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Tytuł :
Shen-Fu Decoction could ameliorate intestinal permeability by regulating the intestinal expression of tight junction proteins and p-VASP in septic rats.
Autorzy :
Liu F; Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, 100078, China.
Liu J; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Liu Y; First Clinical College of Hubei University of Medicine, Shiyan City, Hubei province, 442000, China.
Zhang Y; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Ding X; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 25; Vol. 268, pp. 113562. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Adhesion Molecules/*biosynthesis
Drugs, Chinese Herbal/*therapeutic use
Intestinal Mucosa/*drug effects
Microfilament Proteins/*biosynthesis
Phosphoproteins/*biosynthesis
Sepsis/*drug therapy
Tight Junction Proteins/*biosynthesis
Animals ; Cell Adhesion Molecules/antagonists & inhibitors ; Drugs, Chinese Herbal/pharmacology ; Gene Expression ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Male ; Microfilament Proteins/antagonists & inhibitors ; Permeability/drug effects ; Phosphoproteins/antagonists & inhibitors ; Rats ; Rats, Sprague-Dawley ; Sepsis/metabolism ; Sepsis/pathology ; Tight Junction Proteins/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Scutellaria baicalensis Georgi polysaccharide ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function and modulating gut microbiota.
Autorzy :
Cui L; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Guan X; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Ding W; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Luo Y; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Wang W; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Bu W; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Song J; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Tan X; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Sun E; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Ning Q; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Liu G; Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, PR China.
Jia X; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, Jiangsu, PR China. Electronic address: .
Feng L; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, Jiangsu, PR China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jan 01; Vol. 166, pp. 1035-1045. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis, Ulcerative/*drug therapy
Gastrointestinal Microbiome/*drug effects
Plant Extracts/*therapeutic use
Polysaccharides/*therapeutic use
Scutellaria baicalensis/*chemistry
Tight Junction Proteins/*metabolism
Animals ; Colitis, Ulcerative/etiology ; Colitis, Ulcerative/microbiology ; Cytokines/genetics ; Cytokines/metabolism ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Polysaccharides/chemistry ; Polysaccharides/pharmacology ; Sodium Dodecyl Sulfate/toxicity ; Tight Junction Proteins/genetics
Czasopismo naukowe
Tytuł :
Effects of treadmill exercise on the regulation of tight junction proteins in aged mice.
Autorzy :
Shin HE; Institute of Sport Science, Seoul National University, Seoul, South Korea.
Kwak SE; Institute of Sport Science, Seoul National University, Seoul, South Korea.
Zhang DD; Institute of Sport Science, Seoul National University, Seoul, South Korea.
Lee J; Institute of Sport Science, Seoul National University, Seoul, South Korea.
Yoon KJ; Institute of Sport Science, Seoul National University, Seoul, South Korea.
Cho HS; Institute of Sport Science, Seoul National University, Seoul, South Korea.
Moon HY; Institute of Sport Science, Seoul National University, Seoul, South Korea; Institute on Aging, Seoul National University, Seoul, South Korea.
Song W; Institute of Sport Science, Seoul National University, Seoul, South Korea; Institute on Aging, Seoul National University, Seoul, South Korea. Electronic address: .
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Źródło :
Experimental gerontology [Exp Gerontol] 2020 Nov; Vol. 141, pp. 111077. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intestinal Mucosa*
Tight Junction Proteins*
Animals ; Caco-2 Cells ; Humans ; Mice ; Mice, Inbred C57BL ; Occludin ; Zonula Occludens-1 Protein
Czasopismo naukowe
Tytuł :
Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells.
Autorzy :
Lee DC; Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Otorhinolaryngology-Head and Neck Surgery, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Choi H; Clinical Research Institute, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Oh JM; Clinical Research Institute, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Lee J; Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, 222, Banpo-daero, Seocho-gu, Seoul, Republic of Korea. Electronic address: .
Lee J; Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Otorhinolaryngology-Head and Neck Surgery, Daejeon St. Mary's Hospital, Daeheung-dong, Jung-gu, Daejeon, Republic of Korea. Electronic address: .
Lee HY; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: .
