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Wyszukujesz frazę ""synaptophysin"" wg kryterium: Temat


Tytuł :
Synaptophysin controls synaptobrevin-II retrieval via a cryptic C-terminal interaction site.
Autorzy :
Harper CB; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK; Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK.
Blumrich EM; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK; Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK.
Cousin MA; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK; Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh, Scotland, EH8 9XD, UK. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100266. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurons/*metabolism
Synaptic Vesicles/*genetics
Synaptophysin/*genetics
Vesicle-Associated Membrane Protein 2/*genetics
Endocytosis/genetics ; Gene Knockout Techniques ; Hippocampus/metabolism ; Hippocampus/pathology ; Neurons/chemistry ; Primary Cell Culture ; SNARE Proteins/genetics ; Synaptic Transmission/genetics ; Synaptophysin/chemistry ; Synaptosomes/chemistry ; Synaptosomes/metabolism
Czasopismo naukowe
Tytuł :
Application of INSM1 in Diagnosis and Grading of Laryngeal Neuroendocrine Carcinoma.
Autorzy :
Yuan C; Department of Pathology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.
Jiao F; Department of Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Zhai C; Department of Pathology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.
Zhang J; Department of Pathology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.
Wang S; Department of Pathology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.
Zhu L; Department of Pathology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.
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Źródło :
The Laryngoscope [Laryngoscope] 2021 Oct; Vol. 131 (10), pp. E2662-E2668. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*analysis
Laryngeal Neoplasms/*pathology
Neuroendocrine Tumors/*pathology
Repressor Proteins/*analysis
Aged ; CD56 Antigen/analysis ; Chromogranins/analysis ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Retrospective Studies ; Sensitivity and Specificity ; Synaptophysin/analysis
Czasopismo naukowe
Tytuł :
Immunophenotypic Characterization of Germ Cell Tumor-Derived Primitive Neuroectodermal Tumors: Evidence for Frequent Neuronal and/or Glial Differentiation.
Autorzy :
Magers MJ; From IHA Pathology, Department of Pathology and Laboratory Medicine, Ann Arbor, Michigan (Magers).
Perrino CM; The Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island (Perrino).
Ulbright TM; The Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis (Ulbright, Idrees).
Idrees MT; The Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis (Ulbright, Idrees).
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Źródło :
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2021 Aug 01; Vol. 145 (8), pp. 953-959.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Immunohistochemistry*
Biomarkers, Tumor/*analysis
Neoplasms, Germ Cell and Embryonal/*chemistry
Neuroectodermal Tumors, Primitive, Peripheral/*chemistry
Neuroglia/*chemistry
Neurons/*chemistry
Testicular Neoplasms/*chemistry
Adolescent ; Adult ; Chromogranin A/analysis ; Glial Fibrillary Acidic Protein/analysis ; Humans ; Male ; Middle Aged ; Neoplasms, Germ Cell and Embryonal/pathology ; Neoplasms, Germ Cell and Embryonal/surgery ; Neuroectodermal Tumors, Primitive, Peripheral/pathology ; Neuroectodermal Tumors, Primitive, Peripheral/surgery ; Neuroglia/pathology ; Neurons/pathology ; Phenotype ; Predictive Value of Tests ; S100 Proteins/analysis ; SOXC Transcription Factors/analysis ; Synaptophysin/analysis ; Testicular Neoplasms/pathology ; Testicular Neoplasms/surgery ; Young Adult
Czasopismo naukowe
Tytuł :
Serum SYPL1 is a promising diagnostic biomarker for colorectal cancer.
Autorzy :
Liu L; Medical Research Center, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China.
He Q; Department of Clinical Laboratory, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610031, China.
Li Y; Department of General Surgery, No. 42 Hospital of PLA, Leshan, Sichuan 614000, China.
Zhang B; Department of Clinical Laboratory, Nanchong Central Hospital, Nanchong, Sichuan 637000, China.
Sun X; Department of Gastroenterology, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China.
Shan J; Department of Gastroenterology, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China.
Pan B; Medical Research Center, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China.
Zhang T; Medical Research Center, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China.
Zhao Z; Medical Research Center, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China.
Song X; Department of Clinical Laboratory, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610031, China. Electronic address: .
Guo Y; Medical Research Center, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan 610031, China. Electronic address: .
