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Tytuł :
Characterization of a novel toll-like receptor and activation NF-κB signal pathway in triangle sail mussel Hyriopsis cumingii.
Autorzy :
Yin S; College of Life Sciences, Department of Aquatic Sciences, Nanchang University, Nanchang 330031, China.
Chen J; Preschool Education College of Shangrao, Shangrao 334000, China.
Zhu M; College of Life Sciences, Department of Aquatic Sciences, Nanchang University, Nanchang 330031, China.
BaoQingHu; College of Life Sciences, Department of Aquatic Sciences, Nanchang University, Nanchang 330031, China. Electronic address: .
Su F; College of Life Sciences, Department of Aquatic Sciences, Nanchang University, Nanchang 330031, China.
Jian S; College of Life Sciences, Department of Aquatic Sciences, Nanchang University, Nanchang 330031, China.
Wen C; College of Life Sciences, Department of Aquatic Sciences, Nanchang University, Nanchang 330031, China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Aug-Sep; Vol. 255, pp. 110608. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Bivalvia*/genetics
Bivalvia*/metabolism
Gene Expression Regulation*
NF-kappa B*/genetics
NF-kappa B*/metabolism
Signal Transduction*
Toll-Like Receptors*/genetics
Toll-Like Receptors*/metabolism
Hepatopancreas/*metabolism
Animals
Czasopismo naukowe
Tytuł :
Toll-like receptors, environmental caging, and lung dysbiosis.
Autorzy :
Lipinski JH; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Falkowski NR; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
Huffnagle GB; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan.
Erb-Downward JR; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Dickson RP; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan.
Moore BB; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan.
O'Dwyer DN; Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Aug 01; Vol. 321 (2), pp. L404-L415. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bacteria*/classification
Bacteria*/genetics
Bacteria*/growth & development
Microbiota*
Dysbiosis/*microbiology
Lung/*microbiology
Toll-Like Receptors/*deficiency
Animals ; Dysbiosis/genetics ; Dysbiosis/pathology ; Lung/pathology ; Mice ; RNA, Bacterial/genetics ; RNA, Ribosomal, 16S/genetics ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Infected Pediatric Cerebral Cortical Neurons: Transcriptomic Analysis and Potential Role of Toll-like Receptors in Pathogenesis.
Autorzy :
Gugliandolo A; IRCCS Centro Neurolesi 'Bonino-Pulejo', Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy.
Chiricosta L; IRCCS Centro Neurolesi 'Bonino-Pulejo', Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy.
Calcaterra V; Department of Pediatrics, Ospedale dei Bambini 'Vittore Buzzi', 20154 Milano, Italy.; Pediatrics and Adolescentology Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy.
Biasin M; Department of Biomedical and Clinical Sciences-L. Sacco, University of Milan, 20157 Milan, Italy.
Cappelletti G; Department of Biomedical and Clinical Sciences-L. Sacco, University of Milan, 20157 Milan, Italy.
Carelli S; Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan, 20157 Milan, Italy.
Zuccotti G; Department of Pediatrics, Ospedale dei Bambini 'Vittore Buzzi', 20154 Milano, Italy.; Department of Biomedical and Clinical Sciences-L. Sacco, University of Milan, 20157 Milan, Italy.
Avanzini MA; Cell Factory, Pediatric Hematology Oncology Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Bramanti P; IRCCS Centro Neurolesi 'Bonino-Pulejo', Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy.
Pelizzo G; Department of Biomedical and Clinical Sciences-L. Sacco, University of Milan, 20157 Milan, Italy.; Pediatric Surgery Unit, Ospedale dei Bambini 'Vittore Buzzi', 20154 Milano, Italy.
Mazzon E; IRCCS Centro Neurolesi 'Bonino-Pulejo', Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 28; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*metabolism
Cerebral Cortex/*metabolism
Neurons/*virology
SARS-CoV-2/*pathogenicity
Toll-Like Receptors/*metabolism
COVID-19/genetics ; COVID-19/immunology ; Child ; Cytokines/metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Neurons/immunology ; SARS-CoV-2/immunology ; SARS-CoV-2/metabolism ; Signal Transduction/genetics ; Toll-Like Receptors/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
Evolution of Toll, Spatzle and MyD88 in insects: the problem of the Diptera bias.
