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Wyszukujesz frazę ""rosuvastatin"" wg kryterium: Temat


Tytuł :
UPLC-MS/MS method for the simultaneous quantification of pravastatin, fexofenadine, rosuvastatin, and methotrexate in a hepatic uptake model and its application to the possible drug-drug interaction study of triptolide.
Autorzy :
Wu W; New drug screening center, Institute of Pharmaceutical Research, China Pharmaceutical University, Nanjing, China.; Key Laboratory of Drug Quality Control and Pharmacovigilance of Ministry of Education, China Pharmaceutical University, Nanjing, China.
Cheng R; New drug screening center, Institute of Pharmaceutical Research, China Pharmaceutical University, Nanjing, China.; Key Laboratory of Drug Quality Control and Pharmacovigilance of Ministry of Education, China Pharmaceutical University, Nanjing, China.
Jiang Z; New drug screening center, Institute of Pharmaceutical Research, China Pharmaceutical University, Nanjing, China.; Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, China.
Zhang L; Center for Drug Screening and Pharmacodynamics Evaluation, School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
Huang X; New drug screening center, Institute of Pharmaceutical Research, China Pharmaceutical University, Nanjing, China.; Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, China.
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Źródło :
Biomedical chromatography : BMC [Biomed Chromatogr] 2021 Jul; Vol. 35 (7), pp. e5093. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Methotrexate*/analysis
Methotrexate*/pharmacokinetics
Pravastatin*/analysis
Pravastatin*/pharmacokinetics
Rosuvastatin Calcium*/analysis
Rosuvastatin Calcium*/pharmacokinetics
Hepatocytes/*metabolism
Terfenadine/*analogs & derivatives
Animals ; Cells, Cultured ; Chromatography, High Pressure Liquid/methods ; Diterpenes/analysis ; Diterpenes/pharmacokinetics ; Drug Interactions ; Epoxy Compounds/analysis ; Epoxy Compounds/pharmacokinetics ; Linear Models ; Male ; Phenanthrenes/analysis ; Phenanthrenes/pharmacokinetics ; Rats, Wistar ; Reproducibility of Results ; Sensitivity and Specificity ; Tandem Mass Spectrometry/methods ; Terfenadine/analysis ; Terfenadine/pharmacokinetics
Czasopismo naukowe
Tytuł :
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
Autorzy :
Zi L; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Zhou W; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Xu J; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Li J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan, People's Republic of China.
Li N; Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Xu J; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; West China Brain Research Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
You C; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; West China Brain Research Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Wang C; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Tian M; Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.; West China Brain Research Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Apr 20; Vol. 16, pp. 2933-2947. Date of Electronic Publication: 2021 Apr 20 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Hemorrhage/*drug therapy
Drug Carriers/*administration & dosage
Inflammation/*drug therapy
Nanostructures/*chemistry
Rosuvastatin Calcium/*pharmacology
Animals ; Behavior, Animal/drug effects ; Brain Edema/drug therapy ; Brain Edema/pathology ; Cerebral Hemorrhage/pathology ; Disease Models, Animal ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Inflammation/pathology ; Mice ; Micelles ; Microglia/drug effects ; Microglia/pathology ; Nanostructures/administration & dosage ; Polyesters/chemistry ; Polyethylene Glycols/chemistry ; RAW 264.7 Cells ; Rosuvastatin Calcium/administration & dosage
Czasopismo naukowe
Tytuł :
Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains.
Autorzy :
Dulka K; Department of Cell Biology and Molecular Medicine, University of Szeged, 6720 Szeged, Hungary.
Szabo M; Department of Cell Biology and Molecular Medicine, University of Szeged, 6720 Szeged, Hungary.
Lajkó N; Department of Cell Biology and Molecular Medicine, University of Szeged, 6720 Szeged, Hungary.
Belecz I; Department of Medical Biology, University of Szeged, 6720 Szeged, Hungary.
Hoyk Z; Biological Barriers Research Group, Institute of Biophysics, Biological Research Center, Eötvös Loránd Research Network, 6726 Szeged, Hungary.
