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Wyszukujesz frazę ""small ubiquitin-related modifier"" wg kryterium: Temat


Tytuł :
Enhanced Live-Cell Delivery of Synthetic Proteins Assisted by Cell-Penetrating Peptides Fused to DABCYL.
Autorzy :
Mandal S; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, 3200008, Haifa, Israel.
Mann G; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, 3200008, Haifa, Israel.
Satish G; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, 3200008, Haifa, Israel.
Brik A; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, 3200008, Haifa, Israel.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Mar 22; Vol. 60 (13), pp. 7333-7343. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell-Penetrating Peptides/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Ubiquitin/*metabolism
p-Dimethylaminoazobenzene/*analogs & derivatives
Cell Line, Tumor ; Cell-Penetrating Peptides/chemistry ; Fluorescence ; Humans ; Molecular Structure ; Small Ubiquitin-Related Modifier Proteins/chemical synthesis ; Small Ubiquitin-Related Modifier Proteins/chemistry ; Ubiquitin/chemical synthesis ; Ubiquitin/chemistry ; p-Dimethylaminoazobenzene/chemistry ; p-Dimethylaminoazobenzene/metabolism
Czasopismo naukowe
Tytuł :
Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ.
Autorzy :
Dodat F; Faculté de Pharmacie, Université de Montréal, Montréal, QC, Canada.
Cotnoir-White D; Faculté de Pharmacie, Université de Montréal, Montréal, QC, Canada; Institut de Recherche en Immunologie et Cancérologie (IRIC), Université de Montréal et Département de biochimie et médecine moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.
Dianati E; Institut de Recherche en Immunologie et Cancérologie (IRIC), Université de Montréal et Département de biochimie et médecine moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.
Vallet A; Institut de Recherche en Immunologie et Cancérologie (IRIC), Université de Montréal et Département de biochimie et médecine moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.
Mader S; Institut de Recherche en Immunologie et Cancérologie (IRIC), Université de Montréal et Département de biochimie et médecine moléculaire, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.
Lévesque D; Faculté de Pharmacie, Université de Montréal, Montréal, QC, Canada. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2021 Feb; Vol. 1868 (2), pp. 118908. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcriptional Activation*
Nuclear Receptor Subfamily 4, Group A, Member 1/*metabolism
Poly-ADP-Ribose Binding Proteins/*metabolism
Protein Inhibitors of Activated STAT/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Transcription, Genetic/*genetics
Cysteine Endopeptidases/genetics ; Cysteine Endopeptidases/metabolism ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Plasmids/genetics ; Poly-ADP-Ribose Binding Proteins/genetics ; Protein Inhibitors of Activated STAT/genetics ; Signal Transduction/genetics ; Small Ubiquitin-Related Modifier Proteins/genetics ; Transfection
Czasopismo naukowe
Tytuł :
The SUMO pathway in pancreatic cancer: insights and inhibition.
Autorzy :
Schneeweis C; Medical Clinic and Polyclinic II, Klinikum rechts der Isar, Technical University Munich, 81675, München, Germany.
Hassan Z; Medical Clinic and Polyclinic II, Klinikum rechts der Isar, Technical University Munich, 81675, München, Germany.
Schick M; Department of Hematology, Oncology and Tumor Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Germany.
Keller U; Department of Hematology, Oncology and Tumor Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Germany. .; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120, Heidelberg, Germany. .; Max-Delbrück-Center for Molecular Medicine, 13092, Berlin, Germany. .
Schneider G; Medical Clinic and Polyclinic II, Klinikum rechts der Isar, Technical University Munich, 81675, München, Germany. .; German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120, Heidelberg, Germany. .
