Temat: "tat" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: HIV-1 Tat Induces Dysregulation of PGC1-Alpha and Sirtuin 3 Expression in Neurons: The Role of Mitochondrial Biogenesis in HIV-Associated Neurocognitive Disorder (HAND).
Autorzy:: Figarola-Centurión I; Doctorado en Genética Humana, Departamento de Biología Molecular y Genómica, Universidad de Guadalajara, Guadalajara 44340, Mexico.; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.
Escoto-Delgadillo M; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Guadalajara 44600, Mexico.
González-Enríquez GV; Departamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Gutiérrez-Sevilla JE; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Doctorado en Microbiología Médica, Departamento de Microbiología y Patología, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Vázquez-Valls E; Investigación y Calidad de Salud, Secretaría de Salud, Guadalajara 44100, Mexico.
Cárdenas-Bedoya J; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Departamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Torres-Mendoza BM; Laboratorio de Inmunodeficiencias y Retrovirus Humanos, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.; Departamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 17; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: HIV Infections*/metabolism
HIV-1*/metabolism
Neurocognitive Disorders*/metabolism
Neurocognitive Disorders*/virology
Sirtuin 3*/genetics
Sirtuin 3*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Animals ; Rats ; Gene Products, tat/metabolism ; Neurons/metabolism ; Organelle Biogenesis ; Protein Kinases/metabolism ; Rats, Sprague-Dawley ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

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Skocz do pozycji: 2.

Tytuł:: TAT peptide at treatment-level concentrations crossed brain endothelial cell monolayer independent of receptor-mediated endocytosis or peptide-inflicted barrier disruption.
Autorzy:: Wu MC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Wang EY; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.
Lai TW; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.; Neuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.; Drug Development Center, China Medical University, Taichung, Taiwan.; Translational Medicine Research Center, China Medical University Hospital, Taichung, Taiwan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Oct 11; Vol. 18 (10), pp. e0292681. Date of Electronic Publication: 2023 Oct 11 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Endothelial Cells*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Brain/metabolism ; Blood-Brain Barrier/metabolism ; Peptides/metabolism ; Endocytosis

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Skocz do pozycji: 3.

Tytuł:: HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter.
Autorzy:: Anastasopoulou S; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Georgakopoulos T; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Mouzaki A; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 May 24; Vol. 13 (6). Date of Electronic Publication: 2023 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: HIV Infections*/genetics
HIV Infections*/immunology
HIV Infections*/virology
HIV-1*/genetics
HIV-1*/metabolism
Interleukin-2*/genetics
Interleukin-2*/metabolism
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Humans ; Gene Expression Regulation, Viral ; Transcription Factors/metabolism ; Transcription, Genetic ; Transcriptional Activation

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Skocz do pozycji: 4.

Tytuł:: A Novel Time-Resolved Fluorescence Resonance Energy Transfer Assay for the Discovery of Small-Molecule Inhibitors of HIV-1 Tat-Regulated Transcription.
Autorzy:: Shin YH; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Kim DE; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Yu KL; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Park CM; Department for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Daejeon 34114, Republic of Korea.
Kim HG; Department for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Daejeon 34114, Republic of Korea.
Kim KC; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Bae S; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.
Yoon CH; Division of Chronic Viral Diseases, Center for Emerging Virus Research, Korea National Institute of Health, 187 Osongsaengmyeong 2-ro, Cheongju 363951, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 23; Vol. 24 (11). Date of Electronic Publication: 2023 May 23.
Typ publikacji:: Journal Article
MeSH Terms:: tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/chemistry
HIV-1*/physiology
Humans ; Fluorescence Resonance Energy Transfer ; Trans-Activators ; RNA, Viral/genetics

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Skocz do pozycji: 5.

Tytuł:: Bioinformatics Insights on Viral Gene Expression Transactivation: From HIV-1 to SARS-CoV-2.
Autorzy:: Patarca R; ACCESS Health International, 384 West Lane, Ridgefield, CT 06877, USA.; Feinstein Institutes for Medical Research, 350 Community Dr, Manhasset, NY 11030, USA.
Haseltine WA; ACCESS Health International, 384 West Lane, Ridgefield, CT 06877, USA.; Feinstein Institutes for Medical Research, 350 Community Dr, Manhasset, NY 11030, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 16; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: HIV-1*/physiology
COVID-19*/genetics
Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Transcriptional Activation ; HIV Long Terminal Repeat ; Gene Products, tat/genetics ; Lentivirus/genetics ; Gene Expression ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; RNA, Viral/metabolism

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Skocz do pozycji: 6.

