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Tytuł :
Investigating the impact of reference assembly choice on genomic analyses in a cattle breed.
Autorzy :
Lloret-Villas A; Animal Genomics, ETH Zürich, Lindau, 8315, Switzerland. .
Bhati M; Animal Genomics, ETH Zürich, Lindau, 8315, Switzerland.
Kadri NK; Animal Genomics, ETH Zürich, Lindau, 8315, Switzerland.
Fries R; Chair of Animal Breeding, TU München, Freising-Weihenstephan, 85354, Germany.
Pausch H; Animal Genomics, ETH Zürich, Lindau, 8315, Switzerland.
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Źródło :
BMC genomics [BMC Genomics] 2021 May 19; Vol. 22 (1), pp. 363. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Genome*
Genome-Wide Association Study*
Animals ; Cattle/genetics ; Dogs ; Genomics ; Genotype ; Phenotype ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Estimating colocalization probability from limited summary statistics.
Autorzy :
King EA; AbbVie Genomics Research Center, North Chicago, IL, USA.
Dunbar F; AbbVie Genomics Research Center, North Chicago, IL, USA.
Davis JW; AbbVie Genomics Research Center, North Chicago, IL, USA.
Degner JF; AbbVie Genomics Research Center, North Chicago, IL, USA. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 May 17; Vol. 22 (1), pp. 254. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*
Quantitative Trait Loci*
Linkage Disequilibrium ; Multifactorial Inheritance ; Polymorphism, Single Nucleotide ; Probability
Czasopismo naukowe
Tytuł :
Genomic analyses and biological validation of candidate genes for rectal temperature as an indicator of heat stress in Holstein cattle.
Autorzy :
Luo H; Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China.
Li X; Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China.
Hu L; Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China.
Xu W; Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China.
Chu Q; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, 100097, Beijing, China.
Liu A; Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China; Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark.
Guo G; Beijing Sunlon Livestock Development Company Limited, 100029, Beijing, China.
Liu L; Beijing Dairy Cattle Center, 100192, Beijing, China.
Brito LF; Department of Animal Sciences, Purdue University, West Lafayette, IN 47907.
Wang Y; Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China. Electronic address: .
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Źródło :
Journal of dairy science [J Dairy Sci] 2021 Apr; Vol. 104 (4), pp. 4441-4451. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*/veterinary
Leukocytes, Mononuclear*
Animals ; Cattle/genetics ; Female ; Genomics ; Heat-Shock Response/genetics ; Polymorphism, Single Nucleotide ; Temperature
Czasopismo naukowe
Tytuł :
Genomic risk score provides predictive performance for type 2 diabetes in the UK biobank.
Autorzy :
Chen X; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China.
Liu C; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China.
Si S; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China.
Li Y; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China.
Li W; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China.
Yuan T; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China.
Xue F; Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, No.44 Wenhuaxi Road, Jinan, 250012, People's Republic of China. .; Institute for Medical Dataology, Shandong University, No.12550 Erhuandong Road, Jinan, 250002, People's Republic of China. .
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Źródło :
Acta diabetologica [Acta Diabetol] 2021 Apr; Vol. 58 (4), pp. 467-474. Date of Electronic Publication: 2021 Jan 03.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Genome-Wide Association Study*/methods
Genome-Wide Association Study*/statistics & numerical data
Biological Specimen Banks/*statistics & numerical data
Diabetes Mellitus, Type 2/*diagnosis
Diabetes Mellitus, Type 2/*genetics
Adult ; Aged ; Diabetes Mellitus, Type 2/epidemiology ; Early Diagnosis ; Female ; Genetic Predisposition to Disease ; Genomics/methods ; Genomics/statistics & numerical data ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Proportional Hazards Models ; Risk Factors ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł :
Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.
Autorzy :
Hu Y; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Bien SA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Nishimura KK; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Haessler J; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Hodonsky CJ; Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Baldassari AR; Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Highland HM; Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Preuss M; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sitlani CM; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
Wojcik GL; Stanford University School of Medicine, Stanford, CA, USA.
Tao R; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.; The Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Graff M; Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Huckins LM; Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sun Q; Department of Biostatistics, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Chen MH; The Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
Mousas A; Montreal Heart Institute, Montreal, Quebec, Canada.