Kang JY; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 15; Vol. 333, pp. 33-41. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Air Pollutants/*toxicity
Epithelial Cells/*drug effects
Gene Expression Regulation/*drug effects
Nasal Mucosa/*drug effects
Oxidative Stress/*drug effects
Particulate Matter/*toxicity
Proto-Oncogene Proteins c-akt/*metabolism
Tight Junction Proteins/*metabolism
Acetylcysteine/pharmacology ; Cell Survival/drug effects ; Cells, Cultured ; Cytokines/genetics ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Female ; Humans ; Male ; Middle Aged ; Nasal Mucosa/metabolism ; Oxidative Stress/genetics ; Signal Transduction ; Tight Junction Proteins/genetics ; Tight Junctions/drug effects ; Tight Junctions/metabolism ; Turbinates/drug effects ; Turbinates/metabolism ; Urbanization
Czasopismo naukowe
Tytuł :
Channel functions of claudins in the organization of biological systems.
Autorzy :
Meoli L; Institute of Clinical Physiology/Nutritional Medicine, Medical Department, Division of Gastroenterology, Infectiology, Rheumatology, Charité - Universitätsmedizin Berlin, 12203 Berlin, Germany.
Günzel D; Institute of Clinical Physiology/Nutritional Medicine, Medical Department, Division of Gastroenterology, Infectiology, Rheumatology, Charité - Universitätsmedizin Berlin, 12203 Berlin, Germany. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Sep 01; Vol. 1862 (9), pp. 183344. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Claudins/*genetics
Tight Junction Proteins/*genetics
Tight Junctions/*genetics
Animals ; Claudins/chemistry ; Mutation/genetics ; Permeability ; Protein Isoforms/genetics ; Tight Junction Proteins/chemistry ; Tight Junctions/chemistry ; Vertebrates/genetics
Czasopismo naukowe
Tytuł :
Effect of High Glucose on Ocular Surface Epithelial Cell Barrier and Tight Junction Proteins.
Autorzy :
Alfuraih S; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, California, United States.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Northern Border University, Rafha, Saudi Arabia.
Barbarino A; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, California, United States.
Ross C; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, California, United States.
Shamloo K; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, California, United States.
Jhanji V; Department of Ophthalmology, School of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.
Zhang M; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, California, United States.
Sharma A; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Chapman University, Irvine, California, United States.
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 Sep 01; Vol. 61 (11), pp. 3.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Epithelium, Corneal/*metabolism
Glucose/*pharmacology
RNA, Messenger/*genetics
Tight Junction Proteins/*genetics
Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cells, Cultured ; Epithelium, Corneal/cytology ; Humans ; Immunoblotting ; RNA, Messenger/metabolism ; Tight Junction Proteins/biosynthesis ; Tight Junctions/drug effects ; Tight Junctions/metabolism
Czasopismo naukowe
Tytuł :
Alteration of Colonic Mucosal Permeability during Antibiotic-Induced Dysbiosis.
Autorzy :
Ran Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.; Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.
Fukui H; Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.
Xu X; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.; Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.
Wang X; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.; Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.
Ebisutani N; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Tanaka Y; R&D Center, Biofermin Pharmaceutical Co., Ltd., 7-3-4, Higashi-machi, Ibukidai, Nishi-ku, Kobe 651-2242, Japan.
Maeda A; R&D Center, Biofermin Pharmaceutical Co., Ltd., 7-3-4, Higashi-machi, Ibukidai, Nishi-ku, Kobe 651-2242, Japan.
Makizaki Y; R&D Center, Biofermin Pharmaceutical Co., Ltd., 7-3-4, Higashi-machi, Ibukidai, Nishi-ku, Kobe 651-2242, Japan.
Ohno H; R&D Center, Biofermin Pharmaceutical Co., Ltd., 7-3-4, Higashi-machi, Ibukidai, Nishi-ku, Kobe 651-2242, Japan.