Autorzy :
Lima LF; Laboratório de Biologia Computacional e Sistemas, Oswaldo Cruz Foundation, Fiocruz, Rio de Janeiro, Brazil.
Torres AQ; Laboratório de Biologia Computacional e Sistemas, Oswaldo Cruz Foundation, Fiocruz, Rio de Janeiro, Brazil.
Jardim R; Laboratório de Biologia Computacional e Sistemas, Oswaldo Cruz Foundation, Fiocruz, Rio de Janeiro, Brazil.
Mesquita RD; Laboratório de Bioinformática, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular-INCT-EM, Rio de Janeiro, Brazil.
Schama R; Laboratório de Biologia Computacional e Sistemas, Oswaldo Cruz Foundation, Fiocruz, Rio de Janeiro, Brazil. .; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular-INCT-EM, Rio de Janeiro, Brazil. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Jul 21; Vol. 22 (1), pp. 562. Date of Electronic Publication: 2021 Jul 21.
Typ publikacji :
Journal Article
MeSH Terms :
Myeloid Differentiation Factor 88*/genetics
Toll-Like Receptors*/genetics
Toll-Like Receptors*/metabolism
Animals ; Evolution, Molecular ; Phylogeny ; Signal Transduction
Czasopismo naukowe
Tytuł :
Role of Endosomal TLRs in Staphylococcus aureus Infection.
Autorzy :
Lentini G; Department of Human Pathology, University of Messina, Messina, Italy.
Famà A; Department of Human Pathology, University of Messina, Messina, Italy.
De Gaetano GV; Department of Human Pathology, University of Messina, Messina, Italy.
Galbo R; Department of Chemical, Biological and Pharmaceutical Sciences, University of Messina, Messina, Italy.
Coppolino F; Department of Human Pathology, University of Messina, Messina, Italy.
Venza M; Department of Biomedical, Dental and Imaging Sciences, University of Messina, Messina, Italy; and.
Teti G; Charybdis Vaccines Srl, Messina, Italy .
Beninati C; Department of Human Pathology, University of Messina, Messina, Italy.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Sep 01; Vol. 207 (5), pp. 1448-1455. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endosomes/*metabolism
Membrane Glycoproteins/*metabolism
Neutrophils/*immunology
Staphylococcal Infections/*immunology
Staphylococcus aureus/*physiology
Toll-Like Receptor 7/*metabolism
Toll-Like Receptor 9/*metabolism
Toll-Like Receptors/*metabolism
Animals ; Cytokines/metabolism ; Disease Models, Animal ; Disease Susceptibility ; Female ; Humans ; Immunity, Innate ; Inflammation Mediators/metabolism ; Membrane Glycoproteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Toll-Like Receptor 7/genetics ; Toll-Like Receptor 9/genetics ; Toll-Like Receptors/genetics
Czasopismo naukowe
Tytuł :
Toll protein family structure, evolution and response of the whiteleg shrimp (Litopenaeus vannamei) to exogenous iridescent virus.
Autorzy :
Liu H; Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou, China.
Guo S; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen, China.; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.
He Y; Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou, China.
Shi Q; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen, China.; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.
Yang M; Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou, China.
You X; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen, China.; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.
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Źródło :
Journal of fish diseases [J Fish Dis] 2021 Aug; Vol. 44 (8), pp. 1131-1145. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Arthropod Proteins/*genetics
Iridoviridae/*physiology
Penaeidae/*genetics
Toll-Like Receptors/*genetics
Animals ; Arthropod Proteins/metabolism ; Penaeidae/virology ; Sequence Analysis, DNA ; Sequence Analysis, Protein ; Toll-Like Receptors/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Structural Evolution and Translational Potential for Agonists and Antagonists of Endosomal Toll-like Receptors.
Autorzy :
Talukdar A; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.; Academy of Scientific and Innovative Research, Ghaziabad 201002, Uttar Pradesh, India.
Ganguly D; IICB-Translational Research Unit of Excellence, Department of Cancer Biology and Inflammatory Disorders, CSIR-Indian Institute of Chemical Biology, CN6, Sector V, Salt Lake, Kolkata 700091, West Bengal, India.; Academy of Scientific and Innovative Research, Ghaziabad 201002, Uttar Pradesh, India.
