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Wyszukujesz frazę ""serotonin"" wg kryterium: Temat


Starter badań:

Tytuł :
Déjà-vu? Neural and behavioural effects of the 5-HT 4 receptor agonist, prucalopride, in a hippocampal-dependent memory task.
Autorzy :
de Cates AN; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK. .; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK. .
Wright LC; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Martens MAG; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
Gibson D; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Türkmen C; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Filippini N; IRCCS San Camillo Hospital, Venice, Italy.
Cowen PJ; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Harmer CJ; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.; Oxford Centre for Human Brain Activity, Wellcome Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford, UK.
Murphy SE; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
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Źródło :
Translational psychiatry [Transl Psychiatry] 2021 Oct 04; Vol. 11 (1), pp. 497. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Serotonin*
Serotonin 5-HT4 Receptor Agonists*/pharmacology
Benzofurans ; Hippocampus/metabolism ; Humans ; Receptors, Serotonin, 5-HT4/metabolism
Czasopismo naukowe
Tytuł :
The Modulatory Role of Serotonin on Human Impulsive Aggression.
Autorzy :
da Cunha-Bang S; Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark; Psychiatric Center North Zealand, Mental Health Services in the Capital Region of Denmark, Hillerød, Denmark. Electronic address: .
Knudsen GM; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Biological psychiatry [Biol Psychiatry] 2021 Oct 01; Vol. 90 (7), pp. 447-457. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Aggression*
Serotonin*
Brain/diagnostic imaging ; Brain/metabolism ; Humans ; Impulsive Behavior ; Monoamine Oxidase/genetics ; Monoamine Oxidase/metabolism ; Serotonin Plasma Membrane Transport Proteins/genetics ; Serotonin Plasma Membrane Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
A comprehensive assessment of genetic variation in serotonin transporter gene (5-HTTLPR+rs25531) and the response to dapoxetine in Chinese patients with premature ejaculation.
Autorzy :
Huang Y; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Gao J; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Gao P; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Peng D; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Dai Y; Department of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China.
Jiang H; Department of Andrology, Peking University Third Hospital, Beijing, China.; Department of Human Sperm Bank, Peking University Third Hospital, Beijing, China.
Zhang X; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
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Źródło :
Andrologia [Andrologia] 2021 Sep; Vol. 53 (8), pp. e14141. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Premature Ejaculation*/drug therapy
Premature Ejaculation*/genetics
Serotonin Plasma Membrane Transport Proteins*/genetics
Benzylamines ; China ; Ejaculation ; Humans ; Male ; Naphthalenes ; Polymorphism, Genetic ; Serotonin Uptake Inhibitors/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Antidepressant efficacy of Agomelatine: Meta-analysis of placebo controlled and active comparator studies.
Autorzy :
Maddukuri RK; Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India. Electronic address: .
Hema C; Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India. Electronic address: .
Sri Tejaswi K; Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India. Electronic address: .
Venkata Mounika M; Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India. Electronic address: .
Vegesana BP; Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India. Electronic address: .
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Źródło :
Asian journal of psychiatry [Asian J Psychiatr] 2021 Nov; Vol. 65, pp. 102866. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Acetamides*/adverse effects
Serotonin and Noradrenaline Reuptake Inhibitors*
Adult ; Antidepressive Agents/adverse effects ; Humans ; Serotonin Uptake Inhibitors
Czasopismo naukowe
Tytuł :
Folate as adjunct therapy to SSRI/SNRI for major depressive disorder: Systematic review & meta-analysis.
Autorzy :
Altaf R; Department of Physician Assistant Studies, 5151 Park Ave, Sacred Heart University, Fairfield, CT, 06825, United States. Electronic address: .
Gonzalez I; Department of Physician Assistant Studies, 5151 Park Ave, Sacred Heart University, Fairfield, CT, 06825, United States. Electronic address: .
Rubino K; Psychiatry Department, Contemporary Care-Greenwich, 81 Holly Hill Ln, Greenwich, CT, 06830, United States. Electronic address: .
Nemec EC 2nd; Department of Physician Assistant Studies, 5151 Park Ave, Sacred Heart University, Fairfield, CT, 06825, United States. Electronic address: .
