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Tytuł:
Using In Silico Bioinformatics Algorithms for the Accurate Prediction of the Impact of Spike Protein Mutations on the Pathogenicity, Stability, and Functionality of the SARS-CoV-2 Virus and Analysis of Potential Therapeutic Targets.
Autorzy:
Alizadehmohajer N; Department of Medical Biotechnology and Translational Medicine, University of Milan, 20133, Milan, Italy.
Zahedifar S; Department of Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Sohrabi E; Department of Medical Genetics and Molecular Biology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Shaddel Basir S; Department of Microbiology, Faculty of New Sciences and Technologies Branch, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Nourigheimasi S; Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Falak R; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Nedaeinia R; Pediatric Inherited Diseases Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
A Ferns G; Division of Medical Education, Brighton and Sussex Medical School, Falmer, Brighton, BN1 9PH, Sussex, UK.
Emami Nejad A; Department of Biology, Payame Noor University (PNU), P.O.Box 19395-3697, Tehran, Iran. Emami_.
Manian M; Department of Medical Laboratory Science, Faculty of Medical Science, Kermanshah Branch, Imam Khomeini Campus, Islamic Azad University, Farhikhtegan Bld., Shahid J'afari St., 6718997551, Kermanshah, Iran. .; Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. .
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Źródło:
Biochemical genetics [Biochem Genet] 2023 Apr; Vol. 61 (2), pp. 778-808. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*/genetics
Humans ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Molecular Docking Simulation ; Virulence ; Mutation ; Protein Binding
Czasopismo naukowe
Szczegóły
Tytuł:
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Autorzy:
Zhou P; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Song G; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Liu H; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Yuan M; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
He WT; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Zhu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Tse LV; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Martinez DR; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Schäfer A; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Anzanello F; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Yong P; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Peng L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Dueker K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Musharrafieh R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Callaghan S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Capozzola T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Limbo O; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
Parren M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Garcia E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Rawlings SA; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
Smith DM; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
Nemazee D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Jardine JG; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
Safonova Y; Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA.
Briney B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
Rogers TF; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
Wilson IA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: .
Baric RS; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Departments of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: .
Gralinski LE; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: .
Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA. Electronic address: .
Andrabi R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: .
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Źródło:
Immunity [Immunity] 2023 Mar 14; Vol. 56 (3), pp. 669-686.e7. Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
SARS-CoV-2*
COVID-19*
Humans ; Broadly Neutralizing Antibodies ; Antibodies, Neutralizing ; Antibodies, Viral
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Hybridization Chain Reaction Lateral Flow Assays for Amplified Instrument-Free At-Home SARS-CoV-2 Testing.
Autorzy:
Schulte SJ; Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States.
Huang J; Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States.
Pierce NA; Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States.; Division of Engineering & Applied Science, California Institute of Technology, Pasadena, California 91125, United States.
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Źródło:
ACS infectious diseases [ACS Infect Dis] 2023 Mar 10; Vol. 9 (3), pp. 450-458. Date of Electronic Publication: 2023 Feb 03.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/diagnosis
Humans ; COVID-19 Testing ; Limit of Detection ; RNA, Viral/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Efficient CRISPR-Cas13d-Based Antiviral Strategy to Combat SARS-CoV-2.
Autorzy:
Hussein M; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Andrade Dos Ramos Z; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Vink MA; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Kroon P; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Yu Z; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Enjuanes L; Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Zuñiga S; Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Berkhout B; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Herrera-Carrillo E; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
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Źródło:
Viruses [Viruses] 2023 Mar 06; Vol. 15 (3). Date of Electronic Publication: 2023 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*
Humans ; Antiviral Agents/pharmacology ; Gene Editing/methods ; RNA, Viral/genetics ; RNA, Viral/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions.
Autorzy:
Sommers JA; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA.
Loftus LN; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA.
Jones MP 3rd; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA.
Lee RA; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA.
Haren CE; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA.
Dumm AJ; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA.