Kondo T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Kono T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Tozawa K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Tomita T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Oshima T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
Miwa H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa, Nishinomiya 663-8501, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 25; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*adverse effects
Bacteria/*classification
Dysbiosis/*metabolism
Intestinal Mucosa/*metabolism
Tight Junction Proteins/*metabolism
Administration, Oral ; Animals ; Anti-Bacterial Agents/administration & dosage ; Bacteria/genetics ; Bacteria/isolation & purification ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Dysbiosis/chemically induced ; Dysbiosis/genetics ; Feces/microbiology ; Humans ; Intestinal Mucosa/drug effects ; Mice ; Permeability/drug effects ; Phylogeny ; Polymyxin B/administration & dosage ; Polymyxin B/adverse effects ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, RNA ; Tight Junction Proteins/genetics ; Vancomycin/administration & dosage ; Vancomycin/adverse effects
Czasopismo naukowe
Tytuł :
Effect of phytase on nutrient digestibility and expression of intestinal tight junction and nutrient transporter genes in pigs.
Autorzy :
Lu H; Department of Animal Sciences, Purdue University, West Lafayette, IN.
Shin S; Department of Animal Sciences, Purdue University, West Lafayette, IN.
Kuehn I; AB Vista, Darmstadt, Germany.
Bedford M; AB Vista - A division of AB Agri Ltd., Marlborough, Wiltshire, UK.
Rodehutscord M; Institute of Animal Science, University of Hohenheim, Stuttgart, Germany.
Adeola O; Department of Animal Sciences, Purdue University, West Lafayette, IN.
Ajuwon KM; Department of Animal Sciences, Purdue University, West Lafayette, IN.
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Źródło :
Journal of animal science [J Anim Sci] 2020 Jul 01; Vol. 98 (7).
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms :
6-Phytase/*pharmacology
Digestion/*drug effects
Swine/*physiology
Tight Junction Proteins/*metabolism
Tight Junctions/*genetics
Animal Feed/analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Calcium, Dietary/metabolism ; Diet/veterinary ; Dietary Supplements ; Digestion/physiology ; Feces ; Gastrointestinal Tract/metabolism ; Ileum/metabolism ; Inositol/administration & dosage ; Male ; Nutrients ; Phosphorus/metabolism ; Phosphorus, Dietary/metabolism ; Phytic Acid/metabolism ; Tight Junction Proteins/genetics ; Tight Junctions/metabolism
Czasopismo naukowe
Tytuł :
Dietary Ginkgo biloba leaf extracts supplementation improved immunity and intestinal morphology, antioxidant ability and tight junction proteins mRNA expression of hybrid groupers (Epinephelus lanceolatus ♂ × Epinephelus fuscoguttatus ♀) fed high lipid diets.
Autorzy :
Tan X; Guangdong Provincial Water Environment and Aquatic Products Security Engineering Technology Research Center, Guangzhou Key Laboratory of Aquatic Animal Diseases and Waterfowl Breeding, College of Animal Sciences and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong, 510225, China. Electronic address: .
Sun Z; Institute of Modern Aquaculture Science and Engineering, Guangzhou Key Laboratory of Subtropical Biodiversity and Biomonitoring, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Science, South China Normal University, Guangzhou, 510631, PR China.
Ye C; Institute of Modern Aquaculture Science and Engineering, Guangzhou Key Laboratory of Subtropical Biodiversity and Biomonitoring, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Science, South China Normal University, Guangzhou, 510631, PR China. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2020 Mar; Vol. 98, pp. 611-618. Date of Electronic Publication: 2019 Sep 15.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
Antioxidants/*metabolism
Bass/*immunology
Immunity, Innate/*drug effects
Intestines/*anatomy & histology
Plant Extracts/*metabolism
Tight Junction Proteins/*genetics
Animal Feed/analysis ; Animals ; Diet/veterinary ; Dietary Supplements/analysis ; Dose-Response Relationship, Drug ; Fish Proteins/genetics ; Fish Proteins/metabolism ; Intestines/drug effects ; Lipids/analysis ; Plant Extracts/administration & dosage ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Random Allocation ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
Polysaccharide fraction from greens of Raphanus sativus alleviates high fat diet-induced obesity.
Autorzy :
Do MH; Research Group of Functional Food Materials, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea. Electronic address: .
Lee HB; Research Group of Functional Food Materials, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea; Department of Food Science and Technology, Jeonbuk National University, Jeollabuk-do, 54896, Republic of Korea. Electronic address: .
Oh MJ; Technical Assistance Center, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea. Electronic address: .