Tytuł:: Role of HIV-1 Tat Protein Interactions with Host Receptors in HIV Infection and Pathogenesis.
Autorzy:: Cafaro, Aurelio (AUTHOR)
Schietroma, Ivan (AUTHOR)
Sernicola, Leonardo (AUTHOR)
Belli, Roberto (AUTHOR)
Campagna, Massimo (AUTHOR)
Mancini, Flavia (AUTHOR)
Farcomeni, Stefania (AUTHOR)
Pavone-Cossut, Maria Rosaria (AUTHOR)
Borsetti, Alessandra (AUTHOR)
Monini, Paolo (AUTHOR)
Ensoli, Barbara (AUTHOR); Pokaż więcej
Źródło:: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 3, p1704. 23p.

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Skocz do pozycji: 7.

Tytuł:: Features of Tat Protein in HIV-1 Sub-Subtype A6 Variants Circulating in the Moscow Region, Russia.
Autorzy:: Kuznetsova A; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Kim K; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Tumanov A; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Munchak I; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Antonova A; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Lebedev A; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.; Mechnikov Scientific Research Institute of Vaccines and Serums, 105064 Moscow, Russia.
Ozhmegova E; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Orlova-Morozova E; Moscow Regional Center for the Prevention and Control of AIDS and Infectious Diseases, 129110 Moscow, Russia.
Drobyshevskaya E; Moscow Regional Center for the Prevention and Control of AIDS and Infectious Diseases, 129110 Moscow, Russia.
Pronin A; Moscow Regional Center for the Prevention and Control of AIDS and Infectious Diseases, 129110 Moscow, Russia.
Prilipov A; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.
Kazennova E; Gamaleya National Research Center for Epidemiology and Microbiology, 123098 Moscow, Russia.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Nov 04; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 04.
Typ publikacji:: Journal Article
MeSH Terms:: HIV-1*/genetics
HIV-1*/metabolism
HIV Infections*/epidemiology
Humans ; Gene Products, tat/metabolism ; Moscow/epidemiology ; Russia/epidemiology ; tat Gene Products, Human Immunodeficiency Virus/genetics

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Skocz do pozycji: 8.

Tytuł:: Tat-malate dehydrogenase fusion protein protects neurons from oxidative and ischemic damage by reduction of reactive oxygen species and modulation of glutathione redox system.
Autorzy:: Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Kang MS; Department of Anatomy, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, 24341, South Korea.
Choi JH; Department of Anatomy, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, 24341, South Korea.
Moon SM; Department of Neurosurgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, 07441, South Korea.; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, 24253, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Apr 06; Vol. 13 (1), pp. 5653. Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Products, tat*/pharmacology
Ischemia*/drug therapy
Malate Dehydrogenase*/pharmacology
Neuroprotective Agents*/pharmacology
Oxidative Stress*/drug effects
Animals ; Gerbillinae ; Hippocampus/metabolism ; Hydrogen Peroxide/metabolism ; Neurons/metabolism ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/pharmacology ; Mice

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Skocz do pozycji: 9.

Tytuł:: Depressive-like Behavior Is Accompanied by Prefrontal Cortical Innate Immune Fatigue and Dendritic Spine Losses after HIV-1 Tat and Morphine Exposure.
Autorzy:: Nass SR; Department of Pharmacology and Toxicology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0613, USA.
Hahn YK; Department of Anatomy and Neurobiology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0709, USA.
Ohene-Nyako M; Department of Pharmacology and Toxicology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0613, USA.
McLane VD; Department of Pharmacology and Toxicology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0613, USA.
Damaj MI; Department of Pharmacology and Toxicology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0613, USA.
Thacker LR 2nd; Department of Biostatistics, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23219, USA.
Knapp PE; Department of Pharmacology and Toxicology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0613, USA.; Department of Anatomy and Neurobiology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0709, USA.; Institute for Drug and Alcohol Studies, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0059, USA.
Hauser KF; Department of Pharmacology and Toxicology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0613, USA.; Department of Anatomy and Neurobiology, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0709, USA.; Institute for Drug and Alcohol Studies, Medical College of Virginia (MCV) Campus, Virginia Commonwealth University, Richmond, VA 23298-0059, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Feb 21; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Depression*/chemically induced
Depression*/immunology
Prefrontal Cortex*/immunology
Immunity, Innate*
Dendritic Spines*/pathology
tat Gene Products, Human Immunodeficiency Virus*/adverse effects
Morphine*/adverse effects
Male ; Animals ; Mice ; Behavior, Animal ; Cytokines/immunology ; Interleukin-10/immunology ; Neuroinflammatory Diseases ; Mice, Transgenic ; Opioid-Related Disorders ; HIV Infections ; Analgesics, Opioid/adverse effects

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Skocz do pozycji: 10.

