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Wyszukujesz frazę ""sars-cov-2"" wg kryterium: Temat


Tytuł:
SARS-CoV-2 Omicron BA.1 Variant Infection of Human Colon Epithelial Cells.
Autorzy:
Antia A; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Alvarado DM; Inflammatory Bowel Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Zeng Q; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Casorla-Perez LA; Inflammatory Bowel Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Davis DL; Inflammatory Bowel Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Sonnek NM; Inflammatory Bowel Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Ciorba MA; Inflammatory Bowel Diseases Center, Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
Ding S; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
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Źródło:
Viruses [Viruses] 2024 Apr 19; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/physiology
SARS-CoV-2*/pathogenicity
Colon*/virology
COVID-19*/virology
Epithelial Cells*/virology
Spike Glycoprotein, Coronavirus*/metabolism
Spike Glycoprotein, Coronavirus*/genetics
Humans ; Virus Replication ; Interferon Lambda
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
1-L Transcription of SARS-CoV-2 Spike Protein S1 Subunit.
Autorzy:
Nahalka J; Institute of Chemistry, Centre for Glycomics, Slovak Academy of Sciences, Dubravska Cesta 9, SK-84538 Bratislava, Slovakia.; Institute of Chemistry, Centre of Excellence for White-Green Biotechnology, Slovak Academy of Sciences, Trieda Andreja Hlinku 2, SK-94976 Nitra, Slovakia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 18; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 18.
Typ publikacji:
Journal Article
MeSH Terms:
Spike Glycoprotein, Coronavirus*/genetics
Spike Glycoprotein, Coronavirus*/metabolism
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*/virology
COVID-19*/metabolism
COVID-19*/genetics
Humans ; Transcription, Genetic ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Computational Biology/methods ; Transcriptome
Czasopismo naukowe
Tytuł:
Exploring Binding Pockets in the Conformational States of the SARS-CoV-2 Spike Trimers for the Screening of Allosteric Inhibitors Using Molecular Simulations and Ensemble-Based Ligand Docking.
Autorzy:
Gupta G; Keck Center for Science and Engineering, Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.
Verkhivker G; Keck Center for Science and Engineering, Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, CA 92618, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 01; Vol. 25 (9). Date of Electronic Publication: 2024 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Spike Glycoprotein, Coronavirus*/chemistry
Spike Glycoprotein, Coronavirus*/metabolism
Spike Glycoprotein, Coronavirus*/antagonists & inhibitors
Molecular Docking Simulation*
Allosteric Site*
SARS-CoV-2*/drug effects
SARS-CoV-2*/metabolism
Molecular Dynamics Simulation*
Protein Binding*
Allosteric Regulation ; Ligands ; Humans ; Binding Sites ; Protein Conformation ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Antiviral Agents/metabolism ; Protein Multimerization ; Machine Learning
Czasopismo naukowe
Tytuł:
Thapsigargin and Tunicamycin Block SARS-CoV-2 Entry into Host Cells via Differential Modulation of Unfolded Protein Response (UPR), AKT Signaling, and Apoptosis.
Autorzy:
Al Otaibi A; King Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Ahsa 31982, Saudi Arabia.; Biomedical Research Department, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Al Ahsa 36428, Saudi Arabia.; King Abdulaziz Hospital, Ministry of National Guard-Health Affairs (MNG-HA), Al Ahsa 36428, Saudi Arabia.
Al Shaikh Mubarak S; King Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Ahsa 31982, Saudi Arabia.; Biomedical Research Department, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Al Ahsa 36428, Saudi Arabia.; King Abdulaziz Hospital, Ministry of National Guard-Health Affairs (MNG-HA), Al Ahsa 36428, Saudi Arabia.
Al Hejji F; King Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Ahsa 31982, Saudi Arabia.
Almasaud A; Vaccine Development Unit, Department of Infectious Disease Research, King Abdullah International Medical Research Center, Riyadh 11481, Saudi Arabia.
Al Jami H; Vaccine Development Unit, Department of Infectious Disease Research, King Abdullah International Medical Research Center, Riyadh 11481, Saudi Arabia.
Iqbal J; King Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Ahsa 31982, Saudi Arabia.; Biomedical Research Department, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Al Ahsa 36428, Saudi Arabia.; King Abdulaziz Hospital, Ministry of National Guard-Health Affairs (MNG-HA), Al Ahsa 36428, Saudi Arabia.