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Źródło :
British journal of cancer [Br J Cancer] 2021 Feb; Vol. 124 (3), pp. 531-538. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Protein Processing, Post-Translational*
Carcinoma, Pancreatic Ductal/*metabolism
Pancreatic Neoplasms/*metabolism
Proto-Oncogene Proteins c-myc/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Carcinoma, Pancreatic Ductal/pathology ; Cell Survival/physiology ; Cysteine Endopeptidases/drug effects ; Cysteine Endopeptidases/metabolism ; DNA Repair/physiology ; Enzyme Inhibitors/pharmacology ; Humans ; Mitosis/physiology ; Pancreatic Neoplasms/pathology ; Poly-ADP-Ribose Binding Proteins/metabolism ; Promyelocytic Leukemia Protein/metabolism ; Protein Inhibitors of Activated STAT/metabolism ; Proto-Oncogene Proteins c-myc/genetics ; SUMO-1 Protein/antagonists & inhibitors ; SUMO-1 Protein/metabolism ; Signal Transduction/physiology ; Small Ubiquitin-Related Modifier Proteins/antagonists & inhibitors ; Sumoylation/drug effects ; Synthetic Lethal Mutations ; Ubiquitin-Conjugating Enzymes/antagonists & inhibitors ; Ubiquitin-Conjugating Enzymes/metabolism ; Ubiquitins/antagonists & inhibitors ; Ubiquitins/metabolism
Czasopismo naukowe
Tytuł :
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Autorzy :
Morozko EL; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Smith-Geater C; Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697.
Monteys AM; Raymond G. Perelman Center for Cell and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Pradhan S; Department of Neurology, University of Texas Medical Branch, Galveston, TX 77555.
Lim RG; Institute of Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.
Langfelder P; Department of Human Genetics, David Geffen School of Medicine at University of California, Los Angeles, CA 90095.
Kachemov M; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Hill A; Incisive Genetics Inc., Vancouver, BC, Canada V6A 0H9.
Stocksdale JT; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Cullis PR; NanoMedicines Innovation Network, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.
Wu J; Department of Biological Chemistry, University of California, Irvine, CA 92697.
Ochaba J; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Miramontes R; Institute of Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.
Chakraborty A; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555.
Hazra TK; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555.
Lau A; Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697.
St-Cyr S; Raymond G. Perelman Center for Cell and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Orellana I; Sue and Bill Gross Stem Cell Institute, University of California, Irvine, CA 92697.
Kopan L; Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697.
Wang KQ; Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697.
Yeung S; Institute of Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.
Leavitt BR; Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada V5Z 4H4.
Reidling JC; Institute of Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.
Yang XW; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095.
Steffan JS; Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697.; Institute of Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.
Davidson BL; Raymond G. Perelman Center for Cell and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Sarkar PS; Department of Neurology, University of Texas Medical Branch, Galveston, TX 77555.; Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555.
Thompson LM; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697; .; Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697.; Institute of Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697.; Department of Biological Chemistry, University of California, Irvine, CA 92697.; Sue and Bill Gross Stem Cell Institute, University of California, Irvine, CA 92697.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 26; Vol. 118 (4).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA Repair*
Protein Processing, Post-Translational*
DNA/*genetics
DNA Repair Enzymes/*genetics
Huntingtin Protein/*genetics
Huntington Disease/*genetics
Phosphotransferases (Alcohol Group Acceptor)/*genetics
Protein Inhibitors of Activated STAT/*genetics
Small Ubiquitin-Related Modifier Proteins/*genetics
Animals ; Cell Differentiation ; DNA/metabolism ; DNA Damage ; DNA Repair Enzymes/metabolism ; Disease Models, Animal ; Female ; Humans ; Huntingtin Protein/metabolism ; Huntington Disease/metabolism ; Huntington Disease/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/metabolism ; Neurons/pathology ; Phosphotransferases (Alcohol Group Acceptor)/metabolism ; Pluripotent Stem Cells/metabolism ; Pluripotent Stem Cells/pathology ; Primary Cell Culture ; Protein Inhibitors of Activated STAT/antagonists & inhibitors ; Protein Inhibitors of Activated STAT/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Small Ubiquitin-Related Modifier Proteins/antagonists & inhibitors ; Small Ubiquitin-Related Modifier Proteins/metabolism ; Sumoylation ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Current Status of SUMOylation Inhibitors.