Gulya K; Department of Cell Biology and Molecular Medicine, University of Szeged, 6720 Szeged, Hungary.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 26; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Epigenesis, Genetic*
Histone Code*
Anticholesteremic Agents/*adverse effects
Brain/*drug effects
Embryo, Mammalian/*drug effects
Rosuvastatin Calcium/*adverse effects
Animals ; Anticholesteremic Agents/pharmacology ; Brain/embryology ; Brain/metabolism ; Female ; Histones/drug effects ; Histones/metabolism ; Methylation ; Rats ; Rats, Sprague-Dawley ; Rosuvastatin Calcium/pharmacology
Czasopismo naukowe
Tytuł :
Protective effect of Rosuvastatin on Azithromycin induced cardiotoxicity in a rat model.
Autorzy :
Mansour BS; Anatomy Department, Faculty of Medicine, Suez Canal University, Egypt.
Salem NA; Anatomy Department, Faculty of Medicine, Suez Canal University, Egypt.
Kader GA; Anatomy Department, Faculty of Medicine, Suez Canal University, Egypt.
Abdel-Alrahman G; Anatomy Department, Faculty of Medicine, Suez Canal University, Egypt.
Mahmoud OM; Anatomy Department, Faculty of Medicine, Suez Canal University, Egypt. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119099. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*adverse effects
Azithromycin/*adverse effects
Cardiotoxicity/*prevention & control
Rosuvastatin Calcium/*pharmacology
Animals ; Anti-Bacterial Agents/administration & dosage ; Antioxidants/administration & dosage ; Antioxidants/pharmacology ; Apoptosis/drug effects ; Azithromycin/administration & dosage ; COVID-19/drug therapy ; Cardiotoxicity/etiology ; Disease Models, Animal ; Glutathione/metabolism ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Inflammation/chemically induced ; Inflammation/prevention & control ; Male ; Malondialdehyde/metabolism ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Rosuvastatin Calcium/administration & dosage
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Effect of atorvastatin versus rosuvastatin on inflammatory biomarkers and LV function in type 2 diabetic patients with dyslipidemia.
Autorzy :
Werida R; Faculty of Pharmacy, Clinical Pharmacy Department, Damanhur University, El- Bahiara, Egypt. Electronic address: .
Khairat I; Faculty of Medicine, Cardiology Department, Tanta University, El-Gharbia, Egypt. Electronic address: .
Khedr NF; Faculty of Pharmacy, Department of Biochemistry, Tanta University, El-Gharbia, Egypt. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Mar; Vol. 135, pp. 111179. Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Atorvastatin/*therapeutic use
Diabetes Mellitus, Type 2/*drug therapy
Dyslipidemias/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Hypertrophy, Left Ventricular/*prevention & control
Inflammation Mediators/*blood
Rosuvastatin Calcium/*therapeutic use
Ventricular Function, Left/*drug effects
Ventricular Remodeling/*drug effects
Atorvastatin/adverse effects ; Biomarkers/blood ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Double-Blind Method ; Dyslipidemias/blood ; Dyslipidemias/diagnosis ; Egypt ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Hypertrophy, Left Ventricular/diagnostic imaging ; Hypertrophy, Left Ventricular/physiopathology ; Lipids/blood ; Male ; Middle Aged ; Prospective Studies ; Rosuvastatin Calcium/adverse effects ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Proteomics-Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight.
Autorzy :
Wegler C; Department of Pharmacy, Uppsala University, Uppsala, Sweden.; DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Prieto Garcia L; DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Klinting S; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Robertsen I; Department of Pharmacy, University of Oslo, Oslo, Norway.
Wiśniewski JR; Biochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Hjelmesaeth J; Morbid Obesity Centre, Department of Medicine, Vestfold Hospital Trust, Tønsberg, Norway.; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Åsberg A; Department of Pharmacy, University of Oslo, Oslo, Norway.; Department of Transplantation Medicine, Oslo University Hospital-Rikshospitalet, Oslo, Norway.
Jansson-Löfmark R; DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Andersson TB; DMPK, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Artursson P; Department of Pharmacy and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Mar; Vol. 109 (3), pp. 762-771. Date of Electronic Publication: 2020 Oct 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Weight*
Proteomics*
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*blood
Liver/*metabolism
Liver-Specific Organic Anion Transporter 1/*metabolism
Rosuvastatin Calcium/*blood
Administration, Oral ; Adult ; Female ; HEK293 Cells ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacokinetics ; Liver-Specific Organic Anion Transporter 1/genetics ; Male ; Middle Aged ; Models, Biological ; Pharmacogenomic Variants ; Polymorphism, Single Nucleotide ; Rosuvastatin Calcium/administration & dosage ; Rosuvastatin Calcium/pharmacokinetics ; Young Adult
Czasopismo naukowe
Tytuł :
Pharmacokinetic Interaction Between Telmisartan and Rosuvastatin/Ezetimibe After Multiple Oral Administration in Healthy Subjects.
