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Wyszukujesz frazę ""thermogenesis"" wg kryterium: Temat


Starter badań:

Tytuł :
NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ.
Autorzy :
Huang J; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Linares JF; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Duran A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Xia W; Division of Metabolism and Endocrinology, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
Saltiel AR; Division of Metabolism and Endocrinology, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
Müller TD; Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Centre Munich, Oberschleißheim, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, Tübingen, Germany.
Diaz-Meco MT; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
Moscat J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. .; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 17; Vol. 12 (1), pp. 2876. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Thermogenesis*
Adipocytes/*metabolism
Intracellular Signaling Peptides and Proteins/*deficiency
PPAR gamma/*metabolism
Sequestosome-1 Protein/*deficiency
Adipose Tissue, Brown/cytology ; Adipose Tissue, Brown/metabolism ; Animals ; Animals, Newborn ; Cell Nucleus/metabolism ; Cells, Cultured ; Energy Metabolism/genetics ; HEK293 Cells ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; PPAR gamma/genetics ; Protein Binding ; Retinoid X Receptor alpha/genetics ; Retinoid X Receptor alpha/metabolism ; Sequestosome-1 Protein/genetics
Czasopismo naukowe
Tytuł :
Defining the lineage of thermogenic perivascular adipose tissue.
Autorzy :
Angueira AR; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Sakers AP; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Holman CD; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Cheng L; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Arbocco MN; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Shamsi F; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Lynes MD; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Shrestha R; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Renal Electrolyte and Hypertension Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Okada C; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Batmanov K; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Susztak K; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Renal Electrolyte and Hypertension Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Tseng YH; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Liaw L; Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME, USA.
Seale P; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. .; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. .
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Źródło :
Nature metabolism [Nat Metab] 2021 Apr; Vol. 3 (4), pp. 469-484. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Adipocytes, Brown/*physiology
Adipose Tissue, Brown/*physiology
Cell Lineage/*physiology
Thermogenesis/*physiology
Adipocytes, White/physiology ; Adipogenesis/physiology ; Adipose Tissue, Brown/growth & development ; Animals ; Animals, Newborn ; Aorta/cytology ; Aorta/physiology ; Blood Vessels/physiology ; Cell Lineage/genetics ; Fibroblasts/physiology ; Gene Expression Regulation/physiology ; Humans ; Infant, Newborn ; Mice ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/physiology ; Stem Cells/physiology ; Thermogenesis/genetics
Czasopismo naukowe
Tytuł :
Skeletal muscle non-shivering thermogenesis as an attractive strategy to combat obesity.
Autorzy :
Li H; Institute of Pharmacology, Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, PR China; Section of Endocrinology, School of Medicine, Yale University, New Haven 06520, USA. Electronic address: .
Wang C; Institute of Pharmacology, Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, PR China.
Li L; Institute of Pharmacology, Department of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, PR China.
Li L; Zhejiang Starry Pharmaceutical Co., Ltd., Taizhou 317306, PR China.
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119024. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Thermogenesis*/drug effects
Muscle, Skeletal/*physiopathology
Obesity/*physiopathology
Adenosine Triphosphate/metabolism ; Animals ; Biological Products/chemistry ; Biological Products/pharmacology ; Biological Products/therapeutic use ; Humans ; Muscle, Skeletal/drug effects ; Obesity/drug therapy ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism
Czasopismo naukowe
Tytuł :
Network pharmacology-based research uncovers cold resistance and thermogenesis mechanism of Cinnamomum cassia.
Autorzy :
Xiang-Li; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang 110840, China.
Bo-Xing; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xin-Liu; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Jiang XW; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Lu HY; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xu ZH; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yue-Yang; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Qiong-Wu; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Dong-Yao; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang 110840, China.
Zhang YS; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhao QC; Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang 110016, China; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang 110840, China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2021 Mar; Vol. 149, pp. 104824. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Thermogenesis*
Adipose Tissue, Brown/*drug effects
Cinnamomum aromaticum/*chemistry
Drugs, Chinese Herbal/*pharmacology
Plant Extracts/*pharmacology
Acrolein/analogs & derivatives ; Acrolein/pharmacology ; Animals ; Cells, Cultured ; Cold Temperature ; Gene Expression Regulation ; Gene Ontology ; Male ; Membrane Potential, Mitochondrial ; Mice ; Molecular Structure ; Protein Interaction Maps ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production.
Autorzy :
Zhou H; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China. .
