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Tytuł:
Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir.
Autorzy:
Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Okoye AA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Fennessey CM; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Varco-Merth B; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Immonen TT; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Kose E; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Conchas A; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Pinkevych M; Infection Analytics Program, Kirby Institute for Infection and Immunity, University of New South Wales, Sydney, Australia.
Lipkey L; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Newman L; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Macairan A; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Bosche M; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Bosche WJ; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Berkemeier B; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Fast R; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Hull M; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Oswald K; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Shoemaker R; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Silipino L; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Gorelick RJ; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Duell D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Marenco A; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Brantley W; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Smedley J; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Axthelm M; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
Davenport MP; Infection Analytics Program, Kirby Institute for Infection and Immunity, University of New South Wales, Sydney, Australia.
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Apr 09; Vol. 20 (4), pp. e1012135. Date of Electronic Publication: 2024 Apr 09 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*/drug therapy
Simian Immunodeficiency Virus*/physiology
HIV Infections*/drug therapy
Animals ; Macaca mulatta ; Virus Replication ; Anti-Retroviral Agents/therapeutic use ; Anti-Retroviral Agents/pharmacology ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIHISIV: a database of gene expression in HIV and SIV host immune response.
Autorzy:
Costa RL; DEXL Lab, National Laboratory for Scientific Computing, Petrópolis, Brazil. .
Gadelha L; German Human Genome-Phenome Archive (GHGA, W620), German Cancer Research Center (DKFZ), Heidelberg, Germany. .
D'arc M; Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ribeiro-Alves M; Instituto Nacional de Infectologia Evandro Chagas, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Robertson DL; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK.
Schwartz JM; Division of Evolution, Infection and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK.
Soares MA; Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.; Programa de Oncovirologia, Divisão de Pesquisa Translacional, Instituto Nacional do Câncer, Rio de Janeiro, 20230-130, Brazil.
Porto F; DEXL Lab, National Laboratory for Scientific Computing, Petrópolis, Brazil.
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2024 Mar 22; Vol. 25 (1), pp. 125. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Simian Immunodeficiency Virus*/genetics
Simian Acquired Immunodeficiency Syndrome*/genetics
HIV Infections*
Animals ; Humans ; HIV ; Disease Progression ; Immunity ; Gene Expression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.
Autorzy:
Lim SY; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Lee J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Osuna CE; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Vikhe P; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Schalk DR; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Chen E; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Fray E; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Kumar M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Schultz-Darken N; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Rakasz E; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Capuano S; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Ladd RA; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Gil HM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Evans DT; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA.
Jeng EK; Altor Biosciences, Miramar, FL 33027, USA.
Seaman M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Martin M; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Van Dorp C; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Perelson AS; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; Santa Fe Institute, Santa Fe, NM 87501, USA.
Wong HC; Altor Biosciences, Miramar, FL 33027, USA.
Siliciano JD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Siliciano R; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Safrit JT; ImmunityBio, Culver City, CA 90232, USA.
Nixon DF; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Soon-Shiong P; ImmunityBio, Culver City, CA 90232, USA.
Nussenzweig M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.
Whitney JB; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 08; Vol. 383 (6687), pp. 1104-1111. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Retroviral Agents*/therapeutic use
Anti-Retroviral Agents*/pharmacology
Simian Acquired Immunodeficiency Syndrome*/drug therapy
Simian Acquired Immunodeficiency Syndrome*/therapy
Simian Immunodeficiency Virus*
Recombinant Fusion Proteins*/administration & dosage
Recombinant Fusion Proteins*/pharmacology
Animals ; Humans ; Broadly Neutralizing Antibodies/administration & dosage ; CD8-Positive T-Lymphocytes/virology ; Immunotherapy ; Macaca mulatta ; Viral Load ; Remission Induction ; Drug Therapy, Combination
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Alcohol Impairs Bioenergetics and Differentiation Capacity of Myoblasts from Simian Immunodeficiency Virus-Infected Female Macaques.
Autorzy:
Levitt DE; Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX 79409, USA.