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Źródło :
Complementary therapies in medicine [Complement Ther Med] 2021 Sep; Vol. 61, pp. 102770. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms :
Depressive Disorder, Major*/drug therapy
Serotonin and Noradrenaline Reuptake Inhibitors*
Folic Acid ; Humans ; Serotonin Uptake Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Lasmiditan for the acute treatment of migraine.
Autorzy :
DeJulio PA; Department of Emergency Medicine, The Ohio State University, OH 43210, USA.; Department of Internal Medicine, The Ohio State University, OH 43210, USA.
Perese JK; Department of Emergency Medicine, Loma Linda University Medical Center, CA 92354, USA.
Schuster NM; Department of Anesthesiology, Center for Pain Medicine, UC San Diego Health, CA 92103, USA.
Oswald JC; Department of Anesthesiology, Center for Pain Medicine, UC San Diego Health, CA 92103, USA.; Department of Emergency Medicine, UC San Diego Health, CA 92103, USA.
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Źródło :
Pain management [Pain Manag] 2021 Sep; Vol. 11 (5), pp. 437-449. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Migraine Disorders*/drug therapy
Serotonin Receptor Agonists*
Benzamides ; Humans ; Piperidines ; Pyridines ; Receptors, Serotonin
Czasopismo naukowe
Tytuł :
Drug interaction between a selective serotonin reuptake inhibitor and a triptan leading to serotonin toxicity: a case report and review of the literature.
Autorzy :
Jin G; Redcliffe Hospital, Anzac Avenue, Redcliffe, QLD, 4020, Australia. .
Stokes P; Redcliffe Hospital, Anzac Avenue, Redcliffe, QLD, 4020, Australia.
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Źródło :
Journal of medical case reports [J Med Case Rep] 2021 Jul 26; Vol. 15 (1), pp. 371. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Serotonin*
Serotonin Uptake Inhibitors*/adverse effects
Adult ; Drug Interactions ; Female ; Humans ; Serotonin Receptor Agonists ; Tryptamines/adverse effects
Czasopismo naukowe
Tytuł :
Characteristics of patients with major depressive disorder switching SSRI/SNRI therapy compared with those augmenting with an atypical antipsychotic in a real-world setting.
Autorzy :
Kern DM; Janssen Research & Development LLC, Titusville, NJ, USA.
Cepeda MS; Janssen Research & Development LLC, Titusville, NJ, USA.
Castilla-Puentes RC; Janssen Research & Development LLC, Titusville, NJ, USA.
Savitz A; Janssen Research & Development LLC, Titusville, NJ, USA.
Etropolski M; Janssen Research & Development LLC, Titusville, NJ, USA.
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Źródło :
Current medical research and opinion [Curr Med Res Opin] 2021 Aug; Vol. 37 (8), pp. 1377-1384. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antipsychotic Agents*/therapeutic use
Depressive Disorder, Major*/drug therapy
Depressive Disorder, Major*/epidemiology
Serotonin and Noradrenaline Reuptake Inhibitors*/therapeutic use
Humans ; Norepinephrine ; Serotonin/therapeutic use ; Serotonin Uptake Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Modulation of the 5-HT 3 A receptor current by desacylbaldrinal.
Autorzy :
Wang LX; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chen HL; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yan HL; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Tang F; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhang H; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Li HX; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ye Q; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Peng C; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Tan YZ; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
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Źródło :
Natural product research [Nat Prod Res] 2021 Aug; Vol. 35 (16), pp. 2758-2762. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Receptors, Serotonin, 5-HT3*
Serotonin*
Iridoids/*pharmacology
Serotonin 5-HT3 Receptor Antagonists/*pharmacology
Valerian/*chemistry
Humans ; Iridoids/isolation & purification ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Serotonin 5-HT3 Receptor Antagonists/isolation & purification
Czasopismo naukowe
Tytuł :
Serotonin Syndrome Induced by a Single Dose of Venlafaxine and Magnesium Valproate.
Autorzy :
Zhan Z; Emergency Department, The First Affiliated Hospital of Nanchang University, Jiangxi, China, .
Cao CS
Huang L
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Źródło :
Psychiatria Danubina [Psychiatr Danub] 2021 Summer; Vol. 33 (2), pp. 193-195.
