Temat: "serotonin" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The role of vitamin D in depression and anxiety disorders: a review of the literature.
Autorzy:: Renteria K; Nutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX, USA.
Nguyen H; Nutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX, USA.
Koh GY; Nutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX, USA.; Pokaż więcej
Źródło:: Nutritional neuroscience [Nutr Neurosci] 2024 Mar; Vol. 27 (3), pp. 262-270. Date of Electronic Publication: 2023 Mar 06.
Typ publikacji:: Review; Journal Article
MeSH Terms:: Depression*/microbiology
Vitamin D*/therapeutic use
Animals ; Humans ; Serotonin ; Anxiety Disorders/drug therapy ; Anxiety ; Vitamins

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Skocz do pozycji: 2.

Tytuł:: Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population.
Autorzy:: Simonyte S; Institute of Cardiology of Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania. .
Grabauskyte I; Department of Physics, Mathematics and Biophysics of Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Macijauskiene J; Department of Geriatrics of Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lesauskaite V; Department of Geriatrics of Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lesauskaite V; Institute of Cardiology of Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Kvaal KS; Faculty of Social and Health Sciences, Inland Norway University of Applied Sciences, Lillehammer, Innlandet, Norway.
Stewart R; King's College London (Institute of Psychiatry, Psychology and Neuroscience), London, UK.; South London and Maudsley NHS Foundation Trust, London, UK.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 09; Vol. 13 (1), pp. 12920. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Serotonin Plasma Membrane Transport Proteins*/genetics
Depression*/epidemiology
Depression*/genetics
Aged ; Humans ; Lithuania/epidemiology ; Life Change Events ; Polymorphism, Genetic ; Genotype ; Alleles

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Skocz do pozycji: 3.

Tytuł:: The potential beneficial effects of Lactobacillus plantarum GM11 on rats with chronic unpredictable mild stress- induced depression.
Autorzy:: Ma J; Department of Research and Development, Weichuang Tianyi Biotechnology Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Wang J; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Department of Orthopaedics, Chengdu Second People's Hospital, Chengdu, Sichuan, People's Republic of China.
Wang G; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Wan Y; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Li N; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Luo L; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Gou H; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Gu J; Department of Neurosurgery, PLA Strategic Support Force Characteristic Medical Center, Beijing, People's Republic of China.; Pokaż więcej
Źródło:: Nutritional neuroscience [Nutr Neurosci] 2024 May; Vol. 27 (5), pp. 413-424. Date of Electronic Publication: 2023 Apr 28.
Typ publikacji:: Journal Article
MeSH Terms:: Depression*/drug therapy
Depression*/etiology
Depression*/metabolism
Lactobacillus plantarum*
Rats ; Male ; Animals ; Antidepressive Agents/therapeutic use ; Antidepressive Agents/pharmacology ; Brain-Derived Neurotrophic Factor/genetics ; Brain-Derived Neurotrophic Factor/metabolism ; Hypothalamo-Hypophyseal System ; Rats, Sprague-Dawley ; Pituitary-Adrenal System ; Hippocampus/metabolism ; Serotonin/metabolism ; Neurotransmitter Agents/metabolism ; RNA, Messenger/metabolism ; Stress, Psychological/psychology ; Disease Models, Animal

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Skocz do pozycji: 4.

Tytuł:: Effects of the Combination of the C1473G Mutation in the Tph2 Gene and Lethal Yellow Mutations in the Raly-Agouti Locus on Behavior, Brain 5-HT and Melanocortin Systems in Mice.
Autorzy:: Komleva PD; Department of Psychoneuropharmacology, Federal Research Center Institute of Cytology and Genetic Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Alhalabi G; Department of Genetic Collections of Neural Disorders, Federal Research Center Institute of Cytology and Genetic Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Izyurov AE; Department of Genetics of Industrial Microorganisms, Federal Research Center Institute of Cytology and Genetic Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Khotskin NV; Department of Genetic Collections of Neural Disorders, Federal Research Center Institute of Cytology and Genetic Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Kulikov AV; Department of Genetic Collections of Neural Disorders, Federal Research Center Institute of Cytology and Genetic Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Jun 08; Vol. 13 (6). Date of Electronic Publication: 2023 Jun 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain*/metabolism
Depression*/etiology
Depression*/genetics
Depression*/metabolism
Obesity*/etiology
Obesity*/genetics
Obesity*/metabolism
Serotonin*/genetics
Serotonin*/metabolism
Tryptophan Hydroxylase*/genetics
Tryptophan Hydroxylase*/metabolism
Melanocortins*/genetics
Melanocortins*/metabolism
Animals ; Mice ; Mutation ; Swimming

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Skocz do pozycji: 5.

