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Title:
Identification, characterization and spatiotemporal expression analysis of the FKBP family genes in Locusta migratoria.
Authors:
Zhang N; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.; Scientific Observation and Experimental Station of Pests in Xilingol Rangeland, Ministry of Agriculture and Rural Affairs, Xilinhot, 026000, China.
Feng S; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Tian Y; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Zhuang L; Bayannur Forestry and Grassland Development Center, Bayannur, 015000, China.
Cha G; Bayannur Forestry and Grassland Development Center, Bayannur, 015000, China.
Duan S; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Li H; MARA-CABI Joint Laboratory for Bio-Safety, Institute of Plant Protection, Chinese Academy of Agricultural Science, Beijing, 100193, China.
Nong X; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Zhang Z; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Tu X; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.; Scientific Observation and Experimental Station of Pests in Xilingol Rangeland, Ministry of Agriculture and Rural Affairs, Xilinhot, 026000, China.
Wang G; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. .; Scientific Observation and Experimental Station of Pests in Xilingol Rangeland, Ministry of Agriculture and Rural Affairs, Xilinhot, 026000, China. .
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Source:
Scientific reports [Sci Rep] 2023 Mar 10; Vol. 13 (1), pp. 4048. Date of Electronic Publication: 2023 Mar 10.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tacrolimus Binding Proteins*/genetics
Locusta migratoria*/genetics
Male ; Animals ; Female ; Phylogeny ; Protein Folding ; Tacrolimus
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells.
Authors:
Quist-Løkken I; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.
Andersson-Rusch C; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.
Kastnes MH; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.
Kolos JM; Department of Chemistry, Technical University of Darmstadt, Darmstadt, Germany.
Jatzlau J; Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Hella H; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.
Olsen OE; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.
Sundan A; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.; Department of Hematology, St. Olav's University Hospital, Trondheim, Norway.
Knaus P; Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Hausch F; Department of Chemistry, Technical University of Darmstadt, Darmstadt, Germany.
Holien T; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway. .; Department of Immunology and Transfusion Medicine, St. Olav's University Hospital, Trondheim, Norway. .; Department of Hematology, St. Olav's University Hospital, Trondheim, Norway. .; Department of Biomedical Laboratory Science, Norwegian University of Science and Technology - NTNU, Trondheim, Norway. .
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Source:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Jan 30; Vol. 21 (1), pp. 25. Date of Electronic Publication: 2023 Jan 30.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:
Multiple Myeloma*
Tacrolimus Binding Protein 1A*/metabolism
Activin Receptors, Type I*/metabolism
Humans ; Bone Morphogenetic Proteins/metabolism ; RNA, Small Interfering ; Tacrolimus/pharmacology
Academic Journal
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Title:
A case report of drug interaction between co-packaged nirmatrelvir-ritonavir and tacrolimus causing hyponatremia in a lung transplant recipient.
Authors:
Lo CM; Division of Thoracic and Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC. .
Chen WH; Division of Thoracic and Cardiovascular Surgery, Linko Chang Gung Memorial Hospital, Linkou, Taiwan, ROC.
Tsai MY; Division of Chest, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Lu HI; Division of Thoracic and Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Hsiao YH; Division of Thoracic and Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Chuang KH; Division of Thoracic and Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Chen Y; Division of Thoracic and Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Wu HF; Division of Chest, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Huang KT; Division of Chest, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
Wang YH; Division of Chest, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
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Source:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Mar 15; Vol. 19 (1), pp. 132. Date of Electronic Publication: 2024 Mar 15.
Publication Type:
Case Reports; Journal Article
MeSH Terms:
Hyponatremia*/chemically induced
Lactams*/adverse effects
Leucine*/adverse effects
Nitriles*/adverse effects
Proline*/adverse effects
Tacrolimus*/adverse effects
Female ; Humans ; Middle Aged ; Drug Interactions ; Lung ; Ritonavir/adverse effects ; Transplant Recipients
Academic Journal
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Title:
Bacterial Chaperone Domain Insertions Convert Human FKBP12 into an Excellent Protein-Folding Catalyst-A Structural and Functional Analysis.
