Temat: "system pharmacology" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Development of a chemogenomics library for phenotypic screening.
Autorzy:: Dafniet B; Université de Paris, INSERM U1133, CNRS UMR8251, 75006, Paris, France.
Cerisier N; Université de Paris, INSERM U1133, CNRS UMR8251, 75006, Paris, France.
Boezio B; Université de Paris, INSERM U1133, CNRS UMR8251, 75006, Paris, France.
Clary A; Institut de Recherche Servier, 125 Chemin de Ronde, 78290, Croissy-sur-Seine, France.
Ducrot P; Institut de Recherche Servier, 125 Chemin de Ronde, 78290, Croissy-sur-Seine, France.
Dorval T; Institut de Recherche Servier, 125 Chemin de Ronde, 78290, Croissy-sur-Seine, France.
Gohier A; Institut de Recherche Servier, 125 Chemin de Ronde, 78290, Croissy-sur-Seine, France.
Brown D; Institut de Recherche Servier, 125 Chemin de Ronde, 78290, Croissy-sur-Seine, France.
Audouze K; Université de Paris, INSERM UMR S-1124, 75006, Paris, France.
Taboureau O; Université de Paris, INSERM U1133, CNRS UMR8251, 75006, Paris, France. .; Pokaż więcej
Źródło:: Journal of cheminformatics [J Cheminform] 2021 Nov 24; Vol. 13 (1), pp. 91. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji:: Journal Article

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Skocz do pozycji: 2.

Tytuł:: Bacopa monnieri and Their Bioactive Compounds Inferred Multi-Target Treatment Strategy for Neurological Diseases: A Cheminformatics and System Pharmacology Approach.
Autorzy:: Jeyasri R; Department of Biotechnology, Science Campus, Alagappa University, Karaikudi 630 003, India.
Muthuramalingam P; Department of Biotechnology, Science Campus, Alagappa University, Karaikudi 630 003, India.
Suba V; Department of Biotechnology, Science Campus, Alagappa University, Karaikudi 630 003, India.
Ramesh M; Department of Biotechnology, Science Campus, Alagappa University, Karaikudi 630 003, India.
Chen JT; Department of Life Sciences, National University of Kaohsiung, Kaohsiung 811, Taiwan.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 Apr 02; Vol. 10 (4). Date of Electronic Publication: 2020 Apr 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cheminformatics*
Molecular Targeted Therapy*
Systems Biology*
Bacopa/*chemistry
Nervous System Diseases/*drug therapy
Plant Extracts/*pharmacology
Gene Ontology ; Humans ; Nervous System Diseases/genetics ; Plant Extracts/therapeutic use

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Skocz do pozycji: 3.

Tytuł:: A network pharmacology approach to explore the mechanisms of Erxian decoction in polycystic ovary syndrome.
Autorzy:: Liu L; 1Department of Gynecological Ward, The Third Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.
Du B; 1Department of Gynecological Ward, The Third Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.
Zhang H; 3Library Department, Jinzhou Medical University, Jinzhou, China.
Guo X; 1Department of Gynecological Ward, The Third Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.
Zhou Z; 1Department of Gynecological Ward, The Third Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.
Xiu A; 4Department of Gynecological Ward, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.
Liu C; 1Department of Gynecological Ward, The Third Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.
Su S; 1Department of Gynecological Ward, The Third Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.
Ai H; Liaoning Provincial Key Laboratory of Follicle Development and Reproductive Health (Office of Science and Technology), Jinzhou, China.; 4Department of Gynecological Ward, The First Affiliated Hospital, Jinzhou Medical University, Jinzhou, China.; Pokaż więcej
Źródło:: Chinese medicine [Chin Med] 2018 Aug 29; Vol. 13, pp. 46. Date of Electronic Publication: 2018 Aug 29 (Print Publication: 2018).
Typ publikacji:: Journal Article

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Skocz do pozycji: 4.

Tytuł:: Network Medicine for Alzheimer's Disease and Traditional Chinese Medicine.
Autorzy:: Jarrell JT; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA. .
Gao L; Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China. .
Cohen DS; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA. .
Huang X; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 May 11; Vol. 23 (5). Date of Electronic Publication: 2018 May 11.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Medicine, Chinese Traditional*
Alzheimer Disease/*drug therapy
Drugs, Chinese Herbal/*therapeutic use
Alzheimer Disease/diagnosis ; Alzheimer Disease/etiology ; Alzheimer Disease/metabolism ; Biomarkers ; Drugs, Chinese Herbal/pharmacology ; Gene Expression Regulation ; Humans ; Myelin Sheath/metabolism ; Myeloid Cells/metabolism ; Signal Transduction

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Skocz do pozycji: 5.

Tytuł:: Integration of transcriptomics, proteomics, metabolomics and systems pharmacology data to reveal the therapeutic mechanism underlying Chinese herbal Bufei Yishen formula for the treatment of chronic obstructive pulmonary disease.
Autorzy:: Zhao P; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, P.R. China.
Li J; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, P.R. China.
Yang L; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, P.R. China.
Li Y; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, P.R. China.
Tian Y; Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, P.R. China.
Li S; Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment and Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Apr; Vol. 17 (4), pp. 5247-5257. Date of Electronic Publication: 2018 Jan 25.
Typ publikacji:: Journal Article
MeSH Terms:: Metabolome*
Proteome*
Transcriptome*
Drugs, Chinese Herbal/*pharmacology
Pulmonary Disease, Chronic Obstructive/*genetics
Pulmonary Disease, Chronic Obstructive/*metabolism
Animals ; Computational Biology ; Disease Models, Animal ; Gene Expression Profiling/methods ; Gene Regulatory Networks ; Metabolic Networks and Pathways ; Metabolomics/methods ; Oxidative Stress ; Pharmacology, Clinical/methods ; Proteomics/methods ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Rats ; Signal Transduction ; Systems Biology/methods

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