Temat: "secretion" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: High-Throughput Quantitative Screening of Glucose-Stimulated Insulin Secretion and Insulin Content Using Automated MALDI-TOF Mass Spectrometry.
Autorzy:: Delannoy CP; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, CNRS, U1283-UMR 8199-EGID, F-59000 Lille, France.
Heuson E; Univ. Lille, CNRS, Centrale Lille, Univ. Artois, UMR 8181-UCCS-Unité de Catalyse et de Chimie du Solide, F-59000 Lille, France.
Herledan A; Univ. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecule for Living Systems, F-59000 Lille, France.
Oger F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, CNRS, U1283-UMR 8199-EGID, F-59000 Lille, France.
Thiroux B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, CNRS, U1283-UMR 8199-EGID, F-59000 Lille, France.
Chevalier M; Univ. Lille, UMRt BioEcoAgro 1158-INRAE, Équipe Métabolites Secondaires D'origine Microbienne, Institut Charles Viollette, F-59000 Lille, France.
Gromada X; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, CNRS, U1283-UMR 8199-EGID, F-59000 Lille, France.
Rolland L; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE-Facteurs de Risque et Determinants Moléculaires des Maladies liées au Vieillissement, F-59000 Lille, France.
Froguel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, CNRS, U1283-UMR 8199-EGID, F-59000 Lille, France.
Deprez B; Univ. Lille, Inserm, Institut Pasteur de Lille, U1177-Drugs and Molecule for Living Systems, F-59000 Lille, France.
Paul S; Univ. Lille, CNRS, Centrale Lille, Univ. Artois, UMR 8181-UCCS-Unité de Catalyse et de Chimie du Solide, F-59000 Lille, France.
Annicotte JS; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE-Facteurs de Risque et Determinants Moléculaires des Maladies liées au Vieillissement, F-59000 Lille, France.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Mar 09; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin*/metabolism
Diabetes Mellitus, Type 2*/metabolism
Humans ; Animals ; Mice ; Insulin Secretion ; Glucose/pharmacology ; Glucose/metabolism ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; High-Throughput Screening Assays ; Insulin, Regular, Human/metabolism

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Skocz do pozycji: 2.

Tytuł:: Effects of silibinin on apoptosis and insulin secretion in rat RINm5F pancreatic β-cells.
Autorzy:: Mazraesefidi M; Department of Clinical Biochemistry, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mahmoodi M; Department of Clinical Biochemistry, Afzalipoor Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Hajizadeh M; Department of Clinical Biochemistry, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.; Molecular Medicine Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.; Pokaż więcej
Źródło:: Biotechnic & histochemistry : official publication of the Biological Stain Commission [Biotech Histochem] 2023 Apr; Vol. 98 (3), pp. 201-209. Date of Electronic Publication: 2023 Feb 10.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin*/metabolism
Glucose*
Rats ; Animals ; Insulin Secretion ; Silybin ; Apoptosis

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Skocz do pozycji: 3.

Tytuł:: Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells.
Autorzy:: Pavluch V; Department of Mitochondrial Physiology, No. 75, Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, 14220, Czech Republic.
Engstová H; Department of Mitochondrial Physiology, No. 75, Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, 14220, Czech Republic.
Špačková J; Department of Mitochondrial Physiology, No. 75, Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, 14220, Czech Republic.
Ježek P; Department of Mitochondrial Physiology, No. 75, Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, 14220, Czech Republic. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jan 13; Vol. 13 (1), pp. 683. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin*/metabolism
Insulin-Secreting Cells*/metabolism
Homeodomain Proteins*/genetics
Homeodomain Proteins*/metabolism
Animals ; Rats ; Adenosine Triphosphate/metabolism ; Glucose/metabolism ; Insulin Secretion ; Transcription Factors/genetics ; Transcription Factors/metabolism

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Skocz do pozycji: 4.