Authors:
Žoldák G; Center for Interdisciplinary Biosciences, Technology and Innovation Park, Pavol Jozef Šafárik University in Košice, 040 11 Kosice, Slovakia.
Knappe TA; Laboratorium für Biochemie und Bayreuther Zentrum für Molekulare Biowissenschaften, Universität Bayreuth, 95447 Bayreuth, Germany.
Geitner AJ; Laboratorium für Biochemie und Bayreuther Zentrum für Molekulare Biowissenschaften, Universität Bayreuth, 95447 Bayreuth, Germany.
Scholz C; Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany.
Dobbek H; Institut für Biologie, Strukturbiologie/Biochemie, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099 Berlin, Germany.
Schmid FX; Laboratorium für Biochemie und Bayreuther Zentrum für Molekulare Biowissenschaften, Universität Bayreuth, 95447 Bayreuth, Germany.
Jakob RP; Departement Biozentrum, University of Basel, Spitalstrasse 41, 4056 Basel, Switzerland.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 23; Vol. 29 (7). Date of Electronic Publication: 2024 Mar 23.
Publication Type:
Journal Article
MeSH Terms:
Tacrolimus Binding Protein 1A*
Escherichia coli Proteins*
Humans ; Escherichia coli/genetics ; Molecular Chaperones ; Peptidylprolyl Isomerase/genetics ; Catalysis
Academic Journal
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Title:
Novel immunosuppressive effect of FK506 by upregulation of PD-L1 via FKBP51 in heart transplantation.
Authors:
Luo X; Medical College of Guangxi University, Nanning, China.; Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Xiamen, China.
Du G; Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Xiamen, China.
Chen B; Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Xiamen, China.
Yan G; School of Medicine, Xiamen University, Xiamen, China.
Zhu L; Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Xiamen, China.
Cui P; Medical College of Guangxi University, Nanning, China.; Clinical Research Center for Organ Transplantation in Hunan Province, Changsha, China.
Dai H; Clinical Research Center for Organ Transplantation in Hunan Province, Changsha, China.; Department of Kidney Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China.; Clinical Immunology Center, Central South University, Changsha, China.
Qi Z; Medical College of Guangxi University, Nanning, China.; Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Xiamen, China.
Lan T; Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Xiamen, China.; Institute of Respiratory Diseases，Xiamen Medical College, Xiamen, China.
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Source:
Scandinavian journal of immunology [Scand J Immunol] 2022 Oct; Vol. 96 (4), pp. e13203. Date of Electronic Publication: 2022 Jul 18.
Publication Type:
Journal Article
MeSH Terms:
Heart Transplantation*
Tacrolimus*/pharmacology
Animals ; B7-H1 Antigen/metabolism ; Mice ; Programmed Cell Death 1 Receptor/metabolism ; Tacrolimus Binding Proteins/metabolism ; Up-Regulation
Academic Journal
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Title:
Tacrolimus versus mycophenolate for AutoImmune hepatitis patients with incompLete response On first-line therapy (TAILOR study): a study protocol for a phase III, open-label, multicentre, randomised controlled trial.
Authors:
Stoelinga AEC; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands. .
Tushuizen ME; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
van den Hout WB; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
Girondo MDMR; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
de Vries ES; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gastroenterology and Hepatology, Isala Hospital, Zwolle, The Netherlands.
Levens AD; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Moes DAR; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Gevers TJG; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.; European Reference Network RARE-LIVER, Hamburg, Germany.
van der Meer S; Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.