Auer PL; School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Lettre G; Montreal Heart Institute, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
Kooperberg C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .
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Corporate Authors :
Blood Cell Consortium
Źródło :
BMC genomics [BMC Genomics] 2021 Jun 09; Vol. 22 (1), pp. 432. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*
Polymorphism, Single Nucleotide*
Genetic Predisposition to Disease ; Genomics ; Humans ; Leukocytes ; Phenotype
Czasopismo naukowe
Tytuł :
Genome-wide association analysis of adaptation to oxygen stress in Nile tilapia (Oreochromis niloticus).
Autorzy :
Yu X; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands. .
Megens HJ; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands.
Mengistu SB; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands.; School of Animal and Range Sciences, College of Agriculture, Hawassa University, Hawassa, Ethiopia.
Bastiaansen JWM; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands.
Mulder HA; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands.
Benzie JAH; WorldFish Centre, Jalan Batu Maung, Bayan Lepas, Penang, Malaysia.; School of Biological Earth and Environmental Sciences, University College Cork, Cork, Ireland.
Groenen MAM; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands.
Komen H; Wageningen University & Research, Animal Breeding and Genomics, Wageningen, The Netherlands.
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Źródło :
BMC genomics [BMC Genomics] 2021 Jun 09; Vol. 22 (1), pp. 426. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Cichlids*/genetics
Genome-Wide Association Study*
Animals ; Genetic Linkage ; Genotype ; Oxygen
Czasopismo naukowe
Tytuł :
Genome-wide association study and transcriptome analysis discover new genes for bacterial leaf blight resistance in rice (Oryza sativa L.).
Autorzy :
Shu X; College of Agronomy, Sichuan Agricultural University, Chengdu, China.; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.; State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Chengdu, China.
Wang A; College of Agronomy, Sichuan Agricultural University, Chengdu, China.; State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Chengdu, China.
Jiang B; College of Life Science and Technology, Yangtz Normal University, Chongqing, China.
Jiang Y; College of Agronomy, Sichuan Agricultural University, Chengdu, China.; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.; State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Chengdu, China.
Xiang X; College of Agronomy, Sichuan Agricultural University, Chengdu, China.; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.; State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Chengdu, China.
Yi X; College of Agronomy, Sichuan Agricultural University, Chengdu, China.
Li S; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Deng Q; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Wang S; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Zhu J; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Liang Y; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Liu H; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Zou T; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Wang L; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Li P; Rice Research Institute of Sichuan Agricultural University, Chengdu, China.
Zheng A; College of Agronomy, Sichuan Agricultural University, Chengdu, China. .; State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Chengdu, China. .
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Źródło :
BMC plant biology [BMC Plant Biol] 2021 Jun 03; Vol. 21 (1), pp. 255. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Plant*/immunology
Genetic Predisposition to Disease*
Genome-Wide Association Study*
Transcriptome*
Oryza/*genetics
Plant Diseases/*microbiology
Genotype ; Haplotypes ; Plant Diseases/genetics ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci
Czasopismo naukowe
Tytuł :
Mendelian randomization studies of brain MRI yield insights into the pathogenesis of neuropsychiatric disorders.
Autorzy :
Song W; Shanghai Mental Health Center, School of Biomedical Engineering, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, 200030, Shanghai, China.
Qian W; Shanghai Mental Health Center, School of Biomedical Engineering, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, 200030, Shanghai, China.
Wang W; Shanghai Mental Health Center, School of Biomedical Engineering, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, 200030, Shanghai, China.; Shanghai Key Laboratory of Psychotic Disorders, 200030, Shanghai, China.
Yu S; Shanghai Mental Health Center, School of Biomedical Engineering, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, 200030, Shanghai, China.; Shanghai Key Laboratory of Psychotic Disorders, 200030, Shanghai, China.
Lin GN; Shanghai Mental Health Center, School of Biomedical Engineering, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, 200030, Shanghai, China. .; Shanghai Key Laboratory of Psychotic Disorders, 200030, Shanghai, China. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Jun 02; Vol. 22 (Suppl 3), pp. 342. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
Diffusion Tensor Imaging*
Genome-Wide Association Study*
Brain/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Mendelian Randomization Analysis ; Neuroimaging
Czasopismo naukowe
Tytuł :
Thoracic and abdominal aortic aneurysms: exploring their contrast and genetic associations.