Roy S; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.
Das N; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.; Academy of Scientific and Innovative Research, Ghaziabad 201002, Uttar Pradesh, India.
Sarkar D; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jun 24; Vol. 64 (12), pp. 8010-8041. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heterocyclic Compounds/*chemistry
Toll-Like Receptors/*agonists
Toll-Like Receptors/*antagonists & inhibitors
Animals ; Endosomes/chemistry ; HEK293 Cells ; Heterocyclic Compounds/metabolism ; Heterocyclic Compounds/pharmacology ; Humans ; Mice ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
Structural and functional understanding of the toll-like receptors.
Autorzy :
Asami J; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Shimizu T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
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Źródło :
Protein science : a publication of the Protein Society [Protein Sci] 2021 Apr; Vol. 30 (4), pp. 761-772. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunity, Innate*
Toll-Like Receptors*/chemistry
Toll-Like Receptors*/immunology
Signal Transduction/*immunology
Animals ; Humans ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Applications and practice of advanced drug delivery systems for targeting Toll-like receptors in pulmonary diseases.
Autorzy :
Chan Y; School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur 57000, Malaysia.
Prasher P; Department of Chemistry, University of Petroleum & Energy Studies, Energy Acres, Dehradun 248007, India.
Löbenberg R; University of Alberta, Faculty of Pharmacy & Pharmaceutical Sciences, Edmonton, AB T6G 2N8, Canada.
Gupta G; School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur 302017, India.
Singh SK; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, India.
Oliver BG; School of Life Sciences, Faculty of Science, University of Technology, Sydney NSW 2007, Australia.; Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia.
Chellappan DK; Department of Life Sciences, School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur 57000, Malaysia.
Dua K; University of Alberta, Faculty of Pharmacy & Pharmaceutical Sciences, Edmonton, AB T6G 2N8, Canada.; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI), University of Newcastle, New Lambton Heights, Newcastle, NSW 2305, Australia.
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Źródło :
Nanomedicine (London, England) [Nanomedicine (Lond)] 2021 Apr; Vol. 16 (10), pp. 783-786. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Editorial
MeSH Terms :
Lung Diseases*/drug therapy
Toll-Like Receptors*
Drug Delivery Systems ; Humans
Opinia redakcyjna
Tytuł :
In silico analyses on the comparative sensing of SARS-CoV-2 mRNA by the intracellular TLRs of humans.
Autorzy :
Choudhury A; Integrative Biochemistry & Immunology Laboratory, Department of Animal Science, Kazi Nazrul University, Asansol, West Bengal, India.
Das NC; Integrative Biochemistry & Immunology Laboratory, Department of Animal Science, Kazi Nazrul University, Asansol, West Bengal, India.
Patra R; Integrative Biochemistry & Immunology Laboratory, Department of Animal Science, Kazi Nazrul University, Asansol, West Bengal, India.
Mukherjee S; Integrative Biochemistry & Immunology Laboratory, Department of Animal Science, Kazi Nazrul University, Asansol, West Bengal, India.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Apr; Vol. 93 (4), pp. 2476-2486. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*virology
RNA, Messenger/*genetics
RNA, Viral/*metabolism
SARS-CoV-2/*metabolism
Toll-Like Receptors/*metabolism
Binding Sites ; COVID-19/immunology ; COVID-19/metabolism ; Computer Simulation ; Genome, Viral ; Humans ; Molecular Docking Simulation ; Protein Binding ; RNA, Messenger/analysis ; RNA, Messenger/metabolism ; RNA, Viral/chemistry ; RNA, Viral/genetics ; SARS-CoV-2/genetics ; Toll-Like Receptors/chemistry ; Toll-Like Receptors/genetics
Czasopismo naukowe
Tytuł :
Human prostate epithelial cells and prostate-derived stem cells malignantly transformed in vitro with sodium arsenite show impaired Toll like receptor -3 (TLR3)-associated anti-tumor pathway.
Autorzy :
Alvarado-Morales I; Laboratorio de Inmunotoxicología. Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Manuel Nava 6, Zona Universitaria, 78290, SLP, Mexico.
Olivares-Illana V; Laboratorio de Interacciones Biomoleculares y Cáncer, Instituto de Física, Universidad Autónoma de San Luis Potosí, Manuel Nava 6, Zona Universitaria, 78290, SLP, Mexico.