Al Qarni A; King Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Ahsa 31982, Saudi Arabia.; Biomedical Research Department, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Al Ahsa 36428, Saudi Arabia.; King Abdulaziz Hospital, Ministry of National Guard-Health Affairs (MNG-HA), Al Ahsa 36428, Saudi Arabia.
Harbi NKA; Vaccine Development Unit, Department of Infectious Disease Research, King Abdullah International Medical Research Center, Riyadh 11481, Saudi Arabia.
Bakillah A; King Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Ahsa 31982, Saudi Arabia.; Biomedical Research Department, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Al Ahsa 36428, Saudi Arabia.; King Abdulaziz Hospital, Ministry of National Guard-Health Affairs (MNG-HA), Al Ahsa 36428, Saudi Arabia.
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Źródło:
Cells [Cells] 2024 Apr 30; Vol. 13 (9). Date of Electronic Publication: 2024 Apr 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Thapsigargin*/pharmacology
Unfolded Protein Response*/drug effects
Tunicamycin*/pharmacology
Apoptosis*/drug effects
SARS-CoV-2*/drug effects
SARS-CoV-2*/physiology
Endoplasmic Reticulum Chaperone BiP*
Signal Transduction*/drug effects
Proto-Oncogene Proteins c-akt*/metabolism
Endoplasmic Reticulum Stress*/drug effects
Humans ; COVID-19/virology ; COVID-19/metabolism ; Virus Internalization/drug effects
Czasopismo naukowe
Tytuł:
Co-Mutations and Possible Variation Tendency of the Spike RBD and Membrane Protein in SARS-CoV-2 by Machine Learning.
Autorzy:
Ye Q; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.
Wang H; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.
Xu F; School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Zhang S; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.
Zhang S; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.
Yang Z; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.; School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Zhang L; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 25; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
Spike Glycoprotein, Coronavirus*/genetics
Spike Glycoprotein, Coronavirus*/chemistry
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Machine Learning*
COVID-19*/virology
COVID-19*/genetics
Mutation*
Humans ; Viral Matrix Proteins/genetics ; Viral Matrix Proteins/chemistry ; Coronavirus M Proteins/genetics ; Protein Domains/genetics ; Amino Acid Sequence ; Protein Binding
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Estimating SARS-CoV-2 infection probabilities with serological data and a Bayesian mixture model.
Autorzy:
Glemain B; Sorbonne Université, Inserm, Institut Pierre-Louis d'épidémiologie et de santé publique, Paris, France. .; Département de santé publique, Hôpital Saint-Antoine, AP-HP. Sorbonne Université, Paris, France. .
de Lamballerie X; Unité des Virus Émergents, UVE, IRD 190, INSERM 1207, IHU Méditerranée Infection, Aix Marseille Univ, Marseille, France.
Zins M; Paris University, Paris, France.; Université Paris-Saclay, Université de Paris, UVSQ, Inserm UMS 11, Villejuif, France.
Severi G; CESP UMR1018, Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, Villejuif, France.; Department of Statistics, Computer Science and Applications, University of Florence, Florence, Italy.
Touvier M; Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center, University of Paris (CRESS), Bobigny, France.
Deleuze JF; Fondation Jean Dausset-CEPH (Centre d'Etude du Polymorphisme Humain), CEPH-Biobank, Paris, France.
Lapidus N; Sorbonne Université, Inserm, Institut Pierre-Louis d'épidémiologie et de santé publique, Paris, France.; Département de santé publique, Hôpital Saint-Antoine, AP-HP. Sorbonne Université, Paris, France.
Carrat F; Sorbonne Université, Inserm, Institut Pierre-Louis d'épidémiologie et de santé publique, Paris, France.; Département de santé publique, Hôpital Saint-Antoine, AP-HP. Sorbonne Université, Paris, France.
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Corporate Authors:
SAPRIS-SERO study group
Źródło:
Scientific reports [Sci Rep] 2024 Apr 25; Vol. 14 (1), pp. 9503. Date of Electronic Publication: 2024 Apr 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/blood
COVID-19*/diagnosis
COVID-19*/immunology
COVID-19*/virology
Bayes Theorem*
SARS-CoV-2*/immunology
SARS-CoV-2*/isolation & purification
Antibodies, Viral*/blood
Humans ; Middle Aged ; Adult ; France/epidemiology ; Aged ; Probability ; Immunoglobulin G/blood ; Adolescent ; Female ; COVID-19 Serological Testing/methods ; Young Adult ; Male ; Incidence ; Child ; Child, Preschool ; Infant ; Aged, 80 and over
Czasopismo naukowe
Tytuł:
A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein.
