Temat: "stellate cells" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Corylin Attenuates CCl 4 -Induced Liver Fibrosis in Mice by Regulating the GAS6/AXL Signaling Pathway in Hepatic Stellate Cells.
Autorzy:: Chen CC; Biobank, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.; Graduate Institute of Natural Products, Chang Gung University, Tao-Yuan 33303, Taiwan.
Chen CY; Biobank, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.; Graduate Institute of Health Industry and Technology, Research Center for Chinese Herbal Medicine and Research Center for Food and Cosmetic Safety, Chang Gung University of Science and Technology, Tao-Yuan 33303, Taiwan.
Yeh CT; Liver Research Center, Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.
Liu YT; Biobank, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.
Leu YL; Biobank, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.; Graduate Institute of Natural Products, Chang Gung University, Tao-Yuan 33303, Taiwan.
Chuang WY; Department of Anatomic Pathology, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.; College of Medicine, Chang Gung University, Tao-Yuan 33303, Taiwan.
Shih YH; Department of Healthcare Administration, Asia University, Taichung 41354, Taiwan.
Chou LF; Kidney Research Center, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.
Shieh TM; School of Dentistry, China Medical University, Taichung 40402, Taiwan.
Wang TH; Biobank, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.; Graduate Institute of Natural Products, Chang Gung University, Tao-Yuan 33303, Taiwan.; Graduate Institute of Health Industry and Technology, Research Center for Chinese Herbal Medicine and Research Center for Food and Cosmetic Safety, Chang Gung University of Science and Technology, Tao-Yuan 33303, Taiwan.; Liver Research Center, Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Tao-Yuan 33305, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 29; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Animals ; Humans ; Mice ; Anti-Inflammatory Agents/adverse effects ; Carbon Tetrachloride ; Flavonoids/pharmacology ; Flavonoids/therapeutic use ; Liver/metabolism ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Signal Transduction

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Skocz do pozycji: 2.

Tytuł:: Sex Drives Functional Changes in the Progression and Regression of Liver Fibrosis.
Autorzy:: Sayaf K; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35131 Padova, Italy.
Zanotto I; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35128 Padova, Italy.
Gabbia D; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35128 Padova, Italy.
Alberti D; Laboratory of Synthetic Immunology, Department of Surgery Oncology and Gastroenterology, University of Padova, 35128 Padova, Italy.; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
Pasqual G; Laboratory of Synthetic Immunology, Department of Surgery Oncology and Gastroenterology, University of Padova, 35128 Padova, Italy.; Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
Zaramella A; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35131 Padova, Italy.; Gastroenterology Unit, Veneto Institute of Oncology IOV-IRCCS, University of Padova, 35128 Padova, Italy.
Fantin A; Gastroenterology Unit, Veneto Institute of Oncology IOV-IRCCS, University of Padova, 35128 Padova, Italy.
De Martin S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35128 Padova, Italy.
Russo FP; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35131 Padova, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 17; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*/pathology
Liver Cirrhosis*/pathology
Male ; Mice ; Female ; Animals ; Liver/pathology ; Phenotype ; Carbon Tetrachloride/toxicity

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Skocz do pozycji: 3.

Tytuł:: The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
Autorzy:: Yan M; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China.; The School of Medical, Lanzhou University, Lanzhou 730000, China.
Xie Y; The School of Medical, Lanzhou University, Lanzhou 730000, China.; Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province, Lanzhou 730000, China.
Yao J; The School of Medical, Lanzhou University, Lanzhou 730000, China.; Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province, Lanzhou 730000, China.
Li X; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China.; The School of Medical, Lanzhou University, Lanzhou 730000, China.; Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province, Lanzhou 730000, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 23; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 23.
Typ publikacji:: Journal Article
MeSH Terms:: Myofibroblasts*/metabolism
Hepatic Stellate Cells*/metabolism
Humans ; Liver Cirrhosis/metabolism ; Collagen/metabolism ; Transforming Growth Factor beta/metabolism ; Actins/metabolism ; Transforming Growth Factor beta1/metabolism ; Liver/metabolism

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Skocz do pozycji: 4.