Autorzy :
Brackett CM; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Blagg BSJ; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
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Źródło :
Current medicinal chemistry [Curr Med Chem] 2021; Vol. 28 (20), pp. 3892-3912.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Small Ubiquitin-Related Modifier Proteins*/genetics
Small Ubiquitin-Related Modifier Proteins*/metabolism
Sumoylation*
Humans ; Ligases ; Lysine ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Autorzy :
Marmor-Kollet H; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Siany A; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Kedersha N; Division of Rheumatology, Immunity, and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA.
Knafo N; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Rivkin N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Danino YM; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Moens TG; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
Olender T; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Sheban D; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Cohen N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Dadosh T; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot 7610001, Israel.
Addadi Y; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot 7610001, Israel.
Ravid R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Eitan C; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Toth Cohen B; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Hofmann S; Division of Rheumatology, Immunity, and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA.
Riggs CL; Division of Rheumatology, Immunity, and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA.
Advani VM; Division of Rheumatology, Immunity, and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA.
Higginbottom A; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield S10 2HQ, UK.
Cooper-Knock J; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield S10 2HQ, UK.
Hanna JH; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Merbl Y; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Van Den Bosch L; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
Anderson P; Division of Rheumatology, Immunity, and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA.
Ivanov P; Division of Rheumatology, Immunity, and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA.
Geiger T; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA 02115, USA; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel. Electronic address: .
Hornstein E; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Dec 03; Vol. 80 (5), pp. 876-891.e6. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Sumoylation*
Amyotrophic Lateral Sclerosis/*metabolism
C9orf72 Protein/*metabolism
Cytoplasmic Granules/*metabolism
Drosophila Proteins/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; C9orf72 Protein/genetics ; Cell Line, Tumor ; Cytoplasmic Granules/genetics ; Cytoplasmic Granules/pathology ; Dipeptides/genetics ; Dipeptides/metabolism ; Drosophila Proteins/genetics ; Drosophila melanogaster ; Humans ; Mice ; Proteomics ; Small Ubiquitin-Related Modifier Proteins/genetics
Czasopismo naukowe
Tytuł :
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal.
Autorzy :
Kramarz K; Institut Curie, PSL Research University, UMR3348, F-91405, Orsay, France.; CNRS UMR3348 'Genome integrity, RNA and Cancer', 'Equipe labellisée LIGUE 2020', F-91405, Orsay, France.; University Paris Sud, Paris-Saclay University, UMR3348, F-91405, Orsay, France.
Schirmeisen K; Institut Curie, PSL Research University, UMR3348, F-91405, Orsay, France.; CNRS UMR3348 'Genome integrity, RNA and Cancer', 'Equipe labellisée LIGUE 2020', F-91405, Orsay, France.; University Paris Sud, Paris-Saclay University, UMR3348, F-91405, Orsay, France.
Boucherit V; Institut Curie, PSL Research University, UMR3348, F-91405, Orsay, France.; CNRS UMR3348 'Genome integrity, RNA and Cancer', 'Equipe labellisée LIGUE 2020', F-91405, Orsay, France.; University Paris Sud, Paris-Saclay University, UMR3348, F-91405, Orsay, France.
Ait Saada A; Institut Curie, PSL Research University, UMR3348, F-91405, Orsay, France.; CNRS UMR3348 'Genome integrity, RNA and Cancer', 'Equipe labellisée LIGUE 2020', F-91405, Orsay, France.; University Paris Sud, Paris-Saclay University, UMR3348, F-91405, Orsay, France.
Lovo C; Institut Curie, PSL Research University, UMR3348, F-91405, Orsay, France.; CNRS UMR3348 'Genome integrity, RNA and Cancer', 'Equipe labellisée LIGUE 2020', F-91405, Orsay, France.
Palancade B; Université de Paris, CNRS, Institut Jacques Monod, F-75006, Paris, France.
Freudenreich C; Department of Biology, Tufts University, Medford, MA, 02155, USA.