Tytuł:: Exosomes Secreted by Umbilical Cord Blood-Derived Mesenchymal Stem Cell Attenuate Diabetes in Mice.
Autorzy:: Sharma R; Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.
Kumari M; Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.
Mishra S; Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.
Chaudhary DK; Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.
Kumar A; Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.
Avni B; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah-Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel.; Faculty of Medicine, Hebrew University of Jerusalem, Israel.
Tiwari S; Department of Molecular Medicine & Biotechnology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India.; Pokaż więcej
Źródło:: Journal of diabetes research [J Diabetes Res] 2021 Dec 10; Vol. 2021, pp. 9534574. Date of Electronic Publication: 2021 Dec 10 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Cord Blood Stem Cell Transplantation*
Insulin Secretion*
Blood Glucose/*metabolism
Diabetes Mellitus, Experimental/*surgery
Exosomes/*transplantation
Insulin/*blood
Insulin-Secreting Cells/*metabolism
Animals ; Biomarkers/blood ; Cell Proliferation ; Cells, Cultured ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/chemically induced ; Diabetes Mellitus, Experimental/pathology ; Exosomes/genetics ; Exosomes/metabolism ; Gene Expression Regulation ; Humans ; Insulin-Secreting Cells/pathology ; Lymphocyte Activation ; Male ; Mice, Inbred C57BL ; Regeneration ; Signal Transduction ; Streptozocin ; T-Lymphocytes/metabolism ; Mice

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Skocz do pozycji: 5.

Tytuł:: Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.
Autorzy:: Miyachi Y; Department of Medicine and Naomi Berrie Diabetes Center, Vagelos College of Physicians & Surgeons of Columbia University, New York, New York, United States of America.
Kuo T; Department of Medicine and Naomi Berrie Diabetes Center, Vagelos College of Physicians & Surgeons of Columbia University, New York, New York, United States of America.
Son J; Department of Medicine and Naomi Berrie Diabetes Center, Vagelos College of Physicians & Surgeons of Columbia University, New York, New York, United States of America.
Accili D; Department of Medicine and Naomi Berrie Diabetes Center, Vagelos College of Physicians & Surgeons of Columbia University, New York, New York, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Nov 29; Vol. 16 (11), pp. e0260526. Date of Electronic Publication: 2021 Nov 29 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin Secretion*
Aldo-Keto Reductases/*metabolism
Insulin/*metabolism
Insulin-Secreting Cells/*metabolism
Aldo-Keto Reductases/genetics ; Animals ; Cell Line ; Cells, Cultured ; Female ; Gene Deletion ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout

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Skocz do pozycji: 6.

Tytuł:: Insulin secretion and action after pancreas transplantation. A retrospective single-center study.
Autorzy:: Bleskestad KB; Department of Transplantation Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Nordheim E; Department of Transplantation Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Lindahl JP; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Midtvedt K; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Pihlstrøm HK; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Horneland R; Section of Transplant Surgery, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Lee S; Department of Transplantation Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Åsberg A; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.; Department of Pharmacy, University of Oslo, Oslo, Norway.
Jenssen TG; Department of Transplantation Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Birkeland KI; Department of Transplantation Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Nephrology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.; Pokaż więcej
Źródło:: Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 2021 Sep; Vol. 81 (5), pp. 365-370. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin Secretion*
Pancreas Transplantation*
Diabetes Mellitus, Type 1/*surgery
Insulin/*pharmacology
Adult ; Blood Glucose/analysis ; Diabetes Mellitus, Type 1/metabolism ; Female ; Glomerular Filtration Rate ; Humans ; Insulin Resistance ; Kidney Transplantation ; Male ; Middle Aged ; Retrospective Studies

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Skocz do pozycji: 7.

Tytuł:: Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells.
Autorzy:: Kabra UD; Division of Metabolic Diseases, Technische Universität München, 80333 Munich, Germany.; Department of Pharmaceutical Chemistry, Parul Institute of Pharmacy, Parul University, Vadodara 391760, Gujarat, India.
Moruzzi N; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
Berggren PO; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
Jastroch M; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 15; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 15.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin*/metabolism
Insulin-Secreting Cells*/metabolism
Insulin Secretion ; Mitochondrial Dynamics/genetics ; Glucose/metabolism ; Insulin, Regular, Human

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Skocz do pozycji: 8.

Tytuł:: A radioligand receptor binding assay for measuring of insulin secreted by MIN6 cells after stimulation with glucose, arginine, ornithine, dopamine, and serotonin.
Autorzy:: Asai S; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.; Department of Biochemistry, Faculty of Science, Charles University, 12840, Prague 2, Czech Republic.
Žáková L; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.
Selicharová I; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.
Marek A; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic.
Jiráček J; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 116 10, Prague 6, Czech Republic. .; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Jul; Vol. 413 (17), pp. 4531-4543. Date of Electronic Publication: 2021 May 29.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin Secretion*
Insulin/*analysis
Insulin/*metabolism
Animals ; Arginine/metabolism ; Cell Line ; Dopamine/metabolism ; Glucose/metabolism ; Humans ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Mice ; Ornithine/metabolism ; Radioimmunoassay/methods ; Radioligand Assay/methods ; Rats ; Rats, Wistar ; Serotonin/metabolism

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Skocz do pozycji: 9.