Tytuł:: Parkin-Mediated Mitophagy by TGF-β Is Connected with Hepatic Stellate Cell Activation.
Autorzy:: Lee JH; College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
Kim KM; College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.; Department of Biomedical Science, College of Natural Science, Chosun University, Gwangju 61452, Republic of Korea.
Jung EH; College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
Lee HR; College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
Yang JH; College of Korean Medicine, Dongshin University, Naju 58245, Republic of Korea.
Cho SS; College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.
Ki SH; College of Pharmacy, Chosun University, Gwangju 61452, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 02; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 02.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*
Transforming Growth Factor beta*/pharmacology
Animals ; Humans ; Mice ; Liver/pathology ; Liver Cirrhosis/pathology ; Mitophagy ; Signal Transduction ; Transforming Growth Factor beta1/genetics ; Ubiquitin-Protein Ligases/genetics

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Skocz do pozycji: 5.

Tytuł:: KLF10 Inhibits TGF-β-Mediated Activation of Hepatic Stellate Cells via Suppression of ATF3 Expression.
Autorzy:: Hwang S; Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.
Park S; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.
Yaseen U; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.
Lee HJ; Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.
Cha JY; Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 09; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*
Liver Cirrhosis*/genetics
Humans ; Animals ; Mice ; Transforming Growth Factor beta ; Mice, Knockout ; Kruppel-Like Transcription Factors/genetics ; Early Growth Response Transcription Factors/genetics ; Activating Transcription Factor 3/genetics

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Skocz do pozycji: 6.

Tytuł:: Analysis of the Role of Stellate Cell VCAM-1 in NASH Models in Mice.
Autorzy:: Chung KJ; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Legaki AI; Department of Physiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.
Papadopoulos G; Department of Physiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.
Gercken B; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Gebler J; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Schwabe RF; Department of Medicine, Columbia University, New York, NY 10032, USA.
Chavakis T; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Chatzigeorgiou A; Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.; Department of Physiology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527 Athens, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 02; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*/metabolism
Hepatic Stellate Cells*/pathology
Non-alcoholic Fatty Liver Disease*/metabolism
Non-alcoholic Fatty Liver Disease*/pathology
Vascular Cell Adhesion Molecule-1*/metabolism
Animals ; Mice ; Inflammation/metabolism ; Liver/metabolism ; Liver Cirrhosis/metabolism ; Mice, Inbred C57BL ; Disease Models, Animal

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Skocz do pozycji: 7.

Tytuł:: 5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In Vitro.
Autorzy:: Almanzar VMD; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Shah K; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
LaComb JF; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Mojumdar A; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Patel HR; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Cheung J; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Tang M; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Ju J; Department of Pathology, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Bialkowska AB; Department of Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Fluorouracil*/pharmacology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Pancreatic Stellate Cells*/drug effects
Pancreatic Stellate Cells*/pathology
Pancreatitis, Chronic*/pathology
Animals ; Mice ; Cell Proliferation/genetics ; Fibrosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; YAP-Signaling Proteins/metabolism

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Skocz do pozycji: 8.

Tytuł:: The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Autorzy:: Wang Y; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Li X; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Guan X; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Song Z; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Liu H; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Guan Z; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Wang J; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhu L; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhang D; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhao L; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Xie P; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Wei X; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Shang N; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Liu Y; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Jin Z; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Ji Z; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Dai G; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/metabolism
Rats ; Humans ; Mice ; Animals ; Hepatic Stellate Cells/metabolism ; Leucine/metabolism ; Up-Regulation ; Liver Cirrhosis/metabolism ; Liver/metabolism ; Transforming Growth Factor beta1/metabolism ; Smad Proteins/metabolism

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Skocz do pozycji: 9.