Lambert SAE; Institut Curie, PSL Research University, UMR3348, F-91405, Orsay, France. .; CNRS UMR3348 'Genome integrity, RNA and Cancer', 'Equipe labellisée LIGUE 2020', F-91405, Orsay, France. .; University Paris Sud, Paris-Saclay University, UMR3348, F-91405, Orsay, France. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 06; Vol. 11 (1), pp. 5643. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Nuclear Pore/*metabolism
Proteasome Endopeptidase Complex/*genetics
Schizosaccharomyces/*genetics
Schizosaccharomyces/*metabolism
Schizosaccharomyces pombe Proteins/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
DNA Replication ; Ligases/genetics ; Ligases/metabolism ; Nuclear Pore/genetics ; Proteasome Endopeptidase Complex/metabolism ; Recombination, Genetic ; Schizosaccharomyces/growth & development ; Schizosaccharomyces pombe Proteins/genetics ; Small Ubiquitin-Related Modifier Proteins/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Effect of endosulfan and bisphenol A on the expression of SUMO and UBC9.
Autorzy :
Yarahalli Jayaram V; Department of Biotechnology, BMS College of Engineering, Bengaluru, India.
Baggavalli S; Connexios Life Sciences Pvt Ltd, Bengaluru, India.
Reddy D; Department of Biotechnology, BMS College of Engineering, Bengaluru, India.
Sistla S; GE Health-care Lifesciences, Bengaluru, India.
Malempati R; Department of Biotechnology, BMS College of Engineering, Bengaluru, India.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2020 Nov; Vol. 43 (6), pp. 637-644. Date of Electronic Publication: 2018 Nov 14.
Typ publikacji :
Journal Article
MeSH Terms :
Adipocytes/*drug effects
Benzhydryl Compounds/*toxicity
Endosulfan/*toxicity
Hepatocytes/*drug effects
Myoblasts, Skeletal/*drug effects
Phenols/*toxicity
SUMO-1 Protein/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Ubiquitin-Conjugating Enzymes/*metabolism
Ubiquitins/*metabolism
3T3-L1 Cells ; Adipocytes/enzymology ; Adipocytes/pathology ; Animals ; Benzhydryl Compounds/metabolism ; Endosulfan/metabolism ; Hep G2 Cells ; Hepatocytes/enzymology ; Hepatocytes/pathology ; Humans ; Mice ; Molecular Docking Simulation ; Myoblasts, Skeletal/enzymology ; Myoblasts, Skeletal/pathology ; Oxidative Stress/drug effects ; Phenols/metabolism ; Protein Binding ; Reactive Oxygen Species/metabolism ; SUMO-1 Protein/genetics ; Small Ubiquitin-Related Modifier Proteins/genetics ; Sumoylation ; Ubiquitin-Conjugating Enzymes/genetics ; Ubiquitins/genetics
Czasopismo naukowe
Tytuł :
Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice.
Autorzy :
Yu S; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China.
Galeffi F; Research and Surgery Services, Durham VAMC, Durham, NC, USA.; Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.; Department of Biomedical Engineering, Duke University Medical Center, Durham, NC, USA.
Rodriguiz RM; Department of Psychiatry and Behavioral Sciences, Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, USA.
Wang Z; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Shen Y; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China.
Lyu J; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Li R; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Bernstock JD; Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, MD, USA.
Johnson KR; Bioinformatics Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health (NINDS/NIH), Bethesda, MD, USA.
Liu S; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Sheng H; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Turner DA; Research and Surgery Services, Durham VAMC, Durham, NC, USA.; Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.; Department of Biomedical Engineering, Duke University Medical Center, Durham, NC, USA.
Wetsel WC; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Mouse Behavioral and Neuroendocrine Analysis Core Facility, Duke University Medical Center, Durham, NC, USA.; Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.
Paschen W; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Yang W; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 14750-14767. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Memory*
Small Ubiquitin-Related Modifier Proteins/*metabolism
Animals ; Cognition ; Female ; Hippocampus/metabolism ; Hippocampus/physiology ; Long-Term Potentiation ; Male ; Mice ; Mice, Inbred C57BL ; Prosencephalon/metabolism ; Prosencephalon/physiology ; Small Ubiquitin-Related Modifier Proteins/genetics
Czasopismo naukowe
Tytuł :
Simplified detection of polyhistidine-tagged proteins in gels and membranes using a UV-excitable dye and a multiple chelator head pair.