Peng X; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Hu J; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Wang L; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Luo H; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Zhang J; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Zhang Y; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Li G; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Ji Y; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Zhang J; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Bai J; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Liu M; Department of Biochemistry and Molecular Biology, University of New Mexico Health Sciences Center, Albuquerque, NM, 87131, USA.
Zhou Z; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China.
Liu F; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, 410011, Changsha, Hunan, China. .; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 12; Vol. 12 (1), pp. 326. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet, High-Fat*
Thermogenesis*/drug effects
Thermogenesis*/genetics
Glutathione Transferase/*deficiency
Interferon-gamma/*biosynthesis
T-Lymphocytes/*metabolism
Adipocytes, Brown/drug effects ; Adipocytes, Brown/metabolism ; Adipose Tissue, Brown/drug effects ; Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/drug effects ; Adipose Tissue, White/metabolism ; Animals ; Down-Regulation/drug effects ; Energy Metabolism/drug effects ; Feeding Behavior ; Glutathione Transferase/metabolism ; Insulin Resistance ; Interferon-gamma/administration & dosage ; Interferon-gamma/pharmacology ; Male ; Mice, Knockout ; Mitochondria/drug effects ; Mitochondria/metabolism ; Obesity/genetics ; Obesity/pathology ; T-Lymphocytes/drug effects ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/metabolism ; Uncoupling Protein 1/metabolism
Czasopismo naukowe
Tytuł :
Bola3 Regulates Beige Adipocyte Thermogenesis via Maintaining Mitochondrial Homeostasis and Lipolysis.
Autorzy :
Bai N; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Ma J; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Alimujiang M; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Xu J; Department of Geriatrics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Hu F; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Xu Y; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Leng Q; Department of Endocrinology, Seventh People's Hospital of Shanghai University of TCM, Shanghai, China.
Chen S; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Li X; Department of Endocrinology, Seventh People's Hospital of Shanghai University of TCM, Shanghai, China.
Han J; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Jia W; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Bao Y; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yang Y; Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2021 Jan 11; Vol. 11, pp. 592154. Date of Electronic Publication: 2021 Jan 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Homeostasis*
Lipolysis*
Thermogenesis*
Adipocytes, Beige/*physiology
Mitochondria/*physiology
Mitochondrial Proteins/*metabolism
Adipocytes, Beige/cytology ; Adipose Tissue, White/cytology ; Adipose Tissue, White/physiology ; Animals ; Cell Differentiation ; Female ; Gene Expression Regulation ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondrial Proteins/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Leptin Modulates the Response of Brown Adipose Tissue to Negative Energy Balance: Implication of the GH/IGF-I Axis.
Autorzy :
Barrios V; Department of Endocrinology, Instituto de Investigación La Princesa, Hospital Infantil Universitario Niño Jesús, E-28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.
Frago LM; Department of Endocrinology, Instituto de Investigación La Princesa, Hospital Infantil Universitario Niño Jesús, E-28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.; Department of Pediatrics, Faculty of Medicine, Universidad Autónoma de Madrid, E-28029 Madrid, Spain.
Canelles S; Department of Endocrinology, Instituto de Investigación La Princesa, Hospital Infantil Universitario Niño Jesús, E-28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.
Guerra-Cantera S; Department of Endocrinology, Instituto de Investigación La Princesa, Hospital Infantil Universitario Niño Jesús, E-28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.; Department of Pediatrics, Faculty of Medicine, Universidad Autónoma de Madrid, E-28029 Madrid, Spain.
Arilla-Ferreiro E; Department of Biological Systems, Faculty of Medicine, Universidad de Alcalá, E-28871 Alcalá de Henares, Spain.
Chowen JA; Department of Endocrinology, Instituto de Investigación La Princesa, Hospital Infantil Universitario Niño Jesús, E-28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.; CEI UAM + CSIC, IMDEA Food Institute, E-28049 Madrid, Spain.