Tytuł:: Possible psychedelic therapeutic mechanism.
Autorzy:: Hess EM; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Gould TD; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.; Baltimore Veterans Affairs Medical Center, Veterans Affairs Maryland Health Care System, Baltimore, MD, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2023 Feb 17; Vol. 379 (6633), pp. 642-643. Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Hallucinogens*/pharmacology
Hallucinogens*/therapeutic use
N,N-Dimethyltryptamine*/pharmacology
N,N-Dimethyltryptamine*/therapeutic use
Receptor, Serotonin, 5-HT2A*/metabolism
Serotonin*/metabolism
Serotonin*/pharmacology
Serotonin 5-HT2 Receptor Agonists*/pharmacology
Serotonin 5-HT2 Receptor Agonists*/therapeutic use
Depression*/drug therapy
Humans ; Animals

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Skocz do pozycji: 6.

Tytuł:: Electroacupuncture alleviated depression-like behaviors in ventromedial prefrontal cortex of chronic unpredictable mild stress-induced rats: Increasing synaptic transmission and phosphorylating dopamine transporter.
Autorzy:: Cai X; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wu M; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zhang Z; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Liu H; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Huang S; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Song J; Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Key Laboratory of Mental Health of the Ministry of Education, Guangdong Province Key Laboratory of Psychiatric Disorders, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Ren S; Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Key Laboratory of Mental Health of the Ministry of Education, Guangdong Province Key Laboratory of Psychiatric Disorders, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Huang Y; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Sep; Vol. 29 (9), pp. 2608-2620. Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Depression*/drug therapy
Electroacupuncture*
Rats ; Male ; Animals ; Rats, Sprague-Dawley ; Dopamine Plasma Membrane Transport Proteins/metabolism ; Hippocampus/metabolism ; Antidepressive Agents ; Synaptic Transmission ; Selective Serotonin Reuptake Inhibitors/pharmacology ; Selective Serotonin Reuptake Inhibitors/therapeutic use ; Prefrontal Cortex/metabolism ; Disease Models, Animal

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Skocz do pozycji: 7.

Tytuł:: Is the serotonin hypothesis/theory of depression still relevant? Methodological reflections motivated by a recently published umbrella review.
Autorzy:: Möller HJ; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany. .
Falkai P; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany.; Pokaż więcej
Źródło:: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2023 Feb; Vol. 273 (1), pp. 1-3.
Typ publikacji:: Editorial; Comment
MeSH Terms:: Depression*
Serotonin*
Humans ; Review Literature as Topic

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Skocz do pozycji: 8.

Tytuł:: Overcoming Depression with 5-HT 2A Receptor Ligands.
Autorzy:: Zięba A; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Stępnicki P; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Matosiuk D; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Kaczor AA; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.; School of Pharmacy, University of Eastern Finland, Yliopistonranta 1, P.O. Box 1627, FI-70211 Kuopio, Finland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 21; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 21.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antidepressive Agents/*chemistry
Depression/*metabolism
Receptor, Serotonin, 5-HT2A/*chemistry
Receptor, Serotonin, 5-HT2A/*metabolism
Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Depression/drug therapy ; Drug Design ; Humans ; Ligands ; Models, Molecular ; Protein Conformation ; Serotonin 5-HT2 Receptor Agonists/chemistry ; Serotonin 5-HT2 Receptor Agonists/pharmacology ; Serotonin 5-HT2 Receptor Agonists/therapeutic use ; Serotonin 5-HT2 Receptor Antagonists/chemistry ; Serotonin 5-HT2 Receptor Antagonists/pharmacology ; Serotonin 5-HT2 Receptor Antagonists/therapeutic use ; Structure-Activity Relationship

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Skocz do pozycji: 9.