Autorzy:
Civit L; Interdisciplinary Nanoscience Center, Aarhus University, DK-8000 Aarhus, Denmark.
Moradzadeh N; Life and Medical Sciences (LIMES), University of Bonn, 53121 Bonn, Germany.
Jonczyk A; Life and Medical Sciences (LIMES), University of Bonn, 53121 Bonn, Germany.
Neckermann P; Institute of Medical Microbiology and Hygiene, Molecular Microbiology (Virology), Regensburg University, 93053 Regensburg, Germany.
Asbach B; Institute of Medical Microbiology and Hygiene, Molecular Microbiology (Virology), Regensburg University, 93053 Regensburg, Germany.
Peterhoff D; Institute of Medical Microbiology and Hygiene, Molecular Microbiology (Virology), Regensburg University, 93053 Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, 93053 Regensburg, Germany.
Wagner R; Institute of Medical Microbiology and Hygiene, Molecular Microbiology (Virology), Regensburg University, 93053 Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, 93053 Regensburg, Germany.
Famulok M; Life and Medical Sciences (LIMES), University of Bonn, 53121 Bonn, Germany.; Center of Aptamer Research & Development, University of Bonn, 53121 Bonn, Germany.
Mayer G; Life and Medical Sciences (LIMES), University of Bonn, 53121 Bonn, Germany.; Center of Aptamer Research & Development, University of Bonn, 53121 Bonn, Germany.
Kjems J; Interdisciplinary Nanoscience Center, Aarhus University, DK-8000 Aarhus, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus, Denmark.
Valero J; Interdisciplinary Nanoscience Center, Aarhus University, DK-8000 Aarhus, Denmark.; Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 24; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Aptamers, Nucleotide*/metabolism
Aptamers, Nucleotide*/chemistry
Spike Glycoprotein, Coronavirus*/metabolism
SARS-CoV-2*/metabolism
SARS-CoV-2*/drug effects
COVID-19*/virology
COVID-19*/metabolism
Protein Binding*
Humans ; Interferometry/methods ; Flow Cytometry/methods
Czasopismo naukowe
Tytuł:
Characterizing Infections in Two Epidemic Waves of SARS-CoV-2 Omicron Variants: A Cohort Study in Guangzhou, China.
Autorzy:
Qu L; School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Xie C; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; School of Basic Medicine and Public Health, Jinan University, Guangzhou 510632, China.
Qiu M; School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Yi L; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Liu Z; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Zou L; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Hu P; Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Jiang H; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; School of Public Health, Southern Medical University, Guangzhou 510515, China.
Lian H; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; School of Public Health, Southern Medical University, Guangzhou 510515, China.
Yang M; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; School of Basic Medicine and Public Health, Jinan University, Guangzhou 510632, China.
Yang H; School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Zeng H; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, China.
Chen H; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; School of Basic Medicine and Public Health, Jinan University, Guangzhou 510632, China.
Zhao J; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.
Xiao J; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.
He J; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Yang Y; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.
Chen L; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.
Li B; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.; Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Sun J; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Lu J; School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.; Guangdong Provincial Institution of Public Health, Guangzhou 511430, China.; Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangdong Provincial Key Laboratory of Pathogen Detection for Emerging Infectious Disease Response, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
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Źródło:
Viruses [Viruses] 2024 Apr 22; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/virology
COVID-19*/immunology
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
SARS-CoV-2*/classification
Antibodies, Neutralizing*/blood
Antibodies, Neutralizing*/immunology
Antibodies, Viral*/blood
Viral Load*
Humans ; China/epidemiology ; Male ; Female ; Adult ; Middle Aged ; Prospective Studies ; Cohort Studies ; Young Adult ; Aged
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Multiple Sclerosis Onset before and after COVID-19 Vaccination: Can HLA Haplotype Be Determinant?
Autorzy:
Bianco A; Division of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
Di Sante G; Department of Medicine and Surgery, Section of Human, Clinical and Forensic Anatomy, University of Perugia, 06123 Perugia, Italy.