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Źródło :
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2020 Oct; Vol. 509, pp. 36-42. Date of Electronic Publication: 2020 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
Adenoma*/diagnosis
Colonic Neoplasms*
Colorectal Neoplasms*/diagnosis
Synaptophysin*/blood
Biomarkers, Tumor/genetics ; CA-19-9 Antigen ; Carcinoembryonic Antigen ; Humans
Czasopismo naukowe
Tytuł :
A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders.
Autorzy :
Levine AJ; Department of Neurology, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA. .
Soontornniyomkij V; Department of Psychiatry, University of California San Diego School of Medicine, San Diego, CA, USA.
Masliah E; Departments of Neurosciences and Pathology, University of California San Diego School of Medicine, San Diego, CA, USA.
Sinsheimer JS; Departments of Human Genetics and Computational Biology, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA.; Department of Biostatistics, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Ji SS; Department of Biostatistics, UCLA Fielding School of Public Health, Los Angeles, CA, USA.
Horvath S; Department of Biostatistics, UCLA Fielding School of Public Health, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA.
Singer EJ; Department of Neurology, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA.
Kallianpur A; Department of Molecular Medicine, Genomic Medicine, Medicine, & Pediatrics, Cleveland Clinic/Lerner Research Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
Moore DJ; Department of Psychiatry, University of California San Diego School of Medicine, San Diego, CA, USA.
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Źródło :
Journal of neurovirology [J Neurovirol] 2020 Aug; Vol. 26 (4), pp. 496-508. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cognitive Dysfunction/*genetics
Dendrites/*pathology
HIV Infections/*genetics
Microtubule-Associated Proteins/*genetics
Synapses/*pathology
Synaptophysin/*genetics
Adult ; Cognitive Dysfunction/complications ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/pathology ; Cytokines/genetics ; Dendrites/genetics ; Dendrites/metabolism ; Female ; Frontal Lobe/metabolism ; Frontal Lobe/pathology ; Gene Expression ; Genotype ; HIV Infections/complications ; HIV Infections/metabolism ; HIV Infections/pathology ; Humans ; Longitudinal Studies ; Male ; Microtubule-Associated Proteins/metabolism ; Middle Aged ; Neuropsychological Tests ; Phenotype ; Polymorphism, Genetic ; Presynaptic Terminals/metabolism ; Presynaptic Terminals/pathology ; Synapses/genetics ; Synapses/metabolism ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Melatonin improves memory defects in a mouse model of multiple sclerosis by up-regulating cAMP-response element-binding protein and synapse-associated proteins in the prefrontal cortex.
Autorzy :
Alghamdi BS; Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.; Neuroscience Unit, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saud Arabia.; Pre-Clinical Research Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
AboTaleb HA; Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
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Źródło :
Journal of integrative neuroscience [J Integr Neurosci] 2020 Jun 30; Vol. 19 (2), pp. 229-237.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclic AMP Response Element-Binding Protein/*drug effects
Disks Large Homolog 4 Protein/*drug effects
Melatonin/*pharmacology
Memory Disorders/*drug therapy
Multiple Sclerosis/*complications
Neuroprotective Agents/*pharmacology
Prefrontal Cortex/*drug effects
Synaptophysin/*drug effects
Animals ; Behavior, Animal/drug effects ; Cuprizone/administration & dosage ; Cyclic AMP Response Element-Binding Protein/metabolism ; Disease Models, Animal ; Disks Large Homolog 4 Protein/metabolism ; Gene Expression/drug effects ; Melatonin/administration & dosage ; Memory Disorders/etiology ; Memory Disorders/metabolism ; Mice ; Monoamine Oxidase Inhibitors/administration & dosage ; Neuroprotective Agents/administration & dosage ; Prefrontal Cortex/metabolism ; Recognition, Psychology/drug effects ; Spatial Learning/drug effects ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Long-Term Social Isolation Reduces Expression of the BDNF Precursor and Prolyl Endopeptidase in the Rat Brain.
Autorzy :
Shirenova SD; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, 125315, Russia. .
Khlebnikova NN; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, 125315, Russia.
Krupina NA; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, 125315, Russia.
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Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2021 Jun; Vol. 86 (6), pp. 704-715.