Autorzy :
Kim CH; Department of Urology, Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea.
Kang SI; Clinical Development, Navipharm Co., Ltd., Suwon, South Korea.
Shin D; Department of Pharmacology, Gachon University College of Medicine, Incheon, South Korea. .; Clinical Trials Center, Gachon University Gil Medical Center, Incheon, South Korea. .
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Źródło :
Advances in therapy [Adv Ther] 2021 Feb; Vol. 38 (2), pp. 1094-1105. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Rosuvastatin Calcium*
Administration, Oral ; Area Under Curve ; Cross-Over Studies ; Drug Interactions ; Ezetimibe ; Healthy Volunteers ; Humans ; Male ; Telmisartan
Czasopismo naukowe
Tytuł :
Oral Bioavailability Improvement of Tailored Rosuvastatin Loaded Niosomal Nanocarriers to Manage Ischemic Heart Disease: Optimization, Ex Vivo and In Vivo Studies.
Autorzy :
Liu Q; Medical College, Pingdingshan University, Chongwen Road, Pingdingshan City, 467000, Henan Province, China.
Xu J; Nursing College, Hubei Polytechnic Institute, Yuquan Road, Xiaogan City, 432000, Hubei Province, China.
Liao K; Cardiovascular Medicine Department, Affiliated Hospital of Xiangnan University, Renminxi Road, Chenzhou City, 423000, Hunan Province, China. .
Tang N; Cardiovascular Medicine Department, Affiliated Hospital of Xiangnan University, Renminxi Road, Chenzhou City, 423000, Hunan Province, China. .
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Źródło :
AAPS PharmSciTech [AAPS PharmSciTech] 2021 Jan 27; Vol. 22 (2), pp. 58. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Myocardial Ischemia/*drug therapy
Rosuvastatin Calcium/*administration & dosage
Animals ; Biological Availability ; Drug Carriers ; Liposomes ; Male ; Rats ; Rats, Wistar ; Rosuvastatin Calcium/pharmacokinetics
Czasopismo naukowe
Tytuł :
Preclinical cardiac organ damage during statin treatment in patients with inflammatory joint diseases: the RORA-AS statin intervention study.
Autorzy :
Os HA; Department of Clinical Science, University of Bergen, Bergen.
Rollefstad S; Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo.
Gerdts E; Department of Clinical Science, University of Bergen, Bergen.
Kringeland E; Department of Clinical Science, University of Bergen, Bergen.
Ikdahl E; Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo.
Semb AG; Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo.
Midtbø H; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Dec 01; Vol. 59 (12), pp. 3700-3708.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthritis/*complications
Heart/*drug effects
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Rosuvastatin Calcium/*therapeutic use
Aged ; Echocardiography ; Female ; Heart/diagnostic imaging ; Heart Diseases/diagnostic imaging ; Heart Diseases/etiology ; Heart Diseases/prevention & control ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Male ; Middle Aged ; Rosuvastatin Calcium/pharmacology
Czasopismo naukowe
Tytuł :
Rosuvastatin inhibit spheroid formation and epithelial-mesenchymal transition (EMT) in prostate cancer PC-3 cell line.
Autorzy :
Deezagi A; Department of Molecular Medicine, National Institute of Genetic Engineering and Biotechnology, Km. 17, Karaj-Tehran freeway, Pajouhesh Blvd., P.O.Box 14155-6343, Tehran, Iran. .
Safari N; Department of Molecular Medicine, National Institute of Genetic Engineering and Biotechnology, Km. 17, Karaj-Tehran freeway, Pajouhesh Blvd., P.O.Box 14155-6343, Tehran, Iran.
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Źródło :
Molecular biology reports [Mol Biol Rep] 2020 Nov; Vol. 47 (11), pp. 8727-8737. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Cell Proliferation/*drug effects
Epithelial-Mesenchymal Transition/*drug effects
Prostatic Neoplasms/*pathology
Rosuvastatin Calcium/*pharmacology
Spheroids, Cellular/*drug effects
Antigens, CD/metabolism ; Antineoplastic Agents/administration & dosage ; Cadherins/metabolism ; Drug Repositioning ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Male ; PC-3 Cells ; Prostatic Neoplasms/drug therapy ; Rosuvastatin Calcium/administration & dosage ; Vimentin/metabolism ; Zinc Finger E-box-Binding Homeobox 1/metabolism
Czasopismo naukowe
Tytuł :
Comparison of High-Dose Rosuvastatin Versus Low-Dose Rosuvastatin Plus Ezetimibe on Carotid Atherosclerotic Plaque Inflammation in Patients with Acute Coronary Syndrome.