Tytuł:: Eupatilin Ameliorates Hepatic Fibrosis and Hepatic Stellate Cell Activation by Suppressing β-catenin/PAI-1 Pathway.
Autorzy:: Hu J; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.
Liu Y; Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China.
Pan Z; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.
Huang X; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.; Department of Traditional Chinese Medicine, Chongqing College of Traditional Chinese Medicine, Chongqing 402760, China.
Wang J; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.; Department of Traditional Chinese Medicine, Chongqing College of Traditional Chinese Medicine, Chongqing 402760, China.
Cao W; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.
Chen Z; Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases, College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing 400016, China.; Department of Traditional Chinese Medicine, Chongqing College of Traditional Chinese Medicine, Chongqing 402760, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 21; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 21.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*/metabolism
Plasminogen Activator Inhibitor 1*/genetics
Plasminogen Activator Inhibitor 1*/metabolism
Humans ; Mice ; Animals ; Liver Cirrhosis/metabolism ; Flavonoids/adverse effects ; Fibrosis

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Skocz do pozycji: 10.

Tytuł:: Ivermectin Attenuates CCl 4 -Induced Liver Fibrosis in Mice by Suppressing Hepatic Stellate Cell Activation.
Autorzy:: Ying H; Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China.
Li L; Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China.; Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences, Ningbo University, Ningbo 315211, China.
Zhao Y; Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China.; Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences, Ningbo University, Ningbo 315211, China.
Ni F; Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China.; Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences, Ningbo University, Ningbo 315211, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 16; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:: Journal Article
MeSH Terms:: Ivermectin*/pharmacology
Ivermectin*/therapeutic use
Hepatic Stellate Cells*/metabolism
Mice ; Rats ; Animals ; Signal Transduction ; Transforming Growth Factor beta1/metabolism ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Liver/metabolism ; Carbon Tetrachloride/toxicity

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Skocz do pozycji: 11.

Tytuł:: Therapeutic Strategies for Pancreatic-Cancer-Related Type 2 Diabetes Centered around Natural Products.
Autorzy:: Park MN; Department of Pathology, College of Korean Medicine, Kyung Hee University, Hoegidong Dongdaemungu, Seoul 05253, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 02; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Diabetes Mellitus, Type 2*/metabolism
Biological Products*/pharmacology
Biological Products*/therapeutic use
Biological Products*/metabolism
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/etiology
Pancreatic Neoplasms*/metabolism
Carcinoma, Pancreatic Ductal*/drug therapy
Carcinoma, Pancreatic Ductal*/etiology
Carcinoma, Pancreatic Ductal*/metabolism
Humans ; Pancreatic Stellate Cells/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 12.

Tytuł:: GRP94 Inhabits the Immortalized Porcine Hepatic Stellate Cells Apoptosis under Endoplasmic Reticulum Stress through Modulating the Expression of IGF-1 and Ubiquitin.
Autorzy:: Wang X; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Xin H; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Zhang C; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Gu X; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Hao Y; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 14; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:: Journal Article
MeSH Terms:: Endoplasmic Reticulum Stress*
Hepatic Stellate Cells*/metabolism
Humans ; Animals ; Rats ; Mice ; Swine ; Insulin-Like Growth Factor Binding Protein 3/metabolism ; Insulin-Like Growth Factor I/metabolism ; Ubiquitin/metabolism ; Apoptosis

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Skocz do pozycji: 13.

Tytuł:: Enhanced Expression of ARK5 in Hepatic Stellate Cell and Hepatocyte Synergistically Promote Liver Fibrosis.
Autorzy:: You Y; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.
Gao C; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.
Wu J; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.
Qu H; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.
Xiao Y; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.; Department of Hepatological Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510630, China.
Kang Z; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.
Li J; Department of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou 510630, China.
Hong J; Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510630, China.; Department of Hepatological Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510630, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 28; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells*/metabolism
Carbon Tetrachloride*/toxicity
Mice ; Animals ; Hepatocytes/metabolism ; Liver Cirrhosis/metabolism ; Receptor, Transforming Growth Factor-beta Type I/genetics ; Receptor, Transforming Growth Factor-beta Type I/metabolism ; Transforming Growth Factor beta/metabolism ; Liver/metabolism

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Skocz do pozycji: 14.