Typ publikacji :
Journal Article
MeSH Terms :
Serotonin Syndrome*/chemically induced
Valproic Acid*/adverse effects
Cyclohexanols ; Humans ; Serotonin ; Serotonin Uptake Inhibitors ; Venlafaxine Hydrochloride/adverse effects
Czasopismo naukowe
Tytuł :
The Relationship between Genotype of Serotonin-transporter-linked Polymorphic Region (5-HTTLPR) and Migraine combined with Depression.
Autorzy :
Han L; Department of Psychosomatic, Mental Health Center, Zhejiang University School of Medicine, China.
Yu Z; Department of Psychosomatic, Mental Health Center, Zhejiang University School of Medicine, China.
Mao H; Department of Psychosomatic, Mental Health Center, Zhejiang University School of Medicine, China.
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Źródło :
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2021 Aug; Vol. 31 (8), pp. 998-1000.
Typ publikacji :
Journal Article
MeSH Terms :
Migraine Disorders*/genetics
Serotonin*
Alleles ; China/epidemiology ; Depression/epidemiology ; Depression/genetics ; Genotype ; Humans ; Polymorphism, Genetic ; Serotonin Plasma Membrane Transport Proteins/genetics
Czasopismo naukowe
Tytuł :
Large-scale network dynamics in neural response to emotionally negative stimuli linked to serotonin 1A binding in major depressive disorder.
Autorzy :
Schneck N; Department of Psychiatry, Columbia University, New York, NY, USA. .; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA. .
Tu T; Department of Biomedical Engineering, Columbia University, New York, NY, USA.
Falcone HR; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Miller JM; Department of Psychiatry, Columbia University, New York, NY, USA.; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Zanderigo F; Department of Psychiatry, Columbia University, New York, NY, USA.; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Sublette ME; Department of Psychiatry, Columbia University, New York, NY, USA.; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Oquendo MA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Stanley B; Department of Psychiatry, Columbia University, New York, NY, USA.; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Burke A; Department of Psychiatry, Columbia University, New York, NY, USA.; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Ochsner K; Department of Psychology, Columbia University, New York, NY, USA.
Sajda P; Department of Biomedical Engineering, Columbia University, New York, NY, USA.; Data Science Institute, Columbia University, New York, NY, USA.
John Mann J; Department of Psychiatry, Columbia University, New York, NY, USA.; Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
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Źródło :
Molecular psychiatry [Mol Psychiatry] 2021 Jun; Vol. 26 (6), pp. 2393-2401. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
Depressive Disorder, Major*/diagnostic imaging
Serotonin*
Brain/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Receptor, Serotonin, 5-HT1A
Czasopismo naukowe
Tytuł :
The Effect of Serotonin Receptor 5-HT1B on Lateral Inhibition between Spiny Projection Neurons in the Mouse Striatum.
Autorzy :
Pommer S; Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, Okinawa 904-0495, Japan.
Akamine Y; Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, Okinawa 904-0495, Japan.
Schiffmann SN; Laboratory of Neurophysiology, Université Libre de Bruxelles Neuroscience Institute, Université Libre de Bruxelles, Brussels 1070, Belgium.
de Kerchove d'Exaerde A; Laboratory of Neurophysiology, Université Libre de Bruxelles Neuroscience Institute, Université Libre de Bruxelles, Brussels 1070, Belgium.
Wickens JR; Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, Okinawa 904-0495, Japan .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Sep 15; Vol. 41 (37), pp. 7831-7847. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Corpus Striatum/*drug effects
Neural Inhibition/*drug effects
Neurons/*drug effects
Receptor, Serotonin, 5-HT1B/*metabolism
Serotonin 5-HT1 Receptor Agonists/*pharmacology
Action Potentials/drug effects ; Animals ; Corpus Striatum/metabolism ; Interneurons/drug effects ; Interneurons/metabolism ; Mice ; Neurons/metabolism ; Patch-Clamp Techniques ; Serotonin/metabolism ; Synaptic Transmission/drug effects ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł :
Synaptic mechanism underlying serotonin modulation of transition to cocaine addiction.
Autorzy :
Li Y; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Simmler LD; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Van Zessen R; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Flakowski J; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA.
Wan JX; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Deng F; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Li YL; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Nautiyal KM; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA.
Pascoli V; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.