Tytuł:: 5-HT Receptors and the Development of New Antidepressants.
Autorzy:: Ślifirski G; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097 Warsaw, Poland.
Król M; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097 Warsaw, Poland.
Turło J; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 20; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antidepressive Agents/*therapeutic use
Depression/*drug therapy
Receptors, Serotonin/*metabolism
Brain/metabolism ; Drug Development/trends ; Humans ; Receptors, Serotonin/drug effects ; Serotonergic Neurons/drug effects ; Serotonergic Neurons/metabolism ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins/metabolism

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Skocz do pozycji: 10.

Tytuł:: Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms.
Autorzy:: Biney RP; Department of Pharmacology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana. .; School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Cape Coast, Ghana. .
Benneh CK; Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.
Adongo DW; Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.
Ameyaw EO; School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Cape Coast, Ghana.
Woode E; Department of Pharmacology and Toxicology, School of Pharmacy, University of Health and Allied Sciences, Ho, Ghana.; Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2021 Aug; Vol. 238 (8), pp. 2105-2120. Date of Electronic Publication: 2021 Apr 10.
Typ publikacji:: Journal Article
MeSH Terms:: Antidepressive Agents/*therapeutic use
Brain/*drug effects
Brain/*metabolism
Depression/*drug therapy
Diterpenes, Kaurane/*therapeutic use
Serotonin/*metabolism
Animals ; Antidepressive Agents/pharmacology ; Depression/metabolism ; Depression/psychology ; Diterpenes, Kaurane/pharmacology ; Dose-Response Relationship, Drug ; Hindlimb Suspension/adverse effects ; Hindlimb Suspension/psychology ; Male ; Mice ; Mice, Inbred ICR ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Organ Culture Techniques ; Rats ; Rats, Sprague-Dawley ; Serotonin Antagonists/pharmacology ; Serotonin Antagonists/therapeutic use ; Swimming/psychology ; Zebrafish

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Skocz do pozycji: 11.

Tytuł:: Correlation between intestinal microbiotal imbalance and 5-HT metabolism, immune inflammation in chronic unpredictable mild stress male rats.
Autorzy:: Li H; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Wang P; Department of Urology, Qingdao Municipal Hospital, Qingdao University, Qingdao, Shandong Province, China.
Zhou Y; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Zhao F; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Gao X; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Wu C; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Wu T; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Jiang L; School of Nursing, Qingdao University, Qingdao, Shandong Province, China.
Zhang D; Center of Colon and Rectum, Qingdao Municipal Hospital, Qingdao University, Qingdao, Shandong Province, China.; Pokaż więcej
Źródło:: Genes, brain, and behavior [Genes Brain Behav] 2022 Jul; Vol. 21 (6), pp. e12806. Date of Electronic Publication: 2022 May 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Depression*/metabolism
Serotonin*/metabolism
Animals ; Behavior, Animal ; Cytokines/metabolism ; Disease Models, Animal ; Hippocampus/metabolism ; Inflammation/metabolism ; Male ; RNA, Ribosomal, 16S/metabolism ; Rats ; Rats, Wistar ; Stress, Psychological/metabolism

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Skocz do pozycji: 12.

Tytuł:: Involvement of the serotonergic system in the antidepressant-like effect of 1-(phenylselanyl)-2-(p-tolyl)indolizine in mice.
Autorzy:: da Rocha MJ; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Pires CS; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Presa MH; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Besckow EM; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Nunes GD; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Gomes CS; Clean Organic Synthesis Laboratory (LASOL), Postgraduate Program in Chemistry (PPGQ), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Penteado F; Clean Organic Synthesis Laboratory (LASOL), Postgraduate Program in Chemistry (PPGQ), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Lenardão EJ; Clean Organic Synthesis Laboratory (LASOL), Postgraduate Program in Chemistry (PPGQ), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil.
Bortolatto CF; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil. .
Brüning CA; Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Postgraduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences (CCQFA), Federal University of Pelotas (UFPel), Capão Do Leão Campus, Pelotas, RS, 96010-900, Brazil. .; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2023 Feb; Vol. 240 (2), pp. 373-389. Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:: Journal Article
MeSH Terms:: Depression*/drug therapy
Depression*/metabolism
Indolizines*/pharmacology
Male ; Female ; Animals ; Mice ; Serotonin/metabolism ; Molecular Docking Simulation ; Motor Activity ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Swimming ; Hindlimb Suspension

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Skocz do pozycji: 13.