Tytuł:: MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury.
Autorzy:: Ariyachet C; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.; Center of Excellence in Hepatitis and Liver Cancer, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Chuaypen N; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.; Center of Excellence in Hepatitis and Liver Cancer, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Kaewsapsak P; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Chantaravisoot N; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Jindatip D; Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Potikanond S; Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; Research Center of Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.
Tangkijvanich P; Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.; Center of Excellence in Hepatitis and Liver Cancer, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 19; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Actin Cytoskeleton*/metabolism
Hepatic Stellate Cells*/metabolism
MicroRNAs*/metabolism
Cell Proliferation ; Humans ; Liver Cirrhosis/metabolism ; Organoids/metabolism ; Signal Transduction

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Skocz do pozycji: 15.

Tytuł:: Senescent Human Pancreatic Stellate Cells Secrete CXCR2 Agonist CXCLs to Promote Proliferation and Migration of Human Pancreatic Cancer AsPC-1 and MIAPaCa-2 Cell Lines.
Autorzy:: Takikawa T; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Hamada S; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Matsumoto R; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Tanaka Y; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Kataoka F; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Sasaki A; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Masamune A; Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 17; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Pancreatic Neoplasms*/metabolism
Pancreatic Stellate Cells*/metabolism
Cell Line, Tumor ; Cell Proliferation ; Cellular Senescence ; Culture Media, Conditioned/metabolism ; Culture Media, Conditioned/pharmacology ; Humans ; Receptors, Interleukin-8B/genetics ; Receptors, Interleukin-8B/metabolism ; Pancreatic Neoplasms

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Skocz do pozycji: 16.

Tytuł:: Cold Atmospheric Plasma Does Not Affect Stellate Cells Phenotype in Pancreatic Cancer Tissue in Ovo.
Autorzy:: Privat-Maldonado A; PLASMANT, Chemistry Department, Faculty of Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Solid Tumor Immunology Group, Center for Oncological Research, Integrated Personalized and Precision Oncology Network, Department of Molecular Imaging, Pathology, Radiotherapy and Oncology, University of Antwerp, 2610 Antwerp, Belgium.
Verloy R; PLASMANT, Chemistry Department, Faculty of Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Solid Tumor Immunology Group, Center for Oncological Research, Integrated Personalized and Precision Oncology Network, Department of Molecular Imaging, Pathology, Radiotherapy and Oncology, University of Antwerp, 2610 Antwerp, Belgium.
Cardenas Delahoz E; Industrial Vision Lab InViLab, Faculty of Applied Engineering, University of Antwerp, 2610 Antwerp, Belgium.
Lin A; PLASMANT, Chemistry Department, Faculty of Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Solid Tumor Immunology Group, Center for Oncological Research, Integrated Personalized and Precision Oncology Network, Department of Molecular Imaging, Pathology, Radiotherapy and Oncology, University of Antwerp, 2610 Antwerp, Belgium.
Vanlanduit S; Industrial Vision Lab InViLab, Faculty of Applied Engineering, University of Antwerp, 2610 Antwerp, Belgium.
Smits E; Solid Tumor Immunology Group, Center for Oncological Research, Integrated Personalized and Precision Oncology Network, Department of Molecular Imaging, Pathology, Radiotherapy and Oncology, University of Antwerp, 2610 Antwerp, Belgium.
Bogaerts A; PLASMANT, Chemistry Department, Faculty of Sciences, University of Antwerp, 2610 Antwerp, Belgium.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 10; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 10.
Typ publikacji:: Journal Article
MeSH Terms:: Pancreatic Neoplasms/*therapy
Pancreatic Stellate Cells/*drug effects
Plasma Gases/*pharmacology
Adenocarcinoma/metabolism ; Adenocarcinoma/therapy ; Animals ; Carcinoma, Pancreatic Ductal/metabolism ; Carcinoma, Pancreatic Ductal/therapy ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Chickens ; Extracellular Matrix/metabolism ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; Pancreatic Neoplasms/metabolism ; Pancreatic Stellate Cells/metabolism ; Phenotype ; Tumor Microenvironment/drug effects

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Skocz do pozycji: 17.