Tytuł:: The HIV-1 Integrase C-Terminal Domain Induces TAR RNA Structural Changes Promoting Tat Binding.
Autorzy:: Rocchi C; Molecular Microbiology and Structural Biochemistry, MMSB-IBCP, UMR 5086, CNRS, University of Lyon, 7 Passage du Vercors, CEDEX 07, 69367 Lyon, France.
Louvat C; Molecular Microbiology and Structural Biochemistry, MMSB-IBCP, UMR 5086, CNRS, University of Lyon, 7 Passage du Vercors, CEDEX 07, 69367 Lyon, France.
Miele AE; Institute of Analytical Sciences, UMR 5280 CNRS UCBL University of Lyon, 5 Rue de la Doua, 69100 Villeurbanne, France.; Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.
Batisse J; Chromatin Stability and DNA Mobility, Department of Integrated Structural Biology, IGBMC, CNRS, UMR 7104-Inserm U 158, University of Strasbourg, 1 rue Laurent Fries, 67404 Illkirch, France.
Guillon C; Molecular Microbiology and Structural Biochemistry, MMSB-IBCP, UMR 5086, CNRS, University of Lyon, 7 Passage du Vercors, CEDEX 07, 69367 Lyon, France.
Ballut L; Molecular Microbiology and Structural Biochemistry, MMSB-IBCP, UMR 5086, CNRS, University of Lyon, 7 Passage du Vercors, CEDEX 07, 69367 Lyon, France.
Lener D; RNA Architecture and Reactivity, IBMC, CNRS, UPR 9002, University of Strasbourg, 2, Allée Konrad Roentgen, 67084 Strasbourg, France.
Negroni M; RNA Architecture and Reactivity, IBMC, CNRS, UPR 9002, University of Strasbourg, 2, Allée Konrad Roentgen, 67084 Strasbourg, France.
Ruff M; Chromatin Stability and DNA Mobility, Department of Integrated Structural Biology, IGBMC, CNRS, UMR 7104-Inserm U 158, University of Strasbourg, 1 rue Laurent Fries, 67404 Illkirch, France.
Gouet P; Molecular Microbiology and Structural Biochemistry, MMSB-IBCP, UMR 5086, CNRS, University of Lyon, 7 Passage du Vercors, CEDEX 07, 69367 Lyon, France.
Fiorini F; Molecular Microbiology and Structural Biochemistry, MMSB-IBCP, UMR 5086, CNRS, University of Lyon, 7 Passage du Vercors, CEDEX 07, 69367 Lyon, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 08; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 08.
Typ publikacji:: Journal Article
MeSH Terms:: tat Gene Products, Human Immunodeficiency Virus*/genetics
HIV Integrase*/genetics
RNA, Viral/genetics ; RNA, Viral/metabolism ; Transcription Factors

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Skocz do pozycji: 11.

Tytuł:: HIV gp120/Tat protein-induced epithelial-mesenchymal transition promotes the progression of cervical lesions.
Autorzy:: Wang P; Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Yang B; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Huang H; Department of Intensive Care Unit, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Liang P; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Long B; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Chen L; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Yang L; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Tang L; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China.
Huang L; Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. .
Liang H; Department of Gynecology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510000, China. .; Pokaż więcej
Źródło:: AIDS research and therapy [AIDS Res Ther] 2023 Nov 19; Vol. 20 (1), pp. 82. Date of Electronic Publication: 2023 Nov 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Uterine Cervical Neoplasms*/genetics
Uterine Cervical Neoplasms*/metabolism
Uterine Cervical Neoplasms*/pathology
HIV Infections*
Female ; Humans ; beta Catenin/genetics ; beta Catenin/metabolism ; beta Catenin/pharmacology ; Cell Line, Tumor ; Gene Products, tat/pharmacology ; Epithelial-Mesenchymal Transition/physiology

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Skocz do pozycji: 12.