Bourgeois BL; Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Rodríguez-Graciani KM; Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Molina PE; Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Simon L; Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.; Comprehensive Alcohol-HIV/AIDS Research Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 19; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Simian Immunodeficiency Virus*
Simian Acquired Immunodeficiency Syndrome*/complications
Binge Drinking*
Muscular Diseases*/complications
Female ; Animals ; Male ; Macaca mulatta ; Reactive Oxygen Species ; Ethanol/pharmacology ; Myoblasts ; Energy Metabolism ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SIV Infection Is Associated with Transient Acute-Phase Steatosis in Hepatocytes In Vivo.
Autorzy:
Derby N; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Biswas S; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Yusova S; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Luevano-Santos C; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Pacheco MC; Department of Laboratories, Seattle Children's Hospital, Seattle, WA 98105, USA.
Meyer KA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Johnson BI; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Fischer M; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Fancher KA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Fisher C; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Abraham YM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
McMahon CJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Lutz SS; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Smedley JV; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR 97006, USA.; Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Sodora DL; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
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Źródło:
Viruses [Viruses] 2024 Feb 15; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*/drug therapy
Simian Immunodeficiency Virus*
HIV Infections*/complications
Fatty Liver*
Animals ; Humans ; Macaca mulatta ; Hepatocytes/metabolism ; DNA ; Cholesterol
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Editorial Note: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission.
Corporate Authors:
PLOS ONE Editors
Źródło:
PloS one [PLoS One] 2024 Feb 12; Vol. 19 (2), pp. e0298985. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*/transmission
Simian Immunodeficiency Virus*
HIV Infections*/transmission
Animals ; Primates
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection.
Autorzy:
Wilk AJ; Stanford Immunology Program, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Medical Scientist Training Program, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Marceau JO; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Kazer SW; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Fleming I; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Miao VN; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, MA, 02115, USA.
Galvez-Reyes J; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Kimata JT; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Shalek AK; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Holmes S; Department of Statistics, Stanford University, Stanford, CA, 94305, USA.
Overbaugh J; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Blish CA; Stanford Immunology Program, Stanford University School of Medicine, Stanford, CA, 94305, USA. .; Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA. .; Medical Scientist Training Program, Stanford University School of Medicine, Stanford, CA, 94305, USA. .; Chan Zuckerberg Biohub, San Francisco, CA, 94158, USA. .
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Źródło:
Genome medicine [Genome Med] 2024 Feb 05; Vol. 16 (1), pp. 24. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*
Simian Immunodeficiency Virus*/genetics
Lentivirus Infections*
Animals ; Humans ; Feedback ; Disease Progression ; Immunity ; Interferons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Macrophages: Key Cellular Players in HIV Infection and Pathogenesis.
Autorzy:
Woottum M; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
Yan S; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
Sayettat S; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
Grinberg S; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Cathelin D; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Bekaddour N; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Herbeuval JP; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Benichou S; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
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Źródło:
Viruses [Viruses] 2024 Feb 13; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*
Simian Immunodeficiency Virus*
HIV-1*/physiology
HIV Seropositivity*
Humans ; Animals ; Mice ; Macrophages ; Inflammation ; CD4-Positive T-Lymphocytes ; Virus Latency ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.
Autorzy:
Grunst MW; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Gil HM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Grandea AG 3rd; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Snow BJ; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Andrabi R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative Neutralizing Antibody Center, the Collaboration for AIDS Vaccine Discovery (CAVD) and Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.
Nedellec R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative Neutralizing Antibody Center, the Collaboration for AIDS Vaccine Discovery (CAVD) and Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.
Burton I; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative Neutralizing Antibody Center, the Collaboration for AIDS Vaccine Discovery (CAVD) and Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.
Clark NM; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Janaka SK; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Keles NK; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Moriarty RV; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Weiler AM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Capuano S 3rd; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Fennessey CM; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Friedrich TC; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
O'Connor SL; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
O'Connor DH; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Broman AT; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Hangartner L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative Neutralizing Antibody Center, the Collaboration for AIDS Vaccine Discovery (CAVD) and Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.
Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; International AIDS Vaccine Initiative Neutralizing Antibody Center, the Collaboration for AIDS Vaccine Discovery (CAVD) and Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America.; Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America.