Brouwer HT; Department of Gastroenterology and Hepatology, Reinier de Graaf Gasthuis, Delft, The Netherlands.
de Jonge HJM; Department of Gastroenterology and Hepatology, Jeroen Bosch Hospital, 'S-Hertogenbosch, The Netherlands.
de Boer YS; European Reference Network RARE-LIVER, Hamburg, Germany.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centre, Location VU University Medical Center, Amsterdam, The Netherlands.
Beuers UHW; European Reference Network RARE-LIVER, Hamburg, Germany.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centre, Location Academic Medical Center, Amsterdam, The Netherlands.
van der Meer AJ; European Reference Network RARE-LIVER, Hamburg, Germany.; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
van den Berg AP; European Reference Network RARE-LIVER, Hamburg, Germany.; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
Guichelaar MMJ; Department of Gastroenterology and Hepatology, Medisch Spectrum Twente, Enschede, The Netherlands.
Drenth JPH; European Reference Network RARE-LIVER, Hamburg, Germany.; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.
van Hoek B; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
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Corporate Authors:
Dutch Autoimmune Hepatitis Group
Source:
Trials [Trials] 2024 Jan 17; Vol. 25 (1), pp. 61. Date of Electronic Publication: 2024 Jan 17.
Publication Type:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Tacrolimus*/adverse effects
Hepatitis, Autoimmune*/diagnosis
Hepatitis, Autoimmune*/drug therapy
Humans ; Quality of Life ; Retrospective Studies ; Treatment Outcome ; Immunosuppressive Agents/adverse effects ; Mycophenolic Acid/adverse effects ; Enzyme Inhibitors/therapeutic use ; Liver Cirrhosis/drug therapy ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic ; Clinical Trials, Phase III as Topic
Academic Journal
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Title:
Nerve Wrap for Local Delivery of FK506/Tacrolimus Accelerates Nerve Regeneration.
Authors:
Xiao B; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.
Feturi F; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.
Su AA; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.; Department of Surgery, Division of Plastic Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Van der Merwe Y; Department of Ophthalmology, University of California, San Diego, CA 90095, USA.
Barnett JM; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.
Jabbari K; Department of Surgery, Division of Plastic Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Khatter NJ; Department of Surgery, Division of Plastic Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Li B; Department of Surgery, Division of Plastic Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Katzel EB; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.
Venkataramanan R; University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15213, USA.
Solari MG; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.
Wagner WR; McGowan Institute for Regenerative Medicine, Pittsburgh, PA 15219, USA.
Steketee MB; Department of Ophthalmology, University of California, San Diego, CA 90095, USA.; McGowan Institute for Regenerative Medicine, Pittsburgh, PA 15219, USA.
Simons DJ; McGowan Institute for Regenerative Medicine, Pittsburgh, PA 15219, USA.
Washington KM; Department of Plastic Surgery, University of Pittsburgh School of Medicine, Veterans Administration Healthcare System, Pittsburgh, PA 15213, USA.; Department of Surgery, Division of Plastic Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; McGowan Institute for Regenerative Medicine, Pittsburgh, PA 15219, USA.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 10; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 10.
Publication Type:
Journal Article
MeSH Terms:
Tacrolimus*/pharmacology
Myelin Sheath*
Animals ; Rats ; Neurons ; Urethane ; Nerve Regeneration ; Amides ; Carbamates ; Urea ; Esters
Academic Journal
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Title:
Safety and efficacy of Pimecrolimus in atopic dermatitis among Chinese infants: a sub-group analysis of a five-year open-label study.
Authors:
Dou X; Department of Dermatology, Peking University First Hospital, Beijing, China.
Liu L; Department of Dermatology, Peking University First Hospital, Beijing, China.
Zhu X; Department of Dermatology, Peking University First Hospital, Beijing, China.
Wen W; Department of Dermatology, Peking University First Hospital, Beijing, China.
Ni C; Department of Dermatology, Peking University First Hospital, Beijing, China.
Zhao Y; Department of Dermatology, Peking University First Hospital, Beijing, China.