Colò F; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
De Arcangelis V; Division of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Cicia A; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
Del Giacomo P; Department of Laboratory and Infectious Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
De Bonis M; Departmental Unit of Molecular and Genomic Diagnostics, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Genomics Core Facility, Gemelli Science and Technology Park (G-STeP), Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Morganti TG; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
Carlomagno V; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
Lucchini M; Division of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
Minucci A; Departmental Unit of Molecular and Genomic Diagnostics, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Genomics Core Facility, Gemelli Science and Technology Park (G-STeP), Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Calabresi P; Division of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
Mirabella M; Division of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Neurosciences, Centro di Ricerca per la Sclerosi Multipla 'Anna Paola Batocchi', Catholic University of Sacred Heart, 00168 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 22; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 22.
Typ publikacji:
Journal Article
MeSH Terms:
HLA-DRB1 Chains*/genetics
COVID-19*/genetics
COVID-19*/prevention & control
COVID-19*/immunology
COVID-19*/epidemiology
Haplotypes*
COVID-19 Vaccines*/adverse effects
COVID-19 Vaccines*/immunology
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Humans ; Female ; Male ; Adult ; Retrospective Studies ; Middle Aged ; Vaccination ; Multiple Sclerosis, Relapsing-Remitting/genetics ; Multiple Sclerosis, Relapsing-Remitting/immunology ; Multiple Sclerosis/genetics ; Genetic Predisposition to Disease
Czasopismo naukowe
Tytuł:
The Recognition Pathway of the SARS-CoV-2 Spike Receptor-Binding Domain to Human Angiotensin-Converting Enzyme 2.
Autorzy:
Peng C; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300350, China.
Lv X; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300350, China.
Zhang Z; Xiongan Institute of Innovation, Xiong'an New Area 070001, China.
Lin J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300350, China.
Li D; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300350, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Apr 19; Vol. 29 (8). Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Spike Glycoprotein, Coronavirus*/metabolism
Spike Glycoprotein, Coronavirus*/chemistry
Spike Glycoprotein, Coronavirus*/genetics
Angiotensin-Converting Enzyme 2*/metabolism
Angiotensin-Converting Enzyme 2*/chemistry
Angiotensin-Converting Enzyme 2*/genetics
SARS-CoV-2*/metabolism
SARS-CoV-2*/genetics
Molecular Dynamics Simulation*
Protein Binding*
Humans ; Binding Sites ; COVID-19/virology ; COVID-19/metabolism ; Protein Domains ; Mutation
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Detection of SARS-CoV-2 Delta Variant (B.1.617.2) in Domestic Dogs and Zoo Tigers in England and Jersey during 2021.
Autorzy:
Seekings AH; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; National Reference Laboratory for SARS-CoV-2 in Animals, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Shipley R; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; National Reference Laboratory for SARS-CoV-2 in Animals, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Byrne AMP; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; Worldwide Influenza Centre, The Francis Crick Institute, Midland Road, London NW1 1AT, UK.
Shukla S; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; National Reference Laboratory for SARS-CoV-2 in Animals, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Golding M; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Amaya-Cuesta J; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Goharriz H; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; National Reference Laboratory for SARS-CoV-2 in Animals, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Vitores AG; Department of Pathology and Animal Sciences, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Lean FZX; Department of Pathology and Animal Sciences, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
James J; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Núñez A; Department of Pathology and Animal Sciences, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Breed A; Government of Jersey, Infrastructure Housing and Environment, Howard Davis Farm, La Route de la Trinité, Trinity, Jersey JE3 5JP, UK.
Frost A; One Health, Animal Health and Welfare Advice Team, Animal and Plant Health Agency, Nobel House, 17 Smith Square, London SW1P 3JR, UK.
Balzer J; Vet Med Labor GmbH, Division of IDEXX Laboratories, Humboldtstraße 2, 70806 Kornwestheim, Germany.
Brown IH; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
Brookes SM; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
McElhinney LM; Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.; National Reference Laboratory for SARS-CoV-2 in Animals, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.
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Źródło:
Viruses [Viruses] 2024 Apr 16; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Case Reports
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/isolation & purification
SARS-CoV-2*/classification
COVID-19*/transmission
COVID-19*/epidemiology
COVID-19*/veterinary
COVID-19*/virology
Tigers*/virology
Animals, Zoo*/virology
Animals ; Dogs ; Cats ; England/epidemiology ; Humans ; Phylogeny ; Dog Diseases/virology ; Dog Diseases/epidemiology ; Dog Diseases/transmission ; Zoonoses/virology ; Zoonoses/transmission ; Zoonoses/epidemiology
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Natural Killer Cells Do Not Attenuate a Mouse-Adapted SARS-CoV-2-Induced Disease in Rag2 Mice.