Brosh RM Jr; Helicases and Genomic Integrity Section, Translational Gerontology Branch, National Institute on Aging, NIH, NIH Biomedical Research Center, Baltimore, Maryland, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102980. Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*/genetics
Humans ; DNA Helicases/metabolism ; Viral Nonstructural Proteins/genetics ; Viral Nonstructural Proteins/metabolism ; RNA ; Adenosine Triphosphate/metabolism ; RNA Helicases/genetics ; RNA Helicases/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Fidelity of Ribonucleotide Incorporation by the SARS-CoV-2 Replication Complex.
Autorzy:
Yin X; Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.
Popa H; Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.
Stapon A; Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.
Bouda E; Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794, USA.
Garcia-Diaz M; Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Mar 01; Vol. 435 (5), pp. 167973. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ribonucleotides*/metabolism
RNA-Dependent RNA Polymerase*/metabolism
SARS-CoV-2*/genetics
SARS-CoV-2*/physiology
Virus Replication*/genetics
Humans ; Kinetics ; RNA, Viral/genetics ; Viral Nonstructural Proteins/genetics ; Viral Nonstructural Proteins/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro.
Autorzy:
Miropolskaya N; Institute of Molecular Genetics, National Research Center 'Kurchatov Institute', Moscow, 123182, Russia.
Kozlov M; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia.
Petushkov I; Institute of Molecular Genetics, National Research Center 'Kurchatov Institute', Moscow, 123182, Russia.
Prostova M; Institute of Molecular Genetics, National Research Center 'Kurchatov Institute', Moscow, 123182, Russia.
Pupov D; Institute of Molecular Genetics, National Research Center 'Kurchatov Institute', Moscow, 123182, Russia.
Esyunina D; Institute of Molecular Genetics, National Research Center 'Kurchatov Institute', Moscow, 123182, Russia.
Kochetkov S; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991, Moscow, Russia.
Kulbachinskiy A; Institute of Molecular Genetics, National Research Center 'Kurchatov Institute', Moscow, 123182, Russia. Electronic address: .
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Źródło:
Biochimie [Biochimie] 2023 Mar; Vol. 206, pp. 81-88. Date of Electronic Publication: 2022 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*/genetics
Humans ; RNA, Viral/metabolism ; RNA-Dependent RNA Polymerase/genetics ; Viral Nonstructural Proteins/chemistry ; Antiviral Agents/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Optimization of the expression of the main protease from SARS-CoV-2.
Autorzy:
Rong Y; College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, People's Republic of China.
Zhang C; College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, People's Republic of China. Electronic address: .
Gao WC; College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, People's Republic of China.
Zhao C; College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, People's Republic of China. Electronic address: .
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Źródło:
Protein expression and purification [Protein Expr Purif] 2023 Mar; Vol. 203, pp. 106208. Date of Electronic Publication: 2022 Nov 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*/genetics
Humans ; Cysteine Endopeptidases/chemistry ; Protease Inhibitors/pharmacology ; Antiviral Agents/chemistry ; Molecular Docking Simulation
Czasopismo naukowe
Szczegóły
Tytuł:
Clinical accuracy of SARS-CoV-2 rapid antigen testing in screening children and adolescents.
Autorzy:
Krone M; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany; Institute for Hygiene and Microbiology, University of Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany. Electronic address: krone_.
Wagenhäuser I; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany; Department of Internal Medicine I, University Hospital Wuerzburg, Oberdürrbacher Str. 6, Wuerzburg 97080, Germany.
Knies K; Institute for Virology and Immunobiology, University of Wuerzburg, Versbacher Str. 7, Würzburg 97078, Germany.
Hofmann D; Institute for Virology and Immunobiology, University of Wuerzburg, Versbacher Str. 7, Würzburg 97078, Germany.
Engels G; Department of Paediatrics, University Hospital Wuerzburg, Wuerzburg, Germany.
Taurines R; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Margarete-Höppel-Platz 1, Würzburg 97080, Germany.
McDonogh M; Department of Orthopaedic Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberdürrbacher Str. 6, Wuerzburg 97080, Germany.