He Z; Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
Li H; Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
Sun Q; Department of Dermatology, Peking Union Medical College Hospital, Beijing, China.
Yang Q; Department of Dermatology, Shanghai Huashan Hospital, Shanghai, China.
Sun X; Department of Dermatology, Shanghai Huashan Hospital, Shanghai, China.
Guo Y; Department of Dermatology, Shanghai XinHua Hospital, Shanghai, China.
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Source:
The Journal of dermatological treatment [J Dermatolog Treat] 2023 Dec; Vol. 34 (1), pp. 2229464.
Publication Type:
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Dermatitis, Atopic*/drug therapy
Dermatologic Agents*/administration & dosage
Dermatologic Agents*/adverse effects
Dermatologic Agents*/therapeutic use
Tacrolimus*/administration & dosage
Tacrolimus*/adverse effects
Tacrolimus*/analogs & derivatives
Tacrolimus*/therapeutic use
Humans ; Infant ; East Asian People ; Treatment Outcome ; Administration, Topical ; Glucocorticoids/administration & dosage ; Glucocorticoids/adverse effects ; Glucocorticoids/therapeutic use ; Skin Cream
Academic Journal
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Title:
Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.
Authors:
Großmann NL; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475 Greifswald, Germany.
Weihs A; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475 Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, 17489 Greifswald, Germany.
Kühn L; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475 Greifswald, Germany.
Sauer S; Department Genes and Environment, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Röh S; Department Genes and Environment, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Wiechmann T; Department Genes and Environment, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Rex-Haffner M; Department Genes and Environment, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Völzke H; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, University Medicine Greifswald, 17475 Greifswald, Germany.
Völker U; German Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, University Medicine Greifswald, 17475 Greifswald, Germany.; Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany.
Binder EB; Department Genes and Environment, Max Planck Institute of Psychiatry, 80804 Munich, Germany.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
Teumer A; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475 Greifswald, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, University Medicine Greifswald, 17475 Greifswald, Germany.
Homuth G; Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany.
Klinger-König J; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475 Greifswald, Germany.
Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475 Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, 17489 Greifswald, Germany.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 25; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 25.
Publication Type:
Journal Article
MeSH Terms:
Child Abuse*
Depressive Disorder*/genetics
DNA Methylation*
Tacrolimus Binding Proteins*/genetics
Adult ; Child ; Humans ; Hydrocortisone ; Hypothalamo-Hypophyseal System/metabolism ; Introns/genetics ; Pituitary-Adrenal System/metabolism ; Polymorphism, Single Nucleotide
Academic Journal
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Title:
Secretome Analyses Identify FKBP4 as a GBA1 -Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations.
Authors:
Kojima R; Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.
Paslawski W; Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.
Lyu G; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Arenas E; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
Zhang X; Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.
Svenningsson P; Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 04; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 04.
Publication Type:
Journal Article
MeSH Terms:
Induced Pluripotent Stem Cells*
Parkinson Disease*/genetics
Tacrolimus Binding Proteins*/genetics
Humans ; Cerebrospinal Fluid Proteins ; Membrane Proteins ; Mutation ; Nerve Tissue Proteins ; Protein Disulfide-Isomerases ; Secretome
Academic Journal
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Title:
Rapid intestinal and systemic metabolic reprogramming in an immunosuppressed environment.
Authors:
Ma B; Institute of Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .
Gavzy SJ; Department of Surgery, University of Maryland Medical Center, Baltimore, MD, 21201, USA.; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
France M; Institute of Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Song Y; Institute of Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Lwin HW; Institute of Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Kensiski A; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Saxena V; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Piao W; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Lakhan R; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Iyyathurai J; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Li L; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Paluskievicz C; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Wu L; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
WillsonShirkey M; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Mongodin EF; Institute of Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Division of Lung Diseases, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.
Mas VR; Department of Surgery, University of Maryland Medical Center, Baltimore, MD, 21201, USA.