Tytuł:: Dual effect of TAT functionalized DHAH lipid nanoparticles with neurotrophic factors in human BBB and microglia cultures.
Autorzy:: Hernando S; Center for the Advancement of Integrated Medical and Engineering Sciences (AIMES), Karolinska Institutet and KTH Royal Institute of Technology, 171 77, Stockholm, Sweden.; Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.; NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006, Vitoria-Gasteiz, Spain.; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029, Madrid, Spain.; Bioaraba, NanoBioCel Research Group, 01006, Vitoria-Gasteiz, Spain.
Nikolakopoulou P; Center for the Advancement of Integrated Medical and Engineering Sciences (AIMES), Karolinska Institutet and KTH Royal Institute of Technology, 171 77, Stockholm, Sweden.; Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
Voulgaris D; Center for the Advancement of Integrated Medical and Engineering Sciences (AIMES), Karolinska Institutet and KTH Royal Institute of Technology, 171 77, Stockholm, Sweden.; Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.; Division of Nanobiotechnology, Department of Protein Science, Science for Life Laboratory, KTH Royal Institute of Technology, Solna, Sweden.; Division of Micro and Nanosystems, KTH Royal Institute of Technology, 171 77, Stockholm, Sweden.
Hernandez RM; NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006, Vitoria-Gasteiz, Spain.; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029, Madrid, Spain.; Bioaraba, NanoBioCel Research Group, 01006, Vitoria-Gasteiz, Spain.
Igartua M; NanoBioCel Research Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006, Vitoria-Gasteiz, Spain. .; Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, 28029, Madrid, Spain. .; Bioaraba, NanoBioCel Research Group, 01006, Vitoria-Gasteiz, Spain. .
Herland A; Center for the Advancement of Integrated Medical and Engineering Sciences (AIMES), Karolinska Institutet and KTH Royal Institute of Technology, 171 77, Stockholm, Sweden. .; Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden. .; Division of Nanobiotechnology, Department of Protein Science, Science for Life Laboratory, KTH Royal Institute of Technology, Solna, Sweden. .; Pokaż więcej
Źródło:: Fluids and barriers of the CNS [Fluids Barriers CNS] 2022 Mar 17; Vol. 19 (1), pp. 22. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:: Journal Article
MeSH Terms:: Blood-Brain Barrier*/metabolism
Nanoparticles*
Nerve Growth Factors*/administration & dosage
Neurodegenerative Diseases*/drug therapy
tat Gene Products, Human Immunodeficiency Virus*/chemistry
Docosahexaenoic Acids/chemistry ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Liposomes ; Microglia/metabolism

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Skocz do pozycji: 13.

Tytuł:: HIV-1 Tat and Heparan Sulfate Proteoglycans Orchestrate the Setup of in Cis and in Trans Cell-Surface Interactions Functional to Lymphocyte Trans-Endothelial Migration.
Autorzy:: Urbinati C; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Milanesi M; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Lauro N; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Bertelli C; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
David G; Department of Human Genetics, University of Leuven, B-3000 Leuven, Belgium.
D'Ursi P; Institute for Biomedical Technologies, National Research Council (ITB-CNR), 20090 Segrate, Italy.
Rusnati M; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Chiodelli P; Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 10; Vol. 26 (24). Date of Electronic Publication: 2021 Dec 10.
Typ publikacji:: Journal Article
MeSH Terms:: Endothelium/*metabolism
Heparan Sulfate Proteoglycans/*metabolism
Lymphocytes/*metabolism
tat Gene Products, Human Immunodeficiency Virus/*metabolism
Cell Adhesion ; Cell Movement ; Endothelium/chemistry ; Heparan Sulfate Proteoglycans/chemistry ; Humans ; Lymphocytes/chemistry ; Models, Molecular ; Molecular Structure ; Stereoisomerism ; Tumor Cells, Cultured ; tat Gene Products, Human Immunodeficiency Virus/chemistry

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Skocz do pozycji: 14.