Evans DT; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 22; Vol. 20 (1), pp. e1011819. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*
Simian Immunodeficiency Virus*
Animals ; Macaca mulatta ; Antibodies, Viral ; Antibody-Dependent Cell Cytotoxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Deep analysis of CD4 T cells in the rhesus CNS during SIV infection.
Autorzy:
Elizaldi SR; Graduate Group in Immunology, UC Davis, California, United States of America.
Verma A; Department of Pathology, School of Medicine, University of Pittsburgh, Pennsylvania, United States of America.
Ma ZM; California National Primate Research Center, UC Davis, California, United States of America.
Ott S; California National Primate Research Center, UC Davis, California, United States of America.
Rajasundaram D; Department of Pediatrics, School of Medicine, University of Pittsburgh, Pennsylvania, United States of America.
Hawes CE; Graduate Group in Immunology, UC Davis, California, United States of America.
Lakshmanappa YS; California National Primate Research Center, UC Davis, California, United States of America.
Cottrell ML; Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Kashuba ADM; Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Ambrose Z; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pennsylvania, United States of America.
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory, Frederick, Maryland, United States of America.
Morrison JH; California National Primate Research Center, UC Davis, California, United States of America.; Department of Neurology, School of Medicine, UC Davis, California, United States of America.
Iyer SS; Department of Pathology, School of Medicine, University of Pittsburgh, Pennsylvania, United States of America.; California National Primate Research Center, UC Davis, California, United States of America.; Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, UC Davis, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Dec 07; Vol. 19 (12), pp. e1011844. Date of Electronic Publication: 2023 Dec 07 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*
Simian Immunodeficiency Virus*/physiology
HIV Infections*
Animals ; Humans ; CD4-Positive T-Lymphocytes ; Macaca mulatta ; Central Nervous System ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency.
Autorzy:
Docken SS; Infection Analytics Program, Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
McCormick K; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Pampena MB; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Center for AIDS Research and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Samer S; Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
Lindemuth E; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Pinkevych M; Infection Analytics Program, Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
Viox EG; Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
Wu Y; Infection Analytics Program, Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
Schlub TE; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Cromer D; Infection Analytics Program, Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
Paiardini M; Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America.
Betts MR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Center for AIDS Research and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Bar KJ; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Davenport MP; Infection Analytics Program, Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Nov 30; Vol. 19 (11), pp. e1011755. Date of Electronic Publication: 2023 Nov 30 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*
Simian Immunodeficiency Virus*
HIV Infections*
Animals ; Macaca mulatta ; Virus Replication/physiology ; CD8-Positive T-Lymphocytes ; Epitopes ; Viral Load ; Anti-Retroviral Agents/therapeutic use ; Anti-Retroviral Agents/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-21-IgFc immunotherapy alters transcriptional landscape of lymph node cells leading to enhanced flu vaccine response in aging and SIV infection.
Autorzy:
Pallikkuth S; Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida, USA.
Kvistad D; Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida, USA.
Sirupangi T; New Iberia Research Center and Department of Biology, University of Louisiana at Lafayette, New Iberia, Louisiana, USA.
Kizhner A; Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida, USA.
Pahwa R; Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida, USA.
Cameron MJ; Department of Quantitative and Population Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
Richardson B; Department of Quantitative and Population Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
Williams S; Department of Neurology, Onco-Genomics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida, USA.
Ayupe A; Onco-Genomics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida, USA.
Brooks M; Onco-Genomics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida, USA.
Petrovas C; Tissue Analysis Core, Immunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, USA.; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.
Villinger F; New Iberia Research Center and Department of Biology, University of Louisiana at Lafayette, New Iberia, Louisiana, USA.
Pahwa S; Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida, USA.
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Źródło:
Aging cell [Aging Cell] 2023 Nov; Vol. 22 (11), pp. e13984. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Influenza Vaccines*
Simian Acquired Immunodeficiency Syndrome*
Simian Immunodeficiency Virus*/physiology
Humans ; Animals ; T-Lymphocytes, Helper-Inducer ; Macaca mulatta ; Lymph Nodes ; Interleukins/genetics ; Vaccination
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neuroinflammatory Profiling in SIV-Infected Chinese-Origin Rhesus Macaques on Antiretroviral Therapy.