Autorzy:
Ellsworth CR; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Wang C; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Katz AR; Departments of Medicine and Pediatrics, Center for Translational Research in Infection and Inflammation, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Chen Z; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Islamuddin M; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Yang H; Departments of Medicine and Pediatrics, Center for Translational Research in Infection and Inflammation, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Department of Pulmonary Critical Care and Environmental Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Scheuermann SE; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.
Goff KA; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.
Maness NJ; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Blair RV; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.
Kolls JK; Departments of Medicine and Pediatrics, Center for Translational Research in Infection and Inflammation, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Department of Pulmonary Critical Care and Environmental Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Qin X; Division of Comparative Pathology, Tulane National Primate Research Center, Health Sciences Campus, 18703 Three Rivers Road, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
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Źródło:
Viruses [Viruses] 2024 Apr 15; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Killer Cells, Natural*/immunology
COVID-19*/immunology
COVID-19*/virology
SARS-CoV-2*/immunology
SARS-CoV-2*/pathogenicity
Disease Models, Animal*
Mice, Inbred C57BL*
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/deficiency
Animals ; Mice ; Mice, Knockout ; Humans ; Lung/pathology ; Lung/virology ; Lung/immunology ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; B-Lymphocytes/immunology ; Female ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł:
Clinical Evaluation of the BIOFIRE SPOTFIRE Respiratory Panel.
Autorzy:
Chan WS; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Ho CW; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Chan TC; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Hung J; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
To MY; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Leung SM; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Lai KC; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Wong CY; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Leung CP; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Au CH; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Wan TS; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Zee JS; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Ma ES; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
Tang BS; Department of Pathology, Hong Kong Sanatorium & Hospital, Hong Kong SAR, China.
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Źródło:
Viruses [Viruses] 2024 Apr 13; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/diagnosis
COVID-19*/virology
Respiratory Tract Infections*/virology
Respiratory Tract Infections*/diagnosis
SARS-CoV-2*/genetics
SARS-CoV-2*/isolation & purification
Humans ; Hong Kong ; Sensitivity and Specificity ; Molecular Diagnostic Techniques/methods ; COVID-19 Nucleic Acid Testing/methods
Czasopismo naukowe
Tytuł:
Ensemble-Based Mutational Profiling and Network Analysis of the SARS-CoV-2 Spike Omicron XBB Lineages for Interactions with the ACE2 Receptor and Antibodies: Cooperation of Binding Hotspots in Mediating Epistatic Couplings Underlies Binding Mechanism and Immune Escape.
Autorzy:
Raisinghani N; Keck Center for Science and Engineering, Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.
Alshahrani M; Keck Center for Science and Engineering, Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.
Gupta G; Keck Center for Science and Engineering, Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.
Verkhivker G; Keck Center for Science and Engineering, Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA.; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, CA 92618, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 12; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 12.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2*/metabolism
Angiotensin-Converting Enzyme 2*/genetics
Angiotensin-Converting Enzyme 2*/chemistry
COVID-19*/virology
COVID-19*/genetics
COVID-19*/immunology
Immune Evasion*/genetics
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
SARS-CoV-2*/metabolism
Spike Glycoprotein, Coronavirus*/genetics
Spike Glycoprotein, Coronavirus*/immunology
Spike Glycoprotein, Coronavirus*/metabolism
Spike Glycoprotein, Coronavirus*/chemistry
Humans ; Antibodies, Viral/immunology ; Antibodies, Viral/metabolism ; Binding Sites ; Epistasis, Genetic ; Evolution, Molecular ; Molecular Dynamics Simulation ; Mutation ; Protein Binding
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Measles Virus-Based Vaccine Expressing Membrane-Anchored Spike of SARS-CoV-2 Inducing Efficacious Systemic and Mucosal Humoral Immunity in Hamsters.
Autorzy:
Yang ZH; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Song YL; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Pei J; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Li SZ; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Liu RL; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Xiong Y; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Wu J; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Liu YL; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Fan HF; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Wu JH; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Wang ZJ; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Guo J; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Meng SL; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Chen XQ; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Lu J; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
Shen S; Wuhan Institute of Biological Products Co. Ltd., Wuhan 430207, China.