Autorzy :
Oh M; Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Kim H; Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Shin EW; Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Sung C; Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Kim DH; Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Moon DH; Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Kim N; Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Eo JS; Department of Nuclear Medicine, Korea University Guro Hospital, Seoul, South Korea.
Kim JW; Cardiovascular Center, Korea University Guro Hospital, Seoul, South Korea.
Lee CW; Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. .; Division of Cardiology, Heart Institute, Asan Medical Center, University of Ulsan, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea. .
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Źródło :
Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2020 Dec; Vol. 13 (6), pp. 900-907. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Plaque, Atherosclerotic*
Acute Coronary Syndrome/*drug therapy
Anti-Inflammatory Agents/*administration & dosage
Anticholesteremic Agents/*administration & dosage
Carotid Artery Diseases/*drug therapy
Ezetimibe/*administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Rosuvastatin Calcium/*administration & dosage
Acute Coronary Syndrome/diagnostic imaging ; Aged ; Anti-Inflammatory Agents/adverse effects ; Anticholesteremic Agents/adverse effects ; Carotid Artery Diseases/diagnostic imaging ; Drug Combinations ; Ezetimibe/adverse effects ; Female ; Fluorodeoxyglucose F18/administration & dosage ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Male ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Prospective Studies ; Radiopharmaceuticals/administration & dosage ; Rosuvastatin Calcium/adverse effects ; Seoul ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents.
Autorzy :
Kumar JS; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Thirupataiah B; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Medishetti R; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Ray A; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
Bele SD; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
Hossain KA; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
Reddy GS; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Edwin RK; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
Joseph A; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Kumar N; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Shenoy GG; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Rao CM; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
Pal M; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2020 Sep 01; Vol. 201, pp. 112335. Date of Electronic Publication: 2020 Jun 14.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Benzofurans/*pharmacology
Isocoumarins/*pharmacology
Rosuvastatin Calcium/*analogs & derivatives
Rosuvastatin Calcium/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/toxicity ; Benzofurans/chemical synthesis ; Benzofurans/toxicity ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Embryo, Nonmammalian/drug effects ; Humans ; Isocoumarins/chemical synthesis ; Isocoumarins/toxicity ; Molecular Structure ; Rosuvastatin Calcium/toxicity ; Structure-Activity Relationship ; Ultrasonic Waves ; Zebrafish
Czasopismo naukowe
Tytuł :
Multiblock modelling on the study of the kinetic degradation of rosuvastatin calcium in the presence of retention time shifts and rank deficiency.
Autorzy :
Pinto L; Department of Fundamental Chemistry, Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil. Electronic address: .
Jardim ICSF; Department of Analytical Chemistry, Institute of Chemistry, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Rutledge DN; Université Paris-Saclay, INRAE, AgroParisTech, UMR SayFood, 75005, Paris, France; National Wine and Grape Industry Centre, Charles Sturt University, Wagga Wagga, Australia.
Breitkreitz MC; Department of Analytical Chemistry, Institute of Chemistry, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
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Źródło :
Analytica chimica acta [Anal Chim Acta] 2020 Oct 09; Vol. 1133, pp. 77-87. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, Liquid*
Rosuvastatin Calcium*
Chromatography, High Pressure Liquid ; Drug Stability ; Kinetics ; Models, Chemical
Czasopismo naukowe
Tytuł :
Enhanced in vivo targeting of estrogen receptor alpha signaling in murine mammary adenocarcinoma by nilotinib/rosuvastatin novel combination.
Autorzy :
Goda AE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt. Electronic address: .