Autorzy :
Khashkhusha A; University of Liverpool, Brownlow Hill, Liverpool, UK.
Munir W; Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Bashir M; Department of Vascular Surgery, Royal Blackburn Teaching Hospital, Blackburn, UK - .
Idhrees M; Institute of Cardiac and Aortic Disorders, SRM Institutes for Medical Science (SIMS Hospitals), Chennai, India.
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Źródło :
The Journal of cardiovascular surgery [J Cardiovasc Surg (Torino)] 2021 Jun; Vol. 62 (3), pp. 211-219. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genome-Wide Association Study*
Aortic Aneurysm, Abdominal/*genetics
Aortic Aneurysm, Thoracic/*genetics
Humans ; Risk Factors
Czasopismo naukowe
Tytuł :
Assessment of genetic risk of type 2 diabetes among Pakistanis based on GWAS-implicated loci.
Autorzy :
Sabiha B; Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), H-12, Islamabad, Pakistan.
Bhatti A; Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), H-12, Islamabad, Pakistan. Electronic address: .
Fan KH; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA.
John P; Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), H-12, Islamabad, Pakistan.
Aslam MM; Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), H-12, Islamabad, Pakistan; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA.
Ali J; Center for Genome Sciences, Rehman Medical College, Phase-V, Hayatabad, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Feingold E; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA.
Demirci FY; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA.
Kamboh MI; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA.
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Źródło :
Gene [Gene] 2021 May 30; Vol. 783, pp. 145563. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*
Diabetes Mellitus, Type 2/*genetics
Female ; Genetic Predisposition to Disease ; Genotyping Techniques ; Humans ; Male ; Middle Aged ; Pakistan ; Polymorphism, Single Nucleotide ; Risk Assessment
Czasopismo naukowe
Tytuł :
Genetics of symptom remission in outpatients with COVID-19.
Autorzy :
Dubé MP; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada. .; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada. .; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada. .
Lemaçon A; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.
Barhdadi A; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Lemieux Perreault LP; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Oussaïd E; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Asselin G; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Provost S; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Sun M; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.
Sandoval J; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Legault MA; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.
Mongrain I; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Dubois A; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Valois D; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Dedelis E; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Lousky J; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Choi J; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.
Goulet E; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Savard C; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Chicoine LM; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Cossette M; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Montreal Health Innovations Coordinating Centre, Montreal, Canada.
Chabot-Blanchet M; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Montreal Health Innovations Coordinating Centre, Montreal, Canada.
Guertin MC; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Montreal Health Innovations Coordinating Centre, Montreal, Canada.
de Denus S; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Centre, Montreal, Canada.; Faculty of Pharmacy, Université de Montréal, Montreal, Canada.
Bouabdallaoui N; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Marchand R; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Bassevitch Z; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Montreal Health Innovations Coordinating Centre, Montreal, Canada.
Nozza A; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Montreal Health Innovations Coordinating Centre, Montreal, Canada.
Gaudet D; Ecogene-21 and Department of Medicine, Université de Montréal, Chicoutimi, Canada.
L'Allier PL; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Hussin J; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.
Boivin G; Centre Hospitalier de l'Université Laval, Quebec City, Canada.
Busseuil D; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada.
Tardif JC; Montreal Heart Institute, 5000 Belanger Street, Montreal, H1T 1C8, Canada. .; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada. .
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Źródło :
Scientific reports [Sci Rep] 2021 May 25; Vol. 11 (1), pp. 10847. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome-Wide Association Study*
COVID-19/*drug therapy
Colchicine/*therapeutic use
Adult ; COVID-19/genetics ; COVID-19/pathology ; COVID-19/virology ; Chromosomes, Human, Pair 5/genetics ; Chromosomes, Human, Pair 9/genetics ; Double-Blind Method ; Female ; Gene Frequency ; Genotype ; Humans ; Male ; Middle Aged ; Outpatients ; Placebo Effect ; Proportional Hazards Models ; Remission Induction ; Risk Factors ; SARS-CoV-2/isolation & purification ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Genome-wide association analysis reveals that EDNRB2 causes a dose-dependent loss of pigmentation in ducks.