Bromberg JS; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .; Department of Surgery, University of Maryland Medical Center, Baltimore, MD, 21201, USA. .; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .
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Source:
BMC microbiology [BMC Microbiol] 2023 Dec 09; Vol. 23 (1), pp. 394. Date of Electronic Publication: 2023 Dec 09.
Publication Type:
Journal Article
MeSH Terms:
Tacrolimus*
Animals ; Mice ; Immunosuppressive Agents/pharmacology ; Metabolome ; Metabolomics
Academic Journal
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Title:
Tremor Induced by Cyclosporine, Tacrolimus, Sirolimus, or Everolimus: A Review of the Literature.
Authors:
Wagle Shukla A; Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Fixel Institute for Neurological Disorders, 3009 Williston Road, Gainesville, FL, 32608, USA. .
Lunny C; Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Fixel Institute for Neurological Disorders, 3009 Williston Road, Gainesville, FL, 32608, USA.
Mahboob O; Florida State University Medical School, Tallahassee, FL, USA.
Khalid U; University of Toronto Medical School, Toronto, ON, Canada.
Joyce M; North Florida South Georgia Veteran Healthcare System, Gainesville, FL, USA.
Jha N; Department of Neurology, Tower Health, Reading Hospital, Reading, PA, USA.
Nagaraja N; Department of Neurology, Penn State University College of Medicine, Milton S. Hershey Medical Center, Hershey, PA, USA.
Shukla AM; North Florida South Georgia Veteran Healthcare System, Gainesville, FL, USA.; Division of Nephrology, Department of Medicine, University of Florida, Gainesville, FL, USA.
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Source:
Drugs in R&D [Drugs R D] 2023 Dec; Vol. 23 (4), pp. 301-329. Date of Electronic Publication: 2023 Aug 22.
Publication Type:
Journal Article; Review
MeSH Terms:
Cyclosporine*/adverse effects
Tacrolimus*/adverse effects
Humans ; Everolimus/adverse effects ; Sirolimus/therapeutic use ; Tremor/chemically induced ; Tremor/epidemiology ; Tremor/drug therapy ; Prospective Studies ; Retrospective Studies ; Immunosuppressive Agents ; Calcineurin Inhibitors/adverse effects
Academic Journal
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Title:
Effect of FKBP12-Derived Intracellular Peptides on Rapamycin-Induced FKBP-FRB Interaction and Autophagy.
Authors:
Parada CA; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
de Oliveira IP; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.; Institute of Agricultural Sciences, Federal University of Minas Gerais, Montes Claros 39400-149, MG, Brazil.
Gewehr MCF; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Machado-Neto JA; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Lima K; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Eichler RAS; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Lopes LR; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Bechara LRG; Departments of Anatomy, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Ferreira JCB; Departments of Anatomy, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Festuccia WT; Departments of Physiology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Censoni L; Department of Physical Chemistry, Institute of Chemistry, University of Campinas, Campinas 13083-970, SP, Brazil.
Tersariol ILS; Department of Biochemistry, Paulista Medical School, São Paulo Federal University (UNIFESP), São Paulo 04021-001, SP, Brazil.
Ferro ES; Departments of Pharmacology, Biomedical Sciences Institute, University of São Paulo, São Paulo 05508-900, SP, Brazil.
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Source:
Cells [Cells] 2022 Jan 24; Vol. 11 (3). Date of Electronic Publication: 2022 Jan 24.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sirolimus*/pharmacology
Tacrolimus Binding Protein 1A*/metabolism
Animals ; Autophagy ; Fibroblasts/metabolism ; HEK293 Cells ; Humans ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Peptides/pharmacology ; Tacrolimus ; Tacrolimus Binding Proteins/metabolism
Academic Journal
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Title:
Advancing Nerve Regeneration: Translational Perspectives of Tacrolimus (FK506).