Typ publikacji :
Journal Article
MeSH Terms :
Social Isolation*
Brain/*metabolism
Brain-Derived Neurotrophic Factor/*genetics
Prolyl Oligopeptidases/*genetics
Stress, Psychological/*metabolism
Animals ; Female ; Frontal Lobe/metabolism ; Gene Expression Regulation ; Hippocampus/metabolism ; Male ; Neuronal Plasticity ; Rats ; Rats, Wistar ; Stress, Psychological/enzymology ; Stress, Psychological/genetics ; Synaptophysin/genetics
Czasopismo naukowe
Tytuł :
Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples.
Autorzy :
Kriegsmann K; Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
Zgorzelski C; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Muley T; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.; Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
Christopoulos P; Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany.; Department of Thoracic Oncology, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
Thomas M; Department of Thoracic Oncology, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
Winter H; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.; Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany.; Department of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
Eichhorn M; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.; Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany.; Department of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
Eichhorn F; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.; Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany.; Department of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
von Winterfeld M; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Herpel E; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Goeppert B; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.
Stenzinger A; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.
Herth FJF; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.; Department of Pneumology and Critical Care Medicine, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
Warth A; Institute of Pathology, Cytopathology, and Molecular Pathology, UEGP MVZ, Gießen, Wetzlar, Limburg, Germany.
Kriegsmann M; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany. .; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany. .; Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany. .
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Źródło :
BMC cancer [BMC Cancer] 2021 May 01; Vol. 21 (1), pp. 486. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*chemistry
CD56 Antigen/*analysis
Carcinoma, Squamous Cell/*chemistry
Chromogranins/*analysis
Lung Neoplasms/*chemistry
Synaptophysin/*analysis
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Analysis of Variance ; Biomarkers, Tumor/analysis ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Cell Differentiation ; Disease-Free Survival ; Female ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Retrospective Studies ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Modulating electrophysiology of motor neural networks via optogenetic stimulation during neurogenesis and synaptogenesis.
Autorzy :
Pagan-Diaz GJ; Department of Bioengineering, University of Illinois, Urbana-Champaign, Engineering Hall, 1308 W Green St, Urbana, IL, 61801, USA.; Nick Holonyak Micro and Nanotechnology Lab, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.
Drnevich J; High Performance Biological Computing and the Carver Biotechnology Center, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.
Ramos-Cruz KP; Department of Bioengineering, University of Illinois, Urbana-Champaign, Engineering Hall, 1308 W Green St, Urbana, IL, 61801, USA.; Nick Holonyak Micro and Nanotechnology Lab, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.
Sam R; Nick Holonyak Micro and Nanotechnology Lab, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.; School of Molecular and Cellular Biology, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.
Sengupta P; Department of Bioengineering, University of Illinois, Urbana-Champaign, Engineering Hall, 1308 W Green St, Urbana, IL, 61801, USA.; Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.; Program in Neuroscience, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA.; Richard and Loan Hill Department of Bioengineering, University of Illinois, Urbana-Champaign, Chicago, 60607, USA.
Bashir R; Department of Bioengineering, University of Illinois, Urbana-Champaign, Engineering Hall, 1308 W Green St, Urbana, IL, 61801, USA. .; Nick Holonyak Micro and Nanotechnology Lab, University of Illinois, Urbana-Champaign, Urbana, IL, 61801, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 27; Vol. 10 (1), pp. 12460. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Motor Neurons/*metabolism
Nerve Net/*metabolism
Synapses/*metabolism
Synaptophysin/*metabolism
Action Potentials ; Animals ; Channelrhodopsins/genetics ; Channelrhodopsins/metabolism ; Electrophysiology ; Embryonic Stem Cells/chemistry ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism ; Mice ; Mice, Transgenic ; Motor Neurons/chemistry ; Motor Neurons/cytology ; Neurites/chemistry ; Neurites/metabolism ; Neurogenesis ; Optogenetics ; Synapses/chemistry ; Synapses/genetics ; Synaptophysin/genetics
Czasopismo naukowe
Tytuł :
Immunohistochemical Characteristics of the Human Carotid Body in the Antenatal and Postnatal Periods of Development.
Autorzy :
Otlyga D; Research Institute of Human Morphology, 117418 Moscow, Russia.