Flemming S; Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, University Hospital Wuerzburg, Oberdürrbacher Str. 6, Wuerzburg 97080, Germany.
Meyer T; Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, University Hospital Wuerzburg, Oberdürrbacher Str. 6, Wuerzburg 97080, Germany.
Böhm H; Department of Oral and Maxillofacial Surgery, University Hospital Wuerzburg, Pleicherwall 2, Wuerzburg 97070, Germany.
Scherzad A; Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University Hospital Wuerzburg, Josef-Schneider-Str. 11, Wuerzburg 97080, Germany.
Eisenmann M; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany.
Rauschenberger V; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany; Institute for Hygiene and Microbiology, University of Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany.
Gabel A; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany.
Petri N; Department of Internal Medicine I, University Hospital Wuerzburg, Oberdürrbacher Str. 6, Wuerzburg 97080, Germany.
Reusch J; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany; Department of Internal Medicine I, University Hospital Wuerzburg, Oberdürrbacher Str. 6, Wuerzburg 97080, Germany.
Forster J; Institute for Hygiene and Microbiology, University of Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany.
Weißbrich B; Institute for Virology and Immunobiology, University of Wuerzburg, Versbacher Str. 7, Würzburg 97078, Germany.
Dölken L; Institute for Virology and Immunobiology, University of Wuerzburg, Versbacher Str. 7, Würzburg 97078, Germany.
Kurzai O; Institute for Hygiene and Microbiology, University of Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany; Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute, Beutenbergstraße 13, Jena 07745, Germany.
Vogel U; Infection Control and Antimicrobial Stewardship Unit, University Hospital Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany; Institute for Hygiene and Microbiology, University of Wuerzburg, Josef-Schneider-Str. 2, Wuerzburg 97080, Germany.
Härtel C; Department of Paediatrics, University Hospital Wuerzburg, Wuerzburg, Germany.
Liese J; Department of Paediatrics, University Hospital Wuerzburg, Wuerzburg, Germany.
Andres O; Department of Paediatrics, University Hospital Wuerzburg, Wuerzburg, Germany.
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Źródło:
The Journal of infection [J Infect] 2023 Mar; Vol. 86 (3), pp. 256-308. Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*
COVID-19*/diagnosis
Humans ; Adolescent ; Child ; Sensitivity and Specificity ; Antigens, Viral
Raport
Szczegóły
Tytuł:
Immune Factors Drive Expression of SARS-CoV-2 Receptor Genes Amid Sexual Disparity.
Autorzy:
Vashisht A; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.; Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar 143005, India.
Ahluwalia P; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Mondal AK; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Singh H; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Sahajpal NS; Greenwood Genetic Center, Greenwood, SC 29646, USA.
Fulzele S; Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Kota V; Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Gahlay GK; Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar 143005, India.
Kolhe R; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
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Źródło:
Viruses [Viruses] 2023 Feb 28; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*/genetics
Humans ; Female ; Male ; Animals ; Mice ; Peptidyl-Dipeptidase A/metabolism ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Immunologic Factors ; Interferon Regulatory Factors/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Variations within the Glycan Shield of SARS-CoV-2 Impact Viral Spike Dynamics.
Autorzy:
Newby ML; School of Biological Sciences, University of Southampton, Southampton, UK. Electronic address: https://twitter.com/Maddy_Newby.
Fogarty CA; Department of Chemistry and Hamilton Institute, Maynooth University, Maynooth, Kildare, Ireland. Electronic address: https://twitter.com/2016Carl.
Allen JD; School of Biological Sciences, University of Southampton, Southampton, UK. Electronic address: https://twitter.com/JoelDalllen.
Butler J; School of Biological Sciences, University of Southampton, Southampton, UK.
Fadda E; Department of Chemistry and Hamilton Institute, Maynooth University, Maynooth, Kildare, Ireland. Electronic address: .
