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Tytuł:
Culture and expansion of murine proximal airway basal stem cells.
Autorzy:
Wu M; Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China.; Fujian Key Laboratory of Lung Stem Cells, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China.
Zhang X; Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China.; Fujian Key Laboratory of Lung Stem Cells, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China.
Tu Y; Department of Pathology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China.
Cheng W; Fujian Key Laboratory of Lung Stem Cells, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China.
Zeng Y; Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China. zeng_yi_.; Fujian Key Laboratory of Lung Stem Cells, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, People's Republic of China. zeng_yi_.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, Shandong Province, People's Republic of China. zeng_yi_.
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2024 Jan 30; Vol. 15 (1), pp. 26. Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
rho-Associated Kinases*
Stem Cells*
Animals ; Mice ; Amides/pharmacology ; Pyridines/pharmacology ; Cell Differentiation ; Cell Proliferation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation.
Autorzy:
Zhang Y; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. .
Li N; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan.
Kobayashi S; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 22; Vol. 22 (1), pp. 58. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:
Muscle, Smooth, Vascular*
Paxillin*
rho-Associated Kinases*
Animals ; Humans ; Mice ; Actins ; Mice, Knockout ; Myosin Light Chains ; Phosphorylcholine/analogs & derivatives ; Sphingosine/analogs & derivatives
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia.
Autorzy:
Fayed HS; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.
Bakleh MZ; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.
Ashraf JV; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.
Howarth A; Nuffield Department of Medicine, Target Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK.
Ebner D; Nuffield Department of Medicine, Target Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK.
Al Haj Zen A; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 22; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article
MeSH Terms:
rho-Associated Kinases*/metabolism
Endothelial Cells*/metabolism
Mice ; Animals ; Neovascularization, Physiologic ; Ischemia/metabolism ; Regional Blood Flow ; Hindlimb/pathology ; Disease Models, Animal ; Muscle, Skeletal/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
3D cell segregation geometry and dynamics are governed by tissue surface tension regulation.
Autorzy:
Méhes E; Department of Biological Physics, ELTE Eötvös University, Budapest, Hungary.
Mones E; Department of Biological Physics, ELTE Eötvös University, Budapest, Hungary.
Varga M; Department of Genetics, ELTE Eötvös University, Budapest, Hungary.
Zsigmond Á; Department of Genetics, ELTE Eötvös University, Budapest, Hungary.
Biri-Kovács B; Department of Biochemistry, ELTE Eötvös University, Budapest, Hungary.
Nyitray L; Department of Biochemistry, ELTE Eötvös University, Budapest, Hungary.
Barone V; Center for Marine Biotechnology and Biomedicine, University of California San Diego, La Jolla, CA, USA.; Institute of Science and Technology Austria, Klosterneuburg, Austria.
Krens G; Institute of Science and Technology Austria, Klosterneuburg, Austria.
Heisenberg CP; Institute of Science and Technology Austria, Klosterneuburg, Austria.
Vicsek T; Department of Biological Physics, ELTE Eötvös University, Budapest, Hungary. .
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Źródło:
Communications biology [Commun Biol] 2023 Aug 04; Vol. 6 (1), pp. 817. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Actomyosin*/metabolism
rho-Associated Kinases*/metabolism
Animals ; Surface Tension ; Zebrafish/metabolism ; Cell Separation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synergy by Ristocetin and CXCL12 in Human Platelet Activation: Divergent Regulation by Rho/Rho-Kinase and Rac.
Autorzy:
Enomoto Y; Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Onuma T; Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Hori T; Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.; Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.; Department of Metabolic Research, Research Institute, National Center for Geriatrics and Gerontology, Obu 474-8511, Aichi, Japan.
Tanabe K; Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Ueda K; Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Mizutani D; Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Doi T; Department of Emergency and Disaster Medicine, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Matsushima-Nishiwaki R; Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Ogura S; Department of Emergency and Disaster Medicine, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Iida H; Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Iwama T; Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.
Kozawa O; Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.; Department of Metabolic Research, Research Institute, National Center for Geriatrics and Gerontology, Obu 474-8511, Aichi, Japan.
Tokuda H; Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1193, Aichi, Japan.; Department of Metabolic Research, Research Institute, National Center for Geriatrics and Gerontology, Obu 474-8511, Aichi, Japan.; Department of Clinical Laboratory, National Center for Geriatrics and Gerontology, Obu 474-8511, Aichi, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 03; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 03.
Typ publikacji:
Journal Article
MeSH Terms:
rho-Associated Kinases*/metabolism
Ristocetin*/metabolism
Ristocetin*/pharmacology
Humans ; Blood Platelets/metabolism ; CD40 Ligand/metabolism ; Chemokine CXCL12/pharmacology ; Chemokine CXCL12/metabolism ; Phosphorylation ; Platelet Activation ; Platelet Aggregation ; Platelet Glycoprotein GPIb-IX Complex/metabolism ; von Willebrand Factor/metabolism ; rac GTP-Binding Proteins/drug effects ; rac GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Rho-Associated Kinase (Rock) Inhibitors (Alternative to Y-27632) on Primary Human Corneal Endothelial Cells.