Autorzy :
Xi Y; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Xu Q; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Huang Q; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Ma S; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Wang Y; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Han C; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Zhang R; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Wang J; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China.
Liu H; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China. .
Li L; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People's Republic of China. .
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Źródło :
BMC genomics [BMC Genomics] 2021 May 25; Vol. 22 (1), pp. 381. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Ducks*/genetics
Genome-Wide Association Study*
Animals ; Phenotype ; Pigmentation/genetics ; Polymorphism, Single Nucleotide ; Receptor, Endothelin B/genetics
Czasopismo naukowe
Tytuł :
PCAmatchR: a flexible R package for optimal case-control matching using weighted principal components.
Autorzy :
Brown DW; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA.; Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, MD 20850, USA.
Myers TA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA.
Machiela MJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20850, USA.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 May 23; Vol. 37 (8), pp. 1178-1181.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Genome-Wide Association Study*
Software*
Case-Control Studies ; Genomics ; Principal Component Analysis
Czasopismo naukowe
Tytuł :
TreeMap: a structured approach to fine mapping of eQTL variants.
Autorzy :
Liu L; College of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA.; Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
Chandrashekar P; College of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA.; Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
Zeng B; Center for Integrative Genomics, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Sanderford MD; Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122, USA.
Kumar S; Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA 19122, USA.; Department of Biology, Temple University, Philadelphia, PA 19122, USA.; Center for Excellence in Genome Medicine and Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Gibson G; Center for Integrative Genomics, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 May 23; Vol. 37 (8), pp. 1125-1134.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome-Wide Association Study*
Quantitative Trait Loci*/genetics
Chromosome Mapping ; Colon ; Gene Expression ; Hippocampus ; Humans ; Linkage Disequilibrium ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Modeling regulatory network topology improves genome-wide analyses of complex human traits.
Autorzy :
Zhu X; Department of Statistics, The Pennsylvania State University, University Park, PA, 16802, USA. .; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, 16802, USA. .; Department of Statistics, Stanford University, Stanford, CA, 94305, USA. .
Duren Z; Department of Statistics, Stanford University, Stanford, CA, 94305, USA.; Center for Human Genetics, Department of Genetics and Biochemistry, Clemson University, Greenwood, SC, 29646, USA.
Wong WH; Department of Statistics, Stanford University, Stanford, CA, 94305, USA. .; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, 94305, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2851. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Models, Genetic*
Genome-Wide Association Study/*methods
Multifactorial Inheritance/*genetics
Algorithms ; Bayes Theorem ; Computer Simulation ; Data Mining ; Genome, Human ; Genome-Wide Association Study/statistics & numerical data ; Humans ; Polymorphism, Single Nucleotide ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
How imputation can mitigate SNP ascertainment Bias.
Autorzy :
Geibel J; Department of Animal Sciences, Animal Breeding and Genetics Group, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany. .; Center for Integrated Breeding Research, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany. .
Reimer C; Department of Animal Sciences, Animal Breeding and Genetics Group, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.; Center for Integrated Breeding Research, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.
Pook T; Department of Animal Sciences, Animal Breeding and Genetics Group, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.; Center for Integrated Breeding Research, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.
Weigend S; Center for Integrated Breeding Research, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.; Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Höltystrasse 10, 31535, Neustadt-Mariensee, Germany.
Weigend A; Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Höltystrasse 10, 31535, Neustadt-Mariensee, Germany.
Simianer H; Department of Animal Sciences, Animal Breeding and Genetics Group, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.; Center for Integrated Breeding Research, University of Goettingen, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.
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Źródło :
BMC genomics [BMC Genomics] 2021 May 12; Vol. 22 (1), pp. 340. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*
Polymorphism, Single Nucleotide*
Animals ; Chickens/genetics ; Gene Frequency ; Genotype
Czasopismo naukowe
Tytuł :
Genome-wide association study reveals novel loci associated with feeding behavior in Pekin ducks.
Autorzy :
Li GS; National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA; College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Zhu F; National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA; College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Zhang F; National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA; College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Yang FX; Beijing Golden Star Inc, Beijing, 100076, China.
Hao JP; Beijing Golden Star Inc, Beijing, 100076, China.
Hou ZC; National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA; College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. .