Argente J; Department of Endocrinology, Instituto de Investigación La Princesa, Hospital Infantil Universitario Niño Jesús, E-28009 Madrid, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain.; Department of Pediatrics, Faculty of Medicine, Universidad Autónoma de Madrid, E-28029 Madrid, Spain.; CEI UAM + CSIC, IMDEA Food Institute, E-28049 Madrid, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 11; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 11.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue, Brown/*drug effects
Energy Metabolism/*drug effects
Growth Hormone/*genetics
Insulin-Like Growth Factor I/*genetics
Leptin/*pharmacology
Thermogenesis/*drug effects
Adipose Tissue, Brown/metabolism ; Animals ; Cyclic AMP Response Element-Binding Protein/genetics ; Cyclic AMP Response Element-Binding Protein/metabolism ; Energy Metabolism/genetics ; Glucose Transporter Type 4/genetics ; Glucose Transporter Type 4/metabolism ; Growth Hormone/metabolism ; Hypothalamus/drug effects ; Hypothalamus/metabolism ; Injections, Intraventricular ; Insulin-Like Growth Factor I/metabolism ; Male ; Phosphorylation/drug effects ; Pituitary Gland/drug effects ; Pituitary Gland/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar ; Receptor, IGF Type 1/genetics ; Receptor, IGF Type 1/metabolism ; Somatostatin/genetics ; Somatostatin/metabolism ; Suppressor of Cytokine Signaling 3 Protein/genetics ; Suppressor of Cytokine Signaling 3 Protein/metabolism ; Thermogenesis/genetics ; Uncoupling Protein 1/genetics ; Uncoupling Protein 1/metabolism
Czasopismo naukowe
Tytuł :
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Autorzy :
Shi M; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Huang XY; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Ren XY; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Wei XY; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Ma Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Lin ZZ; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Liu DT; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Song L; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Zhao TJ; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Li G; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Yao L; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Zhu M; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Zhang C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Xie C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Wu Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Wu HM; Department of Neurology, First Affiliated Hospital, Xiamen University, Xiamen, China.
Fan LP; Department of Neurology, First Affiliated Hospital, Xiamen University, Xiamen, China.
Ou J; Department of Hepatic Surgery and Liver Transplantation Centre of the Third Affiliated Hospital, Guangdong Province Engineering Laboratory for Transplantation Medicine, Guangzhou, China.
Zhan YH; Department of Neurology, First Affiliated Hospital, Xiamen University, Xiamen, China.
Lin SY; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China. .; Department of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, China. .
Lin SC; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2021 Mar; Vol. 23 (3), pp. 268-277. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Thermogenesis*
Adipocytes, Brown/*metabolism
Adipose Tissue, Brown/*innervation
Phospholipid Transfer Proteins/*metabolism
Sympathetic Nervous System/*physiology
Uncoupling Protein 1/*metabolism
Adiponectin/genetics ; Adiponectin/metabolism ; Animals ; Cells, Cultured ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Energy Metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Oxidation-Reduction ; Phospholipid Transfer Proteins/deficiency ; Phospholipid Transfer Proteins/genetics ; Phosphorylation ; Signal Transduction ; Uncoupling Protein 1/deficiency ; Uncoupling Protein 1/genetics
Czasopismo naukowe
Tytuł :
Creatine kinase B controls futile creatine cycling in thermogenic fat.
Autorzy :
Rahbani JF; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Roesler A; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Hussain MF; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Samborska B; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Dykstra CB; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Tsai L; Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Jedrychowski MP; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Vergnes L; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Reue K; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Spiegelman BM; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Kazak L; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada. .; Department of Biochemistry, McGill University, Montreal, Quebec, Canada. .
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Źródło :
Nature [Nature] 2021 Feb; Vol. 590 (7846), pp. 480-485. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Thermogenesis*
Adipose Tissue/*metabolism
Creatine/*metabolism
Creatine Kinase, BB Form/*metabolism
Adipocytes/metabolism ; Adipose Tissue/cytology ; Adipose Tissue/enzymology ; Animals ; Creatine Kinase, BB Form/deficiency ; Creatine Kinase, BB Form/genetics ; Cyclic AMP/metabolism ; Energy Metabolism/genetics ; Female ; Glucose/metabolism ; Homeostasis ; Humans ; Male ; Mice ; Mitochondria/metabolism ; Obesity/enzymology ; Obesity/genetics ; Obesity/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Withaferin A exerts an anti-obesity effect by increasing energy expenditure through thermogenic gene expression in high-fat diet-fed obese mice.
Autorzy :
Lee DH; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea.
Park SH; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea.
Lee E; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea.
Seo HD; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea.
Ahn J; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea.
Jang YJ; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea.
Ha TY; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea.
Im SS; Department of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.