Autorzy:
Peh GSL; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.; Singhealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme , Duke-NUS Graduate Medical School, Singapore 169857, Singapore.
Bandeira F; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.; Department of Ophthalmology and Visual Sciences, Federal University of São Paulo, São Paulo 04023-062, Brazil.; Corneal and External Diseases Department, São Gonçalo Eye Hospital, Rio de Janeiro 24421-005, Brazil.
Neo D; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Adnan K; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Hartono Y; Bioinformatics Institute, A*STAR, 30 Biopolis Street, Matrix #07-01, Singapore 138671, Singapore.
Ong HS; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.; Singhealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme , Duke-NUS Graduate Medical School, Singapore 169857, Singapore.; Singapore National Eye Centre, Singapore 168751, Singapore.
Naso S; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Venkatraman A; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Gomes JAP; Department of Ophthalmology and Visual Sciences, Federal University of São Paulo, São Paulo 04023-062, Brazil.
Kocaba V; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.; Netherlands Institute for Innovative Ocular Surgery, 3071AA Rotterdam, The Netherlands.
Mehta JS; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore 169856, Singapore.; Singhealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme , Duke-NUS Graduate Medical School, Singapore 169857, Singapore.; Singapore National Eye Centre, Singapore 168751, Singapore.
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Źródło:
Cells [Cells] 2023 May 03; Vol. 12 (9). Date of Electronic Publication: 2023 May 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelium, Corneal*/metabolism
rho-Associated Kinases*/metabolism
Humans ; Endothelial Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ripasudil as a Potential Therapeutic Agent in Treating Secondary Glaucoma in HTLV-1-Uveitis: An In Vitro Analysis.
Autorzy:
Yang M; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Kamoi K; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Zong Y; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Zhang J; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Zou Y; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Ohno-Matsui K; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 12; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Human T-lymphotropic virus 1*
Glaucoma*/drug therapy
Glaucoma*/etiology
Uveitis*
Isoquinolines*
Sulfonamides*
Adult ; Humans ; NF-kappa B ; Cytokines/therapeutic use ; Interleukin-6 ; rho-Associated Kinases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hypothermia Inhibits Dexmedetomidine-Induced Contractions in Isolated Rat Aortae.
Autorzy:
Lee S; Department of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital, Changwon-si 51472, Gyeongsangnam-do, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.; Institute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Hwang Y; Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Park KE; Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Bae S; Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Ok SH; Department of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital, Changwon-si 51472, Gyeongsangnam-do, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.; Institute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Ahn SH; Institute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Sim G; Institute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Bae M; Department of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Sohn JT; Institute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 05; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Dexmedetomidine*/pharmacology
Hypothermia*/metabolism
Rats ; Animals ; rho-Associated Kinases/metabolism ; NG-Nitroarginine Methyl Ester/pharmacology ; Calcium/metabolism ; Protein Kinase C/metabolism ; Endothelium, Vascular/metabolism ; Muscle Contraction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells.
Autorzy:
Bachtler N; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Torres S; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Ortiz C; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Schierwagen R; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Tyc O; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Hieber C; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Berres ML; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Meier C; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Kraus N; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Zeuzem S; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
Nijmeijer B; LinXis BV, Amsterdam, The Netherlands.
Pronk S; LinXis BV, Amsterdam, The Netherlands.
Trebicka J; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.; European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain.
Klein S; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
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Źródło:
PloS one [PLoS One] 2023 Jan 31; Vol. 18 (1), pp. e0270288. Date of Electronic Publication: 2023 Jan 31 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
rho-Associated Kinases*/metabolism
Signal Transduction*
Animals ; Humans ; Mice ; Cells, Cultured ; Hepatic Stellate Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Short-Term Treatment with Rho-Associated Kinase Inhibitor Preserves Keratinocyte Stem Cell Characteristics In Vitro.
Autorzy:
Jayarajan V; Infection, Immunity and Inflammation Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
Hall GT; Genetics and Genomic Medicine Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, 20 Guilford Street, London WC1N 1DZ, UK.
Xenakis T; Genetics and Genomic Medicine Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, 20 Guilford Street, London WC1N 1DZ, UK.
Bulstrode N; Department of Plastic Surgery, Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK.
Moulding D; Light Microscopy Core Facility, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
Castellano S; Genetics and Genomic Medicine Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, 20 Guilford Street, London WC1N 1DZ, UK.; UCL Genomics, Zayed Centre for Research into Rare Disease in Children, 20 Guilford Street, London WC1N 1DZ, UK.
Di WL; Infection, Immunity and Inflammation Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
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Źródło:
Cells [Cells] 2023 Jan 17; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
rho-Associated Kinases*
Keratinocytes*
Cells, Cultured ; Stem Cells ; Epidermis ; Protein Kinase Inhibitors/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sphingosylphosphorylcholine (SPC), a Causative Factor of SPC-Induced Vascular Smooth Muscle Cells Contraction, Is Taken Up via Endocytosis.