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Źródło :
BMC genomics [BMC Genomics] 2021 May 08; Vol. 22 (1), pp. 334. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
Ducks*/genetics
Genome-Wide Association Study*
Animals ; Feeding Behavior ; Genotype ; Phenotype
Czasopismo naukowe
Tytuł :
Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs.
Autorzy :
Qiu Y; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Ding R; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.; Guangdong Wens Breeding Swine Technology Co., Ltd., Yunfu, Guangdong, 527400, People's Republic of China.
Zhuang Z; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Wu J; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Yang M; Guangdong Wens Breeding Swine Technology Co., Ltd., Yunfu, Guangdong, 527400, People's Republic of China.
Zhou S; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Ye Y; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Geng Q; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Xu Z; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.; Lingnan Guangdong Laboratory of Modern Agriculture, Guangzhou, 510642, People's Republic of China.
Huang S; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.
Cai G; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China.; Guangdong Wens Breeding Swine Technology Co., Ltd., Yunfu, Guangdong, 527400, People's Republic of China.; Lingnan Guangdong Laboratory of Modern Agriculture, Guangzhou, 510642, People's Republic of China.
Wu Z; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China. .; Guangdong Wens Breeding Swine Technology Co., Ltd., Yunfu, Guangdong, 527400, People's Republic of China. .; Lingnan Guangdong Laboratory of Modern Agriculture, Guangzhou, 510642, People's Republic of China. .
Yang J; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, People's Republic of China. .; Lingnan Guangdong Laboratory of Modern Agriculture, Guangzhou, 510642, People's Republic of China. .
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Źródło :
BMC genomics [BMC Genomics] 2021 May 08; Vol. 22 (1), pp. 332. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Copy Number Variations*
Genome-Wide Association Study*
Animals ; Canada ; Genome ; Polymorphism, Single Nucleotide ; Sus scrofa/genetics ; Swine/genetics
Czasopismo naukowe
Tytuł :
A new method for exploring gene-gene and gene-environment interactions in GWAS with tree ensemble methods and SHAP values.
Autorzy :
Johnsen PV; SINTEF DIGITAL, Forskningsveien 1, 0373, Oslo, Norway. .; Department of Mathematical Sciences, Norwegian University of Science and Technology, A. Getz vei 1, 7491, Trondheim, Norway. .
Riemer-Sørensen S; SINTEF DIGITAL, Forskningsveien 1, 0373, Oslo, Norway.
DeWan AT; Department of Chronic Disease Epidemiology and Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, 1 Church Street, New Haven, CT, 06510, USA.; Gemini Center for Sepsis Research, Department of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Prinsesse Kristinas gate 3, 7030, Trondheim, Norway.
Cahill ME; Department of Chronic Disease Epidemiology and Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, 1 Church Street, New Haven, CT, 06510, USA.
Langaas M; Department of Mathematical Sciences, Norwegian University of Science and Technology, A. Getz vei 1, 7491, Trondheim, Norway.
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 May 04; Vol. 22 (1), pp. 230. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Gene-Environment Interaction*
Genome-Wide Association Study*
Algorithms ; Polymorphism, Single Nucleotide ; Trees
Czasopismo naukowe
Tytuł :
A fast wavelet-based functional association analysis replicates several susceptibility loci for birth weight in a Norwegian population.
Autorzy :
Denault WRP; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway. .; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. .; Centre for Fertility and Health (CeFH), Norwegian Institute of Public Health, Oslo, Norway. .
Romanowska J; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; Centre for Fertility and Health (CeFH), Norwegian Institute of Public Health, Oslo, Norway.
Helgeland Ø; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
Jacobsson B; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway.; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Gjessing HK; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; Centre for Fertility and Health (CeFH), Norwegian Institute of Public Health, Oslo, Norway.
Jugessur A; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway.; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; Centre for Fertility and Health (CeFH), Norwegian Institute of Public Health, Oslo, Norway.
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Źródło :
BMC genomics [BMC Genomics] 2021 May 02; Vol. 22 (1), pp. 321. Date of Electronic Publication: 2021 May 02.
Typ publikacji :
Journal Article
MeSH Terms :
Genome-Wide Association Study*
Quantitative Trait Loci*
Birth Weight/genetics ; Child ; Genotype ; Humans ; Polymorphism, Single Nucleotide
Czasopismo naukowe

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