans ; Oligonucleotide Array Sequence Analysis ; Sequence Analysis, RNA ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor.
Autorzy :
Lai ZY; Department of Medical Science & Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.
Tsai KY; Department of Medical Science & Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.
Chang SJ; Department of Obstetrics and Gynecology, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan.
Chuang YJ; Department of Medical Science & Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 16; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gain of Function Mutation*
Up-Regulation*
Carcinoma, Ovarian Epithelial/*genetics
Cystadenocarcinoma, Serous/*genetics
Proto-Oncogene Proteins c-akt/*metabolism
Tumor Suppressor Protein p53/*genetics
Carcinoma, Ovarian Epithelial/drug therapy ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cystadenocarcinoma, Serous/drug therapy ; ErbB Receptors/antagonists & inhibitors ; Female ; Gefitinib/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Phosphorylation/drug effects ; Protein Transport/drug effects ; Proto-Oncogene Proteins c-mdm2/antagonists & inhibitors ; Signal Transduction/drug effects ; Tryptamines/pharmacology
Czasopismo naukowe
Tytuł :
Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification.
Autorzy :
Walker H; Health Sciences Centre, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4L8, Canada.
Taiyab A; Health Sciences Centre, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4L8, Canada.
Deschamps P; Health Sciences Centre, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4L8, Canada.
Williams T; Department of Craniofacial Biology, University of Colorado, Mail Stop 8120, RC1-S, Rm L18 11111, 12801 E. 17th Ave, Aurora, CO 80045, USA.
West-Mays JA; Health Sciences Centre, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4L8, Canada.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 13; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*
Gene Deletion*
Bone Morphogenetic Protein 4/*metabolism
Epithelium, Corneal/*abnormalities
Transcription Factor AP-2/*genetics
Animals ; Bone Morphogenetic Protein 4/genetics ; Cell Differentiation ; Epithelium, Corneal/metabolism ; Female ; Gene Expression Regulation, Developmental ; Gene Knockout Techniques ; Keratin-12/metabolism ; Keratin-15/metabolism ; Male ; Mice ; Neural Crest/metabolism ; Phenotype ; Transcription Factor AP-2/metabolism ; Wnt Signaling Pathway
Czasopismo naukowe
Tytuł :
Genotoxic stress and viral infection induce transient expression of APOBEC3A and pro-inflammatory genes through two distinct pathways.
Autorzy :
Oh S; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Bournique E; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Bowen D; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Jalili P; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Sanchez A; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Ward I; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Dananberg A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Manjunath L; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Tran GP; Department of Microbiology and Molecular Genetics, UCI Center for Virus Research, School of Medicine, University of California Irvine, Irvine, California, USA.
Semler BL; Department of Microbiology and Molecular Genetics, UCI Center for Virus Research, School of Medicine, University of California Irvine, Irvine, California, USA.
Maciejowski J; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Seldin M; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA.
Buisson R; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, California, USA. .; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California, USA. .; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University of California Irvine, Irvine, California, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 13; Vol. 12 (1), pp. 4917. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Gene Expression Regulation*
Cytidine Deaminase/*genetics
Immunity/*genetics
Proteins/*genetics
Signal Transduction/*physiology
Cell Line ; Cell Line, Tumor ; Cytidine Deaminase/metabolism ; Host-Pathogen Interactions ; Humans ; Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; THP-1 Cells ; Transcription Factor RelA/metabolism ; Up-Regulation ; Viruses/growth & development
Czasopismo naukowe
Tytuł :
TNFα and Immune Checkpoint Inhibition: Friend or Foe for Lung Cancer?
Autorzy :
Benoot T; Laboratory for Molecular and Cellular Therapy, Department Biomedical Science, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Piccioni E; Laboratory for Molecular and Cellular Therapy, Department Biomedical Science, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
De Ridder K; Laboratory for Molecular and Cellular Therapy, Department Biomedical Science, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
Goyvaerts C; Laboratory for Molecular and Cellular Therapy, Department Biomedical Science, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussels, Belgium.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 13; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Down-Regulation*
Immune Checkpoint Inhibitors/*therapeutic use
Lung Neoplasms/*genetics
Tumor Necrosis Factor-alpha/*genetics
ADAM17 Protein/genetics ; Cell Survival ; Gene Expression Regulation, Neoplastic ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Receptors, Tumor Necrosis Factor, Type II/genetics ; Receptors, Tumor Necrosis Factor, Type II/metabolism ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
LncRNA MIR31HG Drives Oncogenicity by Inhibiting the Limb-Bud and Heart Development Gene ( LBH ) during Oral Carcinoma.
Autorzy :
Chang KW; Department of Dentistry, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Stomatology, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Hung WW; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Chou CH; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Tu HF; Department of Dentistry, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Dentistry, National Yang Ming Chiao Tung Hospital, Yilan 260, Taiwan.
Chang SR; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Liu YC; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Liu CJ; Department of Dentistry, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Dentistry, Taipei MacKay Memorial Hospital, Taipei 104, Taiwan.
Lin SC; Department of Dentistry, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Institute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Stomatology, Taipei Veterans General Hospital, Taipei 112, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 04; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Carcinoma, Squamous Cell/*genetics
Mouth Neoplasms/*genetics
RNA, Long Noncoding/*genetics
Transcription Factors/*genetics
Carcinogenesis/genetics ; Carcinogenesis/pathology ; Carcinoma, Squamous Cell/pathology ; Disease Progression ; Humans ; Mouth Neoplasms/pathology ; Up-Regulation
Czasopismo naukowe
Tytuł :
The small GTP-binding protein TaRop10 interacts with TaTrxh9 and functions as a negative regulator of wheat resistance against the stripe rust.
Autorzy :
Shi B; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China.
Wang J; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China; School of Life Science, Shanxi Datong University, Datong, Shanxi 037009, China.
Gao H; Institute of Plant Protection, Xinjiang Academy of Agricultural Sciences / Key Laboratory of Integrated Pest Management on Crop in Northwestern Oasis, Ministry of Agriculture and Rural Affairs, Urumqi, Xinjiang 830091, China.
Yang Q; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China.
Wang Y; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China.
Day B; Department of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI, United States; Plant Resilience Institute, Michigan State University, East Lansing, MI, United States. Electronic address: .
Ma Q; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: .
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Źródło :
Plant science : an international journal of experimental plant biology [Plant Sci] 2021 Aug; Vol. 309, pp. 110937. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Plant*
Arabidopsis Proteins/*metabolism
Disease Resistance/*genetics
GTP-Binding Proteins/*metabolism
Plant Diseases/*immunology
Plant Proteins/*metabolism
Puccinia/*physiology
Triticum/*enzymology
Arabidopsis Proteins/genetics ; Down-Regulation ; GTP-Binding Proteins/genetics ; Gene Silencing ; Plant Diseases/microbiology ; Plant Proteins/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Stress, Physiological ; Triticum/genetics
Czasopismo naukowe

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