Crispin M; School of Biological Sciences, University of Southampton, Southampton, UK. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Feb 28; Vol. 435 (4), pp. 167928. Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Polysaccharides*/chemistry
Polysaccharides*/immunology
SARS-CoV-2*/chemistry
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Virus Attachment*
Immune Evasion*
Humans ; Antigens, Surface/chemistry ; Antigens, Surface/genetics ; Glycosylation
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents.
Autorzy:
Coombes NS; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Bewley KR; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Le Duff Y; Division of Infectious Disease Diagnostics, National Institute for Biological Standards, Medicines and Healthcare Products Regulatory Agency, Potters Bar EN6 3QG, UK.
Hurley M; Division of Infectious Disease Diagnostics, National Institute for Biological Standards, Medicines and Healthcare Products Regulatory Agency, Potters Bar EN6 3QG, UK.
Smith LJ; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Weldon TM; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Osman K; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Pullan S; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Berry N; Division of Infectious Disease Diagnostics, National Institute for Biological Standards, Medicines and Healthcare Products Regulatory Agency, Potters Bar EN6 3QG, UK.
Hallis B; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Charlton S; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Hall Y; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Funnell SGP; Medical Interventions Group, UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
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Źródło:
Viruses [Viruses] 2023 Feb 25; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/prevention & control
Humans ; COVID-19 Serotherapy ; Mutation ; Pandemics ; Antibodies, Neutralizing ; Antibodies, Viral ; Spike Glycoprotein, Coronavirus
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells.
Autorzy:
Zhang L; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Bisht P; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Flamier A; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Barrasa MI; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Friesen M; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Richards A; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Hughes SH; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Jaenisch R; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
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Źródło:
Viruses [Viruses] 2023 Feb 25; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*
Humans ; Reverse Transcription ; RNA, Messenger/genetics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Genomics
Czasopismo naukowe
Szczegóły
Tytuł:
Epitope Coverage of Anti-SARS-CoV-2 Nucleocapsid IgA and IgG Antibodies Correlates with Protection against Re-Infection by New Variants in Subsequent Waves of the COVID-19 Pandemic.
Autorzy:
Mullins MO; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Smith M; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Maboreke H; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Nel AJM; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Ntusi NAB; Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town 7925, South Africa.
Burgers WA; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Cape Town 7925, South Africa.; Division of Medical Virology, Department of Pathology, University of Cape Town, Cape Town 7925, South Africa.; Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Blackburn JM; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.; Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
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Źródło:
Viruses [Viruses] 2023 Feb 20; Vol. 15 (2). Date of Electronic Publication: 2023 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*
COVID-19*/epidemiology
Humans ; Epitopes ; Immunoglobulin G ; Pandemics ; Nucleocapsid ; Reinfection ; Immunoglobulin A
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ensitrelvir is effective against SARS-CoV-2 3CL protease mutants circulating globally.
Autorzy:
Kawashima S; Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Matsui Y; Laboratory for Bio-Drug Discovery, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Adachi T; Laboratory for Bio-Drug Discovery, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Morikawa Y; Laboratory for Bio-Drug Discovery, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Inoue K; Shionogi TechnoAdvance Research CO., LTD., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Takebayashi S; Shionogi TechnoAdvance Research CO., LTD., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Nobori H; Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Rokushima M; Laboratory for Bio-Drug Discovery, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Tachibana Y; Laboratory for Medicinal Chemistry Research, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan.
Kato T; Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1, Futaba-cho 3-chome, Toyonaka, Osaka, 561-0825, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Feb 19; Vol. 645, pp. 132-136. Date of Electronic Publication: 2023 Jan 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*
Humans ; Peptide Hydrolases ; Cysteine Endopeptidases/metabolism ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry ; Protease Inhibitors/pharmacology
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Distinct Conformations of SARS-CoV-2 Omicron Spike Protein and Its Interaction with ACE2 and Antibody.
Autorzy:
Lee M; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
Major M; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA.