Tsvetkova E; Research Institute of Human Morphology, 117418 Moscow, Russia.
Junemann O; Research Institute of Human Morphology, 117418 Moscow, Russia.
Saveliev S; Research Institute of Human Morphology, 117418 Moscow, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 30; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Carotid Body/*growth & development
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Carotid Body/embryology ; Carotid Body/metabolism ; Child ; Child, Preschool ; Glial Fibrillary Acidic Protein/metabolism ; Humans ; Infant ; Infant, Newborn ; Middle Aged ; Synaptophysin/metabolism ; Tubulin/metabolism ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
Hypoglycemia and seizures associated with canine primary hepatic neuroendocrine carcinoma.
Autorzy :
Dorn AR; Midwestern University College of Veterinary Medicine, Glendale, AZ, USA.
Brower A; Midwestern University College of Veterinary Medicine, Glendale, AZ, USA.
Turner H; Midwestern University College of Veterinary Medicine, Glendale, AZ, USA.
Lapa K; BluePearl Specialty and Emergency Hospital, Phoenix, AZ, USA.
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Źródło :
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2021 Jul; Vol. 33 (4), pp. 749-752. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Carcinoma, Neuroendocrine/*veterinary
Dog Diseases/*diagnosis
Hypoglycemia/*veterinary
Liver Neoplasms/*veterinary
Seizures/*veterinary
Animals ; Carcinoma, Neuroendocrine/complications ; Carcinoma, Neuroendocrine/pathology ; Dog Diseases/etiology ; Dog Diseases/pathology ; Dogs ; Hypoglycemia/complications ; Immunohistochemistry ; Liver Neoplasms/complications ; Liver Neoplasms/pathology ; Male ; Seizures/complications ; Synaptophysin
Czasopismo naukowe
Tytuł :
Environmental enrichment applied with sensory components prevents age-related decline in synaptic dynamics: Evidence from the zebrafish model organism.
Autorzy :
Karoglu-Eravsar ET; Interdisciplinary Program in Neuroscience, Aysel Sabuncu Brain Research Center, Bilkent University, Ankara, Turkey; National Nanotechnology Research Center (UNAM), Bilkent University, Ankara, Turkey; Department of Molecular Biology and Genetics, Zebrafish Facility, Bilkent University, Ankara, Turkey; Department of Psychology, Selcuk University, Konya, Turkey.
Tuz-Sasik MU; Interdisciplinary Program in Neuroscience, Aysel Sabuncu Brain Research Center, Bilkent University, Ankara, Turkey; National Nanotechnology Research Center (UNAM), Bilkent University, Ankara, Turkey; Department of Molecular Biology and Genetics, Zebrafish Facility, Bilkent University, Ankara, Turkey.
Adams MM; Interdisciplinary Program in Neuroscience, Aysel Sabuncu Brain Research Center, Bilkent University, Ankara, Turkey; National Nanotechnology Research Center (UNAM), Bilkent University, Ankara, Turkey; Department of Molecular Biology and Genetics, Zebrafish Facility, Bilkent University, Ankara, Turkey; Department of Psychology, Bilkent University, Ankara, Turkey. Electronic address: .
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Źródło :
Experimental gerontology [Exp Gerontol] 2021 Jul 01; Vol. 149, pp. 111346. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cognitive Dysfunction*
Zebrafish*
Aged ; Aging ; Animals ; Environment ; Humans ; Middle Aged ; Synaptophysin
Czasopismo naukowe
Tytuł :
Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity.
Autorzy :
Xu C; Department of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Zhang M; Department of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Zu L; Department of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Zhang P; Department of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Sun L; Gordon F. Derner School of Psychology, Adelphi University, New York, NY 11530-0701, USA.
Liu X; Department of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Fang M; Department of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
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Źródło :
Aging [Aging (Albany NY)] 2021 Jun 09; Vol. 13 (11), pp. 15569-15579. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, Immediate-Early*
Neuronal Plasticity/*genetics
Receptors, Glutamate/*metabolism
Repressor Proteins/*metabolism
Amyloid beta-Peptides/metabolism ; Animals ; Base Sequence ; Cell Line, Tumor ; Cells, Cultured ; Cytoskeletal Proteins/metabolism ; Disks Large Homolog 4 Protein/metabolism ; Gene Knockdown Techniques ; Hippocampus/cytology ; Humans ; Mice, Inbred C57BL ; Nerve Tissue Proteins/metabolism ; Neurons/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Synapses/metabolism ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice.