Autorzy:
Solis-Leal A; Host-Pathogen Interaction Program, Texas Biomedical Research Institute, 8715 W Military Dr., San Antonio, TX 78227, USA.
Siddiqui S; Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.
Wu F; Host-Pathogen Interaction Program, Texas Biomedical Research Institute, 8715 W Military Dr., San Antonio, TX 78227, USA.; Tulane Center for Aging, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Mohan M; Host-Pathogen Interaction Program, Texas Biomedical Research Institute, 8715 W Military Dr., San Antonio, TX 78227, USA.
Hu W; Center for Metabolic Disease Research, Department of Pathology and Laboratory Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19122, USA.
Doyle-Meyers LA; Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.
Dufour JP; Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.
Ling B; Host-Pathogen Interaction Program, Texas Biomedical Research Institute, 8715 W Military Dr., San Antonio, TX 78227, USA.; Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.; Tulane Center for Aging, School of Medicine, Tulane University, New Orleans, LA 70112, USA.; Department of Microbiology and Immunology, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
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Źródło:
Viruses [Viruses] 2022 Jan 13; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antiretroviral Therapy, Highly Active*
Simian Immunodeficiency Virus*
Transcriptome*
Macaca mulatta/*virology
Neuroinflammatory Diseases/*genetics
Neuroinflammatory Diseases/*metabolism
Simian Acquired Immunodeficiency Syndrome/*genetics
Simian Acquired Immunodeficiency Syndrome/*metabolism
Animals ; Brain ; Central Nervous System ; Chemokines/metabolism ; China ; Cytokines/metabolism ; Disease Models, Animal ; Gene Expression ; Gene Expression Profiling ; HIV ; HIV Infections/blood ; HIV Infections/genetics ; HIV Infections/metabolism ; Influenza A virus ; Simian Acquired Immunodeficiency Syndrome/blood ; Simian Acquired Immunodeficiency Syndrome/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tocilizumab for treating mevalonate kinase deficiency and TNF receptor-associated periodic syndrome: a case series and literature review.
Autorzy:
Li Y; Department of Rheumatology Immunology and Allergy, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Heath, NO.3333, Bin-sheng Road, 310052, Hangzhou, China.
Lu M; Department of Rheumatology Immunology and Allergy, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Heath, NO.3333, Bin-sheng Road, 310052, Hangzhou, China. .
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Źródło:
Pediatric rheumatology online journal [Pediatr Rheumatol Online J] 2024 Jan 05; Vol. 22 (1), pp. 11. Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Review; Case Reports; Journal Article
MeSH Terms:
Mevalonate Kinase Deficiency*/drug therapy
Simian Acquired Immunodeficiency Syndrome*
Exanthema*/drug therapy
Exanthema*/etiology
Child ; Animals ; Humans ; Interleukin-6 ; Quality of Life ; Tumor Necrosis Factor-alpha ; C-Reactive Protein ; Interleukin-1
SCR Disease Name:
Periodic fever, familial, autosomal dominant
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection.
Autorzy:
Harwood OE; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Matschke LM; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Moriarty RV; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Balgeman AJ; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Weaver AJ; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Ellis-Connell AL; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Weiler AM; Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America.
Winchester LC; College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
Fletcher CV; College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
Friedrich TC; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America.
Keele BF; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
O'Connor DH; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America.
Lang JD; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Center for Human Genomics and Precision Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Reynolds MR; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America.
O'Connor SL; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Sep 25; Vol. 19 (9), pp. e1011676. Date of Electronic Publication: 2023 Sep 25 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*
Simian Immunodeficiency Virus*
HIV Infections*/drug therapy
Humans ; Animals ; Macaca mulatta ; CD8-Positive T-Lymphocytes ; Macaca fascicularis ; Viral Load ; Virus Replication ; Anti-Retroviral Agents/therapeutic use ; Anti-Retroviral Agents/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161 T Cells in SIV-Infected Rhesus Macaques.
Autorzy:
Thirugnanam S; Tulane National Primate Research Center, Covington, LA 70433, USA.