Jhun H; Technical Assistance Center, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea. Electronic address: .
Choi SY; Research Group of Functional Food Materials, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea. Electronic address: .
Park HY; Research Group of Functional Food Materials, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 May 01; Vol. 343, pp. 128395. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Obesity/*prevention & control
Polysaccharides/*administration & dosage
Raphanus/*metabolism
Adipose Tissue, White/drug effects ; Adipose Tissue, White/metabolism ; Animals ; Biomarkers/blood ; Colon/drug effects ; Colon/physiology ; Diet, High-Fat ; Gastrointestinal Microbiome/drug effects ; Lipid Metabolism/drug effects ; Lipid Metabolism/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/pathology ; Plant Leaves/metabolism ; Plant Stems/metabolism ; Polysaccharides/metabolism ; Polysaccharides/pharmacology ; Principal Component Analysis ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
Effects of subacute ruminal acidosis on colon epithelial morphological structure, permeability, and expression of key tight junction proteins in dairy goats.
Autorzy :
Wang MY; Institute of Animal Nutrition and Feed, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, P.R. China; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, P.R. China; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, P.R. China.
Li Y; Institute of Animal Nutrition and Feed, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, P.R. China; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, P.R. China.
Gao M; Institute of Animal Nutrition and Feed, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, P.R. China.
Song LW; Institute of Animal Nutrition and Feed, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, P.R. China.
Xu M; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, P.R. China.
Zhao XL; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, P.R. China.
Jia Y; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, P.R. China.
Zhao M; Institute of Animal Nutrition and Feed, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, P.R. China.
Sun YY; College of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, P.R. China.
Hu HL; Institute of Animal Nutrition and Feed, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, P.R. China. Electronic address: .
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Źródło :
Journal of dairy science [J Dairy Sci] 2021 Apr; Vol. 104 (4), pp. 4260-4270. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms :
Acidosis*/veterinary
Cattle Diseases*
Goat Diseases*
Animals ; Cattle ; Colon ; Diet/veterinary ; Female ; Goats ; Hydrogen-Ion Concentration ; Lactation ; Permeability ; Rumen ; Tight Junction Proteins/genetics
Czasopismo naukowe
Tytuł :
PARP-1 induces EMT in non-small cell lung carcinoma cells via modulating the transcription factors Smad4, p65 and ZEB1.
Autorzy :
Kumar M; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Jaiswal RK; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Prasad R; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Yadav SS; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Kumar A; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Yadava PK; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India. Electronic address: .
Singh RP; School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 118994. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
Epithelial-Mesenchymal Transition*/genetics
Carcinoma, Non-Small-Cell Lung/*pathology
Lung Neoplasms/*pathology
Poly (ADP-Ribose) Polymerase-1/*metabolism
Smad4 Protein/*metabolism
Transcription Factor RelA/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Biomarkers, Tumor/metabolism ; Carcinoma, Non-Small-Cell Lung/genetics ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cell Movement/genetics ; Down-Regulation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Lentivirus/metabolism ; Lung Neoplasms/genetics ; Models, Biological ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism ; Tight Junction Proteins/metabolism ; Tumor Stem Cell Assay ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
A Commonly Used Biocide 2-N-octyl-4-isothiazolin-3-oneInduces Blood-Brain Barrier Dysfunction via Cellular Thiol Modification and Mitochondrial Damage.
Autorzy :
Kim D; College of Pharmacy Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 15588, Korea.
Kim EH; College of Pharmacy Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 15588, Korea.
Choi S; College of Pharmacy Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 15588, Korea.
Lim KM; College of Pharmacy, Ewha Womans University, Seoul 03760, Korea.
Tie L; Department of Pharmacology, School of Basic Medical Science, Peking University, Beijing 100083, China.
Majid A; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2TN, UK.
Bae ON; College of Pharmacy Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 15588, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 04; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Blood-Brain Barrier/*drug effects
Blood-Brain Barrier/*metabolism
Disinfectants/*toxicity
Thiazoles/*toxicity
Acetylcysteine/pharmacology ; Animals ; Antioxidants/pharmacology ; Blood-Brain Barrier/pathology ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Cell Death/drug effects ; Cell Line ; Disinfectants/antagonists & inhibitors ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Energy Metabolism/drug effects ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondria/pathology ; Proteolysis/drug effects ; Reactive Oxygen Species/metabolism ; Sulfhydryl Compounds/metabolism ; Thiazoles/antagonists & inhibitors ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
In Vivo Transplantation of Human Intestinal Organoids Enhances Select Tight Junction Gene Expression.