Elsisi AE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Sokkar SS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Abdelrazik NM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Oct 01; Vol. 404, pp. 115185. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*veterinary
Estrogen Receptor alpha/*antagonists & inhibitors
Mammary Neoplasms, Animal/*drug therapy
Pyrimidines/*therapeutic use
Rosuvastatin Calcium/*therapeutic use
Adenocarcinoma/drug therapy ; Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/therapeutic use ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Mammary Neoplasms, Experimental/drug therapy ; Mice ; Pyrimidines/administration & dosage ; Rosuvastatin Calcium/administration & dosage
SCR Disease Name :
Adenocarcinoid tumor
Czasopismo naukowe
Tytuł :
Efficacy and safety of co-administered telmisartan/amlodipine and rosuvastatin in subjects with hypertension and dyslipidemia.
Autorzy :
Jin X; Department of Cardiology, Dong-A University Hospital, Busan, Korea.
Kim MH; Department of Cardiology, Dong-A University Hospital, Busan, Korea.
Han KH; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, Seoul, Korea.
Hong SJ; Division of Cardiology, Department of Cardiovascular Center, Korea University Anam Hospital, Seoul, Korea.
Ahn JC; Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea.
Sung JH; Department of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Cho JM; Division of Cardiology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
Lee HC; Division of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Busan, Korea.
Choi SY; Department of Cardiology, Ajou University School of Medicine, Suwon, Korea.
Lee K; Division of Cardiology, Gachon University Gil Medical Center, Incheon, Korea.
Kim WS; Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.
Rhee MY; Cardiovascular Center, Dongguk University Ilsan Hospital, Goyang, Korea.
Kim JH; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.
Hong SP; Division of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea.
Yoo BS; Division of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
Cho EJ; Division of Cardiology, Department of Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Lee JH; Department of Cardiology in Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.
Kim PJ; Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Park CG; Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
Hyon MS; Division of Cardiology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea.
Shin JH; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Lee SH; Division of Cardiology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.
Sung KC; Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, Seoul, Korea.
Hwang J; Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, Korea.
Kwon K; Department of Cardiology, Ewha Womans University College of Medicine, Seoul, Korea.
Chae IH; Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Seo JS; Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Kim H; Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.
Lee H; Yuhan Research Institute, Yuhan Corporation, Yongin, Korea.
Cho Y; Yuhan Research Institute, Yuhan Corporation, Yongin, Korea.
Kim HS; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
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Źródło :
Journal of clinical hypertension (Greenwich, Conn.) [J Clin Hypertens (Greenwich)] 2020 Oct; Vol. 22 (10), pp. 1835-1845. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Dyslipidemias*/drug therapy
Hypertension*/drug therapy
Amlodipine/*administration & dosage
Rosuvastatin Calcium/*administration & dosage
Telmisartan/*administration & dosage
Aged ; Amlodipine/therapeutic use ; Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Double-Blind Method ; Drug Combinations ; Drug Therapy, Combination ; Female ; Humans ; Male ; Middle Aged ; Rosuvastatin Calcium/therapeutic use ; Telmisartan/therapeutic use
Czasopismo naukowe
Tytuł :
Effects of High-Dose Rosuvastatin on Ventricular Remodelling and Cardiac Function in ST-Segment Elevation Myocardial Infarction.
Autorzy :
Luo R; Department of Cardiology, Qingpu Medical Center, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Sun X; Department of Cardiology, Qingpu Medical Center, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Shen F; Department of Cardiology, Qingpu Medical Center, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Hong B; Department of Cardiology, Qingpu Medical Center, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Wang Z; Department of Cardiology, Qingpu Medical Center, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2020 Sep 23; Vol. 14, pp. 3891-3898. Date of Electronic Publication: 2020 Sep 23 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Rosuvastatin Calcium/*pharmacology
ST Elevation Myocardial Infarction/*drug therapy
Ventricular Remodeling/*drug effects
Dose-Response Relationship, Drug ; Echocardiography ; Female ; Humans ; Male ; Middle Aged ; Rosuvastatin Calcium/administration & dosage ; ST Elevation Myocardial Infarction/diagnostic imaging
Czasopismo naukowe
Tytuł :
Comparison of the preventive efficacy of rosuvastatin versus atorvastatin in post-contrast acute kidney injury in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention.
Autorzy :
Dai Y; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China.
Huang J; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China.
Zeng L; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
Huang Z; Shantou University Medical College, Shantou, 515041, China.
Duan C; Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Shao S; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China.
Chen H; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China.
Xue L; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China.
Chen J; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China.
Tan N; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
He P; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
Liu Y; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China. Electronic address: .
Yu D; Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Aug; Vol. 128, pp. 110336. Date of Electronic Publication: 2020 Jun 07.