Tytuł:: Targeting Tat-TAR RNA Interaction for HIV-1 Inhibition.
Autorzy:: Alanazi A; Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA.
Ivanov A; Center for Sickle Cell Disease, College of Medicine, Howard University, Washington, DC 20059, USA.
Kumari N; Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA.
Lin X; Center for Sickle Cell Disease, College of Medicine, Howard University, Washington, DC 20059, USA.; Department of Oral and Maxillofacial Pathology, College of Dentistry, Howard University, Washington, DC 20059, USA.
Wang S; Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA.
Kovalskyy D; Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229, USA.
Nekhai S; Department of Microbiology, College of Medicine, Howard University, Washington, DC 20059, USA.; Center for Sickle Cell Disease, College of Medicine, Howard University, Washington, DC 20059, USA.; Department of Medicine, College of Medicine, Howard University, Washington, DC 20059, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Oct 06; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: HIV Infections/*prevention & control
HIV Long Terminal Repeat/*genetics
tat Gene Products, Human Immunodeficiency Virus/*genetics
Cyclin T/metabolism ; Cyclin-Dependent Kinase 9/metabolism ; Gene Expression/genetics ; Gene Expression Regulation, Viral/genetics ; HEK293 Cells ; HIV Infections/genetics ; HIV Long Terminal Repeat/drug effects ; HIV Long Terminal Repeat/physiology ; HIV-1/genetics ; HIV-1/metabolism ; HIV-1/pathogenicity ; Humans ; Leukocytes, Mononuclear/metabolism ; Molecular Docking Simulation ; Phosphorylation ; Protein Binding/drug effects ; RNA, Viral/genetics ; Small Molecule Libraries/pharmacology ; Virus Replication/drug effects ; tat Gene Products, Human Immunodeficiency Virus/drug effects ; tat Gene Products, Human Immunodeficiency Virus/metabolism

Czasopismo naukowe

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Skocz do pozycji: 15.

Tytuł:: Complex Formation of an RNA Aptamer with a Part of HIV-1 Tat through Induction of Base Triples in Living Human Cells Proven by In-Cell NMR.
Autorzy:: Eladl O; Structural Energy Bioscience Research Section, Institute of Advanced Energy, Kyoto University, Kyoto 611-0011, Japan.; Graduate School of Energy Science, Kyoto University, Kyoto 606-8501, Japan.; Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Yamaoki Y; Structural Energy Bioscience Research Section, Institute of Advanced Energy, Kyoto University, Kyoto 611-0011, Japan.; Graduate School of Energy Science, Kyoto University, Kyoto 606-8501, Japan.; Integrated Research Center for Carbon Negative Science, Institute of Advanced Energy, Kyoto University, Uji 611-0011, Japan.
Kondo K; Structural Energy Bioscience Research Section, Institute of Advanced Energy, Kyoto University, Kyoto 611-0011, Japan.; Integrated Research Center for Carbon Negative Science, Institute of Advanced Energy, Kyoto University, Uji 611-0011, Japan.; Biomass Product Tree Industry-Academia Collaborative Research Laboratory, Kyoto University, Kyoto 611-0011, Japan.
Nagata T; Structural Energy Bioscience Research Section, Institute of Advanced Energy, Kyoto University, Kyoto 611-0011, Japan.; Graduate School of Energy Science, Kyoto University, Kyoto 606-8501, Japan.; Integrated Research Center for Carbon Negative Science, Institute of Advanced Energy, Kyoto University, Uji 611-0011, Japan.
Katahira M; Structural Energy Bioscience Research Section, Institute of Advanced Energy, Kyoto University, Kyoto 611-0011, Japan.; Graduate School of Energy Science, Kyoto University, Kyoto 606-8501, Japan.; Integrated Research Center for Carbon Negative Science, Institute of Advanced Energy, Kyoto University, Uji 611-0011, Japan.; Biomass Product Tree Industry-Academia Collaborative Research Laboratory, Kyoto University, Kyoto 611-0011, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 22; Vol. 24 (10). Date of Electronic Publication: 2023 May 22.
Typ publikacji:: Journal Article
MeSH Terms:: Aptamers, Nucleotide*/chemistry
HIV-1*/metabolism
Humans ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; Nucleic Acid Conformation ; Magnetic Resonance Spectroscopy ; RNA, Viral/genetics

Czasopismo naukowe

na półce

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Skocz do pozycji: 16.