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Źródło:
Viruses [Viruses] 2024 Apr 03; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Spike Glycoprotein, Coronavirus*/immunology
Spike Glycoprotein, Coronavirus*/genetics
SARS-CoV-2*/immunology
SARS-CoV-2*/genetics
Antibodies, Viral*/blood
Antibodies, Viral*/immunology
Immunity, Mucosal*
Antibodies, Neutralizing*/blood
Antibodies, Neutralizing*/immunology
Immunity, Humoral*
COVID-19*/prevention & control
COVID-19*/immunology
COVID-19 Vaccines*/immunology
COVID-19 Vaccines*/administration & dosage
Measles virus*/immunology
Measles virus*/genetics
Immunoglobulin A*/blood
Animals ; Cricetinae ; Humans ; Administration, Intranasal ; Mesocricetus ; Female
Czasopismo naukowe
Tytuł:
Establishment of the First National Standard for Neutralizing Antibodies against SARS-CoV-2 XBB Variants.
Autorzy:
Zhang X; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Guan L; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Li N; Beijing Minhai Biotechnology Co., Ltd., Beijing 102600, China.
Wang Y; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Li L; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Liu M; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
He Q; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Lu J; Yunnan Institute for Food and Drug Control, Kunming 650106, China.
Zeng H; Yunnan Institute for Food and Drug Control, Kunming 650106, China.
Yu S; Jiangsu Institute for Food and Drug Control, Nanjing 210019, China.
Guo X; Hualan Biological Engineering Chongqing Co., Ltd., Chongqing 408107, China.
Gong J; China Resources Boya Bio-Pharmaceutical Group Co., Ltd., Fuzhou 344000, China.
Li J; Beijing Kexing Zhongwei Biotechnology Co., Ltd., Beijing 102600, China.
Gao F; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Wu X; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Chen S; Drug and Vaccine Research Center, Guangzhou National Laboratory, Guangzhou 510535, China.
Wang Q; Drug and Vaccine Research Center, Guangzhou National Laboratory, Guangzhou 510535, China.
Wang Z; Drug and Vaccine Research Center, Guangzhou National Laboratory, Guangzhou 510535, China.
Huang W; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Mao Q; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Liang Z; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
Xu M; Institute of Biological Products, National Institutes for Food and Drug Control, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, State Key Laboratory of Drug Regulatory Science, Beijing 102629, China.
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Źródło:
Viruses [Viruses] 2024 Apr 01; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/immunology
SARS-CoV-2*/genetics
Antibodies, Viral*/immunology
Antibodies, Viral*/blood
Antibodies, Neutralizing*/immunology
Antibodies, Neutralizing*/blood
COVID-19*/immunology
COVID-19*/virology
Neutralization Tests*
Humans ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/genetics ; COVID-19 Vaccines/immunology ; China ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials.
Autorzy:
Hedskog C; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Spinner CD; TUM School of Medicine and Health, Department of Clinical Medicine-Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, 81675 Munich, Germany.
Protzer U; German Center for Infection Research (DZIF), Munich Partner Site, 81675 Munich, Germany.; Institute of Virology, Technical University of Munich School of Medicine, 81675 Munich, Germany.; Institute of Virology, Helmholtz Munich, 85764 Munich, Germany.
Hoffmann D; German Center for Infection Research (DZIF), Munich Partner Site, 81675 Munich, Germany.; Institute of Virology, Technical University of Munich School of Medicine, 81675 Munich, Germany.
Ko C; Institute of Virology, Technical University of Munich School of Medicine, 81675 Munich, Germany.; Institute of Virology, Helmholtz Munich, 85764 Munich, Germany.; Infectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea.
Gottlieb RL; Center for Advanced Heart and Lung Disease, Department of Internal Medicine, Baylor University Medical Center, Dallas, TX 75246, USA.; Baylor Scott & White Research Institute, Dallas, TX 75246, USA.; Department of Internal Medicine, Texas A&M Health Science Center, Dallas, TX 75246, USA.; Department of Internal Medicine, Burnett School of Medicine at TCU, Fort Worth, TX 76109, USA.
Askar M; Center for Advanced Heart and Lung Disease, Department of Internal Medicine, Baylor University Medical Center, Dallas, TX 75246, USA.; QU Health and Department of Immunology, College of Medicine, Qatar University, Doha P.O. Box 2713, Qatar.