Lüscher C; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland.; IDG McGovern Institute for Brain Research, Peking University, Beijing 100871, China.; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA.; Clinic of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, CH-1211 Geneva, Switzerland.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Sep 10; Vol. 373 (6560), pp. 1252-1256. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Synaptic Transmission*
Cocaine-Related Disorders/*metabolism
Receptor, Serotonin, 5-HT1B/*metabolism
Serotonin/*metabolism
Animals ; Cocaine/administration & dosage ; Cocaine-Related Disorders/genetics ; Dopamine/metabolism ; Gene Knock-In Techniques ; Mice ; Mice, Knockout ; Optogenetics ; Receptor, Serotonin, 5-HT1B/deficiency ; Serotonin Plasma Membrane Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Synthesis and biological evaluation of 1-(4-(piperazin-1-yl)phenyl)pyridin-2(1H)-one derivatives as potential SSRIs.
Autorzy :
Xu T; Sunshine Lake Pharma Co. Ltd., Shenzhen, 518000, PR China; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, PR China.
Xue Y; Sunshine Lake Pharma Co. Ltd., Shenzhen, 518000, PR China; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, PR China.
Lu J; Sunshine Lake Pharma Co. Ltd., Shenzhen, 518000, PR China; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, PR China.
Jin C; Sunshine Lake Pharma Co. Ltd., Shenzhen, 518000, PR China; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, PR China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Nov 05; Vol. 223, pp. 113644. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Antidepressive Agents/*chemistry
Pyridones/*chemistry
Serotonin Uptake Inhibitors/*chemical synthesis
Animals ; Antidepressive Agents/metabolism ; Antidepressive Agents/pharmacology ; Drug Stability ; Half-Life ; Humans ; Hypothalamus/drug effects ; Hypothalamus/metabolism ; Maze Learning/drug effects ; Microsomes, Liver/metabolism ; Piperazine/chemistry ; Pyridones/metabolism ; Pyridones/pharmacology ; Rats ; Rats, Sprague-Dawley ; Serotonin/metabolism ; Serotonin Uptake Inhibitors/metabolism ; Serotonin Uptake Inhibitors/pharmacology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress.
Autorzy :
Ito T; Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan.
Hiramatsu Y; Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan.
Mouri A; Department of Regulatory Science for Evaluation & Development of Pharmaceuticals and Devices, Graduate School of Health Science, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Yoshigai T; Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan.
Takahashi A; Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan.
Yoshimi A; Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan.
Mamiya T; Department of Chemical Pharmacology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan.
Ozaki N; Department of Psychiatry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8560, Japan.
Noda Y; Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan; Department of Psychiatry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8560, Japan. Electronic address: .
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Źródło :
Neuroscience research [Neurosci Res] 2021 Oct; Vol. 171, pp. 83-91. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Serotonin*/metabolism
Protein Kinase C beta/*metabolism
Serotonin Plasma Membrane Transport Proteins/*metabolism
Stress, Psychological/*metabolism
Animals ; Mice ; Phosphorylation ; Swimming
Czasopismo naukowe
Tytuł :
Drug design of new 5-HT 6 R antagonists aided by artificial neural networks.
Autorzy :
da Silva AP; Departamento de Química e Física Molecular, Instituto de Química de São Carlos, Universidade de São Paulo, C.P 780, 13560-970, São Carlos, SP, Brazil.
Chiari LPA; Departamento de Química e Física Molecular, Instituto de Química de São Carlos, Universidade de São Paulo, C.P 780, 13560-970, São Carlos, SP, Brazil.
Guimaraes AR; Departamento de Química e Física Molecular, Instituto de Química de São Carlos, Universidade de São Paulo, C.P 780, 13560-970, São Carlos, SP, Brazil.
Honorio KM; Escola de Artes, Ciência e Humanidades, Universidade de São Paulo, São Paulo, 03828-000, Brazil.
da Silva ABF; Departamento de Química e Física Molecular, Instituto de Química de São Carlos, Universidade de São Paulo, C.P 780, 13560-970, São Carlos, SP, Brazil. Electronic address: .