Autorzy :
Boyle MA; Department of Pediatric Surgery, McGovern Medical School at UTHealth, Houston, Texas.
Sequeira DJ; Department of Pediatric Surgery, McGovern Medical School at UTHealth, Houston, Texas.
McNeill EP; Department of Pediatric Surgery, McGovern Medical School at UTHealth, Houston, Texas.
Criss ZK 2nd; Department of Medicine Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas.
Shroyer NF; Department of Medicine Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas.
Speer AL; Department of Pediatric Surgery, McGovern Medical School at UTHealth, Houston, Texas. Electronic address: .
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Źródło :
The Journal of surgical research [J Surg Res] 2021 Mar; Vol. 259, pp. 500-508. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Tissue Engineering*
Intestines/*cytology
Organoids/*transplantation
Short Bowel Syndrome/*surgery
Tight Junction Proteins/*metabolism
Animals ; Cell Culture Techniques/methods ; Cell Line ; Gene Expression Regulation ; Human Embryonic Stem Cells ; Humans ; Male ; Mice ; Models, Animal ; Tight Junctions/metabolism
Czasopismo naukowe
Tytuł :
Ethanol extract of Centella asiatica alleviated dextran sulfate sodium-induced colitis: Restoration on mucosa barrier and gut microbiota homeostasis.
Autorzy :
Li H; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, PR China.
Chen X; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, PR China.
Liu J; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China.
Chen M; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, PR China.
Huang M; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China.
Huang G; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, PR China.
Chen X; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China.
Du Q; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China.
Su J; Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, PR China. Electronic address: .
Lin R; Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong, PR China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113445. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Bacteria/*drug effects
Colitis, Ulcerative/*prevention & control
Colon/*drug effects
Gastrointestinal Agents/*pharmacology
Gastrointestinal Microbiome/*drug effects
Intestinal Mucosa/*drug effects
Plant Extracts/*pharmacology
Triterpenes/*pharmacology
Animals ; Bacteria/growth & development ; Colitis, Ulcerative/chemically induced ; Colitis, Ulcerative/metabolism ; Colitis, Ulcerative/microbiology ; Colon/metabolism ; Colon/microbiology ; Colon/pathology ; Dextran Sulfate ; Disease Models, Animal ; Ethanol/chemistry ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/microbiology ; Intestinal Mucosa/pathology ; Male ; Mice, Inbred BALB C ; Permeability ; Serotonin/metabolism ; Solvents/chemistry ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
Evaluating the effect of ozone in UV induced skin damage.
Autorzy :
Ferrara F; Plants for Human Health Institute Animal Science Dept., NC Research Campus Kannapolis, NC, 28081, United States; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Pambianchi E; Plants for Human Health Institute Animal Science Dept., NC Research Campus Kannapolis, NC, 28081, United States.
Woodby B; Plants for Human Health Institute Animal Science Dept., NC Research Campus Kannapolis, NC, 28081, United States.
Messano N; Plants for Human Health Institute Animal Science Dept., NC Research Campus Kannapolis, NC, 28081, United States.
Therrien JP; JP Therrien Consulting, LLC, United States.
Pecorelli A; Plants for Human Health Institute Animal Science Dept., NC Research Campus Kannapolis, NC, 28081, United States.
Canella R; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Valacchi G; Plants for Human Health Institute Animal Science Dept., NC Research Campus Kannapolis, NC, 28081, United States; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; Kyung Hee University, Department of Food and Nutrition, South Korea. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Mar 01; Vol. 338, pp. 40-50. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Ozone/*toxicity
Skin/*drug effects
Skin/*radiation effects
Ultraviolet Rays/*adverse effects
Humans ; Inflammation Mediators/metabolism ; Oxidation-Reduction ; Oxidative Stress/drug effects ; Oxidative Stress/radiation effects ; Skin/metabolism ; Skin/pathology ; Tight Junction Proteins/metabolism ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Aquaporin-5 regulation of cell-cell adhesion proteins: an elusive "tail" story.