Autorzy:
Tsurudome N; The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
Minami Y; The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.; Department of Food Science & Biotechnology, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
Kajiya K; The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.; Department of Food Science & Biotechnology, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan.
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Źródło:
Cells [Cells] 2023 Jan 09; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Muscle, Smooth, Vascular*/metabolism
rho-Associated Kinases*/metabolism
Muscle Contraction/physiology ; Endocytosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety and Efficacy of the Rho-Kinase Inhibitor (Ripasudil) in Bleb Needling after Trabeculectomy: A Prospective Multicenter Study.
Autorzy:
Mizuno, Yu (AUTHOR)
Komatsu, Kaori (AUTHOR)
Tokumo, Kana (AUTHOR)
Okada, Naoki (AUTHOR)
Onoe, Hiromitsu (AUTHOR)
Okumichi, Hideaki (AUTHOR)
Hirooka, Kazuyuki (AUTHOR)
Aoki, Gaku (AUTHOR)
Miura, Yukiko (AUTHOR)
Kiuchi, Yoshiaki (AUTHOR)
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Źródło:
Journal of Clinical Medicine. Jan2024, Vol. 13 Issue 1, p75. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
圣草酚改善5×FAD 小鼠认知功能并调控Nogo-A/NgR/ROCK2 信号通路.
Autorzy:
李梦迪
李 娜
郭敏芳
孟 涛
于婧文
李雁冰
马存根
尉杰忠
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Alternatywny tytuł:
Eriodictyol improves cognitive function of 5×FAD mice by regulating Nogo-A/NgR/ROCK2 signaling pathway.
Źródło:
Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu. 11/18/2023, Vol. 27 Issue 32, p5097-5102. 6p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Rho-Kinase/ROCK Phosphorylates PSD-93 Downstream of NMDARs to Orchestrate Synaptic Plasticity.
Autorzy:
Hossen E; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.; Division of Cell Biology, International Center for Brain Science, Fujita Health University, Toyoake 470-1192, Japan.
Funahashi Y; Division of Cell Biology, International Center for Brain Science, Fujita Health University, Toyoake 470-1192, Japan.
Faruk MO; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.; Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Dhaka, Dhaka 1000, Bangladesh.
Ahammad RU; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Amano M; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.
Yamada K; Department of Neuropsychopharmacology and Hospital Pharmacy, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.
Kaibuchi K; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Nagoya 466-8550, Japan.; Division of Cell Biology, International Center for Brain Science, Fujita Health University, Toyoake 470-1192, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 26; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
rho-Associated Kinases*/metabolism
Receptors, N-Methyl-D-Aspartate*/metabolism
Chromatography, Liquid ; Tandem Mass Spectrometry ; Neuronal Plasticity/physiology ; Synaptic Transmission/physiology ; Disks Large Homolog 4 Protein/metabolism ; Synapses/metabolism ; Hippocampus/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel Dual AChE and ROCK2 Inhibitor Induces Neurogenesis via PTEN/AKT Pathway in Alzheimer's Disease Model.
Autorzy:
Moreira NCDS; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14049-900, Brazil.
Tamarozzi ER; Department of Biotechnology, School of Arts, Sciences and Humanities-USP, São Paulo 03828-000, Brazil.
Lima JEBF; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14049-900, Brazil.
Piassi LO; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14049-900, Brazil.
Carvalho I; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo-USP, Ribeirão Preto 14040-900, Brazil.
Passos GA; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14049-900, Brazil.; Laboratory of Genetics and Molecular Biology, Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14049-900, Brazil.
Sakamoto-Hojo ET; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14049-900, Brazil.; Department of Biology, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo-USP, Ribeirão Preto 14040-901, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 26; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 26.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Cholinesterase Inhibitors*/chemistry
Neuroblastoma*/drug therapy
Neurodegenerative Diseases*/drug therapy
rho-Associated Kinases*/antagonists & inhibitors
Humans ; Acetylcholinesterase/metabolism ; Donepezil/pharmacology ; PTEN Phosphohydrolase ; Tacrine/chemistry
Czasopismo naukowe
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Tytuł:
Novel ROCK Inhibitors, Sovesudil and PHP-0961, Enhance Proliferation, Adhesion and Migration of Corneal Endothelial Cells.
Autorzy:
Kim KW; Department of Ophthalmology, Hallym University Medical Center, College of Medicine, Hallym University, Seoul 07441, Republic of Korea.
Shin YJ; Department of Ophthalmology, Hallym University Medical Center, College of Medicine, Hallym University, Seoul 07441, Republic of Korea.; Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07441, Republic of Korea.
Lee SCS; pH Pharma Co., Ltd., B-1009, U-Space, 670 Daewangpangyo-ro, Bundang-gu, Seongnam-si 13494, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 24; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells*/drug effects
Endothelium, Corneal*/cytology
Protein Kinase Inhibitors*/pharmacology
rho-Associated Kinases*/antagonists & inhibitors
Animals ; Humans ; Cell Proliferation ; Cells, Cultured ; Swine ; Cell Adhesion ; Cell Movement
Czasopismo naukowe
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Wyświetlanie 1-20 z 2301

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