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Źródło :
Journal of molecular graphics & modelling [J Mol Graph Model] 2021 May; Vol. 104, pp. 107844. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Design*
Serotonin*
Humans ; Neural Networks, Computer ; Receptors, Serotonin ; Serotonin Antagonists/pharmacology
Czasopismo naukowe
Tytuł :
Effectiveness of Vortioxetine on Emotional Blunting in Patients with Major Depressive Disorder with inadequate response to SSRI/SNRI treatment.
Autorzy :
Fagiolini A; Division of Psychiatry, Department of Molecular and Developmental Medicine, University of Siena School of Medicine, Italy.
Florea I; H. Lundbeck A/S, Valby, Denmark.
Loft H; H. Lundbeck A/S, Valby, Denmark.
Christensen MC; H. Lundbeck A/S, Valby, Denmark. Electronic address: .
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Źródło :
Journal of affective disorders [J Affect Disord] 2021 Mar 15; Vol. 283, pp. 472-479. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Depressive Disorder, Major*/drug therapy
Serotonin and Noradrenaline Reuptake Inhibitors*/pharmacology
Serotonin and Noradrenaline Reuptake Inhibitors*/therapeutic use
Double-Blind Method ; Humans ; Serotonin Uptake Inhibitors/pharmacology ; Serotonin Uptake Inhibitors/therapeutic use ; Treatment Outcome ; Vortioxetine
Czasopismo naukowe
Tytuł :
Serotonin system gene variants and regional brain volume differences in pediatric OCD.
Autorzy :
Sinopoli VM; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Erdman L; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Computer Science, University of Toronto, Toronto, ON, Canada.
Burton CL; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada.
Easter P; Department of Psychiatry, Wayne State University School of Medicine, Detroit, MI, USA.
Rajendram R; Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Baldwin G; Department of Psychiatry, Wayne State University School of Medicine, Detroit, MI, USA.
Peterman K; Department of Psychiatry, Wayne State University School of Medicine, Detroit, MI, USA.
Coste J; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Shaheen SM; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, 4th floor, Teaching, Research and Wellness (TRW) Building, 3280 Hospital Dr NW, Calgary, AB, T2N 4Z6, ON, Canada.
Hanna GL; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Rosenberg DR; Department of Psychiatry, Wayne State University School of Medicine, Detroit, MI, USA.
Arnold PD; Program in Genetics & Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada. .; Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, 4th floor, Teaching, Research and Wellness (TRW) Building, 3280 Hospital Dr NW, Calgary, AB, T2N 4Z6, ON, Canada. .; Departments of Psychiatry and Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, ON, Canada. .
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Źródło :
Brain imaging and behavior [Brain Imaging Behav] 2020 Oct; Vol. 14 (5), pp. 1612-1625.
Typ publikacji :
Journal Article
MeSH Terms :
Obsessive-Compulsive Disorder*/diagnostic imaging
Obsessive-Compulsive Disorder*/genetics
Serotonin*
Receptor, Serotonin, 5-HT2C/*genetics
Brain/diagnostic imaging ; Child ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Polymorphism, Single Nucleotide/genetics ; Serotonin Plasma Membrane Transport Proteins
Czasopismo naukowe
Tytuł :
Depressive Symptoms are Associated with low Serotonin Levels in Plasma but are not 5-HTTLPR Genotype Dependent in Older Adults.
Autorzy :
Trujillo-Hernández PE; Universidad Autónoma de Coahuila (Mexico).
Sáenz-Galindo A; Universidad Autónoma de Coahuila (Mexico).
Saucedo-Cárdenas O; Universidad Autónoma de Nuevo León (Mexico).
Villarreal-Reyna MLÁ; Universidad Autónoma de Coahuila (Mexico).
Salinas-Santander MA; Universidad Autónoma de Coahuila (Mexico).
Carrillo-Cervantes AL; Universidad Autónoma de Coahuila (Mexico).
Torres-Obregón R; Universidad Autónoma de Coahuila (Mexico).
Esparza-González SC; Universidad Autónoma de Coahuila (Mexico).
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Źródło :
The Spanish journal of psychology [Span J Psychol] 2021 Apr 30; Vol. 24, pp. e28. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
Depression*/genetics
Serotonin*
Aged ; Genotype ; Humans ; Polymorphism, Genetic ; Serotonin Plasma Membrane Transport Proteins/genetics
Czasopismo naukowe

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