Arenas-Huertero C; Laboratorio de Biología, Facultad de Ciencias, Universidad Autónoma de San Luis Potosí. Av, Chapultepec, 1570. 78295, SLP, Mexico.
Reynaga-Hernández E; Laboratorio de Inmunotoxicología. Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Manuel Nava 6, Zona Universitaria, 78290, SLP, Mexico.
Layseca-Espinosa E; Centro de Investigación en Biomedicina y Salud, Facultad de Medicina, Universidad autónoma de San Luis Potosí, Sierra Leona 550 Lomas de San Luis, 78210, SLP, Mexico.
Tokar EJ; National Toxicology Program Laboratory, NTP. National Institutitute of Environmental Health Sciences, NIEHS, Durham, NC, 27709, United States.
Escudero-Lourdes C; Laboratorio de Inmunotoxicología. Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Manuel Nava 6, Zona Universitaria, 78290, SLP, Mexico. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Oct 10; Vol. 350, pp. 185-193. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Epithelial Cells/*drug effects
Epithelial Cells/*metabolism
Neoplastic Stem Cells/*drug effects
Neoplastic Stem Cells/*metabolism
Prostatic Neoplasms/*genetics
Prostatic Neoplasms/*metabolism
Sodium Compounds/*toxicity
Toll-Like Receptors/*drug effects
Adult ; Aged ; Aged, 80 and over ; Apoptosis/drug effects ; Cell Transformation, Neoplastic/drug effects ; Cell Transformation, Neoplastic/metabolism ; Cells, Cultured/drug effects ; Cells, Cultured/metabolism ; Genetic Variation ; Genotype ; Humans ; Male ; Middle Aged ; Prostate/drug effects ; Prostate/metabolism ; Prostatic Neoplasms/physiopathology ; Sodium Compounds/metabolism ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
The extreme C-terminus of IRAK2 assures full TRAF6 ubiquitination and optimal TLR signaling.
Autorzy :
Joshi H; Institute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Lunz B; Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.
Peters A; Institute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Zölch M; Institute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Berberich I; Institute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Berberich-Siebelt F; Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2021 Jun; Vol. 134, pp. 172-182. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-1 Receptor-Associated Kinases/*metabolism
Signal Transduction/*immunology
TNF Receptor-Associated Factor 6/*metabolism
Toll-Like Receptors/*metabolism
Animals ; HEK293 Cells ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Interleukin-1 Receptor-Associated Kinases/immunology ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; RAW 264.7 Cells ; TNF Receptor-Associated Factor 6/immunology ; Toll-Like Receptors/immunology ; Ubiquitination
Czasopismo naukowe
Tytuł :
Association between Toll-like receptor gene polymorphisms and risk of Helicobacter pylori infection: A protocol for systematic review and meta-analysis.
Autorzy :
Ma X; Graduate School, Guangxi University of Chinese Medicine.
Lu L; Graduate School, Guangxi University of Chinese Medicine.
Tang Y; Graduate School, Guangxi University of Chinese Medicine.
Luo W; Department of Gastroenterology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine.
Li J; Department of Cardiology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Tang M; Graduate School, Guangxi University of Chinese Medicine.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 May 07; Vol. 100 (18), pp. e25729.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Predisposition to Disease*
Helicobacter Infections/*epidemiology
Toll-Like Receptors/*genetics
Case-Control Studies ; Helicobacter Infections/diagnosis ; Helicobacter Infections/genetics ; Helicobacter pylori/isolation & purification ; Helicobacter pylori/metabolism ; Humans ; Meta-Analysis as Topic ; Pathogen-Associated Molecular Pattern Molecules/metabolism ; Polymorphism, Single Nucleotide ; Systematic Reviews as Topic ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
The immunogenic maturation of goat monocyte-derived dendritic cells and upregulation of toll-like receptors by five antigens of Haemonchus contortus in-vitro.
Autorzy :
Hasan MW; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Haseeb M; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Ehsan M; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, Gansu, China. Electronic address: .
Gadahi JA; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China; Department of Veterinary Parasitology, Sindh Agriculture University Tandojam, Pakistan.