Autorzy :
Raducanu VS; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Isaioglou I; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Raducanu DV; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Merzaban JS; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Hamdan SM; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Aug 21; Vol. 295 (34), pp. 12214-12223. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Denaturing Gradient Gel Electrophoresis*
Ultraviolet Rays*
Fluorescent Dyes/*chemistry
Histidine/*analysis
Recombinant Fusion Proteins/*analysis
Small Ubiquitin-Related Modifier Proteins/*analysis
Histidine/chemistry ; Humans ; Recombinant Fusion Proteins/chemistry ; Small Ubiquitin-Related Modifier Proteins/chemistry ; Small Ubiquitin-Related Modifier Proteins/genetics
Czasopismo naukowe
Tytuł :
The Leishmania donovani SENP Protease Is Required for SUMO Processing but Not for Viability.
Autorzy :
Bea A; Leishmaniasis Group, Bernhard Nocht Institute for Tropical Medicine, D-20359 Hamburg, Germany.
Kröber-Boncardo C; Leishmaniasis Group, Bernhard Nocht Institute for Tropical Medicine, D-20359 Hamburg, Germany.
Sandhu M; Leishmaniasis Group, Bernhard Nocht Institute for Tropical Medicine, D-20359 Hamburg, Germany.; Boehringer Ingelheim RCV, A-1121 Vienna, Austria.
Brinker C; Leishmaniasis Group, Bernhard Nocht Institute for Tropical Medicine, D-20359 Hamburg, Germany.
Clos J; Leishmaniasis Group, Bernhard Nocht Institute for Tropical Medicine, D-20359 Hamburg, Germany.
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Źródło :
Genes [Genes (Basel)] 2020 Oct 14; Vol. 11 (10). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Processing, Post-Translational*
Sumoylation*
Cysteine Endopeptidases/*metabolism
Leishmania donovani/*metabolism
Leishmaniasis/*parasitology
Macrophages/*cytology
Small Ubiquitin-Related Modifier Proteins/*metabolism
Animals ; Cells, Cultured ; Cysteine Endopeptidases/genetics ; Leishmania donovani/genetics ; Leishmaniasis/genetics ; Leishmaniasis/metabolism ; Macrophages/metabolism ; Macrophages/parasitology ; Mice ; Small Ubiquitin-Related Modifier Proteins/genetics ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Revealing USP7 Deubiquitinase Substrate Specificity by Unbiased Synthesis of Ubiquitin Tagged SUMO2.
Autorzy :
Jiang HK; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei 11529, Taiwan.; Department of Chemistry, National Tsing Hua University, Hsinchu 30044, Taiwan.
Kurkute P; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei 11529, Taiwan.; Department of Chemistry, National Taiwan University, Taipei 10617, Taiwan.
Li CL; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan.
Wang YH; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.
Chen PJ; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan.
Lin SY; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.
Wang YS; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei 11529, Taiwan.; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan.
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Źródło :
Biochemistry [Biochemistry] 2020 Oct 13; Vol. 59 (40), pp. 3796-3801. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Small Ubiquitin-Related Modifier Proteins/*metabolism
Ubiquitin/*metabolism
Ubiquitin-Specific Peptidase 7/*metabolism
Humans ; Models, Molecular ; Protein Domains ; Protein Multimerization ; Small Ubiquitin-Related Modifier Proteins/chemistry ; Substrate Specificity ; Sumoylation ; Ubiquitin/chemistry ; Ubiquitin-Specific Peptidase 7/chemistry ; Ubiquitination
Czasopismo naukowe
Tytuł :
SUMO: From Bench to Bedside.
Autorzy :
Chang HM; Center for Precision Medicine, Department of Medicine, University of Missouri, Columbia, Missouri.
Yeh ETH; Center for Precision Medicine, Department of Medicine, University of Missouri, Columbia, Missouri.