Typ publikacji :
Comparative Study; Journal Article; Observational Study
MeSH Terms :
Percutaneous Coronary Intervention*/adverse effects
Percutaneous Coronary Intervention*/mortality
Acute Kidney Injury/*prevention & control
Atorvastatin/*therapeutic use
Contrast Media/*administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Rosuvastatin Calcium/*therapeutic use
ST Elevation Myocardial Infarction/*therapy
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/mortality ; Aged ; Atorvastatin/adverse effects ; Biomarkers/blood ; Contrast Media/adverse effects ; Creatinine/blood ; Female ; Hospital Mortality ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Male ; Middle Aged ; Risk Factors ; Rosuvastatin Calcium/adverse effects ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/mortality ; Time Factors ; Treatment Outcome ; Up-Regulation
Czasopismo naukowe
Tytuł :
Generic atorvastatin and rosuvastatin in the South Korean market: time of introduction in relation to manufacturer characteristics.
Autorzy :
Son KB; College of Pharmacy, Ewha Womans University , Seoul, South Korea.
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Źródło :
Expert review of pharmacoeconomics & outcomes research [Expert Rev Pharmacoecon Outcomes Res] 2020 Oct; Vol. 20 (5), pp. 541-548. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Atorvastatin/*economics
Drug Industry/*economics
Drugs, Generic/*economics
Rosuvastatin Calcium/*economics
Anticholesteremic Agents/administration & dosage ; Anticholesteremic Agents/economics ; Atorvastatin/administration & dosage ; Drug Costs ; Economic Competition ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/economics ; Republic of Korea ; Rosuvastatin Calcium/administration & dosage ; Time Factors
Czasopismo naukowe
Tytuł :
Combinational Use of Antiplatelet Medication Sarpogrelate with Therapeutic Drug Rosuvastatin in Treating High-Cholesterol Diet-Induced Chronic Kidney Disease in ApoE-Deficient Mice.
Autorzy :
Xu J; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Pei Z; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Yu M; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Li X; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Wang L; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Lin Y; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Chen X; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Liu X; Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Sep 26; Vol. 2020, pp. 1809326. Date of Electronic Publication: 2020 Sep 26 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Apolipoproteins E/*deficiency
Platelet Aggregation Inhibitors/*therapeutic use
Renal Insufficiency, Chronic/*drug therapy
Rosuvastatin Calcium/*therapeutic use
Succinates/*therapeutic use
Animals ; Cholesterol, Dietary ; Diet, High-Fat ; Drug Therapy, Combination ; Gene Expression Regulation/drug effects ; Homeostasis/drug effects ; Inflammation/genetics ; Kidney Cortex/drug effects ; Kidney Cortex/pathology ; Lipid Metabolism/drug effects ; Male ; Mice, Knockout ; Platelet Aggregation Inhibitors/pharmacology ; Renal Insufficiency, Chronic/genetics ; Renal Insufficiency, Chronic/pathology ; Rosuvastatin Calcium/pharmacology ; Succinates/pharmacology
Czasopismo naukowe
Tytuł :
Effects of exercise training and statin on hemodynamic, biochemical, inflammatory and immune profile of people living with HIV: a randomized, double-blind, placebo-controlled trial.
Autorzy :
Zanetti HR; IMEPAC University Center, Araguari, Brazil - .
Mendes EL; Federal University of Triângulo Mineiro, Uberaba, Brazil.
Gonçalves A; IMEPAC University Center, Araguari, Brazil.
Lopes LT; Brazil University, Fernandópolis, Brazil.
Roever L; Federal University of Uberlândia, Uberlândia, Brazil.
Silva-Vergara ML; Federal University of Triângulo Mineiro, Uberaba, Brazil.
Neves FF; Federal University of Triângulo Mineiro, Uberaba, Brazil.
Resende ES; Federal University of Uberlândia, Uberlândia, Brazil.
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Źródło :
The Journal of sports medicine and physical fitness [J Sports Med Phys Fitness] 2020 Sep; Vol. 60 (9), pp. 1275-1282.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Exercise/*physiology
HIV Infections/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Rosuvastatin Calcium/*administration & dosage
Adult ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Blood Pressure/drug effects ; Creatine Kinase/blood ; Double-Blind Method ; Female ; Glycated Hemoglobin A/metabolism ; HIV Infections/blood ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Male ; Middle Aged ; Rosuvastatin Calcium/adverse effects
Czasopismo naukowe

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