Autorzy :
Jiang Y; College of Medicine, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials for Ministry of Education, Nankai University, Tianjin, 300071, China.
Li K; College of Medicine, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials for Ministry of Education, Nankai University, Tianjin, 300071, China.
Li X; College of Medicine, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials for Ministry of Education, Nankai University, Tianjin, 300071, China.
Xu L; College of Medicine, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials for Ministry of Education, Nankai University, Tianjin, 300071, China.
Yang Z; College of Medicine, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials for Ministry of Education, Nankai University, Tianjin, 300071, China. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 May 25; Vol. 341, pp. 109452. Date of Electronic Publication: 2021 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Brain/*drug effects
Butyric Acid/*pharmacology
Inflammation/*drug therapy
Neuronal Plasticity/*drug effects
Alzheimer Disease/pathology ; Amyloid beta-Peptides/metabolism ; Animals ; Brain/metabolism ; Brain/pathology ; Cognitive Dysfunction/drug therapy ; Disease Models, Animal ; Disks Large Homolog 4 Protein/metabolism ; Inflammation/pathology ; Long-Term Potentiation/drug effects ; Mice, Transgenic ; Microglia/drug effects ; Microglia/pathology ; Morris Water Maze Test ; Neuronal Plasticity/physiology ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Xuesaitong exerts long-term neuroprotection for stroke recovery by inhibiting the ROCKII pathway, in vitro and in vivo.
Autorzy :
Zhou D; Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Cen K; Department of Stomatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Liu W; Department of Rehabilitation, Beijing Children's Hospital, Capital Medical University, 100045, Beijing, China. Electronic address: .
Liu F; Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Liu R; Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Sun Y; Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Zhao Y; Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Chang J; Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
Zhu L; Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China; Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, 100700, Beijing, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 May 23; Vol. 272, pp. 113943. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal/*pharmacology
Infarction, Middle Cerebral Artery/*drug therapy
Neuroprotective Agents/*pharmacology
Saponins/*pharmacology
rho-Associated Kinases/*antagonists & inhibitors
Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Disease Models, Animal ; Disks Large Homolog 4 Protein/metabolism ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Infarction, Middle Cerebral Artery/metabolism ; Infarction, Middle Cerebral Artery/pathology ; Male ; Neuroprotection/drug effects ; Neuroprotective Agents/therapeutic use ; Nogo Proteins/antagonists & inhibitors ; Nogo Proteins/genetics ; Nogo Proteins/metabolism ; Panax notoginseng/chemistry ; Rats, Sprague-Dawley ; Reperfusion Injury/drug therapy ; Saponins/therapeutic use ; Signal Transduction/drug effects ; Stroke/drug therapy ; Synaptophysin/metabolism ; Time Factors ; rho GTP-Binding Proteins/genetics ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Clinicopathologic Characterization of Epithelioid Hemangioendothelioma in a Series of 62 Cases: A Proposal of Risk Stratification and Identification of a Synaptophysin-positive Aggressive Subset.
Autorzy :
Shibayama T; Departments of Diagnostic Pathology.
Makise N; Department of Pathology, the University of Tokyo Hospital.
Motoi T; Departments of Pathology.
Mori T; Departments of Diagnostic Pathology.
Hiraoka N; Departments of Diagnostic Pathology.
Yonemori K; Breast and Medical Oncology.; Rare Cancer Center, National Cancer Center Hospital.
Watanabe SI; Thoracic Surgery.
Esaki M; Hepatobiliary and Pancreatic Surgery.
Morizane C; Hepatobiliary and Pancreatic Oncology.; Rare Cancer Center, National Cancer Center Hospital.
Okuma T; Orthopedic Surgery and Musculoskeletal Oncology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Kawai A; Musculoskeletal Oncology.; Rare Cancer Center, National Cancer Center Hospital.
Ushiku T; Department of Pathology, the University of Tokyo Hospital.
Yatabe Y; Departments of Diagnostic Pathology.