Tytuł:: Design, Sustainable Synthesis and Biological Evaluation of a Novel Dual α2A/5-HT7 Receptor Antagonist with Antidepressant-Like Properties.
Autorzy:: Canale V; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Kotańska M; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Dziubina A; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Stefaniak M; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Siwek A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Starowicz G; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Marciniec K; Department of Organic Chemistry, Medical University of Silesia, 41-200 Sosnowiec, Poland.
Kasza P; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Satała G; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Kraków, Poland.
Duszyńska B; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Kraków, Poland.
Bantreil X; IBMM, Université de Montpellier, CNRS, ENSCM, 34095 Montpellier, France.
Lamaty F; IBMM, Université de Montpellier, CNRS, ENSCM, 34095 Montpellier, France.
Bednarski M; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Sapa J; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.
Zajdel P; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Kraków, Poland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jun 23; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 23.
Typ publikacji:: Journal Article
MeSH Terms:: Adrenergic alpha-2 Receptor Antagonists/*chemistry
Adrenergic alpha-2 Receptor Antagonists/*pharmacology
Antidepressive Agents/*pharmacology
Depression/*drug therapy
Motor Activity/*drug effects
Receptors, Adrenergic, alpha-2/*metabolism
Receptors, Serotonin/*metabolism
Adrenergic alpha-2 Receptor Antagonists/chemical synthesis ; Adrenergic alpha-2 Receptor Antagonists/therapeutic use ; Animals ; Antidepressive Agents/therapeutic use ; Behavior Rating Scale ; Depression/physiopathology ; HEK293 Cells ; Humans ; Ligands ; Male ; Mice ; Mirtazapine/pharmacology ; Mirtazapine/therapeutic use ; Norepinephrine/metabolism ; Piperidines/chemistry ; Rats ; Receptors, Serotonin/genetics ; Serotonin/metabolism ; Swimming

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Skocz do pozycji: 14.

Tytuł:: Mechanism and therapeutic strategies of depression after myocardial infarction.
Autorzy:: Yang Y; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China.
Li X; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China.
Chen S; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China.
Xiao M; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China.
Liu Z; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China.
Li J; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China. .
Cheng Y; Guangdong Key Laboratory for Translational Cancer Research of Chinese Medicine, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, International Institute for Translational Chinese Medicine, School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, China. .; Pokaż więcej
Źródło:: Psychopharmacology [Psychopharmacology (Berl)] 2021 Jun; Vol. 238 (6), pp. 1401-1415. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Depression/*drug therapy
Myocardial Infarction/*complications
Selective Serotonin Reuptake Inhibitors/*administration & dosage
Gastrointestinal Microbiome/physiology ; Humans ; Hypothalamo-Hypophyseal System/metabolism ; Pituitary-Adrenal System/metabolism ; Serotonin/metabolism ; Selective Serotonin Reuptake Inhibitors/pharmacology

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Skocz do pozycji: 15.

Tytuł:: HTR1A, TPH2, and 5-HTTLPR Polymorphisms and Their Impact on the Severity of Depressive Symptoms and on the Concentration of Tryptophan Catabolites during Hepatitis C Treatment with Pegylated Interferon-α2a and Oral Ribavirin (PEG-IFN-α2a/RBV).
Autorzy:: Pawlowski T; Department of Psychiatry, Wrocław Medical University, 50-367 Wrocław, Poland.
Malyszczak K; Department of Psychiatry, Wrocław Medical University, 50-367 Wrocław, Poland.
Pawlak D; Department of Pharmacodynamics, Medical University of Bialystok, 15-089 Białystok, Poland.
Inglot M; Department of Infectious Diseases, Liver Diseases and Acquired Immune Deficiency, Wroclaw Medical University, 50-367 Wrocław, Poland.
Zalewska M; Department of Infectious Diseases, Liver Diseases and Acquired Immune Deficiency, Wroclaw Medical University, 50-367 Wrocław, Poland.
Grzywacz A; Independent Laboratory of Health Promotion, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
Radkowski M; Department of Immunopathology of Infectious and Parasitic Diseases, Medical University of Warsaw, 02-091 Warsaw, Poland.
Laskus T; Department of Adult Infectious Diseases, Medical University of Warsaw, 02-091 Warsaw, Poland.
Janocha-Litwin J; Department of Infectious Diseases and Hepatology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Frydecka D; Department of Psychiatry, Wrocław Medical University, 50-367 Wrocław, Poland.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Mar 22; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Depression*/genetics
Depression*/metabolism
Hepatitis C, Chronic*/complications
Hepatitis C, Chronic*/drug therapy
Hepatitis C, Chronic*/genetics
Interferon alpha-2*/adverse effects
Interferon alpha-2*/pharmacology
Interferon alpha-2*/therapeutic use
Tryptophan*/drug effects
Tryptophan*/metabolism
Adult ; Humans ; Antiviral Agents/therapeutic use ; Kynurenine ; Polyethylene Glycols/pharmacology ; Polymorphism, Genetic ; Prospective Studies ; Receptor, Serotonin, 5-HT1A/genetics ; Ribavirin/adverse effects ; Ribavirin/pharmacology ; Ribavirin/therapeutic use ; Tryptophan Hydroxylase/genetics ; Tryptophan Oxygenase/genetics