Tytuł:: Differential Effects of Pancreatic Cancer-Derived Extracellular Vesicles Driving a Suppressive Environment.
Autorzy:: Purushothaman A; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Oliva-Ramírez J; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Treekitkarnmongkol W; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Sankaran D; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Hurd MW; Ahmed Center for Pancreatic Cancer Research, MD Anderson Cancer Center, Houston, TX 77030, USA.
Putluri N; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L Duncan Cancer Center, Advanced Technology Core, Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, TX 77030, USA.
Maitra A; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.; Ahmed Center for Pancreatic Cancer Research, MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Haymaker C; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Sen S; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 27; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:: Journal Article
MeSH Terms:: Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/pathology
Extracellular Vesicles*/metabolism
Humans ; Matrix Metalloproteinase 9/metabolism ; Cytokines/metabolism ; Tumor Microenvironment ; Pancreatic Stellate Cells

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Skocz do pozycji: 18.

Tytuł:: Honokiol Acts as a Potent Anti-Fibrotic Agent in the Liver through Inhibition of TGF-β1/SMAD Signaling and Autophagy in Hepatic Stellate Cells.
Autorzy:: Kataoka S; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Umemura A; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Okuda K; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Taketani H; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Seko Y; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Nishikawa T; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Yamaguchi K; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Moriguchi M; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Kanbara Y; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita 564-0013, Japan.
Arbiser JL; Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Veterans Affairs Medical Center, Decatur, GA 30322, USA.
Shima T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita 564-0013, Japan.
Okanoue T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita 564-0013, Japan.
Itoh Y; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 12; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 12.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Tetrachloride Poisoning*/drug therapy
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Hepatic Stellate Cells*/metabolism
Hepatic Stellate Cells*/pathology
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/pathology
Autophagy/*drug effects
Biphenyl Compounds/*pharmacology
Lignans/*pharmacology
Liver/*metabolism
Signal Transduction/*drug effects
Smad Proteins/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Liver/pathology ; Male ; Mice

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Skocz do pozycji: 19.

Tytuł:: Proteomic Changes of Activated Hepatic Stellate Cells.
Autorzy:: Schinagl M; Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria.; Department of Pathology, Medical University of Graz, 8010 Graz, Austria.
Tomin T; Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria.
Gindlhuber J; Department of Pathology, Medical University of Graz, 8010 Graz, Austria.
Honeder S; Department of Pathology, Medical University of Graz, 8010 Graz, Austria.
Pfleger R; Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria.
Schittmayer M; Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria.
Trauner M; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, 1090 Vienna, Austria.
Birner-Gruenberger R; Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria.; Department of Pathology, Medical University of Graz, 8010 Graz, Austria.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 26; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 26.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Stellate Cells/*metabolism
Proteome/*analysis
Proteome/*metabolism
Serum Albumin, Bovine/*pharmacology
Animals ; Cattle ; Cell Movement ; Cell Proliferation ; Hepatic Stellate Cells/drug effects ; Humans ; Proteome/drug effects

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Skocz do pozycji: 20.

Tytuł:: Bone Morphogenetic Protein 13 Has Protumorigenic Effects on Hepatocellular Carcinoma Cells In Vitro.
Autorzy:: Kersten V; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, D-91054 Erlangen, Germany.
Seitz T; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, D-91054 Erlangen, Germany.
Sommer J; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, D-91054 Erlangen, Germany.
Thasler WE; Human Tissue and Cell Research-Services GmbH, Am Klopferspitz 19, D-82152 Planegg, Germany.
Bosserhoff A; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, D-91054 Erlangen, Germany.; Comprehensive Cancer Center (CCC) Erlangen-EMN, D-91054 Erlangen, Germany.
Hellerbrand C; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, D-91054 Erlangen, Germany.; Comprehensive Cancer Center (CCC) Erlangen-EMN, D-91054 Erlangen, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 04; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 04.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Hepatic Stellate Cells/metabolism ; Bone Morphogenetic Proteins/metabolism ; Cell Proliferation

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