Jung CH; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeonbuk 55365, Republic of Korea; Department of Food Biotechnology, Korea University of Science and Technology, Daejeon 34113, Republic of Korea. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Feb; Vol. 82, pp. 153457. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article
MeSH Terms :
Diet, High-Fat*
Anti-Obesity Agents/*pharmacology
Energy Metabolism/*drug effects
Gene Expression/*drug effects
Obesity/*drug therapy
Thermogenesis/*drug effects
Withanolides/*therapeutic use
AMP-Activated Protein Kinases/metabolism ; Adipose Tissue, Brown/drug effects ; Adipose Tissue, Brown/metabolism ; Adipose Tissue, White/drug effects ; Adipose Tissue, White/metabolism ; Animals ; Body Weight/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Mitochondria/metabolism ; Thermogenesis/genetics ; Uncoupling Protein 1/metabolism ; Withania/chemistry ; Withanolides/pharmacology
Czasopismo naukowe
Tytuł :
Adipocyte Microenvironment: Everybody in the Neighborhood Talks about the Temperature.
Autorzy :
Shamsi F; Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA.
Tseng YH; Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA.
Kahn CR; Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA. Electronic address: .
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Źródło :
Cell metabolism [Cell Metab] 2021 Jan 05; Vol. 33 (1), pp. 4-6.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
RNA, Small Nuclear*
Thermogenesis*
Adipocytes ; Adipose Tissue ; Temperature
Czasopismo naukowe
Tytuł :
Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes.
Autorzy :
Duan YN; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Ge X; School of Pharmacy, Nantong University, Nantong, China.
Jiang HW; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Zhang HJ; School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, People's Republic of China.
Zhao Y; School of Pharmacy, Nantong University, Nantong, China.
Li JL; School of Pharmacy, Nantong University, Nantong, China.; School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, People's Republic of China.
Zhang W; Kay Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, School of Life Science, East China Normal University, Shanghai, China.
Li JY; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2020 Dec 10; Vol. 11, pp. 592818. Date of Electronic Publication: 2020 Dec 10 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Thermogenesis*
Adipocytes, Beige/*drug effects
Adipocytes, Brown/*drug effects
Benzodioxoles/*pharmacology
Diet, High-Fat/*adverse effects
Lignans/*pharmacology
Obesity/*drug therapy
Adipocytes, Beige/cytology ; Adipocytes, Brown/cytology ; Animals ; Energy Metabolism ; Insulin Resistance ; Male ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/drug effects ; Mice ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Obesity/etiology ; Obesity/pathology
Czasopismo naukowe
Tytuł :
Insulin Modulates the Bioenergetic and Thermogenic Capacity of Rat Brown Adipocytes In Vivo by Modulating Mitochondrial Mosaicism.
Autorzy :
Golic I; Center for Electron Microscopy, Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.
Kalezic A; Institute for Biological Research 'Sinisa Stankovic'-National Institute of Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Jankovic A; Institute for Biological Research 'Sinisa Stankovic'-National Institute of Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Jonic S; IMPMC-UMR CNRS 7590, Sorbonne Université, Muséum National d'Histoire Naturelle, 75005 Paris, France.
Korac B; Institute for Biological Research 'Sinisa Stankovic'-National Institute of Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Korac A; Center for Electron Microscopy, Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 03; Vol. 21 (23). Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
Energy Metabolism*/drug effects
Thermogenesis*/drug effects
Thermogenesis*/genetics
Adipocytes, Brown/*metabolism
Insulin/*metabolism
Mitochondria/*metabolism
Adipocytes, Brown/drug effects ; Adipose Tissue, Brown/metabolism ; Animals ; Biomarkers ; Electron Transport Chain Complex Proteins/genetics ; Electron Transport Chain Complex Proteins/metabolism ; Enzyme Activation ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fluorescent Antibody Technique ; Gene Expression ; Insulin/pharmacology ; Mice ; Mitochondria/drug effects ; Mitochondria/genetics ; Mitochondria/ultrastructure ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Mitochondrial Proton-Translocating ATPases/metabolism ; Mosaicism ; Rats
Czasopismo naukowe
Tytuł :
Panax ginseng root, not leaf, can enhance thermogenic capacity and mitochondrial function in mice.
Autorzy :
Wu SH; He-Nan University of Chinese Medicine, Zheng-Zhou, China.
Li HB; He-Nan University of Chinese Medicine, Zheng-Zhou, China.
Li GL; Basic Medical College, He-Nan University of Chinese Medicine, Zheng-Zhou, China.
Qi YJ; He-Nan University of Chinese Medicine, Zheng-Zhou, China.