Tytuł:: Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research.
Autorzy:: Casas B; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Department of Biomedical Engineering, Linköping University, Linköping, Sweden.
Vilén L; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Bauer S; TissUse GmbH, Berlin, Germany.
Kanebratt KP; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Wennberg Huldt C; Bioscience, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Magnusson L; Bioscience, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Marx U; TissUse GmbH, Berlin, Germany.
Andersson TB; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Gennemark P; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Department of Biomedical Engineering, Linköping University, Linköping, Sweden.
Cedersund G; Department of Biomedical Engineering, Linköping University, Linköping, Sweden.; Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2022 Oct 19; Vol. 18 (10), pp. e1010587. Date of Electronic Publication: 2022 Oct 19 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin*/metabolism
Diabetes Mellitus*/metabolism
Animals ; Humans ; Glucose/metabolism ; Liver/metabolism ; Insulin Secretion ; Blood Glucose/metabolism

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Skocz do pozycji: 10.

Tytuł:: Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V.
Autorzy:: Lubberding AF; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Zhang J; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Lundh M; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nielsen TS; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Søndergaard MS; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Villadsen M; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Skovhøj EZ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Boer GA; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Hansen JB; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Thomsen MB; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Treebak JT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Holst JJ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kanters JK; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Mandrup-Poulsen T; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Jespersen T; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Emanuelli B; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Torekov SS; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark. .; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jun 10; Vol. 11 (1), pp. 12253. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin Secretion*
Loss of Function Mutation*
Insulin/*biosynthesis
Islets of Langerhans/*metabolism
KCNQ1 Potassium Channel/*genetics
Long QT Syndrome/*metabolism
Long QT Syndrome/*physiopathology
Alleles ; Amino Acid Substitution ; Animals ; Disease Models, Animal ; Disease Susceptibility ; Glucose/metabolism ; Long QT Syndrome/etiology ; Mice

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Skocz do pozycji: 11.

Tytuł:: Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection.
Autorzy:: Chatterjee Bhowmick D; Department of Molecular and Cellular Endocrinology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Ahn M; Department of Molecular and Cellular Endocrinology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Oh E; Department of Molecular and Cellular Endocrinology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Veluthakal R; Department of Molecular and Cellular Endocrinology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Thurmond DC; Department of Molecular and Cellular Endocrinology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 12; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Exocytosis*
Insulin Secretion*
Diabetes Mellitus, Type 2/*metabolism
Insulin/*metabolism
Insulin-Secreting Cells/*metabolism
SNARE Proteins/*metabolism
Animals ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/pathology ; Humans ; Insulin/genetics ; Insulin-Secreting Cells/pathology ; SNARE Proteins/genetics ; Signal Transduction

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Skocz do pozycji: 12.

Tytuł:: Maternal stress induced endoplasmic reticulum stress and impaired pancreatic islets' insulin secretion via glucocorticoid receptor upregulation in adult male rat offspring.
Autorzy:: Salimi M; Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, PO Box: 5166614756, Tabriz, Iran.
Eskandari F; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, PO Box: 19615-1178, Tehran, Iran.
Binayi F; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, PO Box: 19615-1178, Tehran, Iran.
Eliassi A; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, PO Box: 19615-1178, Tehran, Iran.; Neurophysiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ghanbarian H; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hedayati M; Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fahanik-Babaei J; Electrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Eftekhary M; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Keyhanmanesh R; Department of Physiology, Faculty of Medicine, Tabriz University of Medical Sciences, PO Box: 5166614756, Tabriz, Iran. .; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. .
Zardooz H; Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, PO Box: 19615-1178, Tehran, Iran. homeira_.; Neurophysiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. homeira_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jul 22; Vol. 12 (1), pp. 12552. Date of Electronic Publication: 2022 Jul 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin*/metabolism
Islets of Langerhans*/metabolism
Animals ; Calmodulin-Binding Proteins/genetics ; Endoplasmic Reticulum Stress ; Female ; Glucocorticoids/pharmacology ; Glucose/metabolism ; Insulin Secretion ; Male ; Membrane Proteins/metabolism ; Pregnancy ; Rats ; Receptors, Glucocorticoid/genetics ; Receptors, Glucocorticoid/metabolism ; Up-Regulation

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Skocz do pozycji: 13.