Roestenberg M; Leiden University Medical Center for Infectious Diseases (LUCID), 2333 ZA Leiden, The Netherlands.
de Vries JJC; Leiden University Medical Center for Infectious Diseases (LUCID), 2333 ZA Leiden, The Netherlands.
Carbo EC; Leiden University Medical Center for Infectious Diseases (LUCID), 2333 ZA Leiden, The Netherlands.
Martin R; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Li J; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Han D; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Rodriguez L; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Parvangada A; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Perry JK; Gilead Sciences, Inc., Foster City, CA 94404, USA.
Ferrer R; Vall d'Hebron Hospital Universitari, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Medicine Department, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Antón A; Vall d'Hebron Hospital Universitari, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Medicine Department, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Andrés C; Vall d'Hebron Hospital Universitari, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Medicine Department, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Casares V; Vall d'Hebron Hospital Universitari, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Medicine Department, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Günthard HF; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, 8057 Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, 8057 Zurich, Switzerland.
Huber M; Institute of Medical Virology, University of Zurich, 8057 Zurich, Switzerland.
McComsey GA; Department of Medicine, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH 44106, USA.
Sadri N; Department of Medicine, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH 44106, USA.
Aberg JA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
van Bakel H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Porter DP; Gilead Sciences, Inc., Foster City, CA 94404, USA.
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Źródło:
Viruses [Viruses] 2024 Mar 31; Vol. 16 (4). Date of Electronic Publication: 2024 Mar 31.
Typ publikacji:
Journal Article; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't
MeSH Terms:
Alanine*/*analogs & derivatives
Adenosine Monophosphate*/*analogs & derivatives
Alanine*/therapeutic use
Alanine*/pharmacology
Adenosine Monophosphate*/pharmacology
Adenosine Monophosphate*/therapeutic use
SARS-CoV-2*/drug effects
SARS-CoV-2*/genetics
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19 Drug Treatment*
Drug Resistance, Viral*
Viral Load*/drug effects
COVID-19*/virology
Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Severity of Illness Index
Czasopismo naukowe
Tytuł:
Development of a Mouse-Adapted Reporter SARS-CoV-2 as a Tool for Two-Photon In Vivo Imaging.
Autorzy:
Ueki H; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.
Kiso M; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.
Furusawa Y; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.
Iida S; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Yamayoshi S; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.
Nakajima N; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Imai M; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.
Suzuki T; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Kawaoka Y; Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.; Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.; Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53711, USA.
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Źródło:
Viruses [Viruses] 2024 Mar 29; Vol. 16 (4). Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/pathogenicity
SARS-CoV-2*/physiology
COVID-19*/virology
Mice, Inbred C57BL*
Lung*/virology
Lung*/pathology
Lung*/diagnostic imaging
Disease Models, Animal*
Animals ; Mice ; Humans ; Genes, Reporter ; Virus Replication
Czasopismo naukowe
Tytuł:
Effects of Strain Differences, Humidity Changes, and Saliva Contamination on the Inactivation of SARS-CoV-2 by Ion Irradiation.
Autorzy:
Ahmad Wadi AFA; Department of Microbiology, Faculty of Medicine, Shimane University, 89-1 Enya, Izumo 693-8504, Shimane, Japan.; Faculty of Medicine, University of Muslim Indonesia, Makassar 9023, South Sulawesi, Indonesia.
Onomura D; Division of Virology, Department of Infection and Immunity, Faculty of Medicine, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Funamori H; Sharp Corporation, Yao 581-8585, Osaka, Japan.
Khatun MM; Department of Microbiology, Faculty of Medicine, Shimane University, 89-1 Enya, Izumo 693-8504, Shimane, Japan.
Okada S; Department of Microbiology, Faculty of Medicine, Shimane University, 89-1 Enya, Izumo 693-8504, Shimane, Japan.
Iizasa H; Department of Microbiology, Faculty of Medicine, Shimane University, 89-1 Enya, Izumo 693-8504, Shimane, Japan.
Yoshiyama H; Department of Microbiology, Faculty of Medicine, Shimane University, 89-1 Enya, Izumo 693-8504, Shimane, Japan.
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Źródło:
Viruses [Viruses] 2024 Mar 28; Vol. 16 (4). Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/radiation effects
SARS-CoV-2*/physiology
Saliva*/virology
Virus Inactivation*/radiation effects
Humidity*
COVID-19*/virology
COVID-19*/prevention & control
Humans ; Ions ; Animals ; Vero Cells ; Chlorocebus aethiops
Czasopismo naukowe

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