Zhang J; Basic Medical College, He-Nan University of Chinese Medicine, Zheng-Zhou, China.
Wang BY; Basic Medical College, He-Nan University of Chinese Medicine, Zheng-Zhou, China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 374-384.
Typ publikacji :
Journal Article
MeSH Terms :
Panax*
Plant Leaves*
Plant Roots*
Mitochondria/*drug effects
Plant Extracts/*pharmacology
Thermogenesis/*drug effects
Animals ; Energy Metabolism/drug effects ; Energy Metabolism/physiology ; Male ; Mice ; Mice, Inbred ICR ; Mitochondria/metabolism ; Plant Extracts/isolation & purification ; Thermogenesis/physiology
Czasopismo naukowe
Tytuł :
Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.
Autorzy :
Chitraju C; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Fischer AW; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Farese RV Jr; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: .
Walther TC; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2020 Nov 03; Vol. 33 (5), pp. 108348.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cold Temperature*
Thermogenesis*
Adipose Tissue, Brown/*metabolism
Lipid Droplets/*metabolism
Adaptation, Physiological ; Adipocytes, Beige/metabolism ; Adipocytes, Brown/metabolism ; Animals ; Diacylglycerol O-Acyltransferase/deficiency ; Diacylglycerol O-Acyltransferase/metabolism ; Diet, High-Fat ; Glucose Intolerance/pathology ; Mice, Knockout ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes.
Autorzy :
Yi D; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.; Endocrinology Program, University of California, Berkeley, Berkeley, United States.
Nguyen HP; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.; Endocrinology Program, University of California, Berkeley, Berkeley, United States.
Dinh J; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Viscarra JA; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Xie Y; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Lin F; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Zhu M; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Dempersmier JM; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Wang Y; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
Sul HS; Department of Nutritional Sciences & Toxicology, University of California, Berkeley, Berkeley, United States.
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Źródło :
ELife [Elife] 2020 Oct 27; Vol. 9. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Thermogenesis*
Histone-Lysine N-Methyltransferase/*metabolism
Uncoupling Protein 1/*metabolism
Adipose Tissue, Brown/cytology ; Adipose Tissue, Brown/metabolism ; Animals ; Cell Differentiation ; Energy Metabolism ; Histone-Lysine N-Methyltransferase/genetics ; Histones/metabolism ; Methylation ; Mice ; Mice, Knockout ; Promoter Regions, Genetic ; Protein Binding ; Uncoupling Protein 1/genetics
Czasopismo naukowe
Tytuł :
Editorial: Current Challenges for Targeting Brown Fat Thermogenesis to Combat Obesity.
Autorzy :
Yoneshiro T; Division of Metabolic Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.; Diabetes Center, University of California, San Francisco, San Francisco, CA, United States.
Rodríguez-Rodríguez R; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Barcelona, Spain.
Betz MJ; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel and University of Basel, Basel, Switzerland.
Rensen PCN; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, Netherlands.
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Źródło :
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2020 Oct 27; Vol. 11, pp. 600341. Date of Electronic Publication: 2020 Oct 27 (Print Publication: 2020).
Typ publikacji :
Editorial; Introductory Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Thermogenesis*
Adipose Tissue, Brown/*physiopathology
Obesity/*pathology
Humans ; Obesity/therapy
Czasopismo naukowe
Tytuł :
Transcriptional Factors of Thermogenic Adipocyte Development and Generation of Brown and Beige Adipocytes From Stem Cells.
Autorzy :
Van Nguyen TT; Stem Cell Institute, University of Science Ho Chi Minh City, Ho Chi Minh City, Viet Nam.; Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Viet Nam.
Vu VV; Stem Cell Institute, University of Science Ho Chi Minh City, Ho Chi Minh City, Viet Nam.; Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Viet Nam.
Pham PV; Stem Cell Institute, University of Science Ho Chi Minh City, Ho Chi Minh City, Viet Nam. .; Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Viet Nam. .; Laboratory of Stem Cell Research and Application, University of Science Ho Chi Minh City, Ho Chi Minh City, Viet Nam. .
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Źródło :
Stem cell reviews and reports [Stem Cell Rev Rep] 2020 Oct; Vol. 16 (5), pp. 876-892.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Thermogenesis*
Adipocytes, Beige/*cytology
Adipocytes, Brown/*cytology
Stem Cells/*cytology
Transcription Factors/*metabolism
Animals ; Cell Differentiation ; Humans
Czasopismo naukowe
Tytuł :
Characterization of brown adipose tissue thermogenesis in the naked mole-rat (Heterocephalus glaber), a heterothermic mammal.