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Skocz do pozycji: 16.

Tytuł:: Association of HTR3B gene polymorphisms with depression and its executive dysfunction: a case-control study.
Autorzy:: Wang L; Department of Psychology, Shandong Normal University, Jinan, 250358, Shandong, China.; Department of Psychiatry, Shandong Mental Health Center, Shandong University, Jinan, 250014, Shandong, China.
Wang M; School of Mental Health, Jining Medical University, Jining, 272000, Shandong, China.
Zhao C; School of Mental Health, Jining Medical University, Jining, 272000, Shandong, China.
Jian J; Department of Psychiatry, Shandong Mental Health Center, Shandong University, Jinan, 250014, Shandong, China.
Qiao D; Department of Psychiatry, Shandong Mental Health Center, Shandong University, Jinan, 250014, Shandong, China. .; Pokaż więcej
Źródło:: BMC psychiatry [BMC Psychiatry] 2023 Feb 27; Vol. 23 (1), pp. 128. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Depression*/genetics
Cognitive Dysfunction*
Humans ; Case-Control Studies ; Polymorphism, Single Nucleotide ; Genotype ; Receptors, Serotonin, 5-HT3/genetics

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Skocz do pozycji: 17.

Tytuł:: Indoleamine 2, 3-dioxygenase is responsible for low stress tolerance after intracerebral hemorrhage.
Autorzy:: Ohnishi M; Department of Pharmacotherapeutics, Graduate School of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Akagi M; Department of Pharmacotherapeutics, Graduate School of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Kotsuki M; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Yonemura S; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Aokawa H; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Yamashita-Ibara M; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Yokofujita O; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Maehara S; Department of Physical Chemistry for Bioactive Molecules, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Hata T; Department of Physical Chemistry for Bioactive Molecules, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Inoue A; Department of Pharmacotherapeutics, Graduate School of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.; Department of Pharmacotherapeutics, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Feb 08; Vol. 18 (2), pp. e0273037. Date of Electronic Publication: 2023 Feb 08 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Kynurenine*/metabolism
Depression*/drug therapy
Mice ; Animals ; Serotonin/metabolism ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Cerebral Hemorrhage

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Skocz do pozycji: 18.