Tytuł:: Impaired insulin secretion and related factors in East Asian individuals.
Autorzy:: Nakamura A; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Terauchi Y; Department of Endocrinology and Metabolism, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.; Pokaż więcej
Źródło:: Journal of diabetes investigation [J Diabetes Investig] 2022 Feb; Vol. 13 (2), pp. 233-235. Date of Electronic Publication: 2021 Sep 24.
Typ publikacji:: Journal Article
MeSH Terms:: Asian People*
Insulin*/metabolism
Humans ; Insulin Secretion

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Skocz do pozycji: 14.

Tytuł:: Substantial inter-individual variations in insulin secretion and sensitivity across the glucometabolic spectrum.
Autorzy:: Hansen AMB; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Wium C; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
Lee S; Department of Nutrition, Faculty of Medicine, Institute of Basic Medical Science, University of Oslo, Oslo, Norway.
Tierney AC; Nutrigenomics Research Group, UCD Conway Institute & UCD Institute of Food and Health, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.; School of Allied Health, University of Limerick, Limerick, Ireland.; School of Allied Health, La Trobe University, Melbourne, Australia.
McCarthy D; Department of Food Biosciences, The Hugh Sinclair Unit of Human Nutrition, University of Reading, Reading, UK.; Institute for Global Food Security, Northern Ireland Technology Centre, Queen's University Belfast, Belfast, Northern Ireland.
Roche HM; Nutrigenomics Research Group, UCD Conway Institute & UCD Institute of Food and Health, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.
Drevon CA; Department of Nutrition, Faculty of Medicine, Institute of Basic Medical Science, University of Oslo, Oslo, Norway.
Birkeland KI; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway.
Gulseth HL; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.; Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.; Pokaż więcej
Źródło:: Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 2020 Jul; Vol. 80 (4), pp. 282-290. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin Secretion*
Blood Glucose/*metabolism
Diabetes Mellitus, Type 2/*blood
Insulin/*blood
Metabolic Syndrome/*blood
Adult ; Aged ; Area Under Curve ; Biological Variation, Individual ; Blood Pressure/physiology ; Body Mass Index ; Cholesterol, HDL/blood ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/pathology ; Female ; Glucose Clamp Technique/methods ; Glucose Tolerance Test ; Humans ; Insulin Resistance ; Male ; Metabolic Syndrome/pathology ; Middle Aged ; Triglycerides/blood ; Waist-Hip Ratio

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Skocz do pozycji: 15.

Tytuł:: Pharmacological polysulfide suppresses glucose-stimulated insulin secretion in an ATP-sensitive potassium channel-dependent manner.
Autorzy:: Shoji T; Department of Anesthesiology, Kansai Medical University, Hirakata, Japan.; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.
Hayashi M; Department of Cell Physiology, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.
Sumi C; Department of Anesthesiology, Kansai Medical University, Hirakata, Japan.; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.
Kusunoki M; Department of Anesthesiology, Kansai Medical University, Hirakata, Japan.; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.
Uba T; Department of Anesthesiology, Kansai Medical University, Hirakata, Japan.; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.
Matsuo Y; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan.
Kimura H; Department of Pharmacology, Faculty of Pharmaceutical Science, Sanyo-Onoda City University, Sanyo-Onoda, Japan.; Department of Molecular Pharmacology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan.
Hirota K; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Dec 18; Vol. 9 (1), pp. 19377. Date of Electronic Publication: 2019 Dec 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Insulin/*metabolism
Insulin Secretion/*drug effects
Insulin-Secreting Cells/*drug effects
KATP Channels/*antagonists & inhibitors
Sulfides/*pharmacology
Adenosine Triphosphate/metabolism ; Animals ; Calcium/metabolism ; Cell Line ; Glucose/metabolism ; Glucose/pharmacology ; Humans ; Hydrogen Sulfide/metabolism ; Insulin/biosynthesis ; Insulin Secretion/genetics ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/pathology ; KATP Channels/metabolism ; Mice ; Oxygen/metabolism ; Rats ; Signal Transduction/drug effects

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Skocz do pozycji: 16.

Tytuł:: Leaner Women with Impaired Insulin Secretion Accounts for about 40% of Gestational Diabetes Mellitus in Japan.
Autorzy:: Furukawa S; Department of Obstetrics & Gynecology, School of Medicine, Kyorin University, Tokyo, Japan.
Kobayashi Y; Department of Obstetrics & Gynecology, School of Medicine, Kyorin University, Tokyo, Japan.; Pokaż więcej
Źródło:: Journal of pregnancy [J Pregnancy] 2019 Jun 02; Vol. 2019, pp. 7578403. Date of Electronic Publication: 2019 Jun 02 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Insulin Secretion*
Thinness*
Diabetes, Gestational/*etiology
Insulin/*deficiency
Adult ; Biomarkers/blood ; Body Mass Index ; Cross-Sectional Studies ; Diabetes, Gestational/blood ; Diabetes, Gestational/diagnosis ; Diabetes, Gestational/epidemiology ; Female ; Glucose Tolerance Test ; Humans ; Insulin/blood ; Japan/epidemiology ; Pregnancy ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity

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Skocz do pozycji: 17.