Autorzy :
Oiwa Y; Department of Aging and Longevity Research, Kumamoto University, Kumamoto, 860-0811, Japan.; Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan.
Oka K; Department of Aging and Longevity Research, Kumamoto University, Kumamoto, 860-0811, Japan.
Yasui H; Laboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, 060-0818, Japan.; Central Institute of Isotope Science, Hokkaido University, Hokkaido, 060-0815, Japan.
Higashikawa K; Central Institute of Isotope Science, Hokkaido University, Hokkaido, 060-0815, Japan.; Laboratory of Integrated Molecular Imaging, Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Hokkaido, 060-0815, Japan.
Bono H; Program of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, 3-10-23 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-0046, Japan.
Kawamura Y; Department of Aging and Longevity Research, Kumamoto University, Kumamoto, 860-0811, Japan.
Miyawaki S; Laboratory of Veterinary Surgery, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
Watarai A; Laboratory of Human-Animal interaction and Reciprocity, School of Veterinary Medicine, Azabu University, Sagamihara, 252-5201, Japan.; Laboratory of Behavioral Neuroscience, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, 113-0032, Japan.
Kikusui T; Laboratory of Human-Animal interaction and Reciprocity, School of Veterinary Medicine, Azabu University, Sagamihara, 252-5201, Japan.
Shimizu A; Division of Biomedical Information Analysis, Institute for Biomedical Sciences, Iwate Medical University, Shiwa, 028-3694, Japan.
Okano H; Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Kuge Y; Central Institute of Isotope Science, Hokkaido University, Hokkaido, 060-0815, Japan.; Laboratory of Integrated Molecular Imaging, Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Hokkaido, 060-0815, Japan.
Kimura K; Laboratory of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, 060-0818, Japan.
Okamatsu-Ogura Y; Laboratory of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, 060-0818, Japan. .
Miura K; Department of Aging and Longevity Research, Kumamoto University, Kumamoto, 860-0811, Japan. .; Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan. .; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, 860-8556, Japan. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 10; Vol. 10 (1), pp. 19488. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue, Brown/*metabolism
Body Temperature/*physiology
Body Temperature Regulation/*physiology
Thermogenesis/*physiology
Adipose Tissue, Brown/diagnostic imaging ; Adipose Tissue, Brown/drug effects ; Adrenergic beta-3 Receptor Antagonists/pharmacology ; Animals ; Body Temperature/drug effects ; Body Temperature Regulation/genetics ; Cold Temperature ; Female ; Gene Expression Regulation/drug effects ; Male ; Mole Rats ; Norepinephrine/pharmacology ; Oxygen Consumption/drug effects ; Positron Emission Tomography Computed Tomography ; Propanolamines/pharmacology ; Receptors, Adrenergic, beta-3/metabolism ; Thermogenesis/genetics
Czasopismo naukowe
Tytuł :
Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice.
Autorzy :
Silvestri E; Department of Science and Technology, University of Sannio, Benevento, Italy.
Senese R; Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', Caserta, Italy.
De Matteis R; Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Urbino, Italy.
Cioffi F; Department of Science and Technology, University of Sannio, Benevento, Italy.
Moreno M; Department of Science and Technology, University of Sannio, Benevento, Italy.
Lanni A; Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', Caserta, Italy.
Gentile A; Department of Biology, University of Naples Federico II, Naples, Italy.
Busiello RA; Department of Biology, University of Naples Federico II, Naples, Italy.
Salzano AM; Proteomics & Mass Spectrometry Laboratory, ISPAAM, National Research Council, Naples, Italy.
Scaloni A; Proteomics & Mass Spectrometry Laboratory, ISPAAM, National Research Council, Naples, Italy.
de Lange P; Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', Caserta, Italy.
Goglia F; Department of Science and Technology, University of Sannio, Benevento, Italy.
Lombardi A; Department of Biology, University of Naples Federico II, Naples, Italy.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 15146-15163. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Oxidative Stress*
Thermogenesis*
Adipose Tissue, Brown/*pathology
Fatty Acids/*metabolism
Mitochondria/*pathology
Uncoupling Protein 3/*physiology
Adipose Tissue, Brown/metabolism ; Animals ; Energy Metabolism ; Female ; Homeostasis ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; Oxidation-Reduction
Czasopismo naukowe

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