Walker EM; Tulane National Primate Research Center, Covington, LA 70433, USA.
Schiro F; Tulane National Primate Research Center, Covington, LA 70433, USA.
Aye PP; Tulane National Primate Research Center, Covington, LA 70433, USA.
Rappaport J; Tulane National Primate Research Center, Covington, LA 70433, USA.
Rout N; Tulane National Primate Research Center, Covington, LA 70433, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Tulane Center for Aging, Tulane University School of Medicine, New Orleans, LA 70112, USA.
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Źródło:
Viruses [Viruses] 2023 Sep 18; Vol. 15 (9). Date of Electronic Publication: 2023 Sep 18.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*
Simian Acquired Immunodeficiency Syndrome*/drug therapy
Simian Immunodeficiency Virus*
Animals ; Humans ; CD8-Positive T-Lymphocytes ; Macaca mulatta ; Interleukin-17/therapeutic use ; Intestinal Mucosa
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques.
Autorzy:
Podgorski RM; Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Robinson JA; Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Smith MD; Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Mallick S; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhao H; Center for Biostatistics and Epidemiology, Department of Biomedical Education and Data Science, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Veazey RS; Tulane National Primate Research Center, Tulane School of Medicine, Covington, LA, USA.
Kolson DL; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Bar KJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. .
Burdo TH; Center for NeuroVirology and Gene Editing, Department of Microbiology, Immunology, and Inflammation, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. .
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Źródło:
Retrovirology [Retrovirology] 2023 Aug 10; Vol. 20 (1), pp. 13. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Simian Acquired Immunodeficiency Syndrome*/drug therapy
HIV Infections*/drug therapy
Simian Immunodeficiency Virus*/genetics
HIV-1*/genetics
Animals ; Humans ; Macaca mulatta ; Antiretroviral Therapy, Highly Active ; Brain ; Virus Replication/physiology ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Downregulation of CCR5 on brain perivascular macrophages in simian immunodeficiency virus-infected rhesus macaques.
Autorzy:
Hattler JB; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia, USA.
Irons DL; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia, USA.
Luo J; Department of Health Systems and Population Health Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, Texas, USA.
Kim WK; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia, USA.; Division of Microbiology, Tulane National Primate Research Center, Covington, Louisiana, USA.; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
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Źródło:
Brain and behavior [Brain Behav] 2023 Aug; Vol. 13 (8), pp. e3126. Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Encephalitis*/metabolism
Receptors, CCR5*/genetics
Receptors, CCR5*/metabolism
Simian Acquired Immunodeficiency Syndrome*/metabolism
Simian Acquired Immunodeficiency Syndrome*/pathology
Simian Immunodeficiency Virus*/metabolism
Animals ; Brain/pathology ; Clathrin/metabolism ; Down-Regulation ; Macaca mulatta/metabolism ; Macrophages ; Receptors, Chemokine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load.
Autorzy:
Cody JW; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States of America.
Ellis-Connell AL; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
O'Connor SL; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Pienaar E; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States of America.; Regenstrief Center for Healthcare Engineering, Purdue University, West Lafayette, Indiana, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Aug 24; Vol. 19 (8), pp. e1011425. Date of Electronic Publication: 2023 Aug 24 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Simian Immunodeficiency Virus*
Animals ; Interleukin-15 ; Viral Load ; Immunotherapy ; CD8-Positive T-Lymphocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor.
Autorzy:
Twentyman J; Department of Global Health, University of Washington, Seattle, WA, USA.; Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Khalifeh A; Department of Molecular and Cell Biology, Division of Immunology and Molecular Medicine, University of California -Berkeley, Berkeley, CA, USA.
Felton AL; Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Emerman M; Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Ohainle M; Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .; Department of Molecular and Cell Biology, Division of Immunology and Molecular Medicine, University of California -Berkeley, Berkeley, CA, USA. .
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Źródło:
Retrovirology [Retrovirology] 2023 Aug 22; Vol. 20 (1), pp. 15. Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Simian Immunodeficiency Virus*/genetics
HIV Infections*
Animals ; Macaca mulatta ; Lentivirus ; Antiviral Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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