Hong H; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Angiotensin-Converting Enzyme 2*/chemistry
Angiotensin-Converting Enzyme 2*/metabolism
COVID-19*/virology
SARS-CoV-2*/chemistry
SARS-CoV-2*/metabolism
Spike Glycoprotein, Coronavirus*/chemistry
Spike Glycoprotein, Coronavirus*/metabolism
Humans ; Antibodies, Neutralizing ; COVID-19 Vaccines ; Mutation ; Protein Binding ; Protein Conformation
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SARS-CoV-2 Harnesses Host Translational Shutoff and Autophagy To Optimize Virus Yields: the Role of the Envelope (E) Protein.
Autorzy:
Waisner H; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, Kansas, USA.
Grieshaber B; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, Kansas, USA.
Saud R; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, Kansas, USA.
Henke W; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, Kansas, USA.
Stephens EB; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, Kansas, USA.
Kalamvoki M; University of Kansas Medical Center, Department of Microbiology, Molecular Genetics, and Immunology, Kansas City, Kansas, USA.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2023 Feb 14; Vol. 11 (1), pp. e0370722. Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
SARS-CoV-2*/metabolism
Humans ; Autophagy ; Protein Processing, Post-Translational ; Viral Proteins/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Novel Affibody Molecules Specifically Bind to SARS-CoV-2 Spike Protein and Efficiently Neutralize Delta and Omicron Variants.
Autorzy:
Du W; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jiang P; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Li Q; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Wen H; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zheng M; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhang J; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Guo Y; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yang J; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Feng W; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ye S; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Kamara S; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jiang P; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chen J; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Li W; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhu S; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhang L; Institute of Molecular Virology and Immunology, Department of Microbiology and Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2023 Feb 14; Vol. 11 (1), pp. e0356222. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/prevention & control
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Spike Glycoprotein, Coronavirus*/genetics
Spike Glycoprotein, Coronavirus*/immunology
Humans ; Antibodies, Neutralizing ; Antibodies, Viral ; Molecular Docking Simulation ; Neutralization Tests/methods ; Recombinant Proteins
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Persistent memory despite rapid contraction of circulating T Cell responses to SARS-CoV-2 mRNA vaccination.
Autorzy:
Taus E; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Hofmann C; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Ibarrondo FJ; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Gong LS; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Hausner MA; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Fulcher JA; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Krogstad P; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.; Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Kitchen SG; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Ferbas KG; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Tobin NH; Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Rimoin AW; Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, United States.
Aldrovandi GM; Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Yang OO; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Feb 13; Vol. 14, pp. 1100594. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
SARS-CoV-2*
COVID-19*/prevention & control
Humans ; 2019-nCoV Vaccine mRNA-1273 ; Cross-Sectional Studies ; Leukocytes, Mononuclear ; Vaccination ; Cytokines ; Antibodies, Viral ; Enzyme-Linked Immunospot Assay
Czasopismo naukowe
Szczegóły
Tytuł:
Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2.
Autorzy:
Wang Y; Centre of Biomolecular Drug Research (BMWZ), Leibniz University Hannover, Schneiderberg 38, 30167 Hannover, Germany.
Kirkpatrick J; Centre of Biomolecular Drug Research (BMWZ), Leibniz University Hannover, Schneiderberg 38, 30167 Hannover, Germany; NMR-based Structural Chemistry, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany; School of Biosciences, University of Birmingham, Edgbaston, B15 2TT Birmingham, UK.
Lage SZ; NMR-based Structural Chemistry, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.
Carlomagno T; Centre of Biomolecular Drug Research (BMWZ), Leibniz University Hannover, Schneiderberg 38, 30167 Hannover, Germany; NMR-based Structural Chemistry, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany; School of Biosciences, University of Birmingham, Edgbaston, B15 2TT Birmingham, UK; Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, B15 2TT Birmingham, UK. Electronic address: .
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Źródło:
Structure (London, England : 1993) [Structure] 2023 Feb 02; Vol. 31 (2), pp. 128-137.e5. Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Humans ; Protein Binding ; RNA, Messenger/metabolism ; Viral Nonstructural Proteins/chemistry
Czasopismo naukowe
Szczegóły
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