Wang Q; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Memon MA; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Aleem MT; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Lakho SA; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Yan RF; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Xu LX; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Song XK; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
Li X; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China. Electronic address: .
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Źródło :
Research in veterinary science [Res Vet Sci] 2021 May; Vol. 136, pp. 247-258. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Antigens, Helminth/*immunology
Dendritic Cells/*immunology
Goats/*immunology
Haemonchus/*immunology
Toll-Like Receptors/*genetics
Animals ; Monocytes/immunology ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł :
Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation.
Autorzy :
Katebi A; Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR, Iran. Electronic address: .
Varshochian R; Department of Pharmaceutics, Shahid Beheshti University of Medical Sciences, Tehran, IR, Iran; Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IR, Iran. Electronic address: .
Riazi-Rad F; Department of Immunology, Pasteur Institute of Iran, Tehran, IR, Iran. Electronic address: .
Ganjalikhani-Hakemi M; Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR, Iran. Electronic address: .
Ajdary S; Department of Immunology, Pasteur Institute of Iran, Tehran, IR, Iran. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 May; Vol. 137, pp. 111276. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Protozoan/*pharmacology
Imidazoles/*pharmacology
Leishmania major/*drug effects
Leishmaniasis, Cutaneous/*drug therapy
Lipopeptides/*pharmacology
Macrophage Activation/*drug effects
Macrophages/*drug effects
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Toll-Like Receptors/*agonists
Trypanocidal Agents/*pharmacology
Animals ; Antigens, Protozoan/chemistry ; Cell Line ; Cytokines/genetics ; Cytokines/metabolism ; Drug Carriers ; Drug Compounding ; Host-Parasite Interactions ; Imidazoles/chemistry ; Leishmania major/pathogenicity ; Leishmaniasis, Cutaneous/genetics ; Leishmaniasis, Cutaneous/metabolism ; Leishmaniasis, Cutaneous/parasitology ; Lipopeptides/chemistry ; Macrophages/metabolism ; Macrophages/parasitology ; Mice ; Nanoparticles ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Parasite Load ; Signal Transduction ; Toll-Like Receptors/metabolism ; Trypanocidal Agents/chemistry
Czasopismo naukowe
Tytuł :
Innate and humoral immune parameters at delivery in colostrum and calves from heifers experimentally infected with Neospora caninum.
Autorzy :
Maldonado Rivera JE; Faculty of Agrarian Sciences, National University of Mar del Plata, Argentina; Faculty of Agricultural Sciences, University of Cuenca, Ecuador.
Hecker YP; Institute of Innovation for Agricultural Production and Sustainable Development (IPADS Balcarce), Argentina.
Burucúa MM; Institute of Innovation for Agricultural Production and Sustainable Development (IPADS Balcarce), Argentina.
Cirone KM; Faculty of Agrarian Sciences, National University of Mar del Plata, Argentina; National Institute of Agricultural Technology (INTA), Argentina.
Cheuquepán FA; Institute of Innovation for Agricultural Production and Sustainable Development (IPADS Balcarce), Argentina.
Fiorani F; Faculty of Agrarian Sciences, National University of Mar del Plata, Argentina; Institute of Innovation for Agricultural Production and Sustainable Development (IPADS Balcarce), Argentina.
Dorsch MA; Faculty of Agrarian Sciences, National University of Mar del Plata, Argentina.
Colque LA; Faculty of Agrarian Sciences, National University of Mar del Plata, Argentina; National Institute of Agricultural Technology (INTA), Argentina.
Cantón GJ; National Institute of Agricultural Technology (INTA), Argentina.
Marin MS; Institute of Innovation for Agricultural Production and Sustainable Development (IPADS Balcarce), Argentina.
Moore DP; Faculty of Agrarian Sciences, National University of Mar del Plata, Argentina; Institute of Innovation for Agricultural Production and Sustainable Development (IPADS Balcarce), Argentina. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2021 Apr; Vol. 132, pp. 53-59. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Humoral*
Immunity, Innate*
Cattle/*immunology
Colostrum/*immunology
Gene Expression Regulation, Developmental/*immunology
Neospora/*immunology
Toll-Like Receptors/*metabolism
Animals ; Antibodies, Protozoan/immunology ; Cattle/embryology ; Cattle/metabolism ; Cattle/parasitology ; Cattle Diseases/genetics ; Cattle Diseases/immunology ; Cattle Diseases/metabolism ; Cattle Diseases/parasitology ; Female ; Immunoglobulin G/immunology ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/metabolism ; Pregnancy ; Proteins/genetics ; Proteins/metabolism ; Toll-Like Receptor 7/genetics ; Toll-Like Receptor 7/metabolism ; Toll-Like Receptors/genetics ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Umbilical Cord/metabolism
Czasopismo naukowe
Tytuł :
TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection.