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Źródło :
Physiological reviews [Physiol Rev] 2020 Oct 01; Vol. 100 (4), pp. 1599-1619.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Small Ubiquitin-Related Modifier Proteins/*metabolism
Adaptive Immunity/physiology ; Animals ; Cardiovascular Diseases/metabolism ; Diabetes Mellitus/metabolism ; Humans ; Neoplasms/metabolism ; Protein Processing, Post-Translational ; Small Ubiquitin-Related Modifier Proteins/genetics
Czasopismo naukowe
Tytuł :
TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.
Autorzy :
Li M; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000.
Xu X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000.
Chang CW; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000.
Liu Y; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 22; Vol. 117 (38), pp. 23588-23596. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Replication/*genetics
Proliferating Cell Nuclear Antigen/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
Ubiquitin-Protein Ligases/*metabolism
DNA Breaks ; HEK293 Cells ; Humans ; Proliferating Cell Nuclear Antigen/genetics ; RecQ Helicases/genetics ; RecQ Helicases/metabolism ; Small Ubiquitin-Related Modifier Proteins/genetics ; Tripartite Motif-Containing Protein 28/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
A Fluorescence-Based Assay to Monitor SUMOylation in Real-Time.
Autorzy :
Tripathi V; National Center for Biological Sciences, TIFR, Bangalore, India.
Das R; National Center for Biological Sciences, TIFR, Bangalore, India.
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Źródło :
Current protocols in protein science [Curr Protoc Protein Sci] 2020 Sep; Vol. 101 (1), pp. e111.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Processing, Post-Translational*
SUMO-1 Protein/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Spectrometry, Fluorescence/*methods
Ubiquitin-Conjugating Enzymes/*metabolism
Fluorescein-5-isothiocyanate/chemistry ; Fluoresceins/chemistry ; Fluorescence Polarization ; Fluorescent Dyes/chemistry ; Humans ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; SUMO-1 Protein/genetics ; Small Ubiquitin-Related Modifier Proteins/genetics ; Sulfonic Acids/chemistry ; Sumoylation ; Ubiquitin-Conjugating Enzymes/genetics
Czasopismo naukowe
Tytuł :
Reply to Comment on "N-terminal Protein Tail Acts as Aggregation Protective Entropic Bristles: The SUMO Case".
Autorzy :
Graña-Montes R; Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, Zürich 8057, Switzerland.
Ventura S; Institut de Biotecnologia i de Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Bellaterra, Barcelona 08193, Spain.
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Źródło :
Biomacromolecules [Biomacromolecules] 2020 Aug 10; Vol. 21 (8), pp. 3483-3484. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Letter; Comment
MeSH Terms :
Small Ubiquitin-Related Modifier Proteins*/genetics
Entropy
Opinia redakcyjna
Tytuł :
Not So Slim Anymore-Evidence for the Role of SUMO in the Regulation of Lipid Metabolism.
Autorzy :
Sapir A; Department of Biology and the Environment, Faculty of Natural Sciences, University of Haifa-Oranim, Tivon 36006, Israel.
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Źródło :
Biomolecules [Biomolecules] 2020 Aug 06; Vol. 10 (8). Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Lipid Metabolism*
Lipid Metabolism Disorders/*genetics
Small Ubiquitin-Related Modifier Proteins/*metabolism
Animals ; Humans ; Lipid Metabolism Disorders/metabolism ; Small Ubiquitin-Related Modifier Proteins/genetics
Czasopismo naukowe
Tytuł :
SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability.
Autorzy :
Chang YC; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minnesota, MN 55455, USA.
Oram MK; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minnesota, MN 55455, USA.
Bielinsky AK; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minnesota, MN 55455, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 20; Vol. 22 (10). Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genomic Instability/*genetics
Small Ubiquitin-Related Modifier Proteins/*genetics
Sumoylation/*genetics
Ubiquitin/*genetics
Ubiquitin-Protein Ligases/*genetics
Animals ; DNA Repair/genetics ; Humans
Czasopismo naukowe

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