Tytuł:: The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects.
Autorzy:: Borroto-Escuela DO; Department of Neuroscience, Karolinska Institutet, Biomedicum, Lab B0851, Solnavägen 9, 17 177 Stockholm, Sweden.; Department of Biomolecular Science, Section of Morphology, Physiology and Environmental Biology, University of Urbino, Campus Scientifico Enrico Mattei, via Ca' le Suore 2, I-61029 Urbino, Italy.; Observatorio Cubano de Neurociencias, Grupo Bohío-Estudio, Zayas 50, 62100 Yaguajay, Cuba.
Ambrogini P; Department of Biomolecular Science, Section of Morphology, Physiology and Environmental Biology, University of Urbino, Campus Scientifico Enrico Mattei, via Ca' le Suore 2, I-61029 Urbino, Italy.
Chruścicka B; APC Microbiome Ireland, University College Cork, T12K8AF Cork, Ireland.; Małopolska Centre of Biotechnology, Jagiellonian University, 30 252 Kraków, Poland.
Lindskog M; Department of Neuroscience, University of Uppsala, 75 105 Uppsala, Sweden.
Crespo-Ramirez M; Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Hernández-Mondragón JC; Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Perez de la Mora M; Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Schellekens H; APC Microbiome Ireland, University College Cork, T12K8AF Cork, Ireland.; Department of Anatomy and Neuroscience, University College Cork, T12K8AF Cork, Ireland.
Fuxe K; Department of Neuroscience, Karolinska Institutet, Biomedicum, Lab B0851, Solnavägen 9, 17 177 Stockholm, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 15; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Signal Transduction*
Depression/*metabolism
Depressive Disorder, Major/*metabolism
Hippocampus/*metabolism
Neurons/*metabolism
Serotonin/*metabolism
Animals ; Humans ; Receptor, Fibroblast Growth Factor, Type 1/metabolism ; Receptor, Serotonin, 5-HT1A/metabolism ; Receptor, Serotonin, 5-HT2A/metabolism ; Receptor, Serotonin, 5-HT2C/metabolism ; Receptors, Oxytocin/metabolism

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Skocz do pozycji: 19.

Tytuł:: Association between child maltreatment and depressive symptoms in emerging adulthood: The mediating and moderating roles of DNA methylation.
Autorzy:: Comtois-Cabana M; Department of Psychology, University of Montreal, Montreal, Quebec, Canada.; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Barr E; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Provençal N; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Ouellet-Morin I; School of Criminology, University of Montreal, Montreal, Quebec, Canada.; Research Center of the Montreal Mental Health University Institute, Montreal, Quebec, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jan 12; Vol. 18 (1), pp. e0280203. Date of Electronic Publication: 2023 Jan 12 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Depression*/genetics
Child Abuse*
Adult ; Child ; Humans ; Male ; Adolescent ; Young Adult ; DNA Methylation ; Retrospective Studies ; Prospective Studies ; Serotonin Plasma Membrane Transport Proteins/genetics

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Skocz do pozycji: 20.

Tytuł:: Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Autorzy:: Meng P; Hunan University of Chinese Medicine, Changsha, Hunan, China.; Hunan Key Laboratory of Traditional Chinese Medicine Prevention & Treatment of Depressive Diseases, Changsha, Hunan, China.
Zhang X; Hunan University of Chinese Medicine, Changsha, Hunan, China.; The Second People's Hospital of Hunan Province, Changsha, Hunan, China.
Li D; Hunan University of Chinese Medicine, Changsha, Hunan, China.
Yang H; Hunan Key Laboratory of Traditional Chinese Medicine Prevention & Treatment of Depressive Diseases, Changsha, Hunan, China.; The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Lin X; Hunan Key Laboratory of Traditional Chinese Medicine Prevention & Treatment of Depressive Diseases, Changsha, Hunan, China.; The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Zhao H; Hunan University of Chinese Medicine, Changsha, Hunan, China.; Hunan Key Laboratory of Traditional Chinese Medicine Prevention & Treatment of Depressive Diseases, Changsha, Hunan, China.
Li P; Hunan University of Chinese Medicine, Changsha, Hunan, China.
Wang Y; Hunan University of Chinese Medicine, Changsha, Hunan, China.; Hunan Key Laboratory of Traditional Chinese Medicine Prevention & Treatment of Depressive Diseases, Changsha, Hunan, China.
Wang X; The Second People's Hospital of Hunan Province, Changsha, Hunan, China.
Ge J; Hunan Academy of Chinese Medicine, Changsha, Hunan, China.; Pokaż więcej
Źródło:: Neural plasticity [Neural Plast] 2023 Jan 07; Vol. 2023, pp. 1455634. Date of Electronic Publication: 2023 Jan 07 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Depression*/metabolism
Gastrointestinal Microbiome*
Rats ; Animals ; Brain-Derived Neurotrophic Factor/metabolism ; Serotonin/metabolism ; Bromodeoxyuridine/metabolism ; Nerve Regeneration ; Homeostasis ; Signal Transduction ; Hippocampus/metabolism ; Body Weight ; Stress, Psychological/metabolism ; Disease Models, Animal

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