Autorzy :
Login FH; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Palmfeldt J; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Cheah JS; Department of Biomedical Engineering, University of California, Davis, California.
Yamada S; Department of Biomedical Engineering, University of California, Davis, California.
Nejsum LN; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 Mar 01; Vol. 320 (3), pp. C282-C292. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aquaporin 5/*metabolism
Cell Adhesion/*physiology
Animals ; Cell Line ; Cell Membrane/metabolism ; Cell Movement/physiology ; Dogs ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition/physiology ; HEK293 Cells ; Humans ; Madin Darby Canine Kidney Cells ; Tight Junction Proteins/metabolism ; beta Catenin/metabolism ; gamma Catenin/metabolism
Czasopismo naukowe
Tytuł :
Acute Effects of Butyrate on Induced Hyperpermeability and Tight Junction Protein Expression in Human Colonic Tissues.
Autorzy :
Tabat MW; Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
Marques TM; Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
Markgren M; Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
Löfvendahl L; Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
Brummer RJ; Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
Wall R; Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, 701 82 Örebro, Sweden.
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Źródło :
Biomolecules [Biomolecules] 2020 May 14; Vol. 10 (5). Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Butyrates/*pharmacology
Colon/*drug effects
Intestinal Mucosa/*drug effects
Tight Junction Proteins/*metabolism
Adult ; Colon/cytology ; Colon/metabolism ; Electric Impedance ; Female ; Humans ; Intestinal Absorption ; Intestinal Mucosa/metabolism ; Male ; Middle Aged ; Tight Junction Proteins/genetics ; Transcytosis
Czasopismo naukowe
Tytuł :
Differential day-night expression of tight junction components in murine retinal pigment epithelium.
Autorzy :
Louer EMM; Dept of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; Dept of Ophthalmology, Donders Institute of Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.
Günzel D; Institute of Clinical Physiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
Rosenthal R; Institute of Clinical Physiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
Carmone C; Dept of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Yi G; Dept of Molecular Biology, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, the Netherlands.
Stunnenberg HG; Dept of Molecular Biology, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, the Netherlands.
den Hollander AI; Dept of Ophthalmology, Donders Institute of Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands; Dept of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: .
Deen PMT; Dept of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2020 Apr; Vol. 193, pp. 107985. Date of Electronic Publication: 2020 Feb 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Circadian Rhythm/*physiology
Retinal Photoreceptor Cell Outer Segment/*metabolism
Retinal Pigment Epithelium/*metabolism
Tight Junction Proteins/*genetics
Animals ; Male ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Retinal Pigment Epithelium/cytology ; Tight Junction Proteins/biosynthesis
Czasopismo naukowe
Tytuł :
Faecalibacterium prausnitzii-derived microbial anti-inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression.
Autorzy :
Xu J; Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Liang R; Department of Pediatrics, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Zhang W; Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.; Department of Gastroenterology, Guangdong Provincial Hospital of Chinese Medicine (2nd Clinical Hospital of Guangzhou University of Chinese Medicine), Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People's Republic of China.
Tian K; Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Li J; Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Chen X; Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska.
Yu T; Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Chen Q; Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Pokaż więcej
Źródło :
Journal of diabetes [J Diabetes] 2020 Mar; Vol. 12 (3), pp. 224-236. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Faecalibacterium prausnitzii/*metabolism
Intestinal Mucosa/*metabolism
Tight Junction Proteins/*metabolism
Tight Junctions/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Caco-2 Cells ; Diabetes Mellitus, Type 2/genetics ; Dysbiosis/genetics ; Dysbiosis/physiopathology ; Gastrointestinal Microbiome/drug effects ; Gastrointestinal Microbiome/genetics ; Gastrointestinal Microbiome/physiology ; Gene Expression/drug effects ; HEK293 Cells ; HT29 Cells ; Humans ; Inflammatory Bowel Diseases/genetics ; Inflammatory Bowel Diseases/metabolism ; Intestinal Mucosa/drug effects ; Mice ; Permeability/drug effects ; Tight Junction Proteins/genetics ; Tight Junctions/drug effects
Czasopismo naukowe

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