Autorzy :
Owen AM; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, United States.
Fults JB; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, United States.; University of Texas Southwestern Medical School, Dallas, TX, United States.
Patil NK; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, United States.
Hernandez A; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, United States.
Bohannon JK; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, United States.; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Feb 18; Vol. 11, pp. 622614. Date of Electronic Publication: 2021 Feb 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunity, Innate*
Immunotherapy*
Infections*/immunology
Infections*/therapy
Toll-Like Receptors*/agonists
Toll-Like Receptors*/immunology
Signal Transduction/*immunology
Humans
Czasopismo naukowe
Tytuł :
Genome-wide analysis of Toll-like receptors in zebrafish and the effect of rearing temperature on the receptors in response to stimulated pathogen infection.
Autorzy :
Chen H; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Liang Y; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Han Y; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Liu T; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Chen S; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
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Źródło :
Journal of fish diseases [J Fish Dis] 2021 Mar; Vol. 44 (3), pp. 337-349. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Temperature*
Fish Diseases/*immunology
Toll-Like Receptors/*genetics
Zebrafish/*immunology
Animals ; Female ; Immunity, Innate/drug effects ; Immunity, Innate/genetics ; Lipopolysaccharides/pharmacology ; Male ; Phylogeny ; Poly I-C/pharmacology ; Sequence Alignment ; Teichoic Acids/pharmacology ; Toll-Like Receptors/immunology ; Zebrafish/genetics
Czasopismo naukowe
Tytuł :
Innate Receptor Activation Patterns Involving TLR and NLR Synergisms in COVID-19, ALI/ARDS and Sepsis Cytokine Storms: A Review and Model Making Novel Predictions and Therapeutic Suggestions.
Autorzy :
Root-Bernstein R; Department of Physiology, Michigan State University, East Lansing, MI 48824, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 20; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acute Lung Injury/*immunology
COVID-19/*immunology
Cytokine Release Syndrome/*immunology
NLR Proteins/*immunology
Respiratory Distress Syndrome/*immunology
Sepsis/*immunology
Toll-Like Receptors/*immunology
Acute Lung Injury/drug therapy ; Acute Lung Injury/metabolism ; Animals ; COVID-19/drug therapy ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/metabolism ; Humans ; Inflammation/drug therapy ; Inflammation/immunology ; Respiratory Distress Syndrome/drug therapy ; Respiratory Distress Syndrome/metabolism ; SARS-CoV-2/immunology ; Sepsis/drug therapy ; Sepsis/metabolism ; Toll-Like Receptors/metabolism
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Expatiating the molecular approaches of HMGB1 in diabetes mellitus: Highlighting signalling pathways via RAGE and TLRs.
Autorzy :
Behl T; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India. .
Sharma E; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Sehgal A; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Kaur I; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Kumar A; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Arora R; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Pal G; Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Kakkar M; Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Kumar R; Cardiovascular Research Institute, Icahn School of Medicine, New York, USA.
Bungau S; Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
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Źródło :
Molecular biology reports [Mol Biol Rep] 2021 Feb; Vol. 48 (2), pp. 1869-1881. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetes Mellitus/*immunology
Diabetes Mellitus/*metabolism
HMGB1 Protein/*metabolism
Receptor for Advanced Glycation End Products/*metabolism
Toll-Like Receptors/*metabolism
Animals ; Cytokines/metabolism ; Diabetes Mellitus/drug therapy ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; HMGB1 Protein/antagonists & inhibitors ; HMGB1 Protein/genetics ; HMGB1 Protein/immunology ; Humans ; Inflammation/drug therapy ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; NF-kappa B/metabolism ; Receptor for Advanced Glycation End Products/genetics ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Toll-Like Receptors/immunology
Czasopismo naukowe

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