Tytuł:: Inactivation of HIV-1 in Polarized Infant Tonsil Epithelial Cells by Human Beta-Defensins 2 and 3 Tagged with the Protein Transduction Domain of HIV-1 Tat.
Autorzy:: Herrera R; Department of Medicine, University of California-San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.
Rosbe K; Department of Otolaryngology, University of California-San Francisco, San Francisco, CA 94115, USA.
Tugizov SM; Department of Medicine, University of California-San Francisco, 513 Parnassus Ave., San Francisco, CA 94143, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Oct 11; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 11.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Cell Polarity/*physiology
Epithelial Cells/*virology
HIV-1/*physiology
Palatine Tonsil/*virology
beta-Defensins/*metabolism
tat Gene Products, Human Immunodeficiency Virus/*metabolism
CD4-Positive T-Lymphocytes ; Endocytosis ; Epithelium ; HIV Infections ; Humans ; Infectious Disease Transmission, Vertical ; Macrophages/virology ; Mucous Membrane/virology ; Protein Domains ; beta-Defensins/genetics ; tat Gene Products, Human Immunodeficiency Virus/chemistry

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na półce

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Skocz do pozycji: 17.

Tytuł:: TAR RNA Mediated Folding of a Single-Arginine-Mutant HIV-1 Tat Protein within HeLa Cells Experiencing Intracellular Crowding.
Autorzy:: Kim JM; Division of Interdisciplinary Program in Precision Public Health (BK21 FOUR Program), Department of Biomedical Engineering, Korea University 145 Anam-ro, Seongbuk-gu, Seoul 02842, Korea.
Chun H; Division of Interdisciplinary Program in Precision Public Health (BK21 FOUR Program), Department of Biomedical Engineering, Korea University 145 Anam-ro, Seongbuk-gu, Seoul 02842, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 16; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 16.
Typ publikacji:: Journal Article
MeSH Terms:: tat Gene Products, Human Immunodeficiency Virus/*metabolism
Amino Acid Sequence ; HeLa Cells ; Humans ; Kinetics ; Microscopy, Fluorescence ; Mutagenesis, Site-Directed ; Mutant Proteins/genetics ; Protein Binding/genetics ; tat Gene Products, Human Immunodeficiency Virus/genetics

Czasopismo naukowe

na półce

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Skocz do pozycji: 18.

Tytuł:: Loss of In Vivo Replication Fitness of HIV-1 Variants Resistant to the Tat Inhibitor, dCA.
Autorzy:: Ling L; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Leda AR; Department of Immunology and Microbiology, University of Florida Scripps Biomedical Research, Jupiter, FL 33458, USA.
Begum N; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Spagnuolo RA; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Wahl A; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Garcia JV; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Valente ST; Department of Immunology and Microbiology, University of Florida Scripps Biomedical Research, Jupiter, FL 33458, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Apr 12; Vol. 15 (4). Date of Electronic Publication: 2023 Apr 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: HIV Infections*/drug therapy
HIV-1*/physiology
HIV Seropositivity*
Mice ; Animals ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; Virus Replication ; HIV Long Terminal Repeat

Czasopismo naukowe

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Skocz do pozycji: 19.

Tytuł:: Accurate Prediction of Transcriptional Activity of Single Missense Variants in HIV Tat with Deep Learning.
Autorzy:: Derbel H; Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.
Giacoletto CJ; School of Life Sciences, College of Sciences, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.
Benjamin R; Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.; School of Life Sciences, College of Sciences, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.
Chen G; Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.
Schiller MR; Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.; School of Life Sciences, College of Sciences, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.
Liu Q; Nevada Institute of Personalized Medicine, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.; School of Life Sciences, College of Sciences, University of Nevada Las Vegas, 4505 S Maryland Pkwy, Las Vegas, NV 89154, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 24; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 24.
Typ publikacji:: Journal Article
MeSH Terms:: Acquired Immunodeficiency Syndrome*
Deep Learning*
Humans ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; Transcriptional Activation ; Mutation, Missense ; Transcription, Genetic

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Skocz do pozycji: 20.

Tytuł:: HIV-1 Tat amino acid residues that influence Tat-TAR binding affinity: a scoping review.
Autorzy:: Gotora PT; Human Metabolomics, North-West University, Potchefstroom, South Africa.
van der Sluis R; Human Metabolomics, North-West University, Potchefstroom, South Africa.
Williams ME; Human Metabolomics, North-West University, Potchefstroom, South Africa. .; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2023 Mar 17; Vol. 23 (1), pp. 164. Date of Electronic Publication: 2023 Mar 17.
Typ publikacji:: Review; Journal Article
MeSH Terms:: HIV-1*/genetics
Humans ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; HIV Long Terminal Repeat ; Amino Acids/genetics ; Amino Acids/metabolism ; RNA, Viral/metabolism

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