Tytuł:: Copine 3 "CPNE3" is a novel regulator for insulin secretion and glucose uptake in pancreatic β-cells.
Autorzy:: El-Huneidi W; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.
Anjum S; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.
Mohammed AK; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.
Unnikannan H; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.
Saeed R; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.
Bajbouj K; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.
Abu-Gharbieh E; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates.; Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Taneera J; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates. .; University of Sharjah, Sharjah Institute for Medical Research, Sharjah, United Arab Emirates. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Oct 19; Vol. 11 (1), pp. 20692. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carrier Proteins/*metabolism
Glucose/*metabolism
Insulin/*metabolism
Insulin Secretion/*physiology
Insulin-Secreting Cells/*metabolism
Cells, Cultured ; Diabetes Mellitus, Type 2/metabolism ; Humans

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Skocz do pozycji: 18.

Tytuł:: Exploring Insulin Production Following Alveolar Islet Transplantation (AIT).
Autorzy:: Lau H; Department of Surgery, University of California, Irvine (UCI), Orange, CA 92868, USA.
Khosrawipour T; Department of Surgery (A), University-Hospital Düsseldorf, Heinrich-Heine University, Moorenstrasse 5, D-40225 Duesseldorf, Germany.
Li S; Department of Surgery, Weill Medical College of Cornell University, New York, NY 10065, USA.
Alexander M; Department of Surgery, University of California, Irvine (UCI), Orange, CA 92868, USA.
Frelkiewicz P; Center for Experimental Diagnostics and Biomedical Innovations, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Labbé MK; School of Dentistry, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Stieglitz S; Department Pulmonary Medicine, Petrus-Hospital Wuppertal, University of Witten-Herdecke, D-42283 Wuppertal, Germany.
Lakey JRT; Department of Surgery, University of California, Irvine (UCI), Orange, CA 92868, USA.
Kielan W; 2nd Department of General Surgery and Surgical Oncology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Khosrawipour V; Department of Surgery, University of California, Irvine (UCI), Orange, CA 92868, USA.; 2nd Department of General Surgery and Surgical Oncology, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 22; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 22.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin/*biosynthesis
Insulin Secretion/*physiology
Islets of Langerhans/*metabolism
Islets of Langerhans Transplantation/*methods
Pulmonary Alveoli/*surgery
Administration, Inhalation ; Aerosols/administration & dosage ; Animals ; Blood Glucose/analysis ; Diabetes Mellitus, Type 1/therapy ; Glucose/administration & dosage ; Glucose/metabolism ; Swine

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Skocz do pozycji: 19.

Tytuł:: Inceptor intercepts insulin signaling in pancreatic β-cells.
Autorzy:: Watada H; Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Pokaż więcej
Źródło:: Journal of diabetes investigation [J Diabetes Investig] 2021 Sep; Vol. 12 (9), pp. 1540-1541. Date of Electronic Publication: 2021 Jul 04.
Typ publikacji:: Journal Article; Comment
MeSH Terms:: Insulin*/metabolism
Insulin-Secreting Cells*/metabolism
Insulin Secretion ; Signal Transduction

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Skocz do pozycji: 20.

Tytuł:: Tacrolimus inhibits insulin release and promotes apoptosis of Min6 cells through the inhibition of the PI3K/Akt/mTOR pathway.
Autorzy:: Tong L; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Li W; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Zhang Y; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Zhou F; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Zhao Y; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Zhao L; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Liu J; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Song Z; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Yu M; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Zhou C; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.
Yu A; Department of Clinical Pharmacy, General Hospital of Central Theater Command, Wuhan, Hubei 430000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Sep; Vol. 24 (3). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Insulin/*metabolism
Insulin Secretion/*drug effects
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Tacrolimus/*pharmacology
Animals ; Caspase 3/metabolism ; Cell Line, Tumor ; Diabetes Mellitus ; Insulinoma/drug therapy ; Insulinoma/metabolism ; Mice ; Oxidative Stress ; Phosphorylation ; Signal Transduction/drug effects

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