Authors:
Daeschler SC; Department of Hand, Plastic and Reconstructive Surgery, Burn Center, Department of Plastic and Hand Surgery, University of Heidelberg, BG Trauma Hospital, D-67071 Ludwigshafen, Germany.; Neuroscience and Mental Health Program, SickKids Research Institute, Toronto, ON M5G 1X8, Canada.
Feinberg K; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Harhaus L; Department of Hand, Plastic and Reconstructive Surgery, Burn Center, Department of Plastic and Hand Surgery, University of Heidelberg, BG Trauma Hospital, D-67071 Ludwigshafen, Germany.
Kneser U; Department of Hand, Plastic and Reconstructive Surgery, Burn Center, Department of Plastic and Hand Surgery, University of Heidelberg, BG Trauma Hospital, D-67071 Ludwigshafen, Germany.
Gordon T; Department of Surgery, University of Toronto, Toronto, ON M5G 2C4, Canada.; Division of Plastic and Reconstructive Surgery, The Hospital for Sick Children, Toronto, ON M5G 2C4, Canada.
Borschel GH; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
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International journal of molecular sciences [Int J Mol Sci] 2023 Aug 14; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 14.
Publication Type:
Journal Article; Review
MeSH Terms:
Tacrolimus*/pharmacology
Tacrolimus*/therapeutic use
Medicine*
Humans ; Immunosuppressive Agents/pharmacology ; Immunosuppressive Agents/therapeutic use ; Administration, Cutaneous ; Nerve Regeneration
Academic Journal
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Title:
Local Net Charge State of Collagen Triple Helix Is a Determinant of FKBP22 Binding to Collagen III.
Authors:
Ishikawa Y; Department of Ophthalmology, University of California San Francisco, School of Medicine, San Francisco, CA 941583, USA.
Bonna A; Department of Biochemistry, Downing Site, Cambridge CB2 1QW, UK.
Gould DB; Department of Ophthalmology, University of California San Francisco, School of Medicine, San Francisco, CA 941583, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA.; Cardiovascular Research Institute, University of California, San Francisco, CA 94158, USA.; Bakar Aging Research Institute, University of California, San Francisco, CA 94143, USA.; Institute for Human Genetics, University of California, San Francisco, CA 94143, USA.
Farndale RW; Department of Biochemistry, Downing Site, Cambridge CB2 1QW, UK.
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International journal of molecular sciences [Int J Mol Sci] 2023 Oct 13; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 13.
Publication Type:
Journal Article
MeSH Terms:
Tacrolimus Binding Proteins*/metabolism
Ehlers-Danlos Syndrome*/genetics
Humans ; Collagen/genetics ; Peptidylprolyl Isomerase/genetics ; Mutation
Academic Journal
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Title:
Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients.
Authors:
Alghamdi A; Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Seay S; Department of Chemistry, Virginia Tech Center for Drug Discovery, Blacksburg, Virginia, USA.
Hooper DK; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Nephrology & Hypertension, James M. Anderson Center fo Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Varnell CD Jr; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Nephrology & Hypertension, James M. Anderson Center fo Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Darland L; Division of Pharmacy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Mizuno T; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Lazear D; Division of Pharmacy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Ramsey LB; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Divisions of Clinical Pharmacology & Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
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Source:
Clinical and translational science [Clin Transl Sci] 2023 Oct; Vol. 16 (10), pp. 1768-1778. Date of Electronic Publication: 2023 Jun 26.
Publication Type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Tacrolimus*
Kidney Transplantation*/adverse effects
Humans ; Child ; Cytochrome P-450 CYP3A/genetics ; Fluconazole ; Immunosuppressive Agents ; Genotype ; Dose-Response Relationship, Drug ; Polymorphism, Single Nucleotide
Academic Journal
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Title:
A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain.
Authors:
Maiarù M; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.; Department of Pharmacology, School of Pharmacy, University of Reading, Reading, UK.