Yoshida A; Departments of Diagnostic Pathology.; Rare Cancer Center, National Cancer Center Hospital.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 May 01; Vol. 45 (5), pp. 616-626.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*analysis
Hemangioendothelioma, Epithelioid/*chemistry
Synaptophysin/*analysis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Female ; Hemangioendothelioma, Epithelioid/genetics ; Hemangioendothelioma, Epithelioid/mortality ; Hemangioendothelioma, Epithelioid/pathology ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Mitosis ; Necrosis ; Neoplasm Grading ; Predictive Value of Tests ; RNA-Seq ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Young Adult
Czasopismo naukowe
Tytuł :
[Effects of different intensity exercise on morphology and structure of atrioventricular node and protein expressions of VEGF, VIP and Syn in rats].
Autorzy :
Wang YH; Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an 710119, China.
Chen W; Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an 710119, China.
Ma M; Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an 710119, China.
Dai GY; Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an 710119, China.
Hua YJ; Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an 710119, China.
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Źródło :
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology [Zhongguo Ying Yong Sheng Li Xue Za Zhi] 2021 May; Vol. 37 (3), pp. 287-292.
Typ publikacji :
Journal Article
MeSH Terms :
Physical Conditioning, Animal*
Vasoactive Intestinal Peptide*
Animals ; Atrioventricular Node ; Endothelial Cells ; Rats ; Rats, Sprague-Dawley ; Synaptophysin ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Tytuł :
Accumulation of PSA-NCAM marks nascent neurodegeneration in the dorsal hippocampus after neonatal hypoxic-ischemic brain injury in mice.
Autorzy :
Chavez-Valdez R; Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lechner C; Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Emerson P; Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA.
Northington FJ; Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Martin LJ; Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
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Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2021 May; Vol. 41 (5), pp. 1039-1057. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Injuries/*metabolism
Hippocampus/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Neural Cell Adhesion Molecule L1/*metabolism
Neurodegenerative Diseases/*metabolism
Sialic Acids/*metabolism
Animals ; Brain Injuries/pathology ; CA1 Region, Hippocampal/metabolism ; Female ; GABAergic Neurons/cytology ; GABAergic Neurons/metabolism ; GABAergic Neurons/pathology ; Glutamate Decarboxylase/metabolism ; Hypoxia-Ischemia, Brain/complications ; Injury Severity Score ; Male ; Memory Disorders/metabolism ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Neural Cell Adhesion Molecule L1/immunology ; Neurodegenerative Diseases/etiology ; Neurodegenerative Diseases/pathology ; Sialic Acids/immunology ; Synaptophysin/metabolism ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
Autorzy :
Akinyemi AR; Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, 230001, China; Neurodegenerative Disease Research Center, University of Science and Technology of China, Hefei, 230026, China; CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, 230026, China.
Li D; Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, 230001, China; Neurodegenerative Disease Research Center, University of Science and Technology of China, Hefei, 230026, China; CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, 230026, China; National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, 230029, China.
Zhang J; Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, 230001, China; Neurodegenerative Disease Research Center, University of Science and Technology of China, Hefei, 230026, China; CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, 230026, China. Electronic address: .
Liu Q; Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, 230001, China; Neurodegenerative Disease Research Center, University of Science and Technology of China, Hefei, 230026, China; CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, 230026, China; CAS Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, 650223, China. Electronic address: .
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Źródło :
Neuroscience letters [Neurosci Lett] 2021 Apr 23; Vol. 751, pp. 135824. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuronal Plasticity*
Cognitive Dysfunction/*metabolism
Heterogeneous-Nuclear Ribonucleoprotein Group M/*metabolism
Animals ; CA1 Region, Hippocampal/growth & development ; CA1 Region, Hippocampal/metabolism ; Cell Line, Tumor ; Cells, Cultured ; Cognitive Dysfunction/genetics ; Dendritic Spines/metabolism ; Disks Large Homolog 4 Protein/genetics ; Disks Large Homolog 4 Protein/metabolism ; HEK293 Cells ; Heterogeneous-Nuclear Ribonucleoprotein Group M/deficiency ; Heterogeneous-Nuclear Ribonucleoprotein Group M/genetics ; Humans ; Mice ; Mice, Inbred C57BL ; RNA Stability ; Synaptophysin/genetics ; Synaptophysin/metabolism
Czasopismo naukowe

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