Acton RJ; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.; Human Development and Health, Institute of Developmental Sciences, University of Southampton, Southampton, UK.; William Harvey Research Institute, Barts & The London Faculty of Medicine, Charterhouse Square, Queen Mary University of London, London, EC1M 6BQ, UK.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Woźniak EL; Genome Centre, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK.
Mein CA; Genome Centre, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK.
Bell CG; William Harvey Research Institute, Barts & The London Faculty of Medicine, Charterhouse Square, Queen Mary University of London, London, EC1M 6BQ, UK.
Géranton SM; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK. .
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Clinical epigenetics [Clin Epigenetics] 2023 Sep 30; Vol. 15 (1), pp. 155. Date of Electronic Publication: 2023 Sep 30.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chronic Pain*/genetics
DNA Methylation*
Tacrolimus Binding Proteins*/genetics
Humans ; Epigenesis, Genetic ; Gene Expression Regulation ; Maternal Deprivation
Academic Journal
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Title:
Comparison of oral itraconazole given for two days plus topical tacrolimus versus topical tacrolimus for maintenance treatment of seborrheic dermatitis in Vietnam.
Authors:
Thi Thu Do H; Department of General Planning, Hanoi, Vietnam.
Van Le T; Department of Dermatology, Kagoshima University Graduate School of Medical and Dental, Kagoshima, Japan.
Kanekura T; Department of Dermatology, Kagoshima University Graduate School of Medical and Dental, Kagoshima, Japan.
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Source:
Indian journal of dermatology, venereology and leprology [Indian J Dermatol Venereol Leprol] 2023 Sep-Oct; Vol. 89 (5), pp. 748-750.
Publication Type:
Letter
MeSH Terms:
Tacrolimus*/therapeutic use
Dermatitis, Seborrheic*/diagnosis
Dermatitis, Seborrheic*/drug therapy
Humans ; Itraconazole ; Vietnam ; Antifungal Agents ; Immunosuppressive Agents ; Administration, Topical ; Treatment Outcome
Editorial & Opinion
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Title:
Analytical and Clinical Validation of Assays for Volumetric Absorptive Microsampling (VAMS) of Drugs in Different Blood Matrices: A Literature Review.
Authors:
Nugraha RV; Doctoral Study Program, Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.
Yunivita V; Division of Pharmacology and Therapy, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.
Santoso P; Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran-Hasan Sadikin Hospital, Bandung 40161, Indonesia.
Hasanah AN; Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia.
Aarnoutse RE; Department of Pharmacy, Radboud University Medical Center, Research Institute for Medical Innovation, 6255 HB Nijmegen, The Netherlands.
Ruslami R; Division of Pharmacology and Therapy, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 14; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 14.
Publication Type:
Journal Article; Review
MeSH Terms:
Mycophenolic Acid*
Tacrolimus*
Biological Assay
Academic Journal
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Title:
Graft-recipient-weight ratio and lowered immunosuppression is important for the success of adult liver retransplantation.
Authors:
Rhu J; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
Kwon J; Department of Surgery, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
Lim M; Department of Surgery, Myungji Hospital, Hanyang University Medical Center, Goyang, Korea.
Oh N; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
An S; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
Han SW; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
Jo SJ; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
Park S; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
Choi GS; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
Kim JM; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea. .
Joh JW; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-Dong, Gangnam-Gu, Seoul, 135-710, Korea.
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Source:
Scientific reports [Sci Rep] 2023 Aug 07; Vol. 13 (1), pp. 12778. Date of Electronic Publication: 2023 Aug 07.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tacrolimus*/therapeutic use
Liver Transplantation*/adverse effects
Humans ; Adult ; Reoperation ; Liver ; Immunosuppression Therapy ; Graft Survival ; Retrospective Studies
Academic Journal
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Showing 1-20 from 29681 results

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